Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(87)
- Merdan, Mehmet(70)
- Duran, Celal(56)
- Baltaci, Cemalettin(52)
- Kulakaç, Nurşen(51)
- Ozdes, Duygu(51)
- Kaygusuz, Abdullah(47)
- Öztürk, Serkan(42)
- Demir, Selim(40)
- Karsli, Orhan(37)
- Turan, Ibrahim(37)
- Dokuz, Abdurrahman(36)
- Gücer, Mehmet Ali(36)
- Sipahi, Ferkan(36)
- Araz, Onur(35)
- Kandemir, Raif(31)
- Vural, Alaaddin(31)
- Topal, Fevzi(30)
- Kurt, Kemal(29)
- Ürkek, Bayram(29)
- Maden, Nafiz(28)
- Acet, Tuba(27)
- Alemdag, Selcuk(26)
- Arslan, Mehmet(26)
- Ayaydin, Hasan(26)
- Akaryali, Enver(25)
- Aydin, Faruk(25)
- Baltacı, Cemalettin(25)
- Yücel, Cem(25)
- Akar, Zeynep(24)
- Barut, Abdulkadir(24)
- Ozturk, Samet(24)
- Pala, Fahrettin(24)
- Peker, Iskender(24)
- Topal, Meryem(24)
- Yildiz, Salih(24)
- Öz, Mehmet(24)
- Aliyazicioglu, Yuksel(23)
- Bostan, Sedat(23)
- Kankal, Murat(23)
Yayınlar
- MakaleYalnız künye2026Scopus SJRQ1Radio frequency heating of whole peanuts for microbial safety and quality preservation using interlayer displacement under stationary and moving conditions: Effects of salt coating and natural skin on heating behavior
Kahraman, Kubra; Tasci, Caner; Cakir, Elif Nida; Liu, Shuxiang; Soncu, Eda Demirok; Erdogdu, Ferruh; Ozturk, Samet
This study aimed to improve the efficiency of a radio frequency (RF) heating system for pasteurizing whole peanuts while maintaining quality attributes using a stationary position or continuous movement. Heating efficiency was evaluated using commercially available roasted whole peanuts: salt-coated skin-on, unsalted skin-on, and unsalted peeled peanuts. To improve heating uniformity and ensure sufficient microbial inactivation of Salmonella enterica serovar Enteritidis PT30, a single interlayer-displacement strategy was applied in both stationary and continuous modes. Quality attributes including protein structure and fatty-acid profiles were assessed under the selected RF processing conditions. The RF system equipped with a conveyor belt was used to process peeled, unsalted peanuts inoculated with S. Enteritidis PT30 at approximately 7.9–8.5 log CFU/g. The three commercial peanut types exhibited differences in RF temperature distribution and heating uniformity, with salt-coated skin-on peanuts showing higher average temperature than unsalted peeled samples under the evaluated conditions. Continuous movement increased average temperature by approximately 10 °C but resulted in poorer heating uniformity, with a 3 °C higher standard deviation (SD). A single interlayer-displacement (overturning) step improved heating uniformity. This step increased Salmonella reductions from 3.41 to 4.77 log CFU/g under stationary processing and from 2.92 to 4.22 log CFU/g under continuous processing after 60 min of RF heating. The evaluated protein and lipid quality characteristics of unsalted peeled peanuts remained largely unchanged following RF processing. Overall, these findings demonstrated the potential of RF heating combined with interlayer displacement for microbial decontamination of unsalted peeled whole peanuts while maintaining the quality attributes evaluated in this study.
