Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Demir, Selim(9)
- Turan, Ibrahim(7)
- Aliyazicioglu, Yuksel(6)
- Bostan, Sedat(6)
- Demir, Sertaç Timur(6)
- Mentese, Ahmet(5)
- Aliyazicioglu, Rezzan(4)
- Ashyralyyev, Charyyar(4)
- Dokuz, Abdurrahman(4)
- Simsek, Cemaleddin(4)
- Sipahi, Ferkan(4)
- Somuncuoğlu, Seda Özsoy(4)
- Vural, Alaaddin(4)
- Yaman, Serap Ozer(4)
- Öztürk, S.(4)
- Adanur, S.(3)
- Akpinar, Ozlem(3)
- Aksakal, Vecihi(3)
- Albayrak, Cenk(3)
- Cengiz, Selim(3)
- Deger, Orhan(3)
- Eker, Çiğdem Saydam(3)
- Gümrük, Recep(3)
- Güzel, Melıh(3)
- Kandemir, Raif(3)
- Karahan, Selim(3)
- Karsli, Orhan(3)
- Kayhan, Mustafa(3)
- Kilinc, Kagan(3)
- Kiremitçi, Ferdi(3)
- Korucuk, Selçuk(3)
- Küçük, Murat(3)
- Kılıç, Taşkın(3)
- Maden, N.(3)
- Misir, Sema(3)
- Peker, Osman(3)
- Sirat, Abdulveli(3)
- Sukuroglu, Ebru Emine(3)
- Tatli, Yasemin(3)
- Tosunoğlu, Büşra(3)
Yayınlar
- MakaleAçık Erişim2017Scopus SJRQ1Diversity and genetic analysis through DArTseq in common bean (Phaseolus vulgaris L.) germplasm from Turkey
Nemlı, Seda; Kaygisiz Aşçioğul, Tansel; Ateş, Duygu; Eşıyok, Dursun; Tanyolaç, Muhammed Bahattin
The common bean (Phaseolus vulgaris L.) is the most consumed food legume in the world and is a major source of dietary protein, carbohydrates, and valuable micronutrients, especially in developing countries. Diversity Arrays Technology (DArTseq), based on genome reduction with restriction enzymes, provides a rapid, high-throughput, and cost-effective tool capable of generating thousands of genotyped single nucleotide polymorphisms (SNPs) for a genome-wide analysis of genetic diversity. In this study, we aimed to characterize common bean accessions using SNPs detected by a DArTseq approach. A total of 43,018 SNPs were identified from 173 common bean accessions, including Andean and Mesoamerican genotypes. After filtering raw and redundant data, a total of 16,366 SNPs were considered for further analyses. According to population structure analysis, the genotypes were roughly divided into 2 gene pools of Andean and Mesoamerican types. Pairwise fixation index (Fst) values were calculated to resolve the differentiation between populations. This study demonstrated that discovering SNPs from the whole genome is a potential resource for identifying naturally diverse accessions and also the information could be used in breeding programs to develop new common bean varieties.
AtıfScopus19WoS18OpenAlex24TR Dizin3
İncele - MakaleYalnız künye2017Scopus SJRQ1Zircon Lu-Hf isotope systematics and U–Pb geochronology, whole-rock Sr-Nd isotopes and geochemistry of the early Jurassic Gokcedere pluton, Sakarya Zone-NE Turkey: a magmatic response to roll-back of the Paleo-Tethyan oceanic lithosphere
Karsli, Orhan; Dokuz, Abdurrahman; Kandemir, Raif
The early Mesozoic was a critical era for the geodynamic evolution of the Sakarya Zone as transition from accretion to collision events in the region. However, its complex evolutionary history is still debated. To address this issue, we present new in situ zircon U–Pb ages and Lu-Hf isotope data, whole-rock Sr-Nd isotopes, and mineral chemistry and geochemistry data of plutonic rocks to better understand the magmatic processes. The Gokcedere pluton is mainly composed of gabbro and gabbroic diorite. LA-ICP-MS zircon U–Pb dating reveals that the pluton was emplaced in the early Jurassic (177 Ma). These gabbros and gabbroic diorites are characterized by relatively low SiO2 content of 47.09 to 57.15 wt% and high Mg# values varying from 46 to 75. The samples belong to the calc-alkaline series and exhibit a metaluminous I-type character. Moreover, they are slightly enriched in large ion lithophile elements (Rb, Ba, Th and K) and light rare earth elements and depleted in high field strength elements (Nb and Ti). Gabbroic rocks of the pluton have a depleted Sr-Nd isotopic composition, including low initial 87Sr/86Sr ranging from 0.705124 to 0.705599, relatively high εNd (t) values varying from 0.1 to 3.5 and single-stage Nd model ages (TDM1 = 0.65–0.95 Ga). In situ zircon analyses show that the rocks have variable and positive εHf (t) values (4.6 to 13.5) and single-stage Hf model ages (TDM1 = 0.30 to 0.65 Ga). Both the geochemical signature and Sr-Nd-Hf isotopic composition of the gabbroic rocks reveal that the magma of the studied rocks was formed by the partial melting of a depleted mantle wedge metasomatized by slab-derived fluids. The influence of slab fluids is mirrored by their trace-element characteristics. Trace-element modeling suggests that the primary magma was generated by a low and variable degree of partial melting (~5–15%) of a depleted and young lithospheric mantle wedge consisting of phlogopite- and spinel-bearing lherzolite. Heat to melt the mantle material was supplied by the ascendance of a hot asthenosphere triggered by the roll-back of the Paleo-Tethyan oceanic lithosphere. The rising melts were accompanied by fractional crystallization and encountered no or minor crustal contamination en route to the surface. Taking into account these geochemical data and integrating them with regional geological evidence, we propose a slab roll-back model; this model suggests that the Gokcedere gabbroic pluton originated in a back-arc extensional environment associated with the southward subduction of the Paleo-Tethyan oceanic lithosphere during the early Jurassic period. Such an extensional event led to the opening of the northern branch of the Neotethys as a back-arc basin. Consequently, we conclude that the gabbroic pluton was related to intensive extensional tectonic events, which peaked during the early Jurassic in response to the roll-back of Paleo-Tethyan oceanic slab in the final stage of oceanic closure.
AtıfScopus68WoS64OpenAlex68İncele - MakaleYalnız künye2017Scopus SJRQ1System identification of arch dam model strengthened with CFRP composite materials
Altunisik, A.C.; Gunaydin, M.; Sevim, B.; Adanur, S.
This paper presents the structural identification of an arch dam model for the damaged, repaired and strengthened conditions under different water levels. For this aim, an arch dam-reservoir-foundation model has been constructed. Ambient vibration tests have been performed on the damaged, repaired and strengthened dam models for the empty reservoir (0 cm), 10 cm, 20 cm, 30 cm, 40 cm, 50 cm and full reservoir (60 cm) water levels to illustrate the effects of water levels on the dynamics characteristics. Enhanced Frequency Domain Decomposition Method in the frequency domain has been used to extract the dynamic characteristics. The dynamic characteristics obtained from the damaged, repaired and strengthened dam models show that the natural frequencies and damping ratios are considerably affected from the varying water level. The maximum differences between the frequencies for the empty and full reservoir are obtained as 16%, 33%, and 25% for damaged, repaired and strengthened model respectively. Mode shapes obtained from the all models are not affected by the increasing water level. Also, after the repairing and strengthening implementations, the natural frequencies of the arch dam model increase significantly. After strengthening, between 46-92% and 43-62% recovery in the frequencies are calculated for empty and full reservoir respectively. Apparently, after strengthening implementation, the mode shapes obtained are more acceptable and distinctive compared to those for the damaged model.
