Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2023
    The Mediating Role of Perceived Value in the Influence of Online Consumer Reviews on Destination Brand Loyalty

    Ödemiş, Murat

    Information technologies are rapidly showing their effect in the tourism industry as well as in every field. Online platforms have become a significant channel where consumers frequently share their consumption experiences and take them into account in their destination preferences. If managed effectively by destinations, it can become an effective tool in shaping consumer perception and brand loyalty. According to this, it is aimed to detect whether perceived value (PV) has a mediating role in the influence of online consumer reviews (OCRs) on destination brand loyalty (DBL) in the research. The sample of the research comprises of 315 attendants who visit Istanbul for touristic purposes. Research data were collected with the survey data gathering tool. After testing the data obtained from the attendants in terms of normality, reliability and construct validity, the relationships between the variables were investigated by correlation analysis. In the last stage, the hypotheses of the research were tested with simple linear regression and hierarchical regression analysis. Consequently, the basis hypothesis (H4) of the research, "the mediating role of PV in the influence of OCRs on DBL" were accepted with full mediation influence, and also accepted other hypotheses of research (H1, H2 and H3).

    AtıfOpenAlex1
    TR Dizinİncele
  • MakaleAçık Erişim2023
    3B Şekil Oluşturmak için Alt Örneklemesiz Shearlet Dönüşümüne Dayalı Yeni ve Yüksek Kaliteli Odaklama Ölçüm Operatörü

    Doğan, Ramazan Özgür; Dogan, Hulya

    3B şekil oluşturulma sürecinde herhangi ek donanım gerektirmeyen Odaktan Şekil (Shape From Focus - SFF) en çok tercih edilen stratejilerdendir. SFF stratejisi, 3B şekil oluşturma sürecinde farklı odaklı 2B görüntü serisi kullanmakta ve üç temel aşamadan oluşmaktadır: (1) Farklı odaklı 2B görüntü serisinin elde edilmesi, (2) Görüntü piksellerinin odaklama değerlerinin hesaplanması ve (3) Maksimum odaklı pikselin seçilmesi. Yüksek doğruluk ve daha düşük gürültü ile 3B şekil oluşturmak için, araştırmacılar SFF'nin ikinci aşamasında yeni odaklama ölçüm operatörü önermek yerine genellikle bir ön veya son işlem algoritmaları geliştirmektedirler. Literatür çalışmalarının aksine, bu çalışmada herhangi bir ön veya son işlem gerektirmeyen Alt Örneklemesiz Shearlet Dönüşümü'ne dayalı yeni ve yüksek kaliteli odaklama ölçüm operatörü önerilmektedir. Önerilen odaklama ölçüm operatörünün etkinliği sentetik görüntü serileri kullanılarak pencere boyutu ve gürültü seviyesi gibi farklı koşullar altında analiz edilmektedir. Elde edilen öznel ve nesnel sonuçlar önerilen odaklama ölçüm operatörünün daha iyi performans sağladığını göstermektedir.

    AtıfOpenAlex3
    TR Dizinİncele
  • MakaleAçık Erişim2023
    Patient Safety Culture Perception Among Surgical Nurses

    Aydin, Aydanur; Gürsoy, Ayla; Candas Altinbas, Bahar; Cilingir, Dilek; Bulut, Enes; Ertürk Yavuz, Melek

    Background: Human and technology factors in healthcare can lead to errors that threaten human life. A strong patient safety culture in hospitals may be linked to better patient outcomes. Because of the potential for mistakes in surgical departments, surgical nurses are critical to establishing and maintaining a patient safety culture. Aim: The aim of this study was to explore the patient safety culture perceptions of surgical nurses. Methods: This descriptive study was performed with 206 nurses working in the surgical clinics and operating rooms of 1 university hospital, 2 public hospitals, and 1 private hospital. A “Questionnaire” and the “Hospital Survey on Patient Safety Culture” were used for data collection. The data were analyzed using mean, number, and percentage values, 1-way analysis of variance, Tukey Honestly Significant Difference (HSD), and chi-square tests. Results: The study revealed that surgical nurses’ patient safety culture perception was at a medium level. The highest mean rate of positive responses in The Hospital Survey on Patient Safety Culture came from “Teamwork within units” and the lowest mean rate of positive answers came from the “Non-punitive response to errors” subdimension. In addition, 85.7% of the surgical nurses did not report any errors in the previous 1 year, and nurses who had been working for ≥11 years submitted more error reports (P = .001). Conclusion: Nurses’ patient safety culture perception was at a medium level. Recommendations for improving patient safety culture should include on-the-job training programs and improvements in employees’ working conditions.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfOpenAlex3
    TR Dizinİncele
  • MakaleAçık Erişim2023
    Effect of different specific warm-up protocols and time of day on optimum power performance in kickboxers

