Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(46)
- Kulakaç, Nurşen(21)
- Aydin, Aydanur(16)
- Demir, Selim(16)
- Tuncer, Metin(16)
- Topal, Fevzi(15)
- Turan, Ibrahim(15)
- Yilmaz, Coskun(14)
- Bayrakdaroglu, Serdar(12)
- Koçak, Tevfik(11)
- Aliyazicioglu, Yuksel(10)
- Gulcin, Ilhami(10)
- Ozturk, Samet(10)
- Topal, Meryem(10)
- Ceylan, Halil Ibrahim(9)
- Ceylan, Levent(9)
- Kilinc, Kagan(9)
- Mentese, Ahmet(9)
- Ozdes, Duygu(9)
- Tuncer, Gülsüm Zekiye(9)
- Duran, Celal(8)
- Emirza, Elif Güzide(8)
- Yaman, Serap Ozer(8)
- Yılmaz, Coşkun(8)
- Baltacı, Cemalettin(7)
- Demirağ, Hatice(7)
- Hintistan, Sevilay(7)
- Kaya, Feridun(7)
- Küçük, Murat(7)
- Ürkek, Bayram(7)
- Şengül, Mustafa(7)
- Bayrakdaroğlu, Serdar(6)
- Deger, Orhan(6)
- Genc, Berna(6)
- Gül, Abdulkadir(6)
- Gülçin, Ilhami(6)
- Günen, Mehmet Akif(6)
- Gürsoy, Ayla(6)
- Kurnaz, Muammer(6)
- Supuran, Claudiu T.(6)
Yayınlar
- MakaleAçık Erişim2022Scopus SJRQ1The image of nursing among nursing and other healthcare professional university students: A mixed-method study
Apaydin Cirik, Vildan; Gül, Uğur; Aksoy, Bahar
Aim: This study had three objectives: (1) determining the image of nursing in the eyes of undergraduate health sciences students; (2) identifying factors affecting that image; and (3) evaluating students’ views and experiences regarding that image. Background: If healthcare students perceive nursing positively, it may result in directing future generations to nursing, and improving nursing, and reducing the need for nurses. Design: This study adopted an explanatory sequential design with participant selection variant. The design involved data collection in two consecutive phases. Methods: A mixed-method design using quantitative data and qualitative interviews was used. In the quantitative phase, a descriptive and cross-sectional research method was used. The qualitative phase was based on phenomenological research. The quantitative portion was performed with 1556 participants in their second, third or fourth year during the 2019–2020 academic year. Students were from the nursing, emergency and disaster management, nutrition and dietetics, occupational health and safety, health management, and social work departments. The qualitative portion was performed with 29 participant volunteers. Participants were interviewed on the phone. The data were collected using an introductory information form, a nursing image scale, and semi-structured interviews. The quantitative data were analyzed using descriptive statistics and the independent-samples t-test, Mann-Whitney U test, one-way ANOVA, and stepwise linear regression. The quantitative data were analyzed using thematic analysis. Results: There were significant relationships between participants' nursing image scale total scores and their department (p < 0.001), education year (p = 0.014), age (p = 0.032) and desire to recommend the nursing profession (p < 0.001). Nursing image scale total score was significantly higher in nursing departments than in other departments. Second-year participants and 18–20-year-olds had higher total scores than fourth-year participants and 21–23-year-olds, respectively, and those who would recommend the nursing profession had higher total scores than those who would not recommend it (p < 0.05). Analysis of the qualitative data produced six main themes: perceptions of the nursing profession, perceived nursing figure, nurse knowledge, relationship with healthcare professionals, reason for preference and job gender. Conclusion: This study employed a mixed-method design involving both quantitative and qualitative stages. The results highlighted the image of nursing and its significance in the eyes of prospective healthcare professionals. Detecting nursing image early can increase professional training and improve the professional image of nursing. We should take into account the factors that negatively affect the image of nursing to plan nursing education better in the future.
