Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(15)
- Tuncer, Metin(8)
- Kulakaç, Nurşen(7)
- Topal, Meryem(5)
- Emirza, Elif Güzide(4)
- Topal, Fevzi(4)
- Tuncer, Gülsüm Zekiye(4)
- Balci, Neslihan(3)
- Yapıcı, İsmail(3)
- Öztürk Sarıkaya, Sevim Beyza(3)
- Ürkek, Bayram(3)
- Akdoğan, Arda(2)
- Akmeşe, Osman(2)
- Aktepe Coşar, Dilan(2)
- Aliyazicioglu, Yüksel(2)
- Altay, Ahmet(2)
- Arslan Burnaz, Nesibe(2)
- Aslan, Osman Nuri(2)
- Aydin Sayilan, Aylin(2)
- Aydın, Kemal(2)
- Balcı, Neslihan(2)
- Baltacı, Cemalettin(2)
- Bayrak, Nurten Gülsüm(2)
- Bursal, Ercan(2)
- Büyük, Ersin(2)
- Demir Çam, Sevgi(2)
- Demir, Selim(2)
- Demirağ, Hatice(2)
- Ediz, Çiçek(2)
- Gulcin, Ilhami(2)
- Gültekin, Ergün(2)
- Gülçin, İlhami(2)
- Kalay, Erbay(2)
- Khorshtd, Leyla(2)
- Köksal, Ekrem(2)
- Sünnetçi, Kadir(2)
- Turan, İbrahim(2)
- Turan, Şeyma(2)
- Ulutaşdemir, Nilgün(2)
- Zehiroğlu, Cuma(2)
Yayınlar
- MakaleAçık Erişim2026Detrital zircon ages, Lu-Hf isotopes of zircon grains, Sr-Nd isotopes on whole rock and geochemistry of Campanian turbidites in the Eastern Pontides (NE Türkiye): A provenance assessment and Gondwana records
Eker, Çiğdem Saydam; Yücel, Cem; Kaygusuz, Abdullah; Aydınçakır, Emre; Jeong, Youn-Joong; Yılmazer, Sinan; Sünnetçi, Kadir
Detrital zircons are crucial stand-ins for the history of continental crust growth and disintegration, as well as the dispersal and assembly of supercontinents. Detrital zircons are effectively used to assess crustal history because sediments transport zircons from source rocks that are no longer at the surface. This study presents detailed Lu-Hf isotopic, U-Pb geochronological analyses of zircon, Sr-Nd isotopic analyses and whole-rock geochemical results from sandstone, volcanically derived sandstone and tuff samples of the Campanian-aged Bozbent Member in the Eastern Pontide Orogen belt of the Sakarya Zone. Sedimentological analyses show that the Bozbent Member was transported and deposited by turbidite currents, while petrographic and geochemical analyses show that the sandstones range from greywacke to litharenite. In this study, U-Pb ages of detrital zircon obtained from Campanian sandstones are presented, along with in situ εHf data. A magmatic origin is indicated by the majority of zircons' oscillatory zoning and by Th/U ratios ranging from 0.2 to 1.5. The ages of detrital zircons range from 2819 to 78 Ma, with most of these zircons being Proterozoic (552–994 Ma). Proterozoic zircons are detrital zircons associated with the Gondwana and the African Craton. The whole-rock geochemical data and Sr-Nd isotope compositions of the sandstones are consistent with local Carboniferous felsic plutons, Jurassic mafic and felsic plutons, Jurassic volcanic rocks, Jurassic clastic rocks and clastic material from Precambrian recycled sediments. It was calculated that more than 90% of the detrital zircons had crystallisation ages older than their depositional ages (CA-DA > 150 Ma, indicative of an extensional basin model). These findings indicate that the Campanian-aged Bozbent Member turbiditic sequence in the Eastern Pontides was deposited in an extensional fore-arc basin and therefore exhibits the petrographic and geochemical characteristics of passive margin sandstones.
