Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(46)
- Kulakaç, Nurşen(21)
- Aydin, Aydanur(16)
- Demir, Selim(16)
- Tuncer, Metin(16)
- Topal, Fevzi(15)
- Turan, Ibrahim(15)
- Yilmaz, Coskun(14)
- Bayrakdaroglu, Serdar(12)
- Koçak, Tevfik(11)
- Aliyazicioglu, Yuksel(10)
- Gulcin, Ilhami(10)
- Ozturk, Samet(10)
- Topal, Meryem(10)
- Ceylan, Halil Ibrahim(9)
- Ceylan, Levent(9)
- Kilinc, Kagan(9)
- Mentese, Ahmet(9)
- Ozdes, Duygu(9)
- Tuncer, Gülsüm Zekiye(9)
- Duran, Celal(8)
- Emirza, Elif Güzide(8)
- Yaman, Serap Ozer(8)
- Yılmaz, Coşkun(8)
- Baltacı, Cemalettin(7)
- Demirağ, Hatice(7)
- Hintistan, Sevilay(7)
- Kaya, Feridun(7)
- Küçük, Murat(7)
- Ürkek, Bayram(7)
- Şengül, Mustafa(7)
- Bayrakdaroğlu, Serdar(6)
- Deger, Orhan(6)
- Genc, Berna(6)
- Gül, Abdulkadir(6)
- Gülçin, Ilhami(6)
- Günen, Mehmet Akif(6)
- Gürsoy, Ayla(6)
- Kurnaz, Muammer(6)
- Supuran, Claudiu T.(6)
Yayınlar
- MakaleYayıncıda açık erişim2026Scopus SJRQ1Chitosan-Based Colloidal Delivery Systems as Natural Carriers for Propolis: Physicochemical Characterization and Application in Walnut Sausages
Mesci Dindar, Esra; Arserim-Uçar, Dılhun Keriman; Ayna, Adnan
In this study, a chitosan-based colloidal delivery systems (CDs) was developed as a natural delivery system for phenolic compounds from propolis extracts obtained via accelerated solvent extraction (ASE) and evaluated for improving the functional properties of walnut sausages. ASE propolis extract was incorporated into a chitosan (C)-based colloidal delivery system formulated with varying concentrations of diacetyl tartaric acid ester of mono- and diglycerides (DATEM) and lecithin (L). The formulation containing 2.5% chitosan, 12% DATEM and propolis, with a particle size of 265.9 nm and a ζ-potential of +40.8 mV, was selected for further characterization and food applications. The phenolic encapsulation of CDs depended on the structural characteristics of individual phenolic compounds, with chrysin (70.51%), vanillin (65.12%), and benzoic acid (51.26%) exhibiting the highest encapsulation; CD-treated walnut sausages decreased the lipid oxidation and improved the storage stability of the walnut sausages during storage. These findings indicate that the chitosan-based colloidal delivery system is a promising carrier for improving the encapsulation of propolis phenolics in walnut sausages.
- MakaleYalnız künye2026Scopus SJRQ2LC–MS/MS Phenolic Profiling and Antioxidant, Antimicrobial, and Antidiabetic Activities of Caucasian Propolis
Gültekin, Deniz Canbolat; Turan, İbrahim; Akmeşe, Osman; Gültekin, Ergün; Demir, Selim; Aliyazicioglu, Yüksel
Propolis is a natural bee product rich in phenolic and flavonoid compounds and is well known for its remarkable biological properties. In this study, the phenolic compositions of propolis samples collected from various localities in the Caucasus region of Türkiye were characterized using LC–MS/MS, and their antioxidant, antidiabetic, and antibacterial activities were also evaluated. LC–MS/MS analyses identified caffeic acid, ferulic acid, and p-coumaric acid as the major phenolic acid compounds, while pinocembrin, chrysin, and galangin were determined as the major flavonoid constituents. Overall, these findings indicate that the antioxidant capacity of propolis samples obtained from different regions may be particularly associated with these key phenolic and flavonoid compounds. Consistent with this composition, total phenolic and flavonoid contents ranged from 34.72 to 120.54 mg GAE/g and 6.88 to 47.19 mg QE/g, respectively. The extracts exhibited a relatively high antioxidant capacity, with FRAP values between 60.47 and 311.87 mg TE/g and DPPH IC50 values ranging from 215.80 to 37.96 µg/mL. Regarding antidiabetic activity, the IC50 values for α-amylase and α-glucosidase inhibition were determined as 5.86–3.47 and 12.22–5.02 mg/mL, respectively, indicating a pronounced antidiabetic potential. Antimicrobial analyses revealed activity against E. faecalis, B. cereus, E. coli, K. pneumoniae, and C. albicans. Overall, this study provides a comprehensive LC–MS/MS-based phenolic profile of Caucasian propolis and demonstrates its antioxidant properties together with its antidiabetic potential.