AtıfScopus26WoS21OpenAlex25İncele - MakaleYalnız künye2022Scopus SJRQ2An Investigation of the Antiproliferative Effect of Rhododendron luteum Extract on Cervical Cancer (HeLa) Cells via Nrf2 Signaling Pathway
Turan, Ibrahim; Demir, Selim; Yaman, Serap Ozer; Canbolat, Deniz; Mentese, Ahmet; Aliyazicioglu, Yuksel
The aim of the present study was to investigate the role of Rhododendron luteum extract (RLE) in the induction of Nrf2‑related oxidative stress and endoplasmic reticulum (ER) stress in human cervical cancer (HeLa) cells. The antiproliferative effect of RLE on HeLa and fibroblast cells was determined using the MTT assay. The effects of RLE on the cell cycle, apoptosis, and production of reactive oxygen species (ROS) in HeLa cells were evaluated using fluorescent probes. The mRNA expression levels of Nrf2 [and its targets glutamate-cysteine ligase catalytic subunit (GCLC), and glucose-6-phosphate dehydrogenase (G6PD)], and C/EBP homologous protein (CHOP, an ER stress marker were determined using reverse transcription‑quantitative polymerase chain reaction (RT-PCR). The results demonstrated that RLE exhibited a selective cytotoxic effect (2.9-fold) on HeLa cells compared to fibroblast cells. RLE arrested the cell cycle at the S phase, and induced apoptosis, ER stress, and ROS formation. In addition, RLE significantly suppressed the expression levels of Nrf2, GCLC and G6PD (0.65, 0.69, and 0.54-fold, respectively) and increased the expression of CHOP (4.48-fold) in HeLa cells at 72 h of treatment (p < 0.05). These results show that the antiproliferative effect of RLE occurs through the Nrf2 and ER stress pathways, and the results should now be supported by further in vivo studies.
AtıfScopus15WoS15OpenAlex13İncele - MakaleYalnız künye2022Scopus SJRQ2Hidden Diversity in a Narrow Valley: Description of New Endemic Palearctic Rock Lizard Darevskia (Squamata: Lacertidae) Species from Northeastern Turkey
Kurnaz, Muammer; Şahin, Mehmet Kürşat; Eroğlu, Ali İhsan
Darevskia is a particularly species-rich radiation of Palearctic rock lizards from the Caucasus region. Thanks to intense systematic and taxonomic research, the knowledge of species-level diversity within this genus has increased over the last quarter century. Here, we described a new species, Darevskia salihae sp. nov. from northeastern Turkey. The new taxon is differentiated from other nearby taxon by the low number of dorsal scales in the middle of the body, the shorter body length, and the absence of blue dots both on the lateral region above the forelimbs and on the margin of the ventral plates. In addition to their morphological differences, the new taxon is phylogenetically different from close groups. It is located in a separate subclade from the rudis-valentini-portschinskii subclade. This distinction is supported by both a high bootstrap value (100) and a high posterior probability value (1.00). These two subclades are separated from each other by a genetic distance of almost 4%. This separation is supported not only genetically and morphologically, but also geographically. Since the habitat of the new taxon is limited to a high mountain and a narrow valley, it does not provide an opportunity for a different Darevskia species to shelter because it creates geographical isolation. However, Darevskia parvula that live closest to the habitat of the new taxon live only at the habitat boundaries and do not enter areas where the new taxon is found. Therefore, it might be possible that while it was separated from the rudis-valentini-portschinskii group during the evolutionary transformation, it remained as a refuge and relict in a narrow area as a result of the collapse of the valleys and the partial uplift of the Kaçkar Mountains.
AtıfScopus6WoS5OpenAlex4İncele - MakaleAçık Erişim2022Scopus SJRQ2The effect of the COVID-19 pandemic on the professional perception and image of nursing among nurses working in surgical units: An online study
Sayilan, Aylin Aydin; Kulakac, Nursen
BACKGROUND: Understanding the effects of the COVID-19 pandemic on the perception and image of the profession are key factors in nurses' perceptions regarding their roles and their future. OBJECTIVE: The purpose of this study was to determine the effect of the COVID-19 pandemic on the perception and image of the nursing profession among nurses working in surgical units. METHODS: This cross-sectional, correlational study was conducted with 216 nurses using the random sampling method between 10 and 30 March, 2022. The study data were collected using an information form, the Perception of Nursing Professional Scale (PNPS), and the Scale for the Image of the Nursing Profession. RESULTS: The nurses' mean age was 32.53±9.16 years (min 21, max 57) and their mean professional experience was 16.44±9.80 years (min 1, max 44). The mean PNPS score was 73.12±9.46, and the mean Scale for the Image of the Nursing Profession score was 171.11±11.16. Female nurses had significantly higher positive perceptions of nursing levels than male nurses. Gender, having a history of COVID-19, marginalization during the pandemic, and perception of the nursing profession significantly affected image perceptions of nursing at multiple linear regression analysis. These variables explained 43% of the total variance. CONCLUSION: Nurses working in surgical units during the COVID-19 pandemic exhibited a good level of professionalism and image perception concerning nursing.
AtıfScopus4OpenAlex2İncele - MakaleAçık Erişim2022Scopus SJRQ2The effect of motivational interview conducted by nurses on quality of life: Meta-analysis
Uzun, Sevda; Özmaya, Esma
Purpose: The aim of the study is to examine the effect of the motivational interviewing method conducted by nurses on the quality of life of patients with chronic diseases. Design and Methods: The studies examined in this meta-analysis study were obtained by scanning the PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK thesis databases between January and May 2021 without any year limitation. After the elimination, 16 studies were included in the study. The data were synthesized with meta-analysis and narrative methods. The total sample size of the studies was 14,425. Findings: This meta-analysis demonstrated that the motivational interviewing method applied by nurses in individuals with chronic diseases changed their quality of life (SMD: 0.258, 95% confidence interval: 0.076–0.441; Z = 2.775, p = 0.006, I2 = 89.97%). The variance between studies was statistically significant (p < 0.05) for the moderator of the measurement tools, the duration of the motivational interviews, and the country/continent of the studies were conducted (p < 0.05), suggesting that the measurement tools, the duration of the motivational interview, and the country/continent of the studies changed the effect size of the motivational interview method on the quality of life. Practice Implications: It has been concluded that the motivational interview method applied by nurses who are in a critical position in the protection and development of health improves the quality of life of individuals with chronic diseases.
AtıfScopus4WoS4OpenAlex5İncele - MakaleAçık Erişim2022Scopus SJRQ2Comparison of the relationship between menopausal symptoms and loneliness and anger
Ozcan, Handan; Savci, Hamit; Canik, Muhammed; Ayan, Mahsun; Bas, Cağla Firdevs
Purpose: This study aimed to determine the relationship between the symptoms of anger and loneliness among women in the menopausal period. Design and Methods: A total of 200 women in the menopausal period were interviewed within the scope of this study. Descriptive Information Form, UCLA Loneliness Scale, Trait Anger and Anger Expression Scale and Menopause-Specific Quality of Life Questionnaire were used to collect data. Findings: The mean score of the UCLA Loneliness Scale was found as 53.61 ± 7.68 and it was observed that the participants had high traits of anger and a high-level of loneliness. Loneliness and anger increase when menopausal symptoms increase in women. Practice Implications: Menopause is generally perceived by women as a troublesome period instead of being a normal life process. In order for women to spend this period at a more comfortable and desirable level, it is important to know cultural characteristics, social support systems, coping mechanisms.
AtıfScopus7WoS6OpenAlex8İncele - MakaleYalnız künye2022Scopus SJRQ3Evaluation of the relationship between health literacy and self-efficacy: A sample of hemodialysis patients
Kazak, Aysun; Özkaraman, Ayşe; Topalı, Hasret; Duran, Secil
Purpose: The aim of this study was to evaluate self-efficacy and health literacy of patients undergoing hemodialysis, to investigate the relationship between health literacy and self-efficacy, and to determine the factors affecting self-efficacy. Methods: The study was conducted in Eskisehir and Gumushane state hospitals affiliated to the Public Hospitals Association with the participation of 198 patients receiving hemodialysis treatment for chronic renal failure. The inclusion criteria were as follows: being ⩾18 years old, receiving hemodialysis, and agreeing to participate in the study. The study data were collected using face-to-face interview technique, and they were analyzed using descriptive statistics, correlation, and regression analysis. Results: The mean age of the patients was 59.73 ± 16.32 years. Of the patients, 46% were primary school graduates, and 63.6% reported having other chronic diseases. The mean health literacy and self-efficacy scores were found to be 79.43 ± 26.09 and 23.98 ± 7.42, respectively. The results showed that the self-efficacy scores of the patients increased as the general health literacy scores increased, with a strong linear correlation between these variables (r = 0.712; p ˂ 0.001). Patients with advanced age, low educational level, and widowed patients had lower self-efficacy and health literacy scores than others (respectively eta2 = 0.263, 0.116, 0.268, 0.141). Conclusion: High score of health literacy positively affects the self-efficacy score of hemodialysis patients.
AtıfScopus8WoS8İncele - MakaleYalnız künye2022Scopus SJRQ2The relationship between the risk of eating disorder and meal patterns in University students
Kabakuş Aykut, Memnune; Bilici, Saniye
Purpose: This study was carried out to evaluate the relation between meal patterns and the risk of eating disorders in university students. Methods: The study was conducted on a total of 331 volunteer students with a mean age of 22.08 ± 1.80 years, 56.5% female. Participants’ sociodemographic characteristics, health information and eating habits like meal skipping and dieting were questioned. Sick, Control, One stone, Fat, Food (SCOFF) Eating Disorders Scale and Eating Disorder Examination Questionnaire (EDE-Q) were used to determine eating behavior disorders, with face to face interviews by the researches. Results: A significant correlation was found between dieting and skipping meals and the risk of eating disorders in both genders (p < 0.05). In addition, when the reasons for skipping meals were questioned, a significant relationship was detected between skipping meals and eating behaviour disorders by 3.285 times (p = 0.000). Also, every unit of increase in body mass index (BMI) values of individuals who participated to the study led to an increase in eating disorders by a factor of 1.262 (p = 0.000). Conclusions: Our findings support concerns about the negative health effects of increasing overweight among university students in accordance with the data that the increase in BMI values led to an increase in eating disorders. Notably a significant correlation was found between dieting, skipping meals and the risk of eating disorders in both genders it is highlighting the need for monitoring and early diagnosis of eating disorders in youth with simple scales like SCOFF. Level of evidence: Level V, cross-sectional descriptive study.
AtıfScopus19WoS17OpenAlex26İncele - MakaleYalnız künye2022Scopus SJRQ2InSiNet: a deep convolutional approach to skin cancer detection and segmentation
Reis, Hatice Catal; Turk, Veysel; Khoshelham, Kourosh; Kaya, Serhat
Cancer is among the common causes of death around the world. Skin cancer is one of the most lethal types of cancer. Early diagnosis and treatment are vital in skin cancer. In addition to traditional methods, method such as deep learning is frequently used to diagnose and classify the disease. Expert experience plays a major role in diagnosing skin cancer. Therefore, for more reliable results in the diagnosis of skin lesions, deep learning algorithms can help in the correct diagnosis. In this study, we propose InSiNet, a deep learning-based convolutional neural network to detect benign and malignant lesions. The performance of the method is tested on International Skin Imaging Collaboration HAM10000 images (ISIC 2018), ISIC 2019, and ISIC 2020, under the same conditions. The computation time and accuracy comparison analysis was performed between the proposed algorithm and other machine learning techniques (GoogleNet, DenseNet-201, ResNet152V2, EfficientNetB0, RBF-support vector machine, logistic regression, and random forest). The results show that the developed InSiNet architecture outperforms the other methods achieving an accuracy of 94.59%, 91.89%, and 90.54% in ISIC 2018, 2019, and 2020 datasets, respectively. Since the deep learning algorithms eliminate the human factor during diagnosis, they can give reliable results in addition to traditional methods. Graphical abstract: [Figure not available: see fulltext.]
AtıfScopus170WoS313OpenAlex160İncele - MakaleYalnız künye2022Scopus SJRQ3Roza: a new and comprehensive metric for evaluating classification systems
Melek, Mesut; Melek, Negin
Many metrics such as accuracy rate (ACC), area under curve (AUC), Jaccard index (JI), and Cohen’s kappa coefficient are available to measure the success of the system in pattern recognition and machine/deep learning systems. However, the superiority of one system to one other cannot be determined based on the mentioned metrics. This is because such a system can be successful using one metric, but not the other ones. Moreover, such metrics are insufficient when the number of samples in the classes is unequal (imbalanced data). In this case, naturally, by using these metrics, a sensible comparison cannot be made between two given systems. In the present study, the comprehensive, fair, and accurate Roza (Roza means rose in Persian. When different permutations of the metrics used are superimposed in a polygon format, it looks like a flower, so we named it Roza.) metric is introduced for evaluating classification systems. This metric, which facilitates the comparison of systems, expresses the summary of many metrics with a single value. To verify the stability and validity of the metric and to conduct a comprehensive, fair, and accurate comparison between the systems, the Roza metric of the systems tested under the same conditions are calculated and comparisons are made. For this, systems tested with three different strategies on three different datasets are considered. The results show that the performance of the system can be summarized by a single value and the Roza metric can be used in all systems that include classification processes, as a powerful metric.
