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- MakaleAçık Erişim2025Scopus SJRQ3The relationship between internet and smartphone addiction and body mass index: The mediating role of eating behaviors
Türkkan, Tuğba; Bülbül, Kenan; Yilmaz, Hacı Ömer; Meriç, Çağdaş Salih
This research was conducted determine the mediating role of eating habits in the effect of internet and smartphone addiction on body mass index. The study group consisted of 604 individuals aged between 18 and 45 years (Mean(Age) = 21.07, SD = 3.00). Data were collected using Young Internet Addiction Scale, Smartphone Addiction Scale Short Form and Three-Factor Eating Questionnaire. Findings show positive correlations between internet addiction and smartphone addiction with uncontrolled eating, cognitive restraint and emotional eating behavior. Internet and smartphone addiction were determined to positively predict emotional eating behavior, uncontrolled eating behavior and cognitive restraint. The direct effect and total effect of internet addiction on body mass index were insignificant. However results show that both smartphone and internet use by individuals affect body mass index mediated by eating behavior. This is the first study showing that smartphone and internet use both affected body mass index mediated by eating behavior. Research results emphasise the threat of addiction on physical health and suggest that educational and cognitive dietary interventions can contribute to healthy eating habits. Additionally, considering the internet may be used as an emotion regulation strategy, intervention programs may focus on developing emotion regulation skills aiming to develop coping ability for negative emotions to reduce emotional or uncontrolled eating.
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İncele - MakaleAçık Erişim2026Scopus SJRQ1Thermochemical Activation of Lightweight Slag–Perlite Alkali-Activated Slag (AAS): Overcoming Aggregate Brittleness and Sulfate Degradation
Eker, Hasan; Demir Şahin, Demet
The successful realization of a circular economy in the cement industry, coupled with a substantial reduction in carbon emissions, relies on the development of sustainable alternative binder systems. This study investigated the physicomechanical performance and sulfate resistance of composites produced by alkali activation of natural perlite and blast furnace slag. The aim of the research was to improve mechanical properties under low- and medium-alkalinity conditions (5–10 M NaOH). The samples were cured at an ambient temperature of 20 °C and then treated with heat at 60 °C. These samples were then mechanically processed and subjected to five soak–dry cycles in 5% and 10% Na2SO4 solutions. The results showed that heat treatment resulted in the formation of a dense C-A-S-H gel, increasing compressive strength approximately eightfold, from 11.64 MPa to 92 MPa. However, perlite’s porous and brittle structure limits its flexural strength to 0.27 MPa; this value is insufficient for structural applications. Under severe sulfate attack (10% Na2SO4), samples cured at ambient temperature showed a 12% mass increase in the first cycle due to solution infiltration into capillary voids. As a consequence of extensive ettringite and gypsum formation, the specimens experienced severe deterioration, resulting in a complete loss of mechanical integrity and a residual compressive strength of 0 MPa. In contrast, heat-treated samples showed limited ion diffusion due to a denser matrix and an improved aggregate interface transition zone, resulting in a 2.6% mass increase and a residual compressive strength of 5.17 MPa. Consequently, the obtained findings indicate that thermally treated alkali-activated slag–perlite composites exhibit high resistance against sodium sulfate attack and may have potential for use in specific industrial environments with high sulfate concentrations. However, the performance of these materials under more complex aggressive conditions, such as mining environments involving magnesium sulfate exposure and acidic drainage waters, should be further validated through future studies.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2019Scopus SJRQ4Mapping Istanbul quarry mining region using Landsat 8 OLI&TIRS data
Balcik, Filiz Bektas; Topaloglu, Raziye Hale; Goksel, Cigdem
Open mining operations have brought number of environmental challenges, which may result in soil erosion, dust, noise, water pollution, and severe impacts on biodiversity. Determination of the mining activities and its surrounding environment is a major issue in sustainable resource management. Many remote sensing indices have been developed and widely applied as an effective tool to determine different land surface types. The main objective of this study was to determine quarry mines and its surroundings land use and land cover (LULC) categories in the selected study area of Istanbul using different remote sensing indices including Tasseled Cap Transformation (Brightness, Greenness and Wetness) and Normalized Difference Bareness Index (NDBals). In this study, an open mining area in the northern Black Sea coastal part of Istanbul was selected as study area. Freely available Landsat 8 OLI & TIRs image was used to determine quarries and land cover/ land use categories in the concerned area. By using original bands of Landsat 8 OLI, TCT components and NDBal, three different data sets were created. Each image was then separately subjected to support vector machine classification and processed to identify and quantify LULC categories. The accuracy of classification results were evaluated in a comparitive manner using error matrix. Data set C had the highest overall accuracy and Kappa statistics that were calculated as 83.00 and 0.80, respectively.
AtıfScopus1İncele - MakaleAçık Erişim2026Scopus SJRQ4Impact of cooking methods on PAH formation in traditional Akçaabat meatballs
Bostan, Sinan; Gül, Abdulkadir; Karpuz, Ömer; Baltaci, Cemalettin; Yılmaz, Fırat
Akçaabat meatballs, a traditional and commercially important Turkish meat product, are widely consumed and typically prepared using high-temperature cooking methods that may promote the formation of polycyclic aromatic hydrocarbons (PAHs). This study aimed to evaluate the effect of different cooking techniques, including pan cooking without added oil (dry pan cooking), electric grilling, oven baking, charcoal barbecue, and hazelnut shell charcoal barbecue, on PAH formation in Akçaabat meatballs. Samples obtained from eight different producers were analyzed for selected chemical properties and PAH contents using HPLC-FLD. While basic compositional characteristics varied among samples, the most significant differences were observed in PAH levels depending on the cooking method. The sum of four priority PAHs (∑PAH4) ranged between 7.70 and 112.38 µg/kg across all treatment s. Among the cooking methods, barbecue applications (charcoal and hazelnut shell charcoal) resulted in the highest PAH levels, frequently exceeding regulatory limits. In contrast, electric grilling produced the lowest PAH concentrations and showed the highest compliance with food safety standards. These findings demonstrate that cooking method plays a critical role in PAH formation and highlight the importance of selecting appropriate cooking techniques to minimize health risks. In this context, electric grilling can be considered a safer alternative, whereas traditional charcoal-based cooking methods may pose a significant risk in terms of PAH exposure.
- MakaleAçık Erişim2026Scopus SJRQ1Isolation and Preliminary In Vitro Characterization of a Honey-Derived Bacillus licheniformis Isolate
Usta, Mehtap; Zengin, Kübra; Kara, Yakup; Nalçacıoğlu, Remziye; Demirbağ, Zihni; Yıldız, Oktay; Kolaylı, Sevgi
Background/Objectives: Despite its hostile physicochemical environment characterized by high osmotic pressure, acidic pH, and low water activity, honey serves as a unique ecological niche for resilient microorganisms. This study aimed to recover bacterial isolates from honeys of different botanical origins and to characterize the probiotic-associated properties of a honey-derived Bacillus licheniformis isolate. Methods: A total of 20 bacterial isolates were recovered from four honey samples, including two blossoms and two honeydew honeys. 16S rRNA gene sequence analysis showed that the recovered isolates had taxonomic assignments consistent with Bacillus licheniformis. Because 16S rRNA sequencing does not provide sufficient resolution to establish strain-level diversity or clonality, one isolate, designated Blhoney, was selected for subsequent molecular and functional characterization. Results: In vitro assays revealed that Blhoney exhibits robust tolerance to simulated gastrointestinal stress, including extreme acidity (pH 1–3), bile salts (0.3–1%), pepsin, and pancreatin, maintaining viability for up to 24 h. Phenotypic antimicrobial testing demonstrated measurable inhibition zones for erythromycin, kanamycin, chloramphenicol, ampicillin, tetracycline, gentamicin, streptomycin, and spectinomycin, whereas no measurable inhibition zones were observed for penicillin G, rifampicin, ciprofloxacin, or ceftazidime. However, MIC determination and standardized breakpoint interpretation were not performed; therefore, these findings were interpreted solely as preliminary phenotypic inhibition-zone observations. Although the isolate did not display direct antagonistic activity against the tested bacterial pathogens under experimental conditions, its persistence under the tested gastrointestinal stress conditions supports further investigation of its probiotic-associated characteristics. Conclusions: Overall, these findings indicate that the honey-derived Blhoney isolate exhibits preliminary probiotic-associated characteristics under the tested in vitro conditions. However, further strain-level genomic and safety characterization is required before its potential probiotic application can be established.