- MakaleAçık Erişim2025Superconducting Properties of Welded Three Top-Seeded YBa2Cu3O7−x Produced with NdBCO/YBCO/MgO Thin-Film Seed
Batur, Kübra Nur; Duman, Şeyda; Çakir, Bakiye; Başoğlu, Mehmet; Aydiner, Alev
This study investigates hollow single-crystal top-seeded melt growth (TSMG) YBa2Cu3O7−x (YBCO or Y123) samples welded with Ag-added TSMG YBCO solder materials produced using NdBCO/YBCO/MgO thin-film seeds. Three main samples and one solder material are produced by the TSMG method. In order to increase the dimensions of the bulk YBCO superconductor, two slices of the solder material and the main samples are stacked on top of each other with the c-axis parallel and welded at 1030 °C. X-ray diffraction patterns, polarized optical photographs, and SEM micrographs are taken to determine the structural properties of the samples. A preferential orientation in the c-axis is observed with a good connection. Low-temperature resistance and magnetization measurements are made for the specimens taken from the welding region. A sharp superconducting transition occurs at 0 T around 93 K for welding regions of W-ab and W-bc specimens. The critical current densities (Jc) are high as in the main samples. At the same time, the Jc values at 77 K and 0 T are found as 1.54 × 104, 1.98 × 104, 2.21 × 104, 2.31 × 104, and 2.36 × 104A cm−2 for the W-a, W-ab, W-b, W-bc, and W-c specimens, respectively. The single-grain feature is not impaired; thus, the absence of additional grain boundaries facilitates the current passage.
- MakaleAçık Erişim2025The effect of using a local skin cooling device on arteriovenous fistula cannulation pain and comfort level of patients on hemodialysis: A single-blind randomized controlled study
Demırağ, Hatice; Kulakaç, Nurşen
Introduction: The study aimed to investigate the impact of the using local skin cooling on arteriovenous fistula cannulation pain and the comfort levels of hemodialysis patients. Methods: The single-blind randomized controlled trial was formed with 50 patients between June 20, 2023, and July 31, 2023, in the hemodialysis units of two state hospitals in Turkey. Patients were randomly assigned to either the experimental group (n = 25) or the control group (n = 25) using the block randomization method. This data were collected through the use of the CoolSense device, the “Patient Information Form,” the “Verbal Category Scale,” and the “General Comfort Scale.” Patients in the experimental group received the local skin cooling for five seconds during arteriovenous fistula cannulation, while the control group followed the standard hospital protocol. The study was registered on Clinical Trials (NCT06144801). Findings: The study revealed that the application of the local skin cooling during arteriovenous fistula cannulation significantly reduced pain and increased patients’ comfort levels, demonstrating an anesthetic effect (p < 0.001). Furthermore, it was observed that as pain levels decreased, patient comfort levels increased (p < 0.001). Discussion: It is concluded that the using lokal skin cooling is an effective tool for reducing pain and enhancing comfort during arteriovenous fistula cannulation in hemodialysis patients.
- MakaleAçık Erişim2025Effect of eHealth Interventions on Medication Adherence in Kidney Transplant Recipients: Meta-Analysis of Randomised Controlled Trials
Tuncer, Metin; Tuncer, Gülsüm Zekiye
Background: Kidney transplant recipients must take immunosuppressive drugs for life, and medication non-adherence is a primary risk factor for graft loss and death. With the advancement of technology, electronic health applications are widely used in chronic disease management and offer the potential to improve medication adherence in kidney transplant recipients. Aim: This meta-analysis aims to evaluate randomised controlled trials (RCTs) that assess the effectiveness of eHealth interventions in improving medication adherence among kidney transplant recipients. Methods: This study, which was designed as a systematic review and meta-analysis, followed PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) protocols in the planning and reporting phases. Electronic databases and manual literature searches were the two main data sources. Full-text RCTs in PubMed, Medline, Web of Science and Scopus databases were systematically searched. The searches covered studies from 2014 to March 2024. Results: The search yielded 524 articles. Eight RCTs with 779 participants were included in the analysis. The meta-analysis results indicated that, compared with the control group, adherence rates (RR: 1.19; 95% CI: 1.06–1.35; p = 0.01. Heterogeneity: Q = 8.69; p = 0.28; I2 = 19%) and adherence scores (SMD: 0.17; 95% CI: 0.05–0.29; p = 0.02. Heterogeneity: Q = 0.45; p = 0.93; I2 = 0%) significantly increased in the eHealth intervention group compared with the control group. Conclusion: The findings of this report show that eHealth interventions to improve medication adherence in kidney transplant recipients show favourable outcomes compared with standard care. We recommend eHealth interventions to improve long-term survival and patient outcomes in kidney transplant recipients.
- MakaleYalnız künye2025Beyond the Call to Serve: Measuring Donation Motives in Social Work Students
Akinci, Habibullah; Yücel, İbrahim; Kalayci, Erdinç
Understanding the motivations behind charitable giving is crucial, particularly among emerging social work professionals. This study presents the development and validation of a novel “Donation Motives Scale” specifically designed for social work students. Drawing upon established theories of donation behavior and existing measurement tools, a comprehensive item pool was generated. Through rigorous analysis, a 17-item scale emerged, structured around four distinct factors: social dignity and appreciation, social responsibility, personal satisfaction and self-evaluation, and humanity and empathy. The scale demonstrated strong validity and reliability within a sample of university students, indicating its potential as a robust tool for investigating donation motives within this population.
- MakaleAçık Erişim2025Geochemical evaluation of black limestones in the Early Cretaceous platform carbonates of Gümüşhane (NE Turkey): An insight into petroleum source rock potential and palaeoenvironment conditions
Saydam Eker, Çiğdem; Arı, Uğur Volkan; Alemdağ, Selçuk
This study assesses the organic matter (OM) content, kerogen type, maturity, depositional environment conditions and sedimentation model of Early Cretaceous (Berriasian–Aptian) black limestones in NE Turkey using geochemical analyses, including Rock-Eval/total organic carbon (TOC), gas chromatography–mass spectrometry, gas chromatography, major and trace elements and stable carbon isotope of OM measurements. The investigated black limestones' TOC, hydrogen index and potential yield values range from 0.07 to 2.91 wt%, 76 to 636 mg HC/g TOC and 0.15 to 11.17 mg HC/g rock, respectively. These results indicate that the examined limestones have variable source rock potential, ranging from low to high. Tmax values, calculated saturated biomarkers and aromatic components suggest that the OM contained in the black limestones varies between thermally immature and mature, consistent with the potential index values. The OM found in the black limestone contained kerogen varying between type I and III. It is a composition of marine and terrigenous OM, as shown by the δ13C isotope values, biomarker components and n-alkane distributions and their parameters. This OM was deposited in a salinity water environment with marine–terrigenous (transitional) surroundings under oxic, suboxic to anoxic and arid–hot climate conditions. These findings provide critical insights for assessing the hydrocarbon potential of carbonate platforms in similar geological settings.
- MakaleAçık Erişim2025The Correlation Between Circulating Fetuin-A Levels and Fetuin-A to Adiponectin Ratio With Obesity in a Turkish Population: A Case-Control Study
Icer, Mehmet Arif; Koçak, Tevfik; Ağagündüz, Duygu; Yıldıran, Hilal
The relationship between serum fetuin-A levels and obesity has not been fully understood. This study aims to elucidate the levels of serum fetuin-A and F/A ratio in obesity and contribute to the literature on whether they could be novel clinical predictors modulated through body composition and nutrition. The study included 73 participants who were obese and 71 participants with normal weight, aged between 18 and 65 years. Certain anthropometric measurements of the individuals were taken, and a body composition analysis was performed. In addition, 3-day food records (consecutive days: 2 weekdays and one weekend day) were taken. Serum levels of fetuin-A (ng/mL) and adiponectin (μg/mL) were measured using an enzyme-linked immunosorbent assay (ELISA) method. The F/A ratio was obtained by dividing fetuin-A (ng/mL) by adiponectin (μg/mL). Serum fetuin-A (ng/mL) level and F/A ratio are higher in obese participants than in normal weight (p < 0.05). Body weight (kg) (r = 0.553, p ≤ 0.001), body mass index (kg/m2) (r = 0.492, p ≤ 0.001), waist circumference (cm) (r = 0.522, p ≤ 0.001), body fat percentage (%) (r = 0.203, p = 0.015), serum fasting blood glucose levels (mg/dL) (r = 0.317, p ≤ 0.001), and dietary protein intake (kg) (r = 0.165, p = 0.048) were observed to be positively correlated with serum fetuin-A levels. Positive correlations were also observed between these parameters and the F/A ratio (p < 0.05). Negative correlations were found between serum adiponectin and these parameters (p < 0.05). In addition, when dietary cholesterol intake was kept constant, a 1-unit increase in dietary energy intake (kcal) resulted in a 0.043-fold increase in serum fetuin-A (p < 0.05). The study results support theories suggesting the involvement of serum fetuin-A levels and the F/A ratio in the pathogenesis of obesity. The higher serum fetuin-A levels and F/A ratio found in obese participants may be considered as new clinical determinants that could be regulated through body composition and nutrition.
- MakaleAçık Erişim2025Effectiveness of Psychosocial Interventions in Alcohol and Substance Use Disorders: A Meta-Analysis Study
Helvacı Çelik, Fatma Gül; Bayrak, Nurten Gülsüm; Uzun, Sevda
Alcohol and substance use disorders (ASUD), are increasing worldwide, and these psychiatric disorders are difficult to treat. The search for new treatments for these disorders continues. Psychosocial interventions (PI) are among them, and it is important to evaluate their effectiveness. This study aimed to assess the effectiveness of PI applied to individuals with ASUD. This meta-analysis was conducted by searching PubMed, Web of Science, EBSCOhost, Google Scholar, and YOK Thesis Center databases without year restrictions between October and December 2023. After reviewing the studies, 18 research articles were included in the analysis. The meta-analysis revealed that PI applied to individuals with ASUD were effective in reducing depression (SMD: −0.753, 95% CI: −1.215 to −2.91; I2 = 94.515; p < 0.05) and enhancing self-efficacy (SMD: 0.709, 95% CI: 0.096–1.321; I2 = 93.34; p < 0.05). However, these interventions were not found to be effective in improving self-esteem (SMD: 0.655, 95% CI: −1.641 to 0.331).
- MakaleAçık Erişim2025Comprehensive Analysis of the Antioxidant and Enzyme Inhibitory Properties and Phenolic Compounds of Phlomis armeniaca: Potential Applicant in Neurodegenerative Diseases
Menevseoglu, Ahmed; Yılmaz, Fırat; Topal, Meryem; Topal, Fevzi
This study investigates the antioxidant and enzyme inhibitory properties of Phlomis armeniaca, a perennial plant native to the eastern and southeastern regions of Turkey. Ethanol extracts of the plant were analyzed using various bioanalytical methods, including Fe3⁺-Fe2⁺ reducing power, Cupric Reducing Antioxidant Capacity, 1,1-diphenyl-2-picryl-hydrazyl (DPPH), and 2,2-azinobis 3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical scavenging activities, as well as total phenolic and flavonoid content assessments. The results showed that P. armeniaca is rich in phenolic (38.75 ± 0.59 µg gallic acid equivalents/mg extract) and flavonoid compounds (39.34 ± 4.08 µg quercetin equivalents/mg extract). The plant demonstrated significant inhibitory effects on acetylcholinesterase (half-maximal inhibitory concentration [IC50]: 45.00 ± 0.48 mg/mL) and butyrylcholinesterase (IC50: 84.51 ± 0.84 mg/mL) enzymes, indicating its potential use in treating neurodegenerative diseases such as Alzheimer's. The study also highlighted P. armeniaca’s high chlorogenic acid, salicylic acid, 4-dihydroxybenzoic acid, and quinic acid contents, supporting its antioxidant capacity. These findings suggest that P. armeniaca could be a valuable natural resource for developing therapeutic agents to manage oxidative stress and related conditions, warranting further pharmacological exploration.
- MakaleAçık Erişim2025Research of Peganum harmala: Phytochemical Content, Mineral Profile, Antioxidant, Antidiabetic, Anticholinergic Properties, and Molecular Docking
İzol, Ebubekir; Turhan, Münire; Yapıcı, İsmail; Necip, Adem; Abdullah Yılmaz, Mustafa; Zengin, Gökhan
Peganum harmala is a significant medicinal, aromatic plant used in traditional medicine and the subject of many studies. In this study, the phytochemical compound and mineral profile of the plant's ethanol extract were identified quantitatively. Antioxidant properties were determined by total phenolic and flavonoid content, FRAP, DPPH, CUPRAC, ABTS, metal chelating, and phosphomolybdenum assays. Antidiabetic, anticholinergic, and skin care properties were specified by the inhibition of tyrosinase, α-glucosidase, α-amylase, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzymes, respectively. In addition, binding interactions of major phytochemicals with all enzymes were investigated by molecular docking studies. The phytochemical compound of the extract contained significant bioactive components such as acacetin, gentisic acid, p-coumaric acid, quinic acid, rutin, apigenin, and chrysin, while the mineral profile was rich in salt elements. AChE, BChE, tyrosinase, α-amylase, and α-glycosidase enzyme inhibitor results were determined as 2.99 mg GALAE/g, 4.14 mg GALAE/g, 35.8 mg KAE/g, 2.76 mmol ACAE/g, and 1.20 mmol ACAE/g, respectively. As a result, it was identified that it had antioxidant properties and strongly inhibited all enzymes except tyrosinase. The docking scores of major bioactive phytochemicals were found to be high. The best binding pose was obtained by docking acacetin into the active site of AChE (PDB: 4EY7), BChE (PDB: 4BDS), α-glucosidase (PDB: 3WY1), α-amylase (PDB: 6GXV) and tyrosinase (PDB: 2Y9X) receptors. Docking score values were calculated as −10.4, −9.2, −8.8, −7.8, and −7.4 kcal/mol, respectively. Thus, it was revealed that P. harmala has an important potential in drug research and treatment of some diseases.
