Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Öz, Mehmet(7)
- Baltacı, Cemalettin(5)
- Fidan, Muhammed Said(5)
- Aygül, İmdat(4)
- Akmeşe, Osman(3)
- Baltaci, Cemalettin(3)
- Sefalı, Abdurrahman(3)
- Akar, Zeynep(2)
- Karatas, Seyda Merve(2)
- Tunç, Merve Tuğçe(2)
- Ucuncu, Osman(2)
- Akşit, Berfin(1)
- Atici, Ökkeş(1)
- Aydin, İhsan(1)
- Baltaci, C.(1)
- Cansu, Tayyibe Beyza(1)
- Celep, İnci Kurt(1)
- Daǧdemir, Elif(1)
- Erdoǧan, Ümmügülsüm(1)
- Gül, Abdulkadir(1)
- Gündoǧdu, Engin(1)
- Ilter, S. M.(1)
- Juhaimi, Fahad Al(1)
- Karakuş, Sinem(1)
- Karaköse, Mustafa(1)
- Karaoglu, Sengül Alpay(1)
- Karataş, Şeyda Merve(1)
- Kaya, A. A.(1)
- Koca, İlkay(1)
- Köse, Cafer(1)
- Odabaş, Halil İbrahim(1)
- Oz, Mehmet(1)
- Said Fidan, M.(1)
- Saruhan, Emrah(1)
- Sinek, Kadriye(1)
- Tanriverdi, Ebru Sandal(1)
- Türkuçar, Semra Alkan(1)
- Ucuncu, O.(1)
- Yayli, Nurettin(1)
- Yücel, Murat(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ3Chemical Profiling of Stachys cretica subsp. anatolica Rech. f. (Endemic) Essential Oils and their Methanol Extracts with Evaluation as Enzyme Inhibitors, Antioxidant, and Antimicrobial Agents
Öz, Mehmet; Fidan, Muhammed Said; Baltacı, Cemalettin; Akmeşe, Osman; Sefalı, Abdurrahman; Aygül, İmdat
Enzyme inhibition activities, phenolic compounds, antioxidant activities, bioactive compounds, antimicrobial activities, and chemical components of essential oil and methanol extracts obtained from the aerial parts of S. cretica subsp. anatolica were investigated. The main phenolic compounds of aerial parts were catechin, oleuropein, and epicatechin. The determined enzyme inhibitor activities highlight the potential of S. cretica subsp. anatolica as a source of bioactive compounds, particularly for carbonic anhydrase and cholinesterase inhibition. The essential oil and methanol extract exhibited remarkable activities against CA-II, AChE, and BChE, although they were less potent than standard inhibitors. The essential oils generally showed stronger antimicrobial activity compared to the 30% methanol extracts across most bacterial and fungal strains, as evidenced by minimum lethal concentration (MLC) and lower minimum inhibitory concentration (MIC) values and larger inhibition zones. Chloramphenicol used alone exhibited the highest antimicrobial efficacy, with the lowest MIC and MLC values and the largest inhibition zones. The essential oils of S. cretica subsp. anatolica were determined as esters, oxygenated sesquiterpenes, and aldehydes in aerial parts. The main components were found to be hexahydrofarnesyl acetone in the aerial parts.
AtıfScopus3İncele - MakaleAçık Erişim2026Scopus SJRQ3Chemical Profiling of Essential Oils and Evaluation of Enzyme Inhibition, Antioxidant, and Antimicrobial Activities in Both Methanol Extract and Essential Oils of Centaurea oltensis
Aygül, İmdat; Akşit, Berfin
The phytochemical composition and biological activities of Centaurea oltensis, an endemic species in Türkiye, were studied. GC–MS/FID analysis identified 128 compounds representing 99.2% of the EO, with decanoic acid (15.1%), α-pinene (7.9%), and sabinyl acetate (5.4%) as the principal constituents. GC–MS/FID analysis identified 128 compounds representing 99.2% of the essential oil (EO), with decanoic acid (15.1%), α-pinene (7.9%), and sabinyl acetate (5.4%) as the principal constituents. LC–MS/MS analysis of the methanol extract (ME) revealed high concentrations of ferulic acid (2410 µg/g dw) and chlorogenic acid (1170 µg/g dw), together with caffeic, salicylic, and 4-hydroxybenzoic acids. The ME exhibited potent carbonic anhydrase-II inhibition (IC₅₀ = 0.028 µg/mL) and significant α-glucosidase inhibition (IC₅₀ = 0.255 mg/mL). The EO showed strong acetylcholinesterase and butyrylcholinesterase inhibitory activities, with IC₅₀ values of 0.0145 µg/mL and 0.204 µg/mL, respectively. Antioxidant assays, including DPPH, ABTS, and FRAP, demonstrated superior activity of the ME, correlating with its higher phenolic and flavonoid contents. The EO displayed remarkable antibacterial activity against Staphylococcus aureus (MIC = 0.02 mg/mL) and moderate antifungal activity against Candida albicans. Overall, C. oltensis demonstrated considerable chemical diversity and promising antioxidant, antimicrobial, neuroprotective, and enzyme inhibitory potential for future pharmacological and therapeutic applications.
- MakaleAçık Erişim2026Scopus SJRQ3Chemical Profiling and Biological Activities of Methanol Extracts and Essential Oils From Ferulago Platycarpa Boiss. & Balansa (Endemic): Enzyme Inhibition, Antioxidant, and Antimicrobial Properties
Aygül, İmdat; Öz, Mehmet; Fidan, Muhammed Said; Baltacı, Cemalettin; Akmeşe, Osman; Sefalı, Abdurrahman
This study aimed to evaluate the phytochemical composition and biological activities of Ferulago platycarpa methanol extract (ME) and essential oil (EO). The EO was obtained via hydrodistillation and analyzed by GC-MS, revealing sesquiterpene hydrocarbons as the dominant class, with caryophyllene (65.8%) and α-pinene (9.65%) as the major constituents. The methanol extract was subjected to LC-MS/MS analysis, which identified eleven phenolic compounds, with chlorogenic acid as the most abundant. The extract showed significantly higher total phenolic (1196.22±11.64 mg GAE/100g) and antioxidant (1870.00±17.69 mg QEE/100g) contents compared to the ME. In vitro enzyme inhibition assays demonstrated that the methanol extract exhibited potent inhibitory activity against carbonic anhydrase II (CA-II, ICSO= 0.023 pg/mL), acetylcholinesterase (AChE, ICSO= 110 pg/mL), and butyrylcholinesterase (BChE, IC50= 390 pg/mL). In contrast, the EO showed higher inhibition against α-amylase (IC50= 5920±10.45 pg/mL) and BChE (IC50= 1.32±0.65 pg/mL), while its α-glucosidase showed no inhibition. Antioxidant assays indicated superior activity for the methanol extract compared to the EO. Furthermore, antimicrobial testing revealed that the EO demonstrated broader and more effective antimicrobial action, exhibiting lower MIC and MBC values against several bacterial and fungal strains. Collectively, these results highlight F. platycarpa as a valuable source of bioactive compounds with promising applications in antidiabetic, neuroprotective, antioxidant, and antimicrobial therapies.
- MakaleAçık Erişim2025Scopus SJRQ3Cosmetological potential of the essential oil from the aerial parts of Rubus sanctus Schreb.: Enzymatic inhibition, antibacterial properties, and chemical composition
Yıldırım, Aybeniz; Celep, İnci Kurt; Gül, Abdulkadir
Recently, skin care products and cosmetic preparations with herbal ingredients have attracted considerable interest from the public. Therefore, the cosmetic industry is investigating natural products like essential oils and extracts. This study aimed to determine the anti-aging effects of the essential oil obtained from the aerial parts of Rubus sanctus Schreb. (RsEO), as well as to reveal its chemical composition and investigate its antibacterial activity. The chemical composition of RsEO was determined by using GC-MS. The anti-aging activity of RsEO was evaluated by in vitro studies of anti-collagenase, anti-elastase, anti-tyrosinase, and anti-hyaluronidase activities. The antibacterial potential of RsEO was investigated by the agar-well diffusion method against Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli. RsEO showed significant inhibition against collagenase, elastase, hyaluronidase, and tyrosinase with IC50 values of 80.46, 77.85, 72.71, and 82.71 μg/mL, respectively, and when compared with the positive controls epigallocatechin gallate (IC50: 38.91 μg/mL for collagenase, IC50: 38.91 μg/mL for elastase), tannic acid (IC50: 26.95 μg/mL for hyaluronidase), and kojic acid (IC50: 28.74 μg/mL for tyrosinase), the activities were found to be close. It was determined that the major components of RsEO were pentadecanal (8.88%), dodecanoic acid (7.86%), nonanal (4.32%), and octadecanal (4.08%). RsEO showed moderate antibacterial activity (inhibition zones between 10 and 15 mm) against the tested bacteria compared to ampicillin. This study demonstrated that RsEO is a natural product that has the potential to serve as a promising anti-aging and antibacterial therapeutic agent due to the synergistic effect of its constituent components.