- MakaleYalnız künye2026Scopus SJRQ2Natural (226Ra, 232Th, 40K) and artificial (137Cs) radioactivity assessment of Kırkpavli and Hazine Cave ore deposits, Gümüşhane (Türkiye): Radiological risk and material utilization perspective
Vural, Alaaddin; Kaya, Ali
Environmental radioactivity is a critical factor for both ecological and human health risk assessment, particularly in mining regions with ongoing or historical settlement activities. This study evaluates natural and artificial radionuclide concentrations in soils from the Kırkpavli (KP) and Hazine Cave (HM) mining areas in Gümüşhane, northeastern Türkiye. Gamma spectrometry analyses were performed to measure 232Th, 226Ra, 40K, and 137Cs, and radiological risk indicators—including absorbed dose rates, annual effective dose, radium equivalent activity, hazard indices (Hex and Hin), Excess Lifetime Cancer Risk (ECLR), Activity Utilization Index (AUI), radon-related alpha index, and natural radioactivity-driven heat production (RHP)—were assessed. Results: showed spatial variability linked to lithology, with the HM site exhibiting elevated radionuclide levels in basalt-dominated units, while KP soils showed moderate values in sedimentary formations. Most radiological parameters remained below international safety limits; however, specific sampling points, particularly HM-2, exceeded thresholds, indicating potential health risks if the soils are used for local settlement, building materials, or domestic purposes. RHP analysis further identified areas of intense hydrothermal alteration correlating with higher natural radioactivity. Comparisons with international soils and rocks confirmed that the activity concentrations at both sites are comparable to or exceed global averages. These findings highlight the necessity of ongoing monitoring of naturally occurring radioactive materials (NORM) in inhabited mining regions and provide essential data for ensuring environmental safety, sustainable land and material use, and public health protection.
- MakaleAçık Erişim2025Scopus SJRQ1Preserving local gastronomy as cultural heritage in Türkiye: a qualitative study on sustainable valorization of fethiye wedding foods
Özdemir, Özcan; Akyürek, Suat; Bahar, Ozan
Food and beverages are integral elements of cultural heritage, reflecting societies’ histories, identities, and values. However, globalization and changing lifestyles have diminished the diversity of traditional cuisines, posing a threat to their preservation. Showcasing these culinary traditions, particularly in tourism destinations, can contribute to raising awareness and safeguarding cultural heritage. This study investigates the traditional wedding foods and table customs of Fethiye, which are at risk of being forgotten, and explores their potential as tourism assets. A qualitative research design was applied, combining semi-structured interviews with local experts and direct observations at wedding ceremonies. The findings reveal that Fethiye’s gastronomic traditions hold significant potential for sustainable tourism development. The study concludes by offering practical recommendations and highlighting the importance of community participation in preserving culinary heritage.
AtıfOpenAlex3İncele - MakaleYalnız künye2026Scopus SJRQ1Impact of soil-structure interaction on earthquake response of high-rise steel frames equipped with TMD and FTMD optimized through cloud drift optimization
Alibabaei Shahraki, Mohammad; Araz, Onur; Ahmadi, Hossein
Vibration control of tall buildings under various seismic and foundation conditions remains a critical issue in earthquake engineering. This paper investigates the performance of Tuned Mass Damper (TMD) and Friction Tuned Mass Damper (FTMD) systems in reducing the seismic response of fixed-base and Soil-Structure Interaction (SSI) analyses of 20- and 40-storey steel moment-resisting frames. The current study uses the OpenSees software and the Cloud Drift Optimization (CDO) technique, aiming at minimizing the normalized H 2 -norm of the roof displacement. The performance of the seismic control is investigated by performing nonlinear dynamics analyses with the help of a set of 14 records, of which 7 records are far-field and the remaining ones are near-field records. Results show that both TMD and FTMD are effective in decreasing roof displacement on 20- and 40-story buildings subjected to fixed-base and SSI excitations. More precisely, results for the average reduction in roof displacement are 33.4% and 27% when FTMD is subjected to SSI loading, while those values were 10.7% and 16.5% when TMD was subjected to SSI loading in the case of 20- and 40-story buildings, respectively. Results are based on multiple variables including base shear, kinetic energy, and damping energy. The results demonstrate that the FTMD system provides superior seismic response reduction compared to the conventional TMD.
