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Koleksiyondaki öğeler
- MakaleYayıncıda açık erişim2020Complementary and Alternative Medicine Methods Used for Sleep Disturbance in Menopause
Özcan, Handan; Çakmak, Suzan; Salman, Ebru
Objective: One of the most common complaints observed during the menopausal period is sleep disorders, affecting 40%-60% women. In this study, we aimed to determine complementary and clternative medicine (CAM) for menopausal women experiencing sleep disturbances, and the prevalence and influencing factors of sleep disturbance. Materials and Methods: In this descriptive cross-sectional study, we included menopausal women experiencing sleeplessness [>= 4 degree of discomfort according to the Visual Analog Scale (VAS)] (n=201). A questionnaire and the CAM Scale were used to collect data. The necessary institutional and ethical committee permissions were obtained. Results: The mean age of the menopausal women was 47.23 +/- 4.53 [minimum (min)- maximum (max), 30-60] years, and their mean VAS for insomnia was 5.20 +/- 1.12 (min-max, 4-9). The following methods were used by the women to overcome insomnia: herbal supplements (96.6%), dietary supplements (98.8%), religious practices (95.7%), and mind-body practices (76.9%). The most common methods were fruits and vegetables, milk and dairy products, honey, linden tea, rosehip, prayer, pray, and music. Approximately 70.5% women expressed that the method they used was effective. Conclusion: Almost all menopausal women used any method of CAM. Further studies on the effectiveness of these methods as well as the training to be provided and the information dissemination by healthcare professionals are recommended.
AtıfWoS7OpenAlex12TR Dizin4
İncele - MakaleAçık Erişim2014Scopus SJRQ4Early and Late-Term Results of Arthroscopic Surgery on Patients with Gonarthrosis
Yilar, Sinan; Yildirim, Omer Selim
Objective: To provide guidance in the selection of the appropriate patient for arthroscopic debridement. Materials and Methods: Ninety patients who were diagnosed with gonarthrosis according to modified American College of Rheumatology (ACR) criteria and who underwent arthroscopic debridement and meniscectomy were evaluated. Functional assessment of patients was made based on preoperative as well as 1 month and 1 year postoperative results of the Lysholm Knee Score and the Visual Analog Scale (VAS). One year postoperatively, the Tapper-Hoover Scoring System was used to calculate long-term results. Analyses were conducted using SPSS 18 software. For this study ethics committee approval was received from the ethics committee of Ataturk University Medical Studies Department Head on 08.10.2010 at the 6th meeting with regards to the document written on 16.06.2010 with number 998. Results: Differences between preoperative and 1-month and 1-year postoperative values in the Western Otorino and McMaster Universities Osteoarthrosis (WOMAC) Index, Lysholm and VAS were found to be statistically significant (p<0.001) (Table 1). According to TapperHoover results, 82.8% of patients benefited from arthroscopic debridement in the long term (Table 2). Among body mass index (BMI) groups, the WOMAC, Lysholm and VAS values of obese patients were worse than those of normal weight and underweight patients, and the difference was statistically significant (p<0.005). Late-term results of patients younger than 55 were superior to those over 55. Conclusion: In the treatment of patients with gonarthrosis, arthroscopic debridement is a good option. Patients who have a low BMI and are younger than 55 years old experience more benefit from arthroscopic debridement.
AtıfWoS5OpenAlex5İncele - MakaleAçık Erişim2020Evaluation of Patients Infected with Human Immunodeficiency Virus Followed in Our Clinic
Kurt, Esma Kepenek; Kandemir, Bahar; Erayman, Ibrahim; Bulut, Rukiyye; Bitirgen, Mehmet
Introduction: The number of people infected with human immunodeficiency virus (HIV) in our country is increasing day by day. In this study, epidemiological, clinical, laboratory features, treatment regimens and side effects of HIV/AIDS cases followed in our clinic were evaluated. Materials and Methods: Fifty-four patients who were followed up with HIV infection in our clinic between 2000-2018 were examined retrospectively. Results: Of the 54 patients, 18 (33.3%) were females and 36 (66.7%) were males. Mean age was 42.0 +/- 15.2 (18-70) years. Mean duration of the disease was median 3 (0.5-28) and the duration of clinical follow-up was 3.3 +/- 2.7 (0.5-10) years. A total of 44 (88%) patients had risky sexual contact, and nine women were infected by her husband. The first complaint of the patients for admission to our clinic was weakness (22.2%) and fever (9.3%). Patients were diagnosed most frequently during routine examinations (48%). Mean CD4 count of the patients at the time of admission was 317.2 +/- 247.7 (7-918) cell/mm(3), and HIV-RNA was median 61000 (0-30000000) copy/mL. The most frequent treatment was tenofovir disoproxil fumarate-emtricitabine and lopinavir/ritonavir (TDF-FTC and LPV/r) in 24.4% of the patients. Treatment was changed in 14 (25.9%) patients. In five patients, noncompliance to treatment and in five patients, side effects were encountered, and treatment was changed. Hyperlipidemia was the most common side effect (52.9%) in patients receiving treatment. Prophylaxis was given to 50% of the patients in terms of opportunistic infections at the beginning of treatment. One patient had gonococcal urethritis and one patient had HPV infection in the cervix. Four patients discontinued treatment and 46 patients continued treatment. One female patient was exitus. Conclusion: The number of HIV/AIDS patients, a chronic disease, is increasing also in our country. Early diagnosis of these patients should be made, and the disease should be controlled by providing access to treatment and suppression of viral load.
AtıfWoS2OpenAlex2İncele - MakaleAçık Erişim2022The Relationship between the Use of Complementary and Alternative Medicine in Cardiovascular Diseases with Self- Care Ability and Life Quality
Kulakaç, Nursen; Uzun, Sevda; Sayilan, Aylin Aydin
BACKGROUND/AIMS: Cardiovascular diseases are one of the leading global causes of morbidity and mortality. Lifestyle changes are critical for the prevention of cardiovascular diseases and improving self-care levels during treatment. This study aimed to explore the relationship between the use of complementary and alternative medicine (CAM) and the quality of life and self-care ability in individuals with cardiovascular disease.MATERIALS AND METHODS: The study population in this cross-sectional and correlational research consisted of cardiovascular patients hospitalized in a public hospital between 1st April and 30th June 2018. One hundred and six patients agreeing to participate in this study were selected for sampling. A Patient Information Form, the Exercise of Self-Care Scale, and the World Health Organization Quality of Life Scale-Short Form were employed as the data collection tools.RESULTS: The mean age of the patients in this study was 62.83 +/- 1.40 years, 59.4% were women, and 34.0% had coronary heart disease. The patients' mean self-care score was 101.18 +/- 22.31, and their mean quality of life score was 28.61 +/- 9.50. Age, education, diagnosis and duration of disease, constipation, and CAM use were found to affect their quality of life (p<0.005). A positive correlation was determined between CAM use and self-care ability.CONCLUSION: The use of CAM in individuals with cardiovascular disease has a positive effect on self-care ability and enhances their quality of life.
