Sürdürülebilir Kalkınma Amaçları

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• MakaleYalnız künye2026/r/gumushane/13465
  Nicotinamide complexes of metal(II) furan-2-carboxylates: synthesis, determination of crystal structures, Hirshfeld surface analysis, and in vitro and in silico evaluation of inhibitory properties on CA I, CA II, AChE, BChE, and GR enzymes

  Nar, Merve; Senturk, Murat; Kaya, Afşin Ahmet; Öztürkkan, Füreya Elif; Kaya, Elif Çelenk; Şahin, Ertan

  In this study, nicotinamide complexes of Cu2⁺, Co2⁺, and Zn2⁺ furan-2-carboxylates were synthesized, and the crystal structures of the complexes were characterized by single crystal X-ray diffraction. The chemical composition and functional groups of the complexes were confirmed using elemental analysis, Fourier transform infrared spectroscopy (FT-IR), ultraviolet–visible region (UV–Vis) spectroscopy, and mass spectrometry (MS). Hirshfeld surface analysis detailed the intermolecular interactions present in the crystal structures of the complexes. The complexes feature a central six-coordinate ion (Cu2⁺, Co2⁺, or Zn2⁺) located on an inversion center, which is bonded to two N atoms from nicotinamide and four O atoms from water molecules. There is a furan 2-carboxylate anion that is not coordinated with metal atoms but links to complex structures via hydrogen bonds. Within the scope of biochemical studies, the inhibitory effects of the synthesized complexes on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase I and II (hCA I, hCA II), and glutathione reductase (GR) enzymes were investigated by spectrophotometric methods. It was determined that the complexes, especially Complex 2, exhibited strong enzyme inhibition properties. Molecular docking analyses revealed the binding tendencies and binding energies of the complexes to the active sites of the enzymes. Complex 2 has a high binding affinity with AChE, BChE, hCA I, hCA II, and GR enzymes, and these bindings were supported by hydrogen bonds and π-π interactions. ADMET predictions showed that the complexes have toxicologically safe profiles despite their pharmacokinetic limitations, such as low gastrointestinal absorption and inability to cross the blood–brain barrier. It was determined that the risks of hepatotoxicity, carcinogenicity, immunotoxicity, and mutagenicity were low. As a result, these metal complexes are evaluated as potential therapeutic agents in the treatment of diseases such as Alzheimer’s disease, glaucoma, epilepsy, malaria, and cancer. The data obtained in this study emphasize the biological activities and pharmacological potential of the complexes, and it is recommended that they be supported by future in vivo studies.

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• MakaleAçık Erişim2025/r/gumushane/14179
  Development of the Disaster Risk Perception Scale: Evaluation of Its Impact on Disaster Preparedness

  Kiymis, Ibrahim; Kaya, Afsin Ahmet

  Objectives:Developing a disaster risk perception scale is a critical component of Disaster Risk Management (DRM), enabling the assessment and evaluation of the reactions, behaviors, and risk culture characteristics of individuals living under disaster risk. The objective of this study is to develop a disaster risk perception scale and to assess its effect on disaster preparedness. Methods: A pilot study was conducted with 359 participants, followed by a main study involving 786 participants. All participants resided in Giresun and Elazig, Turkey, the regions recently affected by earthquakes, floods, and landslides. Results:A reliable and valid disaster risk perception scale with 25 items and 5 dimensions (exposure/impact, probability, uncontrollable, worry/fear, and vulnerability) was developed. The disaster risk perception of the participants differed significantly according to their educational level, income level, city of residence, and disaster education. As per the multiple regression analysis, the exposure/impact and worry/fear variables had positive and significant effects on disaster preparedness. Conclusions:For future studies, it is recommended to implement the disaster risk perception scale across diverse disaster types to assess and evaluate the outcomes effectively.

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• Derleme MakaleAçık Erişim2023/r/gumushane/14520
  Climate change in Türkiye and its impact on oncology nurses

  Kaya, Afşin Ahmet; Aydin, Aydanur; Bağcivan, Gülcan

  Climate change threatens human life and health by negatively affecting the basic components of health such as clean air, safe drinking water, nutritious food supply, and safe shelter. Türkiye is a country that is largely exposed to climate change with its cosmopolitan location, which is a bridge between Asia and Europe. Due to climate change, serious effects are seen in all sectors from energy to agriculture, from the economy to health. Climate change is defined as the most important global health threat of the next century, and the problems it brings are seen as the most important pressure factor for the life opportunities of future generations. Food and fresh water availability, rising sea levels, abnormal weather events, migration, and diseases are thought to affect human health. A multidisciplinary approach is required to adapt to climate change’s health effects and reduce its negative health effects. In addition, it is predicted that diseases that are about to disappear will re-emerge and become threats. It is thought that as a result of the contamination of food and water resources with the changing ecosystem, some infections will increase and society will face them. Nurses are both affected by climate change and its effects on public health. Nurses who remain in this situation have a great role in providing effective awareness for raising public awareness. In recent years, oncology clinics have not been affected by fire, earthquakes, and pandemics in our country. In this respect, it can be stated that the health service in Turkish oncology clinics is carried out uninterruptedly and by experts in the field. We learned during the pandemic that the whole world is unprepared for the future effects of climate change. In this direction, nurses should think about solutions for the problems related to climate change in the future.

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• MakaleYalnız künye2023/r/gumushane/14514
  Assessment of Knowledge, Emotion, and Attitude Levels of Kindergarten and Elementary School Teachers on the Disaster Management and Pediatric First Aid

  Kaya, Afsln Ahmet; Ayker, Bereket

  Objectives: This study's aim is to assess the disaster management and pediatric first aid-related knowledge, emotion, and attitude levels of of kindergarten and elementary school teachers, as the professionals that are first to provide interventions in the case of a disaster to children ages 0-8, who are considered to be among the vulnerable groups in the context of a disaster. Methods: A total of 119 teachers working in the kindergarten and elementary schools located in the GÜmÜşhane province of Turkey were included in the study and were asked to fill in a questionnaire that comprises 3 sections. Data collection tools included a sociodemographic questionnaire, teachers' disaster management knowledge levels, and teachers' pediatric first-aid knowledge, emotion, and attitude levels. Results: Analysis of the scores obtained by the teachers from the questionnaire revealed that the teachers, who participated in the study, had a high level of disaster management knowledge and a moderate-to-high level of pediatric first aid knowledge. Conclusions: It is suggested as a result of this study that the disaster risks and injuries or losses of life associated with disasters that may occur at schools may be reduced with disaster management and first-aid interventions.

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• Derleme MakaleYalnız künye2021/r/gumushane/17474
  Küresel İklim Değişikliğinin Psikolojik Boyutu

  Akbulut, Meryem; Kaya, Afşin Ahmet

  İnsanoğlunun ihtiyaçları sınırsızdır. Sürekli bir tüketim ve üretim halindedir. İhtiyaçlarını karşılamak için sanayi devriminden bugüne kadar bilinçsiz bir şekilde hareket edilmiş ve doğa üzerinde telafisi imkansız hasarlara neden olunmuştur. Çevreye ve atmosfere zarar verici etkilerin giderek artmasıyla beraber ekosistemin dengesi bozulmuştur. Bir süre sonra bozulan denge insanlar için bir tehdit haline gelmiştir. Tehdidin adı ise küresel iklim değişikliğidir. Dünya üzerinde yaşayan her bireyi çeşitli şekillerde etkileyen bu felaket artık insanların sağlıkları üzerinde de olumsuz etkiler yaratmıştır. İklim krizinin sadece fiziksel değil psikolojik olarak da oluşturduğu olumsuz etki ciddi bir sorun haline gelmiştir. İklim değişikliğinin günümüzde sebep olduğu tek bir olumsuz olay şuan ki haliyle sadece o günü etkileyebilir. Ancak bireylerde bıraktığı travma uzun süre etkisi geçmeyecek bir durumdur. Ayrıca gerekli tedbirlerde geç kalınmasında yine psikolojik engeller etkilidir. Hızlı bir şekilde önlem alınmazsa iklim değişikliğinin negatif etkileri gelecek dönemlerde devam edeceği için sürekli maruziyet yaşamak toplumunda ruh sağlığını bozacaktır. Bu çalışma kapsamında küresel iklim değişikliğinin psikolojik boyutu incelenerek gerekli çıkarımlar yapılmıştır. İklim krizine karşı toplu ve hızlı şekilde tedbir almanın önemine dikkat çekilmiştir.