AtıfScopus11WoS10OpenAlex4İncele - MakaleYalnız künye2017Scopus SJRQ2Radioactivity measurements and risk assessments of spa waters in some areas in Turkey
Duran, Selcen Uzun; Kucukomeroglu, Belgin; Damla, Nevzat; Taskin, Halim; Celik, Necati; Cevik, Uğur; Ersoy, Hakan
The current study presents the results of the activity of radionuclides in spa waters, and evaluates their radiological influences on the population consuming these waters in the Central and Eastern Black Sea regions of Turkey. Since these waters are used for therapy and consumption purposes unconsciously, their radiological impact on the people was computed by taking into consideration the annual intake through ingestion of 226Ra, 232Th, 40K, 137Cs and 222Rn. The mean activities were estimated to be 11.35 for gross alpha, 6.23 for gross beta, 2.96 for 226Ra, 0.42 for 232Th, 0.069 for 137Cs, 0.19 for 40K, and 267 Bq L–1 for 222Rn, respectively. The estimated effective doses from spa water were found to be 49.77 µSv a–1 (226Ra), 5.95 µSv a–1 (232Th), 0.07 µSv a–1 (137Cs), 0.83 µSv a–1 (40K) and 56.03 µSv a–1 (222Rn). These values were evaluated and compared with related verified values from literature. Also, physico-chemical characterizations of spa water samples considered in the current study were investigated. This study would be useful for consumers and official authorities for the assessment of radiation exposure risk due to usage of the considered spa waters.
AtıfScopus10WoS10OpenAlex12
İncele - MakaleYalnız künye2017Scopus SJRQ4An integrated intuitionistic fuzzy set and mathematical programming approach for an occupational health and safety policy
Efe, Burak; Kurt, Mustafa; Efe, Ömer Faruk
This paper aims to establish an occupational health and safety policy for three firms. This paper provides to overcome the drawbacks of traditional FMEA (failure mode and effects analysis) by using an integrated intuitionistic fuzzy multi-criteria decision making method and a linear programming. Priority value of criteria has been defined by utilizing intuitionistic fuzzy analytic hierarchy process method and the highest risky failure mode among failure modes has been found by utilizing intuitionistic fuzzy VIKOR (VIsekriterijumska optimizacija i KOm-promisno Resenje). The application of risk evaluation is conducted to show the effectiveness of the proposed method in three firms. The reliability of the risk ranking is verified by helping of a sensitivity analysis and the advantages of the proposed approach are shown by comparing with the other methods. The managers of the firm present some limitations for the occupational health and safety policy so that these constraints are solved by helping of a linear programming. The results show that destroying of the existing steel ropes during production of plaster, risks that caused from work equipment and electric shock during cutting were determined the highest risky failure modes for construction, textile and metal firms, respectively.
AtıfScopus29WoS27İncele - MakaleAçık Erişim2017Scopus SJRQ1Production of deep-fried corn chips using stale bread powder: Effect of frying time, temperature and concentration
Yuksel, Ferhat; Karaman, Safa; Gurbuz, Melek; Hayta, Mehmet; Yalcin, Hasan; Dogan, Mahmut; Kayacier, Ahmed
In this study, utilization of stale bread powder was evaluated to produce low fat snack food formulation and for this purpose, corn chips were manufactured using stale bread at different concentrations. Response surface modeling technique was used to study the simultaneous effects of stale bread level (0–50%), frying time (40–60 s) and frying temperature (170–190 °C) on some physicochemical, textural and sensory properties of corn chips enriched with stale bread powder. Also, optimization of processing variables was performed for desired products. Results indicated that the addition of stale bread into the formulation decreased the oil content of the final product up to addition of 25% stale bread level. The hardness and yellowness of samples decreased with the increasing of stale bread level; while, the dry matter and ash contents as well as firmness value and sensory scores of samples increased with the increasing stale bread level. Generally, corn chips produced with the addition of stale bread were more preferred by the panel compared to control samples.
AtıfScopus20WoS17OpenAlex22İncele - MakaleAçık Erişim2017Scopus SJRQ2Solution of conformable fractional ordinary differential equations via differential transform method
Ünal, Emrah; Gökdoğan, Ahmet
Recently, a new fractional derivative called the conformable fractional derivative is given which is based on the basic limit definition of the derivative in (Khalil et al., 2014). Then, the fractional versions of chain rules, exponential functions, Gronwall's inequality, integration by parts, Taylor power series expansions is developed in (Abdeljawad, 2015). In this paper, we give conformable fractional differential transform method and its application to conformable fractional differential equations.