- MakaleYalnız künye2026Scopus SJRQ2Radiation shielding performance and microstructural characterization of Al–Cu-Sc/B4C nanocomposites
Şirin, Murat; Kaya, Selim; Temiz, Cengiz; Çağlar, Seyit
This study investigates the gamma-ray and fast-neutron shielding performance of Al–Cu–Sc/B4C nanocomposites containing 0–20 wt% boron carbide (B4C). The composites were produced using melt spinning, high-energy ball milling, and vacuum sintering techniques. Their structural and microstructural characteristics were examined by X-ray diffraction and scanning electron microscopy. Gamma-ray attenuation properties were measured experimentally at photon energies of 0.662, 1.173, and 1.333 MeV using a high-purity germanium detector. In addition, theoretical calculations were carried out in the 0.05–2.50 MeV energy range using Monte Carlo simulations together with the Phy-X/PSD calculation platform. Several radiation shielding parameters were evaluated, including the mass attenuation coefficient, half-value layer, mean free path, radiation protection efficiency, effective atomic number, and fast-neutron removal cross-section. The results show that the incorporation of B4C improves the fast-neutron shielding capability of the composites. The sample containing 20 wt% B4C exhibits an increase of approximately 32% in fast-neutron removal cross-section compared with the reference alloy. A slight reduction in gamma-ray attenuation is observed at low photon energy, whereas the shielding performance at medium and high energies remains nearly unchanged. These findings indicate that Al–Cu–Sc/B4C nanocomposites are promising lightweight and lead-free candidates for shielding against mixed gamma and neutron radiation. Their low density and the absence of toxic lead support potential applications in medical radiation facilities, nuclear technology systems, aerospace platforms, and industrial radiation environments where both radiation protection and weight reduction are important.
AtıfScopus7WoS7OpenAlex6
İncele - MakaleYalnız künye2026Scopus SJRQ1Blue-Shift Effect-Based Positioning for Multi-Color VLC
Kucuk, Mehmet Ali; Turk, Kadir
In this letter, an angle-of-arrival (AoA)-based integrated positioning system is proposed that utilizes the standard optical front-end of multi-color visible light communication (MC-VLC). Unlike traditional AoA methods, which rely on specialized receiver architectures, the proposed approach uses the inherent angular dependence of optical filter transmission responses, known as the blue-shift effect, for directly estimating the angle of incidence from the received signal. In this context, an AoA estimation technique is developed by combining eigenvalue decomposition of the MC-VLC channel with regression analysis. Simulation results show that the proposed system achieves millimeter-level positioning accuracy, enabling robust and high-precision indoor localization without additional hardware complexity or cost.
AtıfScopus2OpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ1When grief persists online: Development of the Digital Prolonged Grief Severity Scale
Çınar, Öznur; Cengiz, Ekrem
Bereaved individuals encounter the deceased through social media profiles, message histories, and algorithmic reminders, yet no validated instrument measures prolonged grief expressed through digital interactions. We developed and validated a multidimensional measure of digital-environment prolonged grief severity (DPGSS). Turkish bereaved adults (n = 577) bereaved at least 12 months earlier completed the DPGSS alongside grief, distress, and other less relevant measures, and 125 completed it again about three weeks later. Factor analyses supported a four-factor structure—digital separation distress and preoccupation, digital emotional responses, digital avoidance, and digital functional impairment—in 15 items. The correlated four-factor model fit the data well, outperforming a one-factor alternative. The DPGSS demonstrated strong internal consistency, test-retest reliability, and measurement invariance across nine demographic variables. Convergent associations with grief and distress, and negligible associations with rigidity and AI acceptance, supported its construct specificity. The DPGSS-15 is a reasonable tool for assessing digital prolonged grief.
- MakaleAçık Erişim2026Scopus SJRQ1Semi-experimental approach for hydrogen storage of as-produced zeolitic imidazolate framework-8 without post-processing
Öztürk, Banu; Asan, Abdurrahman; Köse, Dursun Ali; Kalkişim, Ahmet Tahir; Öztürk, Zeynel
Low-cost hydrogen storage systems are essential for the widespread use of hydrogen, particularly in mobile platforms such as unmanned aerial vehicles, to increase their range. Hydrogen storage in metal–organic frameworks (MOFs), which offer high capacity through adsorption, is crucial to achieving this goal. This study investigates the hydrogen storage capacity of zeolitic imidazolate framework-8 (ZIF-8), produced via reactive extrusion, which allows for high production capacity and low-cost manufacturing of MOFs. Furthermore, particular attention was given to the storage capacity of ZIF-8 in its as-produced form. An atomistic model of the as-produced ZIF-8, including impurities selected from a series of simulated models containing different amounts of impurity, was developed. The validity of the selected structure was then verified through experimental powder X-ray diffraction and Brunauer–Emmett–Teller (BET) surface area measurements. Subsequently, hydrogen adsorption capacities for varying pressures and temperatures were calculated. The hydrogen adsorption simulations indicated that the atomistic model of the as-produced ZIF-8 exhibited a hydrogen storage capacity of 1.76 wt.% at 77 K and 1 bar, corresponding to a BET surface area of 516 m2/g. In comparison, the experimentally synthesized as-produced ZIF-8 showed a capacity of 1.145 wt.% under the same conditions, with a BET surface area of 520 m2/g. The study demonstrates that the gas storage performance of experimentally produced structures, even without further purification, can be accurately determined through simulation models in this semi-experimental study.
