Determination of Antioxidant and Antimicrobial Properties of Lady's Mantle (Alchemilla ellenbergiana) Extracts

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In this study, different polarity solvent (hexane, ethyl acetate, ethanol and methanol) extracts of Alchemilla ellenbergiana (Lady's Mantle), which used in folk medicine plant in Gümüşhane region, were investigated in terms of total phenolic contents, antioxidant and antimicrobial activity. Total phenolic contents were measured by spectrophotometric metod as gallic acid equivalent and detect in the highest in ethanol and methanol extracts. Antioxidant activity of extracts were determined by ABTS [2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt] and DPPH (2,2-diphenyl-1-picrylhydrazyl) methods by spectrophotometric metod and calculated as trolox equivalent. Antimicrobial activity was tested against to pathogen microorganisms by disc diffusion method. As a result, it has been found that ethanol and methanol extracts of plant have high antioxidant and antimicrobial activity (p<0.05). Similarly, it has been found that antimicrobial activity of ethanol and methanol extracts higher than others

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dc.contributor.authorOzcan, Kadriye
dc.contributor.authorAcet, Tuba
dc.date.accessioned2026-10-22T10:45:20.917733525Z
dc.date.available2026-10-22T10:45:20.917733525Z
dc.date.issued2018
dc.description.abstractIn this study, different polarity solvent (hexane, ethyl acetate, ethanol and methanol) extracts of Alchemilla ellenbergiana (Lady's Mantle), which used in folk medicine plant in Gümüşhane region, were investigated in terms of total phenolic contents, antioxidant and antimicrobial activity. Total phenolic contents were measured by spectrophotometric metod as gallic acid equivalent and detect in the highest in ethanol and methanol extracts. Antioxidant activity of extracts were determined by ABTS [2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt] and DPPH (2,2-diphenyl-1-picrylhydrazyl) methods by spectrophotometric metod and calculated as trolox equivalent. Antimicrobial activity was tested against to pathogen microorganisms by disc diffusion method. As a result, it has been found that ethanol and methanol extracts of plant have high antioxidant and antimicrobial activity (p<0.05). Similarly, it has been found that antimicrobial activity of ethanol and methanol extracts higher than others
dc.identifier.eissn2146-538X
dc.identifier.endpage121
dc.identifier.issue1
dc.identifier.startpage113
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/gumushane/18475
dc.identifier.volume8
dc.language.isotr
dc.relation.ispartofGümüşhane Üniversitesi Fen Bilimleri Dergisi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectKimya, Tıbbi
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.titleDetermination of Antioxidant and Antimicrobial Properties of Lady's Mantle (Alchemilla ellenbergiana) Extracts
dc.typeArticle
rdl.citation.trdizin9
rdl.source.indexTRDIZIN