Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Sezer, İsmet(6)
- Yıldız, Barış(6)
- Ayaydin, Hasan(5)
- Caliskan, A.(5)
- Erbaş, Sefa(5)
- Pala, Fahrettin(5)
- Sancak, Kadir(5)
- Yildiz, Emel(5)
- Çalışır, Gülsüm(5)
- Abada, A.(4)
- Abbrescia, M.(4)
- Abdyukhanov, I.(4)
- Abramov, A.(4)
- Aburaia, M.(4)
- Agrawal, P.(4)
- Aiba, M.(4)
- Aichinger, I.(4)
- Aielli, G.(4)
- Akay, A.(4)
- Akhundov, A.(4)
- Aksakal, H.(4)
- Albergo, S.(4)
- Alekou, A.(4)
- Aleksa, M.(4)
- Aleksan, R.(4)
- Alexahin, Y.(4)
- Alioli, S.(4)
- Aliyazicioglu, Yuksel(4)
- Altmannshofer, W.(4)
- Ambrosio, G.(4)
- Amorim, D.(4)
- Amstutz, O.(4)
- Anderlini, L.(4)
- Andreazza, A.(4)
- Andreini, M.(4)
- Andriatis, A.(4)
- Andris, C.(4)
- Andronic, A.(4)
- Angelucci, M.(4)
- Antinori, F.(4)
Yayınlar
- MakaleAçık Erişim2019Effect of pH on Protein Extraction from Mahaleb Kernels and Functional Properties of Resulting Protein Concentrate
Güzel, Melih; Çelik, Mehtap; Yildirim, Metin
The aims of this research were to examine the effect of pH on extraction of proteins from mahaleb (Prunus mahaleb L.) kernels, and to investigate the functional properties of resulting protein concentrate. The optimum pH values for the protein extraction and precipitation were determined as 10.0 and 4.5, respectively. The protein concentrate containing 92.73% dry matter, 6.29% ash, 6.02% carbohydrate, 1.42% fat and 73.11% protein was produced by using these extraction and precipitation pH values. Water-holding capacity, oil-holding capacity and the least gelling concentration of the protein concentrate were 2.81 g water/g, 1.66 g oil/g and 12%, respectively. Moreover, emulsifying activity and stability indices, foaming capacity and stability of protein concentrate were 27.21 m2/g, 81.05 min, 43.75% and 71.33% (after 30 min), respectively. The functional and chemical properties of the protein concentrate indicate that it may find application as functional ingredient for various food products.
- MakaleYalnız künye2019A new colorimetric method for CUPRAC assay with using of TLC plate
Akar, Zeynep; Burnaz, Nesibe Arslan
Cupric reducing antioxidant capacity (CUPRAC) method is one of the most widely used antioxidant methods. However, its need for a spectrophotometer, as in many other methods, is an important disadvantage. Cupric reducing antioxidant capacity was determined based on color analysis with Image J program in computer with the new method developed in this study and thus, use of spectrophotometer was eliminated. The new colorimetric CUPRAC assay was applied to various standard antioxidants and plant extracts. The reaction mixtures were dropped on TLC plate. The colors formed on TLC were transferred to the computer by using scanner images, and CTEAC value in μmol/L of each sample was determined with the image J program. The CTEAC values were compared with the TEAC values measured with the spectrometric method. A linear relationship was found between both (C)TEAC values of antioxidant standards (R2 = 0.991) and plant extracts (R2 = 0.994). Thus, the new method developed for the CUPRAC antioxidant assay can be easily performed in any environment without spectrophotometer device, and it is a low-cost method.
- Kitap BölümüYalnız künye2019COPRAS method with neutrosophic sets
Şahin, Rıdvan
Interval neutrosophic number (INN), which is descripted by the degree of truth-membership, indeterminacy-membership and falsity-membership of an element, is a powerful information tool with many application areas. The purpose of this study is to develop an extended form of COPRAS (Complex Proportional Assessment) method used for solving the decision making problems in which all the data presented by decision makers is in the form of interval neutrosophic matrix presented by INNs, and the information about criterion weights is partially known or completely unknown. In order to accomplish this goal, a new score function and an accuracy function that consider the decision maker’s risk attitude are defined under a parameter called the risk index to determine the ordering of INNs. Then, based on Maclaurin symmetric mean (MSM) operator that can capture the interrelationships among multi-input arguments, some aggregation operators are defined, such as interval neutrosophic Maclaurin symmetric mean (INMSM) operator and interval neutrosophic weighted Maclaurin symmetric mean (INWMSM) operator. Moreover, some optimization models are established to determine the subjective and objective weights of decision criteria. A numerical problem is solved to demonstrate the effective and feasible structure of the developed method. Then, a sensitive analysis is conducted according to the decision maker’s risk attitude, and the advantages of the developed method are listed. Finally, a comparison analysis is provided to present the relationships among the developed method and existing methods, and some conclusions are given at the end of the study.
