A multi-stage fusion deep learning framework merging local patterns with attention-driven contextual dependencies for cancer detection

MakaleAçık Erişim
  • SDG 3 · Sağlık ve Kaliteli Yaşam

Özet

Cancer is a severe threat to public health. Early diagnosis of disease is critical, but the lack of experts in this field, the personal assessment process, the clinical workload, and the high level of similarity in disease classes make it difficult. In recent years, deep learning-based artificial intelligence models have shown promise, with the potential to increase diagnosis speed and accuracy. These models attract attention with their automatic learning and adaptation capabilities. In this study, the deep learning-based PADBSRNet model and the PADBSRNet-Vision Transformer (ViT) hybrid method are proposed for the detection of brain tumors and skin and lung cancers. PADBSRNet is a comprehensive deep neural network architecture that integrates separable and traditional convolution layers, multiple attention mechanisms, bidirectional recurrent neural networks, and cross-connections/multi-stage feature fusion strategies. This architecture offers significant advantages in terms of effectively extracting local-global, contextual features and accurately modeling long-term dependencies in image classification tasks. The second proposed approach developed a hybrid method that combines the advantages of the PADBSRNet model and the ViT model. Experimental analysis on medical datasets such as the Figshare Brain Tumor Dataset, IQ-OTH/NCCD Dataset, and Skin Cancer: Malignant vs. Benign Dataset has evaluated the proposed models' performances. According to the experimental results, the PADBSRNet model has shown successful performance with 95.24 %, 99.55 %, and 88.61 % accuracy rates, respectively. The experimental findings show that the proposed deep learning model can effectively learn the complex relationships and hidden patterns of cancer disease, thus producing applicable and effective results in cancer diagnosis.

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Tam Kayıt
AlanDeğerDil
dc.contributor.authorCatal Reis, Hatice
dc.contributor.authorTurk, Veysel
dc.date.accessioned2026-10-22T10:20:04.040723637Z
dc.date.available2026-10-22T10:20:04.040723637Z
dc.date.issued2025
dc.description.abstractCancer is a severe threat to public health. Early diagnosis of disease is critical, but the lack of experts in this field, the personal assessment process, the clinical workload, and the high level of similarity in disease classes make it difficult. In recent years, deep learning-based artificial intelligence models have shown promise, with the potential to increase diagnosis speed and accuracy. These models attract attention with their automatic learning and adaptation capabilities. In this study, the deep learning-based PADBSRNet model and the PADBSRNet-Vision Transformer (ViT) hybrid method are proposed for the detection of brain tumors and skin and lung cancers. PADBSRNet is a comprehensive deep neural network architecture that integrates separable and traditional convolution layers, multiple attention mechanisms, bidirectional recurrent neural networks, and cross-connections/multi-stage feature fusion strategies. This architecture offers significant advantages in terms of effectively extracting local-global, contextual features and accurately modeling long-term dependencies in image classification tasks. The second proposed approach developed a hybrid method that combines the advantages of the PADBSRNet model and the ViT model. Experimental analysis on medical datasets such as the Figshare Brain Tumor Dataset, IQ-OTH/NCCD Dataset, and Skin Cancer: Malignant vs. Benign Dataset has evaluated the proposed models' performances. According to the experimental results, the PADBSRNet model has shown successful performance with 95.24 %, 99.55 %, and 88.61 % accuracy rates, respectively. The experimental findings show that the proposed deep learning model can effectively learn the complex relationships and hidden patterns of cancer disease, thus producing applicable and effective results in cancer diagnosis.
dc.identifier.articlenumber109916
dc.identifier.doi10.1016/j.compbiomed.2025.109916
dc.identifier.issn0010-4825
dc.identifier.pmid40054172
dc.identifier.scopus2-s2.0-85219497579
dc.identifier.startpage109916
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/gumushane/12403
dc.identifier.volume189
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofComputers in Biology and Medicine
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAttention mechanism
dc.subjectCancer detection
dc.subjectConvolutional neural network
dc.subjectDeep learning
dc.subjectImage processing
dc.subjectMedical image classification
dc.subjectMulti-stage feature fusion
dc.subjectPattern recognition
dc.subject.otherBrain Neoplasms
dc.subject.otherDeep Learning
dc.subject.otherHumans
dc.subject.otherImage Interpretation, Computer-Assisted
dc.subject.otherLung Neoplasms
dc.subject.otherNeoplasms
dc.subject.otherNeural Networks, Computer
dc.subject.otherSkin Neoplasms
dc.subject.otherConvolutional neural networks
dc.subject.otherAttention mechanisms
dc.subject.otherCancer detection
dc.subject.otherConvolutional neural network
dc.subject.otherFeatures fusions
dc.subject.otherImages processing
dc.subject.otherMedical image classification
dc.subject.otherMulti-stage feature fusion
dc.subject.otherMulti-stages
dc.subject.otherStages features
dc.subject.otherArticle
dc.subject.otherartificial intelligence
dc.subject.otherbrain tumor
dc.subject.othercancer diagnosis
dc.subject.othercolorectal cancer
dc.subject.otherdecision tree
dc.subject.otherdeep neural network
dc.subject.otherdiagnostic accuracy
dc.subject.otherearly cancer diagnosis
dc.subject.otherfeature extraction
dc.subject.otherglioma
dc.subject.otherhuman
dc.subject.otherhypophysis tumor
dc.subject.otherimage analysis
dc.subject.otherimage processing
dc.subject.otherlarge cell carcinoma
dc.subject.otherlung adenocarcinoma
dc.subject.otherlung nodule
dc.subject.othermajor clinical study
dc.subject.othermalignant neoplasm
dc.subject.othermeningioma
dc.subject.othernuclear magnetic resonance imaging
dc.subject.otherpattern recognition
dc.subject.otherrecurrent neural network
dc.subject.otherskin cancer
dc.subject.othersquamous cell lung carcinoma
dc.subject.othersupport vector machine
dc.subject.otherthorax radiography
dc.subject.otherartificial neural network
dc.subject.othercomputer assisted diagnosis
dc.subject.otherdiagnostic imaging
dc.subject.otherlung tumor
dc.subject.otherneoplasm
dc.subject.otherprocedures
dc.subject.otherskin tumor
dc.subject.otherLung cancer
dc.titleA multi-stage fusion deep learning framework merging local patterns with attention-driven contextual dependencies for cancer detection
dc.typeArticle
dspace.entity.typePublication
rdl.citation.openalex2
rdl.citation.scopus3
rdl.departmentDepartment of Geomatics Engineering, Gumushane University, Gumushane, 29000, Turkey
rdl.oa.statusgreen
rdl.oa.urlhttps://hdl.handle.net/20.500.12440/6472
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexPUBMED