Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(87)
- Merdan, Mehmet(70)
- Duran, Celal(56)
- Baltaci, Cemalettin(52)
- Kulakaç, Nurşen(51)
- Ozdes, Duygu(51)
- Kaygusuz, Abdullah(47)
- Öztürk, Serkan(42)
- Demir, Selim(40)
- Karsli, Orhan(37)
- Turan, Ibrahim(37)
- Dokuz, Abdurrahman(36)
- Gücer, Mehmet Ali(36)
- Sipahi, Ferkan(36)
- Araz, Onur(35)
- Kandemir, Raif(31)
- Vural, Alaaddin(31)
- Topal, Fevzi(30)
- Kurt, Kemal(29)
- Ürkek, Bayram(29)
- Maden, Nafiz(28)
- Acet, Tuba(27)
- Alemdag, Selcuk(26)
- Arslan, Mehmet(26)
- Ayaydin, Hasan(26)
- Akaryali, Enver(25)
- Aydin, Faruk(25)
- Baltacı, Cemalettin(25)
- Yücel, Cem(25)
- Akar, Zeynep(24)
- Barut, Abdulkadir(24)
- Ozturk, Samet(24)
- Pala, Fahrettin(24)
- Peker, Iskender(24)
- Topal, Meryem(24)
- Yildiz, Salih(24)
- Öz, Mehmet(24)
- Aliyazicioglu, Yuksel(23)
- Bostan, Sedat(23)
- Kankal, Murat(23)
Yayınlar
- MakaleAçık Erişim2017Scopus SJRQ2Effect of brewing conditions on antioxidant properties of rosehip tea beverage: study by response surface methodology
İlyasoğlu, Huri; Arpa, Tuba Eda
The aim of this study was to investigate the effects of brewing conditions (infusion time and temperature) on the antioxidant properties of rosehip tea beverage. The ascorbic acid content, total phenolic content (TPC), and ferric reducing antioxidant power (FRAP) of rosehip tea beverage were analysed. A two-factor and three-level central composite design was applied to evaluate the effects of the variables on the responses. The best quadratic models were obtained for all responses. The generated models were validated under the optimal conditions. At the optimal conditions, the rosehip tea beverage had 3.15 mg 100 mL−1 of ascorbic acid, 61.44 mg 100 mL−1 of TPC, and 2591 µmol of FRAP. The best brewing conditions for the rosehip tea beverage were found to be an infusion time of 6–8 min at temperatures of 84–86 °C.
AtıfScopus31WoS23OpenAlex33
İncele - MakaleAçık Erişim2017Scopus SJRQ4The effect of sintering in different atmospheres on superconductivity parameters of YBCO
Başoǧlu, Mehmet
YBa2Cu3O7 (Y123) is a superconductor material discovered in 1987 and its transition temperature is above the liquid nitrogen temperature. It is known that superconductor samples produced by the solid-state reaction route are very often sintered in air atmosphere. However, in the presented work, Y123 was prepared by the same technique using a sintering ambient composed of a mixture of oxygen and argon gases for the first time. Critical current densities of the samples were calculated using results of magnetization measurements. It was obtained from magnetization analysis that all the samples exhibited superconductor character. It was also observed that the sample sintered in the 50% oxygen and 50% argon atmosphere showed the highest critical current density.
AtıfOpenAlex1
İncele - MakaleAçık Erişim2017Scopus SJRQ1A new colorimetric DPPH• scavenging activity method with no need for a spectrophotometer applied on synthetic and natural antioxidants and medicinal herbs
Akar, Zeynep; Küçük, Murat; Doğan, Hacer
2,2-Diphenyl-1-picrylhydrazyl (DPPH•) radical scavenging, the most commonly used antioxidant method with more than seventeen thousand articles cited, is very practical; however, as with most assays, it has the major disadvantage of dependence on a spectrophotometer. To overcome this drawback, the colorimetric determination of the antioxidant activity using a scanner and freely available Image J software was developed. In this new method, the mixtures of solutions of DPPH• and standard antioxidants or extracts of common medicinal herbs were dropped onto TLC plates, after an incubation period. The spot images were evaluated with Image J software to determine CSC50 values, the sample concentrations providing 50% colour reduction, which were very similar with the SC50 values obtained with spectrophotometric method. The advantages of the new method are the use of lower amounts of reagents and solvents, no need for costly spectrophotometers, and thus significantly lowered costs, and convenient implementation in any environment and situation.