- MakaleAçık Erişim2026Scopus SJRQ4Assessment of the effect of conventional and contemporary drying methods on the phenolic profile modulation and antioxidant retention of Trabzon persimmon (Diospyros kaki L.)
Koçak, Tevfik; Demirel Ozbek, Yagmur; Saral, Ozlem; Kocyigit, Emine
This study investigated the effects of conventional and modern drying methods on the total phenolic content, antioxidant activity, and phenolic compound composition of Trabzon persimmons (Diospyros kaki L.) fruits harvested from the same tree and at comparable maturity stages were subjected to sun drying, shade drying, oven drying, air-fryer drying, and microwave drying techniques, with raw samples serving as the control group. The total phenolic content was assessed via the Folin–Ciocalteu method, and the antioxidant capacity was evaluated using the ferric reducing antioxidant power (FRAP) and DPPH radical scavenging activity assays. The identification and quantification of phenolic compounds were conducted using the HPLC technique. The results indicated that the drying process produced statistically significant variations in the phenolic content and antioxidant capacity of Trabzon persimmons. The microwave drying technique resulted in highest total phenolic content and antioxidant activity, whereas both sun and shade drying procedures showed higher values than raw samples. The total phenolic content and antioxidant capacity of samples dried in an air fryer were found to be comparable to those of raw samples. The profile of phenolic compounds varied according to the drying process employed; certain compounds exhibited an increase with specific methods, while others were identified solely under particular conditions. Thus, it has been shown that drying techniques can have a significant impact on preserving and improving the functional properties of persimmons. Furthermore, we believe that microwave drying could be an effective alternative, particularly in terms of preserving bioactive compounds.
AtıfScopus1OpenAlex1
İncele - MakaleYalnız künye2026Scopus SJRQ1A logarithmic-type estimator for finite population variance and its efficiency properties
Iftikhar, Soofia; Alamgir; Zaman, Tolga
This study proposes a novel logarithmic-type estimator for the finite population variance. We derive the mean square error (MSE) expressions, approximated to the first order, along with the associated efficiency conditions for the proposed estimator, as well as for several existing estimators from the literature. A comprehensive simulation study is conducted to compare the efficiency of the new estimator against these established methods. Based on the analysis of a real dataset, the results demonstrate that the proposed estimator achieves the minimum mean square error and satisfies all relevant efficiency criteria. Consequently, it is concluded that the proposed estimator outperforms the other considered estimators in terms of efficiency.
- MakaleYayıncıda açık erişim2026Scopus SJRQ4A data-driven decision-support framework for prioritizing retention interventions among high attrition-risk employee segments
Şimşek, Tuğçe; Şimşek, Aybala
Predicting employee attrition risk provides a useful signal for human resource decision-making. However, this signal alone does not determine which employee groups should be targeted first for retention interventions. This study develops a data-driven decision-support framework for prioritizing retention interventions among employees at risk of attrition. The framework uses the IBM HR Analytics Employee Attrition and Performance dataset and integrates calibrated machine learning, SHAP-based explanatory analysis, Entropy-CRITIC weighting, and PROMETHEE II ranking. Machine-learning models were first used to estimate employee-level attrition probabilities. These probabilities were then aggregated into segments defined by combinations of Department, JobRole, and OverTime, from which the high-risk segment pool was identified for multi-criteria analysis. Eight high-risk segments were detected. The segment ranked first by PROMETHEE II was not the segment with the highest attrition risk, indicating that intervention priority and attrition risk represent distinct decision outputs. Sensitivity analyses further showed that the segment-ranking structure remained stable under alternative weight-shift and threshold scenarios. The proposed framework is therefore not intended to identify individual employees at risk; rather, it supports transparent, auditable, and ethically compliant segment-level retention decisions.
