Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Dastan, Buket(2)
- Deger, Muslim Dogan(2)
- Demirkiran, Engin Denizhan(2)
- Demírag, Hatice(2)
- Göger, Berrin(2)
- Hintistan, Sevilay(2)
- Kulakaç, Nursen(2)
- Madendere, Serdar(2)
- Uzun, Sevda(2)
- Yildiz, Huseyin Alperen(2)
- Acarer, Ahmet(1)
- Akpinar, Damla(1)
- Aktepe Cosar, Dilan(1)
- Araca, Ceyhun(1)
- Asik, Olgun(1)
- Aydin, Merve(1)
- Aykan, Ahmet Cagri(1)
- Bayrak, Nurten Gulsum(1)
- Bitirgen, Mehmet(1)
- Bulut, Rukiyye(1)
- Cin, Aynur(1)
- Colakoglu, Zafer(1)
- Cín, Aynur(1)
- Demir, Selim(1)
- Demirag, Hatice(1)
- Demirbas, Mine(1)
- Dogan, Orhan Veli(1)
- Dogan, Suheyla(1)
- Dogramaci, Seniz(1)
- Ekmekçi, Ozlem Balca(1)
- Erayman, Ibrahim(1)
- Híntístan, Sevilay(1)
- Imamoglu, Melih(1)
- Inan, Halil Ibrahim(1)
- Kahriman, Ilknur(1)
- Kandemir, Bahar(1)
- Karahan, Suleyman Caner(1)
- Karakaya, Hanife(1)
- Kazak, Aysun(1)
- Kiliç, Askin(1)
Yayınlar
- MakaleAçık Erişim2025The Effect of Hemodialysis Patients' Attitudes Towards Dietary Treatment on Dialysis Symptoms: A Randomized Controlled Clinical Study
Aktepe Cosar, Dilan; Demírag, Hatice
Objective: This study was conducted to determine the effect of hemodialysis patients' attitudes towards diet therapy on dialysis symptoms. Methods: The data of the randomized controlled study were collected from experimental (n=30) and control groups (n=30) at G & uuml;m & uuml;& scedil;hane Province Kelkit State Hospital between 1 November 2023 and 1 January 2024. Institutional and ethics committee permissions were obtained before the study. The experimental group patients were given training on diet therapy. Patient information form, hemodialysis patients' attitude scale towards diet therapy (HDTO) and dialysis symptom index (DSI) were used to collect data. Data collection tools were applied before the study (pre-test), after the training was given (intermediate measurement) and one month later (post-test). The data were analyzed using the chisquare, repeated measures ANOVA test and independent groups t-test in the SPSS 25.0 package program. Results: It was determined that the post-training measurements (intermediate measurement) of the total HDTO and sub-dimensions score averages of the hemodialysis patients in the experimental group were higher than the pre-training (pre-test) measurements; and the measurements made 1 month after the training (post-test) were lower than the measurements made immediately after the training (intermediate measurement) (p<0.05). Again, the post-training measurements (intermediate measurement) of the DSI score averages of the experimental group of patients were lower than the pre-training (pre-test) measurements (p<0.05); it was determined that the measurements made 1 month after the training were given (post-test) did not differ from the measurements made immediately after the training (intermediate measurement) (p>0.05). Conclusion: In line with the findings, it was determined that the diet therapy training provided increased hemodialysis patients' attitudes towards diet therapy and reduced dialysis symptoms.