AtıfScopus134WoS116OpenAlex140İncele - MakaleYalnız künye2017Scopus SJRQ2Assessment of effect of material properties on seismic response of a cantilever wall
Cakir, Tufan
Cantilever retaining wall movements generally depend on the intensity and duration of ground motion, the response of the soil underlying the wall, the response of the backfill, the structural rigidity, and soil-structure interaction (SSI). This paper investigates the effect of material properties on seismic response of backfill-cantilever retaining wall-soil/foundation interaction system considering SSI. The material properties varied include the modulus of elasticity, Poisson’s ratio, and mass density of the wall material. A series of nonlinear time history analyses with variation of material properties of the cantilever retaining wall are carried out by using the suggested finite element model (FEM). The backfill and foundation soil are modelled as an elastoplastic medium obeying the Drucker-Prager yield criterion, and the backfill-wall interface behavior is taken into consideration by using interface elements between the wall and soil to allow for de-bonding. The viscous boundary model is used in three dimensions to consider radiational effect of the seismic waves through the soil medium. In the seismic analyses, North-South component of the ground motion recorded during August 17, 1999 Kocaeli Earthquake in Yarimca station is used. Dynamic equations of motions are solved by using Newmark’s direct step-by-step integration method. The response quantities incorporate the lateral displacements of the wall relative to the moving base and the stresses in the wall in all directions. The results show that while the modulus of elasticity has a considerable effect on seismic behavior of cantilever retaining wall, the Poisson’s ratio and mass density of the wall material have negligible effects on seismic response.
AtıfScopus11WoS12OpenAlex7İncele - MakaleAçık Erişim2017Scopus SJRQ2Prevalence and comparing of some microbiological properties, somatic cell count and antibiotic residue of organic and conventional raw milk produced in Turkey
Ürkek, Bayram; Şengül, Mustafa; Erkaya, Tuba; Aksakal, Vecihi
The aim of this study was to investigate the effects of production systems and milk collection periods on the somatic cell count (SCC), some microbiological properties, total aerobic mesophilic bacteria (TAMB), coliform, Staphylococcus aureus (S. aureus), yeast and mould) and antibiotic residue of milk; in Turkey. Milk samples were collected from 9 conventional farms and 9 organic farms during one year time, at six different months (December 2013 to October 2014), and all farms were selected from the same geographical locations. All organically managed farms had organic production certificates given by the Republic of Turkey Ministry of Food, Agriculture and Livestock. The count of TAMB, coliform, and coagulase positive S. aureus were affected by production systems at the level of p<0.01; yeast and mold, and somatic cell count (SCC) were affected at the level of p<0.05. But, differences according to months were statistically significant only on TAMB (p<0.01) and coliform (p<0.05) counts. The general means of TAMB, coliform and yeast and mould counts of the organic milk (OM) were significantly lower (p<0.05), while the general means of SCC and coagulase positive S. aureus count of the OM was significantly higher (p<0.05) compared to conventional milk (CM). Antibiotic residue was determined in one of the CM sample and in two of the OM samples. Our study is the first research that compared conventional and organic milk in Turkey. This study indicated that the microbiological quality of OM was the higher in terms of TAMB, coliform and yeast and mould, whereas was the lower in relation to SCC and coagulase positive S. aureus counts. But, the quality of both milk types should be improved.
AtıfScopus10WoS8OpenAlex12İncele - MakaleAçık Erişim2017Scopus SJRQ2Synthesis of imine bond containing insoluble polymeric ligand and its transition metal complexes, structural characterization and catalytic activity on esterification reaction
Gönül, İlyas; Ay, Burak; Karaca, Serkan; Saribiyik, Oguz Yunus; Yildiz, Emel; Serin, Selahattin
In this study, synthesis of insoluble polymeric ligand (L) and its transition metal complexes [Cu(L) Cl2]·2H2O (1), [Co(L)Cl2(H2O)2] (2) and [Ni(L)Cl2(H2O)2] (3), having the azomethine groups, were synthesized by the condensation reactions of the diamines and dialdehydes. The structural properties were characterized by the analytical and spectroscopic methods using by elemental analysis, Fourier Transform Infrared, Thermo Gravimetric Analysis, Powder X-ray Diffraction, magnetic susceptibility and Inductively Coupled Plasma. The solubilities of the synthesized polymeric materials were also investigated and found as insoluble some organic and inorganic solvents. Additionally, their catalytic performance was carried out for the esterification reaction of acetic acid and butyl acetate. The highest conversion rate is 75.75% by using catalyst 1. The esterification of butanol gave butyl acetate with 100% selectivity.
