Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleYalnız künye2016Scopus SJRQ3
    Selective cytotoxic effect of Rhododendron luteum extract on human colon and liver cancer cells

    Demir, Selim; Turan, Ibrahim; Aliyazicioglu, Yuksel

    Purpose: The genus Rhododendron is distributed entirely in the world with the exception of South and Central America and Africa, growing in a large diversity of climatic conditions. This genus is a rich source of phenolic compounds, especially flavonoids, essential oils, chromones, terpenoids, and steroids. It has many biological properties such as antioxidant, anti-inflammatory, antiviral, antibacterial, anticancer, antidiabetic, immunomodulatory, cardioprotective and hepatoprotective among others due to their polyphenolic constituents. The objective of the current study was to evaluate the antioxidant properties and cytotoxic activity of dimethyl sulfoxide extract of flowers of Rhododendron luteum (DEFR) for the first time. Methods: The total polyphenolic contents (TPC), total flavonoid contents (TFC) and ferric reducing antioxidant power (FRAP) of the extract were evaluated using spectrophotometry procedures. The cytotoxic activity of the extract on three cancers (human breast, colon and liver carcinoma) and human foreskin fibroblast cells was determined using the MTT assay. Results: TPC and FRAP values were found 54.2+.0.38 mg gallic acid equivalents and 164.2±1.77 mg trolox equivalents per to g sample, respectively. R. luteum extract exhibited selective cytotoxicity against colon and liver cancer cells compared to normal fibroblast cells, while this selective cytotoxicity was not observed in breast cancer cells. Conclusion: Our results demonstrate that the Rhododendron luteum may be a great source of antioxidant and antitumor natural agents due to their capability of decreasing cancer cells proliferation.

    AtıfScopus25WoS29
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2016Scopus SJRQ1
    Systemic oxidant/antioxidant balance in human abdominal aortic aneurysm

    Menteşe, Umit; Turan, Ibrahim; Usta, Sefer; Demir, Selim; Koral, Özgür; Öztaş Menteşe, Seda; Çavuşoǧlu, Ismail Gökhan; Karahan, Süleyman Caner; Alver, Ahmet; Doǧan, Orhan Veli

    The aim of this study was to evaluate the oxidant-antioxidant balance in patients with abdominal aortic aneurysms (AAA). Forty-two consecutive patients with AAA and 46 control subjects were included. Total oxidant status (TOS) and total antioxidant status (TAS) levels were measured and the oxidative stress index (OSI) value determined. Serum TOS and OSI values in patients with AAA were higher than those in the controls (p<0.001, p<0.001, respectively). There was a positive correlation between abdominal aortic diameters, serum TOS levels (r=0.592, p<0.001) and OSI values (r=0.598, p<0.001). A cut-off value of 17.68 μmol H2O2 equivalent/L for TOS was associated with 86% sensitivity and 83% specificity and a cut-off value of 1.77 for OSI was associated with 86% sensitivity and 81% specificity for predicting AAA. Systemic oxidative imbalance develops in patients with AAA, particularly as a result of an increase in TOS.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus11WoS10OpenAlex10
    ScopusWeb of SciencePubMedİncele
  • MakaleYayıncıda açık erişim2016Scopus SJRQ3
    The effects of Co addition on the mechanical and microstructural properties of the matrix material of a Fe-based marble cutting tool

    Budak, S.; Kaplan, M.

    In this study, four different kinds of marble cutting matrices with a base composition of Fe-Cu-Sn and with variable amounts of Co powder were produced. For compaction, hot sintering process was carried out at 850°C under 35 MPa for 4 min. The mechanical and microstructural properties of the matrix materials were determined using SEM with EDS, three-point bending test, density and hardness measurement techniques. The addition of Co powders to the matrix and the subsequent hot sintering process affected the mechanical and microstructural properties of the cutting tool, such as hardness, total elongation, % porosity and phase distribution.

  • MakaleYalnız künye2016Scopus SJRQ1
    Effect of seasonal changes on the combustion characteristics of impregnated cedar (Cedrus libani A. Rich.) wood

    Fidan, M. Said; Yaşar, Ş. Şadiye; Yaşar, Mehmet; Atar, Musa; Alkan, Elif

    Wood is an irreplaceable material used as decorative and structural element both indoors and outdoors. When used as a structural material, wood has several superior characteristics in comparison to other structural constituents, although it is adversely affected by fires as well as biotic pests and abiotic effects. In this study, cedar (Cedrus libani A. Rich.) wood samples were impregnated using either Tanalith-E or Wolmanit-CB as detailed in ASTM-D 1413-76 and surface-treated using water-based or synthetic varnish. The impregnated and varnished samples were left outdoors with the aim of investigating the effect of seasonal changes. The samples were later subjected to combustion analysis as detailed in the combustion test standard ASTM-E 160-50. The results of the study indicated that the weight loss was lower during winter (87.82%), for samples that were impregnated using Wolmanit-CB (88.90%) and those that were treated with synthetic varnish (88.45%). On the other hand the O2 and CO2 contents were determined to be the highest in fall during combustion without flame (18.16% and 17.96%, respectively); the CO content was the highest during combustion without flame for the winter samples (28,907 ppm) and the NO content was the highest during combustion without flame for the spring samples (76.15 ppm). In conclusion, the winter samples that were impregnated using Wolmanit-CB and treated with synthetic varnish were determined to be safer to employ in areas with high fire risk.

    • SDG 13 · İklim Eylemi
    AtıfScopus6WoS9OpenAlex5
    ScopusWeb of Scienceİncele
  • MakaleYayıncıda açık erişim2016Scopus SJRQ1
    Organic geochemistry and element distribution in coals formed in eocene lagoon facies from the Eastern Black Sea Region,NE Turkey

    Saydam Eker, Çiğdem; Akpinar, İbrahim; Sipahi, Ferkan

    The amount and type,the inorganic element content,and the maturity of organic materials of Eocene coals,shaly coals,and coaly shales exposed in the Gümüşhane and Bayburt districts of the Eastern Black Sea Region of Turkey were investigated. The depositional environments and hydrocarbon potentials were also interpreted. The total organic carbon concentrations in the studied samples ranged from 0.50% to 63.08%. The samples from Özyurt,Kayadibi,and Tarhanas contained types II and III kerogen,and those from Sökmen and Manas contained type III kerogen. The samples contained Co,Cs,Ga,Hf,Th,U,Y,Mo,Be,Cd,Sb,and La,with average values similar to those of standard brown coals. The samples showed average contents of Co,Ga,Nb,Rb,V,Y,Cu,Pb,Zn,As,Be,and Se,similar to those of other Turkish coals. The sediment source of Eocene samples in the five areas was characterized by rocks with intermediate or mafic geochemical characteristics. The terrigenous/aquatic ratio of coal and shaly coal samples of the areas in question is >1. The sterane distribution was C29 > C28 > C27 and C29 > C27 > C28 for the Özyurt and Tarhanas areas,respectively. The average Tmax values for samples are between 424 °C and 460 °C. For samples Oz-1 and Ta-2,22S/(22S + 22R) homohopane (C32) ratios are 0.48 and 0.61,respectively; 20S/(20S + 20R) sterane (C29) ratios are 0.18 and 0.53,respectively; and Ts/(Ts + Tm) ratios are 0.015 and 0.64,respectively. The Pr/Ph ratios of the samples are >3. The studied samples have low sterane/hopane and high (C19+C20)/C23) ratios without anoxic biomarkers (17α(H)-28,30-bisnorhopane). Based on these data,the coals,shaly coals,and coaly shales were probably deposited under an oxic-suboxic mixture of marine and terrestrial environment conditions; these materials contain terrestrial organic matter and cannot generate hydrocarbon.

    AtıfScopus15WoS16OpenAlex22TR Dizin4
    ScopusWeb of ScienceTR Dizinİncele
  • BildiriYalnız künye2016
    Determination of the ground-building relationships in the KTU campus area with microtremor measurements

    Beker, Y.; Sayil, N.; Akin, O.; Coban, K.H.

    Microtremor measurement obtained by ground vibrations is one of the useful methods for determination of ground characteristics. Also the method has been using to specify building resonance risk during earthquakes in the last decades. In this study, single station microtremor recordings have been taken on the ground and at the 6 buildings in the KTU campus area. The measurements taken on the ground and in the buildings have been evaluated by Nakamura (H/V ratio) method. The eastern of the campus area presents Class-IV and the middle and western part of the campus present Class-II- Class-III according to Kanai and Tanaka ground classification. The predominant frequencies of the buildings are not in a harmony with the values of the ground. It can be deduce that the resonance risk is low for these buildings during the earthquakes. The H/V ratios of the ground change between 1-3 and lower than the buildings ratios which change between 5.0-8.5.

    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
    AtıfScopus1
    Scopusİncele
  • MakaleYalnız künye2016Scopus SJRQ1
    Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line

    Demir, Selim; Aliyazicioglu, Yuksel; Turan, Ibrahim; Misir, Sema; Mentese, Ahmet; Yaman, Serap Ozer; Akbulut, Kubra; Kilinc, Kagan; Deger, Orhan

    Cancer is a heterogeneous disease, two of whose characteristic features are uncontrollable cell proliferation and insufficient apoptosis. Various studies have investigated the antiproliferative effects of propolis, a natural bee product, from different countries, and its cytotoxic effects have been attributed to its polyphenol contents. The purpose of this study was to show the cytotoxic effects, and possible mechanisms involved, of ethanolic extract of Turkish propolis (EEP) on the human lung cancer (A549) cell line. Cytotoxic activity of EEP on A549 cells was revealed using the MTT assay. Mechanisms involved in the cytotoxic action of EEP on A549 cells were then investigated in terms of apoptosis, mitochondrial membrane potential and cell cycle using flow cytometry, endoplasmic reticulum stress using RT-PCR, and caspase activity using luminometric analysis. EEP exhibited selective toxicity against A549 cells compared to normal fibroblast cells. We determined that EEP arrested the cell cycle of A549 cells at the G1 phase, induced endoplasmic reticulum stress, caspase activity, and apoptosis and reduced mitochondrial membrane potential. These results indicate that Turkish propolis is capable of reducing cancer cell proliferation and may have a promising role to play in the development of new anticancer drugs in the future.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus102WoS105OpenAlex123
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2016Scopus SJRQ1
    A study to develop clinical decision rules for the use of radiography in wrist trauma: Karadeniz wrist rules

    Karaca, Yunus; Turkmen, Suha; Cansu, Aysegul; Baki, Mehmet Emre; Eroglu, Oguz; Tatli, Ozgur; Gunaydin, Mucahit; Beyhun, Ercument; Gunduz, Abdulkadir; Eryigit, Umut

    Introduction: The aim of this study was to evaluate patients presenting to the emergency department (ED) with wrist trauma using physical examination findings and functional tests and to identify findings with high sensitivity and specificity among the parameters assessed in patients with fracture in the wrist. The ultimate objective was thus to establish a reliable and widely usable clinical decision rule for determining the necessity of radiography in wrist trauma. Methods: This prospective, multicenter study was performed in 8 hospitals. The relation between radiologically determined fracture and clinical findings consisting of physical examination findings and functional tests was assessed in terms of whether or not these were markers of radiography requirement, with the aim of identifying predictive values for fracture. Results: A total of 603 eligible trauma patients presented to the participating EDs during the study period. Fracture was identified in 24.5% of patients (n= 148). The 4-way combination with the highest sensitivity was identified as axial compression and the positive distal radioulnar drawer test, and pain with radial deviation and dorsal flexion. Sensitivity at distal ulna palpation was added as a fifth parameter, and sensitivity and negative predictive value thus increased to 100%. Conclusion: With their 100% sensitivity and 100% negative predictive values, the Karadeniz wrist rules may represent a clinical decision rule that can be used in practice in EDs. If all 5 findings are negative, there is no indication for wrist radiography. (C) 2016 Elsevier Inc. All rights reserved.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfWoS8OpenAlex11
    Web of SciencePubMedİncele
  • MakaleYalnız künye2016Scopus SJRQ3
    Preventing Suture Extrusion and Recurrence in Mustarde and Furnas Otoplasties by Using Laterally Based Postauricular Dermal Flap, Long-Term Results

    Basat, Salih Onur; Ceran, Fatih; Askeroglu, Ufuk; Aksan, Tolga; Orman, Cagdas; Yazar, Memet; Uscetin, Ilker; Akan, Mithat; Bozkurt, Mehmet

    Background:Prominent ear deformity (PD) is an unacceptable condition of pinna that affects 5% of the population and is associated with emotional stress, behavioral disturbances, and social restrictions in relationships. Conchal hypertrphy, inadequate formation of antihelical fold, earlobe placement ahead than it should be, or various combinations of these changes are main characteristics of PD. Many surgical techniques have been described for the PD.The authors' aim was to present laterally based postauricular dermal flap combination with cartilage-sparing methods and effectiveness of this technique in suture extrusion prevention and reducing the rate of recurrence with long-term results.Methods:Forty-one patients had bilateral and 6 patients had unilateral PD, a total of 47 patients with a mean age of 14.48 were operated by using this combined procedure. A laterally based supraperichondrial dermal flap was prepared from a deepithelized elliptical postauricular incision. Mustarde and Furnas suture techniques were used solely for PD correction. The dissected laterally based dermal flap was fixed to the mastoid bone with sutures in stretched position after reshaping the auricular cartilage with sutures.Results:The average helix-mastoid distance was (mm) 16.282.36, concha-mastoid angle was 25.71 +/- 0.96 degrees on 12-month measurements. The helix-mastoid distance showed an increase of 1 to 3mm, in the concha-mastoid angle measurements of 1 degrees to 2 degrees. Statistically significant changes were observed between the average preoperative, postoperative 1. month, postoperative 12. month helix-mastoid distances (mm), and month concha-mastoid angle (degrees) measurements (P=0.0001).Conclusions:The laterally based postauricular dermal flap technique is an effective method to prevent suture extrusion and recurrence which are the most important complications of otoplasty procedure and easy to apply.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfWoS15OpenAlex15
    Web of SciencePubMedİncele
  • MakaleYalnız künye2016Scopus SJRQ2
    Mean platelet volume is related with ischemic stroke in patients with sinus rhythm

    Özkan, Bugra; Arik, Osman Z.; Gözükara, Mehmet Y.; Sahin, Durmus Y.; Topal, Salih; Uysal, Onur K.; Elbasan, Zafer; Epçeliden, Tuncay; Çayil, Murat; Gür, Mustafa

    Stroke is the leading cause of disability worldwide. It is known that atrial fibrillation and left atrial enlargement contribute ischemic stroke, and mean platelet volume (MPV) increases in patients with ischemic stroke and atrial fibrillation. We aimed to determine whether higher MPV is associated with ischemic stroke in patients with sinus rhythm. We evaluated 74 patients in sinus rhythm and with ischemic stroke (Group 1) and 90 age-matched and sex-matched healthy individuals as control group (Group 2). After physical and echocardiographic examination, 24-48 h Holter monitoring and complete blood counts were studied. There were no statistically significant differences in age, sex rates, and comorbidities between groups. Left atrial diameter was higher in Group 1 than Group 2 (P=0.001), but both were in normal range. MPV was significantly higher in Group 1 (P<0.001) and was an independent determinant [odds ratio (OR): 1.840; P<0.001; 95% confidence interval (CI) 1.330-2.545] of ischemic stroke with left atrial (OR: 1.138; P=0.006; 95% CI 1.037-1.248). In conclusion, higher MPV is associated with acute ischemic stroke in patients with sinus rhythm and without heart failure or left atrial enlargement. MPV and left atrial diameter are independent predictors of ischemic stroke in this patient population. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfWoS11OpenAlex13
    Web of SciencePubMedİncele
  • MakaleYayıncıda açık erişim2016Scopus SJRQ2
    Comparison of Effects of Separate and Combined Sugammadex and Lipid Emulsion Administration on Hemodynamic Parameters and Survival in a Rat Model of Verapamil Toxicity

    Tulgar, Serkan; Kose, Halil Cihan; Piroglu, Isilay Demir; Karakilic, Evvah; Ates, Nagihan Gozde; Demir, Ahmet; Gergerli, Ruken; Guven, Selin; Piroglu, Mustafa Devrim

    Background: Toxicity of calcium channel blockers leads to high patient mortality and there is no effective antidote. The benefit of using 20% lipid emulsion and sugammadex has been reported. The present study measured the effect of sugammadex and 20% lipid emulsion on hemodynamics and survival in a rat model of verapamil toxicity. Material/Methods: In this single-blinded randomized control study, rats were separated into 4 groups of 7 rats each: Sugammadex (S), Sugammadex plus 20% lipid emulsion (SL), 20% lipid emulsion (L), and control (C). Heart rates and mean arterial pressures were monitored and noted each minute until death. Results: Average time to death was 21.0 +/- 9.57 minutes for group C, 35.57 +/- 10.61 minutes for group S, 37.14 +/- 16.6 minutes for group L and 49.86 +/- 27.56 minutes for group SL. Time to death was significantly longer in other groups than in the control group (p<0.05). Conclusions: Verapamil overdose is has a comparatively high mortality rate and there is no effective antidote. Treatment generally involves gastric decontamination and symptomatic treatment to counteract the drug's negative effects. In animal studies sugammadex and lipid emulsion had a positive effect on survival in patients with calcium channel blocker toxicity. Sugammadex and intralipid increased survival in a rat model of verapamil toxicity. The combination of both drugs may decrease cardiotoxicity. Sugammadex alone or combined with 20% lipid emulsion reduce the need for inotropic agents. The mechanism requires clarification with larger studies.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfWoS10OpenAlex10
    Web of SciencePubMedİncele
  • MakaleYalnız künye2016Scopus SJRQ4
    MODIFIED KDIGO FOR PREDICTING MORTALITY IN ICU PATIENTS RECEIVING CONTINUOUS RENAL REPLACEMENT THERAPY FOR ACUTE RENAL FAILURE: KDIGO-URINARY OUTPUT VS. KDIGO-SERUM CREATININE LEVEL

    Tulgar, Serkan; Cakiroglu, Basri; Cevik, Banu Eler; Karakilic, Evvah; Ates, Nagihan Gozde; Gergerli, Ruken; Ozdemir, Erman

    Introduction: Acute Renal Injury (ARI) is a constant problem for patients in intensive care and Continuous Renal Replacement Therapy (CRRT) is an ever-more important part of acute renal injury (ARI) treatment. Various criteria have been used for the diagnosis and classification of acute renal failure, including RIFLE (Risk-Injury-Failure-Loss-End stage), AKIN (Acute Kidney Injury Network) and most recently KDIGO (Kidney Disease: Improving Global Outcomes). Many studies have only evaluated urinary output or serum creatinine when categorizing ARI. Our aim was to determine the predictors of mortality in intensive care patients treated with CRRT and to compare mortality with ARI level as determined by KDIGO-Serum Creatinine (KDIGO-SCr) and KDIGO-urinary output (KDIGO-UO) Materials and methods: This retrospective study was performed on intensive care patients receiving CRRT at our institute between January 2010-December 2011. Patient files were reviewed and demographic data, hospitalization time, laboratory findings, CRRT commencement and ARI levels were noted. Results: Seventy patients were included in the study. Mortality was found to be associated with patients' age, Glascow Coma Scale (GCS) score, Acute Physiology and Chronic Health Evaluation (APACHE) II score and adjusted predicted death rate. (p<0,01). Receiver Operating Curve (ROC) area under the curve was statistically significant for determination of mortality using KDIGO-SCR (p<0.01) although the same was not true for KDIGO-UO (p>0.05). Conclusions: We believe that RIFLE, AKIN, KDIGO criteria are each good predictors of mortality. In the case of KDIGO criteria, based solely on serum creatinine or urinary output, KDIGO-SCr was found to be a better predictor of mortality when compared to KDIGO-UO.

    AtıfWoS1
    Web of Scienceİncele
  • MakaleYalnız künye2016Scopus SJRQ2
    Do early procalcitonine levels aid in predicting mortality in burn patients?

    Piroglu, Isilay Demir; Tulgar, Serkan; Piroglu, Mustafa Devrim; Thomas, David Terence; Karakilic, Evvah; Gergerli, Ruken; Ates, Nagihan Gozde; Demir, Ahmet

