Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(46)
- Kulakaç, Nurşen(21)
- Aydin, Aydanur(16)
- Demir, Selim(16)
- Tuncer, Metin(16)
- Topal, Fevzi(15)
- Turan, Ibrahim(15)
- Yilmaz, Coskun(14)
- Bayrakdaroglu, Serdar(12)
- Koçak, Tevfik(11)
- Aliyazicioglu, Yuksel(10)
- Gulcin, Ilhami(10)
- Ozturk, Samet(10)
- Topal, Meryem(10)
- Ceylan, Halil Ibrahim(9)
- Ceylan, Levent(9)
- Kilinc, Kagan(9)
- Mentese, Ahmet(9)
- Ozdes, Duygu(9)
- Tuncer, Gülsüm Zekiye(9)
- Duran, Celal(8)
- Emirza, Elif Güzide(8)
- Yaman, Serap Ozer(8)
- Yılmaz, Coşkun(8)
- Baltacı, Cemalettin(7)
- Demirağ, Hatice(7)
- Hintistan, Sevilay(7)
- Kaya, Feridun(7)
- Küçük, Murat(7)
- Ürkek, Bayram(7)
- Şengül, Mustafa(7)
- Bayrakdaroğlu, Serdar(6)
- Deger, Orhan(6)
- Genc, Berna(6)
- Gül, Abdulkadir(6)
- Gülçin, Ilhami(6)
- Günen, Mehmet Akif(6)
- Gürsoy, Ayla(6)
- Kurnaz, Muammer(6)
- Supuran, Claudiu T.(6)
Yayınlar
- MakaleAçık Erişim2026Microwave-assisted green synthesis of gold nanoparticles using MAE-derived aqueous Rubuscaesius L. Fruit extract: characterization and UV–Vis spectral stability
Serdar, Gönül; Serdaroğlu, Vildan; Keşi̇r, Melek Koç; Kokoç, Memnune; Terzi̇oğlu, Salih
Gold nanoparticles (AuNPs) were synthesized through a microwave-assisted green route using an MAE-derived aqueous Rubus caesius L. fruit extract as a natural reducing and stabilizing medium. The effects of precursor concentration, extract volume, and microwave power were systematically evaluated within the tested experimental range. The combination of 0.075 mM HAuCl₄0.3 H₂O, 0.4 mL fruit extract, and 180 W microwave irradiation produced the most distinct and symmetric surface plasmon resonance response. FT-IR analysis suggested that oxygen-containing functional groups in the extract may have contributed to Au³⁺ reduction and AuNP surface stabilization. TEM analysis revealed spherical, triangular, and hexagonal nanoparticles with an average core size of 11.6 ± 3.2 nm. DLS showed a hydrodynamic diameter of 71.92 ± 4.12 nm and a polydispersity index of 0.425, while the near-neutral zeta potential indicated limited colloidal stability. UV–Vis monitoring showed that the RC-AuNPs largely retained their spectral characteristics for up to 45 days. The synthesized nanoparticles exhibited a core size comparable to previously reported Rubus-mediated AuNPs. The specific contribution of this study is the use of an MAE-derived aqueous R. caesius L. fruit extract together with the systematic evaluation of key synthesis parameters affecting AuNP formation, optical response, and colloidal behavior.
- MakaleYalnız künye2026The Effect of Parrot Therapy on During Venipuncture Pain in Chronic Patients
Demirağ, Hatice; Tuç, Adile
Objective There are no randomized controlled trial (RCT) in the current literature comparing live, robotic, and visual animal-based therapies. This single-blind randomized controlled trial was conducted to comparatively evaluate the effectiveness of live parrot, robotic parrot, and parrot picture therapies on pain during venipuncture in adults with chronic illness. Methods The study included 240 patients randomized into four groups. Groups interacted with live parrots, robotic parrots, or parrot pictures during venipuncture. The control group received no intervention. Pain levels were assessed before and after the procedure using the "Visual Analog Scale (VAS)." Analysis was performed using Chi-Square test, One-way ANOVA and paired samples t-test. Results There was no difference in pre-procedure pain scores between the groups (p ' .05). After the procedure, the VAS score for the live parrot group was 2.01 ± 1.35, for the robotic parrot group 2.03 ± 1.46, for the parrot picture group 2.08 ± 1.62, and for the control group 4.91 ± 1.88. Again, after the procedure, pain scores in all experimental groups were found to be significantly lower than in the control group (p ' .001). Live parrot therapy was found to be the most effective pet therapy, followed by robotic parrot and parrot picture therapy. The reduction in pain in the live parrot group was statistically more significant than in the picture group. Conclusion The research findings revealed that pet therapy applied during venipuncture, especially live animal interaction, may be a potentially effective, safe, and non-pharmacological method for reducing pain. Robotic animals, on the other hand, can be considered a promising alternative when the use of live animals is not possible. It is recommended that these distraction strategies be considered and integration into routine nursing practices be developed as part of patient-centered care.
