Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Kaygusuz, Abdullah(35)
- Sipahi, Ferkan(35)
- Karsli, Orhan(34)
- Dokuz, Abdurrahman(30)
- Duran, Celal(30)
- Kandemir, Raif(29)
- Ozdes, Duygu(28)
- Maden, Nafiz(27)
- Uzun, Sevda(27)
- Merdan, Mehmet(26)
- Vural, Alaaddin(26)
- Öztürk, Serkan(25)
- Araz, Onur(24)
- Kulakaç, Nurşen(24)
- Ashyralyyev, Charyyar(23)
- Yildiz, Salih(23)
- Yilmaz, Ozgur(23)
- Doğan, Kadir Caner(21)
- Arslan, Mehmet(20)
- Aydin, Faruk(20)
- Doğru, Bülent(20)
- Bayraktar, Alemdar(19)
- Kankal, Murat(19)
- Ayaydin, Hasan(18)
- Baltaci, Cemalettin(18)
- Yolcu, Halil(18)
- Cakir, Tufan(17)
- Cengiz, Ekrem(17)
- Demir, Selim(17)
- Gücer, Mehmet Ali(17)
- Akaryali, Enver(16)
- Artan, Seyfettin(16)
- Hayaloğlu, Pınar(16)
- Kaya, Afşin Ahmet(16)
- Tosunoğlu, Büşra(16)
- Uysal, Ibrahim(16)
- Kurt, Kemal(15)
- Ozturk, Samet(15)
- Reis, Hatice Catal(15)
- Aksakal, Vecihi(14)
Yayınlar
- MakaleYalnız künye2020Scopus SJRQ4Betting on the Future: A Comparison Macroeconomic Dynamics of Labour Income Share in The United States: Evidence From MARS
Çelik, Orkun
Macroeconomic dynamics of the labour income share (herein: lis) in the United States for the period of 1948Q1-2019Q1 are tried to be determined in this study, where the Multivariate Adaptive Regression Splines (will be referred to herein as MARS) approach is employed. In order to investigate sectorial differences, the business, non-farm, and non-finance sectors are evaluated, respectively. In accordance with the results obtained, it may be observed that the macroeconomic dynamics of lis in the business sector are productivity, export, profit, gross private domestic investment, unemployment rate, current account balance, gross domestic product, and tax revenue, respectively. Related macroeconomic dynamics of lis concerning non-farm sector are productivity, current account balance, gross private domestic investment, export, consumer price index, gross domestic product, profit, unemployment rate, and gross government investment.
- Kitap BölümüYalnız künye2020UNDERSTANDING THE BOLSA FAMILIA PROGRAM AS A SOCIAL PROTECTION SYSTEM IN BRAZIL
Beken, Hikmet Gulcin; Dobreva, J; Alaverdov, E; Yildirim-ahin, E
Launched in Brazil as of 2003, Bolsa Familia is an example of conditional cash transfer programs. Under Bolsa Familia, extending support to the poorest groups is targeted by fighting against poverty and alleviating inequality. Besides, preventing poverty from being transmitted across generations and supporting the human capital in terms of education and healthcare are also targeted. Bolsa Familia constitutes the social protection system of the country along with integration of both social insurance and social support programs. Bolsa Familia was transformed into a more comprehensive program by gathering previous programs implemented in the country under a single roof, and it allowed the government to reduce administrative costs. In this study, the focus will be placed on the effect of Bolsa Familia on the fight in the country against poverty and inequality by a theoretical analysis.
- Kitap BölümüYalnız künye2020SOME LITTLE-KNOWN ASPECTS OF OTTOMAN WAQFS AND THEIR FUNCTION IN SOCIAL WELFARE ECONOMY
Karademir, Aysenur; Dobreva, J; Alaverdov, E; Yildirim-ahin, E
The expression of for the benefit of society or, ibadullahin terfihi ahvalleri which appeared in the court registers was a brief but nevertheless powerful summary of Ottoman economic and social perceptions. The Ottomans genuinely believed in this principle and, their whole social and economic life revolved around it. In this way, while they maintained the balance between rich and poor in social life, they benefited from Islamic pious foundations, waqfs, as a tool for delivering social projects. From education to health, the waqf institution provided all the services for the public, obviously supported by the Ottoman sultans. They built hospitals, soup-kitchens, universities and many other buildings, hayrat, under the management of waqfs, and they encouraged their families and government officials to do the same. Although the hayrat was the visual representation of the institution, waqf meant much more than just a building in the Ottoman economic and social understanding. In this chapter, I dig a bit deeper and, analyse some little-known aspects of Ottoman waqfs, specifically the waqfs of the state officials, referred to in the literature as sultanic and vizirate waqfs. The purpose of this study is to set out details from works which have analysed original archival sources and, to present a wide perspective on Ottoman waqf practice.
