Sürdürülebilir Kalkınma Amaçları
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- MakaleAçık Erişim2024Scopus SJRQ3Physicochemical properties of chestnut honey vinegars enriched with pollen and propolis, and their analyses of mineral, colour, and antioxidant activity
Kobya, H.N.; Baltaci, C.; Karpuz, O.
Honey vinegar is little known in Turkey, while pollen- or propolis-added honey vinegar is yet to be found. Therefore, the objectives of the present work were to produce chestnut honey vinegar enriched with pollen and propolis, and to analyse their physicochemical compositions, mineral contents, colours, and antioxidant activities. Eleven different honey vinegars were produced using various methods. There were significant increases in the total antioxidant activity of both pollen- and propolis-enriched vinegars, with 73 and 56% increases, respectively, compared to plain honey vinegar, and these increases were more than twice that of grape vinegar. The ferric-reducing activity and phenolic content of vinegar enriched with propolis increased by 43 and 52%, respectively, compared to plain honey vinegar, and more than threefold compared to grape vinegar. Principal component analysis revealed a strong positive correlation among all antioxidant tests and the most significant components, including antioxidant capacity, total phenolic content, and total flavonoid content. The colour difference was determined as follows: 5 < total colour difference (∆E*ab). All vinegar samples exhibited highly variable physicochemical properties. High amounts of Na, K, Mg, and Ca were also detected. Vinegar samples containing pollen and propolis are suitable under the Turkish Food Codex legislation. The findings of the present work would encourage the production of honey vinegar enriched with pollen and propolis, as well as increase attention to honey vinegar.
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İncele - MakaleAçık Erişim2016Scopus SJRQ2Effect of Turkish pollen and propolis extracts on caspase-3 activity in myeloid cancer cell lines
Uçar, Meltem; Değer, Orhan; Gerigelmez, Asuman Yiğit; Cengiz, Sevil; Barlak, Yaşam; Ovalı, Ercüment
Purpose: To investigate the apoptosis-inducing capacity of dimethyl sulfoxide (DMSO) extracts of bee pollen and propolis in HL-60 Myeloid Cancer Cell Lines. Methods: DMSO extracts of pollen and propolis were incubated separately with HL-60 cells, and caspase-3 activity evaluated. In order to determine the cell cycle characteristics of HL-60 cells with and without extracts of pollen and propolis, the cells were analysed using flow cytometry. Results: The DMSO extract of propolis (0.5 mg/mL) increased apoptosis from undetectable levels to 60.1%, while maintaining cell viability. The DMSO extract of pollen (2 mg/ml) increased apoptosis from undetectable levels to 52.2% while decreasing cell viability by 62%. Caspase-3 activity in HL-60 cells incubated with DMSO extracts of pollen and propolis were 3.6-to 12-fold higher than in controls. Conclusion: Turkish pollen and propolis individually increase apoptosis and the activity of caspase-3 in HL-60 cells. This finding indicates that bee products may have beneficial effects in the treatment of cancer.
AtıfScopus12WoS10OpenAlex12İncele