AtıfScopus188WoS143OpenAlex169İncele - MakaleYalnız künye2017Scopus SJRQ1An injectable alginate-based hydrogel for microfluidic applications
Akay, Seref; Heils, Rene; Trieu, Hoc Khiem; Smirnova, Irina; Yesil-Celiktas, Ozlem
The objective of this study was to develop an injectable alginate based formulation for immobilizing enzymes into microfluidic systems. The gelation was induced upon lowering the pH by addition of D-glucono-δ-lactone (GDL) and release of Ca+ ions from solid CaCO3. The effects of GDL concentration on enzymatic activity and gelation time were investigated. The results indicated that increasing the GDL concentration increased both surface area and enzymatic activity. Also, chitosan was added to the formulation at different ratios to enhance the stability of enzyme during immobilization. For microfluidic application, 100 μl spiral coil single channel microchip was fabricated and alginate GDL mixture containing β-glucosidase was injected to the microchannel prior to gelation. Enzymatic conversion was performed by pumping substrate (pNPG) through the microchannel. The results indicated that the entire substrate was converted continuously during 24 h without any leakage or deactivation of immobilized enzyme.
AtıfScopus42WoS34OpenAlex38İncele - MakaleYalnız künye2017Scopus SJRQ1An Investigation of the Seismic Behaviour of an Ancient Masonry Bastion Using Non-Destructive and Numerical Methods
Altunisik, A.C.; Adanur, S.; Genc, A.F.; Gunaydin, M.; Okur, F.Y.
Determining the structural behavior of masonry structures is a challenge due to their lack of homogeneity. The seismic behavior of masonry structures is especially complex. The aim of this study was to examine the structural behavior of Zağanos Bastion using both experimental and numerical methods. The Operational Modal Analysis technique, including the Enhanced Frequency Domain Decomposition Method, and the Stochastic Subspace Identification Method were used to illustrate experimentally the dynamic characteristic of the bastion. A finite element model was developed using ANSYS software in order that the dynamic characteristics of the bastion, including natural frequencies and mode shapes, could be calculated numerically. Seismic analysis was carried out using the 1999 Kocaeli earthquake ground motion record to determine the linear and nonlinear seismic behavior of the bastion. The Turkish Earthquake Code and its general technical specifications were used to evaluate the seismic results. The results show that the maximum and minimum principal stresses exerted on the masonry components exceeded the code requirements at some points, but in general the requirements for the stresses were satisfied.
AtıfScopus22WoS22OpenAlex19İncele - MakaleAçık Erişim2017Scopus SJRQ2Reaction of 9-oxabicyclo[4.2.1]non-7-ene-1-ol with tetrazine: An unusually facile intramolecular rearrangement
Kaya, Afşin A.; Salamci, Emine; Menzek, Abdullah; Erdem, Safiye S.; Şahin, Ertan; Ecer, Kadriye
Reaction of (1S*,7R*)-9-oxabicyclo[4.2.1]non-7-en-1-ol (5) with dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate (6) produced (2R*,4R*)-dimethyl 4-(7-oxooxepan-2-yl)-1,4-dihydropyridazine-3,6-dicarboxylate (11) in a one-pot reaction involving cycloaddition at ambient conditions. The structure of the rearrangement product 11 was determined by X-ray crystallographic analysis. Its formation was discussed based on experimental studies and density functional theory calculations. The driving force of this unusually facile reaction was the stability of the caprolactone product 11 and the extremely exorgenic loss of N2. Structural factors facilitating this rearrangement were also explored employing PCM//M06-2X/6-31G(d, p) calculations.