AtıfScopus7WoS8OpenAlex9İncele - MakaleAçık Erişim2022Scopus SJRQ1COVID-DSNet: A novel deep convolutional neural network for detection of coronavirus (SARS-CoV-2) cases from CT and Chest X-Ray images
Reis, Hatice Catal; Turk, Veysel
COVID-19 (SARS-CoV-2), which causes acute respiratory syndrome, is a contagious and deadly disease that has devastating effects on society and human life. COVID-19 can cause serious complications, especially in patients with pre-existing chronic health problems such as diabetes, hypertension, lung cancer, weakened immune systems, and the elderly. The most critical step in the fight against COVID-19 is the rapid diagnosis of infected patients. Computed Tomography (CT), chest X-ray (CXR), and RT-PCR diagnostic kits are frequently used to diagnose the disease. However, due to difficulties such as the inadequacy of RT-PCR test kits and false negative (FN) results in the early stages of the disease, the time-consuming examination of medical images obtained from CT and CXR imaging techniques by specialists/doctors, and the increasing workload on specialists, it is challenging to detect COVID-19. Therefore, researchers have suggested searching for new methods in COVID- 19 detection. In analysis studies with CT and CXR radiography images, it was determined that COVID-19-infected patients experienced abnormalities related to COVID-19. The anomalies observed here are the primary motivation for artificial intelligence researchers to develop COVID-19 detection applications with deep convolutional neural networks. Here, convolutional neural network-based deep learning algorithms from artificial intelligence technologies with high discrimination capabilities can be considered as an alternative approach in the disease detection process. This study proposes a deep convolutional neural network, COVID-DSNet, to diagnose typical pneumonia (bacterial, viral) and COVID-19 diseases from CT, CXR, hybrid CT + CXR images. In the multi-classification study with the CT dataset, 97.60 % accuracy and 97.60 % sensitivity values were obtained from the COVID-DSNet model, and 100 %, 96.30 %, and 96.58 % sensitivity values were obtained in the detection of typical, common pneumonia and COVID-19, respectively. The proposed model is an economical, practical deep learning network that data scientists can benefit from and develop. Although it is not a definitive solution in disease diagnosis, it may help experts as it produces successful results in detecting pneumonia and COVID-19.
AtıfScopus36WoS22OpenAlex36İncele - MakaleAçık Erişim2022Scopus SJRQ1A countrywide analysis of 27 solar power plants installed at different climates
Ozden, Talat
The world is still heavily using nonconventional energy sources, which are worryingly based on carbon. The step is now alternative energy sources hoping that they will be more environmentally friendly. One of the important energy conversion forms by using these sources is photovoltaic solar systems. These type of power plants is on the increase in everyday on the world. Before investment a solar power plant in a specified region, a techno-economic analyse is performed for that power plant by using several meteorological data like solar irradiance and ambient temperature. However, this analyses generally lacks evaluation on effects of climatic and geographical conditions. In this work, 5 years of data of 27 grid-connected photovoltaic power plants are investigated, which are installed on seven different climate types in Turkey. Firstly, the power plants are categorized considering the tilt angles and Köppen–Gieger climate classification. The performance evaluations of the plants are mainly conducted using monthly average efficiencies and specific yields. The monthly average efficiencies, which were classified using the tilts and climate types were from 12 to 17%, from 12 to 16% and from 13 to 15% for tilts 30°/10°, 25° and 20°, respectively. The variation in the specific yields decrease with elevation as y(x) = − 0.068x + 1707.29 (kWh/kWp). As the performances of photovoltaic systems for some locations within the Csb climatic regions may relatively lower than some other regions with same climate type. Thus, techno-economic performance for PVPP located in this climate classification should be carefully treated.
