Exploring the Impacts of Angelica purpurascens Extracts on Anticholinergic, Antidiabetic, Antibacterial Potential, and Antioxidant Capacity

MakaleAçık Erişim
  • SDG 3 · Sağlık ve Kaliteli Yaşam

Özet

In Kars-Sarıkamış-Soğanlı, Angelica purpurascens (A. purpurascens) emerges as a promising natural antioxidant source. Extracts from its leaves, branches, and flowers underwent thorough bioanalytical assessments. The leaf extract exhibited the highest concentrations of herbal flavonoids (45.22 µg QE/mg extract) and total phenolics (28.96 µg GAE/mg extract). Branch extracts demonstrated significant enzymatic activity against AChE and BChE with IC50 values of 37.26 mg/mL and 9.08 mg/mL respectively. The flower extract displayed notable antibacterial properties. This study sheds light on the therapeutic potential of A. purpurascens ethanol extracts, suggesting benefits for Alzheimer’s, cell damage-induced diseases, and diabetes mellitus. It pioneers new enzymatic and antioxidant insights and contributes to understanding this abundant Türkiye species. A. purpurascens holds promise for pharmaceutical exploration, offering potential solutions for challenging health conditions.

Anahtar Kelimeler

RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/gumushane/12533Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.21597/jist.1411501Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorTopal, Meryem
dc.contributor.authorTopal, Fevzi
dc.contributor.authorYilmaz, Fırat
dc.date.accessioned2026-10-22T10:20:13.806390267Z
dc.date.available2026-10-22T10:20:13.806390267Z
dc.date.issued2024
dc.description.abstractIn Kars-Sarıkamış-Soğanlı, Angelica purpurascens (A. purpurascens) emerges as a promising natural antioxidant source. Extracts from its leaves, branches, and flowers underwent thorough bioanalytical assessments. The leaf extract exhibited the highest concentrations of herbal flavonoids (45.22 µg QE/mg extract) and total phenolics (28.96 µg GAE/mg extract). Branch extracts demonstrated significant enzymatic activity against AChE and BChE with IC50 values of 37.26 mg/mL and 9.08 mg/mL respectively. The flower extract displayed notable antibacterial properties. This study sheds light on the therapeutic potential of A. purpurascens ethanol extracts, suggesting benefits for Alzheimer’s, cell damage-induced diseases, and diabetes mellitus. It pioneers new enzymatic and antioxidant insights and contributes to understanding this abundant Türkiye species. A. purpurascens holds promise for pharmaceutical exploration, offering potential solutions for challenging health conditions.
dc.description.sponsorshipGümüşhane Üniversitesi, GU, (22.B0225.02.01)
dc.description.sponsorshipGümüşhane Üniversitesi, GU
dc.identifier.doi10.21597/jist.1411501
dc.identifier.eissn2536-4618
dc.identifier.endpage804
dc.identifier.issn2536-4618
dc.identifier.issue2
dc.identifier.scopus2-s2.0-105048447535
dc.identifier.startpage790
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/gumushane/12533
dc.identifier.volume14
dc.language.isoen
dc.publisherIğdır University
dc.relation.ispartofJournal of the Institute of Science and Technology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAlzheimer’s disease
dc.subjectAngelica purpurascens
dc.subjectAntibacterial
dc.subjectAntioxidant
dc.subjectCholinesterase
dc.subjectα-Glycosidase
dc.titleExploring the Impacts of Angelica purpurascens Extracts on Anticholinergic, Antidiabetic, Antibacterial Potential, and Antioxidant Capacity
dc.typeArticle
dspace.entity.typePublication
rdl.citation.openalex3
rdl.citation.scopus1
rdl.citation.trdizin2
rdl.oa.statusbronze
rdl.oa.urlhttps://dergipark.org.tr/en/download/article-file/3627236
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexTRDIZIN