Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2022Scopus SJRQ1
    COVID-DSNet: A novel deep convolutional neural network for detection of coronavirus (SARS-CoV-2) cases from CT and Chest X-Ray images

    Reis, Hatice Catal; Turk, Veysel

    COVID-19 (SARS-CoV-2), which causes acute respiratory syndrome, is a contagious and deadly disease that has devastating effects on society and human life. COVID-19 can cause serious complications, especially in patients with pre-existing chronic health problems such as diabetes, hypertension, lung cancer, weakened immune systems, and the elderly. The most critical step in the fight against COVID-19 is the rapid diagnosis of infected patients. Computed Tomography (CT), chest X-ray (CXR), and RT-PCR diagnostic kits are frequently used to diagnose the disease. However, due to difficulties such as the inadequacy of RT-PCR test kits and false negative (FN) results in the early stages of the disease, the time-consuming examination of medical images obtained from CT and CXR imaging techniques by specialists/doctors, and the increasing workload on specialists, it is challenging to detect COVID-19. Therefore, researchers have suggested searching for new methods in COVID- 19 detection. In analysis studies with CT and CXR radiography images, it was determined that COVID-19-infected patients experienced abnormalities related to COVID-19. The anomalies observed here are the primary motivation for artificial intelligence researchers to develop COVID-19 detection applications with deep convolutional neural networks. Here, convolutional neural network-based deep learning algorithms from artificial intelligence technologies with high discrimination capabilities can be considered as an alternative approach in the disease detection process. This study proposes a deep convolutional neural network, COVID-DSNet, to diagnose typical pneumonia (bacterial, viral) and COVID-19 diseases from CT, CXR, hybrid CT + CXR images. In the multi-classification study with the CT dataset, 97.60 % accuracy and 97.60 % sensitivity values were obtained from the COVID-DSNet model, and 100 %, 96.30 %, and 96.58 % sensitivity values were obtained in the detection of typical, common pneumonia and COVID-19, respectively. The proposed model is an economical, practical deep learning network that data scientists can benefit from and develop. Although it is not a definitive solution in disease diagnosis, it may help experts as it produces successful results in detecting pneumonia and COVID-19.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus36WoS22OpenAlex36
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2022
    Automatic prediction of covid-19 from chest-computed tomography (CT) images using deep learning architectures; [Derin öğrenme mimarilerini kullanarak göğüs BT görüntülerinden otomatik Covid-19 tahmini]

    Turk, Veysel; Catal Reis, Hatice; Kaya, Serhat

    Machine learning has been actively used in disease detection and segmentation in recent years. For the last few years, the world has been coping with the Coronavirus disease 2019 (COVID-19) pandemic. Chest-computerized tomography (CT) is often a meaningful way to detect and detect patients with possible COVID-19. This study aims to classify COVID-19 and non-COVID-19 chest-CT images using deep learning (DL) algorithms and investigate whether we can achieve successful results in different parameters using four architectures. The study was performed on proved positive COVID-19 CT images, and the datasets were obtained from the GitHub public platform. The study evaluated four different deep learning architectures of VGG16, VGG19, LeNet-5, and MobileNet. The performance evaluations were used with ROC curve, recall, accuracy, F1-score, precision, and Root Mean Square Error (RMSE). MobileNet model showed the best result ; F1 score of 95%, the accuracy of 95%, the precision of 100%, recall of 90%, AUC of 95%, and RMSE of 0.23. On the other hand, VGG 19 model gave the lowest performance; F1 score of 90%, the accuracy of 89%, the precision of 90%, recall of 90%, AUC of 89%, and RMSE of 0.32. When the algorithms' performances were compared, the highest accuracy was obtained from MobileNet, LeNet-5, VGG16, and VGG19, respectively. This study has proven the usefulness of deep learning models to detect COVID-19 in chest-CT images based on the proposed model framework. Therefore, it can contribute to the literature in Medical and Engineering in COVID-19 detection research.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus2OpenAlex2
    ScopusTR Dizinİncele
  • MakaleYalnız künye2022Scopus SJRQ2
    Effect of different objective functions on control performance of tuned mass damper for a high-rise building considering soil–structure interaction

    Araz, Onur; Ozturk, Kasif Furkan; Cakir, Tufan

    This paper deals with the optimization of the tuned mass damper (TMD) with different objective functions for high-rise building under earthquake motions considering soil–structure interaction (SSI). A study is conducted to search for the TMD that outperforms five objective functions (i.e., OF-1–OF-5) containing combinations of the structural responses and foundation responses. The main goal of the present study is to evaluate and compare the control performance of these five objective functions. The optimum parameters of TMD are obtained by particle swarm algorithm (PSA) to minimize the acceleration transfer function. To determine the dynamic response of a 40-story building under the influence of SSI, six different foundation soil conditions and eight different earthquake records are considered. The results show that the SSI effects on the dynamic response of the high-rise building resting on relatively soft soil types such as SD and SE are of critical importance. It is shown that the effectiveness of the optimum TMD designed by OF-1 is better than the others in suppressing the peak response values for all soil types. After OF-1, the best performances are obtained for OF-3 and OF-5 which yield approximately the same effectiveness. It is also found that different earthquake records, soil types and objective functions are very effective on the effectiveness of TMD.

    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
    AtıfScopus22WoS22OpenAlex25
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2022Scopus SJRQ2
    40Ar–39 Ar dating, whole-rock and Sr-Nd isotope geochemistry of the Middle Eocene calc-alkaline volcanic rocks in the Bayburt area, Eastern Pontides (NE Turkey): Implications for magma evolution in an extension-related setting

    Kaygusuz, Abdullah; Yücel, Cem; Aydınçakır, Emre; Gücer, Mehmet Ali; Ruffet, Gilles

    Discussions continue about whether Middle Eocene magmatism in the Eastern Pontides is associated with collision or subduction. This paper presents new whole-rock geochemistry, Sr-Nd isotopic and 40Ar-39Ar age data for Middle Eocene volcanic rocks from the Bayburt area of the Eastern Pontides (NE Turkey) to investigate their sources and evolutionary history. The new 40Ar–39Ar ages reveal that these volcanic rocks erupted between 44.6 ± 0.1 Ma and 43.5 ± 0.1 Ma, within the Lutetian (Middle Eocene). The studied volcanic rocks are composed of basalt, andesite, basaltic andesite and minor dacite lava and pyroclastic rocks. These rocks consist of plagioclase, amphibole, pyroxene, olivine, biotite, sanidine and minor quartz phenocrysts with Fe-Ti oxides. They have microlithic, hyalo-microlithic, porphyritic and rarely glomeroporphyritic textures. The volcanic rocks have low to high-K calc-alkaline affinities. They display enrichment in large-ion lithophile elements and depletion in high-field strength elements with high Th/Yb ratios, which indicate that the magmas forming the volcanic rocks were derived from lithospheric mantle sources enriched by mostly slab-derived fluids in the spinel stability field. 87Sr/86Sr(i) values vary between 0.70485 and 0.70551 and 143Nd/144Nd(i) values vary between 0.51255 and 0.51267. These data correspond to the mantle array on the isotope ratio diagram. The main solidification processes consist of fractional crystallization with minor assimilation. In light of the data obtained in this study together with data from previous studies, petrogenetic character of the Middle Eocene magmas from the southern parts of the Eastern Pontides may be explained by melting of an enriched lithospheric mantle source initially metasomatized by subduction fluids in a post-collisional extensional-related tectonic setting.

    AtıfScopus17WoS14OpenAlex20
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2022Scopus SJRQ1
    A countrywide analysis of 27 solar power plants installed at different climates

    Ozden, Talat

    The world is still heavily using nonconventional energy sources, which are worryingly based on carbon. The step is now alternative energy sources hoping that they will be more environmentally friendly. One of the important energy conversion forms by using these sources is photovoltaic solar systems. These type of power plants is on the increase in everyday on the world. Before investment a solar power plant in a specified region, a techno-economic analyse is performed for that power plant by using several meteorological data like solar irradiance and ambient temperature. However, this analyses generally lacks evaluation on effects of climatic and geographical conditions. In this work, 5 years of data of 27 grid-connected photovoltaic power plants are investigated, which are installed on seven different climate types in Turkey. Firstly, the power plants are categorized considering the tilt angles and Köppen–Gieger climate classification. The performance evaluations of the plants are mainly conducted using monthly average efficiencies and specific yields. The monthly average efficiencies, which were classified using the tilts and climate types were from 12 to 17%, from 12 to 16% and from 13 to 15% for tilts 30°/10°, 25° and 20°, respectively. The variation in the specific yields decrease with elevation as y(x) = − 0.068x + 1707.29 (kWh/kWp). As the performances of photovoltaic systems for some locations within the Csb climatic regions may relatively lower than some other regions with same climate type. Thus, techno-economic performance for PVPP located in this climate classification should be carefully treated.

    • SDG 7 · Erişilebilir ve Temiz Enerji
    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    • SDG 13 · İklim Eylemi
    AtıfScopus6WoS2OpenAlex8
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2022Scopus SJRQ1
    Seismic performance of a high-rise building by using linear and nonlinear methods

    Çavdar, Özlem

    In this paper, the seismic behavior of the existing reinforced concrete tall building is investigated by using the linear and nonlinear dynamic methods. The selected existing reinforced concrete structure was designed according to Turkey Seismic Code-2007. The performance analysis according to the Turkey Building Earthquake Code-2019 is realized in a 41-story reinforced concrete shear wall-framed structure in Istanbul where active fault lines are located. For high-rise building, firstly, spectrum analysis according to mode superposition methods of linear computational methods used within the scope of strength-based design is performed. Turkey Building Earthquake Code-2019 advises a nonlinear deformation-based design approach to determine more accurately the behavior of high-rise building, as in the earthquake regulations of other developed countries. In addition, the nonlinear time history analyses of building were performed. At the end of the study, torsional irregularity is seen on the normal floors and intermediate floor; stiffness irregularity was found on second floors. In addition, it has been observed in some of the oblique columns of the building that load bearing capacities were exceeded due to creep, axial compressive loads and severe damages occurred. According to the Turkey Building Earthquake Code-2019, the high-rise reinforced concrete shear wall building is not expected to satisfy life safety performance levels under design earthquake.

    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
    AtıfScopus5WoS3OpenAlex6
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2022Scopus SJRQ2
    A note on linear non-Newtonian Volterra integral equations

    Güngör, Nihan

    In this study, the Volterra integral equations are defined in the non-Newtonian calculus with the aid of ∗ -integral. The focus of this study is obtaining the solution of linear non-Newtonian integral equations. The ∗ -resolvent kernel method, successive approximations method and Adomian decomposition method are applied for solving non-Newtonian integral equations in the non-Newtonian sense. Some numerical examples are presented to explain the procedure of these methods. Finally, a model that describes a type of the exponential growth model is proposed in the sense of non-Newtonian calculus as an example.

    AtıfScopus8WoS8OpenAlex7
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2022Scopus SJRQ1
    Early Cambrian S-type granites in the Sakarya Zone, NE Turkey: A record for transition from subduction to post-collisional extension deduced from U-Pb zircon age and Nd-Hf isotopes

    Karsli, Orhan; Sengün, Firat; Dokuz, Abdurrahman; Aydin, Faruk; Kandemir, Raif; Kristoffersen, Magnus; Santos, Jose Francisco; Hofmann, Mandy; Duygu, Levent