    Aim: Burn patients in intensive care units (ICU) are at high risk of mortality. Our aim in this stuy is to evaluate the use of first 48 hour procalcitonin level (PCT), C-reactive protein (CRP) and APACHE II score for the prediction of mortality in burn patients admitted to ICU. Material and method: Files of patients with burns admitted to a tertiary centre's burn unit were retrospectively analysed and those with procalcitonin and C-reactive protein level measurements and APACHE II scores within first 48 hours of admittance were included in this study. Patients with comorbidities that would effect PCT and CRP levels such as chronic renal or liver failure were excluded from the study. Patients PCT, CRP and APACHE II scores were compared with the outcome of patients. Results: Seventy patients were included in this study. While CRP levels were lower in patients that were deceased, PCT levels were significantly higher in these patients. In patients with APACHE II score > 20 and PCT > 2 ng/ml, mortality was statistically very significantly higher compared with other patients. Logistical regression analysis showed that high PCT levels and APACHE II scores were important at predicting mortality in these patients. Conclusion: High PCT levels within 48 hours of burns is a predictor of mortality in these patients. Additional studies are required to correctly determine the cut-off value. A modified scoring system including APACHE II and PCT may be useful for better predicting mortality, although larger multi-centered studies are required.

    AtıfWoS3
    Web of Scienceİncele
  • MakaleYalnız künye2016Scopus SJRQ2
    Permo-Carboniferous granitoids with Jurassic high temperature metamorphism in Central Pontides, Northern Turkey

    Gücer, Mehmet Ali; Arslan, Mehmet; Sherlock, Sarah; Heaman, Larry M.

    In the northern part of the Central Pontides (N Turkey) there are different metamorphic rocks exposed, notably the Devrekani metamorphic rocks. Here, upper amphibolite-lower granulite facies metamorphic rocks contain predominantly paragneiss, orthogneiss and metacarbonate, and to a lesser extent, amphibolite and quartzite, with cross-cutting aplite, pegmatite and granite veins. This is the first report of these rocks and includes new data on the petrochemistry, geochronology and metamorphic evolution of the Devrekani orthogneisses from the Central Pontides. The orthogneisses show five different mineral parageneses with the characteristic mineral assemblage quartz + K-feldspar + plagioclase + biotite +/- hornblende +/- opaque (+/- ilmenite and +/- magnetite), and accessory minerals (zircon, sphene and apatite). These metamorphic rocks exhibit generally granoblastic, lepidogranoblastic and nematolepidogranoblastic with locally migmatitic and relic micrographic textures. They have well-developed centimeter-spaced gneissic banding and display gneissose structure with symmetric, asymmetric and irregular folds. The petrographic features, mineralogical assemblages and weak migmatization reflect high temperature conditions. Thermometric calculations in the orthogneisses indicate metamorphic temperatures reached 744 +/- 33 A degrees C. Field relations, petrography and petrochemistry suggest that the orthogneisses have predominantly granodioritic and some granitic protoliths, that show features of I-type, medium to high-potassic calc-alkaline volcanic arc granitoids. The orthogneisses have high contents of LILEs and low contents of HFSEs with negative Nb and Ti anomalies, which are typical of subduction-related magmas. The orthogneisses also show significant LREE enrichment relative to HREE with negative Eu anomalies (Eu-N/Eu* = 0.33-1.07) with La-N/Lu-N = 6.98-20.47 values. Based on U-Pb zircon dating data, the protoliths are related to Permo-Carboniferous (316-252 Ma) magmatism. It is likely that peak metamorphism took place during the Jurassic as reflected by the U-Pb zircon ages (199-158 Ma) and also 40Ar/39Ar from hornblende/biotite (163-152 Ma). The four biotite 40Ar/39Ar average ages from the rock samples are ca. 156 Ma, suggesting that the metamorphic rocks cooled to 350-400 A degrees C at ca. 156 Ma. Conclusively, the Devrekani metamorphic rocks can be ascribed as products of Permo-Carboniferous continental arc magmatism overprinted by Jurassic metamorphism in the northern Central Pontides.

    AtıfScopus30WoS27OpenAlex23
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2016Scopus SJRQ1
    Cenozoic forearc gabbros from the northern zone of the Eastern Pontides Orogenic Belt, NE Turkey: Implications for slab window magmatism and convergent margin tectonics

    Eyuboglu, Yener; Dudas, Francis O.; Santosh, M.; Zhu, Di-Cheng; Yi, Keewook; Chatterjee, Nilanjan; Jeong, Youn-Joong; Akaryali, Enver; Liu, Ze