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• MakaleYalnız künye2020/r/gumushane/17920
  Bir Afet Olarak Küresel İklim Değişikliği ve İlkokul Öğretmenlerinin İklim Değişikliği Farkındalığının İncelenmesi: Gümüşhane İli Örneği

  Akbulut, Meryem; Kaya, Afşin Ahmet

  Küresel iklim değişikliğinin afet olarak önemi vegünümüzdeki en önemli çevre sorunlarından biriolması, bizi küresel iklim değişikliğiyle ilgili bilimekatkı sağlayacak bir çalışma yapmaya yöneltmiştir.Araştırma kapsamında öncelikle afetlere, ardındanküresel iklim değişikliğiyle ilgili genel bir literatüraraştırmasına yer verilmiştir. Araştırma kapsamındailkokul öğretmenlerinin iklim değişikliği farkındalığınıölçmek için, inanç, tutum, davranış ve bilgi altboyutlarından oluşan bir farkındalık ölçeğikullanılmıştır. Araştırmanın evrenini Gümüşhaneilinde görev yapan toplamda 300 ilkokul öğretmenioluşturmaktadır. Veri toplama sürecinin sonunda 214ilkokul öğretmenine ulaşılmıştır. Çalışmanın verileriAmos 23 ve SPSS 21 paket programlarında analizedilmiştir. Ortaya çıkan sonuçlar Gümüşhane ilindegörev yapan ilkokul öğretmenlerinin iklim değişikliğifarkındalıklarının yüksek olduğunu göstermektedir. Budurum araştırmanın amaçlarından olan iklimdeğişikliği farkındalığı yüksek bireyler yetişmesiaçısından önem arz etmektedir. Son olarak tartışma,öneri ve sonuç başlıklarıyla genel bir değerlendirmeyapılmıştır ve küresel iklim değişiklinin öneminedikkat çekilmiştir.

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• MakaleYalnız künye2020/r/gumushane/17672
  The Level of Perception of Hospital Personnel on Waste Management and Waste Management in disasters: Case of Gümüşhane Province

  Kaya, Afşin Ahmet; Küçük, Ümran Aysen

  The main objectives of disaster management are; to analyze the dangers faced by the society, to predict the situations that may be damaged by the event that may arise, to develop and implement strategies that will not allow secondary disasters. After disasters occur, different types of waste are generated depending on the type of disaster. If disaster waste is unmanageable, it can cause a secondary disaster. Hospitals, on the other hand, are health institutions that provide active service during disasters. Naturally, it is inevitable for hospitals to generate more waste in case of disasters. For this reason, hospitals should also have a waste management strategy for a possible disaster situation. Waste management, on the other hand, can be efficient with the employees' attitude, awareness and perception of waste. Within the scope of the research, a questionnaire was applied to the hospital staff. The questionnaire consists of three parts. The first part includes sociodemographic questions. The second part consists of Waste Management Awareness questions and Waste Management Awareness in Disasters questions. In the third part, there are Waste Management Attitude questions. The data of the study were analyzed with the SPSS 21 package program. It was determined that the awareness level of the participants was high, and their attitude level was medium. There is no significant difference in the mean score of the awareness level of the participants in terms of gender and age factors. Significant results were found in factors such as working time and education level.

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• Kitap BölümüYalnız künye2020/r/gumushane/13219
  Investigation of the Effects of the Disasters Occurred between 2010 and 2017 on the World Economy

  Turan, Melikşah; Oral, Vildan; Kaya, Afşin Ahmet

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• Kitap BölümüYalnız künye2020/r/gumushane/12998
  Investigation of global climate change and climate change project results of Gümüshane as a disaster

  Kaya, Afsin Ahmet; Akbulut, Meryem

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• MakaleYalnız künye2019/r/gumushane/18210
  Safe Hospitals and Rating in Disasters: Case of Gümüşhane Province

  Kaya, Afşin Ahmet; Kıymış, İbrahim

  Buildings, facilities, systems, critical services and people are greatly affected during disasters. When disasters occur, health facilities such as hospitals should be able to protect the life and welfare of the community. Therefore, there is a need for safe hospitals that do not collapse in disasters and continue to serve. The purpose of this study, which is required due to the existing shortcomings, is to determine the security levels of the state hospitals in Gümüşhane against disasters and to reveal the current status of hospitals. This study is descriptive. In the study, Safe Hospital section in the last section of 6 HAPs of Gümüşhane Province was investigated in 2018. The data of the study was collected by using the Safe Hospital Checklist which is composed of the dangers affecting hospital security, structural safety, non-structural safety and emergency and disaster management modules developed in the guide book Safe Hospital Safety Index: Guide for Evaluators Checklist published by WHO in 2015. Within the framework of current requirements, a total of 30 questions were included in the checklist, including 20 questions on CBRN-E (Chemical, Biological, Radiological, NuclearExolosive) and 10 questions on sensitive groups, referring to expert opinions. A total of 181 questions were examined along with the questions on the Safe Hospital Checklist.

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