Yazarlar
- Uzun, Sevda(79)
- Kulakaç, Nurşen(40)
- Turan, Ibrahim(33)
- Demir, Selim(32)
- Türkkan, Tuğba(24)
- Aydin, Aydanur(23)
- Topal, Fevzi(22)
- Aliyazicioglu, Yuksel(21)
- Tuncer, Metin(21)
- Bayrakdaroglu, Serdar(19)
- Demirağ, Hatice(19)
- Hintistan, Sevilay(18)
- Topal, Meryem(18)
- Yılmaz, Coşkun(18)
- Bayrakdaroğlu, Serdar(15)
- Yilmaz, Coskun(15)
- Mentese, Ahmet(14)
- Reis, Hatice Catal(14)
- Demir Doğan, Melike(13)
- Emirza, Elif Güzide(13)
- Memetoglu, Mehmet Erdem(13)
- Tuncer, Gülsüm Zekiye(13)
- Bülbül, Kenan(12)
- Cin, Aynur(12)
- Düzgün, Azer Özad(12)
- Koçak, Tevfik(12)
- Odaci, Hatice(12)
- Oğuzhan, Hatice(12)
- Tonkaz, Duygu Erkal(12)
- Tonkaz, Mehmet(12)
- Turk, Veysel(12)
- Ceylan, Halil Ibrahim(11)
- Kilinc, Kagan(11)
- Köse, Aslı(11)
- Merdan, Mehmet(11)
- Acet, Tuba(10)
- Aksoy, Bahar(10)
- Aydin Sayilan, Aylin(10)
- Baltaci, Cemalettin(10)
- Deger, Orhan(10)
Yayınlar
- MakaleAçık Erişim2024Scopus SJRQ2Effect of micro-arc oxidation coatings with graphene oxide and graphite on osseointegration of titanium implants-an in vivo study
Tekin, Bahar; Dundar, Serkan; Tekin, Samet; Emine Sukuroglu, Ebru; Khurshid, Zohaib; Ezgi, Yusuf; Demirci, Fatih; Faheemuddin, Muhammad
Background: This in vivo study evaluated the effect of graphene oxide and graphite coatings, coupled with the micro-arc oxidation (MAO) surface roughening technique, known for their mechanical strength, chemical stability, and antibacterial properties. The main objective was to assess the degree of improvement in osseointegration of titanium implants resulting from these interventions. Materials and methods: In this study, 32 female rats were utilized and randomly allocated into four groups (n = 8 each): machined surface titanium implants (control), those roughened by the MAO method, those coated with graphene oxide-doped MAO, and those with a graphite-doped MAO coating. Titanium implants were surgically placed in the right tibia of the rats. Rats undergoing no additional procedures during the 4-week experimental period were sacrificed at the end. Then, the implants and surrounding bone tissues were separated and embedded in acrylic blocks for reverse torque analysis. Using a digital torque device, the rotational force was applied to all samples using a hex driver and racquet until implant separation from the bone occurred, with the corresponding values recorded on the digital display. Then, statistical analysis was performed to analyze the data. Results: No statistically significant difference between the groups was observed in the biomechanical bone–implant connection levels (N/cm) (P = 0.268). Post-hoc tests were not required because no discernible differences were identified between the groups. Conclusion: Within the scope of this study, implants treated with the MAO method, along with those coated with graphene oxide- and graphite-doped MAO method, did not exhibit significant superiority in terms of osseointegration compared to machined surface titanium implants.