AtıfScopus2WoS2OpenAlex4İncele - Derleme MakaleYalnız künye2026Scopus SJRQ1Immunosuppressant adherence levels in kidney transplant recipients measured by electronic monitoring devices: A systematic review and meta-analysis
Tuncer, Metin; Yalcinkaya, Turgay; Erol, Ahmet; Özalp, Cemal
Background: Kidney transplantation improves survival and quality of life in patients with end-stage renal disease; however, long-term graft success depends on adherence to immunosuppressive therapy. Objective: To quantify adherence levels among kidney transplant recipients using electronic monitoring devices. Methods: PubMed, Web of Science, Scopus, and the Cochrane Library were systematically searched for studies published between 2000 and 2025. A random-effects meta-analysis was conducted including studies that assessed adherence using electronic monitoring devices. Results: Seven studies with a total of 1025 kidney transplant recipients were included. The pooled mean adherence measured using electronic monitoring devices was 94.39%. In studies with monitoring durations of three months or longer, adherence decreased to 90.50%. Substantial heterogeneity was observed across studies. Conclusion: Although electronically measured adherence appears generally high, its decline over longer monitoring periods indicates that adherence is dynamic and may decrease over time. However, these estimates should be interpreted cautiously because electronic monitoring devices cannot confirm actual medication ingestion. Furthermore, intentionally non-adherent patients may be less likely to participate in or remain engaged with electronic monitoring studies and may therefore be underrepresented, potentially leading to an overestimation of true adherence. Even modest reductions in adherence may carry important clinical consequences, underscoring the need for sustained monitoring.
- Derleme MakaleAçık Erişim2026Scopus SJRQ1Artificial-intelligence–based developmental screening for pre-school children (ages 3–6): a scoping review of deployed tools, clinical validity, equity, and implementation in guidance-center settings
Arslan, Adem; Gül, Fatih
Background – Early identification of neurodevelopmental conditions during the pre-school years (ages 3–6) is critical for timely intervention, yet traditional questionnaire-based screeners suffer from low positive predictive value, late detection, and inequitable access. Artificial intelligence (AI) and machine-learning (ML) methods promise more objective, scalable identification, and two devices (Cognoa Canvas Dx, 2021; EarliPoint Evaluation, 2023) are already US Food and Drug Administration (FDA)-authorized. Recent reviews summarize the technical literature, but few address how deployed tools perform on clinical validity, equity, and real-world implementation, particularly outside high-income, English-speaking settings. Methods – Following Joanna Briggs Institute methodology and the PRISMA extension for scoping reviews (PRISMA-ScR), we searched seven databases (1 January 2020–15 June 2026) and charted primary validation studies of AI/ML developmental-screening tools for children aged 72 months or younger. We mapped tools by modality, diagnostic performance, regulatory status, geographic origin, and, as a structured analytic axis, demographic subgroup (equity) reporting and deployment readiness. Results – Sixteen primary AI-tool studies met inclusion, spanning eight modality classes (eye-tracking, multimodal questionnaire-plus-video, computer-vision home/clinical video, tablet/smartphone digital phenotyping, voice/acoustic ML, electronic-health-record risk prediction, questionnaire-based ML, and wearable sensors) and eight countries (USA, South Korea, Australia, Switzerland, France, Israel, China, Vietnam). Reported sensitivities ranged from approximately 75 to 99.2% and specificities from 78.9 to 95.5%. Only one tool demonstrated stable performance across sex, race, and ethnicity; subgroup-stratified validation was otherwise near-absent. No CE-marked autism-specific screening device was identified. Conclusions – The evidence base has broadened in modality and geography but remains autism-concentrated and equity-blind, with a wide gap between analytic accuracy and primary-care deployment. We propose equity validation, deployment-readiness reporting, and an implementation pathway for low-resource guidance-center settings as priorities.
