Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Uzun, Sevda(67)
- Merdan, Mehmet(59)
- Duran, Celal(49)
- Ozdes, Duygu(46)
- Kaygusuz, Abdullah(45)
- Demir, Selim(37)
- Turan, Ibrahim(37)
- Karsli, Orhan(36)
- Öztürk, Serkan(35)
- Dokuz, Abdurrahman(34)
- Araz, Onur(32)
- Kandemir, Raif(31)
- Kulakaç, Nurşen(29)
- Sipahi, Ferkan(29)
- Arslan, Mehmet(27)
- Baltaci, Cemalettin(27)
- Baltacı, Cemalettin(27)
- Kurt, Kemal(27)
- Topal, Fevzi(27)
- Gücer, Mehmet Ali(25)
- Peker, Iskender(25)
- Aydin, Faruk(24)
- Bayrakdaroglu, Serdar(24)
- Maden, Nafiz(24)
- Ozturk, Samet(24)
- Vural, Alaaddin(24)
- Yolcu, Halil(24)
- Yücel, Cem(24)
- Aliyazicioglu, Yuksel(23)
- Kankal, Murat(23)
- Reis, Hatice Catal(23)
- Ürkek, Bayram(23)
- Günen, Mehmet Akif(22)
- Kurnaz, Muammer(22)
- Topal, Meryem(22)
- Karimullah, Suud Sarim(21)
- Uysal, Ibrahim(21)
- Ashyralyyev, Charyyar(20)
- Aydin, Aydanur(20)
- Bayraktar, Alemdar(20)
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ2Screening of Chemical Profile by LC–MS/MS and Assessment of Biological Properties of Achillea sintenisii Hub. Mor. From Turkey
Köksal, Ekrem; Altay, Ahmet; Altın, Sevgi; Alp, Cemalettin; Ulutaş, Yakup; Şimşek, Samed; Karakuş, Sinem; Akyüz, Sümeyye; Aygül, İmdat; Akşit, Hüseyin
The aim of this study was to determine the secondary metabolites of the n-hexane, ethyl acetate, methanol, and water extracts of Achillea sintenisii Hub. Mor. and to ascertain their divergent biological properties. LC–MS/MS analysis was performed to identify the bioactive compounds. The anticancer properties of the samples were tested against human breast (MCF-7 and MDA-MB-453) and colon (HT-29) cancer cell lines by XTT assay. The anti-Alzheimer's studies were performed using Ellman's assay. The antimicrobial studies were carried out by Kirby–Bauer disc diffusion method. The antioxidative potential of the samples was evaluated on the basis of 2,2-diphenyl-1-picrylhydrazyl scavenging and ferric reducing antioxidant power assays, LC–MS/MS analysis revealed 27 phytochemicals, including high concentrations of quinic acid, gentisic acid, chlorogenic acid, luteolin, cynaroside, and caffeic acid. Ethyl acetate extract exhibited the most potent cytoxicity against MDA-MB-453 cells, with an IC50 value of 83.05 µg/mL. All extracts showed stronger inhibitory activity against acetylcholinesterase and butyrylcholinesterase compared to tacrine. The n-hexane, ethyl acetate, and methanol extracts exhibited considerable antimicrobial activity against Enterococcus faecalis, approaching the level of vancomycin. Methanol extract possessed the highest DPPH scavenging and ferric reducing antioxidant power. These findings render A, sintenisii a promising source for the pharmaceutical, cosmetic, and food industries.
AtıfScopus10WoS8OpenAlex11İncele
- MakaleAçık Erişim2025Scopus SJRQ2The Analysis of Three-Dimensional Time-Fractional Helmholtz Model Using a New İterative Method
Şahin, Yasin; Merdan, Mehmet; Açıkgöz, Pınar
This paper proposes a novel analytical method to address the Helmholtz fractional differential equation by combining the Aboodh transform with the Adomian Decomposition Method, resulting in the Aboodh–Adomian Decomposition Method (A-ADM). Fractional differential equations offer a comprehensive framework for describing intricate physical processes, including memory effects and anomalous diffusion. This work employs the Caputo–Fabrizio fractional derivative, defined by a non-singular exponential kernel, to more precisely capture these non-local effects. The classical Helmholtz equation, pivotal in acoustics, electromagnetics, and quantum physics, is extended to the fractional domain. Following the exposition of fundamental concepts and characteristics of fractional calculus and the Aboodh transform, the suggested A-ADM is employed to derive the analytical solution of the fractional Helmholtz equation. The method’s validity and efficiency are evidenced by comparisons of analytical and approximation solutions. The findings validate that A-ADM is a proficient and methodical approach for addressing fractional differential equations that incorporate Caputo–Fabrizio derivatives.