AtıfScopus9WoS8OpenAlex10
İncele - MakaleAçık Erişim2024Scopus SJRQ4Examination of Mental Stamina and Athlete Injury Anxiety Levels of Wrestlers
Ünlü, Çisem; Çevi̇Ker, Abdulkerim; Turgut, Abdüsselam; Kusan, Osman; Tezcan, Efecan; Gür, Kübra; Yildirim, Turgut
The aim of this research is to examine the mental endurance and athlete injury anxiety levels of athletes interested in wrestling from some demographic perspectives. In the study, a descriptive scanning model was used. The universe of the research consists of athletes from various cities of Turkey who are interested in wrestling, and the sample consists of 341 athletes selected by random sampling method among wrestling athletes from Ankara, Gümüşhane, Istanbul, Samsun and İzmir, Kayseri. As a data collection tool, the demographic information form developed by the researchers was used "Athlete Injury Anxiety Scale". In the study, the assumption of normality was first examined with the Kolmogorov-Smirnov and Shapiro-Wilk tests in the statistical evaluation of the data. The research findings were given as n (%), mean and standard deviation values, and the findings were considered significant at the p<0.05 level. In the study, there was no significant relationship between age, undergraduate status and educational status variables, athlete injury anxiety levels and mental toughness levels; When the athlete's age, athlete's injury status, gender, number of nationality variables were examined, it was determined that there was a significant difference in some sub-dimensions of the mental toughness inventory and in the total scores of the scale. As a result, it can be said that demographic variables such as age, gender, being a national athlete are effective on the mental endurance and disability anxiety of the athletes.
AtıfScopus4OpenAlex2İncele - MakaleYalnız künye2024Scopus SJRQ2Sulfonamide derivatives with benzothiazole scaffold: Synthesis and carbonic anhydrase I–II inhibition properties
Öztürk, Cansu; Kalay, Erbay; Gerni, Serpil; Balci, Neslihan; Tokali, Feyzi Sinan; Aslan, Osman Nuri; Polat, Emrah
The secondary sulfonamide derivatives containing benzothiazole scaffold (1–10) were synthesized to determine their inhibition properties on two physiologically essential human carbonic anhydrases isoforms (hCAs, EC, 4.2.1.1), hCA I, and hCA II. The inhibitory effects of the compounds on hCA I and hCA II isoenzymes were investigated by comparing their IC50 and Ki values. The Ki values of compounds (1–10) against hCA I and hCA II are in the range of 0.052 ± 0.022–0.971 ± 0.280 and 0.025 ± 0.010–0.682 ± 0.335, respectively. Some of these inhibited the enzyme more effectively than the standard drug, acetazolamide. In particular, compounds 5 and 4 were found to be most effective on hCA I and hCA II.
AtıfScopus13WoS11OpenAlex13İncele - MakaleYalnız künye2024Scopus SJRQ2Is environment destiny? Spatial analysis of the relationship between geographic factors and obesity in Türkiye
Yılmaz, Hacı Ömer; Günen, Mehmet Akif
This study aims to evaluate the relationship of geographical factors, including precipitation, slope, air pollution and elevation with adult obesity prevalence in Türkiye (TR) using a cross-regional study design. Ordinary least squares (OLS) and geographically weighted regression (GWR) were performed to evaluate the spatial variation in the relationship between all geographic factors and obesity prevalence. In the model, a positive relationship was found between obesity prevalence and slope, whereas a negative significant relationship was determined between obesity prevalence and elevation (p < 0.05). These results, revealing spatially varying associations, were very useful in refining the interpretations of the statistical results on adult obesity. This research suggests that geographical factors should be considered as one of the components of the obesogenic environment. In addition, it is recommended that national and international strategies to overcome obesity should be restructured by taking into account the geographical characteristics of the region.
AtıfScopus4WoS4OpenAlex5İncele - MakaleAçık Erişim2024Scopus SJRQ2Impact of Preoperative Progressive Relaxation Exercises on Postoperative Pain, Comfort, and Recovery : A Randomized Controlled Trial
Kulakaç, Nurşen; Sayılan, Aylin Aydın
This randomized controlled trial aimed to investigate the impact of preoperative progressive relaxation exercises on postoperative pain, comfort, and quality of recovery. The study was conducted between June and November 2023, involving 68 patients undergoing surgical intervention and hospitalized in the surgical clinic. Data were collected using the Personal Information Form, the Visual Analog Scale (VAS)-Pain, the Perianesthesia Comfort Scale, and the Quality of Recovery Questionnaire. At the sixth postoperative hour, no significant difference was observed in pain levels between the experimental and control groups (P > .05). However, the VAS scores for the experimental group at the 12th and 24th postoperative hours were significantly lower than those of the control group (P < .001). Furthermore, 24 hours postoperatively, the experimental group demonstrated significantly higher quality of recovery (P < .001) and comfort levels (P < .001) than the control group. This study concludes that patients engaged in relaxation exercises exhibited lower VAS scores and higher levels of recovery and comfort.
