Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(87)
- Merdan, Mehmet(70)
- Duran, Celal(56)
- Baltaci, Cemalettin(52)
- Kulakaç, Nurşen(51)
- Ozdes, Duygu(51)
- Kaygusuz, Abdullah(47)
- Öztürk, Serkan(42)
- Demir, Selim(40)
- Karsli, Orhan(37)
- Turan, Ibrahim(37)
- Dokuz, Abdurrahman(36)
- Gücer, Mehmet Ali(36)
- Sipahi, Ferkan(36)
- Araz, Onur(35)
- Kandemir, Raif(31)
- Vural, Alaaddin(31)
- Topal, Fevzi(30)
- Kurt, Kemal(29)
- Ürkek, Bayram(29)
- Maden, Nafiz(28)
- Acet, Tuba(27)
- Alemdag, Selcuk(26)
- Arslan, Mehmet(26)
- Ayaydin, Hasan(26)
- Akaryali, Enver(25)
- Aydin, Faruk(25)
- Baltacı, Cemalettin(25)
- Yücel, Cem(25)
- Akar, Zeynep(24)
- Barut, Abdulkadir(24)
- Ozturk, Samet(24)
- Pala, Fahrettin(24)
- Peker, Iskender(24)
- Topal, Meryem(24)
- Yildiz, Salih(24)
- Öz, Mehmet(24)
- Aliyazicioglu, Yuksel(23)
- Bostan, Sedat(23)
- Kankal, Murat(23)
Yayınlar
- MakaleYalnız künye2016Scopus SJRQ2Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice
Dincel, Gungor Cagdas; Atmaca, Hasan Tarik
Toxoplasma gondii (T. gondii) is a protozoan parasite with the potential of causing severe encephalitis among immunocompromised humans and animals. Our previous study showed that T. gondii induces high nitric oxide (NO) production, high glial activation (GFAP) and neurofilament expressions, leading to severe neurodegeneration in toxoplasma encephalitis (TE) in the central nervous system (CNS). The aim of this experimental study was to investigate ADAMTS-13 expression and apoptosis in CNS and to identify whether they have any correlation with toxoplasmosis neuropathology and neurodegeneration. Mice were infected with ME49 strain T. gondii and the levels of ADAMTS-13, caspase 3, caspase 8, caspase 9, TNFR1 and Bcl-xL expressions were examined in brain tissues by immunohistochemistry, during the development and establishment of chronic infections at 10, 30 and 60days post-infection. Results of the study revealed that the levels of ADAMTS-13 (P < 0.005), caspase 3 (P < 0.05), caspase 8 (P < 0.05), caspase 9 (P < 0.005) and TNFR1 (P < 0.05) expressions in the brain markedly increased while Bcl-xL expression decreased (P < 0.005). The most prominent finding from our study was that 10, 30 and 60days post-infection ADAMTS-13 increased significantly and this may play an important role in the regulation and protection of the blood-brain barrier integrity and CNS microenvironment in TE. These results also suggest that T. gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of TE. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease. To the best of the authors' knowledge, this is the first report on ADAMTS-13 expression in the CNS of T. gondii-infected mice.
AtıfScopus31WoS29OpenAlex32
İncele - MakaleYalnız künye2016Scopus SJRQ1Theory of Justice, OCB, and Individualism: Kyrgyz Citizens
Özbek, Mehmet Ferhat; Yoldash, Mohammad Asif; Tang, Thomas Li-Ping
Research suggests that organizational justice (procedural, distributive, and interactional justice) has important impacts on work-related attitudes and behaviors, such as organizational citizenship behavior (OCB). In this article, we explore the extent to which individualism moderates the relationship between organizational justice and OCB (organizational obedience, participation, and loyalty) among citizens in Kyrgyzstan. We make additional contributions to the literature because we know very little about these constructs in this former Soviet Union country, Kyrgyzstan, an under-researched and under-represented region of the world. Results of our data collected from 402 managers and employees in Kyrgyzstan offer the following new discoveries. All three justice constructs are related to OCB. Individualism moderates only the distributive and interactive justice to OCB relationships. We develop an intricate theory with provocative implications: Procedural justice produces obedience. For “individualists,” interactional justice inspires loyalty and, interestingly, distributive justice “can only buy” participation, but “can’t buy” loyalty. Therefore, for individualists, interactional justice outweighs distributive justice for organizational loyalty. Based on Kyrgyz citizens’ justice, OCB, and individualism, our theory reveals novel insights regarding culture, money attitude, and intrinsic motivation and provides critical and practical implications to the field of business ethics.
