Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(34)
- Tuncer, Metin(11)
- Merdan, Mehmet(10)
- Emirza, Elif Güzide(9)
- Yilmaz, Coskun(9)
- Baltaci, Cemalettin(8)
- Baltacı, Cemalettin(8)
- Tuncer, Gülsüm Zekiye(8)
- Türkkan, Tuğba(8)
- Dinç, Artum(7)
- Araz, Onur(6)
- Bekar, Fevziye(6)
- Cakir, Mehmet Ali(6)
- Ceylan, Levent(6)
- Duran, Celal(6)
- Koçak, Tevfik(6)
- Ozdes, Duygu(6)
- Soydaş, Şafak Sönmez(6)
- Akmeşe, Osman(5)
- Akyol, Hikmet(5)
- Bayrak, Nurten Gülsüm(5)
- Bayrakdaroglu, Serdar(5)
- Bülbül, Kenan(5)
- Ceylan, Halil Ibrahim(5)
- Gücer, Mehmet Ali(5)
- Karimullah, Suud Sarim(5)
- Kavuran, Korhan(5)
- Kaygusuz, Abdullah(5)
- Kulakaç, Nurşen(5)
- Kurnaz, Muammer(5)
- Saydam Eker, Çiğdem(5)
- Turk, Veysel(5)
- Öztürk, Serkan(5)
- (Alieva), Vildane Özkan(4)
- Abada, A.(4)
- Abbrescia, M.(4)
- Abdolmaleki, H.(4)
- Abidi, S. H.(4)
- Abramov, A.(4)
- Adam, C.(4)
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ4September 25, 2024 Yumrukaya-Tatvan (Bitlis, Türkiye) earthquake and a seismo-tectonic evaluation of its impact on the earthquake hazard in the region; [25 Eylül 2024 Yumrukaya-Tatvan (Bitlis, Türkiye) depremi ve bölgedeki deprem tehlikesine etkisi üzerine sismo-tektonik bir değerlendirme]
Öztürk, Serkan; Alkan, Hamdi
The current and future earthquake hazard in and around Bitlis were tired to reveal by utilizing the September 25, 2024, Yumrukaya-Tatvan earthquake (Mw=4.5) and its aftershocks, b-value and Z-value distributions, occurrence probabilities and recurrence periods of earthquakes and variations in Coulomb stress within the scope of this study. Also, it was tried to determine which fault systems in the study area is related to the Yumrukaya-Tatvan mainshock, characterized by strike-slip faulting. b-value in G-R relation was computed as 0.84∓0.06 and small b-values (<1.0) were imaged in the north-northwest-southeast directions throughout the South East Anatolian Thrust Zone and Muş Fault Zone, and west of Lake Van. At the beginning of 2025, significant seismic quiescence was observed near the Muş Fault Zone and the south and southeast of the South East Anatolian Thrust Zone. Recurrence periods for the events with the magnitudes of Mw=5.0, 5.5 and 6.2 were computed as ~10, ~26 and ~100 years, respectively. Additionally, occurrence probabilities of earthquakes with these magnitudes in the intermediate-term (~10 years) were calculated as ~64%, ~32% and ~10%, respectively. Positive Coulomb stress changes carry out a movement from the Kavakbaşı Fault zone in the west and the Beğendik segment in the east toward the South East Anatolian Thrust Zone in the east-southeast. In this region, there is no active fault/fault system according to the General Directorate of Mineral Research and Exploration. Thus, these findings are significant clues showing that multiple parameter seismo-tectonic analyses are important in determining the earthquake hazard for the September 25, 2024 earthquake, and that regions with small b-values and seismic quiescence and regions with positive Coulomb stress changes may indicate current hazard and possible earthquake zones in the future.