AtıfScopus2WoS1OpenAlex3İncele - MakaleAçık Erişim2024Scopus SJRQ4Changes in acute and late toxicity and patient-reported health-related quality of life following radiotherapy in women with breast cancer: A 1-year longitudinal study
Uslu, Gonca Hanedan; Aydin, Aydanur; Gürsoy, Ayla
Objective: The objective of this study was to investigate the frequency of acute and late toxicities, as well as changes in the quality of life (QOL) for breast cancer patients following radiotherapy (RT). Materials and Methods: A total of 108 breast cancer women were recruited for this prospective study. Data were collected at various intervals; prior to, and 1, 3, 6 months, and 1 year after radiation therapy. The primary outcomes were toxicity radiation therapy oncology group/European Organization for Research and Treatment of Cancer (EORTC) criteria. Our secondary outcome was QOL, measured using EORTC QLQ-C30 and Edmonton Symptom Assessment Scale. We employed Friedman's two-way analysis to evaluate the changes in QOL over the course of 1 year. Results: The early toxicities that are most commonly experienced include pharyngeal, skin, and mucous membrane toxicity. Late toxicities frequently involve skin and submucosal toxicity. To measure patient functionality, all functional subscale scores except for the patient's emotional state increased over time compared to pre-RT. Symptoms of the patients, which were included in the QOL symptom scale, decreased during the follow-up period, except for fatigue; however, changes in pain, insomnia, and loss of appetite did not significantly change. We identified the analogous symptom profiles in Edmonton. Although patients' overall health scores declined in the 1 st and 3 rd months after radiotherapy (RT), they rebounded at 6 and 12 months. Conclusion: For breast cancer patients, RT did not adversely affect functional capacity or exacerbate symptoms, but persistent fatigue did increase during the observation period. Health-care professionals ought to devise strategies to assist patients with skin toxicity and fatigue.
AtıfScopus2OpenAlex2İncele - MakaleAçık Erişim2024Scopus SJRQ1A study on effective data preprocessing and augmentation method in diabetic retinopathy classification using pre-trained deep learning approaches
İncir, Ramazan; Bozkurt, Ferhat
High glucose levels in the blood not only damage different tissues and organs of the body, but also cause adverse effects on the eye. This condition is called diabetic retinopathy (DR). DR can cause blurred vision, darkening of the field of vision, and severe vision loss. The number of people infected with the disease is increasing in our country and worldwide. The time-consuming physician check-ups and the presence of small lesions indicate the need to develop diagnostic systems. Deep learning-based applications have become the trend for diagnosing and grading diseases from images. This study aims to create a meaningful and sufficient dataset using effective data preprocessing and affine transformation techniques in diabetic retinopathy classification. In this study, classification was performed using seven different pre-trained deep learning architectures. An experimental study of each technique was performed on the EyePACS dataset. An overfitting problem was encountered in the experimental results with the original data set. Thus, data preprocessing and data augmentation processes were carried out in order to eliminate overfitting by considering the imbalance between classes in the dataset. The classification performance obtained from each architecture was observed according to performance metrics of precision, recall, F1 Score, accuracy, and loss. In this study, the best performance was achieved with 97.65% test accuracy with the proposed EfficientNetV2-M network model.
AtıfScopus32WoS21OpenAlex34İncele - MakaleYalnız künye2024Scopus SJRQ2The Effect of Video-Based Simulation Training on Nursing Students' Motivation and Academic Achievement A Mixed Study
Koçan, Sema; Kulakaç, Nurşen; Aktug, Cemile; Demirel, Sevgül
This study was conducted to determine the effect of video-based simulation education on nursing students' motivation and academic achievement. The research was designed in a mixed model. A quasi-experimental method with a pretest-posttest control group was used for the quantitative part, and the descriptive phenomenology approach was used as the qualitative research method. The sample of the study consisted of second-year nursing students in two state universities in eastern Turkey. The data were collected with the Student Information Form, the Academic Achievement Test, and the Motivation Resources and Problems Scale using Google Forms Web application. Qualitative data were collected through online semistructured interview forms and focus group interviews. According to the results, the posttest academic achievement and Motivation Resources and Problems Scale mean scores of the students in the intervention group were significantly higher than those of the control group (P < .05). In the analysis of the qualitative, three main themes emerged: We felt fortunate that it increased information retention,” “We felt like we were in real practice environment,” and “It made us feel that we were nurses.” The results showed the use of video-based simulation can be suggested as a strategy to promote classroom teaching and engage students.