- MakaleAçık Erişim2025Microencapsulation of Caucasian blueberries (Vaccinium arctostaphylos L.) anthocyanins: Colour stability in varying storage conditions
Girgin, Serpil; Üçüncü, Osman; Baltacı, Cemalettin; Muslu Aykoç, Ayşe
The aim of this study was to investigate the extraction of anthocyanins from the fruits of Caucasian blueberry (Vaccinium arctostaphylos L.) and examine the colour stability of anthocyanins encapsulated through spray drying in model systems. The trials were conducted to determine the optimal conditions for anthocyanin extraction using an ultrasonic water bath at temperatures of 25, 50 and 75°C. The ideal anthocyanin extraction occurred at 25°C using 100% acetone in an ultrasonic bath for 15 min at 35 kHz. Anthocyanin concentrations were evaluated using the pH differential method. The extracted anthocyanins were encapsulated through spray drying with maltodextrin as the encapsulating material. The encapsulation efficiency was 80.4 ± 0.20%, and the anthocyanin retention rate was 83.0 ± 0.76%. The coloured capsules were added to model systems with pH values of 4.50, 5.00, 5.50 and 6.00. The colour values (L* 50.16 ± 0.05, a* 4.08 ± 0.04, b* −9.35 ± 0.01, H° 293.57 ± 0.15, C* 10.20 ± 0.03) were measured during varying storage conditions. The results showed, that colour loss began on the fifth day and this was accelerated with higher temperatures and pH values. It was found that encapsulation significantly preserved the stability of the blue colour and the loss of the blue colour followed first-order reaction kinetics. The study showed that the blue colour of microcapsules was best preserved at pH 5.00 at 25°C. In this case, the measured total colour change (∆E) was 5.86, the activation energy (Ea) was 37.64 kJ/mol, and the half-life (t1/2) was determined to be 19.08 days.
- MakaleAçık Erişim2025Investigation of the relationship between attitudes toward migration and life satisfaction of nurses working in Turkey
Tuncer, Metin; Tuncer, Gülsüm Zekiye; Turan, Şeyma; Khorshtd, Leyla
Background: Nurse migration contributes to the nursing shortage in developing countries. Understanding nurses' attitudes toward migration and related factors is crucial for policy-making and healthcare workforce planning in Turkey. Aim: This study aimed to investigate the relationship between nurses' attitudes toward migration and their life satisfaction in Turkey. Methods: The study included working nurses with social media accounts on a social media platform in Turkey who followed nursing-related content. A sample of 423 nurses completed an online survey. Independent variables included nurses' sociodemographic characteristics and inclination toward migration, while dependent variables were life satisfaction and migration attitude levels. Data were collected via an online questionnaire, incorporating the Brain Drain Attitude Scale (BDAS) and Life Satisfaction Scale (LSS), between April and May 2023. Results: The study found a negative correlation between nurses' life satisfaction levels and their attitudes toward migration (r = −.349, p <.001). Nurses dissatisfied with their profession (F = 6.575, p <.05), lacking professional support (F = 8.641, p <.05), and lacking social support (F = 6.307, p <.05) scored higher on the BDAS. Conversely, those satisfied with their profession (F = 31.455, p <.05), receiving professional support (F = 26.307, p <.05), and social support (F = 33.990, p <.05) scored higher on the LSS. Conclusion and implications for nursing: The study revealed that decreased life satisfaction among nurses in Turkey correlates with increased migration attitudes. These results underscore the need for strategies to enhance nurses' job satisfaction and support systems to mitigate migration tendencies. This study contributes valuable insights into the high inclination of Turkish nurses toward emigration.
- MakaleAçık Erişim2025Secondary Traumatic Stress and Coping Experiences in Psychiatric Nurses Caring for Trauma Victims: A Phenomenological Study
Gülirmak Güler, Kübra; Uzun, Sevda; Emirza, Elif Güzide
Aim: In this study, it was aimed to evaluate the secondary traumatic stress and coping experiences of psychiatric nurses who care for people who have experienced psychological trauma with a phenomenological approach. Materials and Methods: In this study, semi-structured in-depth interviews were conducted with 18 psychiatric nurses residing in Turkey using the phenomenological research method. The criterion sampling method was used to reach the sample group. Interviews continued until data saturation was achieved, and all interviews were audio-recorded and then transcribed. The data were analysed using thematic analysis. The study was conducted and reported using the COREQ checklist. Findings: In the analysis of the data, three themes (difficulties in caring for people who have experienced trauma, the effects of caring for people who have experienced trauma on the individual and coping, reflections of secondary trauma on the profession) and seven sub-themes (mental, physical, social, psychosocial difficulties and coping, quality of care, professional and organisational aspects) were identified. Conclusion: As a result of the study, it was determined that secondary traumatic stress was observed in psychiatric nurses caring for individuals who experienced psychological trauma. It was determined that caring for people who have experienced psychological trauma can negatively affect nurses psychosocially, and individuals have difficulty coping. In line with the results of the study, it is thought that necessary intervention programs should be created for nurses experiencing secondary traumatic stress.