AtıfScopus2OpenAlex2TR Dizin1
İncele - MakaleAçık Erişim2025Scopus SJRQ3Investigation of fractional order covid-19 model with q-homotopy analysis transform method
Merdan, Mehmet; Açikgöz, Pınar
The primary objective of this paper is to derive approximate analytic solutions for the time fractional-order Covid-19 model by employing the q-homotopy analysis transform method (q-HATM) and the Laplace transform homotopy perturbation method (LT-HPM). The covid 19 model is a system of five-dimensional nonlinear ordinary differential equations. Moreover, this method applies even to more complex partial differential equations originating from mathematical biology, demonstrating computational efficiency and wide application. In this study, Caputo fractional derivative is used to obtain the fractional system and Laplace transformation is applied to analyze the approximate solutions of the system. Graphical results are presented and discussed quantitatively to illustrate the approximate solution. Copyright 2021, Yıldız Technical University.
- MakaleAçık Erişim2025Scopus SJRQ1The First Surgery Experienced Through Virtual Reality: A Knee Surgery Case Report
Aydin, Aydanur; Menekşeoğlu, Ahmet Kıvanç; Öner, Kerim; Ertürk, Engin
The decision to undergo surgery and the significance of the operating theater environment are influenced by several factors, which vary from person to person. Negative perceptions of the operating room environment can influence the decision to undergo surgery and the process of treatment. Virtual reality (VR) technology offers the potential to alter individuals' environmental encounters through the provision of diverse environmental perceptions. This case study evaluates the results of a VR simulation applied during surgery to an individual with no previous surgical experience. A male patient scheduled for arthroscopic meniscus surgery was the subject of a VR simulation. The patient's perception of the simulated environment was transmitted through VR goggles from the time he entered the operating room until he left. However, the VR application was terminated during the administration of anesthesia, and no premedication was administered to the patient. The VR application included nature walks in various regions, including forests, lakeshores, and meadows, accompanied by the sound of birds. Data were collected using a visual analog scale to assess pain levels and a walking test form. The patient, a 35-year-old male, is a high school graduate and is undergoing his first surgical procedure. The patient expressed concerns and fears regarding the decision to undergo surgery. The patient's preoperative anxiety was rated at 9 out of 10 but subsequently decreased to 1 out of 10 following the surgical procedure. The patient rated his satisfaction with the surgical experience as 9 out of 10. The patient did not require sedatives or analgesics during the intraoperative period or for the first 10 hours following the operation. The patient was successfully mobilized at the 15-hour mark following surgery. The patient was highly satisfied with the application. The utilization of VR during surgical procedures has the potential to reduce the necessity for premedication and enhance postoperative compliance among patients.
AtıfScopus1WoS1OpenAlex1
İncele - MakaleAçık Erişim2025Scopus SJRQ2Investigation of virulence factor genes and biofilm formation of antibiotic resistant clinical E.coli isolates
Mumin, Yahye Mohamud; Yüksel, Gamze; Özad Düzgün, Azer
Purpose: The aim of this study is to investigate the antibiotic sensitivity, presence of virulence genes and biofilm formation capacity of 90 clinical E. coli isolates. Methods: The presence of virulence genes in E. coli isolates were investigated by PCR. Ninety clinical isolates of E. coli were subjected to biofilm quantitative analysis using the semi-quantitative crystal violet staining method. Results: it was observed that the isolates were resistant to quinolone, cephalosporin, aminoglycoside, carbapenem and penicillin group antibiotics. The presence of virulence factor genes were observed in a total of 86/90 E. coli. The highest rate of fim (92.2 %) virulence factor gene was detected in the strains. Afa, pap, cnf, sfa, hly were detected in 30 %, 13 %, 13 %, 3.3 %, 2.2 % respectively. Also, 13 different virulence factor gene patterns were determined in 90 E. coli isolates. Of the 90 E. coli isolates whose biofilm-forming capacities were evaluated, 42 were found to have biofilm-forming capacity. Of these 26 (28.8 %) the weak, 12 (13.3 %) moderate and 4 (4.4 %) strong biofilm-forming. Also, statistical analysis was performed to investigate the relationship between virulence factor genes and biofilm formation, and none of the 7 genes analyzed showed a significant relationship with biofilm formation. Conclusion: since pathogenic E. coli is an important public health problem, investigating antibiotic resistance, virulence factor genes and biofilm formation in bacterial pathogens is important for better treatment options.