- MakaleAçık Erişim2024Scopus SJRQ2The effect of motivational interviewing on quality of life and self-efficacy behaviors of individuals with chronic illness: A meta-analysis study
Uzun, Sevda; Guerhan, Nermin
ObjectiveThis study aims to reveal the effect of the motivational interviewing on the quality of life and self-efficacy behaviors of individuals with chronic diseases.Material-methodFor this meta-analysis study, PubMed, Web of Science, EBSCOhost, Google Scholar, and Y & Ouml;K Theses databases were searched in January-May 2021 without year limitation. As a result, 38 studies were included in the study: 23 for the quality of life variable, and 21 for the self-efficacy behaviors variable (in 6 studies, both variables were examined together). The data were synthesized with meta-analysis and narrative methods. The total sample size of the studies is 25,425.ResultsThis meta-analysis study showed that the motivational interviewing applied to individuals with chronic diseases changed their quality of life (SMD: 0.296, %95 CI: 0.054-0.537, Z = 2.402, p = .016, I2 = %95). The type of chronic disease, measurement tool, sample group, disease group, age range, and whether the motivational interviewer was a nurse or not changed the effect size of the motivational interviewing on the quality of life. The self-efficacy score average of the experimental group to which motivational interviewing was applied was statistically similar to that of the control group (SMD: 0.141, %95 CI: -0.065, 0.347; Z = 1.346, p = .178, I2 = %87).ConclusionsAs a result of the meta-analysis, it was determined that the use of motivational interviewing increased the quality of life level of individuals with chronic diseases. However, it is thought that more research is needed because some studies were conducted with small sample size and prepost test design. The results of the study may provide guidance on the interventions to be used in improving the quality of life of individuals with chronic diseases.
AtıfWoS8OpenAlex8
İncele - MakaleAçık Erişim2012Scopus SJRQ2Behcet's disease with aneurysm of internal iliac artery and percutaneous treatment
Memetoglu, Mehmet Erdem; Kalkan, Asim
Behcet's disease (BD), described in 1937 by Hulusi Behcet, is a multisystemic inflammatory disorder. In this paper, we report a large pseudoaneurysm of the internal iliac artery in a patient who had BD, and was admitted to emergency service complaining of leg pain and the percutaneous treatment of the pathology which followed.
AtıfWoS10OpenAlex12İncele - MakaleAçık Erişim2013Scopus SJRQ3Comparison of the safety and efficacy of ivabradine and nebivolol mono- and combination therapies in the treatment of stable angina pectoris patients with left ventricular dysfunction
Kutlu, Rasim; Memetoglu, Mehmet Erdem; Muratalievic, Tolkun Murataliev
We aimed to investigate the pharmacoeconomic efficacy of ivabradine and nebivolol in treatment of stable angina pectoris patients with left ventricular dysfunction prospectively. Pharmacoeconomic analysis was performed by using cost minimization analysis, and cost effectiveness analysis. After 6 months' treatment LVEF for the nebivolol group (17 patients, 50%) improved by (38 +/- 6.5) to (41 +/- 3.2), (p>0.05) and for the ivabradine group (17 patients, 50%) (37 +/- 5.4) to (41 +/- 2.3), (p>0.05), mean MET value in the nebivolol group increased from (3.7 +/- 1.2) to (5.5 +/- 1.6), (p>0.05), versus from (3.6 +/- 1.5) to (5.5 +/- 1.4), (p>0.05) in the ivabradine group, cost minimization analysis results showed a difference in the total cost of treatment was US$ 5288.7 in favor of nebivolol. The findings suggest that nebivolol is more cost-effective than ivabradine in the treatment of patients with left ventricular dysfunction.
AtıfWoS2OpenAlex2İncele - MakaleAçık Erişim2020Scopus SJRQ3The Effects of Boron (Orthoboric Acid) Supplementation into Diets on Serum Lipid and Protein Profiles of Hens During Late Laying Period
Kaya, Hacer; Macit, Muhlis
This study was carried out to determine the effects of boron addition into the diets on serum parameters of hens. A total of 288 Lohman laying commercial hybrid chickens of 62 weeks were fed for 12 weeks with four different rations containing basal feed 0 (B0), 50 (B50), 75 (B75) and 150 (B150) mg / kg B. Each group was replicated in 18 cages, four hens per cage. During the study, 16 hours lighting program was applied, feed and water were given as ad-libitum. The effect of boron supplementation was not significant on the rates of diacylglycerol and hydrocarbon+cholesterol esters (P>0.05) but the rates of polarlipid, triacylglycerol (P<0.05), and serum total cholesterol (P<0.01) were found significant. Lipid peroxidation values of groups fed with diets including 75 and 150 mg/kg B were determined lower than others. Addition of ration B affected different molecular weight proteins at different levels. In conclusion, it has been determined that the addition of B at different levels into the diets of laying hens during late laying period significantly influenced the serum lipid peroxidation, serum lipid and serum protein profile, but further researches are needed to clarify the changes related to the effects of B addition into diets on mentioned parameters of laying hens.
