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- MakaleYalnız künye2025Spontaneous Retroperitoneal Hemorrhage withPsoasHematoma i n anElderlyPatient: ADiagnostic and Therapeutic Challenge
Eyüboglu, Kayahan; Keskin, Cem
Spontaneous retroperitoneal hemorrhage (SRH) is a rare and potentially life-threatening condition, often challenging to diagnose and manage, especially in elderly patients with multiple comorbidities. Psoas hematoma is a known complication that can be associated with anticoagulation therapy. A 93-year-old male patient with a history of atrial fibrillation, chronic heartfailure, and anticoagulant use (apixaban) presented with complaints of dizziness following a fall in the bathroom. He was initially assessed in the neurology clinic for potential cognitive symptoms; however, while awaiting assessment, he experienced a syncopal episode, resulting in his transfer to the emergency room. The patient had a significant reduction in hemoglobin levels, necessitating additional examination. Imaging revealed an 8 cm left psoas hematoma with active extravasation. The patient received a blood transfusion, vitamin K, and therapeutic interventions, including interventional radiology, which effectively halted the hemorrhage. This case highlights the diagnostic complexity and therapeutic challenges posed by spontaneous retroperitoneal hemorrhage in elderly patients, especially those on anticoagulant therapy. Early recognition and appropriate intervention are crucial for patient recovery.
- MakaleAçık Erişim2020The Ameliorative Effects of Ethyl Pyruvate and Dimethyl Sulfoxide on Ischemic Tissue Injury in Experimental Carbon Monoxide Intoxication
Pasli, Sinan; Imamoglu, Melih; Çiçek, Mustafa; Yadigaroglu, Metin; Sahin, Aynur; Karaca, Yunus; Yulug, Esin; Tatli, Ozgur
Aim: The purpose of this study was to investigate the protective effects of ethyl pyruvate (EP) and dimethyl sulfoxide (DMSO) on ischemic tissue in brain and cardiac and hepatic tissues in experimentally induced carbon monoxide (CO) intoxication. Material and Methods: Thirty-five mature female Sprague Dawley rats were randomized into five groups of seven animals each. Group 1 received no CO or treatment. Rats in groups 2, 3, 4 and 5 were made to inhale a high-concentration 5000 ppm CO gas mixture for 60 min at 4 L/min. CO levels were then measured from 1 mL tail vein blood. Group 2 received no therapeutic agent, group 3 received 6 mg/kg intraperitoneal (ip) DMSO, group 4 received 50 mg/kg ip EP, group 5 received 50 mg/kg EP and 6 mg/kg DMSO ip. All rats were sacrificed by decapitation. Brain, cardiac and hepatic tissues were removed and histopathological scores were compared. Results: Comparison of group 2 with group 3 and group 2 with group 5 revealed that DMSO alone and EP + DMSO exhibited a reducing effect on degree of cerebral neuronal alteration, degenerative neuron rates, and total cardiac injury score (p=0.005, p=0.002, p=0.004 and p=0.002, p=0.001, p=0.004 respectively). There was no histopathological difference between group 2 and group 4 suggesting EP alone had no therapeutic effect on histopathological injury. Conclusion: Based on our study findings, EP administered alone exhibited no protective effects on the organ injuries investigated, while DMSO exhibited reducing effects on degree of neuron alteration, rates of degenerative neurons, and total cardiac injury scores. An ameliorating effect on cardiac and hepatic injury was more prominent with combined treatment.
- MakaleAçık Erişim2017Nutmeg Intoxication Associated with Consumption as a Stupefacient
Günaydin, Mucahit; Tatli, Ozgur; Altuntas, Gurkan; Uslu, Zakire; Özsahin, Faruk; Beslioglu, Necla
Introduction: Nutmeg is the dried seed of an evergreen aromatic tree from the plant family Myristicaceae. It is widely used in traditional medicine. Although misuse is rare, it needs to be understood that this plant, widely used as a spice in various parts of the world, can be misused and can result in emergency presentation due to intoxication. Case Report: We describe a case of intoxication in a 22-year-old male student after he mixed nutmeg with fruit juice and drank it. Neurological symptoms and anticholinergic signs were present during presentation. Conclusion: Nutmeg intoxication must be one of the possibilities considered at differential diagnosis in patients presenting to the emergency department with findings of anticholinergic intoxication.
- DergiJOURNAL OF EMERGENCY MEDICINE CASE REPORTS