Sürdürülebilir Kalkınma Amaçları
Yayınlar
- BildiriYalnız künye2025Investigation of antioxidant and antidiabetic activities of propolis obtained from different locations of artvin
Turan, I.; Gultekin, D. Canbolat; Akmese, O.; Gultekin, E.; Demir, S.; Aliyazicioglu, Y.
- BildiriYalnız künye2025Investigation of antioxidant and antidiabetic activities of different extracts of Vitis labrusca fruit peels
Güntekin, D. Canbolat; Akmese, O.; Gültekin, E.; Bak, F. Ersen; Özkan, A. I.; Turan, I.; Demir, S.; Aliyazicioglu, Y.
- BildiriYalnız künye2016Selective cytotoxic effect of Morus rubra extract in human lung cancer cells through enhancing apoptosis and cell cycle arrest
Turan, I.; Demir, S.; Kilinc, K.; Aliyazicioglu, Y.; Alver, A.; Misir, S.; Yaman, S. Ozer; Akbulut, K.; Deger, O.
- BildiriYalnız künye2016The epithelizan effect of the Morus nigra extracts on rats
Kilinç, K.; Turan, I.; Özgen, U.; Livaoglu, M.; Ural, A.; Sener, S. O.; Kara, H.; Efe, G.; Demir, S.
- BildiriYalnız künye2013THE ROLE OF OXIDATIVE STRESS IN CHILDREN WITH ACUTE AND CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA
Erduran, E.; Cakmak, S.; Aliyazicioglu, Y.; Turan, I.
- MakaleYalnız künye2011Preventive and protective effects of turkish propolis on H 2O 2-induced DNA damage in foreskin fibroblast cell lines
Aliyazicioglu, Yuksel; Demir, S.; Turan, I.; Cakiroglu, Tugba; Akalin, I.; Deger, O.; Bedir, A.
The aim of the present study was to evaluate the potential of Turkish propolis extracts if they prevent or protect foreskin fibroblast cells against hydrogen peroxide (H 2O 2)-induced oxidative DNA damage. Hydrogen peroxide (40 μM) was used as an inducer of oxidative DNA damage. The damage of DNA was evaluated by using the alkaline single cell gel electrophoresis (comet) assay. Turkish propolis extracts at concentrations of 25, 50, 75 and 100 μg/ml were prepared by ethanol. Anti-genotoxicity was assessed before, simultaneously, and after treatment of propolis extract (50 μg/ml) with H 2O 2. The results showed a significant decrease in H 2O 2-induced DNA damage in cultures treated with propolis extract. The antioxidant activity of phenolic components found in propolis may contribute to reduce the DNA damage induced by H 2O 2. Our findings confirmed the chemopreventive activity of propolis and showed that this effect may occur under different mechanisms.