- MakaleYayıncıda açık erişim2026Scopus SJRQ1Maternal chrononutrition during pregnancy and the composition of intestinal and placental microbiota
Kurtbeyoglu, Emine; Caferoglu Akin, Zeynep; Ozdemir, Fatma
Background: Disrupted feeding timing may alter microbiota profiles and contribute to metabolic disturbances. This study aimed to investigate the impact of maternal chrononutrition during pregnancy on maternal gut and placental microbiota. Methods: This study was conducted between April 2022 and February 2023 at Erciyes University Faculty of Medicine Hospitals and Kayseri Private Dünyam Hospital in Kayseri, Türkiye, among healthy pregnant women with predominantly daytime feeding (pDT, n = 10) or predominantly nighttime feeding (pNT, n = 10). A questionnaire was administered, and three-day food consumption diaries were recorded at both 20–26 and 32–36 weeks of gestation. Fecal samples were collected at 32–36 weeks of gestation, and placental samples were collected at birth and stored at -80 °C until analysis. Results: Although total daily energy intake at both gestational periods (20–26 and 32–36 weeks) was similar between the groups, gestational weight gain was greater in the pNT group [16.30 (5.25) kg] than in the pDT group [11.90 (3.41) kg] (p = 0.039). Compared with the pDT group, the Firmicutes: Bacteroidetes ratio was higher in the maternal gut microbiota of the pNT group. Furthermore, Bacilli, Lactobacillales, Lactobacillaceae, and Lactobacillus were significantly more abundant in the pDT group than in the pNT group (p < 0.05). The intestinal and placental microbiota of the pDT and pNT groups had similar alpha and beta diversity. Conclusions: Our findings suggest that predominantly daytime or nighttime feeding during pregnancy may influence the composition of maternal gut and placental microbiota. These microbiome alterations may have potential implications for maternal and infant health; however, larger longitudinal studies are needed to clarify their long-term relevance, including possible links with fetal programming.
- MakaleAçık Erişim2026Scopus SJRQ1Physicochemical properties of fifteen flower honey samples from five districts in Türkiye
Ucuncu, Osman; Kul, Merve Kalafat; Baltaci, Cemalettin; Aykoc, Ayse Muslu
This study analyzed the physicochemical characteristics, mineral composition, and antioxidant potential of fifteen floral honey samples collected from five districts of Gümüşhane, Türkiye. The average values for moisture (17.44 g/100 g), insoluble solids (0.04 g/100 g), conductivity (0.35 mS/cm), diastase activity (54.15 DN), free acidity (38.18 meq/kg), and fructose + glucose content (68.95 g/100 g) were mostly within the acceptable limits defined by national honey standards. Proline content ranged from 562.66 to 1466.15 mg/kg, while hydroxymethylfurfural (0.37–18.89 mg/kg) confirmed the freshness of all samples. Potassium, calcium, sodium, and magnesium were identified as the major mineral elements in the analyzed honey samples, with considerable variation observed among samples collected from different districts. Antioxidant activity (Total phenolic content (mg GAE/100 g): 9.21–98.25; SC₅₀ (mg/mL): 5.23–41.29) revealed a strong antioxidant potential of Gümüşhane honeys. This work provides the first detailed characterization of Gümüşhane honeys, confirming their high physicochemical quality, rich mineral profile, and notable antioxidant potential, and underscores their value as a distinctive regional product with functional and commercial significance.
AtıfScopus4WoS5İncele - MakaleAçık Erişim2026Scopus SJRQ1Effects of inspiratory muscle training combined with circadian rhythm-based running programs in male children football players
Konca, Erkan; Yilmaz, Coşkun; Saç, Ajlan; Dal, Suzan; Halmatov, Medera; Akıllıoğlu, Osman; Bayrakdaroğlu, Serdar
Background: Inspiratory muscle training (IMT) has been suggested to improve respiratory function and physical performance; however, evidence in preadolescent athletes remains limited. This study examined whether adding IMT to circadian rhythm–based running programs would enhance functional and pulmonary outcomes in preadolescent male football players with at least two years of regular football training experience. Methods: Seventy-five boys aged 10–12 years were categorized into morning-, intermediate-, or evening-type groups based on Morningness–Eveningness Scale for Children (MESC) scores, and each chronotype group was assigned to its corresponding running protocol with or without IMT. Over six weeks, participants completed circadian rhythm–based running sessions, and IMT groups performed graded-load IMT. Pre- and post-intervention assessments included agility, six-minute walk test (6MWT), pulmonary function (FVC, FEV₁, FEV₁/FVC), and respiratory muscle strength (MIP, MEP). Results: Agility and 6MWT performance improved most in the morning running + IMT group compared with evening running + IMT and running-only groups (p < 0.001). FVC and FEV₁ increased in both IMT groups, though gains were modest and smaller in the running-only group. Improvements in MIP and MEP did not differ significantly between groups. Conclusion: Combining IMT with morning running produced the greatest improvements in agility and functional performance, while pulmonary gains were moderate and respiratory muscle strength changes were comparable across groups. IMT may provide additional benefit when integrated into chronotype-aligned morning training in preadolescent football players. Trial registration: Effects of Inspiratory Muscle Training Combined with Circadian Rhythm-based Running Programs in Children Football Players, ClinicalTrials.gov: NCT06817486, Date: 27-01-2025.
AtıfScopus1WoS1OpenAlex1İncele - Derleme MakaleAçık Erişim2026Scopus SJRQ2Physiological responses and adaptive mechanisms of amphibians and reptiles to multiple interacting environmental stressors: an integrative review
Kurnaz, Muammer
This integrative review synthesizes current knowledge on the physiological responses and adaptive mechanisms of amphibians and reptiles to multiple interacting environmental stressors, with particular emphasis on synergistic effects among temperature, hydric stress, disease, and pollution. Given the stronger empirical basis for amphibians in the existing literature, amphibian responses are covered in greater depth, while reptile-specific physiology, immunology, and emerging infectious diseases are explicitly addressed in dedicated sections throughout the review. Critical thermal tolerance analyses reveal that approximately 7.5% of amphibian species will exceed their physiological limits under a 4 °C warming scenario, with tropical lowland species already operating near their CTmax thresholds. Thermal plasticity is limited, with acclimation responses averaging only 0.13 °C increase in CTmax per 1 °C environmental warming—insufficient to track rapid climate change. Water balance regulation shows dramatic interspecific variation, with cutaneous resistance ranging from 0.05 s/cm in aquatic amphibians to >1000 s/cm in desert-adapted reptiles. Synergistic interactions between thermal and hydric stress significantly amplify vulnerability, particularly in dehydration scenarios that reduce critical thermal limits. Chemical pollutants, including heavy metals and pesticides, cause developmental abnormalities (535% increase in malformation frequency), immunosuppression, and endocrine disruption across multiple life stages. Emerging infectious diseases, particularly chytridiomycosis (Batrachochytrium dendrobatidis and B. salamandrivorans) and ranaviruses, drive mass mortality events globally, with co-infections exacerbating population declines. Climate change intensifies disease susceptibility through stress-mediated immunosuppression and altered pathogen dynamics. Adaptive capacity varies markedly among species. While amphibians exhibit strong phenological responses (2-4× greater than other taxa), genetic adaptation potential remains limited by narrow dispersal abilities and habitat fragmentation. Microhabitat buffering can reduce thermal extremes by several degrees but depends critically on habitat structural integrity. This review demonstrates that the pace of anthropogenic change challenges the adaptive capacity of most species, necessitating integrated conservation strategies including microhabitat preservation, climate corridor establishment, pollution mitigation, disease surveillance, and ex-situ conservation programs.
AtıfWoS2OpenAlex6İncele - MakaleAçık Erişim2026Scopus SJRQ2Waste to resource approach: CoFe2O4-modified spent tea waste for magnetic solid-phase extraction of toxic metal ions from water samples
Seker, Serdal; Ozdes, Duygu; Duran, Celal
In this research, within the framework of a waste-to-resource conversion approach, biochar obtained from spent tea waste (STWB), a widely available and cost-free biomass source, was modified with magnetic CoFe2O4 nanoparticles to develop an environmentally friendly adsorbent (CoFe2O4/STWB). The applicability of this material for efficient separation and preconcentration of Cd(ii), Pb(ii), and Ni(ii) ions from mining wastewater, stream water, and wastewater samples collected from an organized industrial zone was systematically investigated using the solid phase extraction (SPE) method. Optimization of the experimental variables was conducted to enhance the extraction performance of the target analyte ions. The fact that the adsorption and desorption equilibrium times occur in less than 1 min demonstrates the rapid and highly efficient extraction performance of the developed adsorbent. Langmuir isotherm model analysis revealed that CoFe2O4/STWB exhibits adsorption capacities of 69.4 mg g−1 for Cd(ii), 185.2 mg g−1 for Pb(ii), and 45.2 mg g−1 for Ni(ii). In contrast, the corresponding adsorption capacities obtained for unmodified STWB were considerably lower, with values of 42.9, 75.8, and 16.8 mg g−1 for Cd(ii), Pb(ii), and Ni(ii), respectively. These results clearly demonstrate that modification with CoFe2O4 significantly enhances the adsorption performance of STWB. Consequently, CoFe2O4-modified spent tea waste can be regarded as an effective, economical, and sustainable adsorbent for trace heavy metal analysis in environmental water samples, owing to its rapid extraction kinetics, high adsorption capacity, and low detection limits. This journal is
AtıfScopus1WoS1İncele - MakaleAçık Erişim2026Scopus SJRQ1Potentially Toxic Metal Levels in Cheeses Produced in Türkiye: Regional Variation, Milk Source, Ripening Stage, Production Type, and Associated Dietary Exposure and Health Risk
Gürmeriç, Hüseyin Ender; Şengül, Mustafa; Basaran, Burhan
This study investigated potentially toxic metal (PTM) levels in cheeses produced in different regions of Türkiye and evaluated the associated dietary exposure and non-carcinogenic health risk. A total of 84 cheese samples were collected from seven geographical regions and classified according to milk source, ripening stage, and production type. After microwave-assisted acid digestion, PTM levels were quantified by inductively coupled plasma mass spectrometry (ICP-MS), and exposure and non-carcinogenic risk were evaluated using Estimated Daily Intake (EDI), Target Hazard Quotient (THQ), and Hazard Index (HI). Aluminium (Al), iron (Fe), and zinc (Zn) ranged from <0.00215 to 7.29,<0.00769 to 38.8, and 0.68 to 56.6 mg/kg wet weight, respectively, whereas chromium (Cr), nickel (Ni), copper (Cu), selenium (Se), cadmium (Cd), and lead (Pb) ranged from <0.58 to 244, <1.26 to 369, <1.88 to 4067, <0.91 to 1378, <0.06 to 12.3, and <2.19 to 1754 µg/kg wet weight, respectively. Values marked with “<” represent concentrations below the limit of quantification (LOQ). Arsenic (As) was not detected in any sample. Significant differences were observed for selected PTMs according to ripening stage, milk source, production type, and region (p<0.05). The toxicological contribution (TC) values for nutritional PTM exposure were low. THQ and HI values remained below 1, suggesting a low overall non-carcinogenic risk; however, Pb exceedances in some samples indicate the need for continued PTM monitoring.
- MakaleYalnız künye2026Scopus SJRQ2Food reward sensitivity mediates the association between chemosensory pleasure and adiposity in young adults
Kurtbeyoglu, Emine; Caferoglu Akin, Zeynep; Aslan Gonul, Busra
This cross-sectional study investigated whether food reward sensitivity mediates the association between chemosensory pleasure and adiposity in young adults. A total of 300 university students completed the Chemosensory Pleasure Scale (CPS), the Power of Food Scale (PFS), and the Beck Depression Inventory (BDI), alongside anthropometric assessments. Chemosensory pleasure was strongly and positively associated with food reward sensitivity (β = 0.620, p < .001), and this relationship remained robust after adjustment for age, sex, BMI, and depressive symptoms. While chemosensory pleasure showed only weak direct associations with adiposity indicators, food reward sensitivity was positively associated with body fat percentage. Mediation analyses demonstrated a significant indirect effect of chemosensory pleasure on body fat percentage through food reward sensitivity (indirect effect = 0.105; 95% CI: 0.039–0.179), indicating an indirect-only pathway. Although sex-stratified analyses suggested some pattern differences, moderated mediation analyses did not support a significant moderating role of sex. These findings suggest that chemosensory pleasure may be related to adiposity primarily when accompanied by increased food reward sensitivity. The results highlight food reward sensitivity as a potential psychological mechanism linking sensory responsiveness to adiposity.
- MakaleAçık Erişim2026Scopus SJRQ1Antibacterial Efficiency and Osteoblast Viability of Ag/AgO/Ag2O Nanoparticles on Microarc-Oxidized TiO2
Aktas, Sitki; Durdu, Salih; Bird, Toby W.; Ozcan, Kadriye; Yigitturk, Gurkan; Aktug, Salim Levent; Usta, Metin; Acet, Tuba; Pratt, Andrew
Infections associated with titanium-based medical and dental implants present a major clinical challenge, as they can compromise osseointegration and long-term implant stability. Silver-based nanoparticles (NPs) are widely recognized for their strong antimicrobial properties, and when combined with titanium, they hold significant promise for developing infection-resistant and biocompatible implant surfaces. In this study, Ag/AgO/Ag2O NPs were deposited onto highly porous TiO2 layers formed on the Ti6Al4V alloy by microarc oxidation (MAO), with the aim of simultaneously enhancing antibacterial performance and supporting osteoblast activity. The NPs exhibited a predominant size of 8.7 ± 0.1 nm, with smaller particles oxidized to AgO and Ag2O, and larger particles (∼10 nm) composed of metallic Ag. SEM evaluation revealed that the NPs were homogeneously dispersed across the oxide surfaces without altering the rough and porous morphology of TiO2. The MAO-treated surfaces initially showed hydrophobic behavior (contact angle of 94.1 ± 0.3°), which shifted to hydrophilic after Ag/AgO/Ag2O NP deposition due to increased hydroxyl group formation. Antibacterial assays against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) revealed a significant enhancement in antibacterial activity, particularly for surfaces with the highest Ag/AgO/Ag2O NP density. Meanwhile, osteoblast cell viability assays demonstrated no reduction in metabolic activity after 72 h, and SEM images confirmed cell adhesion and proliferation. Overall, these findings highlight the potential of Ag/AgO/Ag2O NP-modified TiO2 surfaces as multifunctional coatings that combine infection resistance with osteoblast compatibility, offering promising applications in dental and orthopedic implants.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ1Financial literacy and psychological vulnerability to financial exploitation: the roles of financial anxiety, self-confidence, and behavior
Çam, Alper Veli; Soydaş, Şafak Sönmez; Özbek, Adem; Çam, Handan
Background: Financial exploitation constitutes a significant psychological vulnerability shaped by cognitive resources, emotional regulation, and financial decision-making behaviors. While financial literacy is widely recognized as a protective factor, limited empirical evidence disentangles the distinct psychological roles of financial knowledge, attitudes, and behaviors in reducing vulnerability to financial exploitation. Methods: This cross-sectional study analyzed survey data from 565 adults in Türkiye. Financial literacy was conceptualized as a multidimensional construct comprising financial knowledge, financial attitude, and financial behavior. Vulnerability to financial exploitation was assessed through three psychosocial indicators: self-confidence, financial anxiety, and financial satisfaction. Structural Equation Modeling (SEM) was employed to examine the relationships among cognitive, behavioral, and emotional components. Results: Financial knowledge was significantly associated with lower financial anxiety and higher financial satisfaction but showed no direct effect on self-confidence. Financial behavior emerged as the most robust protective factor, significantly enhancing self-confidence and financial satisfaction while substantially reducing financial anxiety. Financial attitude was positively related to financial satisfaction but did not significantly influence anxiety or self-confidence. Financial anxiety demonstrated a strong negative association with both self-confidence and financial satisfaction. Conclusions: Financial exploitation vulnerability is driven by interconnected psychological mechanisms rather than cognitive factors alone. The findings highlight the central role of behavior-based financial competencies and emotional regulation in strengthening financial resilience. Interventions aimed at preventing financial exploitation should prioritize behavioral skill development and psychological risk screening alongside traditional financial education approaches.
- MakaleAçık Erişim2026Scopus SJRQ1Nurses’ Workplace Discrimination Experiences and Their Reflections on Career Development: A Qualitative Study
Koroglu Kaba, Nagihan; Apaydin, Emine; Kulakaç, Nurşen
Aim: This study was conducted to examine how nurses experience discriminatory behaviors in the workplace and how these experiences are reflected in their career development. Background: Although discrimination constitutes a significant challenge in nurses’ professional lives, qualitative research examining how these experiences influence their career development processes remains limited. Methods: This phenomenological study was conducted with nurses working in a public hospital in Turkey. Semi-structured individual interviews were conducted with 21 nurses during the study. Participants were selected from various clinical settings through purposive sampling. Data were analyzed using Colaizzi's seven-step content analysis method. Ethics committee approval was obtained for this study. The Consolidated Criteria for Reporting Qualitative Research checklist guided the study reporting. Results: Five main themes with seven subthemes emerged: (1) Discrimination Experiences (types of discrimination, sources of discrimination, emotions/feelings), (2) Reporting Behavior (decision and consequences of reporting, reasons for not reporting), (3) Impact of Discrimination on Career Development (supportive effect, hindering effect), (4) Coping Strategies, and (5) Suggestions for Preventing Discrimination. Discussion: These themes highlight that discrimination is a multidimensional phenomenon and that holistic approaches must be developed at emotional, structural, professional, and institutional levels to cope with it. Conclusion: For some nurses, discrimination acts as a transformative process that supports career development, while for others, it represents a significant barrier to professional advancement. Implications for Nursing/Nursing Policy: The findings highlight the need to strengthen reporting mechanisms, establish a supportive work culture, and implement inclusive institutional policies that promote career development.
