Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleYalnız künye2026
    Women's breast cancer prevention behaviors and cancer fears: the sample of post-earthquake

    Aydin, Aydanur

    In the event of a natural disaster, women who assume multiple roles within the family unit tend to postpone their health concerns and delay medical appointments. The present study aims to examine the relationship between the level of fear of breast cancer and the implementation of breast cancer preventive behaviours among women following an earthquake. The sample consists of 2,671 women aged 20 and over who participated voluntarily. The data were collected using two instruments: the Breast Cancer Fear Scale and the Women's Breast Cancer Prevention Behaviors Form. Following a comprehensive review of the extant literature, it was determined that women affected by earthquakes exhibited elevated levels of fear of breast cancer. A substantial decline was observed in the utilization of preventive measures necessitating institutional access, including mammography. The findings of this study indicate that education, occupation, and family history of breast cancer have a significant impact on women's post-earthquake fear levels in implementing preventive behaviours. However, given the cross-sectional design and the absence of pre-disaster baseline data, these findings reflect post-earthquake associations rather than temporal or causal trends. Natural disasters can result in the deterioration of health perceptions, exacerbated by heightened stress and health concerns. Consequently, there is an urgent need for innovative approaches to ensure the maintenance of health check-ups and continuous access to preventive care in the aftermath of large-scale natural disasters.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2026
    Immersive Virtual Reality as a Tool to Reduce Anxiety and Distress in Patients With Breast Cancer During Radiotherapy

    Aydin, Aydanur; Uslu, Gonca Hanedan; Gursoy, Ayla

    Background: – Virtual reality (VR) can be an innovative method to reduce patients’ anxiety and support their psychological health. Objective: – To evaluate the anxiety and distress-reducing effects of using immersive VR (IVR) intervention in breast cancer patients undergoing radiotherapy (RT). Methods: – Sixty breast cancer patients undergoing RT were recruited for the quasi-experimental study. The participants were divided into the intervention group and the control group. Anxiety and distress, the primary outcome measures, were assessed before the first and after the last radiation session using reliable scales. Patients in the intervention group watched a tranquil forest view with birdsong and meditation music during each RT session using IVR goggles. Results: – Both group patients had similar levels of anxiety and distress before the start of RT. After the intervention, the anxiety and distress of the patients in the intervention group decreased significantly compared with the control group. In addition, treatment-related comfort was higher in the intervention group. Overall, the majority of patients in the intervention group expressed a high level of satisfaction with this IVR experience. Conclusion: – Patients who experienced an IVR intervention showed less anxiety and distress, greater comfort, and higher satisfaction. This innovative technique can be used as a practical solution to alleviate anxiety and distress in various healthcare settings. Implications for Practice: – Immersive VR can be used in treatment and care interventions that cause anxiety and distress in oncology patients.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2024
    Changes in acute and late toxicity and patient-reported health-related quality of life following radiotherapy in women with breast cancer: A 1-year longitudinal study

    Uslu, Gonca Hanedan; Aydin, Aydanur; Gürsoy, Ayla

    Objective: The objective of this study was to investigate the frequency of acute and late toxicities, as well as changes in the quality of life (QOL) for breast cancer patients following radiotherapy (RT). Materials and Methods: A total of 108 breast cancer women were recruited for this prospective study. Data were collected at various intervals; prior to, and 1, 3, 6 months, and 1 year after radiation therapy. The primary outcomes were toxicity radiation therapy oncology group/European Organization for Research and Treatment of Cancer (EORTC) criteria. Our secondary outcome was QOL, measured using EORTC QLQ-C30 and Edmonton Symptom Assessment Scale. We employed Friedman's two-way analysis to evaluate the changes in QOL over the course of 1 year. Results: The early toxicities that are most commonly experienced include pharyngeal, skin, and mucous membrane toxicity. Late toxicities frequently involve skin and submucosal toxicity. To measure patient functionality, all functional subscale scores except for the patient's emotional state increased over time compared to pre-RT. Symptoms of the patients, which were included in the QOL symptom scale, decreased during the follow-up period, except for fatigue; however, changes in pain, insomnia, and loss of appetite did not significantly change. We identified the analogous symptom profiles in Edmonton. Although patients' overall health scores declined in the 1 st and 3 rd months after radiotherapy (RT), they rebounded at 6 and 12 months. Conclusion: For breast cancer patients, RT did not adversely affect functional capacity or exacerbate symptoms, but persistent fatigue did increase during the observation period. Health-care professionals ought to devise strategies to assist patients with skin toxicity and fatigue.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • BildiriYalnız künye2023
    Shape of Masses in Contrast Mammography Images and First Order Statistical Features Classification Based on

