Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Kulakaç, Nurşen(10)
- Çelik, Orkun(8)
- Ashyralyyev, Charyyar(7)
- Keyifli, Nazlı(7)
- Ashyralyev, A.(6)
- Kayikcioglu, Temel(6)
- Menevseoglu, Ahmed(6)
- Araz, Onur(5)
- Ashyralyyev, C.(5)
- Demirbağ, Orkun(5)
- Koç, Pinar(5)
- Turan, Ibrahim(5)
- Ünlü, Ramazan(5)
- Ürkek, Bayram(5)
- Akar, Zeynep(4)
- Akyol, Hikmet(4)
- Akyol, Mehmet(4)
- Aydınçakır, Emre(4)
- Bilgilioglu, Burhan Baha(4)
- Demir Doğan, Melike(4)
- Demir, Selim(4)
- Kankal, Murat(4)
- Kurnaz, Muammer(4)
- Melek, Mesut(4)
- Pala, Fahrettin(4)
- Sancar Özkök, Canan(4)
- Taş, Ahmet(4)
- Ulutaşdemir, Nilgün(4)
- Uzun, Sevda(4)
- Acet, Tuba(3)
- Akay, K.U.(3)
- Aydin Sayilan, Aylin(3)
- Aydın Sayılan, Aylin(3)
- Barut, Abdulkadir(3)
- Basoglu, Mustafa Engin(3)
- Cakalli, H.(3)
- Canak, I.(3)
- Cengiz, Ekrem(3)
- Cengiz, Emre(3)
- Cengiz, Sevil(3)
Yayınlar
- MakaleYalnız künye2021Scopus SJRQ2Comparison of the effects of operating microscopes with light emitting diode and halogen light source on the eye: a rabbit study
Aydin, Bahir; Ozgur, Armagan; Ozdemir, Huseyin Baran; Inan, Mehmet Arda; Atalay, Hatice Tuba; Bayrakceken, Kemal; Ozmen, Mehmet Cuneyt; Ucgul, Ahmet Yucel; Gocun, Pinar Uyar
Purpose To evaluate the potential toxicity of operation microscopes with halogen and light emitting diode (LED) light source on the rabbit eyes. Materials and methods Thirty-two eyes of 16 male New Zealand pigmented rabbits were involved in the study. The rabbits were divided into two groups according to the type of light source applied. Only one eye of each rabbit was exposed to illumination light, unexposed fellow eyes served as the control group. Experimental groups included group 1 exposed to halogen light for 2 h and evaluated 1 day and 1 week after the illumination, group 2 exposed to LED light for two hours and evaluated 1 day and 1 week after the illumination. On the first and seventh days after exposing the light, we evaluated the rabbit corneas using in vivo confocal microscopy (IVCM). At the end of the seventh day, the Hematoxylin-eosin staining and TUNEL staining were performed to investigate the presence of apoptosis in the retina and retina pigment epithelium. Results Early IVCM findings revealed corneal epithelial cell ovalization and indistinct intercellular borders in the halogen light group. We also observed more increase in the keratocyte density index (23.7% vs 14.1%, p = 0.001, respectively) and the Bowman reflectivity index (12.4% vs 4.1%, p = 0.001, respectively) at first day of the light exposure in halogen light group compared to LED light group. However, late IVCM indicated that these findings disappeared one week later. No apoptosis was observed in the corneal and retinal layers in early and late examination groups. Conclusion The present experimental study demonstrated that both halogen and LED lights, which were commonly used for microscopic eye surgery, had no sustained adverse effect on the cornea and retina of the rabbits; however, halogen light had a temporary adverse effect on corneal epithelium and stroma, which resolved within 1 week.