    Bayrakdaroğlu, Serdar; Koç, Hürmüz; Yağın, Fatma Hilal; Bayer, Ramazan; Nobari, Hadi; Pardos, Elena Mainer; Eken, Özgür

    Numerous variables can affect performance before the competition. Nevertheless, it could be a subject of curiosity to find out whether a warm-up strategy has a more positive effect on the power performance of kickboxers. The purpose of this study is to evaluate the effect of different specific warm-up protocols and time of day on optimum power performance in kickboxers. Ten volunteer males performed three different warm-up routines in random order. The warm-up protocols consisted of only 20 min for each group. The groups with low-intensity aerobic running (NSWU) and specific warm-ups (SWU-20m) performed 20-min protocols. The other group followed 10 minutes of jogging and 10 minutes of specific warm-up (SWU-10m). All groups followed the warm-up randomly at two different periods of the day (i.e. morning: 09:00-10:00 and evening: 16:00-17:00) on non-consecutive days. A statistically significant difference was found between the groups in terms of Mean Propulsion (W) (F=3.518; p2=0.036). There was a statistically significant difference in Mean propulsive Power (W) between NSWU and SWU-10m (p3= 0.0007) in addition there was also a statistically significant difference in SWU-10m and SWU-20m (p3= 0.0106) and, NSWU and SWU-20m (p3= 0.415) protocols. In conclusion, mean propulsion (W) performance showed diurnal variation, and performances of the kickboxers’ can be affected more positively in the evening hours, especially after SWU protocols.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfOpenAlex14TR Dizin1
    TR Dizinİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Chemical Composition of Pistacia terebinthus L. and its Phytochemical and Biological Properties

    Fidan, Muhammed Said; Baltaci, Cemalettin; Öz, Mehmet; Akar, Zeynep

    Vitamin C, enzyme activities, phenolic compounds, antioxidant capacity, antimicrobial activity, and essential oil analyses of ripe and unripe fruits of P. terebinthus were investigated. Vitamin C amounts of ripe and unripe fruits were 63.2 and 15.4 mg/100g, respectively. The main phenolic compounds of unripe and ripe fruits are rutin, syringic acid, and gallic acid. It was determined that the enzyme inhibitor activities in the ripe and unripe fruits were 0.136 mg/mL and 2.14 mg/mL. In all of the free radical scavenging (DPPH and ABTS) activity, ferric (III) ion reducing antioxidant power (FRAP) capacity, total phenolic substance amounts (TPC), total flavonoid substance amounts (TFC), and total antioxidant activity (TAC) antioxidant methods analyzed with plant parts, the methanol extracts obtained from the ripe fruits of the P. terebinthus showed higher antioxidant properties than the methanol extracts obtained from the unripe fruits. Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 showed antimicrobial activity against microorganisms, while methanol extracts obtained from unripe fruit samples did not show antimicrobial activity against the microorganisms used. The chemical grade with the most compounds in the essential oils of P. terebinthus were monoterpenoids, sesquiterpenes, and monoterpenes in unripe and ripe fruits, respectively. The main components were a-pinene with 22.8% and 27.3% ratios in unripe and ripe fruits, respectively.

    • SDG 2 · Açlığa Son
    AtıfWoS9OpenAlex11
    Web of Scienceİncele
  • MakaleAçık Erişim2023
    LEARNING STYLES OF TALENTED PRE- SERVICE TEACHERS

    Türker, Ustun; Bostanci, Ozgur

    The learning styles of students vary both among individuals and across different disciplines they choose to study. In higher education, academic discipline appears to be a key factor influencing students'distinctive learning styles. This study, which aims to determine the dominant learning styles and models of talented pre-service teachers, was designed with the survey model. The study group research consisted of 1019 volunteer pre-service teachers who continued their education in Physical Education and Sports, Music, and Arts & Craft Teaching departments. In the study, the VARK Learning Style Inventory was used as a data collection tool; students were asked to answer questions in a digital environment through Google Forms. According to the research results, kinesthetic style is the dominant learning preference for pre -service teachers in the visual arts and sports sciences, and both kinesthetic and aural styles are the dominant learning preferences for pre-service teachers in music education. Although talented pre-service teachers tend to learn predominantly kinesthetic and aural styles when evaluated, 61.2% of pre-service teachers prefer to learn with a Multiple Learning Model, which covers the entire instructional diversity, rather than sticking to just one learning style.

    • SDG 4 · Nitelikli Eğitim
    AtıfWoS1OpenAlex20
    Web of Scienceİncele
  • MakaleYayıncıda açık erişim2023Scopus SJRQ3
    Antimicrobial, Antioxidant, and Phytochemical Activities of Rhus coriaria L. and its Phenolic Compounds and Volatile Component Analyses

    Öz, Mehmet; Baltaci, Cemalettin; Fidan, Muhammed Said; Karatas, Seyda Merve

    Volatile oil analysis, phenolic constituents, antioxidant capacity, antimicrobial activity, vitamin C, and enzyme activities of the fruits of Rhus coriaria L. were studied. The chemical with the highest percentage was sesquiterpene hydrocarbons with 40.4%. The major compound was detected as caryophyllene (36.9%). The main phenolic constituents of fruit samples were gallic acid, syringic acid, protocatechuic acid, and 4hydroxybenzoic acid. The highest phenolic constituent of fruits was gallic acid. Ferric (Ill) ion reducing antioxidant power (FRAP) capacity (14.9 mg FeSO4 eq./g), free radical scavenging (ABTS) capacity (68.8 mg AA eq./g), ABTS % inhibition rate (98.0%), free radical scavenging (DPPH) (53.1 mg AA eq./g), and DPPH % inhibition (79.6%) amounts were determined in antioxidant capacities of the samples. The bioactive component contents of the samples were total antioxidant amounts (TAC) (32.8 mg GA/g), total flavonoid substance amounts (TFC) (73.8 mg QE eq./g), and total phenolic substance amounts (TPC) (41.4 mg GA eq./g). The results of the antimicrobial activity analysis of R. coriaria fruit samples showed antimicrobial activity against Staphylococcus aureus and Listeria monocytogenes microorganisms. The amount of vitamin C and enzyme inhibitor activity in the fruits of R. coriaria were determined as 35.5 mg/100 g and 0.07 mg/mL, respectively.

    • SDG 2 · Açlığa Son
    AtıfWoS10OpenAlex5
    Web of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ4
    Wear Behavior of Dental Restorative Materials

    Sen, Sadri; Zamanlou, Hamid; Karabudak, Filiz; Süküroglu, Ebru Emine

    Gradual wear of opposing teeth is a normal phenomenon in human dentition. There is a need for quality dental restorative materials to repair or replace natural teeth to ensure a higher quality of life through dental health. One of the main physiological mechanism that exists in dental materials during normal muscle function is called abrasion. There are two types of that in teeth which are common; Two-body and three-body. If the teeth are contacted directly, it is referred to as two-body abrasion. However, when there is abrasive slurry-like food between the teeth, this abrasive is called to be three-body abrasive. Several types of materials are available in current dentistry for teeth restoration and replacement, and new materials are being promoted every year. Dental specialists need to understand the wear mechanisms of these new types of dental restorative materials, alone or in combination with either enamel or other dental restorative material. The present study evaluates the abrasive resistance of three restorative materials groups: direct composites, indirect composites, and ceramics. To define the resistance of the wear, the authors then perform a micro-wear test on chosen materials. The results show that the wear mechanism is abrasive due to its low hardness compared to zirconia ball. The wear path in the nanohybrid (Grandio (R), 87s% w/w (71s% volume) inorganic nanohybrid filler, BisGMA, UDMA, TEGDMA) sample was smooth and without particles. In this study wear FEM analysis calculated for all models and the answers compared with experimental data.

  • MakaleYalnız künye2023Scopus SJRQ4
    ON SOLUTION OF BG-INTEGRAL EQUATIONS

    Güngör, N.

    In this study, we center upon obtaining the solution of linear bigeometric Volterra integral equations of the second kind in the sense of bigeometric calculus. The method of successive substitutions and resolvent kernel method are applied for solving the linear bigeometric Volterra integral equations of the second kind by using the concept of bigeometric integral. The necessary conditions for the bigeometric continuity and the uniqueness of the solution of linear bigeometric Volterra integral equations of the second kind are given in these methods. Finally, some numerical examples are presented to explain the procedure of the method of successive substitutions and resolvent kernel method.