    Kobya, Mehmet Emin; Ture, Hayati; Dogan, Ramazan Ozgur; Kayikcioglu, Temel; Teymur, Aykut; Kul, Sibel

    Mammography is a valuable tool in the diagnosis and staging of primary breast cancer. Contrast-enhanced mammography (CEM) combines an iodinated contrast agent with traditional mammography to increase diagnostic accuracy, especially in women with more dense parenchymal background patterns. In this study, a Decision Support System (DSS) is proposed that classifies masses using radiomic features obtained from masks of benign and malignant masses in images obtained with the CEM technique. An open-access database containing 2006 CEM images was used in this study. Radiomic features obtained from these images were used to identify differences between benign and malignant masses. The DSS uses these features to classify masses using a decision tree algorithm. This study highlights the importance of the use of iodinated contrast agents to improve diagnostic accuracy in women with more dense parenchymal background patterns. Additionally, it emphasizes the potential benefits of a DSS, in combination with radiomic features, in the diagnosis and staging of breast cancer. In conclusion, this study demonstrates that the use of radiomic features in mammography images obtained with the CEM technique is an effective way to classify benign and malignant masses.The use of this technology could be an important tool in the early diagnosis and accurate classification of breast cancer.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023
    Mobile care app development process: using the ADDIE model to manage symptoms after breast cancer surgery (step 1)

    Aydin, Aydanur; Gürsoy, Ayla; Karal, Hasan

    The use of mobile applications is widespread in patient monitoring or education today. This study aims to describe the design and development process of a mobile app that supports patient self-care after breast cancer surgery. We used the ADDIE model to develop and test the mobile app. ADDIE (Analysis, Design, Development, Implementation, Evaluation) is a systematic approach based on a standard instructional design model for creating training materials. The model consists of five phases, each with its own set of steps. Once the steps within each phase are completed, the model progresses to the next phase, ultimately resulting in a “usable” product. Different team collaborations were established within each phase, and support was obtained from multiple experts during the design process. Thanks to this model, the information that patients need was transformed into a technological product. This article, which explains the stages of the product design process for mobile applications, provides information that may be helpful to researchers working on similar products.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023
    Breast cancer-related apps in Google Play and App store: evaluate their functionality and quality

    Aydin, Aydanur; Gursoy, Ayla

    Aim: This study aimed to evaluate the functionality and quality of breast cancer apps that can be accessed from Turkey. Methods: In this study, a systematic search strategy was used to identify free mobile apps on breast cancer available in the App and Google Play stores. According to the study’s PRISMA flowchart, 707 apps met the inclusion criteria. The Mobile App Rating Scale (MARS) assessed the quality of the apps. Results: Mobile apps focused on the categories of communication, education, and treatment order/plan. The mean MARS quality score for all apps was 3.4, and according to the mean score of the subscales, they were categorized as functionality, aesthetics, information quality, and participation. In addition, the mean scores of the subscales were listed on MARS as functionality, aesthetics, knowledge quality, and participation. Conclusion: Nowadays, “e-health” apps are attracting attention in the treatment of health problems. While the apps in download stores appear to provide basic information about breast cancer, they offer limited and personalized problem management related to prevention, early detection, and screening. Support from healthcare professionals and further efforts can be made to develop innovative technologies and apps that include evidence-based informational content about breast cancer. Implications for Cancer Survivors: In the process of breast cancer information, survivors can be encouraged to manage this process using e-health services.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • Derleme MakaleAçık Erişim2023
    “Who am I?” A qualitative meta-synthesis of Chemotherapy‐induced alopecia and body image perception in breast cancer patients