AtıfScopus5WoS5OpenAlex2İncele - MakaleAçık Erişim2018Scopus SJRQ1A study of Bos taurus muscle specific enolase; biochemical characterization, homology modelling and investigation of molecular interaction using molecular docking and dynamics simulations
Sariyer, Emrah; Yakarsonmez, Sinem; Danis, Ozkan; Turgut-Balik, Dilek
Tropical theileriosis caused by Theileria annulata obligate parasite that infect ruminant animals, including Bos taurus. The disease results massive economic losses in livestock production worldwide. Here we describe cloning, expression and both biochemical and structural characterization of beta enolase from Bos taurus in vitro and in silico. The interconversion of 2‑phosphoglycerate to phosphoenolpyruvate was catalyzed by enolase is a metalloenzyme in glycolytic pathway and gluconeogenesis. Enolase from Bos taurus was cloned, expressed and the protein was purified at 95% purity using cobalt column by affinity chromatography. The optimum enzymatic activity was calculated at pH 6.5. For the first time in the literature, the kinetic parameters of the enzyme, Vmax and Km, were measured as 0.1141 mM/min and 0.514 mM, respectively. Besides, Bos taurus enolase 3-dimensional structure was built by homology modelling to be used in silico analyses. The interactions of the enzyme-substrate complex were elucidated by molecular dynamics simulations for 100 ns. These interactions were found to be the same as experimentally determined interactions in yeast. These results would enable further structure based drug design studies with the biochemical characterization of the host organism Bos taurus enolase enzyme in vitro and the elucidation of behavior of enzyme-substrate complex in silico.
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İncele - MakaleYalnız künye2015Scopus SJRQ1A review for genesis of continental arc magmas: U, Th, K and radiogenic heat production data from the Gümüşhane Pluton in the Eastern Pontides (NE Türkiye)
Maden, Nafiz; Akaryali, Enver
In this study, in situ radioelemental (238U, 232Th and 40K) measurements and heat production rate evaluation have been conducted at 132 sites in the Gümüşhane Pluton of the Eastern Pontides Orogenic Belt (EPOG) of Northern Türkiye. The average K, U and Th values for granites are 4.35±0.71%, 5.85±2.74ppm, 22.13±5.55ppm, respectively; microgranites 4.33±1.37%, 7.12±2.23ppm, 24.11±9.59ppm; metagranite 3.93±0.68%, 6.24±2.75ppm, 12.87±3.92ppm; andesite/basalt 1.75±0.74%, 3.22±1.07ppm, 9.01±5.14ppm. Based on the abundances of K, U and Th, the radiogenic heat production (RHP) values, which is a reflection of the geological rock types, are estimated as 3.52±1.03μWm-3, 3.86±1.31μWm-3, 2.93±0.89μWm-3, and 1.68±0.63μWm-3 for granites, microgranites, metagranites and andesite/basalt, respectively. The average heat production value for the study area is estimated as 2.83±1.39μWm-3, which is closer to the upper continental crustal value; contrary to the highest heat production value of granitic basement and the lowest heat production values of the sedimentary rocks. The study region is depicted with very high level of Th/U value ranging from 0.11 to 23.19 with mean value of 3.53 ± 2.5, which is comparatively close to the upper continental crustal estimate of 3.8. The numerical results verify that mantle-derived magmas are subjected to contamination with both middle and lower crustal material constituted by fragments of southerly dipping subduction of Tethys Ocean during the late Mesozoic-Cenozoic.
AtıfScopus19WoS18OpenAlex20İncele - MakaleYalnız künye2026Scopus SJRQ1Effects of an Immersive Virtual Reality-Based Exercise-Rest on Mobilization in Knee Surgery Patients: A Single-Blind, Randomized Controlled Trial
Aydin, Aydanur; Menekşeoğlu, Ahmet Kıvanç; Dilaver, İrem; Taş, Süleyman Kasım
Purpose This study aimed to evaluate the impact of immersive virtual reality (IVR) interventions on enhancing mobilization in patients undergoing total knee arthroplasty. Design A randomized, single-blinded, two-arm, parallel-group controlled trial. Methods A randomized controlled trial was conducted on 30 patients who underwent total knee arthroplasty for the first time. Participants were divided into two groups: the intervention and control groups. The primary outcome, mobilization distance, was measured at the first postoperative mobilization using validated scales. Before mobilization, patients in the intervention group experienced a simulated walk through a tranquil forest accompanied by birdsong and meditation music via IVR goggles. Results All surgeries were performed by the same surgeon, and postoperative medical care was standardized across both groups. The intervention group demonstrated significantly greater mobilization distances and shorter initial walking times than the control group. Moreover, patients in the intervention group reported reduced postmobilization pain and expressed high satisfaction with the IVR experience. Conclusions The findings indicate that patients who experienced IVR intervention exhibited reduced postmobilization pain, increased mobilization distance, and higher satisfaction. This innovative technique has the potential to serve as a practical solution to enhance clinical improvement in various healthcare settings. Clinical Implications This study demonstrated the effectiveness of IVR-assisted mobilization in enhancing walking distance among patients undergoing knee surgery. The use of IVR presents an innovative and engaging approach to support postoperative mobilization in this patient population. Further research in this area may contribute to the development of more comprehensive and effective IVR interventions.