AtıfScopus22WoS17OpenAlex22İncele - MakaleYalnız künye2017Scopus SJRQ1An on-line HPLC system for detection of antioxidant compounds in some plant extracts by comparing three different methods
Arslan Burnaz, Nesibe; Küçük, Murat; Akar, Zeynep
Echinacea (Echinacea purpurea), green tea (Camellia sinensis) and yaylacayi (Thymus praecox OPIZ subsp. grossheimii (Ronniger) Jalas) are herbs used in traditional medicine because of their beneficial health effects. A high performance liquid chromatography (HPLC) post-column method was developed by coupling HPLC with on-line antioxidant assays using diode array (DAD) and ultraviolet (UV) detectors. Thus antioxidant compounds and fifteen phenolic standards were detected in echinacea, green tea and yaylacayi methanol extracts simultaneously. Later on, the developed on-line HPLC coupled system was used to compare three different antioxidant methods, ABTS [2,2′-Azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)], DPPH (2,2-diphenyl-1-picrylhydrazyl and FRAP (Ferric reducing antioxidant power). Eight compounds with antioxidant activity were identified as gallic acid, protocatechuic aldehyde, p-OH benzoic acid, chlorogenic acid, caffeic acid, vanillin, ferulic acid, and rosmarinic acid. For validation purposes, LOD (limit of detection) (0.36–14.68 μg/mL) and LOQ (limit of quantification) (1.35–48.92 μg/mL) values were calculated for six standards. The results showed that while the post-column ABTS and FRAP assays were repeatable, sensitive and supportive of each other, the post-column DPPH assay did not provide reliable results. Also due to the base-line noise and drifts in post-column DPPH assay, identification and quantitation of analytes could not be done accurately.
AtıfScopus46WoS42OpenAlex52İncele - MakaleAçık Erişim2017Nutmeg Intoxication Associated with Consumption as a Stupefacient
Günaydin, Mucahit; Tatli, Ozgur; Altuntas, Gurkan; Uslu, Zakire; Özsahin, Faruk; Beslioglu, Necla
Introduction: Nutmeg is the dried seed of an evergreen aromatic tree from the plant family Myristicaceae. It is widely used in traditional medicine. Although misuse is rare, it needs to be understood that this plant, widely used as a spice in various parts of the world, can be misused and can result in emergency presentation due to intoxication. Case Report: We describe a case of intoxication in a 22-year-old male student after he mixed nutmeg with fruit juice and drank it. Neurological symptoms and anticholinergic signs were present during presentation. Conclusion: Nutmeg intoxication must be one of the possibilities considered at differential diagnosis in patients presenting to the emergency department with findings of anticholinergic intoxication.
- MakaleAçık Erişim2017Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke
Karaca, Yunus; Tatli, Ozgur; Eryigit, Umut; Aksüt, Nurhak; Sahin, Aynur; Mentese, Ahmet; Altay, Diler Us; Beslioglu, Necla; Karatas, Mevlut; Örem, Asim
Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it. This study aimed to investigate the diagnostic value of serum yclophilin A levels in our study group who presented to the emergency department with symptoms of acute ischemic stroke. Materials and Methods: In total, 114 patients diagnosed with acute ischemic stroke between October 2013 and October 2014 and a control group of 66 healthy volunteers were included. Cyclophilin A levels in the patient and control groups were compared. Results: The median cyclophilin A levels in the patient and control groups measured at the time of presentation were 13.47 (11.97-17.92) ng/mL and 11.54 (8.48-16.22) ng/mL, respectively. These levels were significantly higher in the patient group than in the control group (p<0.05). Conclusion: Plasma cyclophilin A levels were significantly higher in the patient group than in the control group.