    Cadomian realms have recently received much attention in the Alpine-Mediterranean orogenic belts, with discontinuous outcrops extending from the Alps to the Istanbul Zone, Menderes Massif, Taurides in Turkey and Iran as well. However, they have not been identified in the Sakarya Zone, northern Turkey to date. Here, we present, for the first time, zircon U-Pb geochronology, zircon Hf-isotopes and trace elements as well as whole-rock geochemistry and Nd-isotopes from the Karamese metagranitoid in the Yusufeli (Artvin) area, NE Turkey. The zircon U-Pb age data demonstrate that the Karamese metagranitoid intruded into the Precambrian basement units in the Early Cambrian (ca. 534-530 Ma). Zircon overgrowths in the Karamese metagranitoid interpreted as a result of metamorphic overprint yielded ages of 328 Ma. This age indicates that the Sakarya Zone experienced the Variscan metamorphic events at 328 Ma. The Early Cambrian metagranitoid shows that some rocks in the basement of the Sakarya Zone date back to Precambrian in age. The Karamese metagranitoid is an S-type granite, with high modal content of muscovite (similar to 10%). The samples show highly peraluminous [A/CNK = molar Al2O3/(CaO + K2O + Na2O) = 1.34-1.58] and medium-K calc-alkaline geochemical affinities. The Karamese metagranitoid displays low REE concentrations and a slight positive Eu anomaly and show slightly light REEs and LILEs enrichments, and HFSEs depletions. The samples have negative epsilon(Nd)(t) of -4.76 to -2.90 and epsilon(Hf) (t) of -4.75 to -1.08 values. These geochemical-isotopic characteristics reveal that the Karamase metagranitoid originated through fluid-absent muscovite dehydration melting of heterogeneous metasedimentary source rocks (mostly greywacke), with a minor input of juvenile mafic melt. We argue that the Early Paleozoic metagranitoids along the eastern Sakarya Zone is an expression of crustal thinning in the Cadomian orogenic belt in northern Gondwana, with the tectonic turnover from convergent margin to crustal extension possibly induced by break-off of Tornquist oceanic lithosphere which is a branch of Iapetus Ocean during Early Cambrian.

    AtıfScopus16WoS14OpenAlex15
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2022Scopus SJRQ2
    Warm up with music and visual feedback can effect Wingate performance in futsal players

    Bayrakdaroglu, Serdar; Eken, Oezgur; Yagin, Fatma Hilal; Bayer, Ramazan; Gulu, Mehmet; Akyildiz, Zeki; Nobari, Hadi

    Purpose: Visual feedback and music while warm up may help elicit peak performance, but its effect during the Wingate anaerobic test (WAnT) in futsal players is unexplored. Therefore, the aim of this study was to examine the effects of music and visual stimulus on WAnT performance in futsal players. Methods: The study included 17 young male futsal players (age, 21.53 +/- 1.32 years; height, 177.59 +/- 5.75 cm; 73.71 +/- 9.31 kg; BMI 23.342 +/- .47). The WAnT was administered using three distinct protocols: with music (M), without music (NM), and with music and visual feedback (MV) following a 10-min warm-up at 72-h intervals. After WAnT, the following parameters were evaluated: (a) peak power output: PPO (W), (b) relative peak power output: RPPO (W/kg), (c) mean power output: MPO (W), (d) relative mean power output: RMPO (W/kg), (e) fatigue index: FI (%), and (f) minimum power output MIPO (W). Results: MV indicated that futsal players' WAnT values, including PPO, RPPO, MPO, RMPO, and MIPO improved more than with other protocols (p < 0.05). However, there was no significant difference between protocols for FI (%) WAnT values (p > 0.05). Conclusions: Listening to music and watching visual feedback while warm up before performing WAnT performance suggest to coaches and futsal players.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus6WoS5OpenAlex12
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2022Scopus SJRQ2
    Diurnal variation in Uchikomi fitness test performance: Influence of warm-up protocols

    Eken, Oezguer; Yagin, Fatma Hilal; Eken, Ismihan; Gabrys, Tomasz; Knappova, Vera; Bayrakdaroglu, Serdar; Akyildiz, Zeki; Nobari, Hadi

    Performance is judged using a variety of methods to ensure uniformity between competitions. Uchikomi Fitness Test (UFT) could accomplished between morning qualifying and evening finals. The purpose of this study is to investigate the impact of different warm-up protocols on UFT at different times of the day in female judokas. Ten volunteer women who had been practising judo on a regular basis for more than 5 years and actively competed in international tournaments took part in this study. Judokas completed UFT, either after no-warm-up (NWU), specific warm-up (SWU), and linear+lateral warm-up (FWU) protocols for two times a day in the morning: 09:00-11:00 and in the evening: 16:00-18:00, on non-consecutive days. In conclusion, there was a significant increase in UFT scores (F = 9.89; p = 0.002), a + b (F = 4.42; p = 0.04) and heart rate (F = 28.99; p < 0.001) in the early evening compared to the morning. Increases in UFT performance were observed in the SWU protocol compared to the NWU and FWU protocols (p < 0.05). However, the interaction between time of day and warm protocol was not significant (p > 0.05). The UFT performance revealed diurnal variation, and the judokas' performances may be favourably affected more in the late hours, particularly following SWU procedures.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus9WoS7OpenAlex8
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2022Scopus SJRQ1
    The concept of pain inventory for children: The reliability and validity study of the Turkish version

    Cirik, Vildan Apaydin; Bulut, Elif; Aksoy, Bahar; Coemert, Hatice Sonay Yalcin; Pate, Joshua W.

    Background and purpose: Pain experiences in childhood are very likely to be reflected in adulthood. The early evaluation of the concept of pain in children may eventually lead to.better patient outcomes in the future. Therefore, we aimed to culturally and developmentally adapt the Concept of Pain Inventory for Children (COPI) for Turkish children.Methods: This descriptive, correlational study was conducted with 239 post-operative children aged 8-12 years between June and December 2021. The research adhered to COSMIN guidelines. The data were collected using a descriptive information form and the COPI. Factor analysis, Cronbach's alpha, and item-total score analysis were used for the data analysis.Results: The resulting unidimensional scale consists of 12 items in Turkish. The scale explained 65% of the total variance. The exploratory factor analysis showed that the factor loadings of items ranged from 0.64 to 0.91. The confirmatory factor analysis showed that the factor loadings of items ranged from 0.66 to 0.92. Goodness of fit indexes were found to be as follows: Normed Fit Index >0.90; Incremental Fit Index >0.90; Comparative Fit Index >0.90; and the Root Mean Square Error of Approximation <0.08. The total Cronbach's alpha coefficient of the scale was 0.78 (reliable). Conclusions: The 12-item Turkish translation of the COPI was deemed valid and reliable in 8-12-year-old children in a post-operative setting. Practice implications: Evaluation of children's pain concepts during childhood may contribute to the identification of conceptual gaps for pain science education.(c) 2022 Elsevier Inc. All rights reserved.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus4WoS4OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2022Scopus SJRQ2
    The first record of Scapania cuspiduligera (Marchantiophyta: Scapaniaceae) in Turkish and Southwest Asia liverwort flora supported from molecular data

    Batan, Nevzat; Vilnet, Anna; Abay, Gokhan; Erata, Huseyin; Özdemir, Turan

    During the recent bryological excursion to the Rize region of Turkey, Scapania cuspiduligera has been collected, it is the first record of this species to Turkey and Southwest Asia. Brief description, illustration, ecological, ITS1-2 nrDNA and trnL-F cpDNA sequence data are provided and discussed.

    AtıfScopus3WoS3OpenAlex5
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2021Scopus SJRQ1
    Investigation of wear behavior of graphite additive composite coatings deposited by micro arc oxidation-hydrothermal treatment on AZ91 Mg alloy

    Küçükosman, Rıdvan; Emine Şüküroğlu, Ebru; Totik, Yaşar; Şüküroğlu, Süleyman

    Composite coatings were deposited on AZ91 magnesium alloys by micro arc oxidation (MAO) and the MAO-hydrothermal treatment (HT). The MAO process of Mg alloys was performed in the silicate/phosphate-based electrolyte with graphite particles size of 5-10 and 75 µm and then the obtained samples were submitted to hydrothermal treatment at 150°C in the graphite-ethanol mixture. The structural and morphological properties of composite coatings were analized X-ray diffraction (XRD) and scanning electron microscopy (SEM). The wear resistance was examined with ball-on-disc tribometer. The addition of graphite to the MAO electrolyte solution increased the coating thicknesses and compactness and the surface morphologies acquired relatively a homogeneous appearance. The coating surfaces were enriched in graphite by HT and the wear test results showed that the wear resistance of the graphite-doped MAO-HT composite coatings was significantly improved.

