Yazarlar
- Uzun, Sevda(79)
- Kulakaç, Nurşen(40)
- Turan, Ibrahim(33)
- Demir, Selim(32)
- Türkkan, Tuğba(24)
- Aydin, Aydanur(23)
- Topal, Fevzi(22)
- Aliyazicioglu, Yuksel(21)
- Tuncer, Metin(21)
- Bayrakdaroglu, Serdar(19)
- Demirağ, Hatice(19)
- Hintistan, Sevilay(18)
- Topal, Meryem(18)
- Yılmaz, Coşkun(18)
- Bayrakdaroğlu, Serdar(15)
- Yilmaz, Coskun(15)
- Mentese, Ahmet(14)
- Reis, Hatice Catal(14)
- Demir Doğan, Melike(13)
- Emirza, Elif Güzide(13)
- Memetoglu, Mehmet Erdem(13)
- Tuncer, Gülsüm Zekiye(13)
- Bülbül, Kenan(12)
- Cin, Aynur(12)
- Düzgün, Azer Özad(12)
- Koçak, Tevfik(12)
- Odaci, Hatice(12)
- Oğuzhan, Hatice(12)
- Tonkaz, Duygu Erkal(12)
- Tonkaz, Mehmet(12)
- Turk, Veysel(12)
- Ceylan, Halil Ibrahim(11)
- Kilinc, Kagan(11)
- Köse, Aslı(11)
- Merdan, Mehmet(11)
- Acet, Tuba(10)
- Aksoy, Bahar(10)
- Aydin Sayilan, Aylin(10)
- Baltaci, Cemalettin(10)
- Deger, Orhan(10)
Yayınlar
- MakaleAçık Erişim2024Scopus SJRQ1Evaluation of Spiritual Care and Well-Being Levels of Individuals Diagnosed with Lung Cancer in Turkey
Çakmak, Seher; Demir Doğan, Melike; Selim, Nisanur; Kalleci, Gülse Nur
This study aimed to assess the spiritual care needs and spiritual well-being levels of lung cancer patients undergoing chemotherapy (CT). This descriptive cross-sectional study was conducted with 110 patients in the outpatient CT unit of a university hospital. Data were collected using a personal information form, the “Three-Factor Spiritual Well-Being Scale” and the “Spiritual Care Needs Scale.” The average age of participants was 62.6 ± 8.0 years. Patients with a university or above education level, civil servants, self-employed individuals, those receiving only CT, and those with less than 5 CT cycles had significantly higher spiritual well-being scores (p < 0.05). Spiritual care needs scale scores were significantly higher for married individuals and those receiving only CT (p < 0.05). In conclusion, both spiritual well-being levels and spiritual care needs were observed to be high among lung cancer patients.
AtıfScopus3WoS3OpenAlex3
İncele - Derleme MakaleYayıncıda açık erişim2024Scopus SJRQ1From Garden to Pillow: Understanding the Relationship between Plant-Based Nutrition and Quality of Sleep
Arslan, Neslihan; Bozkır, Eda; Koçak, Tevfik; Akin, Meleksen; Yilmaz, Birsen
The effect of diet on sleep quality has been addressed in many studies; however, whether/how plant-based diets (PBDs) impact sleep-related parameters has not been explored in detail. This review aims to give an overview of the components of PBDs and the possible mechanisms through which PBDs may improve sleep quality. Studies have indicated that diets such as PBDs, which are typically high in fruits, vegetables, nuts, seeds, whole grains, and fiber, are associated with better sleep outcomes, including less fragmented sleep and improved sleep duration. Several mechanisms may explain how PBDs impact and/or improve sleep outcomes. Firstly, PBDs are characteristically rich in certain nutrients, such as magnesium and vitamin B6, which have been associated with improved sleep patterns. Secondly, PBDs are often lower in saturated fats and higher in fiber, which may contribute to better overall health, including sleep quality. Additionally, plant bioactive compounds like phytochemicals and antioxidants in fruits, vegetables, and herbs may have sleep-promoting effects. According to available data, PBD and Mediterranean diet elements promise to enhance sleep quality; however, it is crucial to note that diets should be customized based on each person’s needs.