AtıfScopus3WoS3OpenAlex4İncele - MakaleAçık Erişim2025Scopus SJRQ3Chemical composition of essential oils and comparative analysis of enzyme inhibitory, antioxidant and antimicrobial activities in essential oils of endemic Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N. Kilian
Fidan, Muhammed Said; Baltacı, Cemalettin; Akmeşe, Osman; Sefalı, Abdurrahman; Aygül, İmdat; Öz, Mehmet
In this study, essential oil from the aerial parts of Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N. Kilian was extracted via hydrodistillation using a Clevenger apparatus. GC-MS/FID analysis determined aldehydes (28.31%) as the dominant group, with eucalyptol (8.71%) as the main constituent. Antioxidant activities were exhibited using DPPH, ABTS, and FRAP assays, with the essential oil demonstrating relatively higher antioxidant properties. The essential oil also showed higher levels of bioactive components, including total antioxidant capacity (160.26 mg AA eq./100 mL), total phenolic content (21.57 mg GA eq./100 mL), and total flavonoid content (14.85 mg QE eq./100 mL). While G. sericea essential oil demonstrated some antioxidant activity, it was significantly lower compared to the reference standard ascorbic acid (AA). The antimicrobial results showed relatively higher antimicrobial activity compared to most bacterial and fungal strains, as evidenced by lower MIC and MBC values and larger inhibition zones. Nevertheless, chloramphenicol (CH) and nalidixic acid (NA) continually showed superior antimicrobial efficacy, with the lowest MIC and MBC values and the largest inhibition zones. The essential oil also demonstrated potent enzyme inhibitory activity, especially against CA-II, AChE, and BChE, with the lowest IC50 value observed for CA-II, highlighting its potential as a potent enzyme inhibitor. However, the essential oil exhibited comparatively greater inhibition against AChE, BChE and α-amylase but was less effective overall. These findings suggest that the G. sericea essential oil has important antioxidant potential and enzyme inhibitory activity, while the essential oil shows varying efficacy across different enzymes.
- MakaleAçık Erişim2023Scopus SJRQ3Chemical Composition of Pistacia terebinthus L. and its Phytochemical and Biological Properties
Fidan, Muhammed Said; Baltaci, Cemalettin; Öz, Mehmet; Akar, Zeynep
Vitamin C, enzyme activities, phenolic compounds, antioxidant capacity, antimicrobial activity, and essential oil analyses of ripe and unripe fruits of P. terebinthus were investigated. Vitamin C amounts of ripe and unripe fruits were 63.2 and 15.4 mg/100g, respectively. The main phenolic compounds of unripe and ripe fruits are rutin, syringic acid, and gallic acid. It was determined that the enzyme inhibitor activities in the ripe and unripe fruits were 0.136 mg/mL and 2.14 mg/mL. In all of the free radical scavenging (DPPH and ABTS) activity, ferric (III) ion reducing antioxidant power (FRAP) capacity, total phenolic substance amounts (TPC), total flavonoid substance amounts (TFC), and total antioxidant activity (TAC) antioxidant methods analyzed with plant parts, the methanol extracts obtained from the ripe fruits of the P. terebinthus showed higher antioxidant properties than the methanol extracts obtained from the unripe fruits. Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 showed antimicrobial activity against microorganisms, while methanol extracts obtained from unripe fruit samples did not show antimicrobial activity against the microorganisms used. The chemical grade with the most compounds in the essential oils of P. terebinthus were monoterpenoids, sesquiterpenes, and monoterpenes in unripe and ripe fruits, respectively. The main components were a-pinene with 22.8% and 27.3% ratios in unripe and ripe fruits, respectively.
AtıfWoS9OpenAlex11İncele - MakaleAçık Erişim2023Scopus SJRQ3Chemical composition and biological activities of essential oils from the flowers and leaves of Celtis planchoniana K.I.Chr.
Öz, Mehmet; Ucuncu, Osman; Baltacı, Cemalettin; Said Fidan, M.; Karatas, Seyda Merve
Most plant parts are used in traditional food and medicine. Plants are significant resources of potential phytochemicals. This study investigated the properties of essential oil, antioxidant, and antimicrobial activities of the flowers and leaves of the Celtis planchoniana plant. Based on the GC/MS-FID analysis of essential oils extracted from the flowers and leaves of C. planchoniana, 101 and 91 compounds were identified from their structures, respectively. Chemical classes with the highest percentage of compounds found in essential oils of plants were oil acids, with 31.51% in flowers, and aldehydes, with 32.89% in leaves. Hexadecanoic acid (29.94%) and (E)-2-hexenal (16.11%) compounds were determined as the main components in the plant’s flowers and leaves. Among the flower and leaf samples, the highest antioxidant levels were 132.77-80.10 mg AA eq./100 mL in TAC, 17.63-118.23 mg AA eq./100 mL in ABTS, 71.41-85.15 mg GA eq./100 mL in TPC, and 15.08-15.71 mg AA eq./100 mL in DPPH capacity. According to the TFC, TPC, ABTS, DPPH, and FRAP tests conducted to determine the antioxidant properties of C. planchoniana, the essential oil obtained from its leaves demonstrated more significant antioxidant properties than the essential oil obtained from its flowers. According to the antimicrobial activity analysis, the leaf and flower essential oil samples exhibited no antimicrobial activity against the microorganisms tested.
AtıfScopus7WoS6OpenAlex5İncele - MakaleYayıncıda açık erişim2023Scopus SJRQ3Chemical Content and Antimicrobial Activities of Essential Oils Obtained from Plant Parts of Juniperus excelsa M. Bieb.; [Kemijski sastav i antimikrobno djelovanje eteričnih ulja dobivenih iz dijelova biljke Juniperus excelsa M. Bieb.]
Saruhan, Emrah; Öz, Mehmet
This study was conducted to determine the chemical content, antibacterial, and antifungal properties of essential oil obtained from the parts of the plant called Juniperus excelsa M. Bieb. In this study, essential oils of cone, needle, and twig of J. excelsa plant, which is a naturally grown plant in Gümüşhane province, were obtained by hydrodistillation method in a Clevenger type device. Chemical composition of essential oils was determined thanks to the analysis conducted with GC-MS/FID device. Besides, antimicrobial activity tests of essential oils were decided in contrast to 23 different microorganisms with the disc diffusion method. As a result of the essential oil analysis of J. excelsa, the percentage of essential oil yield in cones, needles, and twigs was found as 5.88 %, 2.00 %, and 0.62 %, respectively. α-pinene was confirmed to be the most abundant main compound found in the essential oils of cones, needles, and twigs. As a result of the essential oil analysis of the cone, needle, and twig of J. excelsa species, it was revealed that monoterpenes were the most abundant chemical class in terms of percentage. In the antimicrobial activity test performed on the essential oils of J. excelsa plant parts, it was found that cones, needles, and twigs have a strong antimicrobial effect against Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Escherichia coli O157:H7, Listeria monocytogenes, Salmonella enteritidis, Salmonella typhimurium, Staphylococcus aureus, Candida albicans, Penicillum expansum, Saccharomyces cerevisiae bacteria, yeast, and molds.
AtıfScopus3WoS2OpenAlex1İncele - MakaleYalnız künye2022COMPOSITION OF ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES AND CHEMICAL COMPONENTS OF ESSENTIAL OIL FROM FLOWERS AND LEAVES OF Pyrus elaeagnifolia Pallas IN TURKEY
Fidan, Muhammed Said; Oz, Mehmet; Ucuncu, Osman; Baltaci, Cemalettin; Karatas, Seyda Merve
Gumushane region in Turkey is rich in plant diversity. The flowers and leaves of Pyrus elaeagnifolia Pall. plants that will form the basis of this research were collected from the places determined. In this study; the essential oils of flowers and leaves of P. elaeagnifolia plants were obtained by hydrodistillation method in a Clevenger type device. The chemical composition of volatile oils diluted with hexane were determined by analyzing with a GC-MS/FID instrument. The quantity of antioxidant activity of the obtained essential oils was determined by total phenolic content, free radical scavenging amounts, total flavonoid content, total antioxidant content, free radical scavenging capacity and ferric reducing antioxidant power capacity according to methods. Antimicrobial activity of essential oils was determined against 23 different microorganisms by disc diffusion method. As a result; essential oil yields in percentage are 0.44% and 0.72% in the flowers and leaves of the P. elaeagnifolia. Chemical classes with the highest percentage of compounds in essential oils of plant parts: Hydrocarbons (79.77%) and aldehydes (33.31%) were detected in the flowers and leaves of the P. elaeagnifolia. In addition, the main components found in essential oils are tricosane (36.98%-15.89%) in the flowers and leaves of the P. elaeagnifolia. The determination of antioxidant activity obtained from samples collected from plant parts was determined total phenolic substance amounts in the range of 48.57-68.32 mg GAE/100 mL, free radical scavenging amounts between 9.52-40.95 mg AA/100 mL, flavonoid substance amounts in the range of 1.34-3.95 mg QE/100 mL, total antioxidant amounts in the range of 66.93-185.10 mg AA/100 mL, free radical scavenging capacity between 23.40-81.02 mg AA/100 mL and FRAP capacity in the range of 4.20-10.50 mg FeSO4/100 mL. According to the results obtained with total phenolic content, free radical scavenging amounts, total flavonoid content, total antioxidant content, free radical scavenging capacity and ferric reducing antioxidant power capacity was determined the highest antioxidant properties in leaves of P. elaeagnifolia. According to the results of the antimicrobial activities analysis obtained from the collected samples of plant parts, it was determined that only the flowers of P. elaeagnifolia show antimicrobial activity against the microorganisms used.