AtıfScopus1OpenAlex1İncele - MakaleYalnız künye2026Scopus SJRQ1Valorization of tea industry waste into boric acid–activated carbon for phenol removal from aqueous solutions
Duran, Celal; Ozdes, Duygu; Ozdemir, Olcay; Onal, Yunus; Gundogdu, Ali
The tea industry generates substantial quantities of solid waste with limited high-value industrial applications. In this study, tea industry waste was converted into boric acid-activated carbon (BA–TAC) through a simple one-step chemical activation process and evaluated as an adsorbent for phenol removal from aqueous solutions. BA–TAC exhibited a mixed micro–mesoporous structure with a BET surface area of 592.59 m2 g−1. The adsorption performance was investigated as a function of solution pH, contact time, and initial phenol concentration. Adsorption kinetics were evaluated using pseudo-first order, pseudo-second order, Elovich, Avrami, and intraparticle diffusion models, whereas equilibrium data were analyzed using Langmuir, Freundlich, and Sips isotherms. Linear, pseudo-linear, and non-linear regression approaches were comparatively evaluated, demonstrating the limitations of conventional linearization and the superiority of direct non-linear regression. Moreover, the so-called linearized forms of multi-parameter models such as Sips are not truly linear because iterative parameter estimation remains necessary. The maximum experimental phenol adsorption capacity reached 101.80 mg g−1 despite the moderate BET surface area of BA–TAC. The experimentally determined natural pH and pHpzc values, together with the limited desorption efficiency, indicated that adsorption was governed predominantly by surface chemical interactions rather than electrostatic attraction alone. XPS analysis confirmed the incorporation of boron-containing surface functionalities, highlighting their contribution to phenol adsorption. Overall, this study demonstrates the successful valorization of tea industry waste into a functional boron-modified activated carbon while providing methodological guidance for reliable adsorption kinetics and equilibrium modeling, thereby supporting sustainable waste valorization.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2026Scopus SJRQ1Development and psychometric evaluation of the healthy internet use scale for adolescents
Özparlak, Arif; Gül, Uğur; Karakaya, Dudu; Efe, Emine
Objective The aim of this study was to develop the Healthy Internet Use Scale for Adolescents (HIUS-A) and examine its psychometric properties in order to evaluate healthy internet use (HIU) among adolescents. Methods The study was conducted according to a methodological, correlational and cross-sectional design. Data was collected between September and December 2025 at three middle schools and three high schools in the province of Antalya, Türkiye. The study used a stratified sampling method, and it was completed with 516 adolescents. The scale's content validity was examined through expert evaluation, and its construct validity was tested through exploratory and confirmatory factor analyses. The reliability of the scale was assessed using Cronbach's alpha coefficient, split-half reliability, and item-total correlations. Results The analyses revealed that HIUS-A exhibited a two-factor structure explaining 49.1% of the total variance. These factors were named “self-control” and “conscious use”. Confirmatory factor analysis findings revealed that the model showed a good level of fit (χ2/sd = 1.450; RMSEA = 0.042; SRMR = 0.039; CFI = 0.981). The internal consistency coefficient was calculated as 0.864 for the total scale, 0.855 for the “self-control” subscale, and 0.711 for the “conscious use” subscale. Conclusion HIUS-A is a valid and reliable ten-item assessment tool for evaluating healthy internet use in adolescents. Implications for practice The scale may be used by nurses and other healthcare professionals to determine HIU levels in adolescents and to evaluate the effectiveness of intervention studies relating to HIU.
- MakaleAçık Erişim2026Scopus SJRQ4Assessing the Predictive Value of Kolmogorov–Arnold Networks for the No–Reflow Phenomenon in ST–Segment Elevation Myocardial Infarction: A Comparative Machine Learning Study; [ST Segment Yükselmeli Miyokard Enfarktüsünde No–Reflow Fenomeni için Kolmogorov–Arnold Ağlarının Öngörü Değerinin Değerlendirilmesi: Karşılaştırmalı Makine Öğrenimi Çalışması]
Taşolar, Hakan; Bayramoğlu, Adil; Günen, Mehmet Akif; Levent, Sümeyye; Güral, Yunus; Halisdemir, Nurhan
Objective: The no-reflow phenomenon in ST-segment elevation myocardial infarction (STEMI) is a significant clinical issue associated with poor cardiovascular outcomes. This study aimed to develop and compare multiple supervised machine learning algorithms, including the recently introduced Kolmogorov-Arnold Network (KAN), to predict the occurrence of the no-reflow phenomenon in patients with STEMI undergoing primary percutaneous coronary intervention (PCI). Method: This prospective, single-center study included 890 consecutive STEMI patients undergoing primary PCI. The Synthetic Minority Over-sampling Technique (SMOTE) was utilized to address class imbalance during training. Feature selection using analysis of variance (ANOVA) F-statistics and validation of feature independence (Variance Inflation Factor [VIF] < 5) identified ejection fraction (EF), baseline troponin level, stent length, B-type natriuretic peptide (BNP) level, and total ischemic time as the most influential predictors. Results: The KAN and Extreme Gradient Boosting (XGBoost) models achieved the highest predictive accuracy (area under the curve > 0.98, F1 > 0.95), outperforming traditional models such as logistic regression and decision tree classifiers (DeLong test, P < 0.001). Feature selection improved efficiency and reduced runtime by 20–40%, while Shapley Additive exPlanations-based (SHAP-based) explainability confirmed that the predictions were physiologically consistent: higher EF and lower BNP reduced the probability of no-reflow, whereas longer stent length and ischemic time increased it. The superior performance of KAN and XGBoost underscores the importance of modeling nonlinear relationships and multidimensional interactions among clinical, laboratory, and procedural variables. Conclusion: These findings suggest that KAN may serve as a reliable analytical framework for exploring complex cardiovascular outcomes. However, further multicenter and externally validated studies are needed to confirm its generalizability and potential role in clinical risk assessment.