- MakaleAçık Erişim2026Game-based and individualized movement training improves physiological and motor outcomes in young adults with autism spectrum disorder: an experimental study from Türkiye
Aydın, Ahmet Serhat; Söyler, Mehmet; Zileli, Raif; Halmatov, Medera; Gürkan, Alper Cenk; Akcan, İbrahim Orkun; Yılmaz, Coşkun
Background: This study aims to examine the effects of game-based and individualized movement training (GBIMT) program on physiological (body weight, body fat percentage, BMI) and motor outcomes (balance, reaction time, motor speed) in young adults diagnosed with autism spectrum disorder (ASD). Methods: An experimental design with pre-test–post-test control groups was used in the study. A total of 20 participants (10 in the experimental group, 10 in the control group) with a mean age of 22.2 ± 4.8 years were monitored for eight weeks. The experimental group participated in GBIMT sessions for 60 min per day, two days per week, while the control group continued their usual educational routines. Body composition (InBody 270 Body Composition Analyzer, model Plus 270, South Korea), balance (TechnoGym, Cesena, Italy), reaction time (BlazePod Ltd., Israel), and motor speed (Computerized Tapping Test, Neurosoft Inc., USA) parameters were used as measurements. Results: Repeated measures ANOVA results indicated a significant reduction in body weight in terms of the experimental group (p = 0.014, η² = 0.289). Large effect sizes were observed for body fat percentage and BMI; however, the group × time interactions were not found to be statistically significant. A significant improvement was observed in the motor speed parameter within the experimental group (p = 0.032, η² = 0.231). Reaction time decreased by 9.8%, although the group × time interaction stayed within the significance limit (p = 0.063). A trend toward improvement was observed in balance parameters; however, no statistically significant difference was found. Conclusion: The findings indicate that GBIMT produced significant improvements in body composition and motor speed after implementing for eight weeks, and also showed a strong tendency to affect reaction time. As a controlled experimental study conducted in Türkiye, this research offers a unique contribution to the literature by demonstrating the effects of game-based and individualized movement programs on both physiological and motor outcomes in individuals with ASD. Trial registration: GameBased and Individualized Movement Training Improves Physiological and Motor Outcomes in Young Adults with Autism Spectrum Disorder An Experimental Study From Türkiye, ClinicalTrials.gov NCT07170891, Date 20,062,025.
- MakaleYalnız künye2026Phenolic Profiling of Laurus nobilis by LC–ESI–MS/MS: In Vitro Bioactivities and In Silico Enzyme Docking
Bak, Funda Erşen; Canbolat Gültekin, Deniz; Akmeşe, Osman; Atalay, Abdurrahman; Turan, İbrahim; Gültekin, Ergün; Demir, Selim; Aliyazicioglu, Yüksel
This study evaluated the branch, leaf, and fruit extracts of Laurus nobilis collected from Artvin in terms of phenolic composition, antioxidant, antimicrobial, and antidiabetic activities and additionally investigated the binding of selected phenolics to α-amylase/α-glucosidase targets through molecular docking. Using LC–ESI–MS/MS analysis, 31 phenolic compounds were quantitatively identified, with epicatechin, luteolin-7-O-glucoside, and rutin predominating particularly in the branches and leaves. Antioxidant capacity was higher in branches and leaves (total phenolic content [TPC]/FRAP/DPPH IC50: branches and leaves, respectively, 95.27–60.84 mg gallic acid equivalent [GAE]/g, 206.16–162.05 mg Trolox equivalent [TE]/g, and 46.95–113.49 µg/mL). Antimicrobial activity was observed within a minimum inhibitory concentration (MIC) range of 1.25–10 mg/mL; leaves exhibited the strongest effect against Bacillus cereus (1.25 mg/mL), whereas fruits were most effective against Candida albicans (1.25 mg/mL). In antidiabetic evaluation, fruits yielded the lowest IC50 values against α-amylase and α-glucosidase (4.31 and 8.97 mg/mL, respectively), suggesting a “composition-over-quantity” effect despite low total phenolic content. Docking results supported high binding affinities of rutin (α-glucosidase −9.3 kcal/mol; α-amylase −8.1 kcal/mol) and luteolin (−8.6 kcal/mol for both enzymes). Overall, although branches and leaves exhibited strong antioxidant profiles, fruits showed more pronounced inhibitory effects on digestive enzymes; therefore, fractionation studies and in vivo/kinetic validations are recommended.