- MakaleYalnız künye2020The Effect of Remittances on Financial Development in Developing Countries: Dynamic Panel Data Analysis
Akbulut Yildiz, Gizem
The aim of the study is to measure the effect of workers' remittances on financial development. The study on 44 developing countries covers the period 1994-2017. In the empirical analysis of the study, financial development index data was used as the dependent variable. However, financial institutions and financial markets index data, which are the sub-criteria of the index, are also used in the study as dependent variables. As independent variables, workers' remittances, GDP per capita, trade openness and inflation data are used. According to the results of the analysis made using the Two-Stage System Generalized Moments Method, workers' remittances, per capita GDP and trade openness, financial development, financial institutions and financial markets are statistically significant and positive, while inflation is negatively.
- MakaleYalnız künye2020The Effect of Defense Sports on the Treatment of Attention-Deficit/Hyperactivity Disorder in Children
Bayrakdaroglu, Serdar; Tekin, Ali
Attention-deficit/hyperactivity disorder is a significant problem in children. Primarily pharmacological, educational, cognitive-behavioural and multi-model intervention techniques are used to treat this disorder. The success level differs with advantages and disadvantages of each technique and any single technique is not sufficient. In recent years, the positive aspects of physical exercise used in treatment alone or in combination with other techniques has made the different types of physical exercise worthy of investigation. This review aims to summarize the scientific evidence obtained through literature on the effects of defense sports in the treatment of attention-deficit/hyperactivity disorder in children. The results showed that the most beneficial sports are Taekwondo, Karate, Judo and Tai Chi. There are studies supporting the positive effect of the use of defense sports in treatment with few exceptions, but it is quantitatively insufficient. Therefore, new studies are needed to test the effect of different defense sports on a sufficient number of different samples representing the related population.
AtıfWoS1
İncele - MakaleYalnız künye2020The Effects of Explosive Strength Applied to Footballers on Some Physical and Physiological Parameters
Zambak, Omer; Sever, M. Onur
It is aimed to investigate the effects of explosive strength training on aerobic capacity, anaerobic capacity, blood pressure, resting heart rate and shooting speed. The aim of this study was to investigate the explosive strength training on some physical and physiological parameters. The study included 38 volunteer 1st and 2nd amateur league footballers aged 1825 years. Aerobic capacities of the players were measured by shuttle run test and Anaerobic power measurement by vertical jump test. After calculating the vertical jump value of the athletes anaerobic strength; calculated using the Lewis Nomogram using vertical jump and body weight values. The shooting speed of the players was determined by speed pocket radar equipment In the study, different strength training (station training method) and football-specific technical and tactical training programs were applied to the research group for 8 weeks, 3 days a week. only technical and tactical training programs were applied to the control group. The parameters were taken twice before and after the 8-week study. In order to determine the differences between the pre-test and post-test results, The Wilcoxon test, one of the nonparametric tests, was used to, Mann Whitney U-test analysis was used to compare the pre-test and post-test values between the groups. The significance level of the study was accepted as p<0.05. Significant difference in shooting speed was found as a result of the signed ranks test comparing the pre-test and post-test measurements of the research group participants (p<0,05). Significant differences between the measurements of aerobic power, anaerobic power were found as a result of the signed ranks test comparing the pre-test and post-test values of the control group participants (p<0,05). After the Mann-Whitney U test, where the posttest measurement values of the experimental and control group participants were compared, there was a significant difference between the groups in aerobic power values, and this difference was found to be in favor of the experimental group participants (p <0.05). As a result, it can be said that explosive strength training applied to amateur football players between the ages of 18 - 25 increases the shooting speed.