AtıfScopus5WoS5OpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ3The Impact of Live and Robotic Cat-Assisted Therapy on Symptoms and Happiness Levels in Patients With Cancer Following Chemotherapy
Can, Aysun Akçakaya; Demirağ, Hatice; Hintistan, Sevilay
OBJECTIVES: To examine the effects of live and robotic cat-assisted therapies on chemotherapyinduced symptoms and happiness levels in patients with cancer. SAMPLE & SETTING: 45 patients were randomly assigned to live cat therapy, robotic cat therapy, or control groups in a university hospital. METHODS & VARIABLES: Data were collected between June 1 and September 1, 2023. Patients in therapy groups interacted with a live or robotic cat for 20 minutes twice weekly for three months. RESULTS: Although the live cat therapy group had higher median happiness scores than the robotic cat therapy group, differences in happiness and symptom scores between groups were not statistically significant. Both therapies alleviated chemotherapy-induced symptoms and enhanced emotional well-being, with robotic cat therapy showing slightly greater overall effectiveness. IMPLICATIONS FOR NURSING: Robotic pet therapy offers a feasible alternative where live animalassisted therapy is impractical. Integrating these therapies into oncology nursing can enhance symptom management and psychological support, promoting holistic, patient-centered care.
AtıfScopus1WoS1İncele - MakaleAçık Erişim2026Scopus SJRQ2Anesthesi̇a students’ behavi̇ors towards a medi̇cal errors: a phenomenologi̇cal quali̇tati̇ve scenari̇o study
Karadeni̇z, Havva; Erkuran, Hatun
Objective: This study is a qualitative scenario study designed to investigate the behaviors of associate degree anesthesia program students, who will work in operating rooms after graduation, in response to medical errors they may encounter in the future and how they cope with these errors. Materials and methods: This qualitative study was conducted using interpretive phenomenology. Research data were collected from 33 students enrolled in the Anesthesia Program, selected using purposive sampling, between October 2022 and January 2023. A hypothetical case scenario was prepared for the study, which anesthesiology technicians working in the operating room environment might encounter, and data were collected using a semi-structured interview technique. The data obtained were transcribed into written form on a computer and coded according to qualitative research methods. Results: In the inductive coding process, “felt emotions” were divided into two main categories: Challenging Emotions and Functional Emotions, while “behaviors” were divided into Desired Behaviors and Undesired Behaviors. Conclusion: The research found that students viewed medical errors as “a normal situation,” providing an opportunity to shed light on what students think about medical errors and to develop new educational strategies.
- MakaleAçık Erişim2026Scopus SJRQ1Structure-Dependent Triglyceride Protection of Freeze-Dried Lactiplantibacillus plantarum: Storage Protection Window, Lipid Oxidation, and Stress Adaptation
Sun, Zheneng; Zhang, Nan; Wang, Xiaomai; Wei, Xinyao; Ozturk, Samet; Liu, Shuxiang
Lipid-rich matrices can protect probiotics by limiting direct exposure to moisture, oxygen, and gastrointestinal stressors. However, triglycerides are chemically dynamic during storage, and differences in fatty acid structure and oxidation susceptibility may determine whether they exert protective or detrimental effects. In this study, tricaprylin, triolein, and trilinolein were evaluated as post-drying lipid storage matrices for freeze-dried Lactiplantibacillus plantarum 124 during storage at 25 °C, and 37 °C was used to accelerate lipid oxidation. Survival during storage, fatty acid chain retention, oxidation-derived products, stress tolerance, qualitative confocal imaging of membrane-integrity patterns, and transcriptomic responses were analyzed. After 30 d at 25 °C, log reductions were 0.30, 0.24, and 0.24 log10 units in the tricaprylin, triolein, and trilinolein groups, respectively, compared with 0.60 log10 units in the oil-free control, defining a common protective window. Tricaprylin showed the highest fatty acid chain retention, whereas trilinolein exhibited the greatest loss and strongest oxidative change. GC–MS detected no representative oxidation-derived products in tricaprylin, while unsaturated triglycerides generated dimethyl azelate and methyl 9-oxononanoate. Cells recovered from the protective window showed improved acid and bile tolerance, with survival increasing from 30.48% to 53.43–55.65% and from 14.85% to 22.49–27.79%, respectively. Confocal imaging further showed better-preserved membrane-integrity patterns in the triglyceride-treated groups after acid exposure. Transcriptomics indicated enhanced transport, redox, DNA-related, and cell-envelope responses, accompanied by reduced translation and growth-associated metabolism. Within the experimental conditions tested, these results suggest that triglyceride-associated attenuation of viability loss varies among triglyceride systems and across storage stages, while excessive oxidation of unsaturated triglycerides may weaken probiotic stability.