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- MakaleYalnız künye2025Scopus SJRQ1Effectiveness of psychosocial interventions in eating disorders: A meta-analysis study
Bayrak, Nurten Gülsüm; Uzun, Sevda
Background: Psychosocial interventions are an essential component in the treatment of eating disorders that can negatively affect both mental and physical health. Aims: This study was conducted to determine the effect size of psychosocial interventions in eating disorders. Methods: For this meta-analysis study, researches were obtained by searching PubMed, Web of Science, EBSCO host, Google Scholar, and YÖK Thesis Centre databases in August to September 2024 without any year limitation. After the reviews, 15 studies were included. The data were synthesized by meta-analysis and narrative methods. Results: In this meta-analysis, psychosocial interventions in eating disorders were found to improve depression (SMD = −0.371, 95% CI [−0.697, −0.045]; Z = −2.228, p = .026); stress (SMD = −0.545, 95% CI [−1.080, −0.011]; Z = −1.999, p = .046); self-control (SMD = 0.476, 95% CI [0.116, 0.835]; Z = 2.594, p = .009); and emotional eating (SMD = 0.224, 95% CI [−4.305, −0.164]; Z = −2.115, p = .034). Discussion: The results of the study showed that psychosocial interventions in eating disorders are effective in disease symptoms (depression, stress, self-control, and emotional eating). In addition to psychopharmacological treatment, psychosocial interventions should be included in the treatment of eating disorders.
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- MakaleAçık Erişim2025Scopus SJRQ4Are Women of Reproductive Age Aware of Gynecological Cancers?
Ketenciler, Aysun Perim; Metinoğlu, Meryem; Karakaş, Sevda; Göncü, Gülin
Objective: This descriptive study aimed to determine the awareness levels of women of reproductive age regarding gynecological cancers. Methods: The study was conducted with 379 women aged between 15 and 49 registered at two separate Family Health Centers in Tekirdağ city center between May 2022 and April 2023. Data were collected using the "Gynecological Cancers Awareness Scale" and an "Introductory Information Form." Descriptive statistics including number, minimum, maximum, percentage, mean, and standard deviation were provided using the SPSS 21 package program. Shapiro-Wilk normality test, Independent Sample T-test, One Way ANOVA, Pearson correlation test, and Bonferroni test were used for data analysis. A statistical significance level of p <0.05 was accepted. Results: The mean age of the women in the study was 34 ±11 years, with 61.5% being married. The average Gynecological Cancers Awareness Scale (GCAS) score was 157.1 ±17.1 (range 106-205). Sub-dimension scores were: "Early Diagnosis and Information Awareness" 17.1 ±2.3 (range 10-20), "Risk Awareness" 28.4 ±5.3 (range 13-45), "Prevention Awareness" 22.4 ±3.4 (range 12-30), and "Routine Checks and Serious Illness Perception" 89.0 ±11.9 (range 45-110). In the study, 48.5% of the women knew about early diagnosis methods for gynecological cancers, and 76% were aware of the Cancer Early Diagnosis Screening and Education Center (KETEM). Women who were aware of risky health behaviors and cancer symptoms had higher awareness levels (p <0.05). There was no significant difference between the number of pregnancies and births and awareness levels (p >0.05). Conclusion: The result shows that women have a moderate level of awareness about gynecological cancers; however, their knowledge of gynecological cancer symptoms and awareness of risky health behaviors is higher. Additionally, more than half of the participants (60.7%) have never had a gynecological examination.