- MakaleAçık Erişim2026Examination of Post-Traumatic Stress Reaction, Quality of Life, and Loneliness Levels in Adolescents Who Experienced an Earthquake
Akay, Gamze; Koç, Elif Simay; Oğuzhan, Hatice
The aim of this study is to investigate the relationship between post-traumatic stress, quality of life, and loneliness levels in adolescents following the earthquakes centered in Kahramanmaraş. The research, designed as descriptive and correlational, was conducted with 701 children aged 13–18 who experienced the earthquake in Kahramanmaraş. Data were collected through a Demographic Information Form, the Child Post-Traumatic Stress Reaction Index, the Pediatric Quality of Life Inventory, and the UCLA Loneliness Scale-Short Form. Ethical principles were adhered to throughout the study. Female adolescents were found to have higher levels of post-traumatic stress (t = 3.508, p < 0.001) and lower quality of life (t = 4.223, p < 0.001). The adolescents exhibited severe levels of post-traumatic stress (55.25 ± 13.80). It was determined that the mother’s education level (F = 4.423, p = 0.002), the father’s occupation (F = 2.859, p = 0.036), and perceived income level (F = 5.912, p = 0.003) significantly influenced adolescents’ loneliness levels. The father’s occupation (F = 3.403, p = 0.017) was found to have a significant effect on post-traumatic stress levels, and perceived income level (F = 4.753, p = 0.009) had a significant effect on quality of life. A moderate negative correlation was found between post-traumatic stress levels and quality of life (r = −0.474, p < 0.001), and a weak positive correlation was observed between post-traumatic stress and loneliness levels (r = 0.215, p < 0.001). A weak negative correlation was also found between quality of life and loneliness levels (r = −0.284, p < 0.001). A moderate negative correlation was found between adolescents’ post-traumatic stress levels and quality of life, while a weak positive correlation was observed between post-traumatic stress levels and loneliness. It is recommended to provide psychological support and guidance services aimed at reducing post-traumatic stress and loneliness levels in adolescents.
- MakaleYalnız künye2026An AI-Supported Virtual Patient Application Using a Structured Prompting Framework to Develop Mental Status Examination Skills in Psychiatric Nursing Internship Students: An Interventional Mixed-Methods Study
Tuncer, Gülsüm Zekiye; Çetinkaya Duman, Zekiye; Kilinçkaya, Başak
The aim of this study is to evaluate the effect of an artificial intelligence (AI)-powered virtual patient application (ChatGPT) on the development of Mental Status Examination (MSE) skills in psychiatric nursing internship students and to explore how this process is reflected in their experiences. This study employed a sequential explanatory mixed-method design, consisting of a quantitative pre/post-test phase followed by a qualitative phase. In the quantitative phase, the MSE Competency Assessment scores of 27 undergraduate psychiatric nursing internship students were evaluated using a pre-test/post-test model. In the qualitative phase, in-depth individual interviews were conducted with 18 volunteer students. As part of the intervention, students participated in the “AI-Supported Virtual Patient Intervention: Structured Prompting Framework”. The quantitative findings of the study revealed that the mean MSE Competency Assessment scores increased from 42.00 ± 6.43 in the pre-test to 49.57 ± 3.44 in the post-test (Z = −6.266, p < 0.001). Thematic analysis of the qualitative data yielded five main themes: Skill Development, Learning Experience, Impact of AI, Debriefing, and Limitations. Students reported that the application enhanced their MSE examination and communication skills; they also described a unique learning experience through AI, highlighted the importance of guided support.
- MakaleAçık Erişim2026Nurse-Led Mobile App Effect on Quality of Life in Breast Cancer Patients After Surgery: Nonrandomized Controlled Prospective Cohort Study (Step 3)
Aydin, Aydanur; Gürsoy, Ayla
Background: – Following surgery, women with breast cancer (BC) frequently experience emotional and physiological negative consequences. Objective: – To evaluate the effect of a nurse-led mobile app (NL-Mapp) intervention on quality of life (QoL) in patients after surgery for BC. Methods: – This single-center, 12-month, nonrandomized controlled trial, with 2 parallel groups, represents the final stage of 3-step research. In this study, women were assigned to either the intervention (n = 45) or control (n = 45) group. The intervention group participated in the NL-Mapp, whereas participants in the control group received standard care. The main outcomes were measured using the Functional Assessment of Cancer Therapy—Breast at 3 time points (baseline and 1 and 12 months after the intervention). Clinical Trial number: NCT06505538 Results: – The intervention participants reported significant improvement in physical well-being, emotional well-being, and the BC-specific subscale compared with the control group at the 1-month postsurgery mark. Equally noteworthy, at the 1-year follow-up, consistent improvements were observed across all QoL subscale scores for the intervention group, except for the BC-specific subscale for additional concerns. Conclusion: – Our study revealed a notable enhancement in the QoL among postoperative women with BC who utilized the NL-Mapp. This program emerges as an effective intervention for providing short-term and longer-term supportive care to women affected by BC, leading to tangible improvements in their QoL. Implication for Nursing: – The study’s findings offer valuable evidence supporting the integration of mobile health services into clinical and transitional nursing care.