- MakaleYayıncıda açık erişim2025A new method for the evaluation of cervical dystonia
Karakaya, Hanife; Colakoglu, Zafer; Acarer, Ahmet; Ozkurt, Ahmet
Objectives: The study aimed to develop a measurement method that yielded objective data for the clinical assessment of cervical dystonia using a Kinect camera system. Patients and methods: This double-blind, parallel-group method development study included 22 patients with cervical dystonia (3 males, 19 females; mean age: 47 years; range, 34 to 60 years) and 20 healthy individuals (13 females, 7 males; mean age: 32 years; age range, 22 to 65). Using cameras and a computer software, the head-neck postures of 40 healthy participants were recorded in the virtual environment. Using the device, 22 patients with cervical dystonia were examined both at rest and while moving with different parts of the body. Two different experts evaluated and scored the cases using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and the Tsui scale. Results: A three-way comparison revealed interclass correlations between the coefficients of 0.799 (79.9%) and 0.784 (78.4%) for at rest and with movement, respectively. The two-way comparison of the experts revealed correlation coefficients of 0.717 (71.7%) and 0.692 (69.2%) for at rest and with movement, respectively. A three-way comparison of the device and Expert 1 and Expert 2 TWSTRS scores revealed interrater agreement values of 0.6 and 0.8 (good) and 0.6 and 0.8 (good) while at rest and with movement, respectively. A three-way comparison of the device and Expert 1 and Expert 2 Tsui scores revealed interrater agreement values of 0.6 and 0.8 (good) and 0.4 and 0.6 (moderate) while at rest and with movement, respectively. Conclusion: The newly developed system was a sensitive tool for use in the kinematic evaluation of patients with cervical dystonia and could prove beneficial in diagnosis and treatment follow-up.
- DüzeltmeAçık Erişim2025The Relationship Between Thirst Distress and Severity and Compliance with Fluid Control and Interdialytic Weight Gain in Hemodialysis Patients (vol 13, pg 129, 2025)
Cin, Aynur; Demirag, Hatice; Dastan, Buket; Hintistan, Sevilay
- MakaleAçık Erişim2025The Relationship Between Thirst Distress and Severity and Compliance with Fluid Control and Interdialytic Weight Gain in Hemodialysis Patients
Cín, Aynur; Demírag, Hatice; Dastan, Buket; Híntístan, Sevilay
knowledge scores and FCHPS subscale attitude scores, and IDWG and FCHPS subscale attitude scores. A positive correlation was also found between the VAS score and IDWG. Conclusion: Thirst distress was higher than the moderate level in HD patients, and IDWG increased as thirst severity (VAS score) increased.knowledge scores and FCHPS subscale attitude scores, and IDWG and FCHPS subscale attitude scores. A positive correlation was also found between the VAS score and IDWG. Conclusion: Thirst distress was higher than the moderate level in HD patients, and IDWG increased as thirst severity (VAS score) increased.
- MakaleAçık Erişim2025First Aid Self-efficacy in Mothers of Children Aged 0-4 Years: The Gümüşhane Example
Göger, Berrin; Kahriman, Ilknur; Çolak, Bahar
Introduction: The high relationship between the effective application of first aid after home accidents and survival determines the priorities in first aid. Childcare is mostly the responsibility of mothers, and their knowledge and practices regarding the management of home injuries are crucial in reducing morbidity and mortality associated with home accidents. This study aimed to examine the first aid self-efficacy of mothers with children aged 0-4 years to manage their children's home accidents. Methods: This cross-sectional study, focusing on the first aid self-efficacy of mothers with children aged 0-4 for home accidents, was conducted with 266 mothers at a district government hospital affiliated with the Ministry of Health in the Eastern Black Sea Region between January 1, 2023, and August 1, 2023. Data were collected through a demographic information form and the first aid self-efficacy scale for home accidents. Results: The mean score of the first aid self-efficacy scale in home accidents was found to be 2.15 +/- 0.95 and significant differences were found according to the mother's level of education, number of children, income status, caregiver of the child and mothers' first aid status. Conclusion: In conclusion, the findings of the study showed that first aid self-efficacy is not based solely on demographic factors, but instead may be shaped more by education, experience and the general approach of parents as parents, although mothers' knowledge of first aid was below average.
