Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2024Scopus SJRQ2
    Shape variation in cranium, mandible and teeth in selected mouse strains

    Ağaç, Duygu Küçük; Oktay, Ece; Onuk, Burcu; Kabak, Murat; Gündemir, Ozan

    There are different strains of laboratory mouse used in many different fields. These strains differ anatomically. In order to determine these anatomical differences, shape analysis was conducted according to species. CD-1, C57bl/6 and Balb-c strains were preferred to study these differences. Forty-eight adult mouse strains belonging to these strains were utilized. The bones were photographed and geometric morphometry was applied to these photographs. Principal Component Analysis was applied to determine shape variations. In Principal component 1 for cranium, CD-1 and C57bl/6 strain groups showed different shape variations, while Balb-c strain group showed similar shape variations to the other strain groups. Principal Component 1 for the mandible separated the CD-1 and C57bl/6 strain groups in terms of shape variation. Principal Component 2 explained most of the variation between the C57bl/6 and CD-1 lineage groups. In PC1 for molars, the CD-1 group showed a different shape variation from the other groups. Mahalanobis distances and Procrustes distances were measured using Canonical variance analysis to explain the differences between the lineage groups. These measurements were statistically significant. For cranium, in canonical variate 1, CD-1 group of mouse and Balb-c group of mouse were separated from each other. In canonical variate 2, C57bl/6 group of mouse were separated from the other groups. For mandible, Balb-c group of mouse in canonical variate 1 and CD-1 group of mouse in canonical variate 2 were separated from the other groups. For molars, CD-1 group of mouse in canonical variate 1 and Balb-c group of mouse in canonical variate 2 were separated from the other groups. It was thought that these anatomical differences could be caused by genotypic factors as well as dietary differences and many different habits that would affect the way their muscles work.

  • MakaleAçık Erişim2024Scopus SJRQ1
    Chemical Content by LC–MS/MS, Antiglaucoma, and Antioxidant Activity of Propolis Samples From Different Regions of Türkiye

    İzol, Ebubekir; Bursal, Ercan; Yapıcı, İsmail; Abdullah Yilmaz, Mustafa; Yilmaz, İsa; Gülçin, İlhami

    Propolis is a sticky substance produced by bees because of the reaction of beeswax, pollen, and bee enzymes. Particularly, their biological activity and chemical content attract attention. Thus, in this study, the total amount of phenolic and flavonoid substances, Fe3+-Fe2+, Cu2+ (cupric ions reducing activity [CUPRAC]), and Fe3+-TPTZ (ferric ions reducing antioxidant power [FRAP]) reducing, and DPPH• and ABTS•+ scavenging assays in vitro antioxidant properties of propolis samples obtained from four different provinces of Türkiye were determined. In addition, the chemical content of propolis samples was quantitatively determined by LC–MS/MS, and the antiglaucoma property was revealed by hCAII enzyme inhibition. Propolis samples from Ordu presented the highest amounts of total phenolic and flavonoid content (492.3 ± 5.8 and 96.1 ± 2.1, respectively) and also highest antioxidant activity (DPPH• and ABTS•+ IC50 [μg/mL]: 8.884 ± 0.84 and 4.589 ± 0.80, respectively; Fe+3, CUPRAC, and FRAP: 1.051 ± 0.012, 1.021 ± 0.008, and 0.957 ± 0.007 μg/mL, respectively). hCAII enzyme inhibition was highest in Muş propolis (IC50 [μg/mL]: 8.6) as determined. By LC–MS/MS, 53 different components were screened and 35 bioactive components were determined. According to the results, propolis was found to be a raw material because it contains high concentrations of acacetin, chrysin, caffeic acid, and quinic acid (123.824, 24.759, 47.779, and 16.32 mg analyte/g extract, respectively).

