Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Kulakaç, Nurşen(10)
- Çelik, Orkun(8)
- Ashyralyyev, Charyyar(7)
- Keyifli, Nazlı(7)
- Ashyralyev, A.(6)
- Kayikcioglu, Temel(6)
- Menevseoglu, Ahmed(6)
- Araz, Onur(5)
- Ashyralyyev, C.(5)
- Demirbağ, Orkun(5)
- Koç, Pinar(5)
- Turan, Ibrahim(5)
- Ünlü, Ramazan(5)
- Ürkek, Bayram(5)
- Akar, Zeynep(4)
- Akyol, Hikmet(4)
- Akyol, Mehmet(4)
- Aydınçakır, Emre(4)
- Bilgilioglu, Burhan Baha(4)
- Demir Doğan, Melike(4)
- Demir, Selim(4)
- Kankal, Murat(4)
- Kurnaz, Muammer(4)
- Melek, Mesut(4)
- Pala, Fahrettin(4)
- Sancar Özkök, Canan(4)
- Taş, Ahmet(4)
- Ulutaşdemir, Nilgün(4)
- Uzun, Sevda(4)
- Acet, Tuba(3)
- Akay, K.U.(3)
- Aydin Sayilan, Aylin(3)
- Aydın Sayılan, Aylin(3)
- Barut, Abdulkadir(3)
- Basoglu, Mustafa Engin(3)
- Cakalli, H.(3)
- Canak, I.(3)
- Cengiz, Ekrem(3)
- Cengiz, Emre(3)
- Cengiz, Sevil(3)
Yayınlar
- Derleme MakaleAçık Erişim2021The Large Hadron-Electron Collider at the HL-LHC
Agostini, P.; Aksakal, H.; Alekhin, S.; Allport, P. P.; Andari, N.; Andre, K. D. J.; Angal-Kalinin, D.; Antusch, S.; Aperio Bella, L.; Apolinario, L.
The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton-nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron-hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies.
- MakaleAçık Erişim2021LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kinkor (Ferulago stellata)
Kiziltas, Hatice; Bingol, Zeynebe; Gören, Ahmet Ceyhan; Kose, Leyla Polat; Durmaz, Lokman; Topal, Fevzi; Alwasel, Saleh H.; Gulcin, Ilhami
Kinkor (Ferulago stellata) is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this medicinal plant. In this study, the phytochemical composition; some metabolic enzyme inhibition; and antidiabetic, anticholinergic, and antioxidant activities of this plant were assessed. In order to evaluate the antioxidant activity of evaporated ethanolic extract (EEFS) and lyophilized water extract (WEFS) of kinkor (Ferulago stellata), some putative antioxidant methods such as DPPHGreek ano teleia scavenging activity, ABTS(center dot+) scavenging activity, ferric ions (Fe3+) reduction method, cupric ions (Cu2+) reducing capacity, and ferrous ions (Fe2+)-binding activities were separately performed. Furthermore, ascorbic acid, BHT, and alpha-tocopherol were used as the standard compounds. Additionally, the main phenolic compounds that are responsible for antioxidant abilities of ethanol and water extracts of kinkor (Ferulago stellata) were determined by liquid chromatography-high-resolution mass spectrometry (LC-HRMS). Ethanol and water extracts of kinkor (Ferulago stellata) demonstrated effective antioxidant abilities when compared to standards. Moreover, ethanol extract of kinkor (Ferulago stellata) demonstrated IC50 values of 1.772 mu g/mL against acetylcholinesterase (AChE), 33.56 +/- 2.96 mu g/mL against alpha-glycosidase, and 0.639 mu g/mL against alpha-amylase enzyme respectively.
- MakaleAçık Erişim2021Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS
Bingol, Zeynebe; Kiziltas, Hatice; Gören, Ahmet C.; Kose, Leyla Polat; Topal, Meryem; Durmaz, Lokman; Alwasel, Saleh H.; Gulcin, Ilhami
In order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed (Convulvulus betonicifolia Mill. Subs), some putative antioxidant methods such as DPPH. scavenging activity, ABTS(center dot)(-) scavenging effect, ferric ions (Fe3+) reduction method, cupric ions (Cu2+) reducing capacity, and ferrous ions (Fe2+) binding activities were separately performed. Also, ascorbic acid, alpha-tocopherol and BHT were used as the standard compounds. Additionally, some phenolic compounds that responsible for antioxidant abilities of EESB and WESB were screened by liquid chromatography-high resolution mass spectrometry (LC-HRMS). At the same concentration, EESB and WESB demonstrated effective antioxidant abilities when compared to standards. In addition, EESB demonstrated IC50 values of 1.946 mu g/mL against acetylcholinesterase (AChE), 0.815 mu g/mL against alpha-glycosidase and 0.675 mu g/mL against alpha-amylase enzymes.