- MakaleYalnız künye2026Scopus SJRQ1A multi-scale context-aware deep learning framework for medical disease diagnosis
Reis, Hatice Catal; Turk, Veysel
Early and accurate diagnosis of brain tumors, skin lesions, and diabetic retinopathy is essential for effective treatment planning and improving patient prognosis. Nevertheless, the diagnostic process for these conditions remains challenging due to the reliance on conventional methods, which are often subjective, time-intensive, and dependent on expert interpretation. In this context, deep learning-based approaches offer promising opportunities to enhance diagnostic precision and support clinical decision-making. This study introduces BSCRADNet, a novel deep learning model designed for the automated diagnosis of oncological and retinopathic diseases. The proposed architecture employs a multi-layered analytical framework that integrates local and spatial features with long-range contextual dependencies, enabling the effective recognition of complex morphological patterns in medical images. By enhancing diagnostic consistency, BSCRADNet reduces the risk of misclassification—particularly in cases characterized by high inter-observer variability or subtle lesion presentation. The model demonstrated strong performance across multiple datasets, achieving classification accuracies of 94.67% for brain tumors, 89.58% for skin cancer, and 90.40% for diabetic retinopathy. Furthermore, to improve the discriminative power of feature representations across diverse disease categories, a composite hybrid architecture combining BSCRADNet with ResMLP was developed. This hybrid model yielded competitive results, with accuracies of 93.33%, 88.19%, and 87.40% for the respective diagnostic tasks. Experimental findings indicate that the proposed approach is capable of distinguishing intricate patterns in medical imaging data and holds significant potential for integration into clinical diagnostic workflows, contributing to more reliable and efficient disease classification.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2026Scopus SJRQ3New and noteworthy liverwort records for Türkiye and South-West Asia
Erata, Hüseyin; Batan, Nevzat; Mamontov, Yuriy S.; Özdemir, Turan
The liverwort taxa Cephaloziella elegans and Mesoptychia gillmanii are reported for the first time from Türkiye and Southwest Asia, based on a bryological field trip to the Karçal Mountains in the Caucasian region (Artvin). Additionally, Lophoziopsis excisa is recorded for the second time in Türkiye, with the newly discovered locality extending the known national distributions of this taxon. Descriptions, illustrations, data on world distribution and ecology, as well as comparisons with morphologically similar species, are provided.
AtıfOpenAlex4İncele - MakaleYalnız künye2026Scopus SJRQ1Nutritional value, heavy metal contamination and health risk assessment of Phalangium opilio Linnaeus, 1758 as a potential edible arachnid
Gürmeriç, Hüseyin Ender; Kurt, Pınar; Ürkek, Bayram
Edible insects and arachnids have increasingly been recognised as alternative food sources. The aim of the study was to evaluate the harvestman species Phalangium opilio (P. opilio) Linnaeus, 1758 as a new edible species. In this research, some chemical properties, fatty acid and mineral composition of the P. opilio were investigated. Additionally, the heavy metal contamination and its health risk assessment were evaluated. The fat and protein contents of the samples were 1.18% and 14.07%, respectively. The P. opilio had unsaturated fatty acids such as myristoleic, palmitoleic, linoleic and oleic acids. The P. opilio was analyzed for K, Mg, Na, Ca, Fe, Zn, Al, Mn, Se contents, estimated daily intake and contributions to the recommended daily mineral intake were calculated. The heavy metals detected in the P. opilio were Cu, Ni, Cd, Pb, As, Cr, Co and Ag. The Cd had the highest target hazard quotient value (2.16). The hazard index value of the P. opilio was 3.32 and it had a potential health risk level. Consequently, although P. opilio exhibited favourable nutritional properties, the THQ value for Cd and the cumulative HI value exceeded the recommended safety threshold, indicating a potential non-carcinogenic health risk associated with its consumption. Accordingly, considering the detected heavy metal levels and associated health risk indices, the consumption of wild-collected P. opilio should be approached with caution. © Hüseyin Ender Gürmeriç et al., 2026. Published with license by Koninklijke Brill BV. This work is published by Koninklijke Brill BV. Koninklijke Brill bv incorporates the imprints Brill, Brill Nijhoff, Brill Schöningh, Brill Fink, Brill mentis, Brill Wageningen Academic, Vandenhoeck & Ruprecht, Böhlau and V&R unipress. Koninklijke Brill BV reserves the right to protect the publication against unauthorized use and to authorize dissemination by means of offprints, legitimate photocopies, microform editions, reprints, translations, and secondary information sources, such as abstracting and indexing services including databases. Requests for commercial re-use, use of parts of the publication, and/or translations must be addressed to Koninklijke Brill BV.