AtıfScopus6WoS2OpenAlex8İncele - MakaleAçık Erişim2022Scopus SJRQ1Warm up with music and visual feedback can effect Wingate performance in futsal players
Bayrakdaroglu, Serdar; Eken, Oezgur; Yagin, Fatma Hilal; Bayer, Ramazan; Gulu, Mehmet; Akyildiz, Zeki; Nobari, Hadi
Purpose: Visual feedback and music while warm up may help elicit peak performance, but its effect during the Wingate anaerobic test (WAnT) in futsal players is unexplored. Therefore, the aim of this study was to examine the effects of music and visual stimulus on WAnT performance in futsal players. Methods: The study included 17 young male futsal players (age, 21.53 +/- 1.32 years; height, 177.59 +/- 5.75 cm; 73.71 +/- 9.31 kg; BMI 23.342 +/- .47). The WAnT was administered using three distinct protocols: with music (M), without music (NM), and with music and visual feedback (MV) following a 10-min warm-up at 72-h intervals. After WAnT, the following parameters were evaluated: (a) peak power output: PPO (W), (b) relative peak power output: RPPO (W/kg), (c) mean power output: MPO (W), (d) relative mean power output: RMPO (W/kg), (e) fatigue index: FI (%), and (f) minimum power output MIPO (W). Results: MV indicated that futsal players' WAnT values, including PPO, RPPO, MPO, RMPO, and MIPO improved more than with other protocols (p < 0.05). However, there was no significant difference between protocols for FI (%) WAnT values (p > 0.05). Conclusions: Listening to music and watching visual feedback while warm up before performing WAnT performance suggest to coaches and futsal players.
AtıfScopus6WoS5OpenAlex12İncele - MakaleAçık Erişim2022Scopus SJRQ1Diurnal variation in Uchikomi fitness test performance: Influence of warm-up protocols
Eken, Oezguer; Yagin, Fatma Hilal; Eken, Ismihan; Gabrys, Tomasz; Knappova, Vera; Bayrakdaroglu, Serdar; Akyildiz, Zeki; Nobari, Hadi
Performance is judged using a variety of methods to ensure uniformity between competitions. Uchikomi Fitness Test (UFT) could accomplished between morning qualifying and evening finals. The purpose of this study is to investigate the impact of different warm-up protocols on UFT at different times of the day in female judokas. Ten volunteer women who had been practising judo on a regular basis for more than 5 years and actively competed in international tournaments took part in this study. Judokas completed UFT, either after no-warm-up (NWU), specific warm-up (SWU), and linear+lateral warm-up (FWU) protocols for two times a day in the morning: 09:00-11:00 and in the evening: 16:00-18:00, on non-consecutive days. In conclusion, there was a significant increase in UFT scores (F = 9.89; p = 0.002), a + b (F = 4.42; p = 0.04) and heart rate (F = 28.99; p < 0.001) in the early evening compared to the morning. Increases in UFT performance were observed in the SWU protocol compared to the NWU and FWU protocols (p < 0.05). However, the interaction between time of day and warm protocol was not significant (p > 0.05). The UFT performance revealed diurnal variation, and the judokas' performances may be favourably affected more in the late hours, particularly following SWU procedures.
AtıfScopus9WoS7OpenAlex8İncele - MakaleAçık Erişim2022Scopus SJRQ1The concept of pain inventory for children: The reliability and validity study of the Turkish version
Cirik, Vildan Apaydin; Bulut, Elif; Aksoy, Bahar; Coemert, Hatice Sonay Yalcin; Pate, Joshua W.
Background and purpose: Pain experiences in childhood are very likely to be reflected in adulthood. The early evaluation of the concept of pain in children may eventually lead to.better patient outcomes in the future. Therefore, we aimed to culturally and developmentally adapt the Concept of Pain Inventory for Children (COPI) for Turkish children.Methods: This descriptive, correlational study was conducted with 239 post-operative children aged 8-12 years between June and December 2021. The research adhered to COSMIN guidelines. The data were collected using a descriptive information form and the COPI. Factor analysis, Cronbach's alpha, and item-total score analysis were used for the data analysis.Results: The resulting unidimensional scale consists of 12 items in Turkish. The scale explained 65% of the total variance. The exploratory factor analysis showed that the factor loadings of items ranged from 0.64 to 0.91. The confirmatory factor analysis showed that the factor loadings of items ranged from 0.66 to 0.92. Goodness of fit indexes were found to be as follows: Normed Fit Index >0.90; Incremental Fit Index >0.90; Comparative Fit Index >0.90; and the Root Mean Square Error of Approximation <0.08. The total Cronbach's alpha coefficient of the scale was 0.78 (reliable). Conclusions: The 12-item Turkish translation of the COPI was deemed valid and reliable in 8-12-year-old children in a post-operative setting. Practice implications: Evaluation of children's pain concepts during childhood may contribute to the identification of conceptual gaps for pain science education.(c) 2022 Elsevier Inc. All rights reserved.