AtıfScopus5WoS3OpenAlex4İncele - MakaleAçık Erişim2024Scopus SJRQ1Enhancing brain tumor classification through ensemble attention mechanism
CELIK, Fatih; CELIK, Kemal; CELIK, Ayse
Brain tumors pose a serious threat to public health, impacting thousands of individuals directly or indirectly worldwide. Timely and accurate detection of these tumors is crucial for effective treatment and enhancing the quality of patients’ lives. The widely used brain imaging technique is magnetic resonance imaging, the precise identification of brain tumors in MRI images is challenging due to the diverse anatomical structures. This paper introduces an innovative approach known as the ensemble attention mechanism to address this challenge. Initially, the approach uses two networks to extract intermediate- and final-level feature maps from MobileNetV3 and EfficientNetB7. This assists in gathering the relevant feature maps from the different models at different levels. Then, the technique incorporates a co-attention mechanism into the intermediate and final feature map levels on both networks and ensembles them. This directs attention to certain regions to extract global-level features at different levels. Ensemble of attentive feature maps enabling the precise detection of various feature patterns within brain tumor images at both model, local, and global levels. This leads to an improvement in the classification process. The proposed system was evaluated on the Figshare dataset and achieved an accuracy of 98.94%, and 98.48% for the BraTS 2019 dataset which is superior to other methods. Thus, it is robust and suitable for brain tumor detection in healthcare systems.
AtıfScopus42WoS21OpenAlex42İncele - MakaleAçık Erişim2024Scopus SJRQ2Innovations in dairy technology: probiotics in Turkish white cheese production
Mazlum, Halit; Atasever, Mustafa
Cheese offers significant advantages as a probiotic carrier food compared to fermented milk and yoğurt due to its fat content, solid matrix, higher pH, low oxygen levels, and longer shelf life. This study examined Turkish white cheeses ripened with both classical starter culture (Lactococcus lactis subsp. lactis and Lactococcus lactis subsp. cremoris) and various probiotic cultures (Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus paracasei, and Bifidobacterium bifidum). The quality and functional properties of these cheeses were investigated to evaluate the effect of adding probiotics to traditional starter culture and their potential for use as carrier food for probiotics. During the 90-days ripening period, the numbers of L. acidophilus, L. casei, L. paracasei, and B. bifidum were determined to be in the range of 8.09 ± 0.34–8.65 ± 0.30, 7.19 ± 0.28–8.12 ± 0.90, 7.01 ± 1.45–8.73 ± 0.98, and 7.16 ± 1.10–8.21 ± 1.19 log cfu/g, respectively. The study found that probiotic levels in the cheese remained above the effective threshold (≥ 107 cfu/g) throughout the ripening process. This was accompanied by an increase in water-soluble nitrogen, an indicator of proteolysis, leading to higher ripening index values in all cheese samples. In terms of sensory evaluation, cheeses with L. acidophilus and L. paracasei were particularly well-received, scoring higher (7.90 ± 0.30–8.47 ± 0.12, 7.80 ± 0.34–8.75 ± 0.12, respectively) in taste and aroma than the others. Overall, probiotics positively influenced the quality and functional properties of the white cheese. Notably, the L. casei ATCC 393 strain, used for the first time in Turkish white cheese production, proved highly compatible with existing production technologies. It was concluded from the study that Turkish white cheese is a suitable food for transporting probiotics to the intestinal environment.
AtıfScopus5WoS5OpenAlex6İncele - MakaleAçık Erişim2024Scopus SJRQ4EVALUATION OF UNMET HEALTH NEEDS IN EUROPEAN UNION COUNTRIES: 2020-2021; [Évaluation des besoins de santé non satisfaits dans les pays de l’Union européenne: 2020-2021]
Köse, Aslı
The objective of the study. This study aimed to evaluate the effect of unmet health needs in European Union countries on Healthy Life Expectancy in 2020-2021 and determine the grouping of countries in this period. Material and methods. The study used unmet health needs data from the Eurostat database. Two models were created by path analysis using structural equation modeling. The impact of unmet health needs on life expectancy in 2020-2021 was evaluated. The cluster analysis grouped the European Union countries according to their unmet health needs. Results. The primary factor with the highest average contributing to unmet health needs in 2020-2021 was the absence of a requirement to report health issues. Among the reasons for postponing health needs in 2020-2021, the criterion of “absence of specialists” was determined to be the criterion with the lowest average. According to the cluster analysis, the most similar countries are the Netherlands and Austria, Albania and Serbia, while the least similar are Bulgaria and Belgium, Estonia and Belgium. Conclusions. During the pandemic, individuals gave up receiving health services due to their fear of catching COVID-19. It has been determined that unmet health needs did not affect life expectancy for 2020. In 2021, there was a statistically significant relationship between the “no need to report” unmet health need criterion and Healthy Life Year Expectancy. This study determined the “expensive, remote and transportation” criterion, which has the second highest average among the reasons for unmet health needs.
AtıfScopus2OpenAlex1İncele - MakaleYalnız künye2024Scopus SJRQ2The effect of a serious game-based web application on stoma care education for nursing students: A randomized controlled trial
Kulakaç, Nurşen; Çilingir, Dilek
Aim: This study was carried out in a randomized controlled manner to determine the effect of a serious game based web application on stoma care education for nursing students. Method: The learning styles and digital game motivation levels of the students in the study were determined, and aprior knowledge test was performed. While the website of the serious game-based application was open to the access of the intervention group for two weeks, no intervention was made for the control group. Second knowledge and skil lmeasurements were performed after two weeks for all students in the study, and evaluations of retention were performed four weekslater. Findings: The analyses revealed that the second and retention stoma care and colostomy irrigation knowledge test and skill scores of the intervention group were significantly higher than those of the control group (p<0.05). Conclusion: As the students' time to use the serious game increased, their knowledge tests and skill scores also increased significantly. Therefore, it was concluded that serious game technology had a positive effect on teaching nursing students the practice of stoma care.
AtıfScopus18WoS14OpenAlex21İncele - MakaleAçık Erişim2024Scopus SJRQ2Investigation of nurses’ general attitudes toward artificial intelligence and their perceptions of ChatGPT usage and influencing factors
Tuncer, Gülsüm Zekiye; Tuncer, Metin
Purpose: This study aimed to investigate professional nurses’ general attitudes toward artificial intelligence, their knowledge and perceptions of ChatGPT usage, and the influencing factors. Methods: The population of the research consists of nurses who follow a social media platform account in Turkey. The sample of the study consisted of 288 nurses who participated in the study between December 2023 and March 2024. Data were collected through an account on a social media platform via Google Forms using the Information Identification Questionnaire for ChatGPT and Artificial Intelligence Programs and the General Attitudes to Artificial Intelligence Scale (GAAIS). Results: The mean scores obtained from the overall GAAIS and its Positive Attitudes subscale from the participants in this study were 67.54 ± 13.14 and 41.89 ± 11.24, respectively. Of the participants, 48.3% knew about ChatGPT and artificial intelligence programs. Of the participants, 27.8% used ChatGPT and artificial intelligence programs. Their scores for the Positive Attitude subscale were higher than were the scores of those who did not use such programs. Of the participants, 84.4% thought that nurses should be made aware of ChatGPT and artificial intelligence programs, 67% thought that the use of these programs would contribute to nurses’ professional development, 42.4% thought that the use of these programs would not reduce nurses’ workload, and 58.3% thought that the use of these programs would positively affect patient care. Conclusion: In this study, it can be said that nurses in Turkey have positive attitudes toward integrating ChatGPT and AI programs to improve patient outcomes and add them to nursing practices. Implications for nursing practice: The present study in which nurses’ attitudes toward the implementation of ChatGPT and artificial intelligence programs were investigated is expected to provide information for healthcare institutions, policy makers and artificial intelligence developers on the integration of ChatGPT and artificial intelligence into nursing practice. It is necessary to create environments that use AI technologies that reduce the nursing workload of nurses in the clinical area and positively affect the quality of patient care.