- MakaleYalnız künye2026Scopus SJRQ2Novel 1,2,4-triazole-based n-mannich derivatives: Synthesis, spectroscopic characterization, cytotoxic, antimicrobial, and enzyme inhibitory activities, and in silico studies
Yılmaz, Yonca; Medetalibeyoğlu, Hilal; Kapancık, Serkan; Tüzün, Burak; Lukšič, Miha; Aslan, Rukiye; Topal, Fevzi; Kocyigit, Umit M.; Yüksek, Haydar; Harmankaya, Ahmet
A series of novel 1,2,4-triazole-based Mannich bases was designed, synthesized, and evaluated for biological and theoretical properties. Schiff base intermediates (C1–6) were prepared by condensing 4-benzoxy-3-methoxybenzaldehyde with various 3-substituted-4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones. Mannich reactions with formaldehyde and 2,6-dimethylmorpholine produced six target compounds (D1–6). Structures were confirmed using spectroscopic techniques. Following structural confirmation, the compounds showed significant cytotoxicity against HT-29 and MCF-7 cancer cell lines in MTT assays. Enzyme inhibition studies demonstrated activity against glucose-6-phosphate dehydrogenase (G6PDH) and lactate dehydrogenase (LDH), indicating potential relevance to cancer metabolism. Moderate acetylcholinesterase inhibition was observed, with IC50 values from 56.81 to 182.40 µM. Antimicrobial testing showed that D1, D3, D4, and D5 were active against selected microbial strains, while D2 and D6 were inactive. Density functional theory (DFT) calculations, molecular docking, ADME/T predictions, and molecular mechanics simulations were conducted to complement the experimental findings. These computational analyses indicated favorable binding interactions and pharmacological profiles.In summary, the newly synthesized triazole-based Mannich derivatives represent promising candidates for further pharmacological investigation.
AtıfOpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ2Effects of transcutaneous auricular vagus nerve stimulation added to robotic rehabilitation in patients with ischemic stroke: a randomized clinical trial
Kızıl, Ömer Dicle; Ural, İbrahim Halil; Hatık, Sefa Haktan; Özden, Ali Veysel; Aydın, Emine Büşra
Background: This study aimed to investigate the effects of adding transcutaneous auricular vagus nerve stimulation (taVNS) to robotic rehabilitation on functional outcomes and neuromuscular activity in patients with ischemic stroke. Methods: This randomized controlled clinical trial employed a pre–post study design and was conducted in a hospital-based physiotherapy and rehabilitation clinic. A total of 40 patients with ischemic stroke, aged 18–65 years, were randomly assigned to either a robotic rehabilitation group (RRG) or a combined vagus nerve stimulation and robotic rehabilitation group (VRRG). Spasticity, walking speed, motor function, quality of life, muscle activity, and pain were assessed at baseline and after six weeks of treatment. Results: Primary outcome measures were walking speed, motor function assessed by the Fugl–Meyer Assessment, and pain intensity. Secondary outcomes included electrophysiological measurements (H-reflex and F-wave parameters) and quality of life. Within-group analyses showed significant improvements in all outcomes in the VRRG (p < 0.05), whereas all outcomes except pain improved significantly in the RRG (p < 0.05). Between-group comparisons demonstrated greater improvements in walking speed in the VRRG compared with the RRG (mean difference − 1.84 s, 95% CI − 3.7 to − 0.7; r = 0.43; p = 0.006) and greater pain reduction in the VRRG (mean difference − 1.55, 95% CI − 2.5 to − 0.1; r = 0.30; p = 0.048). In contrast, a greater reduction in the Hmax/Mmax amplitude ratio—an electrophysiological marker of spinal excitability—was observed in the RRG. Conclusion: The findings suggest that transcutaneous auricular vagus nerve stimulation combined with robotic rehabilitation may provide additional benefits in terms of walking speed and pain reduction in patients with ischemic stroke. Trial registration: The study was registered at ClinicalTrials.gov on April 19, 2024. (Identifier: NCT06381089).