- MakaleYalnız künye2017Scopus SJRQ3Carbonic anhydrase I and II autoantibodies in Behcet's disease
Mentese, A.; Alver, A.; Demir, S.; Sumer, A.; Yaman S, Ozer; Karkucak, M.; Capkin A, Aydin; Us, Altay D.; Turan, I
Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a metalloenzyme which is widely distributed in the living world, and it is essential for the regulation of acid-base balance. Anti-CA antibodies have been reported in many disorders, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, endometriosis, idiopathic chronic pancreatitis, type 1 diabetes and Graves' disease. The goal of this study was to investigate CA I and II autoantibodies in BD. Methods: 35 patients with BD and 29 healthy controls were included in the study and CA I and II autoantibody levels were investigated by ELISA. Results: The CA I and II autoantibody levels of BD group were significantly higher than the healthy group (p= 0.013, p= 0.0001, respectively). A cut-off value of 0.250 absorbance unit (ABSU) for anti-CA I was associated with 34% sensitivity and 100% specificity and a cut-off value of 0.171 ABSU for anti-CA II was associated with 54% sensitivity and 100% specificity for predicting BD. Conclusion: The CA I and II autoantibody levels in pa-tients with BD were found higher compared to control group and the results suggest that CA I and II autoantibodies may be involved in the pathogenesis of BD
AtıfScopus10WoS9İncele - MakaleYalnız künye2017Scopus SJRQ1Petrogenesis of ultramafic rocks from the eastern Orhaneli ophiolite, NW Turkey: Hints on the initiation and evolution of melt-peridotite interaction processes within a heterogeneously depleted mantle section
Uysal, Ibrahim; Dokuz, Abdurrahman; Kapsiotis, Argyrios; Saka, Samet; Karsli, Orhan; Kaliwoda, Melanie; Mueller, Dirk
The eastern Orhaneli ophiolite in NW Anatolia (Turkey) consists of voluminous dunite and minor harzburgite intruded by clinopyroxenite veins. Harzburgite contains spinel of low Cr# [100 x Cr/(Cr + Al) = 40-45] and diopside of low Al2O3 and TiO2 contents, whereas dunite contains spinel of higher Cr# (62-82) and diopside (blebs) (even more) depleted in Al2O3 and TiO2 (than harzburgite). The concentrations of Heavy Rare Earth Elements (HREE) in harzburgite are consistent with derivation of this type of peridotite from 19% dry melting of a fertile mantle protolith at a MOR regime. Dunites have lower concentrations of HREE than harzburgite implying that dunites were generated by higher degrees (> 30%) of (cumulative) melting of the same protolith. Furthermore, the characteristic U-shapes of the chondrite-normalized REE-patterns of dunites indicate the involvement of hydrous melt-peridotite interaction processes in their genesis. Nevertheless, a set of mosaic-in texture dunite samples contain olivine that has lower Fo# [100 x Mg/(Mg + Fe2+)] and NiO contents than olivine in harzburgite. These dunites are probably of cumulate origin as it is also indicated by their enrichment in Pt and Pd (<= 17.92 ppb). Micro-textural and Re-Os isotopic data support that clinopyroxenite intrusions do not have a pure magmatic origin and their formation was partly controlled by metasomatic processes. Overall data indicate that the eastern Orhaneli ultramafic rocks have a complex petrological history including various stages of partial melting, metasomatism and magmatism in an evolving from MOR to SSZ geotectonic setting.
AtıfScopus17WoS14OpenAlex15İncele - MakaleAçık Erişim2017Scopus SJRQ4Synthesis of some natural sulphonamide derivatives as carbonic anhydrase inhibitors
Gokcen, Taner; Al, Melike; Topal, Meryem; Gulcin, Ilhami; Ozturk, Turan; Goren, Ahmet C.
Carbonic anhydrase inhibitor; sulphonamides; p-hydroxybenzoic acid; 3,4,5-trihydroxybenzoic acid (gallic acid).Carbonic anhydrase inhibitors are both in clinical use as antiglaucoma, diuretics, antiepileptics and management of altitude sickness, and under investigation as anticancer, anticonvulsant and antiobesity agents. Sulphonamides have been known for decades as carbonic anhydrase inhibitors and are in clinical use. Sulphonamide derivatives of p-hydroxybenzoic acid and 3,4,5-trihydroxybenzoic acid (gallic acid) were synthesized and their inhibition values over hCA I and hCA II isozymes, purified from human erythrocyte cells by Sepharose-4B-L-tyrosine-sulphanilamide, were determined. Compounds synthesized showed efficient carbonic anhydrase inhibition activity at low nM levels.