AtıfScopus4WoS4OpenAlex4İncele - Kitap BölümüYalnız künye2025Foundational Education of Primary-Level Refugee Students: Advancing Fundamental Subject Knowledge
Semercioğlu, Muhammed Serhat; Akçay, Ahmet Oğuz
This book comprehensively explores the educational experiences of refugee students in primary schools, specifically addressing literacy, mathematics, and science skills through innovative teaching methods, including artificial intelligence, coding, and drama-based etc. approaches. Embracing a skill-based learning, the book is enriched with practical applications designed to enhance essential skills among refugee learners effectively. Drawing upon the extensive expertise of contributing authors, each chapter provides in-depth analyses of various dimensions of refugee education, offering valuable insights into targeted pedagogical strategies. Chapters conclude with illustrative activities specifically designed for refugee students, accompanied by detailed evaluations of their outcomes. These activities are not merely theoretical; they are purposefully structured to ensure applicability and adaptability within diverse global educational contexts. This book serves as an essential resource for teacher candidates, educators, researchers, and academics specializing in refugee education and general pedagogy, combining rigorous theoretical perspectives with actionable, real-world strategies.
- MakaleAçık Erişim2025Scopus SJRQ1Characterization of thermal, chemical, mechanical, and fatigue behavior of 3D printed ABS-based elastomeric blends: ABS/EVA and ABS/TPU
Kuleyin, Hamdi; Budak, Selahattin; Yasan, Ömer Barışkan; Gümrük, Recep
The polymer blending method is widely used to obtain balanced mechanical properties and structural performance in many engineering applications. This study investigates the influence of Ethylene-Vinyl Acetate (EVA), and Thermoplastic Polyurethane (TPU) composition ratios on the thermal, chemical, viscoelastic, mechanical, and fatigue life behavior of Acrylonitrile-Butadiene-Styrene (ABS) based elastomeric blends. For this purpose, structural and mechanical properties of the blend material depending on their composition ratio were carried out through a series of characterization analyses, and tensile and fatigue tests. The findings indicated that ABS/EVA and ABS/TPU blends formed an immiscible structure. In addition, it was determined that the storage modulus of the blend with 10 % TPU improved because of the presence of new absorption peaks in the structure. The mechanical properties such as elastic modulus, yield strength, and ultimate tensile strength decreased concerning neat ABS with an increase in the EVA and TPU composition ratio for blend materials. However, the elongation to break was achieved approximately 6 times increasing with an increase in the TPU ratio for ABS/TPU blends. It was determined that the fatigue strength value in ABS/EVA and ABS/TPU blends decreased with the decrease in ABS composition ratio in the blend system. However, it was found that fatigue life improved by 25 % compared to ABS at low-stress amplitude for 10 % TPU additive. Finally, it can be revealed that the ABS-based elastomeric blends can be used to obtain desired properties according to their composition ratios for different applications.