AtıfWoS1İncele - MakaleYalnız künye2020Scopus SJRQ4Hepatic venous Doppler assessment can anticipate simplified pulmonary embolism severity index and right ventricle dysfunction in patients with acute pulmonary embolism
Acar, Emrah; Izci, Servet; Inanir, Mehmet; Yilmaz, Mehmet F.; Izgi, Ibrahim A.; Gokce, Mustafa; Kirma, Cevat
Purpose Acute pulmonary embolism (APE) is a life-threating cardiothoracic thromboembolic emergency in which right ventricle dysfunction (RVD) is a major concern. In the present study, we examined the hepatic veins (HVs) blood flow with pulsed-wave spectral Doppler ultrasonography to determine its relationship with the simplified pulmonary embolism severity index (sPESI) and the patient's RVD status. Methods We divided the 243 patients who met the inclusion criteria into two groups based on both their sPESI scores and their RVD status. Transthoracic echocardiography was performed to evaluate the RVD and the HVs within 1 hour after patient admission. The liver was evaluated using subcostal and intercostal echocardiographic windows in grayscale B-mode, and HVs were assessed using color and spectral Doppler assessment though the same echocardiographic windows. Result A cut-off value of the systolic reverse flow velocity-time integral (SrVTI) = 2.2 cm carried a sensitivity and specificity of 84.29% and 74.89%, respectively, for the prediction of sPESI >= 1. A SrVTI cut-off value of 2.1 cm yielded a sensitivity and specificity of 83.03% and 73.91%, respectively, for the prediction of RVD. Conclusion HV Doppler assessment could be a useful method for anticipating the sPESI and the presence of RVD in patients with APE. In addition, it may provide information regarding the hemodynamic impact of APE.
AtıfWoS3OpenAlex3
İncele - MakaleYalnız künye2020Scopus SJRQ3Right Ventricular Early Inflow-Outflow Index-A new method for echocardiographic evaluation of right ventricle dysfunction in acute pulmonary embolism
Acar, Emrah; Izci, Servet; Inanir, Mehmet; Yilmaz, Mehmet Fatih; Izgi, Ibrahim Akin; Kirma, Cevat
Introduction Acute pulmonary embolism (APE) is a cardiothoracic thromboembolic emergency at risk of life-threatening. Several risk graduation algorithms may be applied to delineate short-term mortality in patients with APE. In this study, we aim to depict the relationship between the right ventricular early inflow-outflow (RVEIO) index, which is a Doppler-based parameter, and the pulmonary embolism severity index(PESI) in acute pulmonary embolism. Methods In the presented study, a total of 160 patients who were diagnosed with APE using pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were comprised. Patients were separated to 2 groups based on the simplified PESI (sPESI): sPESI < 1 (n = 88) and sPESI >= 1 (n = 72). Echocardiographic parameters, including the RVEIO index, were measured. Results There were no significant differences between the groups in age and gender distribution, or the presence of diabetes mellitus, hypertension, smoking, and history of coronary artery disease. There was a positive correlation with the mortality rate and RVEIO index; the mortality was higher in patients with a higher RVEIO index(<0.001). In receiver operating characteristic (ROC) curve analysis using a cutoff level of 14.39, RVEIO index predicted mortality with a sensitivity of 80.4% and specificity of 57.6%(ROC area under curve:0.694; 95%CI, 0.581-0.814; P < .001). RVEIO index was higher in the sPESI >= 1(n:72) than in the patients with sPESI < 1(14.27 +/- 2.13 vs 10.63 +/- 2.09; P < .001). There was a positive correlation between RVEIO index and sPESI score(+0.428; P < .001). Conclusion As well as predicting the degree of tricuspid regurgitation (TR), the RVEIO index is well-correlated with sPESI score and is associated with mortality in patients with APE. This easily measurable parameter may be used to predict short-term mortality in APE patients.
