Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(67)
- Merdan, Mehmet(59)
- Duran, Celal(49)
- Ozdes, Duygu(46)
- Kaygusuz, Abdullah(45)
- Demir, Selim(37)
- Turan, Ibrahim(37)
- Karsli, Orhan(36)
- Öztürk, Serkan(35)
- Dokuz, Abdurrahman(34)
- Araz, Onur(32)
- Kandemir, Raif(31)
- Kulakaç, Nurşen(29)
- Sipahi, Ferkan(29)
- Arslan, Mehmet(27)
- Baltaci, Cemalettin(27)
- Baltacı, Cemalettin(27)
- Kurt, Kemal(27)
- Topal, Fevzi(27)
- Gücer, Mehmet Ali(25)
- Peker, Iskender(25)
- Aydin, Faruk(24)
- Bayrakdaroglu, Serdar(24)
- Maden, Nafiz(24)
- Ozturk, Samet(24)
- Vural, Alaaddin(24)
- Yolcu, Halil(24)
- Yücel, Cem(24)
- Aliyazicioglu, Yuksel(23)
- Kankal, Murat(23)
- Reis, Hatice Catal(23)
- Ürkek, Bayram(23)
- Günen, Mehmet Akif(22)
- Kurnaz, Muammer(22)
- Topal, Meryem(22)
- Karimullah, Suud Sarim(21)
- Uysal, Ibrahim(21)
- Ashyralyyev, Charyyar(20)
- Aydin, Aydanur(20)
- Bayraktar, Alemdar(20)
Yayınlar
- MakaleAçık Erişim2021Scopus SJRQ1Non-Invasive Monitoring of Ethanol and Methanol Levels in Grape-Derived Pisco Distillate by Vibrational Spectroscopy
Menevseoglu, Ahmed; Aykas, Didem P.; Hatta-Sakoda, Beatriz; Toledo-Herrera, Victor Hugo; Rodriguez-Saona, Luis E.
Handheld Raman and portable FT-IR spectroscopy devices were evaluated for fast and non-invasive determination of methanol and ethanol levels in Peruvian Pisco. Commercial Peruvian Pisco (n = 171) samples were kindly provided by the UNALM Alliance for Research in Alcohol and its Derivatives (Lima, Peru) and supplemented by purchases at grocery and online stores. Pisco spectra were collected on handheld Raman spectrometers equipped with either a 1064 nm or a 785 nm excitation laser and a portable infrared unit operating in transmission mode. The alcohol levels were determined by GC-MS. Calibration models used partial least-squares regression (PLSR) to develop prediction algorithms. GC-MS data revealed that 10% of Pisco samples had ethanol levels lower than 38%, indicating possible water dilution. Methanol levels ranged from 10 to 130 mg/100 mL, well below the maximum levels allowed for fruit brandies. Handheld Raman equipped with a 1064 nm excitation laser gave the best results for determining ethanol (SEP = 1.2%; RPre = 0.95) and methanol (SEP = 1.8 mg/100 mL; RPre = 0.93). Randomly selected Pisco samples were spiked with methanol (75 to 2800 mg/100 mL), and their Raman spectra were collected through their genuine commercial bottles. The prediction models gave an excellent performance (SEP = 98 mg/100 mL; RPre = 0.97), allowing for the non-destructive and non-contact determination of methanol and ethanol concentrations without opening the bottles.
AtıfScopus19WoS17OpenAlex21
İncele - MakaleYalnız künye2021Scopus SJRQ2Non-targeted approach to detect green pea and peanut adulteration in pistachio by using portable FT-IR, and UV-Vis spectroscopy
Menevseoglu, Ahmed; Aykas, Didem Peren; Adal, Eda
Pistachio is one of the most expensive nuts with having high economic importance in Turkey. It has become more prone to adulteration because of its high commodity value. Peanut with color additives and green pea are generally used to adulterate ground pistachio. Vibrational spectroscopy is a potential technique to detect adulterations in pistachio. The objective of this study was to generate a non-targeted method for portable FT-IR and UV-Vis spectrometers to authenticate pistachio and detect green pea and peanut adulterations. Pistachio granules were adulterated with green pea and peanut at different concentrations (5 to 40% w/w). Spectra were collected by a portable FT-IR spectrometer and by a conventional UV-Vis spectrometer and analyzed by Soft Independent Modeling of Class Analogy (SIMCA) to generate classification algorithms to authenticate pistachio, and Partial Least Square Regression (PLSR) to predict the concentrations of adulterants. SIMCA showed very distinct clusters for pure samples. Moreover, adulterated pistachio samples were discriminated by SIMCA even in low levels of adulteration (5%). Portable FTIR showed excellent performance (r(val) > 0.93) of predicting the adulterant levels with a standard error of prediction (SEP) 0.66% and 0.80% for green pea and peanut, respectively. Similarly, UV-VIS predicted (r(val) > 0.93) the adulterant levels with SEP 0.58% and 0.14% for green pea and peanut, respectively. The results supported that portable FT-IR, and UV-Vis units present great potential for real-time surveillance of green pea and peanut adulteration in pistachio.
AtıfScopus13WoS12OpenAlex15İncele - MakaleAçık Erişim2021Scopus SJRQ2Role of the Health System in Combating Covid-19: Cross-Section Analysis and Artificial Neural Network Simulation for 124 Country Cases
Bayraktar, Yuksel; Özyilmaz, Ayfer; Toprak, Metin; Isik, Esme; Büyükakin, Figen; Olgun, Mehmet Firat
In the fight against Covid-19, developed countries and developing countries diverge in success. This drew attention to the discussion of how different health systems and different levels of health spending are effective in combating Covid-19. In this study, the role of the health system in the fight against Covid-19 is discussed. In this context, the number of hospital beds, the number of doctors, life expectancy at 60, universal health service and the share of health expenditures in GDP were used as health indicators. In the study, firstly 2020 data was estimated by using the Artificial Neural Networks simulation method and this year was used in the analysis. The model, with the data of 124 countries, was estimated using the cross-sectional OLS regression method. The estimation results show that the number of hospital beds, number of doctors and life expectancy at the age of 60 have statistically significant and positive effects on the ratio of Covid-19 recovered/cases. Universal health service and share of health expenditures in GDP are not significant statistically on the cases and recovered. Hospital bed capacity is the most effective variable on the recovered/case ratio.
AtıfScopus17WoS17OpenAlex20İncele - MakaleAçık Erişim2021Scopus SJRQ2Adipokine, gut and thyroid hormone responses to probiotic application in chukar partridges (Alectoris chukar) exposed to heat stress
Bayraktar, Bulent; Tekce, Emre; Kaya, Hacer; Gürbüz, Ahmet Burak; Dirican, Ebubekir; Korkmaz, Serol; Atalay, Banu; Ülker, Ufuk
The aim of this study was to investigate the effect of Lactobacillus reuteri E81 (LRE) probiotic supplementation on heat stress responses in chukar partridges (Alectoris chukar). The birds were divided into two groups, one of which was exposed to heat stress (HS). Within each group, four subgroups, each including 64 birds, were created for the three treatment doses (200, 400 or 600 mg/kg) of LRE and the control. The experiment was started with day-old birds, kept at a temperature of 25 degrees C or 37 degrees C. After a 7-day adjustment period, the LRE supplementation lasted for 35 days. The levels of different adipokines, including visfatin (VF), adiponectin (ADP), chemerin (CHEM), as well as the concentration of plasma citrulline (CIT) and the levels of thyroid hormones (T3 and T4) and thyroid-stimulating hormone (TSH) in the blood were measured at 21 and 42 days of age. A significant correlation (P < 0.01) was found between LRE supplementation and the decrease in serum VF, ADP, CIT, T3 and T4 levels in partridges exposed to HS. On the other hand, no significant relationship was found between LRE supplementation and the serum CHEM and TSH levels (P > 0.05). We concluded that the addition of 600 mg/kg LRE is beneficial in preventing intestinal damage and inflammation provoked by HS.
AtıfScopus13WoS14OpenAlex16İncele - MakaleAçık Erişim2020The Mediating Role of Employee Sacrifice in the Effect of Managerial Morality on Employees' Perspectives on Their Colleagues
Durmus, Ibrahim
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- MakaleYalnız künye2020The Effect of Brand Personality on Sport Team Identification
Bayrakdaroglu, Yesim
This study examined the perception levels of brand personalities and team identification of Gumushanespor spectators, and also analyzed the data in terms of various variables. The participants of this study consisted of a total of 326 spectators (166 female and 160 male) living in the center of Gumushane, Turkey. As data collection tools Sport Spectator Identification Scale and Brand Personality Scale were used. In the analysis of the data, Single Factor Variance Analysis, Correlation Analysis, and Multiple Linear Regression Analysis were used for variables determined to show normal distribution and homogeneity. On the other hand, Kruskal-Wallis Test was applied to the data that could not provide the parametric test condition. Tukey Test was used in Variance analysis, and Mann Whitney U Test was used in the Kruskal-Wallis Test for multiple comparison processes. Findings were obtained in terms of various variables in the analyzes. In addition, the results of the analysis indicated that the brand personality is a significant and powerful predictor of identifying with the team with the sub-dimensions of excitement and sophistication. However, sincerity, competence, and ruggedness variables that make up the brand personality did not make a significant contribution to this predictive model.
AtıfWoS1İncele - MakaleYalnız künye2020GRAMMAR TERMS OF TURKMEN TURKIC
Gökçür, Engin
Turkmen Turkic is in the south-west branch of the Turkic language family. Gagauz and Turkey Turkish constitute the western branch of the south-western Turkic while Azerbaijan and Turkmen Turkic constitute the eastern branch. The Turkmen Turks, which were under the rule of the Union of the Soviet Socialist Republics from 1884 to 1991, gained their independence in 1991 with the dissolution of the Soviet Union. In Turkmenistan, which was under the rule of the Soviet Union for a while, the influence of Russian Turcology on the language studies on Turkmen Turkic is in question. Therefore, some grammar topics in Turkmen Turkic are dealt in a different way from Turkey Turkish. The density of Turkish words is prominent in the formation of grammatical terms in Turkmen Turkic. Because grammar studies have been dealt according to Russian Turcology for a long time, some of the terms have been taken especially from Russian and and these terms have been used like this for a long time. In this study, around 760 grammatical terms in Turkmen Turkic were determined. For the determination of these terms, dictionaries and grammar works prepared on Turkmen Turkic were used. The works that are used in this study are given in the bibliography.
- MakaleYalnız künye2020Scopus SJRQ4Betting on the Future: A Comparison Macroeconomic Dynamics of Labour Income Share in The United States: Evidence From MARS
Çelik, Orkun
Macroeconomic dynamics of the labour income share (herein: lis) in the United States for the period of 1948Q1-2019Q1 are tried to be determined in this study, where the Multivariate Adaptive Regression Splines (will be referred to herein as MARS) approach is employed. In order to investigate sectorial differences, the business, non-farm, and non-finance sectors are evaluated, respectively. In accordance with the results obtained, it may be observed that the macroeconomic dynamics of lis in the business sector are productivity, export, profit, gross private domestic investment, unemployment rate, current account balance, gross domestic product, and tax revenue, respectively. Related macroeconomic dynamics of lis concerning non-farm sector are productivity, current account balance, gross private domestic investment, export, consumer price index, gross domestic product, profit, unemployment rate, and gross government investment.
- MakaleAçık Erişim2020The Effect of Satisfaction of Basic Psychological Needs on Sporting Behavior in Physical Education
Turkay, Hikmet
In order to examine the basic psychological needs of the students, 372 students studying in secondary schools were selected. In the research, it was found that there were differences between the students according to age, gender, participation in out-of-school activities, and social identification variables. As a result, it can be said that there was a relationship between the satisfaction of basic psychological needs of individuals and sporting behaviour in physical education.
- MakaleYalnız künye2020The Effect of Remittances on Financial Development in Developing Countries: Dynamic Panel Data Analysis
Akbulut Yildiz, Gizem
The aim of the study is to measure the effect of workers' remittances on financial development. The study on 44 developing countries covers the period 1994-2017. In the empirical analysis of the study, financial development index data was used as the dependent variable. However, financial institutions and financial markets index data, which are the sub-criteria of the index, are also used in the study as dependent variables. As independent variables, workers' remittances, GDP per capita, trade openness and inflation data are used. According to the results of the analysis made using the Two-Stage System Generalized Moments Method, workers' remittances, per capita GDP and trade openness, financial development, financial institutions and financial markets are statistically significant and positive, while inflation is negatively.
- MakaleAçık Erişim2020Modern Man in Techno-Scientific Progressivism and Nostalgic-Developmentalism Dilemma
Demir, Sertac Timur
This article interrogates the human crisis of the modern age with a comparative and synthesist approach. Indeed, in the hands of techno-scientific progressivism that has been accelerated since the industrial revolution and the nostalgic-developmentalism that is provoked by the progressivism, the central issue in crisis is not humanity; but man himself. Moreover, this crisis, which encircles daily life entirely, is not merely epistemological, also ontological. Perhaps the most valid question of the day for the modern individual who is torn between techno-scientific progressivism that glorifies speed, technique, method, invention and externality, and the doctrines of nostalgicaldevelopmentalism that prioritise the past, memory, mystical orientation and internality, is perhaps to remain human. While Stanley Kubrick's 2001: A Space Odyssey (1968), one of the two philosophical films subject to analysis in the article, refers to such a progressivism; and Andrei Tarkovsky's Solaris (1972) visualises developmentalism. Beyond a science-fiction analysis, this study, which approaches both positions critically, aims to focus on the crucial questions that become evident in the films with the answers of significant thinkers such as Paul Chesterton, Gaston Bachelard, Gunther Anders, Ivan Illich, Lewis Mumford, Zygmunt Bauman and Y. Noah Harari. Besides, as a proposition, it can be stated that today sci-fi movies -even the most extraordinary ones- have ironically turned into one of the most authentic projectors in making sense of the fantastic world we live in.
AtıfOpenAlex2
İncele - MakaleAçık Erişim2020Criticism of Kant's Conception of Freedom in Adorno
Tüzen, Muhammed Ahmet
Adorno, who has critical thoughts on the positivist perspective that is the core of the philosophy of Enlightenment and the mental comprehension to which positivism depends, states that Kant's notion of freedom, which puts strictly adhesion to the law in the center, is an abstract, disconnected from experience, compelling/oppressive nature. Accordingly, Kant, who activates the mind against the blind power of nature, explains the free action as to act according to the pure mind. In Kant, which approaches moral laws as freedom laws, freedom is considered as the law that both is to use of the mind in an absolute manner and must be obeyed and treated accordingly. In this context, Adorno implies that Kant's moral philosophy is structured in such a way as not to allow it to act otherwise, although it does not have authoritarian thoughts. This study which is based on Adorno's thoughts aims to evaluate Kant's understanding of freedom in four parts within the above-mentioned framework: (i) Freedom as a balancing force against the causality of nature, (ii) freedom disconnected from experience and spiritualized, (iii) freedom to express action by centering the law, (iv) freedom intertwined with bourgeois work ethic.
AtıfTR Dizin1İncele - MakaleYalnız künye2020The Effect of Defense Sports on the Treatment of Attention-Deficit/Hyperactivity Disorder in Children
Bayrakdaroglu, Serdar; Tekin, Ali
Attention-deficit/hyperactivity disorder is a significant problem in children. Primarily pharmacological, educational, cognitive-behavioural and multi-model intervention techniques are used to treat this disorder. The success level differs with advantages and disadvantages of each technique and any single technique is not sufficient. In recent years, the positive aspects of physical exercise used in treatment alone or in combination with other techniques has made the different types of physical exercise worthy of investigation. This review aims to summarize the scientific evidence obtained through literature on the effects of defense sports in the treatment of attention-deficit/hyperactivity disorder in children. The results showed that the most beneficial sports are Taekwondo, Karate, Judo and Tai Chi. There are studies supporting the positive effect of the use of defense sports in treatment with few exceptions, but it is quantitatively insufficient. Therefore, new studies are needed to test the effect of different defense sports on a sufficient number of different samples representing the related population.