- MakaleYalnız künye2026Changes in BMI, lipid profile, disease perception, and quality of life among myocardial infarction patients participating in a 12-week green walking: A quasi-experimental study
Cin, Aynur; Hintistan, Sevilay
Objective This study assessed the 12-week intervention of green walking on BMI, blood lipids, disease perception, and quality of life among myocardial infarction patients. Methods In a quasi-experimental design, 60 participants (28 men, 32 women; aged 36–77 years) were assigned to intervention (green walk) or control (routine care) groups based on geographic convenience. The green walking group performed high-intensity interval walking for 50 min three times a week in a natural setting for 12 weeks. Adherence was monitored via attendance logs, with a mean of 91.7 % (SD 7.1 %). Primary outcomes included BMI and lipid profiles, while secondary outcomes included perceived illness and quality of life, assessed through validated questionnaires. A mixed-design model incorporating time-group interaction was used for analysis. Data were analyzed using mixed-design ANOVA, repeated-measures ANOVA, paired t-tests, Friedman tests, and Wilcoxon tests. Results The green walk group showed improvements in several measures including a reduction in BMI and positive changes in lipid profiles and disease perception scores with enhanced quality of life for both groups. The mean differences between groups for weight, BMI, and concerns over medication were not significant. No severe adverse events were recorded during the entire 12-week program. Conclusions Participation in the green walking program for 12 weeks is associated with favorable trends in BMI, lipid levels, disease perception, and quality of life among myocardial infarction patients which structured green walking can be an aid toward improving well-being during cardiac rehabilitation; however further randomized controlled studies will substantive such an association.
- MakaleAçık Erişim2026Antibacterial efficacy of pyrolysis-derived plant fractions against resistant pathogens: a comparative evaluation using nutrient and Müller–Hinton agar
Demirel, Maruf Hurşit; Gül, Abdulkadir; Aydoğmuş, Ercan; Özgen, İnanç; Arslanoğlu, Hasan
BACKGROUND: This study investigates the antibacterial potential of pyrolysis-derived extracts from rosehip fruit (RF), orange peel (OP), corn silk (CS), spurge root (ER) and mullein leaf (ML) against antibiotic-resistant pathogens using two different culture media. Bioactive compounds were obtained via a PID-controlled pyrolysis system, and antibacterial activity was evaluated to clarify both extract efficacy and medium-dependent effects on bacterial growth and diffusion. RESULTS: Antibacterial activities were assessed using the agar well diffusion method, with ampicillin as a positive control, against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis. A key novelty of this work is the comparative evaluation of extract performance on nutrient agar (NA) and Müller–Hinton agar (MHA). Among all samples, the ML extract exhibited the strongest antibacterial activity across all tested strains, producing inhibition zones of 18.85 mm against E. coli and 17.15 mm against E. faecalis on NA, compared with 13.05 mm and 13.60 mm on MHA, respectively. CS and ER extracts showed moderate antibacterial effects, with consistently higher inhibition zones on NA than on MHA. Ampicillin generated substantially larger inhibition zones on NA (33.35 mm for E. coli and 34.45 mm for P. aeruginosa) compared with MHA (13.80 and 27.70 mm, respectively), confirming the strong influence of culture medium composition on measurable antibacterial activity. CONCLUSION: These results indicate that both plant extracts and ampicillin exhibit higher antibacterial activity on NA than on MHA. The pronounced efficacy of the ML extract highlights pyrolysis-derived plant fractions as promising natural antimicrobials and emphasizes the critical importance of culture medium selection.
- MakaleAçık Erişim2026Green-synthesis of iron nanoparticles using wild cherry laurel (Prunus laurocerasus L.) fruit extract and their patulin and HMF adsorption capacities along with biological activities
Kobya, Havva Nur; Gül, Esra; Karpuz, Ömer; Baltacı, Cemalettin
In this study, iron nanoparticles (YBFeNPs) were green-synthesized using the aqueous extract (YB-E) of wild cherry laurel (Prunus laurocerasus L.) fruit to evaluate their potential applications in food safety. The synthesized YBFeNPs were investigated through Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and energy-dispersive X-ray spectroscopy analyses. YBFeNPs showed higher total phenolic content, total flavonoid content, and total antioxidant capacity compared to the original extract, suggesting that plant metabolites enhance NP bioactivity. Antioxidant capacity was further validated by DPPH, ABTS, and FRAP assays, which demonstrated strong radical scavenging and reducing power. The antibacterial activity of YBFeNPs was assessed against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis, revealing concentration-dependent effects with the highest inhibition zone of 14.5 ± 0.4 mm for E. coli. The chemical composition of the YB-E extract was analyzed using liquid chromatography-tandem mass spectrometry, identifying quinic acid, a polyol, and phenolic compounds such as chlorogenic acid (1.45 mg/g) and naringenin (0.02 mg/g). Additionally, the adsorption capacities of YBFeNPs were investigated against patulin and hydroxymethylfurfural (HMF), toxic compounds posing significant threats to food safety. The NPs demonstrated effective adsorption of both patulin and HMF, achieving maximum adsorption rates of 61.05% and 46.12%, respectively, at a concentration of 5.0 g/L after 240 min.
- MakaleAçık Erişim2026Layered Polymeric Carbon Nitride as a Green Support for Cellulase Immobilization: Improved Stability, Activity, and Reusability
Gulesci, Nuri; Altan, Orhan; Toprak, Ali; Yalçın, M. Serkan; Bilgin, Ramazan; Yildirim, Deniz
Polymeric carbon nitride (PCN) has attracted considerable attention in recent years due to its layered structure and donor groups such as terminal amines and triazine units. In this study, PCN was synthesized from melamine and employed for the first time as a support material for the immobilization of cellulase, a key enzyme used in numerous industrial applications. Transmission electron microscopy (TEM) analysis revealed that ranged from 219 to 375 nm in size, thereby confirming their nanoscale layered morphology. Cellulase from Aspergillus sp. was immobilized onto PCN using three methods. In the first approach, cellulase was adsorbed onto PCN to form PCN@cellulase. In the second method, PCN@cellulase was cross-linked with glutaraldehyde (PCN@cellulase/Glu). Finally, the primary amino group of PCN was modified with glutaraldehyde, and the cellulase was immobilized onto this support via covalent attachment (PCN/Glu@cellulase). Each cellulase preparation was assessed for its optimal pH, temperature conditions, thermal stability, and enzyme kinetics. The optimal pH was 5.5 for all cellulase preparations, while the optimal temperature was 45 °C for free cellulase and 55 °C for all immobilized cellulase preparations. Thermal stability of PCN@cellulase, PCN@cellulase/Glu, and PCN/Glu@cellulase increased by 2.1-, 2.7-, and 3.7-fold, respectively, compared to the free cellulase. PCN/Glu@cellulase showed a 1.4-fold higher catalytic efficiency than the free cellulase and retained 80% of its initial activity after 10 reuses. This work highlights PCN as a green, metal-free, and easy-to-prepare support for enzyme immobilization, thereby opening new possibilities for sustainable bioprocessing applications.
- MakaleYalnız künye2026Evaluation of family-centered care from the perspectives of pediatric nurses, nursing students and parents: A mixed-methods study
Çolak, Bahar; Güner, Yasemin; Goger, Berrin; Kahriman, İlknur; Dal Sevim, Şura
Introduction This study aimed to evaluate family-centered care (FCC) practices in pediatric units from the perspectives of pediatric nurses, nursing students, and parents. Methods A convergent parallel mixed-methods design was employed. Quantitative data were collected using a cross-sectional design, while qualitative data were obtained through a case study approach. The sample consisted of 338 parents, 221 nursing students, and 10 pediatric nurses. Parents completed the FCC Assessment Scale and the PedsQL Healthcare Satisfaction Module, nursing students completed the Caring Behaviors Inventory, and pediatric nurses participated in semi-structured interviews. Results Parents reported high scores in the FCC dimensions of “support,” “collaboration,” and “respect,” which significantly predicted parental satisfaction. The “support” dimension was the strongest predictor of satisfaction with information, family participation, and technical skills. Nursing students rated pediatric nurses' caring behaviors highly. Qualitative analysis identified five major themes: (1) Perception of FCC, (2) Role of the Nurse, (3) Role of the Physician, (4) Benefits of FCC, and (5) Barriers to FCC. These themes highlighted the importance of family participation, the nurse's leadership role, gaps in physician communication, the multifaceted benefits of FCC at the child, family, and system levels, and barriers including workload, physical environment limitations, and family-related challenges. Conclusion Perceived FCC practices significantly predicted parental satisfaction. However, improvements are needed in information sharing, family participation, and physical environment conditions. Implications to practice These findings provide valuable insights for developing educational, clinical, and policy strategies to strengthen the implementation of FCC in pediatric nursing practice.
