Determination of Antioxidant Capacity of 2,6-Quinolinediol

The compounds of the quinolone group have been widely used in the alive metabolism,paint and pharmaceutical industry. Therefore, various quinoline derivatives are synthesized andsynthesis methods are developed. The synthesis of the quinoline compounds in the industrial field isformed in a separate area. 2,6-quinolinediol is derivative a quinoline. In this study, differentbioanalytical methods such as reducing capacity by Fe3+-Fe2+ transformation method, Fe3+-TPTZreducing capacity by FRAP method, Cu2+-Cu+reducing capacity by CUPRAC method, the ferric ions(Fe2+) chelating activity by using bipyridyl reagent, DPPH, ABTS, DMPD radical scavengingactivities, superoxide anion radicals (O2.-) scavenging activity have been used. Also, Trolox, αTocopherol, BHA and BHT have been used as reference antioxidants. The IC50 inhibition value of theABTS radical removal activity for this substance was calculated as 3.39 µg mL-1. Referenceantioxidants such as trolox, BHA, α-Tocopherol and BHT exhibited ABTS radical removal inhibitionsat 2.59, 4.44, 7.07 and 32.36 µg mL-1, respectively. Studies have shown that 2,6-quinolinediol is aneffective antioxidant.