AtıfScopus37WoS29OpenAlex47İncele - MakaleAçık Erişim2016Scopus SJRQ2Combustion Characteristics of Impregnated and Surface-treated Chestnut (Castanea sativa Mill.) Wood Left Outdoors for One Year
Fidan, Muhammed Said; Yaşar, Şekip Şadiye; Yaşar, Mehmet; Atar, Musa; Alkan, Elif
Treating wood with impregnating materials in order to improve resistance to burning is a commonly employed safety measure. In this study, chestnut (Castanea sativa Mill.) wood samples were impregnated using either Tanalith-E or Wolmanit-CB according to ASTM-D 1413-76 and surface-treated using water-based or synthetic varnish according to ASTM-D 3023. These samples were used to investigate the combustion characteristics of samples left outdoors for one year as detailed in ASTM-E 160-50. The combustion temperatures of the samples left outdoors were similar upon impregnation with either Tanalith-E or Wolmanit-CB. However, the combustion temperature of the samples treated with synthetic varnish was lower than those that were treated with water-based varnish. The time to collapse and the total duration of combustion of the samples left outdoors were shorter for those impregnated with Wolmanit-CB. Weight loss of the samples left outdoors was higher for those that were impregnated with Tanalith-E and treated with water-based varnish. Gas analysis of the samples that were left outdoors indicated that the O2 content of flue gas from samples that were impregnated with Wolmanit-CB and treated with synthetic varnish was high and the CO content of flue gas from the same samples was low.
AtıfScopus5WoS4OpenAlex8İncele - MakaleAçık Erişim2016Scopus SJRQ3Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells
Yalcin, Can; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Bahat, Zumrut; Misir, Sema; Deger, Orhan
Aim of Study: Propolis is a resinous bee product, rich of polyphenolic compounds and flavonoids. It is known that in different geographic zones its chemical composition varies due to the different plant sources. Many biological properties including antimicrobial, antioxidative, anti-inflammatory, antitumoral, antigenotoxic, antimutagenic, cytostatic activities have been ascribed to propolis. These biological effects are predominantly attributed to its content of polyphenols. In this study, we aimed to evaluate the radioprotective effect of ethanolic extract of Turkish propolis. (EETP) against γ-ray-induced DNA damage on fibroblast cells using comet assay for the first time. Materials and Methods: Fibroblast cells were pretreated 15 and 30 min with concentrations of 100, 200 and 300 μg/mL EETP then they were exposed to 3 Gy γ-rays. Amifostine (synthetic aminothiol compound) was used as a positive control. Results: The results showed a significant decrease in γ-ray-induced DNA damage on cells treated with EETP and amifostine when compared to only irradiated cells. (P < 001). Conclusion: It was concluded that EETP prevent γ-ray-induced DNA damage in fibroblast cells and might have radioprotective activity.
AtıfScopus20WoS24OpenAlex25İncele - MakaleYalnız künye2016Scopus SJRQ2Simplified Early Stopping Criterion for Belief-Propagation Polar Code Decoders
Simsek, Cemaleddin; Turk, Kadir
As the first theoretically proven capacity-achieving error correction code, polar codes have become a milestone in information theory field, which draw serious attention by its low complexity encoding and decoding structures. For the decoding section, studies are focused on efficient and low complex algorithms based on successive cancellation and belief-propagation (BP) decoders. To reduce computational complexity of BP-based decoders further, early stopping methods that avoid unnecessary iterations can be used. In this letter, we propose a reduced complexity early stopping method for BP-based polar code decoders. The proposed method is based on the hypothesis that observing only a small cluster of information bits polarized to the highest error probabilities is enough to detect successful decoding. Simulation results show that the proposed early stopping criterion significantly reduces the computational complexity of successful decoding detection as well as the total operation numbers of the whole decoding process compared with previous methods in the literature.