- MakaleAçık Erişim2026Scopus SJRQ1Thermochemical Activation of Lightweight Slag–Perlite Alkali-Activated Slag (AAS): Overcoming Aggregate Brittleness and Sulfate Degradation
Eker, Hasan; Demir Şahin, Demet
The successful realization of a circular economy in the cement industry, coupled with a substantial reduction in carbon emissions, relies on the development of sustainable alternative binder systems. This study investigated the physicomechanical performance and sulfate resistance of composites produced by alkali activation of natural perlite and blast furnace slag. The aim of the research was to improve mechanical properties under low- and medium-alkalinity conditions (5–10 M NaOH). The samples were cured at an ambient temperature of 20 °C and then treated with heat at 60 °C. These samples were then mechanically processed and subjected to five soak–dry cycles in 5% and 10% Na2SO4 solutions. The results showed that heat treatment resulted in the formation of a dense C-A-S-H gel, increasing compressive strength approximately eightfold, from 11.64 MPa to 92 MPa. However, perlite’s porous and brittle structure limits its flexural strength to 0.27 MPa; this value is insufficient for structural applications. Under severe sulfate attack (10% Na2SO4), samples cured at ambient temperature showed a 12% mass increase in the first cycle due to solution infiltration into capillary voids. As a consequence of extensive ettringite and gypsum formation, the specimens experienced severe deterioration, resulting in a complete loss of mechanical integrity and a residual compressive strength of 0 MPa. In contrast, heat-treated samples showed limited ion diffusion due to a denser matrix and an improved aggregate interface transition zone, resulting in a 2.6% mass increase and a residual compressive strength of 5.17 MPa. Consequently, the obtained findings indicate that thermally treated alkali-activated slag–perlite composites exhibit high resistance against sodium sulfate attack and may have potential for use in specific industrial environments with high sulfate concentrations. However, the performance of these materials under more complex aggressive conditions, such as mining environments involving magnesium sulfate exposure and acidic drainage waters, should be further validated through future studies.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2026Scopus SJRQ4Impact of cooking methods on PAH formation in traditional Akçaabat meatballs
Bostan, Sinan; Gül, Abdulkadir; Karpuz, Ömer; Baltaci, Cemalettin; Yılmaz, Fırat
Akçaabat meatballs, a traditional and commercially important Turkish meat product, are widely consumed and typically prepared using high-temperature cooking methods that may promote the formation of polycyclic aromatic hydrocarbons (PAHs). This study aimed to evaluate the effect of different cooking techniques, including pan cooking without added oil (dry pan cooking), electric grilling, oven baking, charcoal barbecue, and hazelnut shell charcoal barbecue, on PAH formation in Akçaabat meatballs. Samples obtained from eight different producers were analyzed for selected chemical properties and PAH contents using HPLC-FLD. While basic compositional characteristics varied among samples, the most significant differences were observed in PAH levels depending on the cooking method. The sum of four priority PAHs (∑PAH4) ranged between 7.70 and 112.38 µg/kg across all treatment s. Among the cooking methods, barbecue applications (charcoal and hazelnut shell charcoal) resulted in the highest PAH levels, frequently exceeding regulatory limits. In contrast, electric grilling produced the lowest PAH concentrations and showed the highest compliance with food safety standards. These findings demonstrate that cooking method plays a critical role in PAH formation and highlight the importance of selecting appropriate cooking techniques to minimize health risks. In this context, electric grilling can be considered a safer alternative, whereas traditional charcoal-based cooking methods may pose a significant risk in terms of PAH exposure.