AtıfScopus20WoS17OpenAlex21İncele - MakaleAçık Erişim2024Scopus SJRQ1Improving brain tumor classification with combined convolutional neural networks and transfer learning
İncir, Ramazan; Bozkurt, Ferhat
Brain tumors pose a serious threat, causing the deaths of thousands of people worldwide, and can lead to life-threatening consequences when not accurately diagnosed. The classification of brain tumors and the determination of correct treatment strategies are crucial, yet this process encounters various challenges. These tumors originate from different cell types and exhibit diversity in growth rates, histological features, and genetic structures. Some may show similarities at the microscopic level, complicating classification and making diagnosis and treatment challenging. The examination of brain MR images is a widely used method in diagnosing brain tumors. However, occasional misdiagnosis of tumors can lead to ineffective responses to treatments and reduced chances of survival for patients. Traditional machine learning classifiers require manually determined features, which is quite time-consuming. On the other hand, deep learning is highly effective in feature extraction and has recently been widely preferred in classification. In this context, the effectiveness of transfer learning architectures in brain tumor diagnosis was evaluated. Six different transfer learning architectures, including ResNet-50, MobileNet, VGG16, Inception-V3, DenseNet-121, and EfficientNetV2-M, were used in this study. A public MRI dataset was used for model validation and comparison with similar studies. To address the imbalance in the number of images among classes in the dataset, data augmentation techniques such as random rotation were applied during data preprocessing. Experiments revealed that the EfficientNetV2-M model outperformed other architectures with a 98.01% accuracy rate. Additionally, the study aimed to create a new model with more comprehensive feature extraction and generalization ability by combining the advantages of multiple models in different combinations. In this context, combinations of EfficientNetV2-M architecture with Inception-V3 and DenseNet-121 architectures were formed. Through these combinations, a concatenation-based EfficientNetV2-M + Inception-V3 model achieved a 98.41% accuracy value. It was observed that the proposed concatenation-based model outperformed advanced methods in improving medical imaging techniques and patient outcomes.
AtıfScopus75WoS49OpenAlex67İncele - MakaleAçık Erişim2024Scopus SJRQ3Functional outcome and single hop test results of ACL reconstruction in athletes at a follow-up of 6 and 12 months: modified all-inside versus conventional hamstring autograft
Yoldaş, Burak; Yılmaz, Ali Kerim; Yılmaz, Coşkun; Akdemir, Enes; Anıl, Berna; Benli, Merve Demir; Genç, Ahmet Serhat; Kehribar, Lokman
Anterior cruciate ligament (ACL) tears are injuries with a high incidence in athletes, and ACL reconstruction (ACLR) is a surgical treatment orthopedists perform. This study aims to compare the 6 and 12 months post-op results of single leg hop tests (SLHT) performed in multidirectional conventional semitendinosus/gracilis (ST/G) and modified all inside (MAI) ACLR techniques on both sides and the limb symmetry indexes (LSI) of both techniques. This study evaluated a retrospective cohort of 50 male athletes who applied MAI (n = 23) and traditional ACLR ST/G (n = 27) techniques. Functional knee strength of the participants on both sides was measured with different SLHTs at 6 and 12 months postoperatively. The SLHT included medial side (MSTH), triple hop (TH), medial rotation (90◦) (MRH), crossover triple (CH) ve the single hop (SH) hop for distance. Both ACLR techniques showed significant improvement in mean Tegner, International Knee Documentation Committee (IKDC) and Lysholm scores preoperatively and at 6 and 12 months postoperatively (p < 0.05). For MAI and ST/G techniques, there was no significant difference in the results of SLHTs at 6 and 12 months for both the operated and non-operated sides (p < 0.05). Significance was found only in the MRH test of the non-operated side (p < 0.05). There was no significant difference in SLHT scores between the operated and non-operated sides at 6 and 12 months postoperatively (p > 0.05). There was no difference in LSI scores between techniques (p < 0.05). Our study revealed similar LSI rates in ST/G and MAI techniques at 6 and 12 months, suggesting that MAI technique can be used as a functional ACLR technique for athletes.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2024Scopus SJRQ3The Effect of Oral and Dental Health Status on the Self-Esteem Levels of Turkish University Youth
Alsaç, Selda Yüzer; Oztas, Gulay; Acar, Mukaddes Demir; Tuncay, Birgül; Coskun, Adnan Batuhan