AtıfWoS2OpenAlex5İncele - MakaleAçık Erişim2021Urologists' Role and Attitude in the Systemic Treatment of Urologic Cancers
Madendere, Serdar; Deger, Muslim Dogan; Demirkiran, Engin Denizhan; Yildiz, Huseyin Alperen
Objective: The goal of this study was to investigate Turkish urologists' role and attitude toward the systemic treatment of urologic cancers. Materials and Methods: An 18-item survey was e-mailed to 2305 certified Turkish urologists. The survey included questions designed to evaluate urologists' knowledge of chemotherapy procedures and their ability to manage complications, as well as how many of them perform systemic therapies and believe urologists should perform these therapies for urologic cancers. Results: We evaluated 305 responses. Most urologists (89.6%) perform hormonotherapy for prostate cancers. Further, the majority refer patients to medical oncologists for chemotherapy. Moreover, 65.9%, 70.8%, and 72.1% of the urologists believe that only medical oncologists should deliver chemotherapy for prostate, bladder, and testicular cancers, respectively. Only 23.9% of urologists believe they are competent to perform chemotherapy, while 16.7% believe they are capable of dealing with chemotherapy complications. Conclusion: Turkish urologists have a lack of performance and interest in administering systemic therapies in urologic cancers. We want to emphasize that urology is more than just surgery. Urologists should be involved in all stages of cancer treatment.
AtıfWoS1OpenAlex1İncele - MakaleAçık Erişim2021Scopus SJRQ1Treating surgical site infection following posterior instrumentation with free-style deepithelialized propeller flap: A case report
Datli, Asli; Karasoy, Ismail; Zeynal, Mete
Surgical site infection is a challenging situation for all types of surgeons. Extensive debridement with or without implant removal can create soft tissue defects. A well-vascularized, adequate soft tissue is needed to cover the wound and to fill the dead space for proper healing. Herein, we describe our approach to a large posterior trunk defect with dead space and our solution to manage an intraoperative complication using a free-style deepithelialized propeller flap.
- Derleme MakaleAçık Erişim2021Scopus SJRQ4The New Disease of the Modern Age: What Is the Fear of Missing Out FOMO? A Review
Erdogan, Ali; Yilmaz, Yavuz; Hocaoglu, Cicek
Social networks have become a very important part of human life in recent years. This situation has led to new definitions such as the Fear of Missing Out (FOMO). FOMO can be defined as the concern that others can have a good experience when the person is absent and therefore the person wants to stay on social networks constantly to avoid missing anything. It is especially common in young people. Problematic internet use, psychosocial factors, social network use and anxiety are blamed in its etiology. Family conflicts, loneliness, depression, and low self-efficacy can be said as risk factors. People constantly want to spend time on social networks, daily life activities are blocked and the person's productivity decreases. It has no place in diagnostic classifications. For FOMO, the fear of missing out scale developed by Przybylski can be used. It is reported that FOMO has a significant positive relationship with nomophobia. There is no specific treatment method. There is a need for extensive research on FOMO.
AtıfWoS2OpenAlex3İncele - MakaleAçık Erişim2021The Effect of Rosa pimpinellifolia Extract on the Proliferation of Human Tumor Cells
Demir, Elif Ayazoglu; Demir, Selim; Türkmen, Nihal; Turan, Ibrahim
The aim of this study was to evaluate the antioxidant properties of R. pimpinellifolia and its cytotoxic effect against human colon (WiDr), liver (HepG2) and lung (A549) cancer cells compared with a normal fibroblast (BJ) cell line. The antioxidant properties of extract was determined using spectrophotometric methods, while the cytotoxic effect of extract was evaluated using MTT assay. The total phenolic content, total flavonoid content and reducing power values of extract were calculated as 16.4 +/- 0.4 mg gallic acid equivalent, 5.2 +/- 0.2 mg quercetin equivalent and 34.3 +/- 2.4 mg trolox equivalent per g sample, respectively. Although the extract exhibits selective cytotoxic effect on three cancer cell lines in a dose-dependent manner compared to BJ cells, the highest selectivity index value (2.7-fold) was obtained for the WiDr cell line. In conclusion, this is the first study to demonstrate the cytotoxic effect of R. pimpinellifolia on cancer cells. To demonstrate the molecular mechanism of this cytotoxic effect and to carry out in vivo studies may be a guide for future clinical studies.