AtıfTR Dizin1İncele - MakaleYalnız künye2018Assessment of knowledge level of university students about ovarian cancer
Demir Dogan, Melike; Aygün, H. Gulbahar; Baskin, Sema; Sensoy, Merve; Köken, Elif
The present study was conducted in order to determine the knowledge levels of female university students about ovarian cancer. The sample was planned to include 2220 students however 1468 students were reached. The data were collected via questionnaire about socio-demographic characteristics of the students and questionnaire involving expressions that measure their knowledge level. Mean age of the students was 20.78 +/- 1.20; 678 (46.1%) of the students were faculty students, 466 (31.7%) were collage students, and 324 (22.0%) were vocational school students. 874 (59.5%) of the students did not know what ovarian cancer is and 1332 (90.7%) did not receive any education about ovarian cancer. Therefore, 1227 (83.6%) of the students stated that they did not know symptoms of ovarian cancer. Thestudents were determined to have low level of knowledge about ovarian cancer
AtıfWoS1İncele - MakaleYalnız künye2026Scopus SJRQ1Temporofacial (TemFa) Lift
Kaderi, Sina; Ekinci, Can; Köse, Aydan Ayse
Background Today, people increasingly embrace the natural process of aging while seeking to age gracefully and elegantly. As a result, there has been growing interest in facelift and facial rejuvenation techniques. Patients tend to prefer methods that refresh the facial expression, offer natural-looking results, and leave minimal scarring. Objectives The authors describe a new technique and its tips that include short-scar facelift in addition to forehead and midface lift, especially for patients between the ages 35 and 50 with moderate skin sagging and excess. This procedure also includes intervention on the platysma muscle and all major retaining ligaments. Methods Seventy-four patients, all female, who were operated on with the TemFa lift technique described by the author, were evaluated with midface area measurements and Brow Positioning Grading Scale (BPGS), and the preoperative and postoperative results are presented. Results Compared with the preoperative results, the ratio of the upper midface area (P1) to the lower midface area (P2) increased significantly in the postoperative period (p < 0.05), while the BPGS results decreased significantly (p < 0.05), resulting in a younger eyebrow height and position. After the operation, the square face appearance is replaced by a more youthful V-shaped face. Conclusion TemFa lift technique can be considered as a suitable surgical technique for patients between the ages 35 and 50 who have moderate excess skin and sagging but also want some improvement in the neck and jawline area.
- MakaleYalnız künye2012Scopus SJRQ2Endovenous ablation with a 940 nm laser for the treatment of great saphenous vein insufficiency: short- to mid-term results
Memetoglu, Mehmet Erdem; Kurtcan, Serpil; Erbasan, Ozan; Özel, Deniz
PURPOSE We aimed to present the short- to mid-term results of endovenous laser ablation (EVLA) procedures that were used to treat great saphenous vein (GSV) insufficiency. MATERIALS AND METHODS This prospective study was conducted between December 2009 and January 2011. A total of 112 incompetent GSVs were treated using EVLA with a 940 nm wavelength laser. Ninety patients were treated for varicose veins with saphenous reflux, including 36 females (40%) and 54 males (60%). These patients' ages ranged from 17 to 79 years (median, 48 years). After the EVLA, the patients were monitored using duplex ultrasonography and were assessed clinically at 1 week and 1, 3, 6, and 12 months after the surgery. The patients were scheduled for a three-day examination after the EVLA to assess the level of pain that each patient was experiencing in each limb. RESULTS At the end of a one-year follow-up period, the postprocedural duplex scans revealed a total occlusion of the treated GSVs in 88 (97%) patients and a sub-total occlusion in two (2%) patients. The average modified clinical, etiological, anatomical, and pathological score was significantly decreased at 12 months. The following complications were observed in the present study: hypoesthesia (11%), swelling and induration (5%), skin pigmentation (5%), deep vein thrombosis (1%), erythema (1%), and bleeding (1%). The mean visual analog pain score for the entire procedure was 3.14 +/- 1.06. CONCLUSION Our short- and mid-term results of the EVLA procedure were satisfactory, and the results of this study reaffirmed the safety and effectiveness of an EVLA using a 940 nm wavelength for the treatment of GSV insufficiency.