AtıfWoS4İncele - MakaleYalnız künye2020Scopus SJRQ3Potential therapeutic effects of ethyl pyruvate and N-acetyl cysteine in an experimental rat model of corrosive esophageal
Tatli, Ozgur; Pasli, Sinan; Imamoglu, Melih; Cicek, Mustafa; Yadigaroglu, Metin; Sahin, Aynur; Dilaver, Irem; Yulug, Esin; Karaca, Yunus
Background and study aims: Esophageal burns due to ingestion of corrosive substances are frequently seen in both children and adults. However, there is no standard method of treatment to prevent associated mortality and morbidity. Therefore, this study aimed to evaluate the effects of known antioxidants, namely N-acetyl cysteine and ethyl pyruvate, on esophageal damage due to sodium hydroxide-induced corrosive burns. Materials and methods: Thirty-five female rats were randomly assigned to five equal groups. Group 1 was the sham group, while Group 2 was the control group. Group 3 received N-acetyl cysteine, Group 4 received ethyl pyruvate, and Group 5 received both N-acetyl cysteine and ethyl pyruvate. Rats in the burn groups were gavage-fed with 0.2mL of 25% NaOH. All esophagi were extracted on day 4 for histopathological evaluation. Results: Total histopathological damage scores were evaluated at the end of the study. Groups 3 and 5 were significantly different from the control group in terms of total histopathological scores (p = 0.001), while no significant difference was seen with Group 4. Stenosis index results in groups 3 and 5 were similar to those seen with total histopathological scores (p = 0.004). Conclusion: N-acetyl cysteine, alone or in combination with ethyl pyruvate, may be useful in the treatment of esophageal damage associated with corrosive substances and in achieving histopathological improvement in an experimental setting. (C) 2020 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved.
AtıfWoS4OpenAlex3İncele - MakaleYalnız künye2020The Examination of Trait Anxiety Level of Referees in Different Branches (The Sample of Mugla)
Onturk, Yavuz; Bingol, Erkan; Efek, Engin; Bayrakdaroglu, Yesim; Gorun, Levent
The aim of this study to examine the trait anxiety level of referees in different branches in terms of some variables. For the model of the research, the survey model, one of the quantitative research types, was chosen. While the population of the research is composed of referees working in different branches in Mugla Province, the sample is composed of 167 referees who have been chosen by a randomized sampling method and participated in the research voluntarily. The authors designed a personal information form for the demographical information of the participants. The Trait Anxiety Inventory developed by Spielberger, Gorsuch and Luschene (1) (1970) and adapted to Turkish by Oner and Le Compte (2) (1983) was used to determine the participants' anxiety levels. The data obtained from the form and scale used were analyzed using the SPSS 17 package program. Frequency, percentage, average, and standard deviation values were used in the analysis of the data. Data normal distributions were analyzed with Skewness-Kurtosis values. Since the data showed normal distribution, t-test and ANOVA test, which are parametric tests, were used, and the significance level was accepted as p <0.05. According to the findings of the study, while the anxiety levels of the referees showed significant differences in terms of gender, they did not display a significant difference with the variables of age, education level, refereeing time and refereeing classification. Consequently, the trait anxiety levels of female referees are significantly higher in favor of the trait anxiety levels of male referees. This study revealed that anxiety-reducing training should be focused on reducing the trait anxiety situations that female referees experience more than male referees.
- MakaleYalnız künye2020Economic Analysis of the Use of Reclaimed Asphalt Pavement (RAP) Materials in Plant-Mix Base Courses
Seferoglu, Aysegul Gunes; Seferoglu, Mehmet Tevfik; Akpinar, Muhammet Vefa; Çelik, Muhammet
The aim of this study is to determine the financial benefits to be gained based on the percentages of reclaimed asphalt pavement (RAP) material suitable for use in plent-mix courses (PBCs) to be designed according to the specification of Turkey Department of Transportation. Cost analysis of all RAP mixtures were made considering the construction of the plant-mix base course and the transportation costs of the materials, it was researched that the use of RAP would be an economical application in terms of how far the RAP material was taken. As a result of the study, it has been determined that the use of 100% RAP material in PBC is possible with cement reinforcement and it provides a profit of more than 16% in terms of costs in case of using virgin aggregate (VA) instead. RAP material is an alternative to virgin aggregate and is a more economical material in terms of cost.
