Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Bayrakdaroglu, Serdar(2)
- Bilici, Ahmet(2)
- Ceylan, Halil Ibrahim(2)
- Gezen, Cem(2)
- Gumus, Mahmut(2)
- Oncel, Mustafa(2)
- Stefanica, Valentina(2)
- Akan, Mithat(1)
- Akay, Yasar(1)
- Aksan, Tolga(1)
- Altuntas, Yunus E.(1)
- Anik, Ihsan(1)
- Arik, Osman Z.(1)
- Askeroglu, Ufuk(1)
- Basat, Salih Onur(1)
- Bozkurt, Mehmet(1)
- Cabuk, Burak(1)
- Cakir, Ozgur(1)
- Caklili, Melih(1)
- Caliskan Atac, Damla(1)
- Can, Ibrahim(1)
- Celik, Evrim Coskun(1)
- Ceran, Fatih(1)
- Ceylan, Savas(1)
- Ciftci, Ercument(1)
- Demirelli, Fuat(1)
- Dhahbi, Wissem(1)
- Elbasan, Zafer(1)
- Emengen, Atakan(1)
- Emre, Ender(1)
- Epçeliden, Tuncay(1)
- Erel, Ozcan(1)
- Ergen, Anil(1)
- Erhan, Belgin(1)
- Ertas, Gokhan(1)
- Gokbel, Aykut(1)
- Gunduz, Berrin(1)
- Gözükara, Mehmet Y.(1)
- Günay, Ahmet Rahmi(1)
- Gür, Mustafa(1)
Yayınlar
- MakaleAçık Erişim2026Multi-joint isokinetic strength profiling as a predictor of vertical jump performance in elite freestyle wrestlers A cross-sectional principal component analysis
Sever, Ozan; Ceylan, Halil Ibrahim; Dhahbi, Wissem; Yilmaz, Hasan Huseyin; Özdemir, Kubra; Yazici, Ahmet Gokhan; Jalalov, Ferhad; Günay, Ahmet Rahmi; Bayrakdaroglu, Serdar; Stefanica, Valentina
Wrestling requires coordinated lower-limb strength for explosive techniques. While isokinetic testing isolates joint-specific strength and countermovement jumps assess functional power, comprehensive multi-joint assessments with advanced factor analysis remain unexplored in elite wrestlers. Twenty-one national-level male freestyle wrestlers (22.3 +/- 2.8 years; 76.2 +/- 14.7 kg) completed cross-sectional neuromuscular assessments. Isokinetic concentric strength testing at 60 degrees/s evaluated hip, knee, and ankle joint functions bilaterally using an Isomed 2000 dynamometer. Vertical jump power was assessed through countermovement jumps under bilateral and unilateral conditions using the Optojump system. All strength and power variables were normalized to fat-free mass determined via air displacement plethysmography. Statistical analyses included Pearson correlations with Benjamini-Hochberg correction, stepwise multiple regression, and principal component analysis. Bilateral jump performance correlated strongly with knee extension (R = 0.798, P <.001) and hip extension strength (R = 0.664, P =.001), with combined predictors explaining 68.8% of variance (F-2,F-18 = 19.8, P <.001). Principal component analysis identified a primary extensor factor (hip and knee extension, 52.6% variance) and an auxiliary factor (ankle plantar flexion and hip adduction, 19.0% variance). Unilateral jump models demonstrated lower explanatory power (dominant: 39.8%, non-dominant: 25.7%). Multi-joint isokinetic strength assessment, particularly hip and knee extension capacity, provides a robust prediction of vertical jump performance in elite wrestlers. The identified primary extensor strength factor represents a fundamental neuromuscular capacity underlying explosive lower-limb function, supporting targeted strength development strategies for wrestling-specific performance enhancement.
- MakaleAçık Erişim2025Management of Major Arterial Injuries: A Critical Complication of Endoscopic Endonasal Surgery
Emengen, Atakan; Yilmaz, Eren; Gokbel, Aykut; Uzuner, Ayse; Cakir, Ozgur; Ciftci, Ercument; Ozsoy, Bedrettin; Ergen, Anil; Caklili, Melih; Cabuk, Burak
BACKGROUND AND OBJECTIVES:Endoscopic endonasal surgery (EES) is the preferred approach for treating sellar and parasellar lesions due to its panoramic view and detailed anatomical definition. This study aims to review major arterial injuries during EES, a rare but critical complication associated with high mortality and morbidity rates.METHODS:A retrospective analysis was conducted, including 15 patients from 5640 EES procedures performed between August 1997 and February 2024 at in our center/Department of Neurosurgery. The study focuses on perioperative and postoperative management strategies, highlighting the use of oxidized regenerated cellulose (Surgicel (R))/gelatin-thrombin matrix (Floseal (R)) and multidisciplinary collaboration to achieve hemostasis.RESULTS:The incidence of major arterial injury was 0.2%, with a mean patient age of 38.4 years and a female-to-male ratio of 10:5. The most common tumors were adenomas (n = 7) and chordomas (n = 5). The most commonly bleeding arteries in 6 patients each are the cavernous segment of the internal carotid artery and the paraclival carotid artery. Low-flow bleeding was observed in 10 of our patients, while high-flow bleeding was seen in 5 patients, 4 of whom were recurrent cases (P < .05). In 3 patients with high-flow bleeding from segments of the carotid artery, digital subtraction angiography was performed for stent placement or coil embolization, while in 1 patient with high-flow bleeding, digital subtraction angiography was used for monitoring cerebral blood flow. One of our patients died of a myocardial infarction at the 14th month of follow-up and 1 of our patients developed left-hemiparesis.CONCLUSION:The study underscores the importance of preoperative planning, surgical expertise, and multidisciplinary teamwork in managing major arterial injuries during EES. The authors advocate for the development of standardized treatment algorithms to improve outcomes in these patients. The findings contribute to the limited literature on managing internal carotid artery injuries in EES, emphasizing the need for ongoing research and algorithm development.
- MakaleAçık Erişim2025Recurrent aphthous stomatitis, oxidative stress, and ischemia modified albumin: A cross-sectional study
Öztekin, Aynure; Öztekin, Coskun; Sahin, Humeyra Nursel; Karadeniz, Tuba Betul; Senel, Engin; Caliskan Atac, Damla; Savci, Unsal; Neselioglu, Salim; Erel, Ozcan
Recurrent aphthous stomatitis is an inflammatory disease characterized by painful ulcers on the oral mucosa. Oxidative stress is held responsible for the pathogenesis of this disease of unknown etiology. In oxidative stress, the balance between oxidant-antioxidant substances changes in favor of the oxidative side. Ischaemia modified albumin (IMA) is a new type of albumin. It occurs as a result of factors such as ischemic attacks and oxidative stress. The aim of the study was to compare IMA levels in patients with recurrent aphthous stomatitis with healthy volunteers and to investigate whether IMA has a diagnostic value in the disease. This cross-sectional study included 32 patients with recurrent aphthous stomatitis and 34 healthy volunteers of similar age and sex. Albumin and IMA levels were determined by spectrophotometric albumin cobalt binding assay in venous blood samples on the same day. IMA was expressed as absorbance unit. Receiver operating characteristic analysis was used to determine whether IMA values could be a diagnostic marker for prediction of disease. IMA values of the patient group were significantly higher than IMA values of the control group (P < .001). IMA was statistically significant in the prediction of recurrent aphthous stomatitis (P < .001). The discrimination power for IMA was very good (area under the receiver operating characteristic curve 95% CI = 0.952 [0.897-1.000]). Recurrent aphthous stomatitis, in which oxidative stress plays a role in the etiopathogenesis, is closely associated with high IMA levels. IMA levels may have diagnostic value as an indicator of oxidative stress in the disease.
- MakaleAçık Erişim2025Exploring the acute recovery effects of dry cupping therapy and electrical stimulation on anaerobic performance metrics in active individuals: A quasi-experimental crossover study
Can, Ibrahim; Yerlikaya, Gokhan; Yalçin, Seda; Bayrakdaroglu, Serdar; Kayhan, Recep Fatih; Uluç, Ender Ali; Stefanica, Valentina; Ceylan, Halil Ibrahim
Background:This quasi-experimental crossover study aimed to examine the acute effects of dry cupping therapy (DCT) and neuromuscular electrical stimulation (NMES) on fatigue and perceived exertion in anaerobic performance among physically active individuals.Methods:Twelve male participants (mean age: 24.1 +/- 2.37 years), all students from the Faculty of Sports Sciences, were recruited to participate voluntarily. Anaerobic performance parameters, including peak power, mean power (MP), and fatigue index (FI), were assessed using a Monark 839E cycling ergometer under 3 distinct conditions: NMES, DCT, and a control condition (no intervention), with each session separated by a 48-hour rest period. Perceived exertion was evaluated immediately following each test session using Borg's rate of perceived exertion (RPE) scale. Both NMES and DCT were administered bilaterally to the hamstring (m. hamstring) and quadriceps femoris (m. quadriceps femoris) muscles for 20 minutes before testing.Results:The results revealed no statistically significant differences in peak power and MP across the conditions. However, significant effects were identified for FI (F(2, 22) = 4.08, P = .031, eta p(2) = 0.27) and RPE (F(2, 22] = 8.88, P = .0015, eta p(2) = 0.45). Post hoc pairwise comparisons indicated that NMES significantly reduced FI compared to the control condition (P = .0311), with a small to medium effect size (Cohen's d = 0.44). In terms of RPE, DCT significantly lowered values compared to both the control (P = .0018) and NMES conditions (P = .0005), demonstrating medium (Cohen's d = 0.74) and small to medium (Cohen's d = 0.37) effect sizes, respectively.Conclusions:While NMES and DCT did not elicit acute improvements in peak or mean anaerobic power, both interventions effectively mitigated fatigue and reduced perceived exertion during maximal anaerobic exercise. These findings suggest that NMES and DCT may serve as valuable recovery modalities for mitigating fatigue in sports characterized by high anaerobic demands. Future research should investigate the chronic effects of these interventions and explore their utility among trained athletes to determine their broader applicability in enhancing athletic performance.
- MakaleYalnız künye2016Preventing Suture Extrusion and Recurrence in Mustarde and Furnas Otoplasties by Using Laterally Based Postauricular Dermal Flap, Long-Term Results
Basat, Salih Onur; Ceran, Fatih; Askeroglu, Ufuk; Aksan, Tolga; Orman, Cagdas; Yazar, Memet; Uscetin, Ilker; Akan, Mithat; Bozkurt, Mehmet
Background:Prominent ear deformity (PD) is an unacceptable condition of pinna that affects 5% of the population and is associated with emotional stress, behavioral disturbances, and social restrictions in relationships. Conchal hypertrphy, inadequate formation of antihelical fold, earlobe placement ahead than it should be, or various combinations of these changes are main characteristics of PD. Many surgical techniques have been described for the PD.The authors' aim was to present laterally based postauricular dermal flap combination with cartilage-sparing methods and effectiveness of this technique in suture extrusion prevention and reducing the rate of recurrence with long-term results.Methods:Forty-one patients had bilateral and 6 patients had unilateral PD, a total of 47 patients with a mean age of 14.48 were operated by using this combined procedure. A laterally based supraperichondrial dermal flap was prepared from a deepithelized elliptical postauricular incision. Mustarde and Furnas suture techniques were used solely for PD correction. The dissected laterally based dermal flap was fixed to the mastoid bone with sutures in stretched position after reshaping the auricular cartilage with sutures.Results:The average helix-mastoid distance was (mm) 16.282.36, concha-mastoid angle was 25.71 +/- 0.96 degrees on 12-month measurements. The helix-mastoid distance showed an increase of 1 to 3mm, in the concha-mastoid angle measurements of 1 degrees to 2 degrees. Statistically significant changes were observed between the average preoperative, postoperative 1. month, postoperative 12. month helix-mastoid distances (mm), and month concha-mastoid angle (degrees) measurements (P=0.0001).Conclusions:The laterally based postauricular dermal flap technique is an effective method to prevent suture extrusion and recurrence which are the most important complications of otoplasty procedure and easy to apply.
