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- MakaleYalnız künye2020Process for production of microencapsulated anthocyanin pigments from Rosa pimpinellifolia L. fruits: optimization of aqueous two-phase extraction, microencapsulation by spray and freeze-drying, and storage stability evaluation
Odabas, Halil Ibrahim; Koca, Ilkay
Rosa pimpinellifolia L. fruits (RPF) are promising source of anthocyanin pigments. The objectives of this study were to optimization of the aqueous two-phase extraction (ATPE) process of anthocyanin from RPF and microencapsulation of anthocyanin-rich RPF extract. The optimal ATPE conditions were as follows: 0% HCl, 30% ethanol, 19% ammonium sulfate, and liquid to solid ratio 51.71, 97.71 min, and 30 degrees C extraction temperature. Predicted anthocyanin yield at the optimum conditions was 1578.90 mg cyanidin 3-glucoside equivalent/100 g dry fruit. ATPE resulting in 1.80-fold increase in the purity of anthocyanins when compared to conventional solvent extraction (CSE). The composition of the anthocyanins were determined with HPLC-QTOF-MS. Freeze-drying and spray-drying methods were employed for the production of microencapsulated anthocyanin pigments. The half times of microencapsulated anthocyanins at 4, 25 and 37 degrees C were determined as 12.16, 6.60 and 3.12months for freeze-dried microcapsules, and 16.50, 9.24 and 4.29 months for spray-driedmicrocapsules, respectively.
- MakaleYalnız künye2018The effect of quench-aging on the mechanical properties of Zn-27Al-1Cu alloy
Aydin, Murat; Senaslan, Fatih
The ternary alloy Zn-27Al-1Cu was produced by permanent mold casting. As-cast alloy was aged for different periods after being subjected to solution treatment followed by water quenching. The microstructure, mechanical properties and fatigue behavior of as-cast and heat-treated alloy were then investigated. The quench-aging eliminated the as-cast dendritic structure and produced a uniform microstructure consisting of large grains combined with precipitates. The hardness and tensile strength generally increased, whereas the ductility slightly decreased with aging time. Under all conditions, the longest fatigue life was obtained from the alloy that had been aged for 0.5 h, while the alloy which had been aged for 10 h exhibited the shortest. The fatigue properties were found to be more dependent on impact toughness and elongation, rather than tensile strength.
- MakaleAçık Erişim2013Sequence Variant in the LPIN1 gene in Patients with Metabolic Syndrome
Kural, Birgul Vanizor; Deger, Orhan; Erem, Cihangir; Yücesan, Fulya Balaban; Barlak, Yasam; Turan, Ibrahim; Aliyazicioglu, Rezzan
Objective: Metabolic syndrome (MetS) is a complex disease characterized by insulin resistance, abdominal obesity, hyperglycemia, hypertension, hypertriglyceridemia and low HDL-cholesterol level. The aim of the study was to evaluate the sequence variations in the LPIN1 gene in MetS. This gene codes lipin-1 protein which functions as Mg-dependent phosphatidic phosphatase enzyme and transcriptional coactivator. Material and Methods: The study groups included 73 MetS (19 M/54 F) and 56 non-MetS (16 M/40 F). Sequence variation in exons 2, 4, 5 and 14 of the LPIN1 gene were investigated by DNA sequencing method. Results: c.696 G>C variant (p.S232S) in exon 5 was observed in only one women with MetS. But this variation is not important because of coding same amino acid. Conclusion: Any important sequence variant was not detected in exons 2, 4, 5 and 14 in the LPIN1 gene in MetS.
- MakaleYalnız künye2013A multistage variational iteration method for solution of delay differential equations
Gökdoǧan, Ahmet; Merdan, Mehmet; Ertürk, Vedat Suat
In this paper, the approximate solution of delay differential equations is obtained by a reliable algorithm based on an adaptation of the classical variational iteration method (VIM), which is called the multi-stage variational iteration method (MSVIM). Examples are carried out and numerical results with comparison to exact solutions, VIM and MATLAB dde23 solver are given. The comparison reveals that the MSVIM is a promising tool to solve delay differential equations.
- MakaleAçık Erişim2011Frequency optimization of laminated skewed open cylindrical shells
Topal, Umut; Uzman, Ümit
This paper deals with frequency optimization of symmetrically laminated skewed open cylindrical shells. The design objective is the maximization of the fundamental frequency and the design variable is the fiber orientations. The firstorder shear deformation theory (FSDT) is used for the finite element solution of the shells. The modified feasible direction (MFD) method is used for the optimization routine. For this purpose, a program based on FORTRAN is used. Finally, the numerical analysis is carried out to investigate the effect of skew angles, length to radius ratios, subtended angle and boundary conditions on, the optimal designs and the results are compared.
- DergiINTERNATIONAL JOURNAL OF MATERIALS RESEARCH