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2024Scopus SJRQ3
    The effect of transurethral resection of the prostate on sexual life quality in patient spouses

    Aydin Sayilan, Aylin; Kulakac, Nursen

    The purpose of this study was to determine the effect of transurethral resection of the prostate (TURP) surgery on quality of sexual life in patients' spouses. A pre/post-operative test, quasi-experimental design with no control group was employed. The research was conducted in the urology clinics of two hospitals in the west of Turkey between 30 June and 30 September 2022. It was completed with 172 patient spouses recruited using non-probability sampling. The study data were collected using an individual information form and the Sexual Quality of Life-Female questionnaire. The preoperative test applied prior to surgery was administered by the face-to-face interview method, while the postoperative test was completed by telephone interviews 8 weeks after the initial data collection. The mean age of the individuals undergoing TURP surgery in this study was 62.69 ± 7.98 years (min 40, max 77), and the mean age of the spouses was 57.91 ± 7.46 (min 39, max 73). Sexual Quality of Life-Female scores after surgery were significantly higher than the pre-surgical values (p < 0.001). A significant difference in sex life quality was determined in terms of age, education, employment status, presence of chronic disease, number of children, and ‘love marriages’ (p < 0.05). The sexual life quality of the spouses of patients exposed to TURP surgery increased significantly 8 weeks after the procedure. The quality of sex life was higher among individuals with higher education levels, working individuals, and those who ‘married for love’, but decreased in line with age and number of children.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2024Scopus SJRQ2
    A new method of smoothness-constrained magnetotelluric modelling with the utility of Pareto-optimal multi-objective particle swarm optimization

    Büyük, Ersin

    Particle swarm optimization, one of the modern global optimization methods, is attracting widespread interest because it overcomes the difficulties of conventional inversion techniques, such as trapping at a local minimum and/or initial model dependence. The main characteristic of particle swarm optimization is the large search space of parameters, which in a sense allows the exploration of the entire objective function space if the input parameters are properly chosen. However, in the case of a high-dimensional model space, the numerical instability of the solution may increase and lead to unrealistic models and misinterpretations due to the sampling problem of particle swarm optimization. Therefore, smoothness-constrained regularization techniques used for the objective function or model reduction techniques are required to stabilize the solution. However, weighting and combining objective function terms is partly a subjective process, as the regularization parameter is generally chosen based on some kind of criteria of how the smoothing constraints affect the data misfits. This means that it cannot be completely predefined but needs to be adjusted during the inversion process, which begins with the response of an initial model. In this paper, a new modelling approach is proposed to obtain a smoothness-constrained model from magnetotelluric data utilizing multi-objective particle swarm optimization based on the Pareto optimality approach without using a regularization parameter and combining several objective function terms. The presented approach was verified on synthetic models and an application with field data set from the Çanakkale–Tuzla geothermal field in Turkey. Findings from these analyses confirm the usefulness of the method as a new approach for all constrained inversions of geophysical data without the need to combine the objective function terms weighted by a regularization parameter.

  • MakaleAçık Erişim2024Scopus SJRQ3
    Influence of nickel addition on the microstructure, mechanical, and wear properties of Zn-40Al-2Cu alloy; [Einfluss des Nickelzusatzes auf das Gefüge, die mechanischen und die Verschleißeigenschaften der Legierung Zn-40Al-2Cu]

    Savaşkan, T.; Azaklı, Z.; Tan, H.O.

    To study the influence of nickel addition on the microstructure, mechanical and lubricated wear properties of Zn-40Al-2Cu alloy, one ternary and five quaternary Zn-40Al-2Cu-(0.5-2.5)Ni alloys were made by permanent mold casting. The wear behavior of these alloys was studied using a block-on-cylinder type test machine, after examining their microstructural and mechanical features. The microstructure of Zn-40Al-2Cu alloy was comprised of aluminum-rich α dendrites and a eutectoid α+η phase mixture. The addition of nickel caused the formation of intermetallic Al3Ni particles in the microstructure of this alloy. As the nickel content of alloys increased their hardness, friction coefficient, working temperature, and average surface roughness increased to certain extents but their strength, ductility, impact resistance, and wear volume decreased. However, the values of their wear volume and average surface roughness exhibited opposite changes with increasing nickel content. The worn surfaces of Zn-40Al-2Cu-Ni alloys were observed to be characterized by smearing and scratching marks. Furthermore, the wear and mechanical properties of these alloys were correlated, and the results were discussed in terms of their microstructural features. Finally, it may be concluded that the nickel addition adversely affects the ductility of Zn-40Al-2Cu alloy but increases its wear resistance.

