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- MakaleAçık Erişim2020Knowing and Use Situations of Hemovigilance System in the Scope of Blood Transfusion Safety of Nurses: Rural Example
Demirag, Hatice; Hintistan, Sevilay
Objective: This study was carried out to determine the nurses' knowledge of the hemovigilance system and their use of it, within the scope of blood transfusion safety. Methods: The sample of this descriptive and cross-sectional study consisted of all nurses (n=65) working at Gumushane State Hospital. The data were collected with Structured Question Form Number, percentage, mean, Continuity Correction, Pearson Chi-Square and Fisher Exact tests were used to evaluate the data. Results: Of the nurses, 90.8% were women, the average age was 27.01 +/- 5.16 (20-48) years and 86.1% had undergraduate or higher education. Of the nurses, 84.6% knew that they were supervised by a hemovigilance nurse. Nurses (43.1%) who received training on the hemovigilance system had higher levels of knowing that each unit of blood taken from the donor follows the final destination (100.0%) than the nurses who did not receive training (p <0.05). The nurses who knew that they were supervised during transfusion related processes performed the following steps at a higher rate than those who did not know that they were inspected (p <0.05): Wearing gloves before the application (100.0%), using appropriate branches in children (87.3%), obtaining written consent before blood transfusion (100.0%), and completing the blood transfusion within a maximum of four hours (87.3%) were higher than nurses who did not know that they were supervised (p <0.05). Also; the majority of nurses (90.8%) were determined to use the current procedures for blood transfusions. Conclusion: In line with the findings of the study, it was stated that the nurses who were educated about the hemovigilance system and who knew that they were supervised by the hemovigilance nurse, had high hemovigilance system usage.
- MakaleAçık Erişim2019In vitro Antifungal Activities of Fluconazole, Camellia sinensis and Cydonia oblonga Leaf Extracts Against Candida Species Isolated from Blood Cultures
Hanci, Hayrunisa; Coskun, Mehmet Veysel; Uyanik, Muhammed Hamidullah; Sezen, Selma; Igan, Hakan
Objective: In this study we investigated in vitro antifungal activity of fluconazole, green tea (Camellia sinensis) and quince leaf (Cydonia oblonga) extracts in Candida strains isolated from blood cultures. Methods: Fifty Candida spp were included to study. Camellia sinensis and Cydonia oblonga leaves collected from Rize and Erzurum/Tortum regions were prepared as an extract. Then stock solutions of the extracts and fluconazole powder obtained from the manufacturer were prepared for use in the Broth Microdilution (BMD) method according to Clinical and Laboratory Standards Institute (CLSI) M27 A3 recommendation. Fluconazole minimum inhibitory concentration (MIC) values obtained from BMD method were evaluated according to CLSI M27 A4 break points. MIC values obtained for Camellia sinensis and Cydonia oblonga were interpreted according to fluconazole break points since there is no break points in the literature. Results: Of the 50 Candida spp. included in the study, 37 (74%) were C. albicans while 13 (26%) were non-albicans species. The most common isolated non-albicans species was C. parapsilosis (14%). For all tested Candida strains MIC 50 and MIC 90 values for fluconazole were found to be 0.125 mu g/mL- 0.25 mu g/mL while they were determined as 0.125 mu g/mL-64 mu g/mL and 0.125 mu g/mL-0.125 mu g/mL for green tea and quince leaves, respectively. Conclusion: According to the low MIC values, it is seen that green tea and quince leaf are in vitro effective against Candida species. However, further extensive in vitro and in vivo studies should be done on the possibility that green tea and quince leaf can be used alternatively in the treatment of invasive Candida infections.
- DergiBEZMIALEM SCIENCE