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- MakaleAçık Erişim2025Scopus SJRQ1Combined innovative trend analysis methods for seasonal trend testing
Şan, Murat
While holistic trend identification is essential, it does not consider the periodic, e.g., monthly, trend characteristics needed to identify seasonal trend behavior. Furthermore, identifying seasonal trends can help manage or regulate water resources systems and irrigation and agricultural operations. In this study, the innovative trend significance test (ITST), the revised ITST, and the Wilcoxon signed-rank test, which are non-parametric methods, are proposed as alternative seasonal trend tests by combining them with the innovative polygon trend analysis (IPTA), which provides visual and linguistic examinations of seasonal behaviors. Groundwater level data from the Chilgrove House (United Kingdom), flow data from the Danube River Basin (Romania), precipitation and temperature data from Türkiye were used to compare the proposed methods with the seasonal Mann-Kendall (SMK) method. For temperature and groundwater level data, all methods showed an increasing trend at different confidence intervals, but for other data, trends emerged according to the characteristics of the methods. So, some of the proposed methods are more rigid than the SMK in trend detection, while others are more sensitive. In addition to the advantage of its applications to seasonal trend behaviors, the proposed significance tests are combined with the IPTA method and comparable alternative methods to the SMK. So, seasons with a clear increase or decrease can be seen visually in the proposed combined methods contrary to the SMK method. Thus, both seasonal trend behaviors and inter-seasonal transitions can be examined graphically, and seasonal significance testing can be applied. According to the characteristics of these combined methods, they can be used not only for seasonal trend tests, just like the SMK method, but also for regional trend tests using stations data instead of seasons.
AtıfScopus28WoS25OpenAlex30İncele
- MakaleAçık Erişim2025Scopus SJRQ4DYE REMOVAL PERFORMANCE AND BIOLOGICAL ACTIVITIES OF IRON OXIDE NANOPARTICLES SYNTHESIZED FROM Cotoneaster sp. FRUIT EXTRACT
Akar, Bülent; Baltacı, Cemalettin; Düzgün, Azer Özad; Karpuz, Omer; Karakullukçu, Volkan; Erdoğdu, Esma Gülbahar
This work aimed to study the antioxidant, antibacterial, and dye adsorption capabilities of the aqueous extract of Cotoneaster sp. fruits (CFE) and iron oxide nanoparticles (CF-FeONP) green-synthesized from the CFE. CF-FeONPs were characterized using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) analyses. The antioxidant activity of CFE and CF-FeONPs was assessed through various tests, including ABTS radical scavenging activity, DPPH radical scavenging activity, iron-reducing antioxidant power (FRAP), total phenolic content (TPC), total flavonoid content (TFC), and total antioxidant content (TAC). The CF-FeONPs had superior antibacterial and antioxidant activity compared to the CFEs. Furthermore, CF-FeONPs suppressed the growth of Gram-negative bacteria such as Yersinia pseudotuberculosis ATCC 911, Escherichia coli ATCC 25922, Proteus vulgaris ATCC 13315, and Pseudomonas aeruginosa ATCC 43288, as well as by Gram-positive bacteria like Streptococcus pyogenes ATCC 19615, Staphylococcus aureus ATCC 25923. and Bacillus subtilis ATCC 6633. The microdilution medium technique was used to determine the minimum inhibitory concentration (MIC) of CFE and CF-FeONPs against these bacteria strains. The adsorption rates of CF-FeONPs exhibited variability based on the quantity of adsorbent used and the specific dye type, whereas the lowest adsorption rate was 250 mg/L. CF-FeONPs demonstrated higher adsorption capacities for malachite green (MG) dye compared to methylene blue (MB) and phenol red (PR).
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- MakaleYayıncıda açık erişim2025Scopus SJRQ1Inheritance in the Mandailing Community: Value Changes from a Legal Culture Perspective
Hsb, Putra Halomoan; Siregar, Fatahuddin Aziz; Karimullah, Suud Sarim
This study explores the concept of marbagi dos in relation to the changing inheritance practices of the Mandailing community, viewed through the lens of legal culture. Marbagi dos, which literally means equal in the Mandailing indigenous people, has traditionally had a very important social dimension and equality. The type of research methodology used in this study is qualitative with a descriptive approach. The research data was obtained through interview techniques and participatory observation. In-depth interviews will be carried out with traditional leaders, scholars, and community members who play a direct role in the inheritance process. Using a legal culture approach, this study analyzes how the changes in values in Mandailing society are influenced by Islam which has implications for changes in inheritance practices in Mandailing, as well as how the community balances customary traditions with modern equality demands. The results of the study show that this inheritance transformation is a reflection of the adaptation of the Mandailing people to social changes, while maintaining cultural values within the framework of customary law. The implications of this study suggest that customary law is dynamic and capable of adapting to Islamic law and state law, highlighting the need for synergy between these three legal systems in crafting more inclusive policies.