AtıfScopus20WoS20OpenAlex20İncele - MakaleAçık Erişim2025Scopus SJRQ1Invisible Warriors in the Struggle Against Cancer: Social Support and Spiritual Care—A Phenomenological Study on Patient Experiences †
Özmaya, Esma; Uzun, Sevda
Objective: The aim of this study is to examine the effect of social support on the mental state of cancer patients using a phenomenological approach. Materials–Methods: In this study, a phenomenological research orientation was used, and semi-structured in-depth interviews were conducted with 14 people diagnosed with cancer living in a province in central Turkey. The criterion sampling method, one of the purposeful sampling methods, was used for the sample group. The interviews continued until data saturation was achieved, and all interviews were recorded and later transcribed verbatim. The data were analyzed using thematic analysis, and the study was conducted and reported according to the COREQ checklist. Results: Two categories (effects of cancer and needs of the cancer patient (invisible components)) and five themes (psychological effects, social effects, physical effects, social support, and spiritual care) were identified in the analysis of the data. Conclusions: It has been determined that individuals are affected by cancer mentally, physically, and socially, and have difficulty coping. In particular, it has been found that social support and thinking about the purpose of life, supporting hope, and self-acceptance are quite important in increasing individuals’ spirituality.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ2Assessing Internalized Beliefs: Psychometric Evidences for the Pathogenic Belief Scale in Turkish Culture
Türkkan, Tuğba; Odacı, Hatice; Kaya, Feridun
This study was conducted to test the reliability and validity of the Pathogenic Belief Scale (PBS) on adult individuals. Participants consisted of 299 adults, including 189 (63.2%) females and 110 (36.8%) males, with a mean age of 21.16 years (SD = 3.68). Personal Information Form, Pathogenic Belief Scale-R, Cognitive Distortions Scale, and Dysfunctional Attitude Scale were used as data collection tools. The three-dimensional structure of the PBS was confirmed by confirmatory factor analysis on the Turkish sample (χ2 = 204.990, df = 186, χ2/df = 1.102, comparative fit index = 0.997, normed fit index = 0.997, standardized root mean square residual =.058, and root-mean-square error of approximation =.019 (90% confidence interval [.001,.032]). Factor loadings were found to be between.470 and.761. The analyses also showed that the internal consistency reliability coefficients were at a quite good level for the undeserving dimension (α =.874, ω = 0.875), the cannot rely on others dimension (α =.794, ω = 0.799), and the interpersonal guilt dimension (α =.847, ω = 0.857). The Turkish version of the PBS is a valid and reliable tool that can be used to evaluate the pathogenic beliefs of individuals. The research results were discussed, and certain inferences were made for the future in line with the limitations.
AtıfScopus3WoS3OpenAlex3İncele - MakaleAçık Erişim2025Scopus SJRQ2Microencapsulation of Caucasian blueberries (Vaccinium arctostaphylos L.) anthocyanins: Colour stability in varying storage conditions
Girgin, Serpil; Üçüncü, Osman; Baltacı, Cemalettin; Muslu Aykoç, Ayşe
The aim of this study was to investigate the extraction of anthocyanins from the fruits of Caucasian blueberry (Vaccinium arctostaphylos L.) and examine the colour stability of anthocyanins encapsulated through spray drying in model systems. The trials were conducted to determine the optimal conditions for anthocyanin extraction using an ultrasonic water bath at temperatures of 25, 50 and 75°C. The ideal anthocyanin extraction occurred at 25°C using 100% acetone in an ultrasonic bath for 15 min at 35 kHz. Anthocyanin concentrations were evaluated using the pH differential method. The extracted anthocyanins were encapsulated through spray drying with maltodextrin as the encapsulating material. The encapsulation efficiency was 80.4 ± 0.20%, and the anthocyanin retention rate was 83.0 ± 0.76%. The coloured capsules were added to model systems with pH values of 4.50, 5.00, 5.50 and 6.00. The colour values (L* 50.16 ± 0.05, a* 4.08 ± 0.04, b* −9.35 ± 0.01, H° 293.57 ± 0.15, C* 10.20 ± 0.03) were measured during varying storage conditions. The results showed, that colour loss began on the fifth day and this was accelerated with higher temperatures and pH values. It was found that encapsulation significantly preserved the stability of the blue colour and the loss of the blue colour followed first-order reaction kinetics. The study showed that the blue colour of microcapsules was best preserved at pH 5.00 at 25°C. In this case, the measured total colour change (∆E) was 5.86, the activation energy (Ea) was 37.64 kJ/mol, and the half-life (t1/2) was determined to be 19.08 days.