    AtıfScopus45WoS41OpenAlex38
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2021Scopus SJRQ2
    Innovative and polygonal trend analyses applications for rainfall data in Vietnam

    Şan, Murat; Akçay, Fatma; Linh, Nguyen Thi Thuy; Kankal, Murat; Pham, Quoc Bao

    It is a known fact that the size, frequency, and spatial variability of hydrometeorological variables will irregularly increase under the impact of climate change. Among the hydrometeorological variables, rainfall is one of the most important. Trend analysis is one of the most effective methods of observing the effects of climate change on rainfall. Recently, new graphical methods have been proposed as an alternative to classical trend analysis methods. Innovative Polygon Trend Analysis (IPTA), which evolved from Innovative Trend Analysis (ITA), is currently one of the proposed methods and it does not contain any assumptions. The aim of this study is to compare IPTA, ITA with the Significance Test and Mann-Kendall (MK) methods. To achieve this, the monthly total rainfall trends of 15 stations in the Vu Gia-Thu Bon River Basin (VGTBRB) of Vietnam have been examined for the period 1979–2016. The analyses show that rainfall tends to increase (decrease) in March (June) at nearly all stations. IPTA and ITA with the Significance Test are more sensitive than MK in determining the trends. While trends were detected in approximately 90% of all months in IPTA and ITA with the Significance Test, this rate was only 23% in the MK test. Although the arithmetic mean graphs in the 1-year hydrometeorological cycle are considerably regular at almost all stations, their standard deviations are relatively irregular. The most critical month for trend transitions between consecutive months for all the stations is October, which has an average trend slope of −1.35 and a trend slope ranging from −3.98 to −0.21, which shows a decreasing trend.

    • SDG 13 · İklim Eylemi
    AtıfScopus81WoS71OpenAlex87
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2021
    Relationship between Political and Financial Risks in Turkey: Evidence from Fourier Cointegration Analysis Regarding Institutional Structures; [Türkiye’de Politik ve Finansal Riskler Arasındaki İlişki: Kurumsal Yapılara Dair Fourier Eşbütünleşme Analizinden Kanıt]

    Çiçen, Yıldırım Beyazıt

    Institutional structure and quality of management are the main elements that form the political risks. Political threats are directly linked to the institutional structure and the institutional design. Political risks increase if the government mechanisms fail. Increasing institutional quality reduces the political risks and positively impacts the financial risks. Monthly data from different indices are used to analyse the relationship between Turkey's political risks and financial risks between 2002 and 2015. According to the Fourier analysis of cointegration, there is a long-term relationship between the political and financial risks. Besides, as per the Fully Modified Ordinary Least Squares (FMOLS) findings and the Dynamic Ordinary Least Squares (DOLS) models, an increase in the political risk increases the financial risk.

    • SDG 16 · Barış, Adalet ve Güçlü Kurumlar
    AtıfScopus2WoS1OpenAlex1TR Dizin1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleYalnız künye2021Scopus SJRQ2
    In vitro Antioxidant and Cytotoxic Activities of Extracts of Endemic Tanacetum erzincanense Together with Phenolic Content by LC-ESI-QTOF-MS

    Yapıcı, İsmail; Altay, Ahmet; Öztürk Sarıkaya, Beyza; Korkmaz, Mustafa; Atila, Alptuğ; Gülçin, İlhami; Köksal, Ekrem