AtıfScopus45WoS41OpenAlex47İncele - MakaleYalnız künye2016Scopus SJRQ1Logistics center site selection by ANP/BOCR analysis: A case study of Turkey
Peker, Iskender; Baki, Birdogan; Tanyas, Mehmet; Murat Ar, Ilker
Site selection for logistics centers is one of the most strategic decisions in logistics. This study addresses the problem of logistics center site selection, using Analytic Network Process/Benefits, Opportunities, Costs and Risks, which is a multi-criteria decision making technique. The decision problem is applied to the city of Trabzon, which is an important city of the Eastern Black Sea Region in Turkey. First, the results are evaluated in terms of each sub-network and each group and, next, are consolidated for each alternative. They yield that Alternative A is the most appropriate logistics center location of all in Trabzon. Furthermore, the sensitivity analysis results emphasize that the decision model is robust.
AtıfScopus40WoS34OpenAlex45İncele - MakaleAçık Erişim2016Scopus SJRQ2Kinetic and in silico studies of hydroxy-based inhibitors of carbonic anhydrase isoforms I and II
Ekhteiari Salmas, Ramin; Mestanoglu, Mert; Durdagi, Serdar; Sentürk, Murat; Kaya, A. Afşin; Kaya, Elif Çelenk
A series of hydroxy and phenolic compounds have been assayed for the inhibition of two physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isozymes, the cytosolic human isozymes I and II. The investigated molecules showed inhibition constants in the range of 1.07-4003 and 0.09-31.5 μM at the hCA I and hCA II enzymes, respectively. In order to investigate the binding mechanisms of these inhibitors, in silico studies were also applied. Molecular docking scores of the studied compounds are compared using three different scoring algorithms, namely Glide/SP, Glide/XP and Glide/IFD. In addition, different ADME (absorption, distribution, metabolism and excretion) analysis was performed. All the examined compounds were found within the acceptable range of pharmacokinetic profiles.
AtıfScopus10WoS11OpenAlex15İncele - MakaleYalnız künye2016Scopus SJRQ1Subduction-related Late Carboniferous to Early Permian Magmatism in the Eastern Pontides, the Camlik and Casurluk plutons: Insights from geochemistry, whole-rock Sr–Nd and in situ zircon Lu–Hf isotopes, and U–Pb geochronology
Karsli, Orhan; Dokuz, Abdurrahman; Kandemir, Raif
Late Carboniferous to early Permian granitoid rocks represent a volumetrically minor component of the Eastern Pontide lithosphere, but they preserve useful information about the region's tectonomagmatic history. The Casurluk and Camlik plutons primarily consist of gabbro, gabbroic diorite, diorite, monzogabbro, monzodiorite and monzonite, which intrude early to middle Carboniferous granitic basement rocks in the region. In this study, we use in situ zircon U–Pb ages and Lu–Hf isotopic values, whole-rock Sr–Nd isotopic values, and mineral chemistry and geochemistry of these plutons to determine petrogenesis and crustal evolution; we also discuss geodynamic implications. LA–ICP-MS zircon U–Pb dating of magmatic zircons from the rocks suggests that the plutons were emplaced during the late Carboniferous to early Permian (302 Ma). The metaluminous and I-type intrusive rocks belong to the high-K calc-alkaline series. In addition, they are relatively enriched in light rare earth elements (LREEs) and large-ion lithophile elements (LILEs); they are depleted in heavy rare earth elements (HREEs) and high field strength elements (HFSEs), such as Nb and Ti. All of the samples have homogeneous initial ISr values (0.70675 to 0.70792) and low εNd (t) values (− 5.1 to − 3.3). Zircons from the rocks of both plutons have uniform negative to slightly positive εHf (t) values (− 3.5 to 1.4) and old Hf two-stage model ages (1323 to 1548 Ma), implying that they have the same source, as well as suggesting the involvement of old enriched lithospheric mantle materials during their magma genesis. These results, combined with the εHf (t) values and two-stage model ages, demonstrate that the primary magmas were derived from partial melting of old lithospheric mantle material metasomatized by subduction-related fluids. Considering other regional geological data from the Sakarya Zone where these plutons formed, we conclude that late Carboniferous to early Permian magmatism in the area involved the partial melting of a phlogopite- and spinel-bearing lherzolite under an extensional regime in a subduction-related setting. Such an extension event would have caused hot asthenospheric upwelling and was likely triggered by back-arc rifting during subduction of the Paleo-Tethyan oceanic slab. Thus, the magmas are likely subduction-related products, implying that southward subduction of Paleo-Tethys oceanic lithosphere in the region began during the late Carboniferous to early Permian.