    Kocan, Sema; Aktug, Cemile; Gursoy, Ayla

    Background: Since alopecia may be the first physical evidence and sign of cancer diagnosis and treatment, it may have a more serious and challenging effect on a woman than the loss of breast tissue. Objective: The purpose of this study was to summarize the current qualitative research which explores the body image perceptions of breast cancer patients with chemotherapy-induced alopecia. Material and methods: We searched three electronic databases and reviewed studies from December 2011 to December 2021 for qualitative results analysing the experiences of women with breast cancer and chemotherapy-induced alopecia. The Joanna Briggs Institute critical (JBI) appraisal tool was used to assess the quality of the targeted studies. The Meta-synthesis process developed by Sandelowski and Barroso was used to collect and analyse the data. Results: We discovered two main and five sub-themes from the meta-synthesis findings of 11 qualitative studies involving 225 women. The main themes were “I am not comfortable in this body” and “Who am I?”. The first main theme revealed patients’ intense reactions to their hair loss: “I'm in emotional chaos”, “I am looking for a place to hide” and “I knew it and now I’m experiencing it”.The second main theme of “Who am I?” contained two sub-themes: “What did my hair take from my femininity when it was gone?” and “Will I lose my partner after my hair?”. Conclusion: Meta-synthesis provided an up-to-date and integrated interpretation of scientific results about the experiences of women with breast cancer, alopecia, and their body image perceptions. This interpretation will facilitate a more comprehensive understanding of the alopecia-body image relationship. Thus, the aim of the meta-synthesis results is that these will contribute to nurses’ understanding of how alopecia, although a temporary symptom, affects women's perceptions of body image.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2020
    Lymphedema Information and Prevention Practices of Women After Breast Cancer Surgery

    Aydin, Aydanur; Gürsoy, Ayla

    AIM: This study was carried out to determine women's knowledge about lymphedema precautions and their practice status. The sample of this descriptive and correlationally designed study included 107 women who underwent surgery. METHOD: This descriptive study's data were collected using a questionnaire form developed by the researcher. The data were structured on a 3-point Likert-typescale.The one-way analysis of variance, correlations, and the Kolmogorov-Smirnov test were used in the statistical analysis. RESULTS: Three-quarters of the women knew that they should do arm exercises, keep the arm above the heart level while resting, and that blood pressure should not be measured, and jewelry not be worn. However, it was found that the percentage of women who did not know that the arm circumference should be measured at regular intervals or how to evaluate the arm circumference measurements and what to do in case of an injury was the same. It was determined that the precautions that the majority of women took in measuring lymphedema consisted of not measuring blood pressure, not wearing tight jewelry, and wearing an appropriate bra. CONCLUSION: It is thought that patients should be informed about the development of lymphedema after breast cancer surgery because their compliance with taking the precautions will be important in reducing the incidence, degree, and effects of lymphedema.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2018
    Comparison of Different Dynamic Contrast Enhanced-Magnetic Resonance Imaging Descriptors and Clinical Findings Among Breast Cancer Subtypes Determined Based on Molecular Assessment

    Dogan, Serap; Ozmen, Soner; Oz, Bahadir; Imamoglu, Hakan; Kahriman, Guven; Zararsiz, Gokmen; Ozturk, Mustafa

    Background: Breast cancer is a heterogeneous disease with different molecular and histologic subtypes, clinical behaviors and prognosis. The same stage of disease and similar histopathological characteristics may show different treatment responses. Identification of breast cancer subtypes has become important for planning the targeted therapy and personalized management of patients. Objectives: To compare the clinicopathologic findings, dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) characteristics and associated MRI findings among breast cancer molecular subtypes. Patients and Methods: 267 pathologically proven invasive breast cancers in 263 patients were included. Clinicopathological findings, DCE-MRI findings and associated MRI findings were retrospectively evaluated and compared among breast cancer subtypes. Results: Invasive ductal carcinoma was the most common histological tumor type (87.6%). There were 222 (83.1%) masses and 45 (16.9%) non-mass enhancements. The molecular subtypes were luminal A in 174 (65.1%), luminal B in 45 (16.9%), human epidermal growth factor receptor 2 (HER2) positive in 24 (9%) and triple negative (TN) in 24 (9%) of the lesions. Spiculated mass margin was significantly associated with luminal A breast cancer (45.2%) and irregular shape was significantly more common in luminal A (86.3%) and luminal B lesions (95.1%) (P < 0.001). Larger mass size (P= 0.027), non-mass enhancement (P= 0.005), perilesional+ prepectoral edema and skin + perilesional+ prepectoral edema were significantly associated with HER2 positive breast cancer (P= 0.001). Higher histological grade, oval mass shape, circumscribed mass margin, intratumoral high/very high signal intensity on T2 weighted image (T2WI) were significantly associated with TN breast cancer (P < 0.001). Conclusion: Histological grade, size and morphological features of masses on DCE-MRI, intratumoral signal intensity on T2WI and edema pattern would be helpful to distinguish breast cancer subtypes.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2012
    The importance of multifocal/multicentric tumor on the disease-free survival of breast cancer patients: Single center experience