AtıfScopus27WoS24OpenAlex27İncele - MakaleAçık Erişim2017Scopus SJRQ3Synthesis, in vitro DNA interactions, cytotoxicities, antioxidative activities, and topoisomerase inhibition potentials of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes with azo-oxime ligands
Ayvaz, Melekcol; Turan, Ibrahim; Dural, Bayram; Demir, Selim; Karaoglu, Kaan; Aliyazicioglu, Yuksel; Serbest, Kerim
Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) transition metal complexes of 2-hydroxy-5-[(E)-(4-phenyl) diazenyl] benzaldehyde oxime and 2-hydroxy-5-[(E)-(4-nitrophenyl) diazenyl] benzaldehyde oxime ligands were synthesized and characterized through NMR, IR, ESI mass, and UV analysis. DNA binding abilities of the complexes were revealed using a UV-Vis spectrophotometer with the absorption titration and competitive binding techniques. Hydrolytic and oxidative DNA cleavage activities under different conditions were also proved. Topoisomerase I inhibition efficiencies and in vitro free radical scavenging activities of all complexes were examined. Finally, the selective cytotoxic potentials of all complexes were evaluated in human colon cancer, normal colon, and fibroblast cell lines using the water-soluble tetrazolium salt (WST-1) assay. The complexes had the ability to intercalate into stacked base pairs of DNA and topoisomerase I activity was reasonably inhibited in their presence in 0.4 mM concentrations. The abilities for scavenging of DPPH and hydroxyl radicals were found to be higher than those of known standard antioxidants (ascorbic acid, butylated hydroxyanisole, and mannitol). The results obtained from the cytotoxicity experiments are especially promising for further research, which must be carried out for the evaluation of the studied complexes as anticancer drugs.
AtıfScopus8WoS8OpenAlex8TR Dizin2İncele - MakaleAçık Erişim2017Scopus SJRQ2Accumulation of phenolics in natural and micropropagated plantlets of Thymus pseudopulegioides Klokov & Des.-Shost. with their antioxidant potentials
Günaydin, Mustafa; Laghari, Abdul Hafeez; Bektas, Ersan; Sökmen, Munevver; Sökmen, Atalay
Thymus pseudopulegioides plantlets were propagated in vitro via direct organogenesis by using Murashige and Skoog (MS) media containing kinetin, thidiazuron, and 6-benzyladenine (BA) individually. Methanol extracts obtained both from plantlets and wild plants were analyzed for their total phenolics and flavonoid contents, then quantified by HPLC. The highest total phenolic (8.83 mg/g as gallic acid equivalent) and total flavonoid (0.92 mg/mL as rutin equivalent) values were from the MS media supplemented with 1.0 mg/L kinetin and 0.5 mg/L BA, respectively. The plantlets grown in those media also showed remarkable antioxidant activities with an IC50 value of 4.77 mu g/mL in DPPH and 100% inhibition in beta-carotene assays, respectively. HPLC analysis proved the production of protocatechuic, caffeic, vanillic, rosmarinic, ferulic, and o-coumaric acids and rutin. Rosmarinic acid production was predominant in natural samples (115.2 mg/100 g dry weight), while the aforesaid phenolic acids were prevalent in plantlets grown on MS media supplemented with KIN or BA at various concentrations. Rutin production was the highest (50.74 mg/100 g dry weight) in the plantlets grown on MS medium containing kinetin (1.0 mg/L). As an economically important chemical, rosmarinic acid was selected as the target chemical and a novel method was introduced to achieve its selective isolation.
AtıfScopus6WoS5OpenAlex9TR Dizin2İncele - MakaleYalnız künye2017Scopus SJRQ2Microindentation on the porous copper surface modulations
Ekmekci, Dursun; Yilmaz, Fikret; Kölemen, Ugur; Cora, Omer Necati
This study aimed to investigate the mechanical properties of a surface modulation which was realized through compaction, and then sintering of copper powders. To this goal, Berkovich type of indenter and depth-sensing indentation technique were used in microindentation to measure the hardness and modulus of elasticity values at different features of compact. Indentations were performed with a peak force of 50 mN. Hardness values were obtained in 0.88-1.12 GPa range while the modulus of elasticity was recorded in the 70-111 GPa interval. Even though both modulus of elasticity and hardness values were noted to be different for copper powders and substrate, one-way ANOVA analyses showed that the differences in both modulus of elasticity and hardness values are insignificant. FE modeling of microindentation was also performed and validated. It was shown that the force-displacement values obtained from FE analyses are quite well in agreement with the experimental data.