AtıfScopus59WoS55OpenAlex65İncele - MakaleAçık Erişim2016Scopus SJRQ2Kinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation
Saral, Aysegul; Leonard, David A; Duzgun, Azer Ozad; Cicek, Aysegul Copur; June, Cynthia M; Sandalli, Cemal
The class A β-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a structure that is known to have major effects on substrate selectivity in class A β-lactamases, we expressed, purified and kinetically characterized this novel variant. Our results show that compared with GES-116×His, GES-226×His displays more efficient hydrolysis of penicillins, and aztreonam, but a loss of efficiency against ceftazidime. In addition, the M169L substitution confers on GES-22 more efficient hydrolysis of the mechanistic inhibitors clavulanic acid and sulbactam. These effects are highly similar to other mutations at the homologous position in other class A β-lactamases, suggesting that this methionine has a key structural role in aligning active site residues and in substrate selectivity across the class.
AtıfScopus5WoS4OpenAlex5İncele - MakaleAçık Erişim2016Scopus SJRQ2Determining the Effect of Seasonal Variation in Spruce (Picea orientalis L.) Wood Treated with Various Impregnations on Combustion Resistance
Yasar, Ş. Şadiye; Fidan, M. Said; Yaşar, Mehmet; Atar, Musa; Alkan, Elif
Prepared test specimens were surface treated and coated with synthetic and water-based outdoor varnishes after being chemically impregnated. The test specimens were left outdoors to determine the effects of impregnation and treatment on the wood during each of the four seasons. Caucasian spruce (Picea orientalis L.) test specimens were prepared and combustion analyses were performed. As a result of the combustion test, weight loss results, as compared with the control, were 89% lower in the spring specimens, 90% lower with impregnation, and 90% lower with the synthetic varnish coating. Furthermore, the O2 amount during combustion was found to be the highest in combustion with a flame source in the winter specimens (21%). The CO2 amount was the highest in combustion without a flame source for full-year specimens (20%). The CO amount was the highest in combustion without a flame source of full-year specimens (31,787 ppm), and the NO amount was the highest during glowing of full-year specimens (55 ppm). Final results showed impregnation with Tanalith-E and water-based varnish coating to be the most effective fire protective treatments.
AtıfScopus5WoS5OpenAlex3İncele - MakaleYalnız künye2016Scopus SJRQ2Influence of CrN Coating on Electrochemical Behavior of Plasma Nitrided Pure Titanium in Bio-simulated Environment
Çelik, Ilhan
Titanium and its alloys are widely used as materials for bio-medical applications, such as implants. However, ions of the alloy can release to the body region and spread into the blood circulation. In this study, plasma nitriding and CrN coating techniques are used in order to overcome the problem of ion release. The objective of this study was to investigate the effects of plasma nitrided pure titanium on the structural properties and corrosion behaviors before and after CrN coating in Ringer's solution at 37 °C. The structural properties were investigated using Scanning Electron Microscopy (SEM) and X-ray diffraction (XRD). A diffusion layer and a compound layer composed of δ-TiN and ε-Ti2N phases were observed on the surface of nitrided pure titanium. Corrosion tests were made for the determination of electrochemical properties with the help of Potentiostat/Galvanostat device. The results show that corrosion behaviors of untreated and treated samples have similar characteristic.
AtıfScopus19WoS15OpenAlex19İncele - MakaleAçık Erişim2016Scopus SJRQ3Investigation of structural and tribological properties of duplex surface treated pure titanium
Çelik, I.; Karakan, M.