  • MakaleYalnız künye2023
    ON THE SPHERICAL INDICATRIX CURVES OF THE SPACELIKE SALKOWSKI CURVE WITH TIMELIKE PRINCIPAL NORMAL IN LORENTZIAN 3-SPACE

    Aksan, Birkan; Mazlum, Sumeyye Gur

    In this paper, we calculate Frenet frames, Frenet derivative formulas, curvatures, arc lengths, geodesic curvatures according to the Lorentzian 3-space R31, Lorentzian sphere S21 and hyperbolic sphere H2 0 of the spherical indicatrix curves of the spacelike Salkowski curve with the timelike principal normal in R3 1 and draw the graphs of these indicatrix curves on the spheres.

  • MakaleYalnız künye2023
    The Relationship between Urbanization, Energy Consumption and Carbon Dioxide Emissions: Panel Ardl Analysis for Newly Industrialized Countries

    Akyol, Mehmet

    An increase in the world population, technological advancement, and economic concerns bring along an increase in urbanization and energy consumption. Increasing urbanization speed and energy consumption cause environmental problems. The main hypothesis of this study is based on the idea that urbanization rate and energy consumption increase carbon dioxide emissions in developing countries. To test this hypethesis, the study ana-lyzed the relationship between urbanization, energy consump-tion, and carbon dioxide emission specific to newly industrialized countries. Panel ARDL method was utilized in this study that scrutinized the years between 1990 and 2018. According to the long-term results of the analysis, urbanization negatively affects carbon dioxide emission in the country group aforementioned; energy consumption and economic growth that is control vari-able have a positive effect on carbon-dioxide emission. Regarding short-term results, only the energy consumption positively af-fects carbon dioxide emission while other variables are statisti-cally insignificant. The results of the analysis reveal the necessity of policies towards smart city applications in reducing carbon dioxide emissions in newly industrialized countries. In addition, turning to renewable sources in energy consumption plays a key role in reducing carbon dioxide emissions.

    • SDG 13 · İklim Eylemi
    AtıfOpenAlex2TR Dizin1
    Web of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023
    Materialistic Tendency and Conspicuous Consumption Behavior: The Mediating Role of Social Media Usage

    Avci, Ibrahim

    This research focuses on the materialistic tendencies and conspicuous consumption behaviors of consumers, especially in today's social media age. The research's goal is to determine the effect of materialistic tendencies on conspicuous consumption behavior and to investigate the role of social media usage in mediating this effect. The data were collected in this context using a prepared survey form, and 596 consumers participated in the survey during the data collection process. SPSS and AMOS programs were used to analyze the collected data. As a result of the analyses, it was discovered that the materialistic tendency had a positive and significant effect on both conspicuous consumption behavior and social media usage; it was also discovered that social media usage had a positive and significant effect on conspicuous consumption behavior. Furthermore, it was determined that social media usage has a partial mediation in the effect of materialistic tendency on conspicuous consumption behavior; in other words, a portion of the effect of materialistic tendency on conspicuous consumption behavior is realized through social media usage. Suggestions for both theory and practice were made in light of these findings.

    AtıfWoS2OpenAlex3
    Web of Scienceİncele
  • MakaleAçık Erişim2023
    Foreign Aid, Institutions, and Economic Performance in Developing Countries

    Hayaloglu, Pinar

    Although official development assistance presents a solution for developing countries to overcome the lack of capital, there is no consensus in the literature on the effectiveness of foreign aid. Moreover, opinions claiming that aid can only affect growth positively under certain conditions see institutional quality as an essential aspect that boosts the positive impact of aid. This study examines the relationships between foreign aid, institutional structure, and economic performance for 80 countries in Europe, America, Africa, and Asia. It is found that official development assistance and the quality of institutional structure in the sample countries affect economic growth positively. It also provides some suggestive evidence showing that foreign aid has a positive effect on the institutional structure.

    • SDG 8 · İnsana Yakışır İş ve Ekonomik Büyüme
    • SDG 17 · Amaçlar için Ortaklıklar
    AtıfWoS3OpenAlex4TR Dizin1
    Web of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023
    Relationship between Institutional Quality and Corruption: The Case of Turkey

    Çiçen, Yildirim Beyazit

    The relationship between the level of corruption and the quality of Turkey's institutional structure was investigated in this study. Using quarterly data between 1984-2015, RALS-ADF unit root and RALS-EG cointegration tests were used to determine if there is a relationship between these variables in Turkey. Corruption level is the dependent variable, institutional quality is the independent variable, and the total production index is the control variable. The first analysis included both the coalition and single-party periods. Also, a separate analysis was carried out for the coalition period 1984-2002. There was no correlation between corruption and institutional quality in either analysis.

    • SDG 16 · Barış, Adalet ve Güçlü Kurumlar
  • MakaleAçık Erişim2023
    Determining the most suitable sectors in terms of the digital supply chain by integrated fuzzy MCDM approach

    Gergin, Ramazan Eyuep

    In this day and age, businesses come up against several challenges due to digital progresses in their supply chain. Digitalization has been expected to play an increasingly important role for both companies and the supply chains of the future. Concordantly, it is important to determine the suitability of the supply chains of the sectors for digitalization in order to cope with the difficulties that the enterprises will face in the future. The main objective of this study is to determine the suitability of the supply chains of the sectors in which medium-sized enterprises operate for digitalization. For this purpose, the criteria which affecting the constitution of the digital supply chain are determined with a comprehensive literature search. Fuzzy Analytical Hierarchy Process (FAHP) is utilized to weighting of the relevant criteria. Sectors which medium-sized enterprises are constitute the alternatives of the study. After the weighting of the criteria, in terms of digital supply chain the suitability of the sectors was evaluated via Fuzzy TOPSIS (FTOPSIS) and Fuzzy VIKOR (FVIKOR). BORDA count technique is utilized to obtain the final decision by integrating the results from these two methods. According to the results of the study, the most important criterion in terms of Global Connectivity digital supply chain was determined as the Manufacturing sector according to FTOPSIS and the Health sector has been determined as the most suitable sector for digitalization according to FVIKOR. As to BORDA Count method, results show that the manufacturing sector is the most suitable sector for digitalization in the general ranking.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfWoS1OpenAlex1TR Dizin1
    Web of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023
    How Does Being Trusted Affect Sharing? Findings from the Ultimatum Game

    Çiçen, Yildirim Beyazit

    According to economic models, individuals are rational, possess full knowledge, and strive to maximize their utility beyond their actual characteristics. Nevertheless, in the real world, people shape their behavior within a social structure and can display altruistic attitudes. This study investigates how trust facilitates sharing among individuals. To determine this, the Ultimatum Game was conducted with 412 participants. Three cases were determined, and the bidder was instructed to divide 10 thousand TL first in the typical game. Afterward, it was said that the other person was in need, and the bid was requested to be renewed. At the last stage, bids were received if there was any doubt about the needy. According to the typical game, people are more empathetic towards those in need and offer 6667 TL rather than 4264 TL. However, when a question of reliability is raised, 4658 TL is offered regardless of need. The findings show that the neoclassical economics concept of homo economicus, which seeks to maximize utility, is not valid in real life.

    • SDG 10 · Eşitsizliklerin Azaltılması
    • SDG 16 · Barış, Adalet ve Güçlü Kurumlar
  • MakaleAçık Erişim2023
    The Culture of Living on Screen and the Audience-Human as Screenshot

    Demir, Sertac Timur

    This paper asserts the idea that everyday life is screened while screens are humanised. As a matter of fact, the screens, which once consisted of detached mechanisms limited to certain places and positioned in front of the audience, at this point, surround the spaces and people. Televisions, mobile phones, tablets, laptops, desktop computers, automobile screens, smart technologies, and flashing billboards are reshaping the connections of modern individuals with the space they live in, the time they feel, the relationships they develop, and their own beings. So much so that the screens that are connected to almost all devices and organize daily life entirely cease to be a platform for viewing images and turn into a kind of spectator's eye. In this regulation, the modern human performs many vital acts from working to having fun, from learning to experiencing, from adapting to resisting not through the screen as it once was, but now as the screen. This screen culture, which basically imitates and perhaps targets the eye, has become one of the norms of digital life. The theoretical framework of this research, which tries to see both the premises of the rapid transformation in question and to trace the ambiguous course, consists of the works of pioneering thinkers such as Gunther Anders, Jean Baudrillard and Byung-Chul Han. For this purpose, in this qualitative study, sociological film analysis is carried out through the episode of Fifteen Million Merits (2011) of the series Black Mirror, one of the Sci-Fi examples that have become very popular in recent years. This episode is notable in terms both of embodying and of nurturing discussions about the screen society.