AtıfScopus4WoS4OpenAlex7İncele - MakaleYalnız künye2017Scopus SJRQ1Determination of optimum ejector operating pressures for anodic recirculation in SOFC systems
Genc, Omer; Toros, Serkan; Timurkutluk, Bora
In this study, a numerical analysis of an ejector for micro combined heat and power system based on 18 kW Solid Oxide Fuel Cell (SOFC) using methane as fuel is presented. An ejector design, which reflects the real system conditions in the view of the flow characteristics, is provided and the ejector performance is numerically investigated for various methane pressure to exhaust pressure ratios and methane inlet temperatures. The results show that the fuel inlet temperature and the pressure ratio of the methane to exhaust significantly affect the steam to carbon ratio (STCR) and entrainment ratio. The higher pressure ratio and methane temperature allow a high entrainment ratio and STCR, but as pressure ratio and methane temperature increase, STCR and entrainment ratio remain unchanged after a specific value. 1140 different scenarios related with the inlet and outlet pressures of the ejector and methane temperature are created to determine the optimum operating conditions. The simulations show that the optimum methane inlet pressure is 7 bar and exhaust pressure is 1.159 bar for the ejector geometry of the interest. The entrainment ratio and STCR are determined as 2.05 and 0.92, respectively at this optimum scenario.
AtıfScopus34WoS31OpenAlex37İncele - MakaleAçık Erişim2017Scopus SJRQ3A fourth order approximation of the neumann type overdetermined elliptic problem
Ashyralyyev, Charyyar
In this paper, we consider an inverse elliptic problem with Neumann type overdetermination and construct a fourth order of accuracy difference scheme for its solution. Stability, almost coercive stability and coercive stability estimates for the solution of difference problem are proved. Later, we construct a fourth order difference scheme for an inverse problem for multidimensional elliptic equation with Neumann type overdetermination and Dirichlet boundary condition. Finally, we illustrate numerical example with descriptions of numeric realization in a two-dimensional case.
AtıfScopus19WoS12OpenAlex17İncele - BildiriAçık Erişim2017THE EFFICIENCY of RANDOM FOREST METHOD for SHORELINE EXTRACTION from LANDSAT-8 and GOKTURK-2 IMAGERIES
Bayram, B.; Erdem, F.; Akpinar, B.; Ince, A.K.; Bozkurt, S.; Catal Reis, H.; Seker, D.Z.; Karas, I.R.; Rahman, A.A.; Isikdag, U.
Coastal monitoring plays a vital role in environmental planning and hazard management related issues. Since shorelines are fundamental data for environment management, disaster management, coastal erosion studies, modelling of sediment transport and coastal morphodynamics, various techniques have been developed to extract shorelines. Random Forest is one of these techniques which is used in this study for shoreline extraction.. This algorithm is a machine learning method based on decision trees. Decision trees analyse classes of training data creates rules for classification. In this study, Terkos region has been chosen for the proposed method within the scope of "TUBITAK Project (Project No: 115Y718) titled "Integration of Unmanned Aerial Vehicles for Sustainable Coastal Zone Monitoring Model – Three-Dimensional Automatic Coastline Extraction and Analysis: Istanbul-Terkos Example". Random Forest algorithm has been implemented to extract the shoreline of the Black Sea where near the lake from LANDSAT-8 and GOKTURK-2 satellite imageries taken in 2015. The MATLAB environment was used for classification. To obtain land and water-body classes, the Random Forest method has been applied to NIR bands of LANDSAT-8 (5th band) and GOKTURK-2 (4th band) imageries. Each image has been digitized manually and shorelines obtained for accuracy assessment. According to accuracy assessment results, Random Forest method is efficient for both medium and high resolution images for shoreline extraction studies.
AtıfScopus23WoS18İncele - BildiriYalnız künye2017Determination of the genesis of tertiary aged volcanic rocks in the gümüşhane (Ne Türkiye) with gamma ray spectrometer method
Maden, N.; Akaryali, E.; Aydınçakır, E.