  • MakaleYalnız künye2024Scopus SJRQ2
    Sulfonamide derivatives with benzothiazole scaffold: Synthesis and carbonic anhydrase I–II inhibition properties

    Öztürk, Cansu; Kalay, Erbay; Gerni, Serpil; Balci, Neslihan; Tokali, Feyzi Sinan; Aslan, Osman Nuri; Polat, Emrah

    The secondary sulfonamide derivatives containing benzothiazole scaffold (1–10) were synthesized to determine their inhibition properties on two physiologically essential human carbonic anhydrases isoforms (hCAs, EC, 4.2.1.1), hCA I, and hCA II. The inhibitory effects of the compounds on hCA I and hCA II isoenzymes were investigated by comparing their IC50 and Ki values. The Ki values of compounds (1–10) against hCA I and hCA II are in the range of 0.052 ± 0.022–0.971 ± 0.280 and 0.025 ± 0.010–0.682 ± 0.335, respectively. Some of these inhibited the enzyme more effectively than the standard drug, acetazolamide. In particular, compounds 5 and 4 were found to be most effective on hCA I and hCA II.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2024Scopus SJRQ2
    Optimizing Advanced High-Strength Steel Joints via Regional Rapid Cooling in Resistance Spot Welding

    Hıdıroglu, Mehtap; Aydın, Kemal; Kahraman, Nizamettin

    During resistance spot welding (RSW), the thermal cycles that occur cause microstructural differentiations in the heat-affected zones of martensitic steels, leading to internal stresses. In this context, a new and innovative methodology has been developed to minimize the adverse effects of heterogeneous hardness changes in the welding area on joint durability. This methodology utilizes a unique prototype setup based on the regional rapid cooling (RRC) process, which is integrated into the welding machine and operates in synchronization with the machine during the process. Through this setup, the aim is to effectively control the microstructure and hardness values in the welding area. This innovative approach presents potential improvements in the field of welding technology by aiming to optimize material performance during the welding process. According to microstructure results, the RRC process has narrowed the heat-affected zone to 1.27 mm, increased the hardness values by 9.2%, showed a 3% increase in tensile-shear strength, a 9% increase in cross-tension strength, and based on fatigue strength results, no fractures occurred in all specimens subjected to a force of 0.3 kN.

  • MakaleAçık Erişim2024Scopus SJRQ1
    Evaluation of microbiological, antioxidant, thermal, rheological and sensory properties of ice cream fermented with kefir culture and flavored with mint (Menthaspicata L.)

    Öztürk-Yalçın, Feyza; Ürkek, Bayram; Şengül, Mustafa

    Kefir is a healthy fermented dairy product, while ice cream is one of the most consumed dairy products. In this research, ice cream was fermented using a commercial kefir culture and flavored with a mint aroma in different proportions: 0% (KI), 0.2% (KIM2), 0.4% (KIM4), and 0.6% (KIM6). The study investigated the microbiological, thermal, rheological, textural, compositional, and sensory properties as well as antioxidant activity of kefir ice cream samples during 45-day storage. The lactic bacilli, lactic cocci, and Leuconostoc counts of samples were >7 log CFU/g, while the yeast counts were <4 log CFU/g. The microbiological properties (except for yeast counts) of the samples were coherent with legal limits. Antioxidant values (except for samples KIM2 and KIM6) values did not indicate significant differences (p <.05). The pH and melting rate values of the samples decreased with the addition of mint flavor, while acidity values increased. The addition of mint aroma caused significant changes in the thermal properties of ice cream. The overrun, a*, WI, and hardness values of the samples decreased based on the mint flavor concentration, whereas the viscosity and rheological increased. Samples KI and KIM2 were scored higher than other samples for all sensory properties. As a result, fermented ice cream flavored (0.2% mint) with mint could be produced as a desirable dairy product with potential functional properties.