Objectives: This study aimed to investigate the impact of oral and dental health status on the self-esteem levels of Turkish university youth. Methods: This descriptive cross-sectional study included a sample of 962 Turkish university youth, aged 16 - 24, who met all the study criteria during the 2020 - 2021 academic year. Data were collected using a questionnaire and the Rosenberg Self-Esteem Scale (RSES). The data were analyzed with SPSS version 23.0. T-tests were used for pairwise comparisons, and one-way ANOVA was used for multiple comparisons. Results: Among the students who participated in the study, 56.7% were found to have high self-esteem, with a mean RSES score of 1.69 ± 1.62. Statistically significant differences were found between the RSES score and several factors, including decayed teeth (P < 0.01), presence of halitosis (P < 0.01), tooth color (P < 0.01), crooked teeth (P = 0.045), and toothache (P = 0.008). It was determined that dental crookedness, decayed teeth, bad breath, dark yellow teeth, the presence of tooth fillings, and extracted teeth were negatively associated with self-esteem. However, no statistically significant differences were found between selfesteem and factors such as the presence of tooth fillings, extracted teeth, tooth brushing habits, frequency of dental visits, or snack food consumption (P > 0.05). Conclusions: The results of this study reveal that poor oral care negatively impacts individuals' self-esteem. Issues related to oral and dental health, particularly concerning the appearance and condition of teeth, affect young people's relationships and self-confidence in social environments. It is crucial to develop family and school education programs, as well as national policies, particularly during childhood and university years, when attitudes toward oral and dental health are being established.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2024Scopus SJRQ3Noise as a physical risk factor in furniture industry machines
Yasar, Sekip Sadiye; Komut, Osman; Yasar, Mehmet; Fidan, Muhammed Said
This study aimed to determine the risk level of noise, which is an important physical risk, in small and medium-sized furniture industry enterprises. The noise levels of the circular sawing machines, edge banding machines, and mitre cutting machines, which are among the main processing machines of the sector, were measured. The study was carried out in 32 furniture businesses. The possible risks of noise on the operators of the machines in question and other employees were evaluated. Noise level measurements were made with the help of TESTO 815 measuring device. Dunnett’s T3 test was used to detect differences in noise levels for machine operators and other employees. It was determined that the edge banding machine does not pose an occupational health and safety risk in terms of noise risk factors. However, the mitre cutting machine and the circular sawing machine pose a risk for the machine operator in active production by creating noise above the established exposure limit value. The mitre cutting machine carries the same risk for the machine operator when it is in operation but in passive production. The results revealed the need for personal protective equipment for machine operators for mitre cutting and circular sawing machine.
AtıfScopus2WoS1OpenAlex3İncele - MakaleAçık Erişim2024Determination of University Students’ Preventive Attitudes for Lung Cancer and Healthy Life Awareness and The Influencing Factors; [Üniversite Öğrencilerinin Akciğer Kanserinden Korunmaya Yönelik Tutum ve Sağlıklı Yaşam Farkındalıkları ile Etkileyen Faktörlerin Belirlenmesi]
Demir Doğan, Melike
Objective: This study was conducted to determine the attitudes of university students towards lung cancer screening and healthy lifestyle and the factors affecting these attitudes. Material and Method: In this descriptive cross-sectional study, data were collected from 295 students between September 2022 and February 2023 using personal information form, Healthy Living Awareness Scale, and Health Belief Model Scale for Lung Cancer and Screenings. Results: It was observed that the perception of sensitivity and perception of obstacle subscales of the Health Belief Model Scale for Lung Cancer and Screenings were higher in males than females, and those with extended families had higher perception of violence and perception of obstacle than those with nuclear families. Perception of sensitivity and perception of violence decreased as general health status improved. Sensitivity perception was higher in smokers compared to non-smokers. Health motivation was higher in non-smokers than smokers. In addition, perception of barrier was higher in alcohol consumers compared to non-consumers. As the awareness of healthy living increased, the perception of violence and perception of barrier subscales of the health belief model of lung cancer orientation decreased. Conclusion: Consequently, it was determined that the students perceived lung cancer screening as beneficial, but they were not sensitive enough to have screening. The barrier perception related to screening was low, the health motivation was high and the severity perception was moderate.