- MakaleYalnız künye2016Mean platelet volume is related with ischemic stroke in patients with sinus rhythm
Özkan, Bugra; Arik, Osman Z.; Gözükara, Mehmet Y.; Sahin, Durmus Y.; Topal, Salih; Uysal, Onur K.; Elbasan, Zafer; Epçeliden, Tuncay; Çayil, Murat; Gür, Mustafa
Stroke is the leading cause of disability worldwide. It is known that atrial fibrillation and left atrial enlargement contribute ischemic stroke, and mean platelet volume (MPV) increases in patients with ischemic stroke and atrial fibrillation. We aimed to determine whether higher MPV is associated with ischemic stroke in patients with sinus rhythm. We evaluated 74 patients in sinus rhythm and with ischemic stroke (Group 1) and 90 age-matched and sex-matched healthy individuals as control group (Group 2). After physical and echocardiographic examination, 24-48 h Holter monitoring and complete blood counts were studied. There were no statistically significant differences in age, sex rates, and comorbidities between groups. Left atrial diameter was higher in Group 1 than Group 2 (P=0.001), but both were in normal range. MPV was significantly higher in Group 1 (P<0.001) and was an independent determinant [odds ratio (OR): 1.840; P<0.001; 95% confidence interval (CI) 1.330-2.545] of ischemic stroke with left atrial (OR: 1.138; P=0.006; 95% CI 1.037-1.248). In conclusion, higher MPV is associated with acute ischemic stroke in patients with sinus rhythm and without heart failure or left atrial enlargement. MPV and left atrial diameter are independent predictors of ischemic stroke in this patient population. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
- MakaleYalnız künye2012Effect of enhanced external counterpulsation treatment on mean platelet volume in patients affected by ischemic chronic heart failure
Ertas, Gokhan; Kozdag, Guliz; Emre, Ender; Akay, Yasar; Ural, Dilek; Hebert, Kathy
Mean platelet volume (MPV) is increased in chronic heart failure (CHF) and is an independent predictor of mortality in CHF patients. It is not known whether enhanced external counterpulsation (EECP) therapy leads to decreased MPV values or not. The purpose of this study was to examine the effects of EECP on platelet count and MPV values and to assess the influence of MPV on the risk of death and recurrent ischemic events in ischemic CHF patients. A total of 68 ischemic heart failure patients with CHF symptoms and refractory angina pectoris were included in the study, 47 consecutive patients (39 males and eight females) aged 44-82 years. Although follow-up period started after completion of EECP in treated patients, control group follow-up started at the end of 7-week treatment without EECP. All patients were monitored for a mean duration of 13 +/- 8 months (range, 1-36 months). The primary endpoints of the study were effects of EECP treatment on platelets after treatment period (7 weeks) and the recurrence of ischemic events. Secondary endpoint was cardiovascular death during the follow-up period. We observed a significant increase in platelet count and decrease in MPV levels (P=0.044 and P=0.004, respectively) in the control group. There were no significant differences in platelet count and MPV levels in the EECP group (P>0.05). After the treatment period, New York Heart Association functional classification (2.60 +/- 0.75 vs. 1.72 +/- 0.68, P<0.001) and Canadian Cardiovascular Society functional classification of angina (2.50 +/- 0.90 vs. 1.60 +/- 0.74, P<0.001) improved in patients with EECP treatment. In our study, we found that EECP therapy had a neutral effect on MPV values and platelet count Blood Coagul Fibrinolysis 23:127-131 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
- MakaleYalnız künye2012The importance of multifocal/multicentric tumor on the disease-free survival of breast cancer patients: Single center experience
Ustaalioglu, Basak Oven; Bilici, Ahmet; Kefeli, Umut; Şeker, Mesut; Oncel, Mustafa; Gezen, Cem; Gumus, Mahmut; Demirelli, Fuat
OBJECTIVES:: Multifocal/multicentric breast cancers have been comprehensively studied and their outcomes have been compared with unifocal tumors. We evaluated the impact of multifocality and multicentricity on the disease-free survival (DFS) and overall survival of breast cancer patients and tried to analyze the correlation between multifocality/multicentricity (M/M) and other prognostic factors. MATERIAL AND METHODS:: Between 1994 and 2009, we analyzed retrospectively 697 breast cancer patients. Multicentric and multifocal breast cancer were defined as the presence of 2 or more invasive tumor foci within the different quadrants of the same breast or within a same quadrant of the breast, respectively. M/M and other prognostic factors were evaluated using univariate and multivariate analyses. RESULTS:: Multifocal/multicentric tumors were seen in 107 (15.4%) of the 697 breast cancer patients. pT and pN stage were related with the presence of multifocal/multicentric tumors. As tumor size increased and the number of axillary lymph nodes metastasis increased, the incidence of M/M increased significantly (P=0.003 vs. P=0.02, respectively). Overall, the median DFS time of patients with multifocal/multicentric tumors was significantly worse than that of the unifocal tumors (55 vs. 137 mo, P<0.001). Multivariate analysis showed that the presence of M/M was the most important prognostic factor for DFS (P=0.001, hazard ratio (HR): 0.33; 95% confidence interval (CI), 0.18-0.58), as were pN stage and extracapsular extension of the tumor (P=0.01, HR: 1.74; 95% CI, 1.13-2.69) (P=0.03, HR: 1.9; 95% CI, 1.04-3.47, respectively). M/M were not also statistically significant prognostic factors in breast cancer for overall survival (P=0.06). CONCLUSIONS:: M/M imparts an unfavorable prognosis on the DFS of breast cancer patients in comparison to unifocal tumors and the presence of multifocal/multicentric tumors were associated with advanced pT and pN stages.