AtıfScopus47WoS47OpenAlex46İncele - MakaleYalnız künye2024Scopus SJRQ1Perspectives on the mental health of immigrant children in the pediatric emergency department: a phenomenological study
Uzun, Sevda; Ustuner Top, Fadime
The concept of immigration is a complex phenomenon that goes far beyond mere relocation and refers to the transition from one social environment to another or from one culture to another. Immigration and its effects on children are regarded as global and interdisciplinary problems. This study aims to reveal the opinions of nurses working in the pediatric emergency department about the mental health of immigrant children. In this qualitative research, a phenomenological research design was used (N = 19).Interviews were conducted using a semi-structured interview form. Colaizzi’s method was used to analyze the data manually. Four categories, eleven themes, and thirty-eight sub-themes emerged from the analysis of the data. The difficulties nurses experience with immigrant children and their relatives in providing care include communication problems, cultural problems, and economic problems. The causes of mental health problems in immigrant children include war, exposure to immigration traumas, cultural assimilation problems, loss/absence of parents, economic reasons/excessive role overload, and exposure to neglect and/or abuse. Education, economic aid, communication, non-stigmatization, and social support were identified as significant sub-themes for practices to protect/promote children’s mental health. The study showed that immigrant children experience physical and mental problems. Nurses struggle to treat immigrant children effectively but have difficulties due to insufficient facilities. It may be suggested to include cultural care models in patient care.
- MakaleYalnız künye2024Scopus SJRQ1Human health risk assessment of heavy metals accumulation in different genders and tissues of whiting fish (Merlangius merlangus euxinus Nordmann, 1840) from Rize, Turkey
Şirin, Murat; Bayrak, Esra Yılmaz; Baltaş, Hasan
The contamination of fish resulting from marine pollution is a major concern, as it poses potential adverse effects on human health. Therefore, heavy metal concentrations (Cr, Fe, Ni, Cu, Zn, and Pb) in different genders and tissues (muscle, liver, gonads and gills) of whiting fish collected from fish markets in Rize province were determined by Inductively–coupled plasma optic emission spectrometry (ICP–OES). The concentration ranges of heavy metals in all tissue samples, based on the overall average, were as follows (mg/kg wet weight): Cr: 0.081–0.25, Fe: 2.3–40, Ni: 0.070–0.095, Cu: 0.33–1.01, Zn: 3.0–20, and Pb: 0.015–0.043. The results indicated that the liver and gills exhibited a higher metal accumulation capacity compared to other tissues, whereas the muscle consistently displayed the lowest metal concentrations. The metal concentrations in the muscle were found to be below the maximum permissible levels set by international organizations for seafood. Additionally, calculated estimated daily intake (EDI), metal pollution index (MPI), target hazard quotient (THQ), total exposure hazard index (HI), and target carcinogenic risk (TR) indicate no potential risk to humans from whiting fish consumption.
AtıfScopus22WoS21OpenAlex21İncele - Derleme MakaleAçık Erişim2024Scopus SJRQ2Effect of eHealth Interventions on Symptom Management in CABG Surgical Patients: A Systematic Review
Aydin, Aydanur; Celik, Sevilay Senol
This study aimed to evaluate the effectiveness of eHealth interventions on symptom management outcomes of patients undergoing CABG surgery. A systematic review was performed on CINAHL, PubMed, Web of Science, Ovid MEDLINE, and Scopus from 2006 to June 2022. The Joanna Briggs Institute's evaluation tools for RCT and quasi-experimental studies were used to assess the methodological quality of the publications included in this review and to determine the extent to which each publication addressed the possibility of bias in its design. The raters' agreement was determined by using Cohen's kappa test, which yielded a kappa coefficient of 0.51. (PROSPERO registration number: CRD42023398498). A systematic analysis of 11 publications involving 2.586 patients showed that the eHealth intervention effectively increased activity and self-management. eHealth interventions, which are also effective in the management of psychological problems, had results that were partially effective in pain management and effective in quality of life. Digital healthcare has become an important component of patient care. Nurses providing care should be aware that eHealth interventions are showing promising results in patient care.