AtıfWoS1İncele - Kitap BölümüYalnız künye2020Geothermal Potential and Circulation Depth of Hudai Thermal Springs (Sandikli-Afyonkarahisar, Turkiye) Using Magnetic, Geothermometry and Heat Flow Data
Maden, Nafiz; Afsin, Mustafa; Aksever, Fatma; Davraz, Aysen; Biswas, A; Sharma, SP
The Hudai-Sandikli geothermal basin having 23 thermal productivity wells is a significant geothermal energy source field. The analysis of power spectrum, conventional heat flow and silica heat flow methods were implemented to identify the geothermal waters circulation depth, depth to Curie point and surface heat flow rate in the Hudai-Sandikli geothermal field. Hydrogeochemical facies of geothermal immature ancient waters having deep circulation in lower hydraulic conductive aquifers are Na-Ca-HCO3-SO4 and Na-Ca-SO4-HCO3, which is represented very high ion content because of extensive contact with rocks. The heat conduction law is employed to specify the rate of heat flow using the geothermal gradient value. The numerical results determined from silica geothermometer method, the mean heat flow density and Curie temperature depth are obtained as 103.69 mWm(-2) and 11.81 km, respectively. The study region was represented by a mean geothermal gradient of 49.18 degrees C km(-1) yielding average reservoir depths of 0.90 km. The estimated Curie temperature, heat flow, reservoir temperature values demonstrated that the region indicates significant geothermal energy potential because of the partial melting of lithospheric crust.
AtıfWoS1OpenAlex3İncele - MakaleYalnız künye2020Scopus SJRQ4Some physicochemical and microbiological properties of butter produced in Erzurum
Akgül, Halil Ibrahim; Sengül, Mustafa; Ürkek, Bayram; Kotan, Tuba Erkaya; Gürbüz, Zeynep
The goal of this study was to determine some physicochemical and microbiological properties of Erzurum butter. Random samples (n = 30) were collected from different retail markets throughout Erzurum province. The pH, acidity, and melting point values of samples were 3.88, 0.47%, and 30.03 degrees C, respectively. The salt, fat, and moisture values of some samples (sample no 1, 14, and 18) were not harmony with Turkish Food Codex. The highest and lowest peroxide, iodine, saponification, Reichert-Meissl (RM), and Polenske values were found to be in the range of 0-0.51 mEqO2/kg, 22.97-38.64, 195.45-228.54, 17.08-30.-56, and 0.72-1.80, respectively. The refractive index value (RI) was changed from 1.4591 to 1.4620. Total coliforms, aerobic mesophilic bacteria (TAMB), lactic acid bacteria (cultured in MRS and M17), and mould and yeasts mean counts were 1.07 log CFU g-1, 6.79 log CFU g-1, 6.45 log CFU g-1, 6.76 log CFU g-1, and 5.33 log CFU g-1, respectively. There were high differences in physicochemical and microbiological properties of butter might be attributed to a non-standard production process as well as non-standard raw material. In sum, the sanitation and storage conditions should be improved from production to consumption to improve the butter quality.
AtıfWoS1İncele - MakaleYalnız künye2020Scopus SJRQ4DETERMINING THE FORAGE YIELD AND CERTAIN CHARACTERISTICS OF SOYBEAN (GLYCINE MAX.L.) VARIETIES WITH DIFFERENT SOWING DATES
Okcu, Melih; Yolcu, Halil
This research was conducted at Gumushane University, in the field of application of Gumushane University Vocational School of Higher Education during 2014-2015. The research was carried out in 3 replications according to the exact blocks trial pattern of chance during the season of breeding between 2014 and 2015. in the research Nova, Arisoy, A-3127, Sa-88, Ataem-7, Bravo, Yesilsoy and Yemsoy varieties were used, and different three sowing dates (1 April,15 April, 30 April). According to the results, the highest values in terms of green grass and ADF values were given by Yesilsoy cultivar. Yesilsoy cultivar took the first place with 12123.3 kg / ha(-1) in terms of green grass yield. In terms of hay yield, Arisoy cultivar gave the highest value with 5003 kg / ha(-1). The highest values in ADF, NDF and Crude protein content were Bravo 37.51%, Ataem-7 37.48%, Bravo 46.72%, Yesilsoy 46.48%, Bravo 13.96%, Ataem-7 13%, 95 respectively gave the highest values. In terms of sowing time, sowing time of 1 April gave the highest results among the parameters examined. Therefore, while sowing time on April 1 was determined as the most suitable planting, Nova, Arisoy, Ataem-7, Yesilsoy and Yemsoy varieties were the prominent varieties in terms of green, dry grass and crude protein.