- MakaleAçık Erişim2024Scopus SJRQ1Psychosocial dimensions of being a child in women’s shelters: A phenomenological study on the experiences of battered women – A case study from Türkiye’s Northern Region
Uzun, Sevda; Emirza, Elif Güzide
Background: Violence against women has numerous devastating effects. Exposure to violence not only impacts women but also affects their children both physically and psychosocially. Aims: The study aimed to evaluate the psychosocial problems of children living with their mothers in women’s shelters from the mothers’ perspective with a phenomenological approach. Methods: Utilizing the phenomenological research method, semi-structured in-depth interviews were conducted with 14 individuals in a women’s shelter in a province in northern Türkiye. The criterion sampling method, a purposive sampling technique, was employed to select participants. Interviews continued until data saturation was achieved. All interviews were audio recorded and then transcribed, and thematic analysis was applied to analyze the data. The study adhered to the COREQ checklist for reporting. Results: The data analysis revealed four main categories (effects of violence on the mother, actions taken to protect children from violence, effects of violence and staying in a shelter on the child, and psychosocial needs for the protection of the child’s mental health in the shelter) and 10 sub-themes (psychological effects, physical effects, social effects, domestic actions, organizational actions, psychological effects, physical effects, social effects, support system, and coping). Conclusion: The study concluded that violence significantly impacted the mental, physical, and social well-being of both women and children, posing challenges to their ability to cope with the aftermath. Women exerted considerable effort in protecting their children from violence, and they needed psychosocial support to ensure the well-being of their children’s mental health during their stay in shelters.
AtıfScopus1WoS1OpenAlex2İncele - MakaleAçık Erişim2024Scopus SJRQ1Experiences of Turkish mothers of children with autism: a phenomenological study
Aktaş, Eda; Ustuner Top, Fadime; Uzun, Sevda
The study aimed to explore mothers’ experiences of children with autism using a phenomenological approach. Semi-structured, in-depth interviews were conducted with 18 parents with children attending a special education centre in a northern province of Turkey. Criterion sampling, a form of purposive sampling, was employed to select participants. Interviews continued until data saturation was achieved. All interviews were audio-recorded and transcribed verbatim. Thematic analysis was utilized to analyze the data, and the study adhered to the COREQ checklist for reporting qualitative research. As a result of analyses, three main themes (the process of diagnosis, the effect of the child’s illness on parents and their challenges over time, and considerations regarding the child’s educational journey) and eight sub-themes (feelings and thoughts, reflections on the causes, reactions encountered, emotional effects, social effects, physical effects, perception of social support, and expectations from the educator and the education process) emerged. The study concluded that mothers of children with autism are emotionally, physically, and socially impacted by their child’s condition, facing considerable challenges in coping. In light of these findings, it is recommended that policymakers in our country develop plans that address the difficulties expressed by participants, review and potentially enhance financial and social support for families, and consider increasing special education hours.
AtıfScopus5WoS5OpenAlex5İncele - MakaleAçık Erişim2024Scopus SJRQ1Fusion of transformer attention and CNN features for skin cancer detection
Reis, Hatice Catal; Turk, Veysel
Melanoma is a skin cancer that spreads quickly and has serious risks. Early diagnosis is essential, but since the symptoms of skin lesions in the early stages are vague and similar, they can be difficult for specialists to detect. Therefore, machine learning-based alternative diagnostic methods can be developed in addition to existing ones. This study proposes a new deep learning model, a modified lightweight vision transformer (ViT) architecture, and a hybrid framework developed with an integrated deep learning model and an Ensemble Learning (EL) model for the early-stage diagnosis of skin lesions. The proposed deep learning model was developed based on convolution layers and transformers. The model is called multi-head attention block depthwise separable convolution network (MABSCNET). The proposed hybrid framework was developed by combining modern deep learning and EL models pre-trained with the ImageNet dataset along with the MABSCNET model. In the experimental process, the effectiveness of the proposed methods was evaluated on the ISIC 2020 dataset. Additionally, additional experiments were conducted on ISIC 2018 and a Kaggle dataset to analyze the proposed hybrid framework's classification performance. Image enhancement techniques were used in the datasets. In the ISIC 2020 dataset, the MABSCNET model reached 78.63 % accuracy, the ViT model obtained 76.50 %, and the hybrid framework reached 92.74 % accuracy. Moreover, the proposed hybrid framework achieved 100 % on the ISIC 2018 dataset and 94.24 % on the Kaggle dataset.
AtıfScopus62WoS37OpenAlex51İncele - MakaleAçık Erişim2024Scopus SJRQ2Determining the health-seeking behaviors of people with epilepsy
Bingöl, Nuray; İşcan Ayyildiz, Neşe; Aktepe Coşar, Dilan
Purpose: Health-seeking behaviors of individuals who have epilepsy might affect the treatment of the disease, recovery process, and self-care activities. The present study was conducted to determine the health-seeking behaviors of individuals who have epilepsy. Materials and methods: The present study was conducted in a descriptive and cross-sectional design with 190 epilepsy patients who applied to the Neurology Clinic in the north and east of Turkey between April 2023 and January 2024. The data of the study were collected by using the Introductory Data Form, Health-Seeking Behavior Scale (HSBS). The IBM SPSS 27 software, variance analysis, Tamhane T2, ANOVA Test, Tukey Test, and Multiple Regression Analysis were used to evaluate the study data. Results: The mean score of the online health-seeking behavior sub-dimension of the Health-Seeking Behavior Scale of the individuals who had epilepsy was found to be 13.32 ± 5.40, the mean score of the professional health-seeking behavior sub-dimension was 9.92 ± 2.75, and the mean score of the traditional health-seeking behavior sub-dimension was 8.46 ± 3.29. No significant differences were detected between individuals’ sex, seizure types, and health-seeking behaviors, and a significant difference was detected between marital status, educational status, place of residence, occupation, income level, seizure frequency, and medication use status and health-seeking behaviors (p < 0.05). According to the multiple linear regression analysis that was used to examine the effects of sociodemographic characteristics of individuals with epilepsy on health seeking behavior scale scores, it was found that sociodemographic characteristics such as educational status, place of residence, marital status, and age significantly affected online, professional, and traditional health seeking behavior scores. Conclusion: In conclusion, it was found in the present study that the online health-seeking behavior of the individuals who had epilepsy was higher than other health-seeking behaviors. The health-seeking behaviors of patients were affected by sociodemographic characteristics (e.g., marital status, educational status, place of residence, occupation, income level, seizure frequency, and medication use). It is of great importance to conduct larger future studies on individuals who have epilepsy and are seeking traditional treatment for epileptic seizures because the sources from which health information is obtained might affect the diagnosis, treatment, and recovery processes.
AtıfScopus4WoS5OpenAlex5İncele - MakaleYalnız künye2024Attitudes of Individuals with a Family History of Hypertension Towards the Prevention of Hypertension and Health Locus of Control
Demir Doğan, Melike; Akdemir, Rabia Rumeysa
This study was conducted to determine the attitudes of individuals with a family history of hypertension towards the prevention of hypertension, their health locus of control, and the factors affecting these attitudes. The data of this cross-sectional study were collected from 97 individuals through face-to-face interviews between 01 March 2023 and 01 June 2023. A Descriptive Information Form, the Attitudes Scale Towards Prevention of Hypertension, and the Multidimensional Health Locus of Control Scale-Form A were used to collect data. It was observed that the participants had a high level of attitudes towards prevention of hypertension. Their knowledge of disease and risk, habits and lifestyle attitudes, attitudes towards prevention and control, and attitudes towards mental state and physical activity were positively high. Those who lived with their families had lower attitudes towards the prevention of hypertension, attitudes towards prevention and control, and knowledge of disease and risk than those who lived alone. Smokers had lower attitudes towards habits and lifestyles than non-smokers. As age advanced, attitudes towards the prevention of hypertension, attitudes towards prevention and control, and attitudes towards habits and lifestyles rose. Attitudes towards prevention and control declined as educational levels elevated. As educational level elevated, knowledge of disease and risk declined. It was found that the locus of control of the individuals was the internal locus of control, and as the internal locus of control grew, their attitudes towards the prevention of hypertension, attitudes of prevention and control, knowledge of disease and risk, attitudes of mental state and physical activity, and attitudes of habit and lifestyle positively increased.