AtıfWoS10OpenAlex18İncele - MakaleAçık Erişim2024Empirical Analysis of Turkish Banking Sector Institutional and Macroeconomic Determinants of Risks
Akyol, Hikmet; Basar, Selim
This research examines the macroeconomic and institutional sources of individual, systemic, and systematic risks in the Turkish banking sector. The period between 2008:Q3 and 2019:Q3 of the nine deposit banks selected for this purpose were estimated using panel data analysis estimators. The results indicate that selected macroeconomic and institutional variables affect banking risks. These findings are important for revealing the institutional and macroeconomic sources of risks in the Turkish banking sector. Therefore, the results contain significant propositions for researchers, market participants, and politicians. Market participants and researchers can anticipate defaults and financial instability using selected macroeconomic and institutional variables. The estimation results reveal Turkish banks' institutional soundness and financial performance strength. In addition, the extent to which banks are effective intermediaries in the sector was analysed. This research documented a strong link between global market indicators and banking risks
AtıfOpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ3SOME PHYSICOCHEMICAL, COLOR, COOKING, BIOACTIVE AND SENSORY PROPERTIES OF TURKISH NOODLES: ENRICHED WITH ARONIA POWDER (ARONIA MELANOCARPA)
Karademir, Emine; Yuksel, Ferhat; Baltaci, Cemalettin
Aronia (Aronia melanocarpa) is a fruit with a high polyphenol content, and its use is increasing due to its potential health effects with increased polyphenol content. The widespread consumption of Turkish noodles and similar products in society is important for increasing their nutritional quality. The aim of this study was to evaluate the physicochemical, color, bioactive, and sensory properties of noodle samples to which aronia powder was added at different concentrations of 2%, 4%, 6%, 8%, and 10%, respectively. Total Polyphenol Content (TPC), Total Antioxidant Capacity (TAC), and Total Flavonoid Content (TFC) amounts were found to be significantly increased (p<0.05). In addition, significant increases were found in the antioxidant activity (ABTS(center dot+), DPPH and FRAP) of the samples. According to the sensory evaluations, the noodles with 8% aronia had a high level of general acceptability, while the group with 10% aronia had a lower level. Consequently, we observed that adding aronia could yield an acceptable noodle enriched in bioactive components.
- MakaleYalnız künye2021The Effect of Foreign Trade By Technology Intensity on Economic Growth: The Case of Turkey
Akyol, Mehmet; Mete, Emrullah
In today's international trade conditions, countries need to complete their technological developments in order to increase their competitiveness and economic growth. High technology exports are very important, especially for countries aiming for export-oriented growth. In this study, the effect of export and import performance according to technology intensity on the economic growth were analyzed for Turkey. In this context, data for the period 2002-2018 were analyzed with the ARDL boundary test approach. According to the analysis results, it was determined that low, low-medium, medium-advanced and advanced technology exports and imports and economic growth are co-integrated.