AtıfWoS5İncele - MakaleYalnız künye2022Scopus SJRQ3Chemical Composition and Antimicrobial Properties of Essential Oils Obtained from the Resin of Picea orientalis L.
Öz, Mehmet
This study aims to evaluate the chemical composition and antimicrobial (antibacterial and antifungal) properties of the essential oil subtracted from the oleoresins, which were obtained from the stem of the Picea orientalis naturally grown in Turkey. The essential oil of the resin was obtained through the hydrodistillation method in a Clevenger type device, and it was analyzed with GC-MS/FID. The structure of 74 compounds that were found in the essential oil was elucidated by comparing with literature data and the database in the appliance. Limonene (53.40%), β-pinene (20.74%) and α-pinene (14.51%) were determined to be the major components. The highest class of compounds in resin essential oils was identified as monoterpene hydrocarbons. The antimicrobial activity of the essential oil was investigated with the agar well diffusion method against 25 microorganisms, including 13 gram-negative, 7 gram-positive bacteria and 5 yeast-molds. As the results of the analysis, the highest antibacterial activity was recorded against S. typhimurium from gram-negative bacteria with inhibition zone ranging as (13.70±0.10-9.70±0.10 mm) and S. aureus from gram-positive bacteria with inhibition zone ranging as (9.30±0.10-6.80±0.10 mm). Additionally, the highest antifungal activity was obtained against C. albicans from yeast-molds with inhibition zone ranging as (10.10±0.10-6.10±0.10 mm).
AtıfScopus10WoS6OpenAlex6İncele - MakaleAçık Erişim2021Scopus SJRQ1Chemical compositions by using LC-MS/MS and GC-MS and antioxidant activities of methanolic extracts from leaf and flower parts of Scabiosa columbaria subsp. columbaria var. columbaria L.
Akar, Zeynep
The members of the Scabiosa genus are one of the traditional medicinal plants used in the treatment of many diseases, in particular the treatment of scabies. In this study, it was aimed to determine antioxidant activities and chemical composition of methanolic extracts of leaves and flowers of Scabiosa columbaria subsp. columbaria var. columbaria. The phenolic contents of both parts of the plant were analyzed by LC-MS/MS. A total of 6 phenolic compounds were determined and chlorogenic acid was the major compound in both flower and leaf parts of the plants, with 5936.052 mg/g and 8021.666 mg/g, respectively. 6 different methods were used to determine the antioxidant activity of the plant parts. Both leaf and flower parts of the plant showed high antioxidant activity in all tested methods and the antioxidant activity values of the leaf part were measured higher than those of the flower part for four tests. The methanol extracts of the plant parts was analyzed with GC-MS and number of the essential oil compounds in the leaf and flower parts were determined as 17 and 13, respectively. Linalool compound was also found to be common in both parts of the plant. The major compounds of the essential oils were identified as 4Octadecenal (30.01%) in the flower and carvone (35.44%) in the leaf. In addition, terpene derivatives was determined as 90.32% of the highest essential oil group in the leaf, while this value was determined as 1.42% in the flower. For the flower, aromatics were determined as the main component group with 21.31%. (c) 2021 The Author. Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
AtıfWoS22OpenAlex29İncele - MakaleYalnız künye2021Scopus SJRQ4Chemical composition and biological activities of volatile oils of arabis alpina l. Ssp. alpina
Ucuncu, O.