AtıfScopus1OpenAlex1İncele - MakaleYalnız künye2024Scopus SJRQ1Identification of wart treatment evaluation by using optimum ensemble based classification techniques
Balcı, Muharrem; Alkan, Ahmet
Warts caused by Human Papilloma Virus (HPV) do not disappear spontaneously with the body's natural immunity. This is due to many features of HPV, such as its weak immune effect, not entering the bloodstream and causing an immune response, and permanent infection of skin cells. HPV requires urgent treatment due to these characteristics and the fact that warts are most common on the hands and feet and are painful and disturbing. Choosing the most appropriate Cryotherapy or Immunotherapy treatment methods according to the patient's physiological characteristics is important in order to carry out the treatment process quickly. This study focuses on helping experts choose the most appropriate treatment for the most common plantar and common warts. For the selection of treatment method machine learning have been used. Bagged Tree and Subspace K-Nearest Neighbors (KNN) Ensemble classification algorithms were developed and tested on two data sets. These data sets were used to develop classification algorithms with pre- and post-treatment information of 180 patients receiving cryotherapy and immunotherapy treatments. The Subspace KNN Ensemble algorithm correctly predicted the treatment results of 88 of 90 patients receiving cryotherapy treatment, reaching 97.80% accuracy, and the Bagged Tree Ensemble algorithm correctly predicted 78 out of 90 patients receiving immunotherapy, reaching 86.7% accuracy. It has been shown that algorithms can help experts in terms of both high accuracy values and fast decision making. The algorithms proposed have not been used before, and it has also been seen that they have superior performances than similar studies.
AtıfScopus31WoS30OpenAlex36İncele - MakaleAçık Erişim2024Scopus SJRQ3Sprint and Anaerobic Power with the Soccer-Specific ACTN3 Gene: A Distintive Example; [Sprint y Potencia Anaeróbica con el Gen ACTN3 Específico del Fútbol: Un Ejemplo Distintivo]
Söyler, Mehmet; Zileli, Raif; Özkamçı, Hüseyin; Diker, Gürkan; Sever, Mehmet Onur; Bayrakdaroglu, Serdar; Ön, Sadi; Can, Ibrahim; Ulucan, Korkut; Aslan, Beste Tacal
The aim of this study is twofold: (1) to identify differences in certain anaerobic parameters (10m sprint, 30m sprint, anaerobic power, and Illinois agility tests) between professional and amateur soccer players, and (2) to determine whether there is a difference in the ACTN3 gene polymorphism between professional and amateur soccer players. Ultimately, the goal is to reveal which parameters contribute to the differentiation in these two aspects. A total of 133 volunteer soccer players, including 71 professionals and 62 amateurs, participated in the research. DNA extraction from buccal epithelial cells was performed using a commercial kit to determine the genetic background of the athletes, and Real-Time PCR was conducted for genotyping. Statistical analysis of the findings obtained from the test results was performed using the SPSS 23 (SPSS Inc., Chicago, IL, USA) package program. The homogeneity of variance of the data was assessed using the Levene Test, and normal distribution analyses were conducted using the Shapiro-Wilk Test. Chi-square and Mann-Whitney U tests were employed for parameter analysis. The significance level was set at p<0.05. Evaluation of the data in our study revealed no statistically significant difference in ACTN3 rs1815739 gene polymorphism between the groups (p>0.05). However, there is a statistically significant difference in anaerobic parameters (10m sprint, 30m sprint, and anaerobic power) except for the Illinois test (p<0.05). In conclusion, our study found that gene polymorphism is not a differentiating factor between professional and amateur soccer players, but speed (10m and 30m) and anaerobic power parameters are differentiating factors.
AtıfScopus1İncele - MakaleYalnız künye2024Scopus SJRQ2The effect of nonpharmacological interventions applied by nurses to intensive care patients on the duration of delirium: a meta-analysis study
Söylemez, Gönül Kara; Uzun, Sevda
Objective: It was aimed to determine the effect level of nonpharmacological methods applied by nurses to patients hospitalized in the intensive care unit on the duration of delirium. Materials and methods: For this study, relevant studies were accessed by searching in July–October 2022. After the necessary exclusions were made, 14 studies were included in the study. The total sample size of the studies was 1123. Results: According to the results, nonpharmacological interventions applied by nurses to intensive care patients were found to reduce the duration of delirium (SMD: − 0.625, 95% CI: − 1.1040–0.210; Z = − 2.950, p = 0.003, I2 = 93.119%). The country of the study (SMD: − 0.047, p = 0.001) and the types of nonpharmacological interventions used (SMD: − 0.062, p = 0.000) influenced the effect size of modulators on the duration of delirium in ICU patients. Conclusion: Nonpharmacological interventions applied by nurses, who have significant responsibilities in the protection and promotion of health, were found to reduce the duration of delirium in intensive care patients. This study shows that nurses, one of the main components of the multidisciplinary team in intensive care, are successful when they apply nonpharmacological interventions well.
AtıfScopus6WoS6OpenAlex6İncele - MakaleYalnız künye2024Scopus SJRQ1Effect of Lavender Oil on Preoperative Anxiety: Systematic Review and Meta-analysis
Kulakaç, Nurşen; Sayılan, Aylin Aydın
Purpose: Surgical interventions are known to induce anxiety in patients due to the associated risks and potential complications. Various methods are employed to alleviate preoperative anxiety. This study aimed to investigate the impact of lavender oil application on the anxiety levels of patients scheduled for surgical procedures. Design: Systematic review and meta-analysis. Methods: Studies were accessed using the keywords “preoperative and lavender oil and stress” in Turkish and English between July 1 and 30, 2022, through PubMed (including MEDLINE), Cochrane, EBSCOhost, Web of Science, YÖK National Thesis Center, and Google Scholar. The standardized mean difference was calculated using random-effects models, and the Cochrane Collaboration tool was used to assess the risk of bias in each study. The study was prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis checklist. Findings: Twenty studies were included in the analysis. The anxiety level of the experimental group to which lavender oil was applied before the surgical intervention was significantly lower than that of the control group (standardized mean difference:−5.40; 95% CI: −8.76 to −2.04). Conclusion: Preoperative lavender oil application was found to be an effective method for relieving patients’ anxiety. Lavender oil is thought to be a potential standalone treatment for preoperative anxiety.
AtıfScopus6WoS5OpenAlex7İncele - MakaleAçık Erişim2024Scopus SJRQ2Operating room and surgical team members scheduling: A comprehensive review
Aktaş, Esra; Atmaca, Hatice Ediz; Akbulut, Hatice Erdoğan
Operating rooms (OR) are one of the most expensive parts of a hospital with complex processes, and the efficient use of resources is of utmost importance. Therefore, proper management and operation of operating rooms are extremely crucial. OR scheduling ensures that the surgeries are performed at the proper time, patients are treated effectively and safely, resources are used effectively, and staff is increased in work efficiency. Furthermore, accurately scheduled surgeries are safer for patients' healing processes. This is dependent on factors such as the availability of qualified personnel at the appropriate time, the readiness of surgical equipment, and the pro-vision of proper sterilization and hygienic conditions. Surgical team scheduling ensures that surgeries begin on time, are completed effectively, and patients are treated safely. It is also critical to reduce employee fatigue and balance the workload. As a result, integrating surgical teams into operating room scheduling problems provides significant benefits. Accordingly, 29 research articles focusing on the problem of OR scheduling, within the scope of constraints on surgical team members, scheduling strategies, uncertainties, and solution methods, are thoroughly re-viewed in this study.
AtıfScopus7WoS6OpenAlex8İncele - MakaleYalnız künye2024Scopus SJRQ3Assessment of Anticholinergic and Antidiabetic Properties of Some Natural and Synthetic Molecules: An In Vitro and In Silico Approach
Çomaklı, Veysel; Aygül, İmdat; Sağlamtaş, Rüya; Kuzu, Müslüm; Demirdağ, Ramazan; Akincioğlu, Hülya; Adem, Şevki; Gülçin, İlhami
Introduction: This study aimed to determine the in vitro and in silico effects of some natural and synthetic molecules on acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and α-glucosidase enzymes. Background: Alzheimer's disease (AD) and Type II diabetes mellitus (T2DM) are considered the most important diseases of today’s world. However, the side effects of therapeutic agents used in both diseases limit their use. Therefore, developing drugs with high therapeutic efficacy and better pharmacological profile is important. Objectives: This study sets out to determine the related enzyme inhibitors used in treating AD and T2DM, considered amongst the most important diseases of today’s world. Methods: In the current study, the in vitro and in silico effects of dienestrol, hesperetin, L-thyroxine, 3,3',5-Triiodo-L-thyronine (T3) and dobutamine molecules on AChE, BChE and α-glycosidase enzyme activities were investigated. Results: All the molecules showed an inhibitory effect on the enzymes. The IC50 and Ki values of the L-Thyroxine molecule, which showed the strongest inhibition effect for the AChE enzyme, were determined as 1.71 µM and 0.83 ± 0.195 µM, respectively. In addition, dienestrol, T3, and dobutamine molecules showed a more substantial inhibition effect than tacrine. The dobutamine molecule showed the most substantial inhibition effect for the BChE enzyme, and IC50 and Ki values were determined as 1.83 µM and 0.845 ± 0.143 µM, respectively. The IC50 and Ki values for the hesperetin molecule, which showed the strongest inhibition for the α-glycosidase enzyme, were determined as 13.57 µM and 12.33 ± 2.57 µM, respectively. Conclusion: According to the results obtained, the molecules used in the study may be considered potential inhibitor candidates for AChE, BChE and α-glycosidase.