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- MakaleAçık Erişim2025Scopus SJRQ1Investigation of perceived parental attitude in children exposed to sexual abuse: A case-control study
Bayrak, Nurten Gülsüm; Emirza, Elif Güzide; Uzun, Sevda
Background: The enduring impact of children being subjected to sexual abuse is characterized by lasting traumatic effects. Aims: This study aims to assess the influence of perceived parental attitudes on the incidence of sexual abuse in children who have experienced such abuse, comparing them with a control group. Methods: The research took place at the Child Advocacy Center (CAC) of a hospital in northern Turkey and in the pediatric outpatient clinics of the same institution. The study evaluated 101 children who were exposed to sexual abuse and 100 children who were not. Data collection took place between November 2022 and August 2023. The study employed a ‘Descriptive Information Form’ and the ‘Parental Attitude Scale’ for both case and control groups. The t-test for independent samples, descriptive statistics, and logistic regression analysis were used for data analysis. Results: Analysis of scores from the Parental Attitude Scale revealed significantly lower mean scores in acceptance-involvement and strictness-supervision in the case group (p <.05). The mean scores for ‘acceptance-involvement’ (X¯ = 22.82 ± 6.26, X¯ = 25.71 ± 3.89) were highest in the case and control groups. Neglectful attitude (38.6%) was more prevalent in the case group, while the control group exhibited a higher frequency of democratic attitude (37%). In terms of predictors, acceptance-involvement (OR = 1.091, p =.005) and maternal employment (OR = 4.410, p <.001) were identified as the most significant predictors of exposed to sexual abuse. The study’s Cronbach’s alpha value for the scale was α =.743. Conclusion: The study’s findings on parental attitudes suggest a potential connection between children’s exposure to sexual abuse and inadequate parental acceptance, involvement, supervision, and control.
- MakaleAçık Erişim2025Scopus SJRQ1An Examination of Relationships Between Postural Habits and Awareness of Fatigue and Musculoskeletal Discomfort in Nurses
Tuncer, Metin; Tuncer, Gülsüm Zekiye; Turan, Şeyma; Khorshtd, Leyla
Introduction: Prolonged fatigue, caused by the hospital's demanding workload and physical demands, can increase strain on the musculoskeletal system, leading to musculoskeletal issues that may negatively impact nurses' job performance and quality of life. High postural awareness, on the other hand, can help nurses develop correct posture and movement habits, reducing the risk of experiencing discomfort, thus preserving their physical health and supporting workforce sustainability. Therefore, it is of particular importance to determine the relationship of postural awareness to fatigue and musculoskeletal discomfort in nurses working in a hospital environment with heavy working conditions and many ergonomic risks. Aim: The aim of this study was to describe the postural habits, awareness, occupational fatigue levels and musculoskeletal disorders of nurses working in hospitals and to examine the relationships between these factors. Method: This study used a quantitative cross-sectional design. The study sample consisted of 132 nurses working in a hospital in Türkiye. The data for the study were collected between July and October 2023 using the Occupational Fatigue Exhaustion/Recovery Scale (OFER), Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) and Postural Habits and Awareness Scale (PHAS). Results: A significant positive, low-level correlation was found between the Recovery subscale of the OFER scale and the Postural Habits subscale of the PHAS scale (r = 0.277, p < 0.05). A significant negative, moderate-level correlation was observed between the Chronic Fatigue subscale of the OFER scale and the Postural Habits subscale of the PHAS scale (r = −0.311, p < 0.001). Additionally, a significant negative, moderate-level correlation was found between the Acute Fatigue subscale of the OFER scale and the Postural Habits subscale of the PHAS scale (r = −0.326, p < 0.001). Conclusion: This study found that as nurses' correct postural habits improved, both acute and chronic fatigue decreased, whereas recovery increased. It is suggested that interventions aimed at enhancing postural awareness and promoting correct postural habits in nurses may also positively influence occupational fatigue and exhaustion.
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- EditoryalYalnız künye2025Preface
Uğur, Ömer; Doğan, Kadir Caner
- MakaleYalnız künye2025Scopus SJRQ1Abusive supervision: can workplace friendships exacerbate work alienation and intent to quit?
Özbek, Mehmet Ferhat; Stefanidis, Abraham; Banai, Moshe; Akar, Vural
Purpose – Drawing on conservation of resources, similarity-attraction and social comparison theories, this research aims to examine how supervisors’ abusive behaviour influences employees’ intent to quit by investigating the mediating role of work alienation and the moderating role of workplace friendship. Design/methodology/approach – In Study I, time-lagged survey data were collected from 241 academic institutions’ employees at two separate times to empirically test the study’s hypotheses. In Study II, four different scenario manipulations were administered to 220 academic institutions’ undergraduate and graduate students. Both studies were conducted in Türkiye. Findings – The results of the survey indicate a positive relationship between employee exposure to supervisors’ abusive behaviour and their intent to quit, with work alienation mediating this relationship, and workplace friendship partially boosting the intensity of the negative effect. Similar results were confirmed by the findings of the survey conducted across four scenario manipulations in the education sector. Research limitations/implications – Despite the two-sector, two-instrument study design used, this research may only partially capture and explain the relationships among the studied variables. To enhance the generalisability of their findings, future studies should investigate broader cultural and occupational contexts, using both longitudinal and mixed-method designs. Practical implications – Strong workplace friendships may intensify the negative impact of abusive supervision, increasing staff alienation and turnover intentions, signalling risks for team stability and retention. Economic implications of high-level employee turnover should be considered by managers. Originality/value – This study challenges the prevailing assumption that workplace or academic friendships are universally beneficial. By demonstrating that strong workplace friendships can exacerbate the negative effects of supervisors’ or instructors’ abusive behaviour, it introduces a more nuanced understanding of interpersonal dynamics in organisational and educational settings.
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- MakaleYalnız künye2025Scopus SJRQ2“I Am Learning to Protect Myself with Mika”: An Evaluation of Self-Protection Behaviors of Turkish Preschoolers
Yılmaz Irmak, Türkan; Kızıltepe, Rukiye; Eslek, Duygu; Kütük, Bahtım; Güney, Onuray
Child sexual abuse (CSA) prevention programs contribute to increases in children’s knowledge and skills to protect themselves from CSA. However, there is a paucity of research investigating self-protection behaviors among children to demonstrate whether relevant CSA knowledge and skills are transferable in risky situations. We aimed to examine the effectiveness of the “I am learning to protect myself with Mika” program on preschool children’s self-protection behaviors. The sample included 51 preschool children (54.9% girls) from Izmir, Turkey and their parents. The mean age of the children was 65.57 months (SD = 7.21). The present study employed a posttest-only control group design, and the classrooms were randomly assigned to the intervention and wait-list comparison groups. The participating teachers implemented the program over a five-week period. Then, children’s self-protection behavior was assessed with children from both groups using a role-play scenario involving a request from a stranger. Accordingly, we tested whether children in the intervention group were more likely to demonstrate self-protection behaviors compared to those in the comparison group. The findings showed that the intervention group (77.3%) rejected the offer from strangers and behaved more safely than did the wait-list comparison group (24.2%; χ2(1) = 13.879, p < 0.001). “I am learning to protect myself with Mika” was found to be effective in contributing to preschoolers’ self-protective behaviors. The promising results obtained in this study may encourage further exploration of the behavioral outcomes of sexual abuse prevention programs.
- MakaleYalnız künye2025Scopus SJRQ2The Role of Service Innovation and Work Engagement on Creativity and Training-Learning Effort
Can, Ülker; Kiliçalp, Miray; Akyürek, Suat
Service innovation is a critical phenomenon for the service industry. The purpose of this study is to reveal whether service innovation directly affects employee creativity and their training-learning efforts, as well as whether work engagement has a mediating role in this relationship. In the context of the study, SEM was applied to analyze data collected from food and beverage employees of 5-star hotels. The results of the study revealed that service innovation and work engagement affected employee creativity and their training-learning efforts positively. This study makes a significant and original contribution to the hospitality literature because it is a new study model in terms of revealing the mediating effect of work engagement on employee creativity and their training and learning efforts. Furthermore, the implementation of this model by hotels can increase the success of food and beverage departments in ensuring employee work engagement which has a direct effect on the customer satisfaction process.