This work reports volatile constituents, antimicrobial and antioxidant activity of volatile oils from the air-dried flower and aerial parts (APs) of Arabis alpina L. ssp. alpina. The volatile components of flower and aerial parts (stem + leaf) were investigated by means of hydrodistillation in Clevenger type apparatus and GC/MS/FID analysis. Fifty-one and fifty-three compounds in the volatile oils of flower and APs of A. alpina were identified. Terpene derivatives were the major volatiles in both oils. Hexahydrofarnesyl acetone was the main component of flower oil and APs oil in ratios of 16.27% and 26.94%, respectively. Additionally, both flower and APs essential oils were investigated for their antimicrobial activity against twelve bacteria and five fungi, using agar dilution method and antioxidant activities by using DPPH˙, ABTS˙+ and Folin-Ciocalteu assays. Flower oil was effective against B. subtilis and B. cereus even at 100µg/mL. The amount of total phenolic, %DPPH˙ scavenging activity and ABTS˙+ scavenging activity were found as 485.60±7.28 mg/mL GAE, 49.85±1.22% and 166.43±12.05µM Trolox equivalent, respectively. Flower oil exhibited antimicrobial effect against gram positive bacteria especially, and moderate antioxidant activity.
AtıfScopus3WoS2İncele - MakaleYalnız künye2021Scopus SJRQ2N epeta meyeri essential oil ameliorates fungal infection and the antioxidant response in grapevines (Vitis vinifera) infections by gray mold (Botrytis cinerea)
Karakuş, Sinem; Atici, Ökkeş; Köse, Cafer; Aydin, İhsan
The essential oil (EO) obtained from Nepeta meyeri Benth. used to struggle allelopathically with gray mold (Botrytis cinerea Pers.), which causes significant damage to vineyards (Vitis vinifera L. cv. Karaerik). The EO from N. meyeri was determined to contain 4aα, 7α, 7aα-nepetalactone (71.68%) at the highest rate when analyzed with GC/MS. Then, the doses (0.6, 0.8, and 1.0 µL/leaf) of 1 ppm EO solution were applied to the leaves together with the fungus inoculation (EO + F), as well as 1 day (EO + F1D) and 2 days (EO + F2D) before inoculation. The fungus application alone was evaluated as a control. Seven days after the inoculations, fungus development, lipid peroxidation level (as malondialdehyde), the contents of reactive oxygen species (ROS), photosynthetic pigments and soluble proteins, and the activities of antioxidant enzymes (superoxide dismutase, catalase, peroxidase, and glutathione reductase) were determined in the leaves. Findings revealed that EO + F1D among the applications and 1.0 µL/leaf among the EO doses significantly prevented fungus development on the leaf, compared to the control. Moreover, the same applications decreased ROS levels, such as H2O2 and O2·− and lipid peroxidation, while they increased antioxidant enzyme activities, as well as chlorophyll and soluble protein contents. Therefore, it can be suggested that the EO from N. meyeri has a potentially powerful usage as biofungicide in the allelopathic struggle against the infection of B. cinerea in vineyards.
AtıfScopus5WoS4OpenAlex6İncele - MakaleYalnız künye2021Scopus SJRQ1Single-step recovery of pectin and essential oil from lemon waste by ohmic heating assisted extraction/hydrodistillation: A multi-response optimization study
Tunç, Merve Tuğçe; Odabaş, Halil İbrahim
The main products obtained from citrus wastes are pectin and essential oil. In this work, ohmic heating assisted extraction/hydrodistillation (OHAE/H) was applied for the simultaneous recovery of pectin and essential oil from lemon waste. Optimum OHAE/H conditions to maximize the yield of pectin and essential oil were determined with response surface methodology. Three independent variables, namely liquid to solid ratio (w:v), extraction/hydrodistillation time (min) and voltage gradient (V/cm) were varied to obtain maximum pectin and essential oil yield. Optimum OHAE/H conditions were determined as 8.7:1 liquid to solid ratio, 58.4 min extraction/hydrodistillation time and 14.2 V/cm voltage gradient. The predicted pectin and essential oil yields at optimum conditions were 16.58 and 3.62 g/100 g lemon waste, respectively. Data analysis showed that all of the independent variables significantly affected the pectin and essential oil yield. In the verification study, close agreement was found between predicted and experimental values. Conventional heating extraction/hydrodistillation (CHE/H) were conducted to evaluate the effectivity of OHAE/H. With OHAE/H process, the yields of the pectin and essential oil were significantly increased when compared to CHE/H. Limonene concentration of the essential oil produced with OHAE/H was higher than the essential oil produced by CHE/H. Results demonstrate that the single-step OHAE/H could be an effective method for simultaneous extraction and hydrodistillation of pectin and essential oils.