    The Eastern Pontides Orogenic Belt represents one of the best examples of fossil convergent margins in the eastern Mediterranean region. However, the origin and geodynamic setting of the late Mesozoic-Cenozoic magmatism in this belt remain controversial due to lack of systematic geological, geochemical and chronological data. The general consensus is that the late Mesozoic-Cenozoic igneous activity is related to northward subduction of oceanic lithosphere in the late Mesozoic and following collision between Tauride and Pontide blocks in the early Cenozoic Here we present a comprehensive study focusing on the origin and geodynamic setting of gabbro bodies exposed along a narrow zone, parallel to the southeastern coast of the eastern Black Sea basin, in the Northern Zone of the Eastern Pontides Orogenic Belt. The studied gabbro bodies are hosted within late Cretaceous basaltic, andesitic, and dacitic volcanics including pyroclastic rocks and interbedded sedimentary rocks. The gabbro bodies range in size from 0.1 km(2) to 1.5 km(2), and outcrop patterns vary from round or elliptical to markedly elongate with sharp and discordant contact with the host rocks. Their mineral assemblage includes mainly clinopyroxene, plagioclase, minor olivine, amphibole, magnetite and rarely orthopyroxene, biotite, zircon and titanite. The occurrence of sutured grain boundaries on clinopyroxene and plagioclase, and the presence of reverse compositional zoning in clinopyroxene and olivine suggest mixing between magmas of contrasting compositions during mineral growth. Thermobarometric computations indicate that the temperature at the beginning of crystallization was similar to 1250 degrees C and crystallization was polybaric Zircon and titanite U-Pb ages indicate that these small intrusions were emplaced into crustal rocks of the Eastern Pontides Orogenic Belt during Lutetian (45 +/- 2 Ma). The depletion of HFSE is consistent with the involvement of an arc-related source in the petrogenesis of these rocks, and low to moderate enrichment Ce, Rb, Ba, K, Pb, Sr and Th suggests that involvement of subducted oceanic sediment was modest. The low Th content and low Th/Yb indicate that the role of sediment addition was nevertheless limited. The Nd, Sr and Pb isotopic data are consistent with the interpretation that the dominant source component in these gabbros is a depleted, peridotitic mantle, and that crustal contamination is relatively unimportant. We suggest that mafic magmas that produced the gabbroic intrusions were derived from melting of a depleted mantle source under the forearc region of the Eastern Pontides Orogenic Belt during southward subduction of two oceanic plates separated by a mid-ocean ridge, leading to the formation of a slab window. We also infer fractional crystallization and assimilation during both magma storage in the crust-mantle transition zone and transfer into the overlying arc crust. (C) 2015 International Association for Gondwana Research. Published by Elsevier B.V. All rights reserved.

    AtıfScopus57WoS51OpenAlex60
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  • MakaleYalnız künye2015Scopus SJRQ3
    On- pump koroner arter baypas greftlemede miyokarde nfarktüsü ile iskemi modifiye albüminin ilişkisi

    Usta, Sefer; Doğan, Orhan Veli; Doğan, Süheyla; Demirbaş, Mine; Karahan, Süleyman Caner; Kılıç, Aşkın; Menteşe, Ümit; Aykan, Ahmet Çağrı; Turan, İbrahim; Demir, Selim

    Background:&shy; This study aims to evaluate the potential ofischemia-modified albumin (IMA) to predict the myocardialinfarction in on pump coronary artery bypass grafting(ONCABG) patients.Methods: Fifty elective isolated ONCABG patients (41 males,9 females; mean age 66 years; range 56 to 75 years) were includedin the study. Patients were divided into perioperative myocardialinfarction (PMI; n=8) and non-infarction (NPMI; n=42) groupsaccording to perioperative cardiac troponin I (cTnI) values andECG findings. Serum IMA levels were measured preoperatively,20 minutes after aortic cross clamping, 30 minutes, at 3, 6,12 and 24 hours after declamping.Results:&shy; Compared to the NPMI group, the declamping 30minutes, 3, 6 and 12 hours IMA levels were higher in the PMIgroup (p=0.002, p=0.048, p=0.023, p=0.007, respectively). Inboth NPMI and PMI groups, the 20 minutes after aortic crossclamping IMA levels were higher compared to the preoperativeIMA levels (p=0.0001, p=0.038, respectively).Conclusion:&shy; Our study results show that IMA may be anearly marker of myocardial infarction in the ONCABGpatients.