  • MakaleAçık Erişim2023
    Analysis of Basin Characteristics for Stream Management Using GIS: A Case Study of Gümühane Micro-Watershed

    Çakir, Gunay

    Aim of study: Topography and climatic conditions have effected in determining the processes of the streams of the micro-watershed. Nowadays, the management plans were made for water and soil protection measures in the basins. Area of study: This study was carried outto characterize and prioritize the streams of the Gumushane upper Harsit micro-watershed using a GIS-based spatial approach. Material and methods: Fundamental watershed characteristics including drainage density, slope, land use types, and stream class were evaluated and interpreted for the Gumushane micro-watershed. Calculatea comprehensive value for each parameter, drainage density (Dd), flow frequency (Fs), slope (S), length of land flow (Lg), and land use (Lu) was used. Main results: The drainage density, stream flow frequency, and form factor of the microwatershed are from-4 to 26. Finally, the weighted rankings were summarized, and all micro-watersheds were categorized to five classes based on the risk index as very low risk, low risk, medium risk, high risk, and very high risk. This risk map overlaid to land use type maps in GIS where risk areas were evaluated in the finalrisk results. The 739 ha productive forest area within very high-risk areas was changed to non-risk parameters. Highlights: The carrying capacity of streams was calculated using the stream density of streams in the Gumushane micro-watershed. The risk values produced by streams that pass through neighborhoods where land use values for preventing erosion are present.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
    • SDG 15 · Karasal Yaşam
    AtıfWoS1OpenAlex2TR Dizin1
    Web of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023
    Technological Convergence in Emerging Economies: An Investigation with Unit Root Tests

    Zuhal, Mustafa

    Technological developments play an important role in economic growth and development and form the basis in the convergence of socioeconomic factors between developed and developing countries, especially income. At the same time, developing countries aim to catch up with the leading countries by improving their technological capabilities, and examining the technological convergence between countries, especially developing countries, is essential at this stage. This study aims to examine whether technological convergence occurs in 10 emerging economies. For this purpose, the study analyzes technological convergence over the variables of number of patents, labor productivity, and total factor productivity using Pesaran's (2007) cross-sectionally augmented Dickey-Fuller (CADF) and seemingly unrelated regression augmented Dickey-Fuller (SURADF) unit root tests. According to the results of the analysis, although there is convergence in some countries, it does not confirm in general technological convergence among the countries.

    • SDG 8 · İnsana Yakışır İş ve Ekonomik Büyüme
    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfWoS2
    Web of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023
    Neuropsychological and clinical correlations of optical coherence tomography findings in patients with schizophrenia

    Kani, Ayse Sakalli; Çam, Cansun Sahin; Çelik, Esra Biberoglu; Dural, Uzay; Dönmez, Melike Duran; Turhan, Semra Akkaya; Toker, Ayse Ebru; Yildiz, Mesut

    Objective: There are increasing studies examining retinal fiber layer (RNFL) and ganglion cell layer (GCL) thinning in patients with schizophrenia. However, the results are controversial, and clinical and cognitive reflections of these findings remain unclear. With this study, we aim to examine retinal abnormalities and establish correlations with cognitive and clinical parameters.Methods: In this cross-sectional study, we examined 29 patients with schizophrenia and 13 age and gender-matched healthy controls. All participants underwent psychometric assessment, neuropsychological tests, and optical coherence tomography (OCT) measurements. The retinal fiber layer and ganglion cell layer thickness were used as retinal parameters.Results: Five patients dropped out during the OCT measurement process, 24 patients with schizophrenia and nine healthy controls were included in the analysis. There was no statistically significant difference between groups in measuring retinal nerve fiber layer or ganglion cell layer thicknesses. The verbal fluency test score negatively correlated with left RNFL superior (p = - .422, p <.05). STROOP response duration positively correlated with right RNFL on average (p = .551, p <.05), left RNFL on average (p = .498, p <.05), right RNFL superior (p = .507, p <.05), left RNFL superior (p = .461, p <.05) and right RNFL temporal values (p = .434, p <.05). STROOP response error was also positively correlated with right RNFL temporal thickness (p = .430, p <.05). STROOP response duration was positively correlated with right GCL total (p = .646, p <.01), right GCL superior (p = .658, p <.01) and right GCL inferior (p = .596, p <.01) thickness.Conclusion: We did not find a significant relationship between reduced RNFL or GCL thickness and cognitive impairment. However, we had several positive correlations between cognitive task scores and RNFL and GCL thicknesses. Additionally, our study did not correlate symptom severity and clinical severity parameters with reduced RNFL or GCL thickness.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfWoS1OpenAlex2
    Web of Scienceİncele