AtıfWoS1İncele - MakaleYalnız künye2020The Effects of Explosive Strength Applied to Footballers on Some Physical and Physiological Parameters
Zambak, Omer; Sever, M. Onur
It is aimed to investigate the effects of explosive strength training on aerobic capacity, anaerobic capacity, blood pressure, resting heart rate and shooting speed. The aim of this study was to investigate the explosive strength training on some physical and physiological parameters. The study included 38 volunteer 1st and 2nd amateur league footballers aged 1825 years. Aerobic capacities of the players were measured by shuttle run test and Anaerobic power measurement by vertical jump test. After calculating the vertical jump value of the athletes anaerobic strength; calculated using the Lewis Nomogram using vertical jump and body weight values. The shooting speed of the players was determined by speed pocket radar equipment In the study, different strength training (station training method) and football-specific technical and tactical training programs were applied to the research group for 8 weeks, 3 days a week. only technical and tactical training programs were applied to the control group. The parameters were taken twice before and after the 8-week study. In order to determine the differences between the pre-test and post-test results, The Wilcoxon test, one of the nonparametric tests, was used to, Mann Whitney U-test analysis was used to compare the pre-test and post-test values between the groups. The significance level of the study was accepted as p<0.05. Significant difference in shooting speed was found as a result of the signed ranks test comparing the pre-test and post-test measurements of the research group participants (p<0,05). Significant differences between the measurements of aerobic power, anaerobic power were found as a result of the signed ranks test comparing the pre-test and post-test values of the control group participants (p<0,05). After the Mann-Whitney U test, where the posttest measurement values of the experimental and control group participants were compared, there was a significant difference between the groups in aerobic power values, and this difference was found to be in favor of the experimental group participants (p <0.05). As a result, it can be said that explosive strength training applied to amateur football players between the ages of 18 - 25 increases the shooting speed.
AtıfWoS1İncele - MakaleYalnız künye2020Scopus SJRQ4Hepatic venous Doppler assessment can anticipate simplified pulmonary embolism severity index and right ventricle dysfunction in patients with acute pulmonary embolism
Acar, Emrah; Izci, Servet; Inanir, Mehmet; Yilmaz, Mehmet F.; Izgi, Ibrahim A.; Gokce, Mustafa; Kirma, Cevat
Purpose Acute pulmonary embolism (APE) is a life-threating cardiothoracic thromboembolic emergency in which right ventricle dysfunction (RVD) is a major concern. In the present study, we examined the hepatic veins (HVs) blood flow with pulsed-wave spectral Doppler ultrasonography to determine its relationship with the simplified pulmonary embolism severity index (sPESI) and the patient's RVD status. Methods We divided the 243 patients who met the inclusion criteria into two groups based on both their sPESI scores and their RVD status. Transthoracic echocardiography was performed to evaluate the RVD and the HVs within 1 hour after patient admission. The liver was evaluated using subcostal and intercostal echocardiographic windows in grayscale B-mode, and HVs were assessed using color and spectral Doppler assessment though the same echocardiographic windows. Result A cut-off value of the systolic reverse flow velocity-time integral (SrVTI) = 2.2 cm carried a sensitivity and specificity of 84.29% and 74.89%, respectively, for the prediction of sPESI >= 1. A SrVTI cut-off value of 2.1 cm yielded a sensitivity and specificity of 83.03% and 73.91%, respectively, for the prediction of RVD. Conclusion HV Doppler assessment could be a useful method for anticipating the sPESI and the presence of RVD in patients with APE. In addition, it may provide information regarding the hemodynamic impact of APE.
AtıfWoS3OpenAlex3İncele - MakaleAçık Erişim2020Scopus SJRQ4Investigation of Fosfomycin and Chloramphenicol Susceptibility of Carbapenemase-Producing Klebsiella pneumoniae Strains
Borsa, Baris Ata; Güngördü-Dalar, Zeynep; Karakullukçu, Asiye; Özalp, Veli Cengiz; Aygün, Gokhan
Objective: Antimicrobial resistance is one of the most mportant health problems of recent years. Multidrug-resistant Klebsiella pneumoniae strains have been causing serious problems in many countries including Turkey in recent years. Aim of this study was to detect molecular mechanisms behind the carbapenem resistance in carbapenem-resistant K. pneurnoniae strains isolated from rectal swab samples and investigate the susceptibility of two potentially alternative drugs, fosfornycin, and chloramphenicol. Methods: 46 K. pneumoniae strains isolated from rectal screening cultures of intensive care unit patients by using MacConkey agar containing 2 mg/L meropenem were included in this study. Carbapenem resistance of strains were confirmed by minimum inhibitor concentrations of meropenem obtained with gradient strip test. Presence of the bla(KPC,) bla(NDM) and bla(OXA), bla(IMP) and bla(VIM) genes were investigated by the real-time polymerase chain reaction. Broth microdilution method was used to investigate chloramphenicol susceptibility, and gradient strip test was used to investigate fosfomycin susceptibility of the strains. Results: At least one carbapenemase gene was detected in all K. pneumoniae strains. While all strains were found positive for the presence of OXA-48 type carbapenemase gene, 12 (26%) out of 46 were positive for both OXA-48 and NDM-1 carbapenemase genes, and only one (2%) strain was positive for OXA-48, NDM-1, and IMP-1 carbapenemase genes. Only 3 (6%) out of 46 strains were found susceptible to fosfomycin while 23 (50%) of them were susceptible to chloramphenicol. Additionally, we observed that the resistance rates to fosfomycin and chloamphenicol tended to be higher among carbapenemase producers. Conclusions: It is estimated that fosfomycin is not going to be a good option for the treatment of infections caused by carbapenemresistant K. pneumoniae strains in Turkey since only 6% of them were susceptible. Although the chloramphenicol susceptibility rate (50%) was higher than fosfomycin, further clinical studies are required to provide a better knowledge about the usage of this antibiotic in systemic infections. Moreover, multiple carbapenemase producers tended to be more resistant to fosfomycin and also chloramphenicol.