    AtıfTR Dizin3
    TR Dizinİncele
  • MakaleYalnız künye2015
    Çerçeveleme teorisi ve toplumsal hareketler

    Güran, Mehmet Salih

    Toplumsal gerçekliğin inşasında yapı taşları olarak kullanılan iletişim çerçeveleri,bu süreç içinde kendilerine etkin roller biçen toplumsal gruplar ve toplumsal hareketler içinanlaşılması ve denetlenmesi şart olan dinamiklerin odağında yer almaktadır. Toplu eylemçerçevelerinin, kendilerini ortaya çıkaran kültürel faktörlerle birlikte ve özellikleriyle tanınması,bunların üretilip yayılıma sokulmasında etkin olan süreçlerin tanınması ve bu süreçlerintoplumsal hareketin diğer süreçleriyle etkileşimleri, toplumbilim ve siyaset bilim açısındanönemli süreçleri oluşturmaktadır. Bu nedenle çerçeveleme analizi, sosyoloji, sosyal psikoloji,siyaset bilim ve medya araştırmalarında toplumsal hareketleri ve sivil toplum kuruluşlarını daiçeren organizasyonların etkinliklerini inceleyen araştırmalar için de stratejik bir ittifak temelioluşturmaktadır. Bu araştırmanın amacı, çerçeveleme araştırmalarının toplumsal hareketleralanında hem uygulayıcılara (yani kanaat önderlerine) medya aracılığıyla iletişim sürecindesağlayabileceği denetleme imkânlarına, hem de toplumsal hareketleri odağına alan araştırmalarasunduğu analiz imkânlarına dikkati çekmektir.

    AtıfTR Dizin7
    TR Dizinİncele
  • MakaleYalnız künye2015
    Anaakım Türk medyasının başarısızlığı: Türk gazetelerinin internet versiyonlarının bir çerçeveleme karşılaştırması

    Güran, Mehmet Salih; Özarslan, Hüseyin

    The objective of this study is to define the notion of mainstream/professional journalism bycomparatively exploring the historical conditions of media systems development to contrast itwith the infrastructure of political culture and professional culture of the past century inTurkey. After this theoretical background, we implemented a comparative framing analysis ofan actual policy debate in the Turkish press to conclude on the changing and not changingconditions that prevail in the politics/media system and culture. In the light of the framinganalysis, we found that the current state of the Turkish media system constitutes still a mostlydysfunctional social interaction platform that is caught between media parallelism andtabloidization and represents a largely underdeveloped professionalism that is still insufficientfor the deve lopment of a civil society. Nonetheless, we found on the other hand that thefundamental values and notion of mainstream media is still represented to make hope for afuture development towards a functioning media system.

    AtıfTR Dizin1
    TR Dizinİncele
  • MakaleYalnız künye2015
    Design and optimization of chemical mixing system for vacuum chambers base of simulation results

    Ünker, F.; Kaplan, E.; Çuvalcı, O.

    Computational fluid dynamics (CFD) is widely used in device design to determine gas flowpatterns and turbulence levels. CFD is also used to simulate particles and droplets, which aresubjected to various forces, turbulence and wall interactions. These studies can now beperformed routinely because of the availability of commercial software containing highquality turbulence and particle models. In order to understand how the gas is brought down towafer, it is necessary to have a knowledge of the gas flow behavior very early in t he designspiral of the Tantalum nitride - Atomic layer deposition ( TaN- ALD) chamber by undertakingparametric investigation of the interaction effect between gas flow and the funnel structure.This paper presents such a parametric investigation on a generic TaN- ALD chamber usingCFD. The results presented have been analyzed for a total of 11 different cases by varyingneck and nozzle angles for a process gas. The gas flow was mainly investigated for the nozzleangles of 4.5&amp;#61616; , 9&amp;#61616; , 12&amp;#61616; and 20&amp;#61616; and the film thi ckness results were compared with numericalflow patterns. CFD simulations using the turbulence model in ANSYS Fluent v.13 areundertaken. The parametric study has demonstrated that CFD is a powerful tool to study theproblem of gas flow structure interaction on funnel and is capable of providing a means ofvisualizing the path of the gas under different operating conditions .

  • MakaleYalnız künye2015
    Design of quartz chemical delivery parts for high temperature vacuum chambers base of simulation results

    Kaplan, Erdar; Ünker, Faruk; Çuvalcı, Olkan

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