AtıfTR Dizin4İncele - MakaleAçık Erişim2021Scopus SJRQ3Erectile dysfunction treatment with Phosphodiesterase-5 Inhibitors: Google trends analysis of last 10 years and COVID-19 pandemic
Deger, Muslim Dogan; Madendere, Serdar
Objectives: We aimed to analyze the trend change of the most popular Phosphodiesterase-5 Inhibitors (PDE5i) over time and geography by using Google Trends (GT) data in 10 years period and COVID-19 pandemic. Materials and methods: GT is able to generate a line-graph, showing how interest has increased or decreased over a period within specific territories. The search values for specific terms are indexed as relative search volume (RSV), which is presented on a scale from 0-100. Avarage annual percentage change (AAPC) and RSV were analyzed to evaluate gain or loss of interest in trends. Search terms were generated for Food and Drug Administration (FDA)-approved PDE5i; tadalafil, sildenafil, vardenafil, avanafil, and their most-used brand names. The data was within worldwide from 1 January 2010, to 31 December 2020, using the global query category. Results: The overall interest in PDE5i has doubled. Sildenafil has become the most trend PDE5i of today with a regular increase (AAPC: 0.016, p < 0.01). Although the search trend of tadalafil remained almost constant until 2014, the rate of increase in the last 6 years raised and tadalafil has become the 2nd most popular PDE5i recently (AAPC: 0.007, p < 0.01). For vardenafil there has been a decreased interest (AAPC: -0.009, p < 0.01). There is no significant change in avanafil trend (AAPC: 0.000, p: 0.5). All PDE5i interest on GT decreased notably from February to June 2020. But after June, search trends reached the level before the COVID-19 period in a month. Conclusions: These findings show us, with its increasing prevalence, erectile dysfunction (ED) has become a major public health problem. People from different geographies search the Internet for ED treatment options. Patients should be informed that ED may be the first sign of many comorbid diseases, and patients with ED should be referred to a health institution for diagnosis and treatment.
AtıfWoS11OpenAlex13İncele - BildiriYalnız künye2013Scopus SJRQ1Automated Functional Imaging in Atrioventricular Delay Time Optimization in Patients with Dual Chamber Pacemakers
Arik, Osman Ziya; Kalkan, Gulhan Yuksel; Sahin, Durmus Yildiray; Elbasan, Zafer; Gür, Mustafa; Kuloglu, Osman; Tekin, Kamuran; Gençaslan, Murat; Türkoglu, Caner; Uçak, Haci Ali
- MakaleAçık Erişim2025Scopus SJRQ4First Aid Self-efficacy in Mothers of Children Aged 0-4 Years: The Gümüşhane Example
Göger, Berrin; Kahriman, Ilknur; Çolak, Bahar
Introduction: The high relationship between the effective application of first aid after home accidents and survival determines the priorities in first aid. Childcare is mostly the responsibility of mothers, and their knowledge and practices regarding the management of home injuries are crucial in reducing morbidity and mortality associated with home accidents. This study aimed to examine the first aid self-efficacy of mothers with children aged 0-4 years to manage their children's home accidents. Methods: This cross-sectional study, focusing on the first aid self-efficacy of mothers with children aged 0-4 for home accidents, was conducted with 266 mothers at a district government hospital affiliated with the Ministry of Health in the Eastern Black Sea Region between January 1, 2023, and August 1, 2023. Data were collected through a demographic information form and the first aid self-efficacy scale for home accidents. Results: The mean score of the first aid self-efficacy scale in home accidents was found to be 2.15 +/- 0.95 and significant differences were found according to the mother's level of education, number of children, income status, caregiver of the child and mothers' first aid status. Conclusion: In conclusion, the findings of the study showed that first aid self-efficacy is not based solely on demographic factors, but instead may be shaped more by education, experience and the general approach of parents as parents, although mothers' knowledge of first aid was below average.