- MakaleAçık Erişim2020The Ameliorative Effects of Ethyl Pyruvate and Dimethyl Sulfoxide on Ischemic Tissue Injury in Experimental Carbon Monoxide Intoxication
Pasli, Sinan; Imamoglu, Melih; Çiçek, Mustafa; Yadigaroglu, Metin; Sahin, Aynur; Karaca, Yunus; Yulug, Esin; Tatli, Ozgur
Aim: The purpose of this study was to investigate the protective effects of ethyl pyruvate (EP) and dimethyl sulfoxide (DMSO) on ischemic tissue in brain and cardiac and hepatic tissues in experimentally induced carbon monoxide (CO) intoxication. Material and Methods: Thirty-five mature female Sprague Dawley rats were randomized into five groups of seven animals each. Group 1 received no CO or treatment. Rats in groups 2, 3, 4 and 5 were made to inhale a high-concentration 5000 ppm CO gas mixture for 60 min at 4 L/min. CO levels were then measured from 1 mL tail vein blood. Group 2 received no therapeutic agent, group 3 received 6 mg/kg intraperitoneal (ip) DMSO, group 4 received 50 mg/kg ip EP, group 5 received 50 mg/kg EP and 6 mg/kg DMSO ip. All rats were sacrificed by decapitation. Brain, cardiac and hepatic tissues were removed and histopathological scores were compared. Results: Comparison of group 2 with group 3 and group 2 with group 5 revealed that DMSO alone and EP + DMSO exhibited a reducing effect on degree of cerebral neuronal alteration, degenerative neuron rates, and total cardiac injury score (p=0.005, p=0.002, p=0.004 and p=0.002, p=0.001, p=0.004 respectively). There was no histopathological difference between group 2 and group 4 suggesting EP alone had no therapeutic effect on histopathological injury. Conclusion: Based on our study findings, EP administered alone exhibited no protective effects on the organ injuries investigated, while DMSO exhibited reducing effects on degree of neuron alteration, rates of degenerative neurons, and total cardiac injury scores. An ameliorating effect on cardiac and hepatic injury was more prominent with combined treatment.
- MakaleAçık Erişim2020Scopus SJRQ1Air pollution, a possible risk factor for multiple sclerosis
Börü, Ulku Turk; Bölük, Cem; Tasdemir, Mustafa; Gezer, Tugce; Serim, Vedat Ataman
Objective Studies focusing attention on the effects of environmental pollution on the etiology of multiple sclerosis (MS) are on the increase. The aim of this study was to determine MS prevalence in a city home to an iron and steel factory which causes air pollution. Methods The study was designed as a cross-sectional, population-based, descriptive epidemiologic study. Eregli city, which has an iron and steel factory and proven air pollution, was screened. Additionally, Devrek city, which is a rural and clean city, located 40 km away from Eregli was assigned and results were compared. A validated questionnaire was used for screening. McDonald 2010 criteria were used to diagnose cases. Results 32 261 people were screened in Eregli, and 21 963 people were screened in Devrek. In total, 41 patients were diagnosed with clinical definite MS. Crude prevalence was found to be 96.1/100 000 in Eregli and 45.5/100 000 in Devrek. The mean age of patients was 39.8, and the female/male ratio was 1.9. Conclusion The results of this study indicate a more than double MS prevalence rate in the area home to an iron and steel factory when compared to the rural city. This supports the hypothesis that air pollution may be a possible etiological factor in MS.