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- MakaleAçık Erişim2025Scopus SJRQ1Development and psychometric evaluation of the father-preterm infant bonding scale
Gül, Uğur; EFE, Emine; Bektaş, Murat
Objective: The purpose of this study is to describe the development process of the Father-Preterm Infant Bonding Scale (F-PIBS) and to report the results of its psychometric evaluation. Methods: A methodological, correlational, comparative, and cross-sectional design was employed. The study was conducted between June 2023 and September 2024 and included 182 fathers with preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU). Exploratory and confirmatory factor analyses were performed to evaluate the reliability of the scale, and validity was tested using Cronbach's alpha reliability coefficient, split-half reliability, item-total correlations, and Hotelling's T-squared test. Results: The scale comprises 10 items distributed across two sub-dimensions. The content validity ratios of the scale items ranged from 0.80 to 1.00. Cronbach's alpha values for the total scale and sub-dimensions were 0.878, 0.796, and 0.845, respectively. Conclusion: F-PIBS is reliable, valid, and appropriate for evaluating father-preterm newborn bonding levels in the NICU.
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- MakaleAçık Erişim2025Scopus SJRQ1Psychosocial problems experienced by intensive care nurses regarding sleep pattern within the scope of working conditions: A phenomenological study
Atasayar, Belgin Şen; Emirza, Elif Güzide; Uzun, Sevda
Background: Nurses working in intensive care units experience insomnia and accompanying psychosocial problems due to working conditions. Aim: This study explores with a phenomenological approach the psychosocial problems experienced by intensive care nurses regarding sleep patterns within the scope of working conditions. Study Design: In this phenomenological study, semi-structured in-depth interviews were conducted with 16 nurses working in the surgical intensive care unit of a state hospital in Türkiye. Criterion sampling method, one of the purposive sampling methods, was used to reach the sample group. Researchers' interviews continued until they reached data saturation. All interviews were recorded on a voice recorder after obtaining the necessary permissions from the nurses and then transcribed. The study data were evaluated using thematic analysis. The current manuscript was reported following the COREQ checklist. Results: Data analysis revealed three main themes (how working as an intensive care nurse changes sleep patterns, the relationship between shift work, work performance, patient care and how working as an intensive care nurse changes individual life and coping strategies) and nine subthemes (mental, physical, social, work performance, patient care, nutrition, family life, social life and coping). Conclusion: The study's findings revealed that nurses working in intensive care experienced psychosocial difficulties related to sleep patterns and had trouble coping. In particular, it was determined that sleep problems of intensive care nurses cause difficulties in family life, nutrition and social life. It is recommended that the number of personnel in workplaces be increased, overtime hours should be limited, and professional development and training on the importance of sleep for all nurses should be provided. Relevance to Clinical Practice: Nurses working in intensive care units may experience psychosocial problems due to working conditions, which may negatively change their coping skills. Therefore, organizing the working conditions of nurses positively changes their coping skills.
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- MakaleAçık Erişim2025Scopus SJRQ2Investigation of Nonstandard Finite Difference for Fractional Order Covid-19 Model
Merdan, Mehmet; Acikgoz, Pınar
This article examines a mathematical model of the Covid-19 type. We demonstrate how the population is impacted by immigration, protection, the mortality, exposure, curing, and interactions between sick and healthy individuals. There are five classifications in our model: exposed, susceptible, infected, quarantined, and recovered. The model is subjected to numerical and fractional analysis in this instance. The numerical analysis is performed using the fractional order non-standard finite difference (NSFD) scheme. The Grunwald-Letnikov numerical approximation technique is used for fractional analysis. The findings are evaluated by simulations using the Matlab tool.
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İncele - MakaleYalnız künye2025Scopus SJRQ3Factors Affecting Separation Anxiety Disorder in Adolescent Earthquake Survivors: The Case of Kahramanmaraş Earthquakes (2023)
Kiymis, Ibrahim; Dogan, Ahsen Aydin
Objective The Kahramanmaras Earthquakes (2023) are the largest and most devastating earthquakes in the history of the Republic. The effects of these earthquakes are particularly deeply felt among younger generations and trigger various psychological factors. Therefore, the aim of this study is to measure the levels of post-traumatic stress disorder (PTSD), social phobia (SP), generalized anxiety disorder (GAD), and depression on separation anxiety disorder (SAD) among adolescent earthquake survivors affected by the Kahramanmaras Earthquakes (2023). Methods In the study, the data were obtained using a survey method. A total of 605 adolescent earthquake survivors exposed to the Kahramanmaras earthquakes were reached. The research was analyzed using structural equation modeling (SEM). Results Surprisingly, according to the research findings, there was no significant and positive relationship between SP (β = -0.006, P > 0.05) and Depression (β = -0.117, P > 0.05) on SAD. Conclusions Consequently, while PTSD and GAD had significant and positive effects on SAD in those adolescent earthquake survivors affected by the Kahramanmaras Earthquakes (2023), SP and Depression did not have significant and positive effects on SAD. Therefore, it is recommended that future studies examine the effects of SP and Depression on SAD more comprehensively and in detail through qualitative research.