AtıfScopus3WoS3OpenAlex3İncele - MakaleAçık Erişim2024Scopus SJRQ3Effects of different rest intervals in high intensity interval training programs on VO2max, body composition, and isokinetic strength and power
Kayhan, Recep Fatih; Bayrakdaroglu, Serdar; Ceylan, Halil Ibrahim; Eken, Ozgur; Bayrakdaroglu, Yesim; Badicu, Georgian; Al-Mhanna, Sameer Badri; Enoiu, Razvan-Sandu; Ardigo, Luca Paolo
The aim of this study was to evaluate the effect of 8 weeks of short and long rest running-based high-intensity training (HIIT) on body composition, isokinetic strength, and maximal oxygen uptake (VO2max). Nineteen physically active men were recruited to voluntarily participate in the study. The participants were grouped using the closed-envelope randomized method as HIIT with a short rest (HIITS, n = 9; age: 19.60 +/- 1.34 years) and HIIT with a long rest (HIITL, n = 10; age: 19.77 +/- 0.97). Pre and post the 8-week running-based HIIT program, body mass index and body fat % were measured and all subjects performed isokinetic strength tests to determine their hamstring (H)/quadriceps (Q) peak torque ratio and the peak power and peak work for their H and Q muscles. The participants also underwent a graded exercise test to determine their VO2max. Statistical analysis performed with One-Way Variance Analysis and Bonferroni correction post hoc tests. As a result of the study, there were no significant differences between the pre- and post-training isokinetic strength parameters for the H and Q of HIITL and HIITS at velocities of 60 and 240(degrees)s(-1). The VO2max did not change for HIITS training but the VO2max increased (p < 0.05) for HIITL training. In conclusion, that HIITL and HIITS programs for 8 weeks did not change the relative and absolute strength, force production and the VO2max, but the VO2max increased (p < 0.05) for HIITL training.
AtıfScopus9WoS9OpenAlex9İncele - Derleme MakaleAçık Erişim2024Scopus SJRQ3Meditative pathways to emotional intelligence in athletes: narrative review study
Aouani, Hajer; Selmi, Walid; Hammami, Achraf; Ceylan, Halil Ibrahim; Hammami, Raouf; Bayrakdaroglu, Serdar; Bayrakdaroglu, Yesim; Uluç, Ender Ali; Raul-Ioan, Muntean; Uluç, Sinem
Emotional intelligence, encompassing self-awareness, emotional regulation, empathy and social skills, holds pivotal importance in the pursuit of excellence for athletes. Meditation, represented by various forms such as mindfulness, loving-kindness, visualization, breath control and relaxation exercises, offers athletes a structured pathway to deepen self-awareness, enhance emotional regulation and foster empathy. In conclusion, meditation emerges not merely as a relaxation technique but as a transformative journey that empowers athletes to master their emotions, excel in sports, and enhance their overall well-being. This narrative literature review highlights the profound impact of meditation on athletes' emotional intelligence, encouraging further exploration in this evolving intersection of sports and mindfulness. In the demanding world of sports, emotional intelligence (EI) is a critical factor for athletes' success, encompassing self-regulation, empathy, communication and composure under pressure. Meditation, a transformative tool for deepening self-awareness, emotional regulation and mental resilience, has emerged as a promising avenue for cultivating EI in athletes. This narrative review synthesizes existing research and personal narratives to explore the interplay between meditation and EI in the context of sports. Evidence suggests that meditation can enhance EI through mindfulness, loving-kindness and visualization practices, promoting focus, stress management and emotional resilience. Integration of meditation into athletic training regimens offers athletes a competitive edge, sharpening their mental acuity and fostering supportive team dynamics. While the transformative potential of meditation for EI is substantiated by research, limitations such as the predominance of qualitative studies and case reports warrant further empirical investigations. Overall, this narrative review highlights the promising relationship between meditation, EI, and athletic performance, paving the way for future research and practical applications of mindfulness practices in the sports world.