    Ustaalioglu, Basak Oven; Bilici, Ahmet; Kefeli, Umut; Şeker, Mesut; Oncel, Mustafa; Gezen, Cem; Gumus, Mahmut; Demirelli, Fuat

    OBJECTIVES:: Multifocal/multicentric breast cancers have been comprehensively studied and their outcomes have been compared with unifocal tumors. We evaluated the impact of multifocality and multicentricity on the disease-free survival (DFS) and overall survival of breast cancer patients and tried to analyze the correlation between multifocality/multicentricity (M/M) and other prognostic factors. MATERIAL AND METHODS:: Between 1994 and 2009, we analyzed retrospectively 697 breast cancer patients. Multicentric and multifocal breast cancer were defined as the presence of 2 or more invasive tumor foci within the different quadrants of the same breast or within a same quadrant of the breast, respectively. M/M and other prognostic factors were evaluated using univariate and multivariate analyses. RESULTS:: Multifocal/multicentric tumors were seen in 107 (15.4%) of the 697 breast cancer patients. pT and pN stage were related with the presence of multifocal/multicentric tumors. As tumor size increased and the number of axillary lymph nodes metastasis increased, the incidence of M/M increased significantly (P=0.003 vs. P=0.02, respectively). Overall, the median DFS time of patients with multifocal/multicentric tumors was significantly worse than that of the unifocal tumors (55 vs. 137 mo, P<0.001). Multivariate analysis showed that the presence of M/M was the most important prognostic factor for DFS (P=0.001, hazard ratio (HR): 0.33; 95% confidence interval (CI), 0.18-0.58), as were pN stage and extracapsular extension of the tumor (P=0.01, HR: 1.74; 95% CI, 1.13-2.69) (P=0.03, HR: 1.9; 95% CI, 1.04-3.47, respectively). M/M were not also statistically significant prognostic factors in breast cancer for overall survival (P=0.06). CONCLUSIONS:: M/M imparts an unfavorable prognosis on the DFS of breast cancer patients in comparison to unifocal tumors and the presence of multifocal/multicentric tumors were associated with advanced pT and pN stages.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2010
    Does the metastatic lymph node ratio influence the disease-free survival of patients with breast cancer: Single-center experiences

    Oven Ustaalioglu, Bala Basak; Bilici, Ahmet; Kefeli, Umut; Şeker, Mesut; Yildirim, Emre; Salepci, Taflan; Oncel, Mustafa; Kement, Metin; Gumus, Mahmut

    Background: Axillary lymph nodes (ALNs) are the most important prognostic factor for survival in breast cancer. Pathological evaluation can affect the number of involved lymph nodes. In the current study, we evaluated whether the metastatic lymph node ratio (n ratio) is important in predicting disease-free survival (DFS) for breast cancer patients. Material and Methods: From 802 breast cancer cases, 427 patients with ALN metastasis were analyzed retrospectively. The n ratio was categorized as n ratio 1 (1-10%), n ratio 2 (10.01-50%) and n ratio 3 (>50%). DFS was established according to the Kaplan-Meier method. Predicting risk factors for relapse were analyzed using the Cox proportional hazards model. Results: The n ratio was significantly higher in breast cancer patients with advanced pathologic pT, pN and clinical stage, undifferentiated histology, lymphovascular and extracapsular invasion, more resected ALNs and positive progesterone receptor. In the univariate analysis, multicentricity, necrosis, grade, pN stage, estrogen receptor and progesterone receptor positivity, trastuzumab and neoadjuvant chemotherapy usage, the presence of inflammatory breast cancer and n ratio were found to be important factors in predicting DFS. Multivariate analysis indicated that multicentricity, neoadjuvant chemotherapy, trastuzumab usage and n ratio were significantly associated with prognosis. Conclusions: The n ratio is inexpensive, easily available and a simple prognostic factor for breast cancer patients with positive ALNs.

    • SDG 3 · Sağlık ve Kaliteli Yaşam