AtıfScopus4WoS4OpenAlex5İncele - MakaleAçık Erişim2021Scopus SJRQ1Chemical compositions by using LC-MS/MS and GC-MS and antioxidant activities of methanolic extracts from leaf and flower parts of Scabiosa columbaria subsp. columbaria var. columbaria L.
Akar, Zeynep
The members of the Scabiosa genus are one of the traditional medicinal plants used in the treatment of many diseases, in particular the treatment of scabies. In this study, it was aimed to determine antioxidant activities and chemical composition of methanolic extracts of leaves and flowers of Scabiosa columbaria subsp. columbaria var. columbaria. The phenolic contents of both parts of the plant were analyzed by LC-MS/MS. A total of 6 phenolic compounds were determined and chlorogenic acid was the major compound in both flower and leaf parts of the plants, with 5936.052 mg/g and 8021.666 mg/g, respectively. 6 different methods were used to determine the antioxidant activity of the plant parts. Both leaf and flower parts of the plant showed high antioxidant activity in all tested methods and the antioxidant activity values of the leaf part were measured higher than those of the flower part for four tests. The methanol extracts of the plant parts was analyzed with GC-MS and number of the essential oil compounds in the leaf and flower parts were determined as 17 and 13, respectively. Linalool compound was also found to be common in both parts of the plant. The major compounds of the essential oils were identified as 4Octadecenal (30.01%) in the flower and carvone (35.44%) in the leaf. In addition, terpene derivatives was determined as 90.32% of the highest essential oil group in the leaf, while this value was determined as 1.42% in the flower. For the flower, aromatics were determined as the main component group with 21.31%. (c) 2021 The Author. Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
AtıfWoS22OpenAlex29İncele - MakaleYalnız künye2021Scopus SJRQ2In vitro Antioxidant and Cytotoxic Activities of Extracts of Endemic Tanacetum erzincanense Together with Phenolic Content by LC-ESI-QTOF-MS
Yapıcı, İsmail; Altay, Ahmet; Öztürk Sarıkaya, Beyza; Korkmaz, Mustafa; Atila, Alptuğ; Gülçin, İlhami; Köksal, Ekrem
In this study, phenolic composition, and in vitro biological activities of ethyl acetate (EAE) and methanol (ME) extracts obtained from the aerial parts of endemic Tanacetum erzincanense were investigated. Total phenolic and flavonoid content of the extracts were determined by Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. Antioxidant capacity of the extracts was evaluated over radical scavenging (DPPH and ABTS) and metal ion reducing power (FRAP and CUPRAC) tests. Individual phenolic compounds in ME was analyzed by high-performance liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF/MS). Cell inhibitory potential of the extracts was tested against colorectal adenocarcinoma (HT-29), breast adenocarcinoma (MCF-7), and hepatocarcinoma (HepG2) cells by 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. The results showed that ME contains higher TPC (64.4 mg GAE/g) and TFC (62.2 mg QE/g) than those of EAE (41.5 mg GAE/g and 40.0 mg QE/g). LC-ESI-QTOF/MS analysis revealed that ME is rich in phenolic compounds, namely, chlorogenic acid, apigenin, quercetin, luteolin, and diosmetin. Antioxidant assay results indicated that ME possess stronger activity than EAE and a power that competes with synthetic antioxidants. XTT assay results demonstrated that although both extracts displayed a considerable cytotoxicity against the tested cancer cell lines in a time and dose-dependent manner, ME expressed its selective inhibitory action towards MCF-7 cells with an IC50 value of 20.4 μg/mL for 72 h. These results may serve as a basis for further in vivo studies to examine the potential applications of T. erzincanense in food and pharmaceutical industries.