- MakaleYalnız künye2026Spatial heterogeneity of microscopically detected Nosema spp. infection in honeybees: Climate-associated patterns in the Eastern Black Sea Region of Türkiye
Tosun, Onur; Bekircan, Çağrı; Kurnaz, Muammer
Nosemosis has emerged as the predominant microsporidian infection of honeybees (Apis mellifera L.) in many regions, including Türkiye, yet the climatic drivers of its epidemiology remain insufficiently quantified. This study assessed the effects of temperature and relative humidity on nosemosis prevalence across seven provinces in the climatically diverse Eastern Black Sea region. A dataset of 2688 colony-level observations was analyzed using generalized linear models, mixed-effects models, beta regression, generalized additive models, and spatial autocorrelation. Both temperature and humidity were consistently significant predictors (p < .001). Quadratic temperature terms and nonlinear GAM smooths were consistent with a thermal performance pattern, with infection peaking at intermediate ranges. Humidity exerted threshold-like effects, with disproportionately higher prevalence at upper quantiles. Province-level random effects accounted for ∼18% of variance, underscoring spatial heterogeneity, while elevation was not significant once climatic variables were included. Exploratory spatial analysis (Global Moran's I = −0.476, p = 0.043) tentatively suggested dispersion rather than clustering; however, given the very small number of spatial units (n = 7), this result should be regarded as hypothesis-generating only. The beta mixed-effects model achieved moderate predictive accuracy under cross-validation (RMSE ≈ 0.109). Collectively, these findings indicate that nosemosis prevalence in the region is strongly associated with climatic variability, exhibits nonlinear and threshold-like responses, and shows pronounced spatial heterogeneity. We emphasize that these are statistical associations and that unmeasured factors (e.g., colony strength, nutrition, pesticide exposure, management practices, and co-infections) likely contribute to the unexplained variance. By integrating hierarchical, nonlinear, and spatial approaches, this study establishes a climate-associated epidemiological assessment of nosemosis risk in A. mellifera and highlights the importance of localized climatic suitability under ongoing climate change.
- MakaleAçık Erişim2026A Deep Learning–Based Framework for Automatic Determination of Developmental Dysplasia of the Hip from Graf Angles
Taşolar, Sevgi; Günen, Mehmet Akif; Sığırcı, Ahmet; Taşolar, Hakan
Developmental dysplasia of the hip (DDH) is a common neonatal condition that necessitates early diagnosis to ensure effective treatment. The traditional Graf method, while widely used for evaluating infant hips via ultrasound, is limited by operator dependency and measurement variability. This research has proposed a framework using deep learning network, morphological operation and local maxima method to diagnose DDH in newborns using ultrasound images. The method utilizes DeepLabv3 + for image segmentation, evaluating multiple backbone architectures (ResNet50, InceptionResNetV2, MobilenetV2, and Xception) to identify the region of interest accurately. Local maxima method was used to determine the extremum points of the line defining the Graf angles. Denoising filters, including mean, median, and Wiener, are applied to determine local maxima points accurately. The evaluation comprises two stages: first, assessing the performance of DeepLabv3 + backbones in producing masks for Graf angles determination, and second, comparing the angles obtained through proposed framework with those determined by expert radiologists. Comparative analysis demonstrates that MobileNetV2 (94.64 accuracy, 86.99 Cohen’s kappa, 94.31 F-score) surpasses other models in segmentation accuracy and measurement reliability. This conclusion is backed by key performance metrics such as accuracy, IoU, PSNR, F-score, SSIM, Cohen’s kappa, as well as by the intraclass correlation coefficient and Bland–Altman analyses. The proposed framework shows considerable promise in automating hip ultrasound analysis for DDH diagnosis, minimizing operator dependency while enhancing measurement consistency.
- MakaleYayıncıda açık erişim2026Production and Multi-Criteria Evaluation of Healthy White Cheese Snacks Using Microwave-Vacuum Drying
Ayrancı, Vasıf Kubilay; Mzoughi, Mondher; Salum, Pelin; Zemzemoğlu, Tuba Eda Arpa; Erbay, Zafer
Microwave-assisted vacuum drying (MVD) is an emerging technology suitable for producing healthy snack foods, such as cheese snacks. This study aimed to produce a low-fat, low-salt, crunchy cheese snack using MVD. Low-fat, low-salt cheese slices were dried under seven different combinations of microwave power (5%–15%), vacuum level (220–300 Torr), and drying time (6.5–11 min), selected through preliminary trials. The resulting snacks were characterized by their physical properties and volatile compound profile. The results revealed significant differences in moisture content, water activity, bulk density, and volumetric/surface/cross-sectional expansion among the samples. Samples produced under high vacuum and long process time conditions exhibited the most favorable overall characteristics, including the lowest moisture, water activity, and density, alongside the highest volume expansion. These samples also showed a darker color and a superior crispy texture (higher fracturability with lower hardness, springiness, and chewiness). Twelve volatile compounds, with a profile limited by the low-fat content of the cheese, were detected. The TOPSIS analysis identified the sample produced under high vacuum conditions (dried at 10% power, 220 Torr, 10 min) as optimal. Practical Applications: This study provides a roadmap for producing crunchy, low-fat, and low-salt cheese snacks using microwave vacuum drying. For food manufacturers, the identified optimal conditions offer a process guideline to develop a healthier snack alternative with an appealing texture and color. The systematic TOPSIS-based evaluation method can be adopted for quality control and product development decisions. For consumers, the resulting product aligns with growing demand for nutritious, reduced-sodium convenience foods.