AtıfScopus53WoS43OpenAlex54İncele - MakaleYalnız künye2019Scopus SJRQ1Ohmic heating assisted hydrodistillation of clove essential oil
Tunç, Merve Tuğçe; Koca, İlkay
Ohmic heating assisted hydrodistillation is a novel green technology for the extraction of essential oils. In this study, clove bud essential oils (CEO) were extracted by ohmic heating assisted hydrodistillation (OAHD) and compared with conventional hydrodistillation (HD) process, in terms of extraction yield, energy consumption and chemical properties. Ohmic heating assisted hydrodistillation process conditions were optimized by response surface methodology. Voltage gradient (7.5–12.5 V/cm, A), process time (30–120 minutes, B) and mass of clove bud (20–40 g, C) were varied in order to maximize CEO yield and to minimize energy consumption. Optimized extraction conditions were determined as, 12.5 V/cm voltage gradient, 97.967 min for process time and 40 g of mass of clove bud. Yield of CEO and energy consumption were found 13.18 ± 1.50% and 0.214 ± 0.030 kW h/g CEO at optimum extraction conditions, respectively. Under optimum conditions, both OAHD and HD methods were used for CEO extraction. Yields of CEO obtained by OAHD, HD-D (distilled water) and HD-S (salted water) were 13.18 ± 1.50, 8.23 ± 0.35 and 7.88 ± 0.60 respectively. Energy consumptions of OAHD and HD methods were not significantly different (P > 0.05). The main chemical component of CEO was eugenol and the yield of eugenol (g/100 g clove bud) was found higher with OAHD (6.95±0.6) method than HD-D (5.16 ± 0.20) and HD-S (5.13 ± 0.28). Antioxidant and antimicrobial properties of CEOs were investigated by FRAP, DPPH and disk diffusion method. Antioxidant properties of CEOs obtained by different extraction methods were not significantly different (P > 0.05) according to FRAP and DPPH analysis. Although inhibition zones of CEOs extracted with different methods were not significantly different (P > 0.05) for gram positive bacteria's, CEO obtained by OAHD and HD-D have significantly higher (P < 0.05) inhibition zones for K. pneumonia and E. coli, respectively. The results of this study showed that OAHD method is applicable for CEO production.
AtıfScopus87WoS66OpenAlex90İncele - MakaleAçık Erişim2019Scopus SJRQ2Volatile constituents and biological properties of essential oils from aerial parts of Gentiana gelida BIEB
Üçüncü, Osman; Karataş, Şeyda Merve; Baltacı, Cemalettin; Karaköse, Mustafa; Türkuçar, Semra Alkan
This work reports the chemical composition, antimicrobial and antioxidant activities of essential oils from the aerial parts of Gentiana gelida BIEB. for the first time in literature. The oils from the aerial parts (flower, leaf and stem) were obtained by Clevenger-type apparatus and characterized by GC-FID and GC-MS. While tricosane (21.67%) was the main component of flower oil, hexadecanoic acid was the most abundant component of leaf and stem oils in ratios 26.46% and 31.89%, respectively. Additionally, all essential oils of G. gelida were investigated for their antimicrobial activity against eight Gram negative bacteria, four Gram positive bacteria and five fungi, using agar dilution method and antioxidant activities by using 2,2-diphenyl-1-picrylhydrazyl radical scavenging and Folin-Ciocalteu assays. The flower oil of G. gelida showed stronger antimicrobial and antioxidant activities than those of stem and leaf. The amount of total phenolic content and scavenging activity of the flower oil were found 525.35±8.24 mg GAE/L and 49.30±1.25%, respectively.
AtıfScopus5WoS4OpenAlex4İncele - MakaleYalnız künye2017Chemical composition and bioactive properties of the essential oil of Rhinanthus angustifolius subsp grandiflorus
Kaya, A. A.; Üçüncü, O.; Ilter, S. M.; Baltaci, C.; Öztürk, S.
In this study, the chemical composition and antimicrobial activities of the essential oil of the Rhinanthus angustifolius subsp. grandiflorus plant were investigated. Essential oil was obtained from all parts of the plant by hydrodistillation and was analyzed by GC-FID and GC-MS. 31 components representing 99.46% of the total oils were characterized. The main components of these species were found to be 2,3-dihydro-5-methyl-1H-indene (25.14%), alpha-cubebene (19.27%), 1-hexadecene (15.59%) and hexadecanoic acid (12.14%). The antimicrobial activity of the isolated essential oil was investigated. Antimicrobial activity was observed against B. cereus, E. coli, E. coli O157:H7 and S. Aureus microorganisms. Moreover, an effect on the ferments of B. cereus, E. coli, E. coli O157:H7 and S. Aureus was detected.