Commercial pure titanium (CP-Ti) is used in many engineering fields because of its superior properties such as excellent corrosion resistance, high strength/weight ratio, and biocompatibility. However, it is not available at the desired rate, since the CP-Ti has poor wear resistance. For this reason, many surface treatments have been applied to improve the poor tribological properties of the CP-Ti. In this study, duplex surface treatments, which are the combination of treatments of electroless Ni-B coating and plasma nitriding, were applied on the surfaces of the CP-Ti. Structural properties of the different surfaces of the treated materials were investigated using scanning electron microscopy (SEM) and X-ray diffraction (XRD). Microhardness measurements were made for the determination of mechanical properties and the pin-on-disk wear tests were made to determine the tribological properties. It was observed that poor wear resistance of the CP-Ti was improved with duplex surface treatments. The results showed that surface hardness, friction coefficient, and surface roughness of coated samples were better than of uncoated CP-Ti.
AtıfScopus7WoS5OpenAlex6İncele - MakaleAçık Erişim2016Scopus SJRQ3Determination of stand structure in even-aged oriental beech forests in Turkey; [Determinación de la estructura de rodales de Fagus orientalis coetáneos en Turquía]
Kahriman, Aydın; Altun, Lokman; Güvendi, Engin
This study aimed at developing a stand yield model for even-aged and pure Oriental beech (Fagus orientalis) stands in Sinop Province, located in the north of Turkey. The data used in this study were obtained from 238 sample plots. The sample plots are 24–131 years of stand age range, 19.0–35.9 m of site index range, and 2.2–10.8 of stand density range (relative density index). With the generated equation systems, stand age, site index and density of the three main factors in Oriental beech stands, including the effects of individual, dual and triple factor interactions on the stands were numerically determined. As for even-aged Oriental beech stands, the main stand volume values increase depending on age, site index and density. The number of stems per hectare decreases as the stand grows older, and site index rises; the number, however, increases in parallel with stand density. The current annual volume increment reaches a peak at 30-35 years at all site index groups and density levels, and begins to fall afterwards. Mean annual volume increment peaks up at 65-75 years at all site index classes and density levels, before beginning to decline. The results were in arrangement with the acknowledged growth rules. Stand yield models were assessed as Density-Variable Yield Table used for estimation of the remaining, removal and total stands.
AtıfScopus4WoS3OpenAlex1İncele - MakaleAçık Erişim2016Scopus SJRQ2Diversity and ecology of benthic algae in Karagöl Lake, Karagöl-Sahara National Park (Şavşat, Artvin, Turkey)
Akar, Bülent; Şahın, Bülent
Benthic algal flora of Karagöl Lake, its seasonal variation, and the physical and chemical parameters of the water were studied between October 2008 and September 2010. The algal flora consisted of 112 taxa belonging to the divisions Charophyta (41), Chlorophyta (33), Cyanobacteria (18), Euglenozoa (17), Miozoa (2), and Ochrophyta (1). Six desmid taxa found in this research are new records for the freshwater algal flora of Turkey. The qualitative dominance of benthic taxa typical of slightly alkaline and mesotrophic ecosystems was observed. The qualitative and seasonal variations in epipelic taxa analyzed were dependent on the physicochemical characteristics of the water. Water quality was analyzed on the basis of benthic taxa, which are bioindicators. The physicochemical properties of the water are suitable for the development of a rich algal flora (especially desmids). According to the benthic algal composition and indicator species, it is estimated that Karagöl Lake has mesotrophic lake characteristics. This is the first study of benthic algal flora of Karagöl Lake and marks a significant contribution to the knowledge of Karagöl-Sahara National Park’s aquatic biodiversity.
AtıfScopus5WoS3OpenAlex3TR Dizin1
İncele - MakaleAçık Erişim2016Scopus SJRQ3Existence and uniqueness theorems for sequential linear conformable fractional differential equations
Gökdoğan, Ahmet; Ünal, Emrah; Çelik, Ercan
Recently, a new definition of fractional derivative called as the conformable fractional derivative which based on limits introduced by Khalil et al (2014). Later, Abdeljawad (2015) improved these definitions and gave the basic concepts in this new fractional calculus. In this paper, we generalize Abel's formula and Wronskian determinant definition and establish existence and uniqueness theorems for sequential linear conformable fractional differential equations.