- MakaleAçık Erişim2025The Effect of Music on Fear and Anxiety of Children During Tomography: A Randomized Controlled Double-Blind Study
Kurudirek, Fatma; Demir Barbak, Zülbiye; Demir İmamoğlu, Zeynep; Çiftci, Kamile; Delice, Orhan
Aim: This study was conducted to determine the effect of a musical intervention during computed tomography (CT) on fear, anxiety and vital signs of children. Method: This randomized, double-blind controlled trial was conducted according to the Consolidated Standards of Reporting Studies (CONSORT) guidelines. The study sample included children aged between 6 and 10 years who met the inclusion criteria and underwent CT scan in the emergency department of a public hospital in eastern Turkey between 18 April and 20 May 2023. The research was completed with a total of 60 children, randomized to one of two groups. The nursing intervention of the study was playing music. Data were collected through face-to-face interviews using the Child and Family Information Form, the Children's Fear Scale (CFS), Children's Anxiety Meter-State (CAM-S) and the Vital Signs Monitoring Form (pulse, blood pressure and oxygen saturation). Ethical principles were followed in the research. Results: The level of fear, anxiety, pulse rate and respiratory rate of the children in the musical intervention group during CT scanning were lower than in the control group (p < 0.05). No difference was found between the groups in terms of oxygen saturation (p < 0.05). Conclusion and Recommendations for Implementation: The results of this study suggest that musical intervention during CT scanning in children is effective in reducing the level of fear and anxiety and stabilizing vital signs. By using such nonpharmacologic methods, nurses can provide support to children and alleviate emotional difficulties during procedures. Trial Registration: NCT06086509. Summary: What is already known about this topic? Music therapy is recognized as an effective nonpharmacologic intervention to reduce fear and anxiety in paediatric patients undergoing medical procedures. Previous studies have shown that musical intervention during CT scans can calm children, potentially reducing the need for sedation and improving compliance. Knowledge gaps remain regarding the specific effects of music on physiological parameters like pulse and respiratory rates during paediatric CT scans. What this paper adds? This study demonstrates that musical intervention during CT scans significantly reduces fear and anxiety levels in children aged 6–10 years. The research findings show that music intervention can also stabilize vital signs, such as pulse and respiratory rates, during CT scans, suggesting a relaxed physiological state. The results support the idea that incorporating music into paediatric imaging procedures can enhance patient comfort and improve the quality of the imaging process by encouraging children to remain still. The implications of this paper: Incorporating music therapy into routine paediatric imaging procedures can reduce anxiety, improve patient cooperation and potentially reduce the need for sedatives. Future research could explore the optimal types of music, volume levels and delivery methods to maximize the calming effects on children during various medical procedures. Training programs for paediatric healthcare providers can include education on the benefits of nonpharmacologic interventions, like music therapy, to reduce anxiety and improve patient outcomes in clinical settings.
- MakaleAçık Erişim2025Internal Medicine Nurses’ Perceptions of Work Environment Ergonomics and Safety Climate
Aktepe Coşar, Dilan; Demirağ, Hatice
Objective: This study aimed to examine the relationship between the ergonomic conditions of the work environment and the perception of safety climate among internal medicine nurses. Materials and Methods: This descriptive study was conducted between October 30, 2023, and January 30, 2024, with a total of 440 internal medicine nurses in Turkey using the “snowball sampling” method. Data were collected using the “Personal Information Form,” the “Workplace Ergonomics Scale for Nurses,” and the “Safety Climate Scale.”. Results: A statistically significant difference was found in the mean scores of the “Workplace Ergonomics Scale for Nurses” based on marital status, educational level, perceived workload, and whether the nurses had received occupational safety training (p < 0.05). However, no significant difference was observed in the scale scores based on gender, professional experience, or satisfaction with the work environment (p > 0.05). A significant difference was also identified in the mean scores of the “Safety Climate Scale” according to gender, educational level, professional experience, satisfaction with the work environment, and occupational safety training status (p < 0.05). A significant negative correlation was found between the scores of the “Workplace Ergonomics Scale for Nurses” and its subdimensions and the safety training subdimension scores. Data were analyzed using t-test, ANOVA, and correlation analysis. Conclusion: In conclusion, improving ergonomic conditions, strengthening managerial support, establishing effective safety communication, and promoting continuous education are recommended as key strategies to ensure that nurses work in a safe and supportive environment. Additionally, implementing tailored interventions based on demographic and professional characteristics may contribute to the development of a safety culture in nursing and the improvement of patient care quality.