- MakaleAçık Erişim2024The Effect of Conjunctiva-Müller Muscle Resection on Tear Oxidative Stress Levels in Patients with Blepharoptosis
Sert, Seda; Araca, Ceyhun; Mergen, Burak; Ekmekçi, Ozlem Balca
Objectives: To examine changes in tear oxidative stress levels and tear film functions in patients with blepharoptosis and dermatochalasis following conjunctiva-M & uuml;ller muscle resection (CMMR) and blepharoplasty surgeries. Materials and Methods: This prospective study included 32 healthy controls and 62 patients with blepharoptosis or dermatochalasis. CMMR surgery was performed in 20 eyes and upper blepharoplasty was performed in 42 eyes. Tear oxidative stress markers (8-hydroxy-2'-deoxyguanosine [8-OHdG3 and 4-hydroxy-2-nonenal [4-HNE3) were quantified by enzyme -linked immunosorbent assay and tear film functions were evaluated preoperatively and at 1 and 6 months postoperatively. The same assessments were performed in the control group at the same time points. Results: Preoperative tear 8-OHdG and 4-HNE levels were lower in healthy controls (52.8 +/- 13.5 ng/mL and 27.8 +/- 6.4 ng/mL, respectively) compared to patients with dermatochalasis (86.1 +/- 37.2 ng/mL and 29.8 +/- 11.1 ng/mL, respectively) and blepharoptosis (90.4 +/- 39.3 ng/mL and 43.1 +/- 4.2 ng/mL, respectively) (p<0.001). 8-OHdG levels were increased at 1 month after CMMR, while both markers were decreased 1 month postoperatively in the blepharoplasty group (p=0.034). Schirmer 1 and OSDI scores did not change throughout the visits in both patient groups, but a temporary decrease in tear break-up time (TBUT) was observed after CMMR (p=0.017). Conclusion: Dermatochalasis and blepharoptosis were associated with higher tear oxidative stress levels. CMMR surgery caused a temporary decrease in TBUT scores and an increase in oxidative stress in the first postoperative month.
- MakaleAçık Erişim2022Investigating the Relationship Between Digital Game Addiction and Sleep Quality in Adolescents
Tuncay, Birgul; Göger, Berrin
Objective: This study aimed to assess the digital game addiction and sleep quality in adolescents and examine the relationship between them. Materials and Methods: This descriptive study was conducted with 312 students from three high schools located in a district center in the Eastern Black Sea Region, who agreed to participate in the study. Data were collected using the descriptive information form, the digital game addiction scale, and the Pittsburgh sleep quality index. Results: The mean age of the participants was 15.99 +/- 0.85 years. Of the participants, 78.5% played digital games on computers, mobile phones, tablets, or game rooms. The mean score of the participants on the digital game addiction scale was 12.46 +/- 5.57; 16.3% were game addicts. The Pittsburgh sleep quality index mean score was 4.72 +/- 2.53, with a score range of 0-13; 34.9% had poor sleep quality. Conclusion: In conclusion, a positive, low-level, statistically significant relationship was found between the digital game addiction scale and Pittsburgh sleep quality index scores (r=0.157, p <= 0.001). As the digital game addiction scores increase in adolescents, their sleep quality scores also increase. Game addiction and sleep-related problems in adolescents can negatively affect their physical and psychological health and academic success. Adequate supervision and protective measures are required to reduce the problems faced by adolescents when using digital technology.
- MakaleAçık Erişim2022Clinical Preferences of Turkish Urologists in Screening and Diagnosis of Prostate Cancer and Adherence to European Association of Urology Guidelines
Yildiz, Huseyin Alperen; Demirkiran, Engin Denizhan; Madendere, Serdar; Deger, Muslim Dogan
Objective: To compare the clinical preferences of urologists in prostate cancer screening and diagnosis with current guideline recommendations.Materials and Methods: The study is based on an online survey that consists of 21 single response or multiple response questions. By e-mail, 2,305 certified urologists in active practice as well as urology residents in their last year of training were invited to participate in the study. Descriptive statistics were used to analyze practice patterns and demographics. The respondents were divided into groups based on their experience in urology, hospital type and academic title.Results: Our results show that preferences of the majority of urologists conflicts with recommendations of European Association of Urology Prostate Cancer Guidelines regarding prostate biopsy method, management of a patient with high prostate-specific antigen value, use of additional test and performance scoring systems, role of multiparametric prostate magnetic resonance imaging.Conclusion: Urologists act in the direction of their habits or clinical experience rather than current guidelines regardless of their experience. Both clinicians and professional organizations should work on what can be done about the reflection of rapidly changing scientific knowledge on the field and the improvement of the health service provided.
- MakaleAçık Erişim2022Anxiety, Motivation, Stress Levels and Associated Factors Among University Students in the COVID-19 Pandemic
Sahin, Ceyda Uzun; Aydin, Merve; Kulakaç, Nursen
BACKGROUND/AIMS: The global coronavirus disease (COVID-19) pandemic affects society seriously in terms of psychosocial aspects, but this effect is more intense on some specific population groups. University students are among the most affected population groups by the pandemic. This study was conducted to determine the anxiety, motivation, stress levels, and associated factors among health science students during the COVID-19 pandemic. MATERIALS AND METHODS: The population of this descriptive and cross-sectional study consisted of students studying at health-related departments in three universities in Turkey. The data were collected from 855 students determined by the stratified sampling method using the online survey method. A questionnaire developed by the researchers and the Beck Anxiety Inventory (BAI) were used to collect the data. Percentage, mean, standard deviation, t-test, One-Way ANOVA test, Pearson correlation, and linear regression analysis were performed to evaluate the data. RESULTS: The results revealed that the mean age of the students was 20.85 +/- 2.37 years (min: 18; max: 41), 80.5% were women, 38.0% were nursing students, 13.7% had a family member with the diagnosis of COVID-19. The BAI mean score was found to be 29.00 +/- 7.8. According to the multiple linear regression analysis, the factors affecting students' anxiety scores significantly were being female, impaired sleep and nutrition patterns, decreased motivation, increased stress level and having a family member with the diagnosis of COVID-19. CONCLUSION: Health science students experience severe anxiety due to COVID-19 pandemic and have moderate motivation and stress scores. Being a woman, having impaired sleep and nutrition patterns, reduced motivation, increased stress level and a family member diagnosed with COVID-19 are factors influencing the level of anxiety.
- MakaleAçık Erişim2022The Evaluation of Child Sexual Abuse: Child Advocacy Center Example
Bayrak, Nurten Gulsum; Akpinar, Damla; Top, Fadime Ustuner; Uzun, Sevda
Objective: The purpose of the research was to evaluate the child sexual abuse cases admitted to the Child Advocacy Center (CAC) in terms of the child, family, and abuser, and to identify the associated factors. Method: The data were collected retrospectively and descriptively from the cases in the CAC using the juridical reports, family interview reports Provincial Directorate of Family and Social Policies representative reports and the data collection form developed by the researchers. Results: Within the scope of the research, 175 child victims of sexual abuse were evaluated According to this; the mean age of the abused children was in the study was 13.33 +/- 3.33, 81.7% were girls, and 42.9% were high school students. According to the results of the study, 34.3% of the children were diagnosed with mental illness. Among the mothers and fathers included in the study, 76% of the mothers and 33.7% of the fathers are not working and also 85.1% of the mothers and 79.5% of the fathers are primary school graduates. In addition, 60% of families have a low income level. It was determined that 57.7% of the children were exposed to abuse many times and irregularly, 40.6% were exposed to sexual touching, 35.4% were exposed to penetration, and 44% medical examination. Conclusion: The study showed that family dynamics play a pivotal role in the sexual abuse of children, and low socio-economic/education level and being an adolescent girl is among the significant factors.