AtıfScopus27WoS26OpenAlex40İncele - MakaleYalnız künye2016Scopus SJRQ1U–Pb zircon chronology and petrogenesis of Carboniferous plutons in the northern part of the Eastern Pontides, NE Turkey: Constraints for Paleozoic magmatism and geodynamic evolution
Kaygusuz, Abdullah; Arslan, Mehmet; Sipahi, Ferkan; Temizel, İrfan
Numerous intrusive rocks of varying ages and compositions exist in the Paleozoic to Tertiary periods in the Eastern Pontides. Carboniferous intrusive rocks are commonly observed in the southern part of the Eastern Pontides. The nature of the rocks in the northern part of the region has not been determined because of Upper Cretaceous and Tertiary volcano-sedimentary units. Whole-rock geochemical, isotopic and geochronological data obtained from five different mapped granitoid bodies located in the northern part of the Eastern Pontides allow for the proper reconstruction of Carboniferous magmatism and the geodynamic evolution of the region. According to laser ablation ICP-MS U–Pb zircon dating, the Özdil, Soğuksu, Seslikaya, Kızılağaç and Şahmetlik plutons have similar 206Pb/238U vs. 207Pb/235U concordia ages of 340.7 ± 1.8 Ma and 323.1 ± 1.5 Ma, 348.4 ± 1.6 Ma, 335.4 ± 1.4 Ma, 337.2 ± 0.6 Ma and 334.5 ± 1.4 Ma, respectively. The aluminium saturation index (ASI) values of all of the samples from the plutons are between 1.0 and 1.32, which indicate peraluminous melt compositions. The plutons have SiO2 contents between 59 and 79 wt.% and show low- to high-K calc-alkaline characteristics. The plutons are enriched in large-ion lithophile and light rare earth elements and are depleted in high-field strength elements. Chondrite-normalized rare earth element patterns are characterized by concave-upward shapes and pronounced negative Eu anomalies, with LaCN/YbCN = 1.9–46.8 and EuCN/Eu* = 0.19–1.76. The studied plutons show considerable variations in 87Sr/86Sr(i) (0.70255 to 0.71006) and εNd(i) values (− 4.8 to − 7.1), as well as Nd model ages (1.15 to 2.47 Ga). The Pb-isotopic ratios are 206Pb/204Pb = 17.11–18.60, 207Pb/204Pb = 15.58–15.64 and 208Pb/204Pb = 36.95–38.62. The crystallization temperatures of the melts range from 676 to 993 °C, as determined by zircon and apatite saturation thermometry. These data suggest that the Carboniferous granitic magmas were produced by the partial melting of meta-mafic to meta-felsic lower crustal source rocks, with minor contributions from the mantle. Collectively, these rocks represent a late stage of Hercynian magmatism in the northern part of the Eastern Pontides.
AtıfScopus90WoS84OpenAlex97İncele - MakaleYayıncıda açık erişim2016Scopus SJRQ1Modeling deformation modulus of a stratified sedimentary rock mass using neural network, fuzzy inference and genetic programming
Alemdag, S.; Gurocak, Z.; Cevik, A.; Cabalar, A.F.; Gokceoglu, C.
This paper investigates a series of experimental results and numerical simulations employed to estimate the deformation modulus of a stratified rock mass. The deformation modulus of rock mass has a significant importance for some applications in engineering geology and geotechnical projects including foundation, slope, and tunnel designs. Deformation modulus of a rock mass can be determined using large scale in-situ tests. This large scale sophisticated in-situ testing equipments are sometimes difficult to install, plus time consuming to be employed in the field. Therefore, this study aims to estimate indirectly the deformation modulus values via empirical methods such as the neural network, neuro fuzzy and genetic programming approaches. A series of analyses have been developed for correlating various relationships between the deformation modulus of rock mass, rock mass rating, rock quality designation, uniaxial compressive strength, and elasticity modulus of intact rock parameters. The performance capacities of proposed models are assessed and found as quite satisfactory. At the completion of a comparative study on the accuracy of models, in the results, it is seen that overall genetic programming models yielded more precise results than neural network and neuro fuzzy models.