AtıfScopus27WoS24OpenAlex24İncele - MakaleAçık Erişim2021Scopus SJRQ3Antibiotic induced biofilm formation of novel multidrug resistant Acinetobacter baumannii ST2121 clone
Çimen, Müberra; Düzgün, Azer Özad
The aim of this study was to identify antimicrobial resistance and virulence factor genes exhibited by multidrug resistant (MDR) Acinetobacter baumannii, to analyze biofilm formation and to investigate clonal subtypes of isolate. Whole genome sequencing was done by Illumina NovaSeq 6,000 platform and multilocus sequence typing (MLST) was performed by Oxford and Pasteur typing schemes. Influence of imipenem and levofloxacin on biofilm formation was investigated in 96-well plates at 3 replicates. The strain was found to carry OXA-23, OXA-51-like, AmpC and TEM-1 beta-lactamases. The sequence of the blaOXA-51-like gene has been identified as a blaOXA-66. According to Pasteur MLST scheme the strain displayed ST2 allelic profile. However, based on Oxford MLST scheme this strain represents the new ST2121, as the gdhB gene has a single allelic mutation namely, the gdhB-227. It was determined that MDR isolate carried bap, basABCDFGHIJ, csuA/BABCDE, bauABCDEF, plcD, pgaABCD, entE, barAB, ompA, abaIR, piT2EAFTE/AUBl, fimADT, cvaC, bfmR, bfmS virulence genes. In our study imipenem induced the highest biofilm formation at a concentration of 32 mg/ml and levofloxacin at a concentration of 16 mg/ml. In conclusion, we detected a new MDR A. baumannii ST2121 clone harboring blaOXA-66 gene that has been reported for the first time in Turkey.
AtıfScopus7WoS7OpenAlex11İncele - MakaleYalnız künye2021Scopus SJRQ1Mineral content, fatty acid composition, and volatile compounds of gluten-free tarhana formulated with different cereal and pulse flours
Çalışkan Koç, Gülşah; Tekgül, Yeliz; Erten, Edibe Seda; Akdoğan, Arda
Abstract: This research was intended to determine the effect of different cereal and pulse flours and commercial gluten-free flour on the mineral content, fatty acid composition, and volatile compounds of the gluten-free tarhana (cereal-based fermented dry soup). In order to produce the gluten-free tarhana, white bean (BF), chickpea (CF), commercial gluten-free (GWF), yellow lentil (LF), and rice (RF) flours were used. The Mg, K, Al, and Mn contents of tarhanas obtained using different pulse and cereal flours were found to be quite high compared to tarhanas produced with commercial GWF. The utilization of different cereal and pulse flours in the tarhana formulation resulted in an increase in the percentage (30.37–51.47%) of the total polyunsaturated fatty acid (TPUFA). The highest (452.4 µg/g) and the lowest (241.17 µg/g) total concentration of all compounds were detected in BF and GWF, respectively. The highest number (21) of compounds belonged to terpenes and terpenoids, followed by acids, hydrocarbons, alcohols, aldehydes, esters, ketones, and alkanes. Practical Application: This study shows that cereal and pulse flours can be used to produce acceptable tarhana with improved nutritional quality in terms of mineral and fatty acid contents. The results of the current study may be useful and applicable to food manufacturers producing gluten-free products for celiac patients.
AtıfScopus12WoS10OpenAlex11İncele - MakaleYayıncıda açık erişim2021Scopus SJRQ1Factors affecting nurses' professional commitment during the COVID-19 pandemic: A cross-sectional study
Duran, Secil; Celik, Isa; Ertugrul, Bekir; Ok, Serife; Albayrak, Sevil
Aim: This study aims to investigate the factors affecting nurses' professional commitment during the COVID-19 pandemic. Background: Commitment to a profession requires doing the best for that profession. In the case of the nursing profession, professional commitment gains greater importance in times of crisis, like the COVID-19 pandemic. Methods: This cross-sectional study was conducted with 389 nurses in the Turkish state hospital. Institutional permissions, ethical approval and written consents from the participants were obtained before carrying out the study. Results: The participants’ mean Perceived Organizational Obstruction Scale score was 20.07 ± 8.06 (min = 5.0, max = 35.0), and their mean Nursing Professional Commitment Scale score was 71.20 ± 11.94 (min = 30.0, max = 103.0). Socio-demographic variables and perception of organisational obstruction predicted 36.7% of the variance in the professional commitment (p <.001). Conclusion: A road map based on the study results was developed for hospitals and nurse managers to maintain and increase nurses' professional commitment. Implications for Nursing Management: The results of this study may help institutions and nurse managers understand the factors affecting professional commitment during the pandemic as a whole, as well as determine primary strategies based on the importance of these factors.
AtıfScopus69WoS55OpenAlex88İncele