Eastern Pontide orogenic belt located in the Alp-Himalayan fold belt is divided into three subzones such as northern, southern and axial zones. These zones are controlled by the NE, NW and E-W directed fault systems. The study area whose geodynamic evolution is still debated is situated in the southern zone of the Eastern Pontide Orogenic belt. The views proposed for the geodynamic evolution of the eastern Pontides can be grouped into three. The geodynamic evolution of the region and genesis of the volcanic rocks are evaluated with a total 305 gamma ray spectrometer measurements surveyed at the Tertiary aged rocks in the Gümüşhane area. Total abundances of thorium ranges from 0.12ppm to 2.97 ppm, from 0.27ppm to 2.32 ppm for uranium, and from 0.09 % to 8.72 % for potassium. The average contents of radioelement concentrations computed over all measurements is: 0.85 (±0.33sd), 1.2(±0.54sd) ppm and 0.57 (±0.63sd) %, for U, Th and K, respectively. Numerical results verify that the parental magma of the Tertiary aged volcanic rocks probably derived from an enriched mantle originated from upper continental crust, previously metasomatized by subducted derived fluids..
- MakaleAçık Erişim2017Scopus SJRQ1Antiproliferative and apoptotic effect of Morus nigra extract on human prostate cancer cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Burnaz, Nesibe Arslan; Yaman, Serap Ozer; Akbulut, Kubra; Mentese, Ahmet; Aliyazicioglu, Yuksel; Deger, Orhan
Background: Morus nigra L. belongs to the family Moraceae and is frequently used in traditional medicine. Numerous studies have investigated the antiproliferative effects of various extracts of different Morus species, but studies involving the in vitro cytotoxic effect of M. nigra extract are very limited. The purpose of this study was to evaluate the phenolic composition and antioxidant activity of dimethyl sulfoxide extract of M. nigra (DEM) and to investigate, for the first time, the probable cytotoxic effect in human prostate adenocarcinoma (PC-3) cells together with the mechanism involved. Methods: Total polyphenolic contents (TPC), ferric reducing antioxidant power (FRAP) and phenolic compounds of DEM were evaluated using spectrophotometric procedures and HPLC. The cytotoxic effect of DEM on PC-3 cells was revealed using the MTT assay. Mechanisms involved in the cytotoxic effect of DEM on PC-3 cells were then investigated in terms of apoptosis, mitochondrial membrane potential and cell cycle using flow cytometry, while caspase activity was investigated using luminometric analysis. Results: TPC and FRAP values were 20.7 ± 0.3 mg gallic acid equivalents and 48.8 ± 1.6 mg trolox equivalents per g sample, respectively. Ascorbic acid and chlorogenic acid were the major phenolic compounds detected at HPLC analysis. DEM arrested the cell cycle of PC-3 cells at the G1 phase, induced apoptosis via increased caspase activity and reduced mitochondrial membrane potential. Conclusions: Our results indicate that M. nigra may be a novel candidate for the development of new natural product based therapeutic agents against prostate cancer.
AtıfScopus71WoS66OpenAlex78İncele - MakaleAçık Erişim2017Scopus SJRQ2Excited Neutrino Search Potential of the FCC-Based Electron-Hadron Colliders
Caliskan, A.
The production potential of the excited neutrinos at the FCC-based electron-hadron colliders, namely, the ERL60⊗FCC with √s = 3.46 TeV, the ILC⊗FCC with √s = 10 TeV, and the PWFA-LC⊗FCC with √s = 31.6 TeV, has been analyzed. The branching ratios of the excited neutrinos have been calculated for the different decay channels and shown that the dominant channel is ∗→eW+. We have calculated the production cross sections with the process of ep→∗q→eW+q and the decay widths of the excited neutrinos with the process of ∗→eW+. The signals and corresponding backgrounds are studied in detail to obtain accessible mass limits. It is shown that the discovery limits obtained on the mass of the excited neutrino are 2452 GeV for Lint=100 fb-1, 5635 GeV for Lint=10 fb-1 (6460 GeV for Lint=100 fb-1), and 10200 GeV for Lint=1 fb-1 (13960 GeV for Lint=10 fb-1), for the center-of-mass energies of 3.46, 10, and 31.6 TeV, respectively.