- MakaleAçık Erişim2026Scopus SJRQ1Serum and hepatic lipid fractions and total protein status of laying hens supplemented with tarragon (Artemisia dracunculus L.) under different stocking densities
Kaya, Hacer; Karaalp, Musa; Kaynar, Özgür; Elmastaş, Mahfuz
High stocking density can induce metabolic disturbances in laying hens, particularly in lipid metabolism. This study evaluated the effects of dietary tarragon (Artemisia dracunculus L.) supplementation on serum and hepatic total protein and lipid parameters in laying hens reared under different stocking densities. A total of 192 50-week-old Lohmann Brown laying hens were assigned to a 2 × 4 factorial arrangement with two stocking densities, 5 or 7 hens per cage, and four dietary tarragon treatments providing 0, 1, 5, or 10 mmol/kg feed of tarragon-derived additional antioxidant activity for 8 weeks. Serum total protein concentration was not affected by stocking density but increased with tarragon supplementation, rising from 7.5 to 8.3 g/dL. Liver total protein concentration remained unchanged. SDS-PAGE analysis of pooled treatment-group samples identified 24 serum and 39 hepatic protein bands. High stocking density altered the serum lipid profile by increasing cholesteryl ester, free fatty acid, and acylglycerol proportions, as well as total cholesterol and triacylglycerol concentrations, while decreasing triacylglycerol and phospholipid proportions. Tarragon supplementation increased serum cholesteryl ester and phospholipid proportions and reduced serum triacylglycerol and free fatty acid proportions, together with lower total cholesterol and triacylglycerol concentrations. In the liver, high stocking density increased cholesteryl ester and free cholesterol proportions and triacylglycerol concentration, whereas it decreased triacylglycerol and phospholipid proportions and total cholesterol concentration. Tarragon supplementation increased hepatic cholesteryl ester, free cholesterol, and phospholipid proportions and reduced hepatic triacylglycerol proportion and concentration. Significant stocking density × tarragon-derived additional antioxidant activity interactions were observed for serum free fatty acid and hepatic free fatty acid and free cholesterol. Overall, stocking density had a stronger effect on lipid metabolism than on total protein status.
- Derleme MakaleYalnız künye2026Scopus SJRQ2A systematic review of studies evaluating immersive virtual reality applications to support nursing education for nursing students
Aydin, Aydanur; Güler, Sevil; Bulut, Hülya
Objectives: Virtual reality (VR)-based interventions are widely used in education. However, it is necessary to systematically examine the outcomes of immersive virtual reality (IVR) applications in nursing education, clarifying their impact on knowledge, skills, and attitudes among nursing students. Methods: This review utilized the methodological framework of the Joanna Briggs Institute. A search was conducted of the Ovid MEDLINE, PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Web of Science, and Scopus databases for the period from 2013 to 2023. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol informed the review and screening of the literature. The articles were assessed for eligibility via first screening by abstract review, followed by a full-text review. The first two authors reviewed the articles, assessing qualification for inclusion and evaluating the content. Data from eligible articles were analyzed and synthesized to answer the research question. Results: Of the initial 667 articles, 11 articles met the inclusion criteria for final analysis. The findings indicate that IVR applications in clinical practice positively impact nursing students, as IVR provides effective results in increasing their knowledge. Nursing educators should avoid comparing the results of students’ IVR practice with classical clinical practice. Nursing students should continue to engage in clinical practice, as it remains an essential aspect of their education. While technological applications such as IVR may be useful, they should not be used as a substitute for clinical practice. This review highlights the reported outcomes and benefits of clinical teaching methods in nursing. Conclusion: A limited number of articles were found that evaluated the education of nursing students in IVR applications. The analyzed articles found that nurse educators experienced meaningful knowledge exchange with students after IVR implementation. Further research is needed to identify effective outcomes in clinical education. It is essential to advance science to transform clinical education and use it more consciously to teach practical thinking and decision-making about patient care.