AtıfScopus4WoS4OpenAlex3İncele - Kitap BölümüYalnız künye2025Nanotechnological Green Synthesis and Its Impact on Plant Science
Altuner, Elif Esra; Bozbeyoğlu, Pınar; Tekeli, Yener; Sen, Fatih
Nanotechnology is a multidisciplinary field that manipulates materials at the nanoscale, typically between 1 and 100 nanometers. It bridges various disciplines, including physics, chemistry, biology, engineering, and materials science, creating materials with unique properties that classical theories cannot predict. Nanotechnology is central to advancements in energy, medical therapies, environmental solutions, and electronics. Nanotechnology's ability to create more efficient energy storage systems, such as high-capacity batteries, and its potential to revolutionize healthcare by enabling personalized medicine further demonstrate its vast impact. These innovations offer solutions to pressing issues like clean energy, health care, and ecological preservation. This chapter focuses on green synthesis methods in plant science, highlighting environmentally friendly techniques for producing nanomaterials. These sustainable methods not only contribute to eco-friendly agricultural practices but also promote environmental conservation and sustainability in the field of nanotechnology.
AtıfScopus5OpenAlex3İncele - Kitap BölümüAçık Erişim2025Ensuring Circularity through Outsourcing Decisions in Solar Photovoltaic Supply Chains
Erol, Ismail; Peker, Iskender; Benli, Tolga; Ar, Ilker Murat
Because solar photovoltaic (SPv) panels have seen such significant cost reductions in recent years, it has proven to be by far the most dynamic forms of renewable power generation. However, the transition from linear to circular is also crucial for building sustainability in SPv supply chains. The circular economy (CE) is appealing in part because of its ability to bring economic and environmental development objectives together to ensure sustainable production and consumption. To aid in the shift to a more circular economy, several circular-based strategies for various functions such as procurement can be developed. In this study, critical success factors (CSFs) to ensure circular outsourcing structure in SPv supply chains are identified and scrutinized. To achieve this, a multi-criteria-based methodology is proposed. The findings of this study argue that understanding the actual implications of not converting to circular outsourcing (C12) is the most significant cause CSF. This study also provides several implications.
- MakaleAçık Erişim2025Scopus SJRQ1Kurtun Dam oscillate characterization with landslide possible effect detection using InSAR observations
Celik, Fatih; Sanli, Fusun Balik; Celik, Kemal; Celik, Ayse
Observing and analyzing areas prone to landslides is crucial due to the extensive destructive capacity of landslides. To monitor landslide activities across diverse areas, remote sensing data and image processing methods are employed. This study proposes a method that integrates Multi-temporal Interferometric Synthetic Aperture Radar and advanced temporal tracking technologies to intensify surveillance of the Kurtun Dam and its valley. According to Sentinel-1 A data, the net displacement rates of the dam crest varied between − 12 and 2 mm/year (LOS). InSAR technology surveys the entire dam catchment area, detecting critical infrastructure such as slopes, spillways, and access roads. The crest of the Kurtun Dam experiences oscillatory deformation during filling activities, but the lateral slopes and downstream abutment remain stable. As reservoir water levels rise, the dam structure exhibits downstream deformations, whereas declining water level results in upstream displacements. Monitoring points located the opposite Ozkurtun settlement and within the reservoir area, both facing the dam, exhibited displacement rates of up to -50 mm monthly. In regions susceptible to landslides, the greatest annual displacement rates were observed to be -54 and − 127 mm/year. This study suggests that integrating 3D modeling with InSAR technology into dam monitoring systems can significantly enhance their effectiveness. At Kurtun Dam and other crucial locations within the catchment area, the integrated approach combined with topographic monitoring, ensures reliable landslide detection and analysis. By advancing monitoring technology for embankment dams, this strategy prioritizes safety and structural integrity assessments.
AtıfScopus1WoS1OpenAlex2İncele - Kitap BölümüYalnız künye2025A theoretical framework of renewable energy financing
Soydas, Safak Sonmez
The renewable energy sector is an area that has received increasing attention in recent years and has significant growth potential worldwide. Factors such as limited traditional energy sources, environmental concerns, and climate change encourage using renewable energy sources. In this context, financing renewable energy companies has also gained great importance. Financing is a fundamental requirement for the implementation and expansion of renewable energy projects. However, the fact that renewable energy projects are generally high-cost and have long payback periods makes financing these projects difficult. Therefore, research on the financing of renewable energy companies is extremely important to understand and support the development of the sector. This study intends to ensure a theoretical viewpoint on the financing of renewable energy companies. The study will evaluate the general situation of the renewable energy sector, emphasize the importance of financing, and go over the impression of divergent financing sources on companies' growth strategies. Additionally, recommendations will be presented on the financing challenges faced by renewable energy companies and how these challenges can be overcome.