- MakaleAçık Erişim2022The Relationship between the Use of Complementary and Alternative Medicine in Cardiovascular Diseases with Self- Care Ability and Life Quality
Kulakaç, Nursen; Uzun, Sevda; Sayilan, Aylin Aydin
BACKGROUND/AIMS: Cardiovascular diseases are one of the leading global causes of morbidity and mortality. Lifestyle changes are critical for the prevention of cardiovascular diseases and improving self-care levels during treatment. This study aimed to explore the relationship between the use of complementary and alternative medicine (CAM) and the quality of life and self-care ability in individuals with cardiovascular disease.MATERIALS AND METHODS: The study population in this cross-sectional and correlational research consisted of cardiovascular patients hospitalized in a public hospital between 1st April and 30th June 2018. One hundred and six patients agreeing to participate in this study were selected for sampling. A Patient Information Form, the Exercise of Self-Care Scale, and the World Health Organization Quality of Life Scale-Short Form were employed as the data collection tools.RESULTS: The mean age of the patients in this study was 62.83 +/- 1.40 years, 59.4% were women, and 34.0% had coronary heart disease. The patients' mean self-care score was 101.18 +/- 22.31, and their mean quality of life score was 28.61 +/- 9.50. Age, education, diagnosis and duration of disease, constipation, and CAM use were found to affect their quality of life (p<0.005). A positive correlation was determined between CAM use and self-care ability.CONCLUSION: The use of CAM in individuals with cardiovascular disease has a positive effect on self-care ability and enhances their quality of life.
- Derleme MakaleAçık Erişim2021Current Status of Forage Crops Cultivation and Strategies for the Future in Turkey: A Review
Tan, Mustafa; Yolcu, Halil
Forage crops cultivation area in Turkey is 2.312 million ha in 2020. The rate of forage cultivation in the total agricultural area is 6.1%, and its rate in the field land is 12.3%. Lucerne, silage corn, oat, vetch, and sainfoin are main forage crops in Turkey. The amount of produced is 16.8 million tons of hay and 48.8 thousand tons of seeds. The forage crop cultivation areas have increased by 206% since the beginning of the 2000s due to the government subsidies. However, shortage of quality roughage is still a big problem for animal husbandry of the country. For this reason, new strategies should be developed to increase forage cultivation areas by considering global warming, drought, and climate change. In order to meet the need for roughage, it is necessary to expand the cultivation area of forage crops as winter catch crops and second crops. In addition, some of the fallow fields should be utilized by growing drought-resistant forage species. The fields abandoned due to different problems should be used for the cultivation of suitable forage crops.
- MakaleAçık Erişim2021Spatial Data Model for Rural Planning and Land Management in Turkey
Inan, Halil Ibrahim
In Turkey, in the areas of rural planning and land management, problems regarding data retrieval, data quality, implementation scenario and legal base (law or regulation) have long been experienced. In this study, in order to contribute to resolving such problems, a conceptual/semantic data model was designed which focuses on the definition of required data, determination of their basic qualities and also their relations. As the preparation step for the model development, interviews, and discussions with authorized people were carried out. In addition, for the definitions of the data in the model, the Land Parcel Identification System and Infrastructure for Spatial Information in the European Community (INSPIRE) are considered. For the model design, an object-oriented modelling method with the Unified Modelling Language (UML) notation was used. In the model, planning activities were focused on. It is envisaged that the model will guide work for the preparation of a technical regulation which may enable a standardized implementation throughout Turkey. It has also the potential to be an example for the implementation of laws related to spatial data both in Turkey and also worldwide.
- MakaleAçık Erişim2021Urologists' Role and Attitude in the Systemic Treatment of Urologic Cancers
Madendere, Serdar; Deger, Muslim Dogan; Demirkiran, Engin Denizhan; Yildiz, Huseyin Alperen
Objective: The goal of this study was to investigate Turkish urologists' role and attitude toward the systemic treatment of urologic cancers. Materials and Methods: An 18-item survey was e-mailed to 2305 certified Turkish urologists. The survey included questions designed to evaluate urologists' knowledge of chemotherapy procedures and their ability to manage complications, as well as how many of them perform systemic therapies and believe urologists should perform these therapies for urologic cancers. Results: We evaluated 305 responses. Most urologists (89.6%) perform hormonotherapy for prostate cancers. Further, the majority refer patients to medical oncologists for chemotherapy. Moreover, 65.9%, 70.8%, and 72.1% of the urologists believe that only medical oncologists should deliver chemotherapy for prostate, bladder, and testicular cancers, respectively. Only 23.9% of urologists believe they are competent to perform chemotherapy, while 16.7% believe they are capable of dealing with chemotherapy complications. Conclusion: Turkish urologists have a lack of performance and interest in administering systemic therapies in urologic cancers. We want to emphasize that urology is more than just surgery. Urologists should be involved in all stages of cancer treatment.