AtıfWoS4İncele - MakaleYalnız künye2014Scopus SJRQ2Investigation of the possible use of black cumin (Nigella sativa L.) essential oil on butter stability; [Tereyaǧi{dotless} stabilitesi üzerine çörekotu (Nigella sativa L.) uçucu yaǧi{dotless} kullani{dotless}labilirliǧinin araşti{dotless}ri{dotless}lmasi{dotless}]
Çakmakçi, Songül; Gündoǧdu, Engin; Daǧdemir, Elif; Erdoǧan, Ümmügülsüm
The aim of this study was to investigate the effect of black cumin (Nigella sativa L.) essential oil on butter stability. For this aim, 0.05, 0.1 and 0.2 wt-% essential oil was added to the butter. Antioxidant activity of the essential oil was compared to that of synthetic antioxidant BHT (100 ppm). All samples were stored at 4±1°C for 90 days. Thiobarbituric acid and peroxide values of all samples containing essential oil were decreased depending on concentrations. The amount of 0.2% of essential oil had showed strong antioxidant activity, which was almost equal to that of BHT. The addition of essential oil reduced total aerobic mesophilic bacteria, lactic acid bacteria and coliform bacteria count during storage period but did not show remarkable antifungal activity. Samples containing essential oil were preferred by the panellists compared to Control sample. Present results indicate that black cumin essential oil may be considered as a new source of natural antioxidant.
AtıfScopus20WoS15OpenAlex6İncele - MakaleAçık Erişim2013Scopus SJRQ4Effect of some spice essential oils on the stability of frying oils
Tanriverdi, Ebru Sandal; Özcan, Mehmet Musa; Juhaimi, Fahad Al
In this study, peppers and potatoes were fried in olive and peanut oils. In order to evaluate the oxidative stability of frying oils, essential oils of sage, rosemary, thyme at the concentration of 0.3, 0.6, 0.9 and 1.2 %, separately and 0.01 % butylated hydroxytoluene were added into olive and peanut oils. Chemical properties of frying oils (free fatty acid %, peroxide value, DPPH, total phenolic and fatty acid composition) were determined after frying. Butylated hydroxytoluene showed the best effect on free fatty acid % and peroxide value of olive oils after frying of peppers and potatoes. Free fatty acid % values of frying oils of peppers and potatoes showed variation. The nearest values of oleic, linoleic and linolenic acid contents of frying olive oils of peppers and potatoes were determined with sample addition of butylated hydroxytoluene. Oleic, linoleic and linolenic acid contents of peanut oil with butylated hydroxytoluene and potato frying oil that addition of 0.3 % rosemary essential oil were determined to nearly the initial value of oil. These essential oils were also determined to show high radical scavenging effect. Rosemary essential oil was determined higher the radical scavenging effect and lower total phenolic compounds than thyme essential oils. There were not exact a relationship between radical scavenging effect and the amount of total phenolic compounds. The aim of current study is to establish to the effect of some spice essential oils on the stability of frying oils.
- MakaleYalnız künye2011Scopus SJRQ4Microwave assisted essential oil analysis and antimicrobial activity of M. alpestris subsp. alpestris
Cansu, Tayyibe Beyza; Yücel, Murat; Sinek, Kadriye; Baltaci, Cemalettin; Karaoglu, Sengül Alpay; Yayli, Nurettin
The present work describes the chemical composition and antimicrobial activity of the essential oil of Myosotis alpestris F.W. Schmidt subsp. alpestris (Boraginaceae). The essential oil was obtained from all parts of the plant by microwave distillation and analyzed by GCFID and GC-MS. Forty-seven components representing 88.2 % of the total oil were characterized and the main components of this species were found to be n-nonanal (11.8 %), decanal (10.8 %), n-octanal (10.7 %), hexahydrofanesyl acetone (6.6 %), o-cymene (3.9 %), tetradecanal (3.7 %), eicosanol (2.2 %) and E-β-farnesene (2.0 %). The isolated essential oils of M. alpestris subsp. alpestris was tested for antimicrobial activity against the bacteria Escherichia coli, Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes, Bacillus cereus, Mycobacterium smegmatis and the fungus Candida albicans and Saccharomyces cerevisiae at maximum essential oil concentration in hexane of 1000 μg/mL and they showed only antibacterial activity against fungus bacteria.
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