AtıfWoS29OpenAlex38İncele - MakaleYalnız künye2020Scopus SJRQ3Right Ventricular Early Inflow-Outflow Index-A new method for echocardiographic evaluation of right ventricle dysfunction in acute pulmonary embolism
Acar, Emrah; Izci, Servet; Inanir, Mehmet; Yilmaz, Mehmet Fatih; Izgi, Ibrahim Akin; Kirma, Cevat
Introduction Acute pulmonary embolism (APE) is a cardiothoracic thromboembolic emergency at risk of life-threatening. Several risk graduation algorithms may be applied to delineate short-term mortality in patients with APE. In this study, we aim to depict the relationship between the right ventricular early inflow-outflow (RVEIO) index, which is a Doppler-based parameter, and the pulmonary embolism severity index(PESI) in acute pulmonary embolism. Methods In the presented study, a total of 160 patients who were diagnosed with APE using pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were comprised. Patients were separated to 2 groups based on the simplified PESI (sPESI): sPESI < 1 (n = 88) and sPESI >= 1 (n = 72). Echocardiographic parameters, including the RVEIO index, were measured. Results There were no significant differences between the groups in age and gender distribution, or the presence of diabetes mellitus, hypertension, smoking, and history of coronary artery disease. There was a positive correlation with the mortality rate and RVEIO index; the mortality was higher in patients with a higher RVEIO index(<0.001). In receiver operating characteristic (ROC) curve analysis using a cutoff level of 14.39, RVEIO index predicted mortality with a sensitivity of 80.4% and specificity of 57.6%(ROC area under curve:0.694; 95%CI, 0.581-0.814; P < .001). RVEIO index was higher in the sPESI >= 1(n:72) than in the patients with sPESI < 1(14.27 +/- 2.13 vs 10.63 +/- 2.09; P < .001). There was a positive correlation between RVEIO index and sPESI score(+0.428; P < .001). Conclusion As well as predicting the degree of tricuspid regurgitation (TR), the RVEIO index is well-correlated with sPESI score and is associated with mortality in patients with APE. This easily measurable parameter may be used to predict short-term mortality in APE patients.
AtıfWoS4İncele - MakaleYalnız künye2020Scopus SJRQ3Potential therapeutic effects of ethyl pyruvate and N-acetyl cysteine in an experimental rat model of corrosive esophageal
Tatli, Ozgur; Pasli, Sinan; Imamoglu, Melih; Cicek, Mustafa; Yadigaroglu, Metin; Sahin, Aynur; Dilaver, Irem; Yulug, Esin; Karaca, Yunus
Background and study aims: Esophageal burns due to ingestion of corrosive substances are frequently seen in both children and adults. However, there is no standard method of treatment to prevent associated mortality and morbidity. Therefore, this study aimed to evaluate the effects of known antioxidants, namely N-acetyl cysteine and ethyl pyruvate, on esophageal damage due to sodium hydroxide-induced corrosive burns. Materials and methods: Thirty-five female rats were randomly assigned to five equal groups. Group 1 was the sham group, while Group 2 was the control group. Group 3 received N-acetyl cysteine, Group 4 received ethyl pyruvate, and Group 5 received both N-acetyl cysteine and ethyl pyruvate. Rats in the burn groups were gavage-fed with 0.2mL of 25% NaOH. All esophagi were extracted on day 4 for histopathological evaluation. Results: Total histopathological damage scores were evaluated at the end of the study. Groups 3 and 5 were significantly different from the control group in terms of total histopathological scores (p = 0.001), while no significant difference was seen with Group 4. Stenosis index results in groups 3 and 5 were similar to those seen with total histopathological scores (p = 0.004). Conclusion: N-acetyl cysteine, alone or in combination with ethyl pyruvate, may be useful in the treatment of esophageal damage associated with corrosive substances and in achieving histopathological improvement in an experimental setting. (C) 2020 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved.
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