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- MakaleAçık Erişim2024Scopus SJRQ2Investigation of Antibiofilm and Antibacterial Properties of Green Synthesized Silver Nanoparticles from Aqueous Extract of Rumex sp.
Akay, Seref; Yüksel, Gamze; Özad Düzgün, Azer
The decrease in the effectiveness of conventional drugs as a result of the growth of resistance to antibiotics has increased the need for innovative tools to control the infections. At this point, metallic nanoparticles, in particular silver nanoparticles, have appeared as a promising method. In the current study, the extract of Rumex sp. (Labada, dock) leaves was used as a reducing agent for the formation of silver nanoparticles. Unlike similar studies, in this study the synthesis conditions were optimized by changing the extract ratio and silver nitrate concentration. Morphological investigations of synthesized silver nanoparticles showed that spherical homogeneous particles at size under 100 nm had been produced. SEM/EDS and FTIR analyses showed that plant components are involved in the synthesis of nanoparticles. It was also determined that higher extract ratio reduced nanoparticle size. The antimicrobial effects of the synthesized nanoparticles against Gram-positive and Gram-negative bacteria were tested, and it was determined that all nanoparticles exhibited activity against both groups. Rumex sp. silver nanoparticles (NPs) were revealed to exhibit antibiofilm activity against three different isolates with moderate and strong biofilm-forming ability. The NPs reduced the biofilm-forming capacity of Acinetobacter baumannii and Klebsiella pneumonaie by 2.66-fold and 3.25-fold, whereas they decreased the Escherichia coli biofilm-forming capacity by 1.25-fold. The investigation of microbial biofilm could play an important role in developing new strategies for treatment options. Our results suggest that Rumex sp. silver NPs may have a high potential for use in the treatment of pathogenic strains.
AtıfScopus8WoS7OpenAlex7İncele - MakaleAçık Erişim2021Scopus SJRQ3Investigation of the removal of sulfamethoxazole drug waste from aqueous solutions under the effect of zinc oxide/montmorillonite nanocomposite by photocatalytic ozonation process
Özyürek, Işıl Nihan; Kıranşan, Murat; Karaca, Semra
In this study, the synergistic effect of photocatalysis and ozonation processes to degrade the sulfamethoxazole (SMX), one antibiotic pharmaceutical compound, has been studied through the influence of main operational variables such as zinc oxide/montmorillonite (ZnO/MMT) dos-age, SMX initial concentration, ozone flow rate, pH and the addition of organic and inorganic scavengers. Synthesized ZnO nanoparticles were immobilized on the montmorillonite surface to prepare ZnO/MMT catalyst as a photocatalyst. The catalyst was characterized by X-ray fluo-rescence, X-ray diffraction, scanning electron microscope, high-resolution transmission electron microscope and N2 adsorption/desorption. The highest SMX degradation efficiency (80.84% for 30 min of reaction time) was obtained for the photocatalytic ozonation process compared to adsorption, single ozonation, catalytic ozonation, and photolysis. ZnO/MMT was more effective photocatalyst according to ZnO, indicating its usability as a promising photocatalyst for the removal of organic contaminants in aqueous solutions. The reduced degradation efficiency with the addition of organic and inorganic scavengers showed the important role of the photo-produced radicals and holes as well as direct ozonation in SMX degradation. A mechanism is also proposed for photocatalytic ozonation degradation by using the gas chromatography-mass spectroscopy (GC-MS) analysis method. Finally, several by-products were identified by GC-MS analysis, which allowed to depict a possible mechanism for the sulfamethoxazole degradation.
AtıfScopus9WoS7OpenAlex10İncele