- MakaleAçık Erişim2026Scopus SJRQ1Isolation and Preliminary In Vitro Characterization of a Honey-Derived Bacillus licheniformis Isolate
Usta, Mehtap; Zengin, Kübra; Kara, Yakup; Nalçacıoğlu, Remziye; Demirbağ, Zihni; Yıldız, Oktay; Kolaylı, Sevgi
Background/Objectives: Despite its hostile physicochemical environment characterized by high osmotic pressure, acidic pH, and low water activity, honey serves as a unique ecological niche for resilient microorganisms. This study aimed to recover bacterial isolates from honeys of different botanical origins and to characterize the probiotic-associated properties of a honey-derived Bacillus licheniformis isolate. Methods: A total of 20 bacterial isolates were recovered from four honey samples, including two blossoms and two honeydew honeys. 16S rRNA gene sequence analysis showed that the recovered isolates had taxonomic assignments consistent with Bacillus licheniformis. Because 16S rRNA sequencing does not provide sufficient resolution to establish strain-level diversity or clonality, one isolate, designated Blhoney, was selected for subsequent molecular and functional characterization. Results: In vitro assays revealed that Blhoney exhibits robust tolerance to simulated gastrointestinal stress, including extreme acidity (pH 1–3), bile salts (0.3–1%), pepsin, and pancreatin, maintaining viability for up to 24 h. Phenotypic antimicrobial testing demonstrated measurable inhibition zones for erythromycin, kanamycin, chloramphenicol, ampicillin, tetracycline, gentamicin, streptomycin, and spectinomycin, whereas no measurable inhibition zones were observed for penicillin G, rifampicin, ciprofloxacin, or ceftazidime. However, MIC determination and standardized breakpoint interpretation were not performed; therefore, these findings were interpreted solely as preliminary phenotypic inhibition-zone observations. Although the isolate did not display direct antagonistic activity against the tested bacterial pathogens under experimental conditions, its persistence under the tested gastrointestinal stress conditions supports further investigation of its probiotic-associated characteristics. Conclusions: Overall, these findings indicate that the honey-derived Blhoney isolate exhibits preliminary probiotic-associated characteristics under the tested in vitro conditions. However, further strain-level genomic and safety characterization is required before its potential probiotic application can be established.
- MakaleYalnız künye2026Scopus SJRQ2Natural (226Ra, 232Th, 40K) and artificial (137Cs) radioactivity assessment of Kırkpavli and Hazine Cave ore deposits, Gümüşhane (Türkiye): Radiological risk and material utilization perspective
Vural, Alaaddin; Kaya, Ali
Environmental radioactivity is a critical factor for both ecological and human health risk assessment, particularly in mining regions with ongoing or historical settlement activities. This study evaluates natural and artificial radionuclide concentrations in soils from the Kırkpavli (KP) and Hazine Cave (HM) mining areas in Gümüşhane, northeastern Türkiye. Gamma spectrometry analyses were performed to measure 232Th, 226Ra, 40K, and 137Cs, and radiological risk indicators—including absorbed dose rates, annual effective dose, radium equivalent activity, hazard indices (Hex and Hin), Excess Lifetime Cancer Risk (ECLR), Activity Utilization Index (AUI), radon-related alpha index, and natural radioactivity-driven heat production (RHP)—were assessed. Results: showed spatial variability linked to lithology, with the HM site exhibiting elevated radionuclide levels in basalt-dominated units, while KP soils showed moderate values in sedimentary formations. Most radiological parameters remained below international safety limits; however, specific sampling points, particularly HM-2, exceeded thresholds, indicating potential health risks if the soils are used for local settlement, building materials, or domestic purposes. RHP analysis further identified areas of intense hydrothermal alteration correlating with higher natural radioactivity. Comparisons with international soils and rocks confirmed that the activity concentrations at both sites are comparable to or exceed global averages. These findings highlight the necessity of ongoing monitoring of naturally occurring radioactive materials (NORM) in inhabited mining regions and provide essential data for ensuring environmental safety, sustainable land and material use, and public health protection.
- MakaleYalnız künye2026Scopus SJRQ1Impact of soil-structure interaction on earthquake response of high-rise steel frames equipped with TMD and FTMD optimized through cloud drift optimization
Alibabaei Shahraki, Mohammad; Araz, Onur; Ahmadi, Hossein
Vibration control of tall buildings under various seismic and foundation conditions remains a critical issue in earthquake engineering. This paper investigates the performance of Tuned Mass Damper (TMD) and Friction Tuned Mass Damper (FTMD) systems in reducing the seismic response of fixed-base and Soil-Structure Interaction (SSI) analyses of 20- and 40-storey steel moment-resisting frames. The current study uses the OpenSees software and the Cloud Drift Optimization (CDO) technique, aiming at minimizing the normalized H 2 -norm of the roof displacement. The performance of the seismic control is investigated by performing nonlinear dynamics analyses with the help of a set of 14 records, of which 7 records are far-field and the remaining ones are near-field records. Results show that both TMD and FTMD are effective in decreasing roof displacement on 20- and 40-story buildings subjected to fixed-base and SSI excitations. More precisely, results for the average reduction in roof displacement are 33.4% and 27% when FTMD is subjected to SSI loading, while those values were 10.7% and 16.5% when TMD was subjected to SSI loading in the case of 20- and 40-story buildings, respectively. Results are based on multiple variables including base shear, kinetic energy, and damping energy. The results demonstrate that the FTMD system provides superior seismic response reduction compared to the conventional TMD.