    • SDG 2 · Açlığa Son
  • Derleme MakaleAçık Erişim2024Scopus SJRQ2
    Effect of eHealth Interventions on Symptom Management in CABG Surgical Patients: A Systematic Review

    Aydin, Aydanur; Celik, Sevilay Senol

    This study aimed to evaluate the effectiveness of eHealth interventions on symptom management outcomes of patients undergoing CABG surgery. A systematic review was performed on CINAHL, PubMed, Web of Science, Ovid MEDLINE, and Scopus from 2006 to June 2022. The Joanna Briggs Institute's evaluation tools for RCT and quasi-experimental studies were used to assess the methodological quality of the publications included in this review and to determine the extent to which each publication addressed the possibility of bias in its design. The raters' agreement was determined by using Cohen's kappa test, which yielded a kappa coefficient of 0.51. (PROSPERO registration number: CRD42023398498). A systematic analysis of 11 publications involving 2.586 patients showed that the eHealth intervention effectively increased activity and self-management. eHealth interventions, which are also effective in the management of psychological problems, had results that were partially effective in pain management and effective in quality of life. Digital healthcare has become an important component of patient care. Nurses providing care should be aware that eHealth interventions are showing promising results in patient care.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023Scopus SJRQ3
    Schiff Base Synthesis with a New Reliable Method and Investigation of Their Inhibition Effects on Glutathione S-Transferase and Cholinesterase Enzymes

    Balcı, Neslihan; Çelik, Hülya; Türkan, Fikret; Çelebioğlu, Neslihan; Çelik, Tuba; Bursal, Ercan

    The principle purpose of this study is to synthesize some Schiff base derivatives with a new microwave irradiation technique and investigate their enzyme inhibition effects. Related Schiff base compounds (1 a–1 h) were synthesized from 4-fluoro aniline and some substituted benzaldehyde derivatives (3 a–3 h). The chemical structures of Schiff bases were elucidated by various spectroscopic methods (1H NMR, 13C NMR). The inhibitory effects of the synthesized compounds against acetylcholinesterase, butyrylcholinesterase and glutathione S-transferase were investigated. The in vitro enzyme study determined the best enzyme inhibitors for AChE, BChE, and GST enzymes as 3 h, 3 b, and 3 e compounds, respectively. The results were compared with the standard drugs tacrine for cholinesterase and ethacrynic acid for GST enzymes. Molecular docking results demonstrated the low binding energy values between −5.8 kcal/mol and −8.7 kcal/mol with hydrogen bonding, hydrophilic, and hydrophobic interactions at the active catalytic sites of the enzymes.

  • MakaleAçık Erişim2023Scopus SJRQ2
    Sustainable water consumption and water-saving behaviours: A review of consumers' environmental and economic concerns in Turkey

    Avci, İbrahim

    Water, which plays an important role in human life, has been depleted as a result of changing consumption patterns, climate change and increasing population, and water scarcity has emerged as one of the most pressing issues facing the world in the coming years. One solution to this problem is to make more efficient and sustainable use of existing water resources. In this context, the study aims to investigate the effects of consumers' environmental and economic concerns on sustainable water consumption behaviour, as well as the mediating role of water-saving behaviour in these effects. For this purpose, it was discovered that environmental and economic concerns have positive effects on sustainable water consumption behaviour as a result of an analysis of data collected from 591 consumers in Turkey via the online survey method; it was determined that environmental concerns have no effect on water-saving behaviour, whereas economic concerns have a positive effect on water-saving behaviour. According to the findings of the mediation analysis, water-saving behaviour only serves to mediate the effect of economic concerns on sustainable water consumption behaviour.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
  • MakaleYalnız künye2023Scopus SJRQ3
    Determination of the Antioxidant Capacity of Puerarin and Its Effect on Cholinesterases by in vitro and in silico Methods