AtıfOpenAlex3TR Dizin2İncele - MakaleAçık Erişim2021Relationship between androgen levels and neutrophil/lymphocyte ratio in patients diagnosed with hirsutism
Sayilan, Samet; Mert, Meral; Kulakac, Nursen
Aim: Hirsutism is a disease involving increased terminal hair growth in women with a male-type distribution pattern in androgen-sensitive areas such as the chin, upper lip, chest, abdomen, back, and thighs. Our review of the available literature revealed no previous studies concerning the role of the peripheral blood neutrophil/lymphocyte ratio (NLR), an easily calculated and noninvasive marker, in hirsutism. The purpose of this research was to determine the relationship between androgen levels and NLR in female patients diagnosed with hirsutism. Material and Methods: The files of 392 patients presenting to the Bakirkoy Dr. Sadi Konuk Education and Research Hospital due to hirsutism between 2018 and 2020 were included in this cross-sectional, retrospective study. Patients' hirsutism and menstrual cycles, age at menarche, number of pregnancies in the case of married women, number of living children, and history of infertility were investigated. Hyperandrogenemia findings, such as hair loss and acne, were also recorded. Patients' biochemical and complete blood count parameters were evaluated. Results: The mean age of the participants was 26.27 +/- 6.37 years (min-max: 16-48), and their androgen levels were statistically significantly associated with high-density lipoprotein, hemoglobin, hematocrit, 17-hydroxyprogesterone, and HbA1c levels (p<0.05). However, no significant relationship was found between patients' androgen levels and NLR values (p>0.05). Discussion: No significant relationship was determined in this study between androgen levels and NLR values in women diagnosed with hirsutism. Due to the limited numbers of previous similar studies, further research with larger patient numbers is now needed.
AtıfWoS1İncele - EditoryalYalnız künye2017Scopus SJRQ3Spontaneous laryngeal abscess causing dysphagia
Ata, Nurdogan; Özcan, Irfan Firat
AtıfWoS1OpenAlex1İncele - MakaleAçık Erişim2018Scopus SJRQ4Comparison of Different Dynamic Contrast Enhanced-Magnetic Resonance Imaging Descriptors and Clinical Findings Among Breast Cancer Subtypes Determined Based on Molecular Assessment
Dogan, Serap; Ozmen, Soner; Oz, Bahadir; Imamoglu, Hakan; Kahriman, Guven; Zararsiz, Gokmen; Ozturk, Mustafa
Background: Breast cancer is a heterogeneous disease with different molecular and histologic subtypes, clinical behaviors and prognosis. The same stage of disease and similar histopathological characteristics may show different treatment responses. Identification of breast cancer subtypes has become important for planning the targeted therapy and personalized management of patients. Objectives: To compare the clinicopathologic findings, dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) characteristics and associated MRI findings among breast cancer molecular subtypes. Patients and Methods: 267 pathologically proven invasive breast cancers in 263 patients were included. Clinicopathological findings, DCE-MRI findings and associated MRI findings were retrospectively evaluated and compared among breast cancer subtypes. Results: Invasive ductal carcinoma was the most common histological tumor type (87.6%). There were 222 (83.1%) masses and 45 (16.9%) non-mass enhancements. The molecular subtypes were luminal A in 174 (65.1%), luminal B in 45 (16.9%), human epidermal growth factor receptor 2 (HER2) positive in 24 (9%) and triple negative (TN) in 24 (9%) of the lesions. Spiculated mass margin was significantly associated with luminal A breast cancer (45.2%) and irregular shape was significantly more common in luminal A (86.3%) and luminal B lesions (95.1%) (P < 0.001). Larger mass size (P= 0.027), non-mass enhancement (P= 0.005), perilesional+ prepectoral edema and skin + perilesional+ prepectoral edema were significantly associated with HER2 positive breast cancer (P= 0.001). Higher histological grade, oval mass shape, circumscribed mass margin, intratumoral high/very high signal intensity on T2 weighted image (T2WI) were significantly associated with TN breast cancer (P < 0.001). Conclusion: Histological grade, size and morphological features of masses on DCE-MRI, intratumoral signal intensity on T2WI and edema pattern would be helpful to distinguish breast cancer subtypes.
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