- MakaleAçık Erişim2026Scopus SJRQ1Psychometric properties of the Turkish version of the VARK learning style inventory for athletes
Türker, Üstün; Somoğlu, Mustafa Barış; Koç, Mustafa; Bostancı, Özgür
Background: Understanding how athletes learn and recognizing their learning preferences are important cognitive and sensory components that may support effective instructional planning in sport settings. This study aimed to adapt the VARK Learning Style Inventory for Athletes (Visual, Aural, Read/Write, and Kinesthetic modalities) into Turkish and to evaluate its psychometric properties. Methods: A total of 854 licensed athletes from individual and team sports in Türkiye participated in the study. The Turkish version of the VARK Learning Style Inventory for Athletes was administered using a paper-based format. Data were analyzed using IBM SPSS Statistics (v26) and LISREL (v8.80). Construct validity was examined using a Multitrait–Multimethod Confirmatory Factor Analysis (MTMM-CFA) approach with a correlated trait–correlated uniqueness (CTCU) specification, while reliability was assessed using internal consistency and test–retest procedures. Results: The MTMM-CFA supported the four-factor structure of the inventory, indicating an acceptable model fit and strong associations among the learning style dimensions, consistent with a multimodal learning preference profile. Internal consistency analyses yielded Kuder–Richardson 20 (KR-20) coefficients ranging from 0.574 to 0.623 across subscales, reflecting moderate reliability. Conclusions: The findings suggest that the Turkish version of the VARK Learning Style Inventory for Athletes demonstrates acceptable psychometric properties, with evidence of construct validity and moderate internal consistency. While the results support its use for assessing learning preferences among Turkish athletes, further research across different sport disciplines and age groups is recommended to strengthen there liability evidence and practical applicability. Overall, the study contributes to measurement practices in sport and exercise sciences by providing a culturally adapted instrument for examining athletes’ learning preferences.
AtıfOpenAlex1İncele - Kitap BölümüYalnız künye2026The Influence of the Anglo-American Alliance on Shaping Iranian Foreign Policy
Topal, Coşkun; Bülbül, Berke; Maden, Nafiz
Since the 19thcentury, Britishoilinterests and geopoliticalbalancing against Russia positionedIran as a criticalbuffer zone. The Anglo-American-backed1953Operation Ajax generateda traumatic collective memory that formedthe ideological foundation of Iranian foreign policy after the 1979 Revolution. In the post-revolutionary era, Tehran transitioned into a security-oriented state, adopting severe anti-imperialist rhetoric against US and UK. Confronting US economic sanctions, “rogue state” labeling, andnuclearcounter-pressures, Iranbuiltasymmetricresistancemechanisms through the “Shia Crescent” and regional proxy networks. Meanwhile, diplomatic crises with UK, such as the Salman Rushdie affair, further hardened this defensive stance. This study examines how Iran transforms Anglo-American threat perceptions into a source of regime legitimacy and strategic autonomy.
- MakaleYalnız künye2026Scopus SJRQ1Effects of sunlight ripening process on the biological activities of persimmon (Diospyros kaki L.) peel and pulp extracts
Kardil, Uğur; Akar, Zeynep; Düzgün, Azer Özad
The aim of the study was to evaluate the biological properties of the peel and pulp extracts of persimmons, with consideration of the impact of different ripening conditions (B: on-branch ripened and S: sunlight ripened). The data demonstrated that the sunlight ripened persimmon peel (S. peel) extract exhibited a higher total phenolic and flavonoid content, with 157 and 7.3 µg/mL GAE respectively. The S. peel extract exhibited the highest antioxidant activity, exhibiting 1.1578 mg/mL IC50, 54.095 and 0.0262 µM Trolox equivalent (TE)/g fresh weight (FW), as determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH•) radical scavenging assay, ferric reducing antioxidant power (FRAP) and cupric reducing antioxidant capacity (CUPRAC) respectively. LC-MS/MS analysis revealed that the peel and pulp phenolic composition of persimmon ripening process different conditions changed. The activity of protocatechuic, chlorogenic, caffeic and ferulic acids identified in persimmon extracts was determined by HPLC-DAD-FRAP assay. ICP-OES analysis revealed that potassium exhibited the highest mineral content of persimmon, with values ranging from 575.680 to 2031.360 mg/kg. The S. peel extract was more inhibitory activity against bovine carbonic anhydrase (BCA) and α-glucosidase then other extracts. Moreover, the S. peel extract was found to demonstrate the highest level of antibiofilm activity, reducing the strong biofilm formation capacity of the A. baumannii isolate to negative, both qualitatively and quantitatively. The study suggests that the ripening of persimmon fruit in sunlight may increase biological activity and may be useful in the prevention and treatment of diseases associated with oxidative damage, diabetes and bacterial infections.