- MakaleAçık Erişim2025Safety and Nutritional Profile of Traditional Turkish Cheeses: A Comprehensive Study on Their Mineral Content, Heavy Metal Contamination, and Health Risks of Aho, Golot, and Telli
Erol, Seyit; Ürkek, Bayram
Traditional cheeses from Turkey's Black Sea region, such as Aho, Golot, and Telli, are widely known for their unique flavors and artisanal production methods. However, their microbiological safety, mineral content, and heavy metal contamination remain understudied. In this study, we evaluated 30 cheese samples for essential minerals and toxic heavy metals, alongside conducting a corresponding health risk assessment. The results of our mineral analysis revealed sodium (Na) levels ranging from 9787.79 to 37,902.22 mg/kg, while calcium (Ca) and magnesium (Mg) were present at nutritionally relevant concentrations. Heavy metals such as lead (Pb) and mercury (Hg) were detected, with Golot and Telli cheeses showing elevated levels (Pb: up to 1788.75 μg/kg; Hg: up to 468.71 μg/kg). Furthermore, health risk assessments, including estimated daily intake (EDI), target hazard quotient (THQ), and hazard index (HI), indicated that 93.3% of samples posed negligible risks (HI < 1), though two outliers (6.7%) exceeded safety thresholds. Taken together, these findings underscore the need for improved production processes in traditional cheese production while affirming their nutritional value and overall safety for consumers.
- MakaleAçık Erişim2025Evaluation of ChatGPT-4, Gemini, Claude, and Copilot in Generating Nursing Diagnoses Based on NANDA-I Taxonomy II: A Comparative Cross-Sectional Study
Tuncer, Metin; Yalcinkaya, Turgay
Aim: To evaluate the capability of large language models to generate nursing diagnoses based on NANDA-I Taxonomy II and assess their performance across domains and overall. Background: Large language models are emerging tools in nursing, showing potential to aid in diagnosis generation and education. However, their accuracy and applicability in clinical and educational settings remain underexplored. Methods: This cross-sectional comparative study used 10 realistic patient scenarios based on NANDA-I Taxonomy II, covering 12 domains. The study aimed to evaluate the capability of four models to generate nursing diagnoses based on patient scenarios. The responses were assessed by five nursing experts for accuracy and alignment with NANDA-I Taxonomy II in a single-blind evaluation process. Results: All models demonstrated similar performance across different domains and overall, with Claude attaining the highest overall performance score. Expert evaluations indicated moderate interrater reliability. Discussion: Small variations between models and occasional omissions suggest that expert review is still required before clinical use. Conclusions: Large language models are not yet sufficiently reliable for independent use in clinical settings and nursing education. Their application as supportive tools necessitates a cautious approach. Moreover, the development of specialized models designed to address the unique demands of the nursing field would be advantageous. Implications for nursing: When large language models are used in nursing practice, their limitations should be considered, and the outputs they produce should be verified by nurses. Implications for nursing policy: Ensuring the safe integration of artificial intelligence tools into nursing necessitates the establishment of robust regulatory policies to safeguard patient safety, the deployment of effective systems to monitor models’ performance, and the development of comprehensive guidelines and training programs.
- MakaleYalnız künye2025Inhibition Effect of Cordyceps sinensis (C. sinensis) Mycelium on Some Metabolic Enzymes and Investigation of Antioxidant Properties
Balcı, Neslihan
Cordyceps sinensis (CS), a traditional medicinal fungus, is a rich source of bioactive metabolites with pharmacological potential. This study investigated the inhibitory effects of CS mycelium on human carbonic anhydrase isoenzymes I and II (hCA I and hCA II) and acetylcholinesterase (AChE), as well as its antioxidant properties. Enzyme inhibition was assessed using spectrophotometric methods, whereas antioxidant capacity was evaluated by DPPH, ABTS, CUPRAC, FRAP, and Fe3⁺-reducing assays. LC-MS/MS analysis identified key secondary metabolites, including apigenin, apigenin-7-glucoside, (+)-taxifolin, dihydrokaempferol, p-coumaric acid, salicylic acid, and L-theanine, with apigenin as the major constituent. CS strongly inhibited hCA I (IC50 = 1.11 µg/mL) and hCA II (IC50 = 1.77 µg/mL), exceeding the potency of acetazolamide, and also showed relevant AChE inhibition (IC50 = 8.00 µg/mL), comparable to tacrine. Antioxidant assays revealed moderate DPPH activity but strong ABTS and CUPRAC reducing capacities, indicating the structural contributions of flavonoids and phenolic acids. These findings suggest that CS possess dual bioactivity through enzyme inhibition and antioxidant effects, highlighting its therapeutic potential against neurodegenerative and oxidative stress–related diseases.