- MakaleAçık Erişim2026Effect of Breastfeeding Education Delivered Through Motivational Interviewing on Breastfeeding Motivation, Self-Efficacy, and Maternal Bonding in Mothers Giving Vaginal Birth: Randomized, Controlled Trial
Palancı Ay, Özge; Aktaş, Songül
Objectives: This study examined the effect of breastfeeding education using the motivational interviewing technique on breastfeeding motivation, self-efficacy, and mother–infant bonding in mothers who gave birth vaginally. Methods: This randomized, controlled trial included 80 primiparous mothers. The experimental group received breastfeeding education with the motivational interviewing technique at four time points. Data were collected using Maternal Descriptive Information Form (MDIF), the Primiparous Breastfeeding Motivation Scale (PBMS), the Breastfeeding Self-Efficacy Scale (BSES), the Mother–Infant Bonding Scale (MIBS), and the Motivational Interviewing Importance and Confidence-Efficacy Rating Scale. Data were collected at three time points: immediately before training (pretest), 15 days following completion of the training (post-test), and 4 weeks thereafter (follow-up). Data were evaluated using Student’s t test, Mann–Whitney U test, analysis of variance, Friedman variance test, and intention-to-treat analysis. Results: In the post-test and follow-up evaluations, the experimental group had significantly higher mean scores than the control group in the “Value ascribed to breastfeeding” (p < 0.001 and p = 0.004, respectively) and “Midwife support” (p < 0.001 and p = 0.003, respectively) subdimensions of the PBMS as well as in “Motivational interviewing importance” (p < 0.005) and “Confidence-efficacy rating scale” (p < 0.001). During the follow-up period, the experimental group also showed significantly higher scores in the “Self-efficacy” subdimension (p < 0.001) and total mean scores of the BSES (p = 0.033) and MIBS (p = 0.002) than the control group. However, the “Expectation of success” subdimension score of the PBMS was not significant (p > 0.05). Conclusion: Breastfeeding education using the motivational interviewing technique enhances breastfeeding motivation (including values ascribed to breastfeeding, self-efficacy, and midwife support), breastfeeding self-efficacy, mother–infant bonding, and the importance and confidence-efficacy levels in breastfeeding. © The Author(s) 2026. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
- MakaleYalnız künye20265-Hydroxymethylfurfural and furfural levels in non-alcoholic beverages: a survey of product types
Arslan Burnaz, Nesibe; Baltacı, Cemalettin; İlyasoğlu, Huri
Toxic furanic compounds such as 5-hydroxymethylfurfural (HMF) and 2-furfural (F) can form during the processing and storage of non-alcoholic beverages (NABs). This study aimed to determine the levels of HMF and F in a wide range of NAB categories, including fruit juices and nectars, carbonated soft drinks, non-carbonated soft drinks, energy drinks, and coffee with milk drinks. The levels of HMF and F were determined using a validated analytical method. The HMF and F levels of the studied samples varied depending on the type of product. The coffee with milk drinks exhibited the highest levels, while the carbonated soft drinks exhibited the lowest. Notably, the HMF levels of most of the coffee with milk drinks exceeded 10 mg L−1. The findings provide novel insights into the presence of furanic compounds in NABs and emphasise the importance of raising consumer awareness regarding potential dietary exposure to furanic compounds, particularly from coffee drinks.