    İnan Ergün, Aslı; Topal, Meryem

    Puerarin, which was used as a natural isoflavone in this study, was obtained from the Kudzu plant. The inhibitory effect of puerarin on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes was investigated. The IC50 values of AChE (177.73 nM) and BChE (315.07 nM) were determined. The binding mechanism of puerarin, which has a high inhibitory effect on the active site of the enzyme, was demonstrated by the molecular docking method. The antioxidant activity was evaluated for the same molecule. For this purpose, Fe3+-Fe2+ reducing capacity, ABTS radical scavenging activity, CUPRAC method, DPPH⋅ scavenging activity and DMPD radical scavenging method were used. The percentage (%) inhibition amount of puerarin molecule was calculated as 99.33 % for ABTS radical scavenging activity, which is the more preferred method for natural products. The absorbtion value of iron reduction of Puerarin was 0.122±0.010, and the value of copper reduction was 0.633±0.026. Our research efforts include uncovering the potent antioxidant potential of puerarin and, simultaneously, a comparative study of tacrine, primarily emphasizing its inhibitory effects against AChE and BChE enzymes. The puerarin is expected to be a guide for drug discovery against many problems, especially oxidative cell damage in Alzheimer's disease, mitochondrial dysfunction (MD), cancer, and cardiovascular diseases.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023Scopus SJRQ1
    Evaluation of moral sensitivity and moral courage in intensive care nurses in Turkey during the COVID-19 pandemic

    Goktas, Sonay; Aktug, Cemile; Gezginci, Elif

    Background: During the COVID-19 pandemic, intensive care nurses may experience ethical issues related to fear of transmission, limited resources, and increased workload. Nurses' moral sensitivity and courage may have a role in dealing with these problems. Aim: The purpose of this study was to assess intensive care nurses' moral sensitivity and moral courage during the COVID-19 pandemic. Design: Descriptive cross-sectional survey. Methods: A total of 362 nurses working in the intensive care units of pandemic hospitals in Turkey participated in the study between January and March 2021. Data were obtained using a personal information form, the Moral Sensitivity Questionnaire, and the Nurses' Moral Courage Scale. A link to the online data collection tools was sent to the management of participating institutions, who forwarded it to nurses. Reporting followed the CHERRIES guidelines. Results: In this study, the response rate of nurses was 89%. The nurses' total mean moral sensitivity score was 90.70 ± 28.89 and their mean moral courage score was 82.08 ± 13.51. A weak inverse correlation was found between the nurses' moral sensitivity and moral courage scores (r = −.176, p =.001). Total moral sensitivity score differed significantly according to years of Intensive care unit (ICU) experience (p =.007). Total moral courage scores increased significantly with education level (p =.012), years of nursing experience (p =.016), and willingness to work in the ICU (p <.001). Conclusion: The study suggests that nurses working in the intensive care unit during the pandemic had moderate moral sensitivity and high levels of moral courage. Nurses' sociodemographic characteristics and ICU work conditions may affect their moral sensitivity and moral courage. Relevance to Clinical Practice: The results of this study can help guide efforts to improve moral courage and sensitivity and address ethical issues among ICU nurses.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYayıncıda açık erişim2023Scopus SJRQ3
    Postoperative symptom management perceptions and coping experiences of individuals with prostate cancer

    Kazımoğlu, Hatem; Ulutaşdemir, Nilgün; Kulakaç, Nurşen; Uzun, Sevda

    Objective: This study aims to examine in depth the perceptions of postoperative symptom management and coping experiences of individuals with prostate cancer. Material-Method: The study was conducted with 15 individuals with prostate cancer using a phenomenological research design, which is a qualitative research design. Interviews were conducted via the WhatsApp application. Results: The data were analysed using Colaizzi's phenomenological method. In the data analysis, two categories, five main themes, and 15 sub-themes emerged. In the category of symptom management perception, there are themes of pain management processes, the use of complementary and alternative therapies and practices to cope with symptoms and improve quality of life. In the category of coping experiences, the themes of individual coping, interpersonal relations, and productivity were obtained. Conclusion: Our study suggests that individuals with prostate cancer have difficulty in symptom management in the postoperative coping process, but they managed them effectively with the support of their spouse, family, and health care professionals.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2023Scopus SJRQ2
    LC-HRMS Profiling and Phenolic Content, Cholinesterase, and Antioxidant Activities of Terminalia citrina