- MakaleYalnız künye2026Scopus SJRQ2Sustainable Nutrition Behaviors and Physical Activity Attitudes Among College Students: A Cross-Sectional Study
Kurtbeyoglu, Emine; Kaya, Aleyna
Objective: This study aimed to examine sustainable nutrition behaviors and attitudes toward physical activity among college students. Design: A cross-sectional study. Setting: College setting. Participants: The study included 303 college students (171 female, 132 male). Main Outcome Measure: Sustainable nutrition behaviors were assessed using the Behaviors Scale Towards Sustainable Nutrition, whereas beliefs and attitudes related to physical activity were measured using the Exercise Health Belief Model Scale. Anthropometric measurements, including body weight and waist circumference, were obtained by researchers. Analysis: Pearson and Spearman correlation analyses, as appropriate, and multiple linear regression analyses were conducted. Results: Sustainable nutrition behavior scale total scores were positively correlated with exercise Health Belief Model scores (r = 0.444, P < 0.001) and negatively correlated with body mass index (r = −0.142, P = 0.01) and waist circumference (r = −0.169, P = 0.003). After adjusting for sex, academic level, and income level, sustainable nutrition behaviors remained significantly associated with attitudes toward physical activity (β = 0.400, P < 0.001), explaining 22.6% of the variance (R² = 0.226). Conclusions and Implications: Students with more positive attitudes toward physical activity are more likely to engage in sustainable nutrition behaviors. Integrated health promotion strategies addressing both physical activity and sustainable nutrition may support healthier and more sustainable lifestyles among college students.
- MakaleAçık Erişim2025Scopus SJRQ3Effects of Varying Ratios of Hawthorn Fruit Extract on Nesfatin-1, GLP-1 and cTnI Response in Streptozotocin-induced Diabetic Rats
Özcan, G. Böyük; Kaya, H.
Background: The aim of this study was to investigate the ef fects of Hawthorn (Crataegus oxyacantha) Fruit Extract on the response of nesfatin-1, Glucagon-like peptide 1 (GLP-1) and cardiac troponin I (cTnI) in STZ-induced diabetic rats. Methods: This study utilized 64 adult male Wistar albino rats, aged 8-10 weeks and weighing an average of 195-215 g. Eight groups were randomly selected, each comprising eight rats designated as Control (C), H100, H200, H300; Diabetes Control (DC), DH100, DH200, DH300. Blood samples were collected from the tail vein (vena caudalis) of all individuals on days 0 and 21 of the research. The serum levels of Nesfatin-1, GLP-1 and cTnI were quantified and assessed using the ELISA technique. Result: In diabetic groups, the increase in serum mean nesfatin-1 and cTnI levels was most pronounced in DC groups, while the most significant decrease due to increased HFE supplementation was observed in DR200 groups (p<0.01); whereas in diabetic groups, the decrease in serum mean GLP-1 levels was observed in DC group, while the most significant increase due to increased HFE supplementation was detected in DG200 group. As a result, it was concluded that 200 mg/kg RPE administration to healthy and di abetic rats di d not cause any side eff ects. It was concluded that HFE, which has an anti-diabetic eff ect by regulating the inflammatory response that plays a role in the development of diabetes, decreasing nesfatin-1 levels and increasing GLP-1 levels, may be useful in supporting the impaired pancreatic beta cell function that occurs in diabetes.