- MakaleYalnız künye2011Laparoscopic abdominoperineal resections for mid or low rectal adenocarcinomas: A retrospective, comparative study
Gezen, Cem; Altuntas, Yunus E.; Kement, Metin; Okkabaz, Nuri; Bilici, Ahmet; Vural, Selahattin; Gumus, Mahmut; Oncel, Mustafa
BACKGROUND: Laparoscopic abdominoperineal resection (APR) has been seldom studied apart from low anterior resections, and deserves to be separately analyzed. This study aims to compare perioperative and oncological outcomes of laparoscopic and conventional APRs performed for the treatment of mid and low rectal adenocarcinomas. MATERIALS AND METHODS: Patients operated for primary mid or low rectal adenocarcinoma between 2001 and 2009 in our institution were retrospectively investigated. These data were abstracted and compared within conventional and laparoscopic resection groups: demographics, tumor and procedure-related parameters, perioperative results, early oncological outcomes, and survival. RESULTS: Demographics and tumor and procedure-related parameters were similar within the laparoscopic (n=31) and conventional (n=36) groups, except intraoperative bleeding and requirement for transfusion, which were significantly lower after laparoscopic APRs. Perioperative results including complication, reoperation, and 30-day mortality rates were identical. Early oncological results and 3-year survival rates were alike. CONCLUSIONS: The perioperative results and oncological outcomes are similar after laparoscopic and conventional APRs. As current data include limited number of patients in a retrospective design, further studies comparing laparoscopic and conventional APR techniques are required.
- MakaleYalnız künye2009The Effect of Local Injections in Hemiplegic Shoulder Pain A Prospective, Randomized, Controlled Study
Lakse, Emre; Gunduz, Berrin; Erhan, Belgin; Celik, Evrim Coskun
Objective: The aim of this study was to evaluate the effects of corticosteroid injections on hemiplegic shoulder pain and range of motion. Design: Fifty-two stroke patients with shoulder pain were evaluated. Thirty-eight patients who fulfilled the criteria were assigned randomly into either injection or control groups. Transcutaneous electrical nerve stimulation and therapeutic exercise program were applied to both groups for 15 sessions. The patients in the injection group were administered either intra-articular or subacromial injections of corticosteroid and local anesthetic according to their pathology. The evaluations were performed before treatment and at the first and fourth weeks of treatment. Primary follow-up parameters were passive shoulder range of motion and verbal analog scale for shoulder pain; secondary follow-up parameters were modified Barthel index, Brunnstrom upper-extremity score, and modified Ashworth scale. Results: In both groups, shoulder range of motion and shoulder pain scores showed significant improvement. When the two groups were compared, the improvement was more significant in the injection group. Barthel scores improved in both groups, and no difference was found between the groups. Brunnstrom upper-extremity and modified Ashworth scores revealed nonsignificant changes in both groups. Conclusions: Adding corticosteroid injection to conventional treatment in hemiplegic shoulder pain improved shoulder range of motion and decreased pain scores before treatment to the first and fourth weeks of treatment. Injection in hemiplegic shoulder pain is recommended in appropriate patients.
- DergiOPERATIVE NEUROSURGERY
- DergiAMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
- DergiJOURNAL OF CRANIOFACIAL SURGERY
- DergiBLOOD COAGULATION & FIBRINOLYSIS
- DergiMEDICINE