AtıfScopus4WoS5OpenAlex4İncele - MakaleYalnız künye2016Changes in fatty acid composition of hazelnut during fruit development
İlyasoğlu, Huri
Fındık oleik asit gibi tekli doymamış yağ asitleri bakımından zengindir. Fındığın yağ asidi kompozisyonusağlık yararları nedeniyle önem kazanmıştır. Bu çalışmanın amacı, meyve gelişimi sırasında Türk fındıkçeşitlerinde yağ asidi kompozisyonundaki (Tombul, Palaz ve Sivri) değişimleri değerlendirmektir. Tümfındık çeşitlerinde tüm gelişim dönemlerinde, dört makro yağ asidi (oleik, linoleik, palmitik ve stearikasit) ve üç minör yağ asidi (palmitoleik, linolenik ve araşidik asit) tespit edilmiştir. Meyve gelişimisırasında Türk fındık çeşitlerinde tekli doymamış yağ asitleri içeriği artarken, çoklu doymamış yağ asidiiçeriği azalmaktadır. Bu sonuçlar, meyve gelişimi sırasında fındık yağının oksidatif stabilitesininartabileceğini göstermiştir
- MakaleYalnız künye2016Ekşi hamur fermantasyonunun ekmeğin biyoaktif bileşenleri ve biyoyararlanımı üzerindeki etkileri
Hendek, Muge; Hayta, Mehmet
Ekşi hamur çok uzun yıllardır ekmek üretiminde kullanılmakta olup, ekmeğin kalitesini ve raf ömrünüolumlu yönde etkileyen geleneksel bir üründür. Un, su ve ortamdan gelen mikroorganizmaların etkisiylehamurun doğal fermantasyona uğraması veya starter olarak laktik asit bakterilerinin (LAB) un, su karışımınailave edilmesi sonucunda oluşmaktadır. Her iki yöntemde de, ekşi hamur LAB mikroflorasının niteliklerinegöre meydana gelen metabolitler, ekmeğin besinsel, lezzet, tekstürel ve diğer fizikokimyasal niteliklerinietkilemektedir. Ekşi hamur fermantasyonu sonucu meydana gelen biyokimyasal değişiklikler vemetabolitler sayesinde, ekmeğin biyoaktif bileşenleri ve bunların biyoyararlanımında da değişimmeydana gelmektedir. Bunlar, protein ve mineral biyoyararlanımında artış, biyoaktif bileşen içeriğindezenginleşme ve değişim, dirençli nişasta içeriğinde yükselme, eksopolisakkaritlerin oluşumu, gliadin(çölyak hastaları için toksik protein) degradasyonu, nişastanın mikrobiyel hidrolizi ile ekmeğin sertleşmesininve bayatlamasının önlenmesi, diyet lif içeriğinde yükselme, fitaz aktivitesinde ve safra bağlama kapasitesindeartış, fenolik bileşiklerin etkisiyle ortaya çıkan antioksidan aktivite gibi çoğu besinsel açıdan olumluetkilerdir
AtıfTR Dizin9İncele - MakaleYalnız künye2016Yönetim kurulu çeşitliliği ve kurumsal sosyal sorumluluk söylemleri arasındaki ilişki
Nas, Tülay İlhan; Koparan, Emrah; Okan, Tarhan
Bu araştırmanın amacı, yönetim kurulu çeşitliliği ve kurumsal sosyal sorumluluk (KSS) söylemleri arasındaki ilişkide faaliyet gösterilen ülkeye ait kurumsal çevrenin moderatör etkisini ortaya koymaktır. İlgili literatür çerçevesinde geliştirilen araştırma hipotezleri 30 ülkeden seçilen 192 işletmeden, nitel ve nicel veri toplama araçları bir arada kullanılarak elde edilen veriler ile test edilmektedir. Elde edilen bulgular, kurulda yer alan kadın üye oranı ve Ph.D. derecesine sahip üye oranı ile KSS arasında pozitif yönlü bir ilişkiye kanıt sağlarken, MBA derecesine sahip üye oranı için elde edilen ilişki negatif yönlüdür. Analiz sonuçları YK çeşitliliği ile KSS arasındaki bu ilişkilerin kurumsal çevre boyutları olarak ele alınan düzenleyici, normatif ve bilişsel çevrenin güçlü ve zayıf düzeylerine göre farklılaşacağını ifade eden moderatör hipotezlere de çeşitli düzeylerde kanıt sağlamaktadır
AtıfTR Dizin6İncele - MakaleYalnız künye2016Osmanlı Devleti'nde Şeker Üretimi (1840-1908)
Damlıbağ, Fatih