AtıfWoS3OpenAlex5TR Dizin1İncele - MakaleAçık Erişim2021Evaluation of Cytotoxic Effect of Onosma armeniacum Extract on Various Cancer Cells
Demir, Selim; Ayazoglu Demir, Elif; Turan, Ibrahim; Özgen, Ufuk
The aim of this study was to investigate the antioxidant properties of the root extract of Onosma armeniacum and its cytotoxic effect against human liver (HepG2), lung (A549) and colon (WiDr) cancer cell lines compared with a normal fibroblast cell line. Antioxidant properties of the extract was determined using the colorimetric methods. The cytotoxic effect of the extract were investigated using MTT assay. The total phenolic content and reducing power values of extract were 26.1 +/- 0.4 mg gallic acid equivalent and 52.6 +/- 1.1 mg trolox equivalent per g sample, respectively. The extract exhibited selective cytotoxic effect in all studied cancer cell lines, especially HepG2 (3.6-fold). The results of this study reveal that O. armeniacum, which has been found to have acceptable antioxidant and cytotoxic effects, should be examined with more comprehensive studies.
AtıfWoS8OpenAlex12TR Dizin1İncele - MakaleAçık Erişim2021Men's Choice of Contraception Method
Ozcan, Handan; Yigitbas, Cagla; Karaca, Mucahit Talha
Objective: The aim of this study is to examine the contraception choices of men, aged between 18-60 and living in the center of a province in the Gumushane. Methods: The study is of a descriptive type. As a data collection form, an Individual Information Form consisting of a total of 32 questions was used. This form questions the demographic-physical-biological-social-health histories of the participants and their knowledge, attitudes, behaviors about contraception methods. Averages were given together with standard deviations. Results: 20.8 % of the participants are aged between 26-33. It was seen that 25.3% of the participants had knowledge about contraception methods and 64.7% did not use any methods. When the variables of the age and the marital status are approached in terms of having sufficient knowledge about contraception and still using contraception methods, there is a statistical significance between the variable of 'is the use of contraception methods harmful to health?' with the status of still using contraception methods. A statistical significance is also found between the variable of being sexually active with the status of having sufficient knowledge about contraception and still using contraception methods (p<0.05). Conclusion: In this study, It has been determined that men who had sufficient information about contraceptions had higher age and higher education levels, were sexually active and married. It has been seen that the age, the marital status, the perception of contraception as harmful to health, the status of being sexually active did not affect receiving any training about contraception.
- BildiriAçık Erişim2021Investigation of In-Vitro Properties of NiTi Alloy After Micro Arc Oxidation
Süküroglu, Suleyman; Totik, Yapr; Süküroglu, Ebru Emine; Küçükosman, Ridvan
As material science is integrated into medical science as in other fields, the variety, development and usage areas of biomaterials increase. One of the biomaterials in this variety is NiTi alloys. This study was focused on the coating of TiO2 layer by using the method of Micro Ark Oxidation with the aim of the improvement of surface and mechanical properties of Shapedmemory and bio material NiTi alloy. Structural properties of the coatings were analysed by of SEM and XRD. In vitro ability was investigated by soaking the coated NiTi samples in simulated body fluid (SBF) at temperature 37 degrees C for various time periods. After soaking, Ni+2 release was applied to the media where coated and uncoated shape-memory NiTi samples are available, and its control was made by means of ICP-MS device. The results also show that Toxic and carcinogenic effects of Ni+2 release is significantly reduced by the TiO2 coating. Thus, it is observed that the properties that limit the use of NiTi alloys has been substantially fixed by MAO coating. It was found that the bioactive properties of the TiO2 coated NiTi substrate increased by MAO method and at the end of the 72 hour, there was no statistically any cytotoxicity in cell viability compared to the NiTi substrate.
AtıfWoS3OpenAlex2İncele - MakaleYalnız künye2021Scopus SJRQ1Challenges of Setting up a Lower Extremity Reconstruction Practice in a Constrained Environment
Datli, Asli; Karasoy, Ismail; Genc, Yucel; Pilanci, Ozgur
Background Microsurgical lower extremity reconstruction remains challenging, especially when resources are limited such as lack of proper equipment, human resources, administrative support, and located in a remote area far from tertiary care. Nevertheless, reconstructive solutions are required, especially when in urgent trauma situations. In this article, we evaluate ways of overcoming challenges and issues that should be considered in a newly established unit by sharing our initial lower extremity reconstruction experience. Methods We report a local hospital's initial lower extremity reconstruction experience in February 2017 to January 2018. Through a total of seven patients, we tried to enhance the environment, instruments, nurses' contribution, and perspective of the peers and community in terms of factors related to the surgeon, hardware, environment, supporting faculty, reimbursement, and patients. Results Four patients underwent reconstruction with a freestyle propeller flap and three with an anterolateral thigh flap; in one case, a superficial circumflex iliac artery perforator flap was chosen to salvage partial flap necrosis. Increased experience of the surgeon, new equipment, continuing nurse/patient education, and collaborating with other departments allowed us to choose more challenging flaps and be more meticulous while decreasing the operation time and hospital stay. Conclusion To start a lower extremity reconstruction practice in a resource-poor environment, the surgeon needs to evaluate the relevant factors; moreover, he or she should continuously improve them until a working methodology is achieved. Despite all the challenges, the adaptations learned at this center can be applied to other local hospitals around the world to set up a lower extremity reconstruction practice and improve its outcomes.
AtıfWoS4OpenAlex4İncele - MakaleAçık Erişim2021Effect of precautionary and normalization steps on course of COVID-19 pandemic in Turkey
Bostan, Sedat; Agac, Gokhan; Sahinöz, Saime
Aim: The COVID-19 pandemic began in China and has now spread across the whole world, and many countries such as Turkey are still fighting against this pandemic. The aim of this study was to investigate the impact of precautionary and normalization steps taken by the Turkish government on the number of confirmed cases, current cases, and deaths due to the COVID-19 in Turkey. Materials and Methods: The study used exponential regression models to estimate the number of confirmed cases, deaths, and current cases. The study data were collected from the Turkish Ministry of Health, Turkish Ministry of Internal Affairs, and the national public broadcaster of Turkey. Results: The precautions taken during the COVID-19 pandemic have caused the exponentially increasing number of cases to be brought under control and to decrease exponentially. The normalization steps taken paused the exponential decrease in the number of cases and caused the number of cases to remain flat during the summer months and then rise again. If the normalization steps were not implemented and the precautions taken continued in the same way, it was calculated that the numbers of COVID-19 current cases would be reset on June 26, 2020. The total number of deaths would remain at 4423 and the total number of confirmed cases would be 150586. Discussion: As a result, the impact of precautionary and normalization steps on the course of the COVID-19 pandemic was examined. It has been observed that the impact of these steps on the pandemic is exponential. The results provide guidelines for health authorities and administrators to take necessary precautions.
AtıfWoS1OpenAlex2İncele - MakaleYalnız künye2021The first record of Lacinius dentiger (C. L. Koch, 1848) (Opiliones: Phalangiidae) in Turkey
Kurt, K.; Elverici, M.; Kunt, K. B.
The Lacinius dentiger (C.L. Koch, 1848) of the family Phalangiidae is recorded from Turkey for the first time. Its dorsal body view, chelicerae, and pedipalp are illustrated. Locality data of this species are also given.