- MakaleAçık Erişim2021Investigating Hepatitis C, D and HIV Prevalance in Cases with Positive Hepatitis B Virus Antigen in a Tertiary Hospital and Examining Anti-HDV Positive Cases
Kurt, Esma Kepenek; Bulut, Rukiyye; Kandemir, Bahar; Erayman, Ibrahim; Bitirgen, Mehmet; Tasbent, Fatma Esenkaya
Objectives: Hepatitis B infection has a faster and more progressive course in the presence of hepatitis C virus (HCV), HDV and human immunodeficiency virus (HIV) infections. The aim of this study was to determine anti-HCV, anti-HDV and anti-HIV prevalance in hepatitis B surface antigen (HBsAg) (+) positive patients and to examine patients with positive anti-HDV. Materials and Methods: Data were obtained through scanning hepatitisB patient follow-up files and the hospital automation system. Descriptive data was expressed in numbers and percentages (%). Results: Mean age of 1829 HBsAg positive patients was 42.65 +/- 14.83 (7-95) and 1099 (60.1%) were male and 730 (39.9%) were female. 30 patients (1.64%) had anti-HCV and 28 patients (1.53%) had anti-HDV while 1 patient (0.055%) had positive anti-HIV. The mean age of the patients with positive anti-HDV was 53.16 +/- 15.46 and 12 of these (42.9%) were female and 16 (57.1%) were male. Fifteen HDV positive patients were given peginterferon and 10 patients had relapse and 4 patients had hepatocellular cancer during the follow-up. A patient died due to the quick progression of the disease after deciding upon transplantation. Conclusion: Patients should also be scanned for hepatitis C, D and HIV in the presence of hepatitis B infection and the patient should be followed up and treated accordingly if coinfection is detected.
- Derleme MakaleAçık Erişim2020Vaccination Studies Against COVID-19 Agent: Current Status
Hintistan, Sevilay; Kazak, Aysun
The emergence of the new pathogenic viral strains is a constant threat to global health. The latest new coronavirus strain coronavirus-2019 (COVID-19) is the best-known example of this. COVID-19, caused by the severe acute respiratory syndrome-CoV-2 virus has quickly spread around the globe. The applications of drug and vaccine practices, and the identification of potential candidates are of high importance against this pandemic. On healthy adults, a proper evaluation of potential vaccines in parallel with vaccination studies on animal models and an enlargement of production capacity will benefit minimum risk and accelerated COVID-19 vaccine studies for human subjects. The purpose of this review is to contribute to the analysis of vaccine development strategies, vaccine development stages, phase studies and the difficulties, production stages and current status of potential vaccine studies developed to prevent COVID-19.
- MakaleYayıncıda açık erişim2020Complementary and Alternative Medicine Methods Used for Sleep Disturbance in Menopause
Özcan, Handan; Çakmak, Suzan; Salman, Ebru
Objective: One of the most common complaints observed during the menopausal period is sleep disorders, affecting 40%-60% women. In this study, we aimed to determine complementary and clternative medicine (CAM) for menopausal women experiencing sleep disturbances, and the prevalence and influencing factors of sleep disturbance. Materials and Methods: In this descriptive cross-sectional study, we included menopausal women experiencing sleeplessness [>= 4 degree of discomfort according to the Visual Analog Scale (VAS)] (n=201). A questionnaire and the CAM Scale were used to collect data. The necessary institutional and ethical committee permissions were obtained. Results: The mean age of the menopausal women was 47.23 +/- 4.53 [minimum (min)- maximum (max), 30-60] years, and their mean VAS for insomnia was 5.20 +/- 1.12 (min-max, 4-9). The following methods were used by the women to overcome insomnia: herbal supplements (96.6%), dietary supplements (98.8%), religious practices (95.7%), and mind-body practices (76.9%). The most common methods were fruits and vegetables, milk and dairy products, honey, linden tea, rosehip, prayer, pray, and music. Approximately 70.5% women expressed that the method they used was effective. Conclusion: Almost all menopausal women used any method of CAM. Further studies on the effectiveness of these methods as well as the training to be provided and the information dissemination by healthcare professionals are recommended.