- MakaleYayıncıda açık erişim2020Complementary and Alternative Medicine Methods Used for Sleep Disturbance in Menopause
Özcan, Handan; Çakmak, Suzan; Salman, Ebru
Objective: One of the most common complaints observed during the menopausal period is sleep disorders, affecting 40%-60% women. In this study, we aimed to determine complementary and clternative medicine (CAM) for menopausal women experiencing sleep disturbances, and the prevalence and influencing factors of sleep disturbance. Materials and Methods: In this descriptive cross-sectional study, we included menopausal women experiencing sleeplessness [>= 4 degree of discomfort according to the Visual Analog Scale (VAS)] (n=201). A questionnaire and the CAM Scale were used to collect data. The necessary institutional and ethical committee permissions were obtained. Results: The mean age of the menopausal women was 47.23 +/- 4.53 [minimum (min)- maximum (max), 30-60] years, and their mean VAS for insomnia was 5.20 +/- 1.12 (min-max, 4-9). The following methods were used by the women to overcome insomnia: herbal supplements (96.6%), dietary supplements (98.8%), religious practices (95.7%), and mind-body practices (76.9%). The most common methods were fruits and vegetables, milk and dairy products, honey, linden tea, rosehip, prayer, pray, and music. Approximately 70.5% women expressed that the method they used was effective. Conclusion: Almost all menopausal women used any method of CAM. Further studies on the effectiveness of these methods as well as the training to be provided and the information dissemination by healthcare professionals are recommended.
AtıfWoS7OpenAlex12TR Dizin4
İncele - MakaleYayıncıda açık erişim2020Proposal of a Structural Model about Social Media and Electronic Word of Mouth Communication in Political Marketing Process
Tehci, Ali; Yildiz, Salih
The purpose of this study is to investigate trust, loyalty and electronic word of mouth communication in relation to political marketing social media factor on voter behavior through a structural model. The survey data was obtained on the basis of the electronic questionnaire applied to 540 social media users. The data was analyzed in statistical package programs, the hypotheses were tested with structural equation model. As a result of the research, it has been reached that the political marketing social media factor affect to voter trust, loyalty and electronic word of mouth communication and these factors affect voter behavior.
AtıfWoS1TR Dizin1İncele - MakaleYalnız künye2020Scopus SJRQ2Process for production of microencapsulated anthocyanin pigments from Rosa pimpinellifolia L. fruits: optimization of aqueous two-phase extraction, microencapsulation by spray and freeze-drying, and storage stability evaluation
Odabas, Halil Ibrahim; Koca, Ilkay
Rosa pimpinellifolia L. fruits (RPF) are promising source of anthocyanin pigments. The objectives of this study were to optimization of the aqueous two-phase extraction (ATPE) process of anthocyanin from RPF and microencapsulation of anthocyanin-rich RPF extract. The optimal ATPE conditions were as follows: 0% HCl, 30% ethanol, 19% ammonium sulfate, and liquid to solid ratio 51.71, 97.71 min, and 30 degrees C extraction temperature. Predicted anthocyanin yield at the optimum conditions was 1578.90 mg cyanidin 3-glucoside equivalent/100 g dry fruit. ATPE resulting in 1.80-fold increase in the purity of anthocyanins when compared to conventional solvent extraction (CSE). The composition of the anthocyanins were determined with HPLC-QTOF-MS. Freeze-drying and spray-drying methods were employed for the production of microencapsulated anthocyanin pigments. The half times of microencapsulated anthocyanins at 4, 25 and 37 degrees C were determined as 12.16, 6.60 and 3.12months for freeze-dried microcapsules, and 16.50, 9.24 and 4.29 months for spray-driedmicrocapsules, respectively.
AtıfWoS13OpenAlex14İncele - MakaleYalnız künye2020Scopus SJRQ2Effect of Turkish Propolis on miRNA Expression, Cell Cycle, and Apoptosis in Human Breast Cancer (MCF-7) Cells
Misir, Sema; Aliyazicioglu, Yüksel; Demir, Selim; Turan, Ibrahim; Hepokur, Ceylan
Enriched in flavonoid compounds, phenol acids, and terpene derivatives, propolis has been shown to regulate apoptosis signaling pathways and alter the expression of microRNAs (miRNAs). In the present study, it has been aimed to examine the effects of Turkish propolis on miRNA levels of breast cancer (MCF-7) cells, and its relationship with cell proliferation and apoptosis. Cytotoxic activity of ethanolic propolis extract (EEP) was evaluated using MTT assay. Mechanisms involved in the cytotoxic action of Turkish propolis in MCF-7 cells were investigated with regard to apoptosis and cell cycle using flow cytometry and western blot. Mitochondrial membrane potential (MMP) were evaluated by spectrofluorometric method. miRNA levels were detected by qRT-PCR method. EEP exhibited selective toxicity against MCF-7 cells compared to normal fibroblast cells. EEP increased the cell cycle arrest at the G1 phase. EEP elevated the apoptotic cell death through increasing pro-apoptotic protein levels (p21, Bax, p53, p53-Ser46, and p53-Ser15), decreasing MMP and altering the expression levels of specific tumor suppressors (miR-34, miR-15a, and miR-16-5p) and oncogenic (miR-21) miRNAs. These data support that Turkish propolis may be evaluated as a potential natural agent for new anticancer drugs in future.