- MakaleAçık Erişim2025Corrosion and structural properties of lightweight magnesium and aluminum alloy cores based sandwich composites
Keleş, Abdulsamet; Karabudak, Filiz; Acar, Volkan; Kula, M. Emin; Aslan, Mustafa; Karabacak, A. Hasan; Alibeyoğlu, Fatih
Metal plate core-based sandwich composites have the potential to revolutionize various industrial fields due to their mechanical strength and vibration damping. In this study, AZ91 (a magnesium alloy) and Al1050 (an aluminum alloy) metal core-based sandwich composites of AZ91/carbon fiber-epoxy, AZ91/glass fiber-epoxy, Al1050/carbon fiber-epoxy, and Al1050/glass fiber-epoxy sandwich composites were manufactured. These composites' mechanical and dynamic properties were determined through tensile, three-point bending, and vibration tests. AZ91-reinforced carbon fiber composites exhibited a 28.8% higher tensile strength than glass fiber composites, while Al1050-reinforced carbon fiber composites showed a 17.2% higher tensile strength performance than glass fiber composites. Moreover, AZ91 reinforcement led to composites with higher average flexural strength for both fibers. In vibration tests conducted under clamped and free-free boundary conditions, the highest first natural frequency was observed in AZ91/carbon fiber samples, sparking further interest. Conversely, the highest first damping ratio was observed in Al1050/glass fiber specimens. In addition, the corrosion behavior of sandwiches was evaluated, and it was found that glass fiber provided better corrosion resistance than carbon fiber. Highlights: Sandwich composites comprising AZ91/Al1050 cores and carbon/glass fiber reinforced epoxy face sheets were manufactured. Galvanic corrosion effects were evaluated, and glass fiber was found to provide higher corrosion resistance. AZ91/carbon fiber sandwich showed 28.8% higher tensile strength than glass fiber. Vibration tests revealed the AZ91/carbon fiber sandwich had the highest first natural frequency. Al1050/glass fiber sandwich exhibited the highest first damping ratio.
- MakaleAçık Erişim2025Screening of Chemical Profile by LC–MS/MS and Assessment of Biological Properties of Achillea sintenisii Hub. Mor. From Turkey
Köksal, Ekrem; Altay, Ahmet; Altın, Sevgi; Alp, Cemalettin; Ulutaş, Yakup; Şimşek, Samed; Karakuş, Sinem; Akyüz, Sümeyye; Aygül, İmdat; Akşit, Hüseyin
The aim of this study was to determine the secondary metabolites of the n-hexane, ethyl acetate, methanol, and water extracts of Achillea sintenisii Hub. Mor. and to ascertain their divergent biological properties. LC–MS/MS analysis was performed to identify the bioactive compounds. The anticancer properties of the samples were tested against human breast (MCF-7 and MDA-MB-453) and colon (HT-29) cancer cell lines by XTT assay. The anti-Alzheimer's studies were performed using Ellman's assay. The antimicrobial studies were carried out by Kirby–Bauer disc diffusion method. The antioxidative potential of the samples was evaluated on the basis of 2,2-diphenyl-1-picrylhydrazyl scavenging and ferric reducing antioxidant power assays, LC–MS/MS analysis revealed 27 phytochemicals, including high concentrations of quinic acid, gentisic acid, chlorogenic acid, luteolin, cynaroside, and caffeic acid. Ethyl acetate extract exhibited the most potent cytoxicity against MDA-MB-453 cells, with an IC50 value of 83.05 µg/mL. All extracts showed stronger inhibitory activity against acetylcholinesterase and butyrylcholinesterase compared to tacrine. The n-hexane, ethyl acetate, and methanol extracts exhibited considerable antimicrobial activity against Enterococcus faecalis, approaching the level of vancomycin. Methanol extract possessed the highest DPPH scavenging and ferric reducing antioxidant power. These findings render A, sintenisii a promising source for the pharmaceutical, cosmetic, and food industries.