Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2026Scopus SJRQ2
    Effects of transcutaneous auricular vagus nerve stimulation added to robotic rehabilitation in patients with ischemic stroke: a randomized clinical trial

    Kızıl, Ömer Dicle; Ural, İbrahim Halil; Hatık, Sefa Haktan; Özden, Ali Veysel; Aydın, Emine Büşra

    Background: This study aimed to investigate the effects of adding transcutaneous auricular vagus nerve stimulation (taVNS) to robotic rehabilitation on functional outcomes and neuromuscular activity in patients with ischemic stroke. Methods: This randomized controlled clinical trial employed a pre–post study design and was conducted in a hospital-based physiotherapy and rehabilitation clinic. A total of 40 patients with ischemic stroke, aged 18–65 years, were randomly assigned to either a robotic rehabilitation group (RRG) or a combined vagus nerve stimulation and robotic rehabilitation group (VRRG). Spasticity, walking speed, motor function, quality of life, muscle activity, and pain were assessed at baseline and after six weeks of treatment. Results: Primary outcome measures were walking speed, motor function assessed by the Fugl–Meyer Assessment, and pain intensity. Secondary outcomes included electrophysiological measurements (H-reflex and F-wave parameters) and quality of life. Within-group analyses showed significant improvements in all outcomes in the VRRG (p < 0.05), whereas all outcomes except pain improved significantly in the RRG (p < 0.05). Between-group comparisons demonstrated greater improvements in walking speed in the VRRG compared with the RRG (mean difference − 1.84 s, 95% CI − 3.7 to − 0.7; r = 0.43; p = 0.006) and greater pain reduction in the VRRG (mean difference − 1.55, 95% CI − 2.5 to − 0.1; r = 0.30; p = 0.048). In contrast, a greater reduction in the Hmax/Mmax amplitude ratio—an electrophysiological marker of spinal excitability—was observed in the RRG. Conclusion: The findings suggest that transcutaneous auricular vagus nerve stimulation combined with robotic rehabilitation may provide additional benefits in terms of walking speed and pain reduction in patients with ischemic stroke. Trial registration: The study was registered at ClinicalTrials.gov on April 19, 2024. (Identifier: NCT06381089).

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2026Scopus SJRQ2
    The effect of dance intervention on cognitive functions and quality of life in patients with Chronic Stroke: A single-blind, randomized controlled trial

    Cin, Aynur; Demirağ, Hatice; Hintistan, Sevilay

    Objective This study aimed to determine the effect of dance interventions on cognitive functions and quality of life in chronic stroke patients. Methods This research used a single-blind randomized controlled trial design involving 40 chronic stroke patients at X State Hospital who were divided into a dance intervention group and a control group. The dance group was given 60 min of sessions three times a week for 12 weeks under the guidance of a dance instructor. Both groups were pre-tested and post-tested using the Stroke Specific Quality of Life Scale (SS-QOL) and Montreal Cognitive Assessment (MoCA). Results The dance intervention group experienced significant improvements in SS-QOL sub-dimensions (energy activities, personality, social and family roles, thinking, language, mood) as well as MoCA scores compared to the control group which had deteriorated over time ( p < 0.001). Conclusion Dance interventions can significantly improve cognitive function and quality of life among chronic stroke patients. The study was registered on Clinical Trials (NCT06145503).

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2016Scopus SJRQ3
    Mean platelet volume is related with ischemic stroke in patients with sinus rhythm

    Özkan, Bugra; Arik, Osman Z.; Gözükara, Mehmet Y.; Sahin, Durmus Y.; Topal, Salih; Uysal, Onur K.; Elbasan, Zafer; Epçeliden, Tuncay; Çayil, Murat; Gür, Mustafa

    Stroke is the leading cause of disability worldwide. It is known that atrial fibrillation and left atrial enlargement contribute ischemic stroke, and mean platelet volume (MPV) increases in patients with ischemic stroke and atrial fibrillation. We aimed to determine whether higher MPV is associated with ischemic stroke in patients with sinus rhythm. We evaluated 74 patients in sinus rhythm and with ischemic stroke (Group 1) and 90 age-matched and sex-matched healthy individuals as control group (Group 2). After physical and echocardiographic examination, 24-48 h Holter monitoring and complete blood counts were studied. There were no statistically significant differences in age, sex rates, and comorbidities between groups. Left atrial diameter was higher in Group 1 than Group 2 (P=0.001), but both were in normal range. MPV was significantly higher in Group 1 (P<0.001) and was an independent determinant [odds ratio (OR): 1.840; P<0.001; 95% confidence interval (CI) 1.330-2.545] of ischemic stroke with left atrial (OR: 1.138; P=0.006; 95% CI 1.037-1.248). In conclusion, higher MPV is associated with acute ischemic stroke in patients with sinus rhythm and without heart failure or left atrial enlargement. MPV and left atrial diameter are independent predictors of ischemic stroke in this patient population. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
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