- MakaleAçık Erişim2020The Value of Cardiotrophin-1 in the Diagnosis, Severity, and Prognosis of Pulmonary Embolism
Pasli, Sinan; Asik, Olgun; Imamoglu, Melih; Çiçek, Mustafa; Yadigaroglu, Metin; Dogramaci, Seniz; Mentese, Ahmet; Sahin, Mursel; Tatli, Ozgur
Aim: Pulmonary embolism (PE) is a life-threatening condition that requires early diagnosis and treatment. There is still a need for precise and non-invasive biomarkers that can be used to diagnose PE. This study aimed to determine the diagnostic value of Cardiotrophin-1 (CT-1) in patients with acute PE and ascertain the relationship between serum CT-1 level and disease prognosis and severity. Materials and Methods: In this prospective study, the serum CT-1 levels of 165 patients with suspected acute PE were measured. The patients were divided into two groups, PE (+) and PE (-), based on their computed tomography angiography results. Their serum CT-1 levels were compared. Results: The CT-1 levels of the PE (+) group (median=4.18 pg/mL, range=3.57-9.55 pg/mL) was non-significantly (p=0.08) different from those of the PE (-) group (median=4.38 pg/mL, range=3.57-51.64 pg/mL). Based on the severity of the condition, there were significant differences (p=0.001) in the CT-1 levels of the patients in the intermediate-low risk group (median=4.19 pg/mL, range=3.62-5.32 pg/mL), intermediate-high risk group (median=4.06 pg/mL, range=3.57-9.31 pg/mL) and high risk group (median=5.01 pg/mL, range=3.89-9.55 pg/mL). Based on the clinical course, the CT-1 levels of the patients in the good clinical course group (median=4.15 pg/mL, range=3.57-9.31 pg/ml) were significantly different (p=0.004) from those in the poor clinical course group (median=4.53 pg/mL, range=3.66-9.55 pg/mL). Conclusion: CT-1 level was not observed to be a precise biomarker for the diagnosis of acute PE. However, our study demonstrated that the serum CT-1 levels can be used as a biomarker for ascertaining the severity and prognosis of patients with PE.
- MakaleYalnız künye2015The relationship between ischemia-modified albumin and myocardial infarction in on-pump coronary artery bypass grafting
Mentese, Umit; Dogan, Orhan Veli; Dogan, Suheyla; Turan, Ibrahim; Usta, Sefer; Demirbas, Mine; Aykan, Ahmet Cagri; Kiliç, Askin; Demir, Selim; Karahan, Suleyman Caner
Background: This study aims to evaluate the potential of ischemia-modified albumin (IMA) to predict the myocardial infarction in on pump coronary artery bypass grafting (ONCABG) patients. Methods: Fifty elective isolated ONCABG patients (41 males, 9 females; mean age 66 years; range 56 to 75 years) were included in the study. Patients were divided into perioperative myocardial infarction (PMI; n=8) and non-infarction (NPMI; n=42) groups according to perioperative cardiac troponin I (cTnI) values and ECG findings. Serum IMA levels were measured preoperatively, 20 minutes after aortic cross clamping, 30 minutes, at 3, 6, 12 and 24 hours after declamping. Results: Compared to the NPMI group, the declamping 30 minutes, 3, 6 and 12 hours IMA levels were higher in the PMI group (p=0.002, p=0.048, p=0.023, p=0.007, respectively). In both NPMI and PMI groups, the 20 minutes after aortic cross clamping IMA levels were higher compared to the preoperative IMA levels (p=0.0001, p=0.038, respectively). Conclusion: Our study results show that IMA may be an early marker of myocardial infarction in the ONCABG patients.
- DergiTURKISH JOURNAL OF NEUROLOGY