AtıfScopus1WoS4OpenAlex1İncele - MakaleYayıncıda açık erişim2024Scopus SJRQ2Novel asymmetric biscarbothioamides as Alzheimer's disease associated cholinesterase inhibitors: synthesis, biological activity, and molecular docking studies
Muglu, Halit; Yakan, Hasan; Erdogan, Musa; Topal, Fevzi; Topal, Meryem; Turkes, Cuneyt; Beydemir, Sukru
Exploring novel frameworks for treating Alzheimer's disease is an ambitious objective. In this particular context, a range of asymmetric biscarbothioamide derivatives (3a-l) with varying substitutions have been meticulously designed and effectively synthesized. The newly synthesized compounds have all been definitively characterized using established spectroscopic techniques such as 1H-NMR, 13C-NMR, FT-IR, and elemental analysis. In vitro, all the derivatives (3a-l) were evaluated to assess their inhibitory potential against cholinesterase enzymes (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE). The outcomes demonstrated that these derivatives were potent and exhibited selectivity in inhibiting AChE, except for compounds 3b and 3e, which specifically inhibited BChE, showcasing varying degrees of KI values. Significantly, compounds 3j (KIs of 11.91 +/- 2.25 nM for AChE and 77.76 +/- 8.02 nM for BChE) and 3h (KIs of 14.73 +/- 2.30 nM for AChE and 59.54 +/- 6.20 nM for BChE) emerged as the most potent dual inhibitors of AChE and BChE within the series, respectively, with KI constants even lower than those of the standard drug tacrine (KIs of 68.70 +/- 5.39 nM for AChE and 111.60 +/- 10.52 nM for BChE). Furthermore, their potential scavenging activity against DPPH and ABTS radicals was evaluated. To further validate the experimental findings, molecular docking studies were performed in silico to ascertain the binding modes of these compounds with the active pockets of AChE and BChE enzymes. Investigating innovative frameworks for addressing Alzheimer's disease is a challenging goal. In this specific scenario, a selection of asymmetric biscarbothioamide derivatives (3a-l) with different substitutions has been carefully formulated and successfully synthesized.
AtıfScopus30WoS29OpenAlex32İncele - MakaleAçık Erişim2024Scopus SJRQ2Comparative analysis of Glasgow Coma Scale, quick Sepsis-related Organ Failure Assessment, base excess, and lactate for mortality prediction in critically ill emergency department patients
Meral, Gurbuz; Ardiç, Senol; Günay, Serkan; Güzel, Kadir; Köse, Ahmet; Durmus, Hulya Gencbay; Uysal, Serhat; Coskun, Aydin
OBJECTIVES: It is crucial to promptly identify high-mortality patients in emergency departments and initiate their treatment as soon as possible. Although many parameters have been studied to select patients with high mortality, no comprehensive evaluation exists in previous literature on these parameters in critically ill patients, regardless of patient groups. The aim of this study is to evaluate the Glasgow Coma Scale (GCS), quick Sepsis-related Organ Failure Assessment (qSOFA), blood gas base excess (BE), and blood gas lactate in predicting mortality in critically ill patients admitted to the emergency department. METHODS: This prospective observational cohort study included adult patients with Emergency Severity Index 1-2 (critically ill) admitted to the emergency department. All patients were evaluated by the physician within 10 min, and blood gas samples were taken. The data collection forms recorded the patients' GCS and qSOFA scores at the time of first evaluation by the physician. The qSOFA score assessment was performed in all patients with ESI levels 1 and 2, regardless of whether infective pathology was suspected. Blood gas BE and lactate values were also from laboratory test results. Patients or their relatives were contacted by phone at the end of the 1st month to obtain information about the clinical condition (survival or mortality). RESULTS: A total of 868 patients were included, with 163 deaths observed within 30 days. GCS score, qSOFA score, and lactate value were significant in predicting mortality within 30 days. While the BE value was significant for predicting 30-day mortality for values equal to or below the lower limit of -1.5 (P < 0.001), it was not significant for values equal to or above the upper limit of +3 (P > 0.05). The most successful prediction model for predicting 30-day mortality was found to be qSOFA with a cutoff value of >= 1. CONCLUSION: In emergency departments, each of the GCS, qSOFA scores, BE, and lactate values can be used independently as a practical mortality prediction model in critically ill patients. Among these four models, qSOFA is the most successful practical mortality prediction model in critically ill patients.
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