- MakaleYalnız künye2021The effect of chewing gum on dry mouth, interdialytic weight gain, and intradialytic symptoms: A prospective, randomized controlled trial
Ozen, Nurten; Aydin Sayilan, Aylin; Mut, Dilek; Sayilan, Samet; Avcioglu, Zeynep; Kulakac, Nursen; Ecder, Tevfik; Akyolcu, Neriman
Introduction The major salivary glands can be stimulated by chewing gum to increase saliva flow and decrease xerostomia. The aim of this study was to investigate the effect of chewing gum on dry mouth, interdialytic weight gain, and intradialytic symptoms in hemodialysis (HD) patients. Methods This prospective randomized controlled single-blind study was conducted with patients who had been treated for at least 6 months with sessions 3 days a week for 4 hours at two HD units. Patients were randomly allocated to chewing gum group or the control group. In the chewing gum group, gum was chewed for 10 minutes six times a day, and when the patients felt mouth dryness or were thirsty. In the nonchewing gum group, gum was not chewed. The patients were followed-up for 3 months. A total of three saliva samples were taken before starting treatment at the first, 12th, and 36th HD session. Data were collected with the Visual Analogue Scale (VAS), Hemodialysis Patients Fluid Control Scale, Dialysis Symptom Index, and Hospital Anxiety and Depression Scale at baseline, week 4, week 8, and week 12. Findings The study was completed with a total of 44 patients consisting of 22 patients in the each group. The second and third month VAS values (xerostomia) of the patients in the chewing gum groups were statistically significantly lower than those in the control group (P= 0.014,P < 0.001, respectively). The third month salivary flow rate in the chewing gum group was higher than the values in the control group patients (P < 0.001). Discussion It is anticipated that this study will raise nurses' awareness of dry mouth and encourage future studies on interventions to increase the salivary flow rate to prevent or treat dry mouth.
- MakaleAçık Erişim2021Non-Invasive Monitoring of Ethanol and Methanol Levels in Grape-Derived Pisco Distillate by Vibrational Spectroscopy
Menevseoglu, Ahmed; Aykas, Didem P.; Hatta-Sakoda, Beatriz; Toledo-Herrera, Victor Hugo; Rodriguez-Saona, Luis E.
Handheld Raman and portable FT-IR spectroscopy devices were evaluated for fast and non-invasive determination of methanol and ethanol levels in Peruvian Pisco. Commercial Peruvian Pisco (n = 171) samples were kindly provided by the UNALM Alliance for Research in Alcohol and its Derivatives (Lima, Peru) and supplemented by purchases at grocery and online stores. Pisco spectra were collected on handheld Raman spectrometers equipped with either a 1064 nm or a 785 nm excitation laser and a portable infrared unit operating in transmission mode. The alcohol levels were determined by GC-MS. Calibration models used partial least-squares regression (PLSR) to develop prediction algorithms. GC-MS data revealed that 10% of Pisco samples had ethanol levels lower than 38%, indicating possible water dilution. Methanol levels ranged from 10 to 130 mg/100 mL, well below the maximum levels allowed for fruit brandies. Handheld Raman equipped with a 1064 nm excitation laser gave the best results for determining ethanol (SEP = 1.2%; RPre = 0.95) and methanol (SEP = 1.8 mg/100 mL; RPre = 0.93). Randomly selected Pisco samples were spiked with methanol (75 to 2800 mg/100 mL), and their Raman spectra were collected through their genuine commercial bottles. The prediction models gave an excellent performance (SEP = 98 mg/100 mL; RPre = 0.97), allowing for the non-destructive and non-contact determination of methanol and ethanol concentrations without opening the bottles.