    In this study, phenolic composition, and in vitro biological activities of ethyl acetate (EAE) and methanol (ME) extracts obtained from the aerial parts of endemic Tanacetum erzincanense were investigated. Total phenolic and flavonoid content of the extracts were determined by Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. Antioxidant capacity of the extracts was evaluated over radical scavenging (DPPH and ABTS) and metal ion reducing power (FRAP and CUPRAC) tests. Individual phenolic compounds in ME was analyzed by high-performance liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF/MS). Cell inhibitory potential of the extracts was tested against colorectal adenocarcinoma (HT-29), breast adenocarcinoma (MCF-7), and hepatocarcinoma (HepG2) cells by 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. The results showed that ME contains higher TPC (64.4 mg GAE/g) and TFC (62.2 mg QE/g) than those of EAE (41.5 mg GAE/g and 40.0 mg QE/g). LC-ESI-QTOF/MS analysis revealed that ME is rich in phenolic compounds, namely, chlorogenic acid, apigenin, quercetin, luteolin, and diosmetin. Antioxidant assay results indicated that ME possess stronger activity than EAE and a power that competes with synthetic antioxidants. XTT assay results demonstrated that although both extracts displayed a considerable cytotoxicity against the tested cancer cell lines in a time and dose-dependent manner, ME expressed its selective inhibitory action towards MCF-7 cells with an IC50 value of 20.4 μg/mL for 72 h. These results may serve as a basis for further in vivo studies to examine the potential applications of T. erzincanense in food and pharmaceutical industries.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus27WoS24OpenAlex24
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2021Scopus SJRQ2
    Effect of using chia seed powder on physicochemical, rheological, thermal, and texture properties of ice cream

    Ürkek, Bayram

    In this study, a mixture of salep and chia seed powder (CSP) at different ratios was used as a stabilizer in the production of ice cream. The effect of the mixtures was determined on the physical, chemical, color, rheological, thermal properties, instrumental hardness, and consumer acceptance properties of the ice cream samples. The viscosity, consistency coefficient, lightness (L*), whiteness index, (Formula presented.) (midpoint and offset), heat ice freezing, and melting values increased in the sample containing 0.6% salep and 0.2% CSP compared to the control sample and then decreased in accordance with the increment of CSP. The highest hardness value was determined in the sample containing CSP (0.8%). The control sample and sample containing 0.6% salep/0.2% CSP had the highest consumer acceptance scores. It was determined that 0.2% CSP could be used with salep to decrease the consumption of orchid species and to improve various quality properties of ice creams. Practical applications: Salep (Orchidaceae family) is generally used as a stabilizer in ice cream, and species of salep is been extinction day to day. This study indicated that the usage of the mixture of salep and chia seed powder can improve the quality properties of ice creams. Consequently, the mixture of salep (75%) and chia seed powder (25%) could be used as a stabilizer to reduce using salep and to protect species of salep to improve the quality properties of ice cream.

    • SDG 2 · Açlığa Son
    AtıfScopus20WoS20OpenAlex18
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2021Scopus SJRQ3
    Evaluation of ultrasonication and agitation extraction methods at different conditions on the phenolic composition and antioxidant activities of mammillaria prolifera

    BURNAZ, NESIBE ARSLAN

    The study focuses on the comparative evaluation of extraction methods (ultrasonication and agitation) based on phenolic composition and antioxidative activities of Mammillaria prolifera and it is the first report on this subject. The effects of extraction conditions of temperature (25° and 60°), time (15, 30 and 60 min) and solvent type (water and 70 % and 100 % methanol) on total phenolic compounds, 2,2'-azinobis( 3-ethylbenzothiazoline-6-sulfonic acid) and 2,2-diphenyl-1-picrylhydrazyl anti-radical activities and ferric ion reducing antioxidant power values were determined. Moreover, the phenolic acid compositions of the extracts were investigated by high performance liquid chromatography. The extracts prepared with the ultrasonic method showed stronger antioxidant activity than those prepared with agitation methods. In both methods total phenolic compounds and antioxidant activity values were the lowest in the aqueous extracts. The results showed a positive correlation observed between total phenolic compounds and antioxidant activities of the studied extracts. The optimal conditions for the extraction of phenolic compounds from Mammillaria prolifera were found as 60 min extraction time, 60° extraction temperature and 70 % methanol concentration by using the ultrasonication method. Notably, protocatechualdehyde, gallic acid, para hydroxy benzoic acid and ferulic acid were identified in Mammillaria prolifera by using the high performance liquid chromatography-diode array detector system and 14 phenolic standards. Consequently, Mammillaria prolifera cladodes can be used in food or pharmaceutical practices, as a potential natural source of antioxidants.