- MakaleYalnız künye2021Scopus SJRQ3FEAR, ANXIETY, BURNOUT, AND INSOMNIA LEVELS OF HEALTHCARE WORKERS DURING COVID-19 PANDEMIC IN TURKEY
Yilmaz, Yavuz; Erdogan, Ali; Bahadir, Erdi
Background: This study aims to assess fear, anxiety, anxiety sensitivity, burnout, and insomnia of healthcare workers (HCWs) during novel coronavirus-2019 (COVID-19) outbreak and to identify their relation to sociodemographic and clinical characteristics. Subjects and methods: Totally 600 HCWs were included in this cross-sectional study. A Sociodemographic Data Form, Coronavirus Anxiety Scale (CAS), Fear of COVID-19 Scale (FCV-19S), Anxiety Sensitivity Index-3 (ASI-3), Maslach Burnout Inventory (MBI), and Insomnia Severity Index (ISI) were used. Results: Of participants, 364 were females and 236 were males with a mean age of 33.49 +/- 7.29 years. About 95.3% of HCWs had a fear of infecting their loved ones. Mean MBI and ISI scores were significantly higher among HCWs working in COVID-19 clinics and intensive care units (p=0.000; p=0.039). Mean CAS, FCV-19S, MBI, and ISI scores were significantly higher in women than men (p=0.000; p=0.000; p=0.027; p=0.005). Mean CAS and ISI scores were significantly higher among nurses (p=0.008; p=0.004), while mean ASI-3 of the other HCWs and MBI scores of physicians were significantly higher (p=0.009; p=0.000). Conclusion: The COVID-19 pandemic is a major health issue associated with psychiatric illnesses in HCW subgroups with distinct sociodemographic characteristics. It is of utmost importance to develop individualized preventive and therapeutic psychiatric services for HCWs.
AtıfWoS14İncele - MakaleAçık Erişim2021Diabetes Risk Assessment with Blood Parameters of The First Degree Relatives of Patients with Type-2 Diabetes Mellitus
Demirag, Hatice; Boyraz, Sakine
Objective: This study was conducted to evaluate the diabetes risk in first degree relatives of Type-2 diabetic patients who were not diagnosed with diabetes and test the validity of the Finnish Diabetes Risk Score (FINDRISK) in determining the risk of type-2 diabetes. Methods: First degree relatives of patients who were hospitalized in Izmir Katip Celebi University Ataturk Training and Research Hospital, who were not diagnosed with diabetes before, were included in this cross-sectional study. The sample of the research consisted of 200 people determined by power analysis. Data were collected by a structured question form and the FINRISK scale. Participants' height, weight, waist circumference were measured by the researcher, and venous fasting blood glucose (FBG) with Glycosylated Hemoglobin (HbA1c) were taken by the researcher. Results: The average age of the participants was 46.93 +/- 14.83 (18-86). It was determined that the vast majority of the individuals participating in the study were female (65%), 63% were married, 50.5% received high school or higher education, and 59% worked in an income-generating job. The findings was indicated that 41.5% of the participants were in the 'high-risk group' for type-2 diabetes according to the FINDRISK score scale. Sensitivity of FINDRISK score to FBG was 100% and specificity was 60%. Conclusion: As a result of findings in this study indicate that It was determined that the risk of DM was high in the first degree relatives of the patients hospitalized with Type-2 DM and the FINDRISK score scale was a good scale in predicting new asymptomatic Type 2 diabetes.
AtıfWoS1OpenAlex1TR Dizin2İncele - MakaleAçık Erişim2021Effects of Using Solar Water Heating System on Fuelwood Consumption in Forest Villages
Çakir, Gunay; Tonyali, Suleyman
Ain of study: In this study, the effects of the use of solar water heating system of forest villagers in Gumushane were investigated. Material and methods: For this purpose, random selected by 70 forest village households were examined and the results were analyzed by One Sample T-Test. Within the scope of the research, face-to-face surveys were conducted with the families with the villagers who were determined with information provided by Department of Forest-Village Relations. The villagers were chosen among those who had used this solar energy heating system for at least 5 years. The data in the questionnaires were transferred to digital media and it was tried to determine how the forest villagers were affected by solar water heating systems. Main results: As a result, after the use of solar water heating systems; the consumption of firewood for heating has not changed. The consumption of wood used for cooking and the consumption of wood used for hot water has also decreased. Highlights: Thanks to this solar water heating system, carbon accumulation in forests has increased and a positive contribution has been made to climate change.
- MakaleYalnız künye2021The Effect of Foreign Trade By Technology Intensity on Economic Growth: The Case of Turkey
Akyol, Mehmet; Mete, Emrullah
In today's international trade conditions, countries need to complete their technological developments in order to increase their competitiveness and economic growth. High technology exports are very important, especially for countries aiming for export-oriented growth. In this study, the effect of export and import performance according to technology intensity on the economic growth were analyzed for Turkey. In this context, data for the period 2002-2018 were analyzed with the ARDL boundary test approach. According to the analysis results, it was determined that low, low-medium, medium-advanced and advanced technology exports and imports and economic growth are co-integrated.