AtıfScopus8WoS7OpenAlex8İncele - MakaleYalnız künye2024Scopus SJRQ2The Impact of Video-Based Simulation Training on Perioperative Process in Nursing Students: A Randomized Controlled Study
Kulakaç, Nurşen; Koçan, Sema; Aktuğ, Cemile
This study was conducted to explore the effect of video-based simulation training on postoperative patient care, clinical decision-making, and the competency levels of nursing students. The study was conducted as a randomized controlled trial. The sample of the study consisted of students (n=87) attending the nursing department of the health sciences faculty of a state university located in the Eastern Black Sea Region of Turkey. The data were collected with the “Student Information Form”, the “Postoperative Patient Care Knowledge Test”, the “Clinical Decision-Making in Nursing Scale (CDMNS)”, and the “Competency Inventory of Nursing Students (CINS)”. The postoperative patient care knowledge test scores of the experimental group students were statistically significantly higher than those of the control group (p<0.001). The CDMNS scores of the experimental group students were statistically significantly higher than those of the control group (p=0.024). There was no statistically significant difference between the CINS scores of the experimental and control groups. The results showed that the use of video simulation contributed positively to students' postoperative patient care and clinical decision-making.
AtıfScopus6WoS6OpenAlex7İncele - MakaleAçık Erişim2024Scopus SJRQ1Chemical Content by LC–MS/MS, Antiglaucoma, and Antioxidant Activity of Propolis Samples From Different Regions of Türkiye
İzol, Ebubekir; Bursal, Ercan; Yapıcı, İsmail; Abdullah Yilmaz, Mustafa; Yilmaz, İsa; Gülçin, İlhami
Propolis is a sticky substance produced by bees because of the reaction of beeswax, pollen, and bee enzymes. Particularly, their biological activity and chemical content attract attention. Thus, in this study, the total amount of phenolic and flavonoid substances, Fe3+-Fe2+, Cu2+ (cupric ions reducing activity [CUPRAC]), and Fe3+-TPTZ (ferric ions reducing antioxidant power [FRAP]) reducing, and DPPH• and ABTS•+ scavenging assays in vitro antioxidant properties of propolis samples obtained from four different provinces of Türkiye were determined. In addition, the chemical content of propolis samples was quantitatively determined by LC–MS/MS, and the antiglaucoma property was revealed by hCAII enzyme inhibition. Propolis samples from Ordu presented the highest amounts of total phenolic and flavonoid content (492.3 ± 5.8 and 96.1 ± 2.1, respectively) and also highest antioxidant activity (DPPH• and ABTS•+ IC50 [μg/mL]: 8.884 ± 0.84 and 4.589 ± 0.80, respectively; Fe+3, CUPRAC, and FRAP: 1.051 ± 0.012, 1.021 ± 0.008, and 0.957 ± 0.007 μg/mL, respectively). hCAII enzyme inhibition was highest in Muş propolis (IC50 [μg/mL]: 8.6) as determined. By LC–MS/MS, 53 different components were screened and 35 bioactive components were determined. According to the results, propolis was found to be a raw material because it contains high concentrations of acacetin, chrysin, caffeic acid, and quinic acid (123.824, 24.759, 47.779, and 16.32 mg analyte/g extract, respectively).
AtıfScopus15WoS15OpenAlex17İncele