AtıfScopus5WoS5OpenAlex2İncele - MakaleYalnız künye2026Scopus SJRQ1Effects of an Immersive Virtual Reality-Based Exercise-Rest on Mobilization in Knee Surgery Patients: A Single-Blind, Randomized Controlled Trial
Aydin, Aydanur; Menekşeoğlu, Ahmet Kıvanç; Dilaver, İrem; Taş, Süleyman Kasım
Purpose This study aimed to evaluate the impact of immersive virtual reality (IVR) interventions on enhancing mobilization in patients undergoing total knee arthroplasty. Design A randomized, single-blinded, two-arm, parallel-group controlled trial. Methods A randomized controlled trial was conducted on 30 patients who underwent total knee arthroplasty for the first time. Participants were divided into two groups: the intervention and control groups. The primary outcome, mobilization distance, was measured at the first postoperative mobilization using validated scales. Before mobilization, patients in the intervention group experienced a simulated walk through a tranquil forest accompanied by birdsong and meditation music via IVR goggles. Results All surgeries were performed by the same surgeon, and postoperative medical care was standardized across both groups. The intervention group demonstrated significantly greater mobilization distances and shorter initial walking times than the control group. Moreover, patients in the intervention group reported reduced postmobilization pain and expressed high satisfaction with the IVR experience. Conclusions The findings indicate that patients who experienced IVR intervention exhibited reduced postmobilization pain, increased mobilization distance, and higher satisfaction. This innovative technique has the potential to serve as a practical solution to enhance clinical improvement in various healthcare settings. Clinical Implications This study demonstrated the effectiveness of IVR-assisted mobilization in enhancing walking distance among patients undergoing knee surgery. The use of IVR presents an innovative and engaging approach to support postoperative mobilization in this patient population. Further research in this area may contribute to the development of more comprehensive and effective IVR interventions.
- MakaleAçık Erişim2026Scopus SJRQ1Serum and hepatic lipid fractions and total protein status of laying hens supplemented with tarragon (Artemisia dracunculus L.) under different stocking densities
Kaya, Hacer; Karaalp, Musa; Kaynar, Özgür; Elmastaş, Mahfuz
High stocking density can induce metabolic disturbances in laying hens, particularly in lipid metabolism. This study evaluated the effects of dietary tarragon (Artemisia dracunculus L.) supplementation on serum and hepatic total protein and lipid parameters in laying hens reared under different stocking densities. A total of 192 50-week-old Lohmann Brown laying hens were assigned to a 2 × 4 factorial arrangement with two stocking densities, 5 or 7 hens per cage, and four dietary tarragon treatments providing 0, 1, 5, or 10 mmol/kg feed of tarragon-derived additional antioxidant activity for 8 weeks. Serum total protein concentration was not affected by stocking density but increased with tarragon supplementation, rising from 7.5 to 8.3 g/dL. Liver total protein concentration remained unchanged. SDS-PAGE analysis of pooled treatment-group samples identified 24 serum and 39 hepatic protein bands. High stocking density altered the serum lipid profile by increasing cholesteryl ester, free fatty acid, and acylglycerol proportions, as well as total cholesterol and triacylglycerol concentrations, while decreasing triacylglycerol and phospholipid proportions. Tarragon supplementation increased serum cholesteryl ester and phospholipid proportions and reduced serum triacylglycerol and free fatty acid proportions, together with lower total cholesterol and triacylglycerol concentrations. In the liver, high stocking density increased cholesteryl ester and free cholesterol proportions and triacylglycerol concentration, whereas it decreased triacylglycerol and phospholipid proportions and total cholesterol concentration. Tarragon supplementation increased hepatic cholesteryl ester, free cholesterol, and phospholipid proportions and reduced hepatic triacylglycerol proportion and concentration. Significant stocking density × tarragon-derived additional antioxidant activity interactions were observed for serum free fatty acid and hepatic free fatty acid and free cholesterol. Overall, stocking density had a stronger effect on lipid metabolism than on total protein status.