AtıfTR Dizin4İncele - MakaleAçık Erişim2021Scopus SJRQ3Erectile dysfunction treatment with Phosphodiesterase-5 Inhibitors: Google trends analysis of last 10 years and COVID-19 pandemic
Deger, Muslim Dogan; Madendere, Serdar
Objectives: We aimed to analyze the trend change of the most popular Phosphodiesterase-5 Inhibitors (PDE5i) over time and geography by using Google Trends (GT) data in 10 years period and COVID-19 pandemic. Materials and methods: GT is able to generate a line-graph, showing how interest has increased or decreased over a period within specific territories. The search values for specific terms are indexed as relative search volume (RSV), which is presented on a scale from 0-100. Avarage annual percentage change (AAPC) and RSV were analyzed to evaluate gain or loss of interest in trends. Search terms were generated for Food and Drug Administration (FDA)-approved PDE5i; tadalafil, sildenafil, vardenafil, avanafil, and their most-used brand names. The data was within worldwide from 1 January 2010, to 31 December 2020, using the global query category. Results: The overall interest in PDE5i has doubled. Sildenafil has become the most trend PDE5i of today with a regular increase (AAPC: 0.016, p < 0.01). Although the search trend of tadalafil remained almost constant until 2014, the rate of increase in the last 6 years raised and tadalafil has become the 2nd most popular PDE5i recently (AAPC: 0.007, p < 0.01). For vardenafil there has been a decreased interest (AAPC: -0.009, p < 0.01). There is no significant change in avanafil trend (AAPC: 0.000, p: 0.5). All PDE5i interest on GT decreased notably from February to June 2020. But after June, search trends reached the level before the COVID-19 period in a month. Conclusions: These findings show us, with its increasing prevalence, erectile dysfunction (ED) has become a major public health problem. People from different geographies search the Internet for ED treatment options. Patients should be informed that ED may be the first sign of many comorbid diseases, and patients with ED should be referred to a health institution for diagnosis and treatment.
AtıfWoS11OpenAlex13İncele - MakaleAçık Erişim2021Relationship between androgen levels and neutrophil/lymphocyte ratio in patients diagnosed with hirsutism
Sayilan, Samet; Mert, Meral; Kulakac, Nursen
Aim: Hirsutism is a disease involving increased terminal hair growth in women with a male-type distribution pattern in androgen-sensitive areas such as the chin, upper lip, chest, abdomen, back, and thighs. Our review of the available literature revealed no previous studies concerning the role of the peripheral blood neutrophil/lymphocyte ratio (NLR), an easily calculated and noninvasive marker, in hirsutism. The purpose of this research was to determine the relationship between androgen levels and NLR in female patients diagnosed with hirsutism. Material and Methods: The files of 392 patients presenting to the Bakirkoy Dr. Sadi Konuk Education and Research Hospital due to hirsutism between 2018 and 2020 were included in this cross-sectional, retrospective study. Patients' hirsutism and menstrual cycles, age at menarche, number of pregnancies in the case of married women, number of living children, and history of infertility were investigated. Hyperandrogenemia findings, such as hair loss and acne, were also recorded. Patients' biochemical and complete blood count parameters were evaluated. Results: The mean age of the participants was 26.27 +/- 6.37 years (min-max: 16-48), and their androgen levels were statistically significantly associated with high-density lipoprotein, hemoglobin, hematocrit, 17-hydroxyprogesterone, and HbA1c levels (p<0.05). However, no significant relationship was found between patients' androgen levels and NLR values (p>0.05). Discussion: No significant relationship was determined in this study between androgen levels and NLR values in women diagnosed with hirsutism. Due to the limited numbers of previous similar studies, further research with larger patient numbers is now needed.