AtıfScopus1WoS1İncele - MakaleYalnız künye2026Scopus SJRQ3Nicotinamide complexes of metal(II) furan-2-carboxylates: synthesis, determination of crystal structures, Hirshfeld surface analysis, and in vitro and in silico evaluation of inhibitory properties on CA I, CA II, AChE, BChE, and GR enzymes
Nar, Merve; Senturk, Murat; Kaya, Afşin Ahmet; Öztürkkan, Füreya Elif; Kaya, Elif Çelenk; Şahin, Ertan
In this study, nicotinamide complexes of Cu2⁺, Co2⁺, and Zn2⁺ furan-2-carboxylates were synthesized, and the crystal structures of the complexes were characterized by single crystal X-ray diffraction. The chemical composition and functional groups of the complexes were confirmed using elemental analysis, Fourier transform infrared spectroscopy (FT-IR), ultraviolet–visible region (UV–Vis) spectroscopy, and mass spectrometry (MS). Hirshfeld surface analysis detailed the intermolecular interactions present in the crystal structures of the complexes. The complexes feature a central six-coordinate ion (Cu2⁺, Co2⁺, or Zn2⁺) located on an inversion center, which is bonded to two N atoms from nicotinamide and four O atoms from water molecules. There is a furan 2-carboxylate anion that is not coordinated with metal atoms but links to complex structures via hydrogen bonds. Within the scope of biochemical studies, the inhibitory effects of the synthesized complexes on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase I and II (hCA I, hCA II), and glutathione reductase (GR) enzymes were investigated by spectrophotometric methods. It was determined that the complexes, especially Complex 2, exhibited strong enzyme inhibition properties. Molecular docking analyses revealed the binding tendencies and binding energies of the complexes to the active sites of the enzymes. Complex 2 has a high binding affinity with AChE, BChE, hCA I, hCA II, and GR enzymes, and these bindings were supported by hydrogen bonds and π-π interactions. ADMET predictions showed that the complexes have toxicologically safe profiles despite their pharmacokinetic limitations, such as low gastrointestinal absorption and inability to cross the blood–brain barrier. It was determined that the risks of hepatotoxicity, carcinogenicity, immunotoxicity, and mutagenicity were low. As a result, these metal complexes are evaluated as potential therapeutic agents in the treatment of diseases such as Alzheimer’s disease, glaucoma, epilepsy, malaria, and cancer. The data obtained in this study emphasize the biological activities and pharmacological potential of the complexes, and it is recommended that they be supported by future in vivo studies.
AtıfScopus4WoS4OpenAlex3İncele - MakaleAçık Erişim2026Scopus SJRQ1The mediating effect of self-compassion and cognitive emotion regulation on the relationship between tolerance and social appearance anxiety in adolescents
Bingöl, Orhan; Çelebi, Gülin Yazıcı; Kaya, Feridun
The aim of this study is to examine the effect of tolerance on social appearance anxiety and to test the roles of emotion regulation and self-compassion as mediating psychological mechanisms in this relationship. The sample of the study consists of 647 adolescent individuals living in Turkey. The Personal Information Form, Cognitive Emotion Regulation Questionnaire, Tolerance Scale, Self-Compassion Scale – Short Form, and Social Appearance Anxiety Scale were used in the study. Data were collected online using convenience sampling methods. Pearson correlation analysis was used to determine the relationships between the variables in the study, while regression-based mediation analysis (Process macro model 81) was used to test the mediation model examined in the study. Upon examining the findings, tolerance was positively correlated with self-compassion (r =.323, p <.001) and adaptive cognitive emotion regulation (r =.200, p <.001); while tolerance was negatively and statistically significantly related to maladaptive cognitive emotion regulation (r = -.250, p <.001) and social appearance anxiety (r = -.229, p <.001). Additionally, a positive correlation was found between self-compassion and adaptive cognitive emotion regulation (r =.358, p <.001); and negative and statistically significant relationships between self-compassion and maladaptive cognitive emotion regulation (r = -.576, p <.001) and social appearance anxiety (r = -.530, p <.001). Finally, a statistically significant negative relationship was found between social appearance anxiety and adaptive cognitive emotion regulation (r = -.219, p <.001); and a statistically significant positive relationship was found between social appearance anxiety and maladaptive cognitive emotion regulation (r =.484, p <.001). The mediation analysis, tested with 10,000 bootstrap samples at a 95% confidence interval, revealed that emotion regulation dimensions and self-compassion have a full mediating effect. The findings indicate that the tolerance factor reduces social appearance anxiety not only directly but also indirectly through emotion regulation and self-compassion. In line with these findings, it was concluded that individuals with high tolerance levels need to be supported not only through mindfulness programs but also through emotion regulation and self-compassion levels.