- MakaleAçık Erişim2019Presence of different bacterial species in thermal sources and novelty in their industrial enzyme productions
Albayrak, Seyda; Genc, Berna; Ozkan, Hakan; Taskin, Mesut; Adiguzel, Ahmet
In this study, one hundred and thirty isolates were isolated from water and sludge samples taken from hot springs located in different regions of Turkey. Among them, eleven isolates were chosen according to conventional (morphological, physiological and biochemical tests) and molecular methods (rep-PCR and 16S rRNA sequencing). These bacteria were then tested for their capability to produce valuable enzymes. As a result; species belonging to Bacillus, Anoxybacillus, Aeribacillus, Enterococcus, Exiguobacterium and Paenibacillus were identified. Test strains were found to have optimum reproductive potential at pH 5.0-9.0 and 15-65°C, usually at a concentration of 1.0-10.0% (w/v) NaCl. In addition, all thermotolerant bacteria were Gram, endospore (except E. profundum), catalase and oxidase (except E. faecium and E. profundum) positive, and rod-shaped (except E. faecium). It was observed that all isolates had a 99% similarity percentage as a result of 16S rRNA sequence analysis. All of the isolates were capable of producing industrially important enzymes moreover, eight of them could produce at least two of these enzymes. Test strains had high potential of industrial enzyme production, and the enzymes from these thermo-tolerant isolates will be widely used in biotechnological processes.
- Derleme MakaleYalnız künye2019Automation in the Mining Industry: Review of Technology, Systems, Human Factors, and Political Risk
Rogers, W. Pratt; Kahraman, M. Mustafa; Drews, Frank A.; Powell, Kody; Haight, Joel M.; Wang, Yaxue; Baxla, Kritika; Sobalkar, Mohit
In the opinion of these authors, technology alone can never give an organization an edge over competitors or provide an industry step change. However, history has shown that technology applied with correct logistics and strategy makes a significant difference. Never has the minerals industry faced such daunting challenges and been in such need of a step change. Application of autonomous systems has been steadily increasing in the minerals industry. Automation technology has changed the mining value chain from exploration to mineral processing and refining. The future state will only see additional in-roads of automation into more processes and the whole system design. To better understand the near-future potential of automation, it is useful to explore and review the current state of automation in minerals development. A review of the state of automation research is given. The review will consider three critical areas: automation technology, system’s engineering and management processes around automation, and the role of human factors engineering in automated and semi-automated systems. The review ends with a discussion on the social and political risks of automation in terms of shared value and sustainable development.
- MakaleYalnız künye2019Exploring the value of using data: a case study of continuous improvement through data warehousing
Rogers, W. Pratt; Kahraman, M. Mustafa; Dessureault, Sean
The mining industry is adapting data-rich technology. Data management processes and infrastructure require additional investment which, can be difficult to justify. A valuation model for data management infrastructure would necessitate modelling the ‘use’ of data and quantifying the value and the likelihood of success of improvement initiatives. A model is presented which can assess the impacts of a data-driven initiative. The initiatives are shown to be the foundation of improved shift coordination resulting in significant and sustained operational improvements. This paper aims to illustrate the value of using data from source systems in mining operations.
- KitapYalnız künye2019Contemporary Debates on Politics and Public Administration in the Postmodern Era
Ugur, Ömer; Dogan, Kadir Caner
The volume provides a collection of articles on current debates in the fields of politics and public administration. The authors deal with frequently mentioned concepts of our era in political and public administration sciences.
- MakaleAçık Erişim2019FCC-ee: The Lepton Collider: Future Circular Collider Conceptual Design Report Volume 2
Abada, A.; Abbrescia, M.; AbdusSalam, S. S.; Abdyukhanov, I.; Fernandez, J. Abelleira; Abramov, A.; Aburaia, M.; Acar, A. O.; Adzic, P. R.; Agrawal, P.
In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today's technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics.
- MakaleAçık Erişim2019HE-LHC: The High-Energy Large Hadron Collider Future Circular Collider Conceptual Design Report Volume 4
Abada, A.; Abbrescia, M.; AbdusSalam, S. S.; Abdyukhanov, I.; Abelleira Fernandez, J.; Abramov, A.; Aburaia, M.; Acar, A. O.; Adzic, P. R.; Agrawal, P.
In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries.
- MakaleAçık Erişim2019Prostate volume effect on Gleason score upgrading in active surveillance appropriate patients
Çamur, Emre; Coskun, Alper; Kavukoglu, Ovunc; Can, Utku; Kara, Onder; Çamur, Arzu Develi; Sarica, Kemal; Narter, Kamil Fehmi
Introduction: Gleason Score (GS) upgrading rates in the literature are reported to be around 33-45%. The relationship between prostate volume and GS upgrading should be defined, aiming to reduce upgrading rates in patients with low risk groups who are eligible for active surveillance (AS) or minimally invasive treatment, by varying biopsy cores, or lengths of cores according to prostate volumes. In this regard, the aim of our study was to establish the relationship between prostate volume and GS upgrading. Materials and methods: We retrospectively analyzed the medical records of 78 patients, who were appropriate for AS between 2011-2016 at our hospital. Inclusion criteria were patient age under 65 years, PSA level under 10 ng/ml, GS (3 + 3) or (3 + 4), and 3 or less positive cores, clinical stages <= T2. GS increase in radical prostatectomy specimen was considered as 'upgrading' and in addition, score reported by biopsy as 3 + 4 but in surgical specimen as 4 + 3 were also considered as 'upgrading'. The effect of prostate volume on Gleason grade upgrading was examined by calculating upgrading rates separately for patients with prostate volume 30 ml or less, those with 30 to 60 ml, and those over 60 ml. Results: As a result of the analysis of the data, upgrading was seen in 35 (44.8%) of 78 patients included in the study. In the cohort mean prostate volume was 49.8 (+/- 26.3) ml. Twenty-two patients (28.2%) had prostate volume 30 ml or less, 34 (43.6%) 30 to 60 ml, and 22 (28.2%) 60 ml or more. The patients were divided into two groups as those with and without GS upgrading. Between the groups prostate volume and prostate volume range (0-30/31-60/> 60) were not significantly different (p value > 0.05). Conclusions: Gleason grade upgrading causes patients to be classified in a lower risk group than they actually are, and may lead to inappropriate treatment. This condition has a direct effect on the decision of active surveillance. Therefore, it is important to define the factors that can predict GS upgrading in active surveillance appropriate patients. In this study, we found that prostate volume has no significant effect on upgrading in active surveillance appropriate patients.
- MakaleAçık Erişim2019Anticholinergic, antidiabetic and antioxidant activities of cinnamon (cinnamomum verum) bark extracts: polyphenol contents analysis by LC-MS/MS
Gulcin, Ilhami; Kaya, Ruya; Goren, Ahmet C.; Akincioglu, Hulya; Topal, Meryem; Bingol, Zeynebe; Cakmak, Kader Cetin; Sarikaya, Sevim B. Ozturk; Durmaz, Lokman; Alwasel, Saleh
Ethanolic (EEC) and aqueous (WEC) extracts of cinnamon (Cinnamomum verum) were evaluated for their antioxidant profiles by eight distinguished bioanalytical antioxidant methods. Their inhibitory effects were tested against some enzymes including acetylcholinesterase, butyrylcholinesterase, alpha-glycosidase and alpha-amylase, which linked to different diseases. Additionally, the antioxidant properties were determined and polyphenolic compositions of the both extracts were evaluated by LC-MS/MS analysis. According to the LC-MS/MS experiments, thirteen compounds were found in WEC and EEC. Also, p-hydroxybenzoic acid (321.1 mg/kg extract), p-coumaric acid (291.4 mg/kg extract), and pyrogallol (142.4 mg/kg extract) were found to be the most abundant ingredients in the WEC. On the other hand, pyrogallol (264.3 mg/kg extract), ferulic acid (224.7 mg/kg extract) and p-coumaric acid (170.2 mg/kg extract) were found as the most plentiful chemicals in the EEC. For the estimation of the antioxidant capacities of the both extracts (WEC and EEC), DPPH center dot and ABTS(center dot+) scavenging activities, as well as Fe3+-Fe2+, and Cu2+-Cu+ reducing assays were studied. The IC50 values of the WEC and EEC indicated that they were potent effective DPPH center dot (21. 25 and 15.71 mu g/mL) and ABTS(center dot+) (6.52 and 5.79 mu g/mL) scavengers, as well as AChE (221.33 and 110.26 mu g/mL), BChE (461.69 and 94.93 mu g/mL), alpha-glycosidase (206.86 and 220.00 mu g/mL) and alpha-amylase (189.86 and 200.86 mu g/mL) inhibitors. As a conclusion, both EEC and WEC had rich phenolic contents and demonstrated effective anticholinergic, antidiabetic and antioxidant effects.
- MakaleYalnız künye2019A novel niosome formulation for encapsulation of anthocyanins and modelling intestinal transport
Fidan-Yardimci, Melike; Akay, Seref; Sharifi, Fatemeh; Sevimli-Gur, Canan; Ongen, Gaye; Yesil-Celiktas, Ozlem
The bioavailability of drugs can be improved by regulating the structural properties, particularly lipoid systems, such as niosomes, can increase cellular uptake. Herein, we optimized double emulsion and niosomal formulations for encapsulating anthocyanin-rich black carrot extract. Nanoparticles obtained by selected formulation were characterized in terms of morphology, particle size, drug encapsulation efficiency, in vitro release and cytotoxicity. The optimum conditions for niosomal formulation were elicited as 30 mg of cholesterol, 150 mg of Tween 20 and feeding time of 1 min at a stirring rate of 900 rpm yielding the lowest average particle size of 130 nm. In vitro release data showed the majority of the encapsulated anthocyanins were released at the end of 10 h. A mathematical model was developed to estimate the absorption of anthocyanins released from niosomes and cytotoxicity was assessed against neuroblastoma. Overall, these findings suggest that niosomal vesicles might be suitable delivery systems for anthocyanins.