AtıfWoS1İncele - MakaleAçık Erişim2021Scopus SJRQ2Correlation of bilateral and ipsilateral strength ratios with balance in female taekwondo athletes
Yilmaz, Ali Kerim; Yilmaz, Coskun; Karaduman, Emre; Mayda, Muhammet Hakan; Erail, Serhat; Bostanci, Ozgur; Kabadayi, Menderes
This study aimed to analyze preferred leg (PLs) and non-preferred leg (NPLs) isokinetic knee strength, lateral asymmetry ratios and to examine their correlation with static balance. Sixteen female taekwondo (TKD) athletes voluntarily participated in the study. Knee isokinetic extension (Ex) and flexion (Flx) strength were measured in concentric / concentric (Con / Con) contractions at angular velocities of 60 degrees/s, 180 degrees/s, and 240 degrees/s. Ipsilateral hamstring / quadriceps (H/Q) and bilateral (H/H and Q/Q) ratios were calculated. Static balances were determined by taking the center of body pressure in X (COPX) and Y (COPY) axis. Paired sample t-test and Pearson correlation tests were used in statistical analysis. When the isokinetic knee strength was examined, it was found that 60 degrees/s angular velocity parameter was significantly different in Flx phase while 180 degrees/s and 240 degrees/s angular velocities were found to be significantly different in Ex phase in favor of PLs. There was no significance in bilateral and ipsilateral strength ratios of all angular velocities. There was a significant correlation between 240 degrees/s HQ and COPX in terms of ipsilateral asymmetry ratios whereas a significant correlation was found between 60 degrees/s HH and COPX in terms of bilateral asymmetry ratios. It was found that there were differences in strength between PL and NPLs, but no asymmetry was observed. There was no high level of correlation between lateral asymmetry ratios and balance in female TKD practitioners.
AtıfWoS5OpenAlex9İncele - MakaleAçık Erişim2021Scopus SJRQ1Upper extremity arterial thromboembolism in a patient with severe COVID-19 pneumonia: A case report
Bilge, Aysegul; Karasoy, Ismail; Neziroglu, Elif; Güner, Yesim
Although novel coronavirus-2019 (COVID-19) primarily affects the respiratory system, it can affect multiple organ systems, leading to serious complications, such as acute respiratory distress syndrome (ARDS) and multiple organ failure. Nearly 20 to 55% of patients with COVID-19 experience coagulation disorders that cause high mortality in line with the severity of the clinical picture. Thromboembolism can be observed in both venous and arterial systems. The vast majority of thromboembolic events are associated with the venous system and are often observed as pulmonary embolism. Arterial thromboembolisms often involve the arteries in the lower extremities, followed by those in the upper extremities. Herein, we report a rare case of COVID-19 pneumonia whose left arm was amputated at the forearm level after arterial thromboembolism in the left upper extremity. This case report is valuable, as it is the first reported case of upper extremity arterial thromboembolism in Turkey, as well as the only case in the literature in which the patient underwent four surgical interventions and is still alive.
AtıfWoS2OpenAlex3İncele - MakaleAçık Erişim2021Investigation of the Cytotoxic Effect of Ethyl Pyruvate on Various Cancer Cell Lines
Ayazoglu Demir, Elif; Demir, Selim; Turan, Ibrahim
Ethyl pyruvate (EP) is a simple aliphatic ester derived from pyruvic acid which is an endogenous metabolite. Although various studies have investigated the antioxidant and anti-inflammatory properties of EP, there has been only limited research into the cytotoxic effect of EP on cancer cells. The aim of this study was to determine the cytotoxic effects of EP on cells representing common cancer types. EP was purchased commercially and intermediate stock solutions were prepared with phosphate buffer saline. The cytotoxic effect of EP on human melanoma (VMM917), cervix (HeLa), breast (MCF-7), lung (A549), liver (HepG2), colon (WiDr) cancer and normal fibroblast (BJ) cells was determined using the MTT assay. Cisplatin was used as a positive control in cytotoxicity experiments. The results showed that EP exhibits selective cytotoxic effect on VMM917 (10.1-fold) and HeLa (3.04-fold) cells compared to BJ cells. This study shows for the first time that EP has a highly selective cytotoxic effect, especially on melanoma and cervix cancer cells. The mechanism of this effect needs to be elucidated by more extensive studies.
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