Historically only sugar source plant was sugar cane. For the Ottoman Empire, this situation did not also differ. Especially sugar cane cultivator southern provinces were main sugar providing areas of the Ottoman Empire. But with 17th century, strong American competition considerably diminished Ottoman sugar production. Hereafter, sugar became imported goods for Ottoman people. But invention of sugar extraction from beet took attention of many entrepreneurs to this sector. Primarily sugar had already great market in the Ottoman Empire. Moreover sugar beet cultivation has much more advantages than sugar cane. Beet requires less irrigation and it was resistant to lower temperatures. That means many regions of the Ottoman Empire could be opened sugar production. In this article, time period was held quite a long; because sugar manufacturing was not very common activity in the Ottoman Empire in this period. In general, sugar production entrepreneurs could be divided in to two parts. In the beginning, Dimitri Efendi, Davutoğlu Karabet and Monsieur Michel planned to establish their factories in İstanbul and İzmir for transportation facilities and closeness to main consumption centers. But after 1890's, new entrepreneurs took into account raw material needs in their investment plans. All newly chosen places were either former cultivation centers or very convenient places for sugar cane or beet agriculture. This attitude was very important, because sugar production was completely dependent to rapid raw material flow in that time and also today. The Ottoman Empire granted every possible facility to sugar producers to decrease trade deficit. As to entrepreneurs, some of them remained on paper. But Monsieur Michel founded a factory for experimentation. Rauf Pasha started beet cultivation and sent them to analyze for learning sugar content. But in general, sugar production entrepreneurs were not successful. Because sugar remained an important part of import, up to end of the Ottoman Empire.
- MakaleYalnız künye2016Sağlıkta dönüşüm programı hakkında yönetici ve çalışan görüşlerinin karşılaştırılması üzerinden değişime direncin ölçülmesi
Bostan, Sedat; Köse Ünal, Aslı
Bu çalışmanın amacı öncelikle hastane yöneticileri ve sağlık çalışanlarının sağlıkta dönüşüm programı uygulamalarıyla gerçekleşen değişimi nasıl değerlendirdiklerini belirlemektir. İkinci olarak değişimin planlayıcısı olan üst yönetim tarafından atanan ve üst yönetimi temsil ettiği varsayılan hastane yöneticileri ile değişimin ortaya çıkardığı belirsizlik karşısında direnç göstermesi beklenen sağlık çalışanlarının görüşlerini karşılaştırmaktır. Son olarak elde edilen sonuçlar üzerinden sağlıkta dönüşüm programı uygulamalarına karşı sağlık çalışanlarının direnç düzeylerini belirlemektir. Bostan (2009) tarafından hastane yöneticileri ve sağlık çalışanlarına uygulanmak üzere oluşturulan sağlıkta dönüşüm programı değerlendirme ölçeği bu çalışmada kullanılmıştır. Ölçek geçerlenip, güvenirliği test edilmiştir. Araştırma kapsamında Türkiye genelinde 75 ilde 284 hastanede 779 hastane yöneticisi ve 774 sağlık çalışanına ulaşılmıştır. Çalışmadan elde edilen veriler istatistiksel programlarla analiz edilmiştir. Elde edilen bulgulara göre sağlık çalışanları ve hastane yöneticilerinin sağlıkta dönüşüm programı uygulamalarını paralel, fakat istatistiksel olarak anlamlı düzeyde farklı değerlendirdikleri görülmüştür. Hastane yöneticilerinin değerlendirme düzeyleri değişime direnç ölçeği açısından genel olarak çoğunlukla kabul, diğer durumlarda kayıtsızlık düzeyinde bulunmuştur. Sağlık çalışanlarının değerlendirmeleri ise genel olarak pasif direniş ve kayıtsızlık düzeyinde belirlenmiştir. Özellikle sağlık çalışanlarının kendi durumlarıyla ilgili ifadelerde her iki grubunda değerlendirme puanları düşmekte ve direnç artmaktadır. Bu sonuçlardan hareketle özellikle sağlık çalışanlarının değişime direnç gösterdiği söylenebilir. Sağlık çalışanlarının kaygılarının azaltılması yönünde çalışmaların yapılması önerilmektedir.
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