    Özler, Ebubekir; Topal, Fevzi; Topal, Meryem; Öztürk Sarıkaya, Sevim Beyza

    Terminalia citrina (T. citrina) belongs to the Combretaceae family and is included in the class of medicinal plants in tropical countries such as Bangladesh, Myanmar, and India. The antioxidant activities of lyophilized water (WTE) and alcohol extracts (ETE) of T. citrina fruits, their phenolic content by LC-HRMS, and their effects on cholinesterases (ChEs; AChE, acetylcholinesterase, and BChE, butyrylcholinesterase) were investigated. Especially ten different analytical methods were applied to determine the antioxidant capacity. Compared with similar studies for natural products in the literature, it was determined that both WTE and ETE exhibited strong antioxidant capacity. Syringe and ellagic acids were higher than other acids in ETE and WTE. IC50 values for ETE and WTE in DPPH radical and ABTS⋅+ scavenging activities were calculated as 1.69–1.68 μg mL−1 and 6.79–5.78 μg mL−1, respectively. The results of the biological investigations showed that ETE and WTE had an inhibition effect against ChEs, with IC50 values of 94.87 and 130.90 mg mL−1 for AChE and 262.55 and 279.70 mg mL−1 for BChE, respectively. These findings indicate that with the prominence of herbal treatments, T. citrina plant may guide the literature in treating Alzheimer's Disease, preventing oxidative damage, and mitochondrial dysfunction.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2023Scopus SJRQ2
    Endemic Mountain Tea (Sideritis dichotoma Huter): Antioxidant and Antibacterial Activities, Mineral Content by ICP-MS and Phytochemical Content by LCHR-MS

    Öztürk Sarıkaya, Sevim Beyza; Zehiroğlu, Cuma

    Endemic Sideritis dichotoma Huter, herbal tea, is used for colds, coughs and digestive ailments. Since at least 25 % of the active ingredients of pharmacological drugs are obtained from plants, it is important to investigate many plants, both traditionally used and whose potential hasnt yet been discovered, before they disappear. When the results compared to other Sideritis species, it has better antioxidant activity in DPPH⋅ scavenging activity, Fe3+ and Cu2+ reducing capacity methods and is also rich in minerals, necessary for human body, K, Mg, Ca, P, S. Zone values (10–19,5 mm) obtained on S. aureus, P. aeruginosa, E. coli, S.enteritidis, E. faecalis, P. putida and K. pnemoniae strains are an indication that the plant has antibacterial activity. 27 secondary metabolites were identified by LC-HRMS. Verbascoside, pharmacologically active compound known to have antitumor effect, cytotoxic selectivity and anticancer activity, is the most abundant phenolic in ethanol extract (49297.13 mg/kg).

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022Scopus SJRQ2
    Antioxidant capacity and rheological, textural properties of ice cream produced from camel's milk with blueberry

    Sayar, Esra; Şengül, Mustafa; Ürkek, Bayram

    Blueberry was added to ice cream samples produced from camel's milk at different concentrations. The physicochemical, rheological, and sensory properties, total phenolic content (TPC), and antioxidant capacity of samples were investigated. The acidity and hardness values of the samples increased, but total solids, fat, protein, pH, ash, overrun values, and complete meltdown time significantly decreased with increasing concentration of blueberry. The L* and b* values decreased, while a* and H° values increased due to the presence of natural colorants in blueberry. The viscosity and consistency coefficient values of ice cream samples decreased depending on the blueberry concentration, whereas TPC and antioxidant capacity increased. The addition of blueberry did not have any affirmative or negative effect on the sensory properties of samples except for appearance, color, and flavor scores. Consequently, blueberry could be added to the ice cream produced using camel's milk at less than a ratio of 10% to improve its nutritional properties. Novelty impact statement: Ice cream made from camel's milk with blueberry is a novel dairy product. It is a functional product due to its high antioxidant activity and total phenolic component. The addition of blueberry does not have a negative effect on the sensory properties of the ice cream. As a result, blueberry and camel's milk could be used in new ice cream formulations to produce a nutritional and functional product.