AtıfScopus10WoS10OpenAlex13İncele - MakaleAçık Erişim2017Scopus SJRQ2Phenolic characterisation and antioxidant activity of Primula vulgaris and its antigenotoxic effect on fibroblast cells
Ozkan, Mehtap Tugce; Aliyazicioglu, Rezzan; Demir, Selim; Misir, Sema; Turan, Ibrahim; Yildirmis, Sermet; Aliyazicioglu, Yuksel
Background: Primula vulgaris has been used in traditional treatment, and its biological functions are attributed to its polyphenolics content. Objectives: The aim of this study was to determine the phenolics composition and the antioxidant activity of water extract of P. vulgaris (WEP) and to determine its probable preventive effects against H2O2-induced DNA damage in human fibroblast cells. Methods: The total polyphenolic content (TPC), ferric reducing antioxidant power (FRAP), and radical scavenging activity of WEP were determined using spectrophotometric methods. Phenolic compounds and antigenotoxic effects of WEP were evaluated using HPLC and comet assay, respectively. Results: The TPC and FRAP values of WEP were 15.023 ± 0.84 mg gallic acid and 82.63 ± 0.31 μM trolox per g sample, respectively. ρ-coumaric acid and rutin were detected as major phenolics. Moreover, WEP reducedH2O2-induced DNA damage in a concentration dependent manner in fibroblast cells compared to the positive controls (only 20 μMH2O2 treatment). Conclusions: Primula vulgaris can be used in food, cosmetics, and drug industries because of its antioxidant and antigenotoxic activities.
AtıfScopus26WoS30OpenAlex25İncele - MakaleYalnız künye2017Scopus SJRQ3The effect of plasma electrolytic oxidation process parameters on the tribocorrosion properties of TiO2 coatings
Sukuroglu, Ebru Emine; Farzi, Hamed; Sukuroglu, Suleyman; Totik, Yasar; Arslan, Ersin; Efeoglu, Ihsan
Despite the fact that Titanium and its alloys are materials which have excellent corrosion-resistant properties, they have poor wear and friction performance under tribological conditions. The aim of this study is to find suitable parameters for the surface treatment of Cp-Ti substrates which are used under saline environment. In this study, TiO2 coatings were grown on Cp-Ti substrates at different frequencies which are parameters of the coating process. Due to its low cost and ability to achieve high thicknesses, The Plasma Electrolytic Oxidation (PEO) method was applied to grow TiO2 coatings. The microstructures, morphology, and crystallographic structure were analyzed using SEM and XRD. Tribocorrosion properties of the coatings were investigated using a combination of the pin-on-disk wear test and potentiodynamic polarization test units. The frequency is known to have a strong impact on the PEO process. The impacts of frequency changes on the PEO coating performance were examined under a constant voltage. As result, the increase of the frequency caused smaller pores and cracks in the surface morphology of the coating and at the same time this yielded an increment on the tribocorrosion behavior of the coating.
AtıfScopus20WoS18OpenAlex18İncele - MakaleYalnız künye2017Scopus SJRQ2The operator method for local fractional linear differential equations
Ünal, Emrah; Gökdoğan, Ahmet; Cumhur, İshak
In this work, we give the particular solution for nonhomogeneous sequential linear conformable fractional differential equations with constant coefficients by using the operator method.
AtıfScopus9WoS7OpenAlex9İncele - MakaleAçık Erişim2017Scopus SJRQ2Comparison of stochastic and random models for bacterial resistance
Merdan, Mehmet; Bekiryazici, Zafer; Kesemen, Tulay; Khaniyev, Tahir
In this study, a mathematical model of bacterial resistance considering the immune system response and antibiotic therapy is examined under random conditions. A random model consisting of random differential equations is obtained by using the existing deterministic model. Similarly, stochastic effect terms are added to the deterministic model to form a stochastic model consisting of stochastic differential equations. The results from the random and stochastic models are also compared with the results of the deterministic model to investigate the behavior of the model components under random conditions.
AtıfScopus25WoS25OpenAlex25İncele