AtıfScopus42WoS43OpenAlex56
İncele - MakaleYalnız künye2020Scopus SJRQ2Determination of geological structures by geophysical and geotechnical techniques in Kırklartepe Dam Site (Turkey)
Sari, Mahmut; Seren, Aysel; Alemdag, Selcuk
In foundation research of engineering structures, application of geophysics methods before drilling work allows not only more economical studies but also a more detailed determination of underground sections. Especially in pre-feasibility studies on long tunnel routes, dam sites and lake areas, it has a vital importance in terms of structural safety to determine possible underground buried fault lines, lithology changes, anticlinal-synclinal structures and underground openings. By considering these effective factors, the alluvium/bedrock border and the positions of potential buried faults in the dam site and lake area in the Kırklartepe area of the province of Bayburt in northeastern Turkey were determined by comparison with geophysical and geotechnical methods. First of all, the resistivity of the dam axis location and the change of the Vp wave velocity by depth were determined by comparing the results between geophysical methods of electrical resistivity tomography (ERT) and seismic refraction tomography (SRT), respectively. Afterwards, from the foundation boreholes opened in the dam axis location, joint frequency and the other parameters determined by observations were obtained. With these parameters, 2-dimensional zoning profiles of the dam axis location were formed, and the alluvium-bedrock border and the locations of the buried faults were determined. Two potential faults in the NW-SE direction relative to the location of the dam axis were clearly revealed in the zoning profiles obtained in the ERT and SRT measurements. Additionally, the presence of these faults was determined as a result of examining the separation and joint frequency parameters from the drilling core samples collected from the BH_3 and BH_5 boreholes opened in the investigated area based on changes in the vertical and horizontal directions. In addition to these, in the ERT study, two potential faults other than the determined two were also detected. It was seen in the zoning profiles that these faults corresponded to right under the BH_2 borehole and 60 m SW of the BH_6 drilling. Consequently, in the zoning studies conducted at the examined site, the change in the lithology at the dam axis by depth (alluvium-bedrock border), lateral correlations of boreholes and potential faults were determined. It was recommended for the selected dam axis location to be constructed at a more suitable place in the NW direction in terms of engineering. Furthermore, with this study, it was revealed once again that it is highly essential to use geophysical and geotechnical together in conceptualizing large engineering structure projects.
AtıfScopus29WoS25OpenAlex30İncele - MakaleYalnız künye2020Scopus SJRQ4Plasticity in behavior of Turkish malting barley cultivars under semi-arid and continental climatic conditions
Sirat, Abdulveli; Bahar, Bilge
This study aimed to select stable cultivars in terms of desired agronomic or quality criteria from among 15 two rowed barley cultivars that may remain stable in varying year conditions during 2014-2015 and 2015-2016. Furthermore, relationships among these traits were investigated. Some agronomical and quality traits of barley were affected by years and cultivars. Yield, yield components and some quality parameters were affected by the cultivars. Also, days to ripening was affected by years, cultivars, and year x cultivar interaction. Crude protein content (CPC) was significantly positive correlated with ASH during both seasons. Starch ratio (SR) showed significantly negative correlations with ASH and CPC during both seasons. ADF and NDF had significant positive strong correlation with one another and ASH during both years while they showed significant negative correlations with SR. The results show that technological properties are not affected by the interaction of cultivar x year; therefore, these stable cultivars can be readily used in malt or feed technology if their technological features are considered. For example, cv. Unver contained low ratios of ash, CPC, oil, soluble fiber and high SR in the malt industry; cv. Hasat which includes the opposite technological properties of cv. Unver, was found be suitable for use in feed technology.