- Kitap BölümüYalnız künye2025Applying RATMI (Ranking by Alternatives Trace to Median Index) for Ranking Countries Based on Sustainability Performance
Simsek, Ahmet Bahadir; Simsek, Aybala
Today, global problems such as climate change, resource depletion and social inequality motivate the need for tools that can be used to measure the sustainability performance of countries. In this section, a new MCDM approach, RATMI (Ranking by Alternatives Trace to Median Index), is proposed with this motivation. RATMI uses trace and median similarity techniques to provide a balanced and accurate ranking as the median minimises the effect of outliers. In this chapter, the RATMI method is used to assess the sustainability performance of 157 countries for the period 2016-2020 on the basis of economic, social and environmental dimensions. The contributions of this study include the potential to promote RATMI as an effective tool for sustainability assessment of countries, identify role models, and inform policymakers on the development of sustainability strategies at the global level. This practice not only advances the literature on MCDM in sustainability assessments, but also provides a practical framework to guide future policy and research aimed at promoting sustainable development.
AtıfOpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ3Cosmetological potential of the essential oil from the aerial parts of Rubus sanctus Schreb.: Enzymatic inhibition, antibacterial properties, and chemical composition
Yıldırım, Aybeniz; Celep, İnci Kurt; Gül, Abdulkadir
Recently, skin care products and cosmetic preparations with herbal ingredients have attracted considerable interest from the public. Therefore, the cosmetic industry is investigating natural products like essential oils and extracts. This study aimed to determine the anti-aging effects of the essential oil obtained from the aerial parts of Rubus sanctus Schreb. (RsEO), as well as to reveal its chemical composition and investigate its antibacterial activity. The chemical composition of RsEO was determined by using GC-MS. The anti-aging activity of RsEO was evaluated by in vitro studies of anti-collagenase, anti-elastase, anti-tyrosinase, and anti-hyaluronidase activities. The antibacterial potential of RsEO was investigated by the agar-well diffusion method against Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli. RsEO showed significant inhibition against collagenase, elastase, hyaluronidase, and tyrosinase with IC50 values of 80.46, 77.85, 72.71, and 82.71 μg/mL, respectively, and when compared with the positive controls epigallocatechin gallate (IC50: 38.91 μg/mL for collagenase, IC50: 38.91 μg/mL for elastase), tannic acid (IC50: 26.95 μg/mL for hyaluronidase), and kojic acid (IC50: 28.74 μg/mL for tyrosinase), the activities were found to be close. It was determined that the major components of RsEO were pentadecanal (8.88%), dodecanoic acid (7.86%), nonanal (4.32%), and octadecanal (4.08%). RsEO showed moderate antibacterial activity (inhibition zones between 10 and 15 mm) against the tested bacteria compared to ampicillin. This study demonstrated that RsEO is a natural product that has the potential to serve as a promising anti-aging and antibacterial therapeutic agent due to the synergistic effect of its constituent components.