- MakaleAçık Erişim2026Psychological distress and food neophobia: the mediating role of food choice motives among university students
Kocak, Tevfik; Kocyigit, Emine; Ozbek, Yagmur Demirel
Background: Food neophobia, defined as the reluctance to try unfamiliar foods, reduces dietary diversity and quality in young adults. University students, often subjected to psychological discomfort including sadness, anxiety, and stress, may be especially susceptible to restrictive eating behaviors. This study examined the link be-tween psychological distress and food neophobia, focusing on the mediating role of food choice motives in Turkish students. Methods: A cross-sectional online survey was conducted among 801 Turkish university students (232 males and 569 females). The data collection included the Food Neophobia Scale (FNS), the Depression, Anxiety, and Stress Scale (DASS-21), and the Food Choice Questionnaire (FCQ). The body mass in-dex was calculated using self-reported anthropometric measurements. Statistical analyses comprised correlations, multivariable linear regression, and mediation mod-eling using Hayes’ PROCESS macro with 5000 bootstrap samples. Results: Food neophobia was positively associated with all DASS-21 subscales (p < 0.001). Regression analyses identified depression (p < 0.001), stress (p = 0.001), convenience (p = 0.001), and ethical concern (p < 0.001) as significant positive predictors, whereas natural con-tent showed a negative association (p = 0.046). Mediation analyses indicated that food choice motives partially explained the associations between psychological distress and food neophobia. Convenience and ethical concern consistently acted as mediators of risk, while natural content demonstrated a more complex role. Conclusions: Food neophobia among university students is influenced by both psychological distress and food choice motives. Depression and stress exert stronger effects than anxiety, with convenience and ethical concern functioning as consistent mediators.
- MakaleYalnız künye2026The Effect of Jet Lidocaine on Pain and Anxiety During Peripheral Venous Access: A Systematic Review and Meta-Analysis
Aydin, Esra; Uzun, Sevda
Objective: – The aim of this study was to determine the effect of jet lidocaine on pain and anxiety during peripheral venous access. Methods: – A comprehensive literature search was conducted in PubMed, Web of Science, EBSCOhost, Google Scholar, and the YÖK Thesis Center without year limitation. Five randomized controlled trials that met the inclusion criteria were included in the analysis. Data extraction and methodological quality assessment were performed using the Joanna Briggs Institute (JBI) Critical Appraisal Tools, and study selection was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The findings were synthesized using meta-analysis and narrative synthesis. Results: – The pooled analysis demonstrated that jet lidocaine significantly reduced anxiety related to peripheral venous access (standardized mean difference: −1.031; 95% confidence interval: −1.653 to −0.409; Z = −3.249; P =.001; I2 = 89.98%). However, its effect on pain was not statistically significant (standardized mean difference: −0.817; 95% confidence interval: −1.817 to 0.182; Z = −1.602; P =.109; I2 = 96.57%). Conclusion: – Jet lidocaine may be an effective option for reducing anxiety during peripheral venous access; however, its effect on pain was not statistically significant. Further high-quality randomized controlled trials with standardized protocols and larger sample sizes are needed to clarify its analgesic effectiveness and clinical outcomes.
- MakaleAçık Erişim2026Acute effects of inspiratory muscle warm-up on muscular performance and pulmonary function in natural male bodybuilders
Ceylan, Tülay; Ceylan, Levent; Yılmaz, Coşkun; Badau, Adela; Küçük, Hamza
Background: Inspiratory muscle warm-up (IWU) has been hypothesized to enhance athletic performance by pre-activating respiratory muscles; however, evidence in professional natural male bodybuilders is scarce. The present study investigated the acute effects of IWU on One-Repetition maximum (1RM) bench press performance and pulmonary function. Methods: The present randomized controlled experimental study comprised 20 male athletes with an average training experience of 3.21 ± 1.44 years, who trained for more than 5 h per week and had participated in national or international competitions. At the commencement of the study, all participants underwent a series of pulmonary function tests (PFTs), measurements of maximal inspiratory and expiratory pressures (MIP and MEP), and a 1RM test. Following the initial assessments, which were conducted seventy-two hours prior, participants were randomly assigned to either the IWU group (n = 10) or the control (CON) group (n = 10). While the IWU group performed both inspiratory muscle warm-up and standard exercise warm-up, the CON group performed only the standard warm-up. Subsequent to the execution of the warm-up protocols, both groups were subjected to re-evaluation through the means of the 1RM test and respiratory parameter measurements. Results: The IWU group demonstrated a 5.96% greater enhancement in 1RM performance in comparison to the control group (p < 0.001). Furthermore, significant increases were observed in FVC, FEV1, and FEV1/FVC following IWU, with improvements of 2.57%, 2.44%, and 2.65%, respectively (p < 0.001). Furthermore, an additional 2.39% enhancement in MEP was identified in favour of the IWU group (p = 0.008). The alterations in MIP and PEF exhibited by the two groups were analogous, with no statistically significant disparities observed (p > 0.05). Conclusions: The present study has demonstrated that IWU has the capacity to rapidly enhance maximal strength and respiratory function in professional bodybuilders. Consequently, IWU can be advocated as an efficacious warm-up technique to augment exercise performance in bodybuilding athletes. Trial registration: This trial was registered at ClinicalTrials.gov under the title “Acute effects of inspiratory muscle warmup on muscular performance and pulmonary function in natural bodybuilders’’. ClinicalTrials.gov NCT07390149, Date 18012026. (Retrospectively)