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- MakaleAçık Erişim2025Scopus SJRQ2The biological activity and phenolic content of endemic Astragalus baibutensis
Ozcan, Kadriye; Acet, Tuba; Yiğittürk, Gürkan
Astragalus baibutensis, is a plant endemic to Turkey, belonging to Fabaceae family, that is used as a folk medicine and food in this country. The purpose of this study is to find out the biological activities such as antioxidant, antimicrobial, enzyme inhibitory and DNA protective activity and also analyse the phenolic contents of the plant. To determine of antioxidant activity ABTS and DPPH assays were performed. Disc diffusion and microdilution methods were used to evaluate the antimicrobial activity. Additionally, enzyme inhibitory activities such as α-amylase, α-glucosidase, and tyrosinase were determined by using spectrophotometric methods. DNA protective activity was detected using pUC19 Plazmid DNA. The antiproliferative effect on SKOV-3 human ovarian cancer cells was examined by WST-8 assay. In addition, the phenolic contents were analysed by using HPLC. The biological activity of ethyl acetate extract of the root was found to be higher than those of other extracts. This extract had the highest amount of apigenin as phenolic compound. On the other hand, extracts showed moderate inhibition against the tested microorganism and antiproliferative properties in a concentration-dependent manner toward ovarian cancer cells. According to the results, Astragalus baibutensis has the potential for pharmaceutical and food additive usage.
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- MakaleAçık Erişim2025Scopus SJRQ2Changes of natural frequencies of masonry stone minarets due to temperature and humidity; [Yığma taş minarelerin doğal frekanslarının sıcaklık ve neme bağlı değişimleri]
Aymelek, Abdullah; Yanık, Yusuf; Yıldırım, Ömer; Türker, Temel
It is very important to distinguish the reason of change in natural frequencies of structures either caused by a possible damage or environmental conditions as temperature and humidity. In this study, the changes in the dynamic properties of masonry minarets under environmental effects such as temperature and humidity were investigated. The Minarets of İskenderpaşa, Hacı Kasım and Tavanlı Mosques in Trabzon were monitored by ambient vibration test method, the relationship between natural frequencies and temperature and humidity was tried to be determined. For this purpose, the natural frequencies of these minarets were measured at certain intervals under different temperature and humidity conditions over a period of approximately six months. The vibration measurement system which was developed by our research team was used in the measurements. From the data collected by these measurements, the variation intervals of the natural frequencies (the smallest and the highest values), the percentages of change and their relations with temperature and humidity were revealed. This relationship was determined by using linear-nonlinear simple and multiple regression analyses. From the study, it was found that the natural frequencies change under environmental effects such as temperature and humidity, and this rate of change was approximately 7%.
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İncele - MakaleYalnız künye2025Scopus SJRQ4Synthesis of New Triazole Compounds: Determination of Antiurease and Antioxidant Activities
Gümrükçüoğlu, T.İ.; Akgün, H.; Sökmen, B. Bilgin; Bektaş, H.
Abstract: Objective: In this study, we synthesized five novel triazole derivatives and biologically evaluated their antiurease and antioxidant properties. Methods: Five novel 1,2,4-triazole derivatives (5a–5e) were synthesized and tested for their urease inhibition and antioxidant activities using spectrophotometric methods. Results and Discussion: All compounds exhibited varying degrees of biological activity, with compound 5c demonstrating the most potent urease inhibition and radical scavenging capacity. Statistical analysis confirmed significant differences among the compounds, particularly highlighting the superior performance of 5c. Conclusions: These results suggest that halogen-substituted triazoles are promising candidates for further pharmacological development aimed at oxidative stress-related conditions and urease-associated pathologies.
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