AtıfScopus3WoS3OpenAlex4İncele - MakaleAçık Erişim2025Scopus SJRQ1DSCIMABNet: A novel multi-head attention depthwise separable CNN model for skin cancer detection
Reis, Hatice Catal; Turk, Veysel
Skin cancer is a common type of cancer worldwide. Early diagnosis of skin cancer can reduce the risk of death by increasing treatment success. However, it is challenging for dermatologists or specialists because the symptoms are vague in the early stages and cannot be noticed by the naked eye. This study examines digital diagnostic techniques supported by artificial intelligence, focusing on early skin cancer detection and two methods have been proposed. In the first method, DSCIMABNet deep learning architecture was developed by combining multi-head attention and depthwise separable convolution techniques. This model provides flexibility in learning the dataset's local features, abstract concepts, and long-term relationships. The DSCIMABNet model and modern deep learning models trained on ImageNet are proposed to be combined with the ensemble learning method in the second method. This approach provides a comprehensive feature extraction process that will increase the performance of the classification process with ensemble learning. The proposed approaches are trained and evaluated on the ISIC 2018 dataset with image enhancement applied in preprocessing. In the experimental results, DSCIMABNet achieved 84.28% accuracy, while the proposed hybrid method achieved 99.40% accuracy. Moreover, on the Mendeley dataset (CNN for Melanoma Detection Data), DSCIMABNet achieved 92.58% accuracy, while the hybrid method achieved 99.37% accuracy. This study may significantly contribute to developing new and effective methods for the early diagnosis and treatment of skin cancer.
AtıfScopus26WoS17OpenAlex26İncele - MakaleAçık Erişim2025Scopus SJRQ3Biological activities and phenolic content of endemic Helichrysum artvinense P.H. Davis et Kupicha (Asteraceae)
Acet, Tuba; Özcan, Kadriye; Kalmuk, Nursen Aksu
Species from the Asteraceae family have been extensively utilized in traditional medicine and as food sources for centuries. They also exhibit important biological activities attributed to their diverse array of phytochemical compounds. This research aimed to determine total phenolic and flavonoid contents of ethanol (EtOH) and methanol (MeOH) extracts of endemic Helichrysum artvinense and to reveal its antioxidant, antimicrobial enzyme inhibitory (α-glucosidase, α-amylase, and tyrosinase) and DNA protective activities. In addition, phenolic compound analyses were conducted using high-performance liquid chromatography (HPLC), establishing a correlation with the aforementioned biological activities. Based on the obtained data, the ethanol (EtOH) extract of the plant demonstrated greater prominence in terms of the screened biological activities. This extract was found to contain significant phenolic components, including epicatechin, chlorogenic acid, and luteolin. Consequently, it appears that the plant has the potential to serve as a natural alternative in both food and pharmacological applications. However, further studies to elucidate the mechanisms underlying the observed biological activities would be beneficial for the product development phase.
- Kitap BölümüYalnız künye2025Determination of Criteria for Selection of Candidate Sites for Temporary Debris Storage
Aktaş, Esra; Atmaca, Ediz
Disasters are difficult-to-control situations that have a profound impact on human life and result in significant material and moral losses. Disasters occur suddenly and frequently without warning, resulting in increased losses both during and after the situation. By making plans and taking the necessary precautions, natural and human hazards can be mitigated or avoided. Disaster management plans are being prepared all over the world, including various actions for disaster preparedness, disaster response and post-disaster. The importance and necessity of disaster management plans cannot be ignored in Türkiye, which has frequently encountered disasters from past to present and suffered great loss of life and property. Disaster management is the process by which society, all organizations, and resources work together to reduce or prevent harm before, during, and after a disaster. In this context, the study aimed to determine the criteria required for the selection of candidate areas for temporary debris storage sites, which are very important after the disaster. The importance weights of the criteria obtained through literature research were determined by soliciting expert opinions via the Analytic Hierarchy Process (AHP) method, which is one of the multi-criteria decision-making methods. The criteria with the highest importance weight are listed.