    • SDG 2 · Açlığa Son
  • MakaleAçık Erişim2022Scopus SJRQ2
    The effect of motivational interview conducted by nurses on quality of life: Meta-analysis

    Uzun, Sevda; Özmaya, Esma

    Purpose: The aim of the study is to examine the effect of the motivational interviewing method conducted by nurses on the quality of life of patients with chronic diseases. Design and Methods: The studies examined in this meta-analysis study were obtained by scanning the PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK thesis databases between January and May 2021 without any year limitation. After the elimination, 16 studies were included in the study. The data were synthesized with meta-analysis and narrative methods. The total sample size of the studies was 14,425. Findings: This meta-analysis demonstrated that the motivational interviewing method applied by nurses in individuals with chronic diseases changed their quality of life (SMD: 0.258, 95% confidence interval: 0.076–0.441; Z = 2.775, p = 0.006, I2 = 89.97%). The variance between studies was statistically significant (p < 0.05) for the moderator of the measurement tools, the duration of the motivational interviews, and the country/continent of the studies were conducted (p < 0.05), suggesting that the measurement tools, the duration of the motivational interview, and the country/continent of the studies changed the effect size of the motivational interview method on the quality of life. Practice Implications: It has been concluded that the motivational interview method applied by nurses who are in a critical position in the protection and development of health improves the quality of life of individuals with chronic diseases.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022Scopus SJRQ2
    Comparison of the relationship between menopausal symptoms and loneliness and anger

    Ozcan, Handan; Savci, Hamit; Canik, Muhammed; Ayan, Mahsun; Bas, Cağla Firdevs

    Purpose: This study aimed to determine the relationship between the symptoms of anger and loneliness among women in the menopausal period. Design and Methods: A total of 200 women in the menopausal period were interviewed within the scope of this study. Descriptive Information Form, UCLA Loneliness Scale, Trait Anger and Anger Expression Scale and Menopause-Specific Quality of Life Questionnaire were used to collect data. Findings: The mean score of the UCLA Loneliness Scale was found as 53.61 ± 7.68 and it was observed that the participants had high traits of anger and a high-level of loneliness. Loneliness and anger increase when menopausal symptoms increase in women. Practice Implications: Menopause is generally perceived by women as a troublesome period instead of being a normal life process. In order for women to spend this period at a more comfortable and desirable level, it is important to know cultural characteristics, social support systems, coping mechanisms.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022Scopus SJRQ2
    Flaxseed and Cornelian cherry: Development of a functional cookie using response surface methodology

    İlyasoğlu, Huri; Arslan Burnaz, Nesibe; Arpa Zemzemoğlu, Tuba Eda

    Consumers' demand for healthy foods has been increased. The aim of this study was to develop a functional cookie from wheat flour with flaxseed (FS) and Cornelian cherry (CC). The effects of the levels of FS flour (10–30 g for 100 g composite flour) and CC powder (2–10 g for 100 g composite flour) in the cookie formulation on the cookie properties were investigated by using response surface methodology. The lightness of the cookies was decreased with the addition of the FS and CC. The incorporation of the FS into the formulation enhanced the content of omega-3 fatty acids. Both FS and CC enhanced the total phenolic contents (TPCs) and antioxidant capacity of the cookies. Moreover, they did not have effects on the hardness and overall acceptability. The developed cookie contained FS (23.6 g 100 g−1) and CC (10 g 100 g−1) that provided α-linolenic acid (16.5 g 100 g−1), TPC (340.2 mg GAE 100 g−1), and antioxidant capacity (996.6 μmol TEAC 100 g−1). Our study indicated that the combination of wheat flour with FS with CC can have the potential to enhance the nutritional and functional values of the cookies. Novelty impact statement: The combination of wheat flour with flaxseed and Cornelian cherry in the cookie formulation enhanced the contents of omega-3 fatty acids, total phenolic content, and antioxidant capacity of the cookies. The developed cookie may be an alternative product for consumers who look for healthy bakery products.

    • SDG 2 · Açlığa Son