AtıfScopus113WoS110OpenAlex108İncele - MakaleYalnız künye2016Scopus SJRQ3Students understanding of mathematics using from prototypical examples: Analyze in linear algebra
Aydin, Sinan; Akkan, Yaşar
Mathematical objects are ʼnatural objects’ for the practical mind. Definitions and theories can only describe them, not create or construct them. A mathematical term is interpreted through its denotation as representing a collection of particular objects for the theoretical mind. So, theoretical and practical modes of thinking differ in the manner in which they constitute the meanings of words. Thinking in terms of prototypical examples, rather than definitions, became an obstacle to our students’ understanding the notion of linear transformation. In the course, linear transformations were defined as transformations of vector spaces which conserve linear combinations. The obstacle was revealed in the students’ attempts ‘linear extension problem’: given a transformation of a basis, to construct a linear transformation with those values on the basis. In the experimental course, the problem was not formulated in such general terms. It was restricted to two dimensions, and the students were not asked to ‘linearly extend a transformation from a basis to the whole plane’ but to assume the existence of such an extension and find some missing information about it. In this study we are discussing students understanding of mathematical concepts by means of linear transformation in linear algebra.
- MakaleAçık Erişim2016Scopus SJRQ2Effect of Turkish pollen and propolis extracts on caspase-3 activity in myeloid cancer cell lines
Uçar, Meltem; Değer, Orhan; Gerigelmez, Asuman Yiğit; Cengiz, Sevil; Barlak, Yaşam; Ovalı, Ercüment
Purpose: To investigate the apoptosis-inducing capacity of dimethyl sulfoxide (DMSO) extracts of bee pollen and propolis in HL-60 Myeloid Cancer Cell Lines. Methods: DMSO extracts of pollen and propolis were incubated separately with HL-60 cells, and caspase-3 activity evaluated. In order to determine the cell cycle characteristics of HL-60 cells with and without extracts of pollen and propolis, the cells were analysed using flow cytometry. Results: The DMSO extract of propolis (0.5 mg/mL) increased apoptosis from undetectable levels to 60.1%, while maintaining cell viability. The DMSO extract of pollen (2 mg/ml) increased apoptosis from undetectable levels to 52.2% while decreasing cell viability by 62%. Caspase-3 activity in HL-60 cells incubated with DMSO extracts of pollen and propolis were 3.6-to 12-fold higher than in controls. Conclusion: Turkish pollen and propolis individually increase apoptosis and the activity of caspase-3 in HL-60 cells. This finding indicates that bee products may have beneficial effects in the treatment of cancer.
AtıfScopus12WoS10OpenAlex12İncele - MakaleYalnız künye2016Scopus SJRQ3Determination of Pomological and Morphological Characteristics and Chemical Compositions of Local Apple Varieties Grown in Gumushane, Turkey; [Bestimmung der pomologischen und morphologischen Eigenschaften sowie der chemischen Zusammensetzung lokaler Apfelsorten aus dem Gebiet Gumushane, Türkei]
Kalkisim, Ozgun; Ozdes, Duygu; Okcu, Zuhal; Karabulut, Besim; Senturk, Hasan Basri
The present study was conducted in order to determine the pomological and morphological characteristics and chemical compositions of some local apple varieties grown in Gumushane. As a result of field work in Gumushane province, sixteen different apples, which are Summer Apple, English apple, Green Belly, Black Belly and Yellow Belly Apples, Amasya Marble, Bey Apple, Chest Apple, Mahsusa, Arabian Girl, Willow Apple, Tavşanbaşı, Yellow Hıdır, Local Marble, Bride Apple, and Fatty Apple were collected in order to analyze. The average results of pomological and morphological properties and chemical compositions were obtained as following: fruit mass; 127.36 g, fruit width; 65.23 mm, fruit length; 57.30 mm, fruit stalk thickness; 2.17 mm, fruit stalk length; 17.63 mm, stalk pit depth; 12.75 mm, flower pit depth; 10.29 mm, fruit firmness; 13.79 kg/cm2, seed house width; 15.89 mm, seed house length; 17.39 mm, number of seeds; 4.3, water soluble dry matter content; 14.53 %, ash content; 1.11 %, pH; 3.8, titratable acidity; 0.69 g/L, water content; 83.8 %, reducing sugar; 5.04 g/100 g, sucrose; 2.25 g/100 g, and the amount of total sugars; 7.29 g/100. The fruit peel color was determined by considering the light transmittance (L). The average L values were ranged between 112.06 and 66.32. On the other hand among the mineral elements, potassium and manganese amounts were determined as the highest and the lowest, respectively.
AtıfScopus13WoS10OpenAlex13İncele