- MakaleYalnız künye2021Non-targeted approach to detect green pea and peanut adulteration in pistachio by using portable FT-IR, and UV-Vis spectroscopy
Menevseoglu, Ahmed; Aykas, Didem Peren; Adal, Eda
Pistachio is one of the most expensive nuts with having high economic importance in Turkey. It has become more prone to adulteration because of its high commodity value. Peanut with color additives and green pea are generally used to adulterate ground pistachio. Vibrational spectroscopy is a potential technique to detect adulterations in pistachio. The objective of this study was to generate a non-targeted method for portable FT-IR and UV-Vis spectrometers to authenticate pistachio and detect green pea and peanut adulterations. Pistachio granules were adulterated with green pea and peanut at different concentrations (5 to 40% w/w). Spectra were collected by a portable FT-IR spectrometer and by a conventional UV-Vis spectrometer and analyzed by Soft Independent Modeling of Class Analogy (SIMCA) to generate classification algorithms to authenticate pistachio, and Partial Least Square Regression (PLSR) to predict the concentrations of adulterants. SIMCA showed very distinct clusters for pure samples. Moreover, adulterated pistachio samples were discriminated by SIMCA even in low levels of adulteration (5%). Portable FTIR showed excellent performance (r(val) > 0.93) of predicting the adulterant levels with a standard error of prediction (SEP) 0.66% and 0.80% for green pea and peanut, respectively. Similarly, UV-VIS predicted (r(val) > 0.93) the adulterant levels with SEP 0.58% and 0.14% for green pea and peanut, respectively. The results supported that portable FT-IR, and UV-Vis units present great potential for real-time surveillance of green pea and peanut adulteration in pistachio.
- MakaleAçık Erişim2021Role of the Health System in Combating Covid-19: Cross-Section Analysis and Artificial Neural Network Simulation for 124 Country Cases
Bayraktar, Yuksel; Özyilmaz, Ayfer; Toprak, Metin; Isik, Esme; Büyükakin, Figen; Olgun, Mehmet Firat
In the fight against Covid-19, developed countries and developing countries diverge in success. This drew attention to the discussion of how different health systems and different levels of health spending are effective in combating Covid-19. In this study, the role of the health system in the fight against Covid-19 is discussed. In this context, the number of hospital beds, the number of doctors, life expectancy at 60, universal health service and the share of health expenditures in GDP were used as health indicators. In the study, firstly 2020 data was estimated by using the Artificial Neural Networks simulation method and this year was used in the analysis. The model, with the data of 124 countries, was estimated using the cross-sectional OLS regression method. The estimation results show that the number of hospital beds, number of doctors and life expectancy at the age of 60 have statistically significant and positive effects on the ratio of Covid-19 recovered/cases. Universal health service and share of health expenditures in GDP are not significant statistically on the cases and recovered. Hospital bed capacity is the most effective variable on the recovered/case ratio.
- MakaleAçık Erişim2021Adipokine, gut and thyroid hormone responses to probiotic application in chukar partridges (Alectoris chukar) exposed to heat stress
Bayraktar, Bulent; Tekce, Emre; Kaya, Hacer; Gürbüz, Ahmet Burak; Dirican, Ebubekir; Korkmaz, Serol; Atalay, Banu; Ülker, Ufuk
The aim of this study was to investigate the effect of Lactobacillus reuteri E81 (LRE) probiotic supplementation on heat stress responses in chukar partridges (Alectoris chukar). The birds were divided into two groups, one of which was exposed to heat stress (HS). Within each group, four subgroups, each including 64 birds, were created for the three treatment doses (200, 400 or 600 mg/kg) of LRE and the control. The experiment was started with day-old birds, kept at a temperature of 25 degrees C or 37 degrees C. After a 7-day adjustment period, the LRE supplementation lasted for 35 days. The levels of different adipokines, including visfatin (VF), adiponectin (ADP), chemerin (CHEM), as well as the concentration of plasma citrulline (CIT) and the levels of thyroid hormones (T3 and T4) and thyroid-stimulating hormone (TSH) in the blood were measured at 21 and 42 days of age. A significant correlation (P < 0.01) was found between LRE supplementation and the decrease in serum VF, ADP, CIT, T3 and T4 levels in partridges exposed to HS. On the other hand, no significant relationship was found between LRE supplementation and the serum CHEM and TSH levels (P > 0.05). We concluded that the addition of 600 mg/kg LRE is beneficial in preventing intestinal damage and inflammation provoked by HS.