- MakaleYalnız künye2025Scopus SJRQ2Determination of selection-focused physicochemical properties in the local Eğrisap pear (Pyrus communis L.) clone grown in Rize
Kalkisim, Ozgun; Aydin, Mehmet Zahit; Ozdes, Duygu; Duran, Celal
Turkey, located within the Western Asia gene center, is a significant genetic center for many fruit species, including pears. Rize, a province in the Northeastern part of Turkey, is located within the Northeast Anatolia Region, which falls within the genetic center area where pears have undergone evolutionary development. This study aimed to identify promising local Eğrisap pear clone genotypes with superior traits and to introduce them into economic use. For this purpose, Rize province and its districts were surveyed, and fruit and leaf samples were collected from pre-selected Eğrisap pear clone types. These samples were subjected to pomological, morphological, and chemical analysis. The JMP 13 statistical software package was used to compare the Eğrisap pear clone types. According to the research results, the pomological and morphological traits of the clone types varied as follows: fruit weight (99.10–139.54 g), fruit width (54.52–65.41 mm), fruit length (57.58–68.83 mm), fruit stem length (50.75–59.50 mm), fruit stem thickness (2.36–2.91 mm), core width (5.15–7.55 mm), core length (9.73–14.51 mm), flesh firmness (3.61–7.13 lb), seed number (5.30–8.55), leaf width (45.80–60.04 mm), leaf length (64.53–82.37 mm), petiole length (37.04–60.99 mm), petiole thickness (0.83–1.20 mm), and soluble solid content (SSC) (9.10 %-16.0 %). Regarding chemical composition, the pH values of the clone types ranged from (3.78–4.22), titratable acidity (0.22 %-0.47 %), protein content (1.50 %-4.95 %), vitamin C content (0.92–2.28 mg/100 g), ash content (1.16 %-4.30 %), and total sugar content (9.66 %-17.28 %). Mineral element analysis of the local pear varieties revealed that iron content ranged from (0–14.7 µg/g), copper (2.90–9.12 µg/g), manganese (2.9–11.6 µg/g), magnesium (321.7–771.5 mg/g), zinc (0 µg/g), sodium (9.6–39.6 µg/g), potassium (5.43–14.50 µg/g), calcium (50.1–219.7 µg/g), cobalt (0.01–0.31 µg/g), cadmium (0–0.1 µg/g), and nickel (0.08–4.41 µg/g). Among the local Eğrisap pear clones grown in Rize, clone type 53 IYD 01 was identified as having the most superior quality criteria and chemical composition. Consequently, it is recommended that this clone type be introduced to producers for cultivation.
AtıfScopus1İncele - MakaleAçık Erişim2025Scopus SJRQ3Cardiovascular Findings and Effects of Caffeine on Experimental Hypothyroidism
Yuksel, Duygu; Ozmen, Ozlem
Background: Thyroid hormone deficiencies can disrupt organ functions, significantly impacting the cardiovascular system. Recently, the effects of thyroid hormones on the heart have garnered increased attention. However, most studies are conducted on humans using clinical data, while cellular-level and experimental studies remain limited. Objective: This study aimed to investigate the cardiovascular implications of hypothyroidism and evaluate the impact of caffeine on cardiac health in rats induced with hypothyroidism using propylthiouracil (PTU). Methods: The study involved 60 rats divided into six groups. Group 1 served as the untreated control. Group 2 received PTU for two months to induce hypothyroidism. Group 3 received PTU for one month, followed by caffeine for one month. Group 4 received caffeine for two months. Group 5 received both PTU and caffeine simultaneously for two months. Group 6 received PTU for one month, followed by one month under normal conditions. Results: During necropsy, normal thyroid glands were observed in Groups 1, 4, and 6, enlarged thyroids in Group 2, and smaller thyroids in Groups 3 and 5. Microscopic examination revealed varying thyroid histologies: Group 2 showed significant epithelial cell proliferation and absent colloid, while Groups 3, 5, and 6 had altered yet colloid-containing acini. Macroscopic inspection of hearts appeared normal across all groups. However, histopathological examination revealed significant hyperemia and microhemorrhages in Group 2, contrasting with normal findings in other groups. Immunohistochemical analysis indicated reduced cardiac troponin expression in Group 2, while other groups maintained prominent expression. Additionally, Group 2 displayed increased serum TSH levels and decreased T3 and T4 levels. Conclusion: The findings suggest that administering caffeine alongside or after PTU treatment in rats with experimentally induced hypothyroidism may ameliorate thyroid and cardiac irregularities. This study indicates caffeine's potential in mitigating the adverse effects of hypothyroidism on thyroid and heart health.
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