    AtıfScopus6WoS6OpenAlex7
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2021Scopus SJRQ4
    Effect of different warm up protocols (deep feelings, massage, dynamic traction) on different levels of blood lactate and anaerobic power of athlete students

    Sajedi, Heidar; Bas, Mustafa; Aydın, Elif

    The aim of this study is to investigate the effect of different warm-up protocols (deep feelings, massage, dynamic traction) on different levels of blood lactate and anaerobic power of athlete students. The present study was quasi-experimental, with pre and post-test design and a control group and also three experimental groups. After announcing, 36 students who have had at least three years of professional sports experience were chosen among qualified students and they were set randomly in four groups of deep feelings, massage, dynamic traction, and control. Wingate test was used to measure anaerobic power. The 894E Monark performed the test Ergo medic as a Wingate test. The blood lactate of the participants of each group were measured in separate sessions using the German Scott Lactometer (using hand blood sample). We used two methods of petrissage and testament in the massage group. In the deep feelings group, the 11+ protocol designed by FIFA to improve performance and prevent player injury was used to warm up and five major muscles (Quadriceps femoris muscle, Hamstring, Hip flexor muscle, Hip Extensor muscle, Ankle Extensor) were stretched. The results show that there was a significant difference between the results of an anaerobic power test and blood lactate in those four groups. Based on the Tuki test and attention to the mean of post-test records compared to the pre-test, the two groups of dynamic traction and deep feelings compared to the control group had significantly welled performance in anaerobic power and blood lactate (P<0/05) and there was no significant difference in the massage group compared to the control group (P>0/05). As a result, it can be said that all three methods of warming up including dynamic traction, massage, deep feelings improve the performance of the participants in the anaerobic power and blood lactate test compared to the control group and performing the students of deep feelings and dynamic traction group in terms of anaerobic power and blood lactate is better than massage group.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2021Scopus SJRQ3
    Investigation of the removal of sulfamethoxazole drug waste from aqueous solutions under the effect of zinc oxide/montmorillonite nanocomposite by photocatalytic ozonation process

    Özyürek, Işıl Nihan; Kıranşan, Murat; Karaca, Semra

    In this study, the synergistic effect of photocatalysis and ozonation processes to degrade the sulfamethoxazole (SMX), one antibiotic pharmaceutical compound, has been studied through the influence of main operational variables such as zinc oxide/montmorillonite (ZnO/MMT) dos-age, SMX initial concentration, ozone flow rate, pH and the addition of organic and inorganic scavengers. Synthesized ZnO nanoparticles were immobilized on the montmorillonite surface to prepare ZnO/MMT catalyst as a photocatalyst. The catalyst was characterized by X-ray fluo-rescence, X-ray diffraction, scanning electron microscope, high-resolution transmission electron microscope and N2 adsorption/desorption. The highest SMX degradation efficiency (80.84% for 30 min of reaction time) was obtained for the photocatalytic ozonation process compared to adsorption, single ozonation, catalytic ozonation, and photolysis. ZnO/MMT was more effective photocatalyst according to ZnO, indicating its usability as a promising photocatalyst for the removal of organic contaminants in aqueous solutions. The reduced degradation efficiency with the addition of organic and inorganic scavengers showed the important role of the photo-produced radicals and holes as well as direct ozonation in SMX degradation. A mechanism is also proposed for photocatalytic ozonation degradation by using the gas chromatography-mass spectroscopy (GC-MS) analysis method. Finally, several by-products were identified by GC-MS analysis, which allowed to depict a possible mechanism for the sulfamethoxazole degradation.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus9WoS7OpenAlex10
    ScopusWeb of Scienceİncele