Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2025Effects of hawthorn (Crataegus oxycantha) fruit extract on tibia bone properties in broiler chickens subjected to heat stress
Kaya, H.; Karaalp, M.
The purpose of this study was to examine the effects on tibia morphology, biomechanics, and mineral levels of varying dosages of hawthorn (Crataegus oxyacantha) fruit extract (HFE) addition to experimentally heat-stressed broiler drinking water. A 2x3 factorial experimental design was used to randomly assign 300 one-day-old male broilers to six experimental groups. The experimental groups included three different HFE additions (0, 0.2, and 0.4 mL/L) and two different ambient temperatures (24 and 35 °C). Each experimental group consisted of five replicates, with 10 chicks (initial body weight 38±4 g) per replicate. The study results indicated that heat stress (IIS) led to a decline in tibia dry weight, length, wet weight, volume, Seedor index, cortex thickness, shear force and shear stress, while concurrently resulting in an increase in dry matter percentage (P<0.05). Heat stress led to a decline in the levels of calcium (Ca), magnesium (Mg), copper (Cu), iron (Fe), zinc (Zn) and potassium (K) (P<0.05). The addition of HFE in the drinking water of broiler chickens exposed to HS did not significantly affect the morphological and biomechanical properties of the tibia. However, tibial Ca levels increased with the addition of 0.2 mL/L HFE, while Mg and Zn levels were elevated at both 0.2 and 0.4 mL/L HFE concentrations compared to the control group (P<0.05). In contrast, Fe and Mn levels decreased with 0.2 mL/L HFE supplementation, and K levels were reduced at both supplementation levels compared to the control (P<0.05). The findings suggest that the addition of 0.2 mL/L HFE to the drinking water of heat-stressed broiler chickens may be an effective and recommended strategy to enhance bone quality characteristics.
- MakaleAçık Erişim2025Effects of Varying Ratios of Hawthorn Fruit Extract on Nesfatin-1, GLP-1 and cTnI Response in Streptozotocin-induced Diabetic Rats
Özcan, G. Böyük; Kaya, H.
Background: The aim of this study was to investigate the ef fects of Hawthorn (Crataegus oxyacantha) Fruit Extract on the response of nesfatin-1, Glucagon-like peptide 1 (GLP-1) and cardiac troponin I (cTnI) in STZ-induced diabetic rats. Methods: This study utilized 64 adult male Wistar albino rats, aged 8-10 weeks and weighing an average of 195-215 g. Eight groups were randomly selected, each comprising eight rats designated as Control (C), H100, H200, H300; Diabetes Control (DC), DH100, DH200, DH300. Blood samples were collected from the tail vein (vena caudalis) of all individuals on days 0 and 21 of the research. The serum levels of Nesfatin-1, GLP-1 and cTnI were quantified and assessed using the ELISA technique. Result: In diabetic groups, the increase in serum mean nesfatin-1 and cTnI levels was most pronounced in DC groups, while the most significant decrease due to increased HFE supplementation was observed in DR200 groups (p<0.01); whereas in diabetic groups, the decrease in serum mean GLP-1 levels was observed in DC group, while the most significant increase due to increased HFE supplementation was detected in DG200 group. As a result, it was concluded that 200 mg/kg RPE administration to healthy and di abetic rats di d not cause any side eff ects. It was concluded that HFE, which has an anti-diabetic eff ect by regulating the inflammatory response that plays a role in the development of diabetes, decreasing nesfatin-1 levels and increasing GLP-1 levels, may be useful in supporting the impaired pancreatic beta cell function that occurs in diabetes.
- MakaleAçık Erişim2025Investigation of the relationship between apelin hormone response and some physiological parameters in enzootic bovine leukosis virus infected cattle
Sait, A.; Bayraktar, B.; Korkmaz, S.; Genç, M.; Bayraktar, S.; Kotan, G. C.; Aydemir, S.; Takma, C.; Bülbül, A. S.; Aksakal, V
Apelin is a hormone with lymphangiogenesis potential, associated with tumor growth and lymph node metastasis, and is reported to stimulate tumor vascularization. This study aimed to investigate the response of the apelin hormone in cattle with and without Enzootic Bovine Leukosis (EBL) infection, based on physiological parameters such as breed, age, and body condition score (BCS). A total of 120 Simmental and Montafon cattle of varying ages (<2, 2-8, and >8) and BCS categories (<2, 3-3.5, and >= 4) were included in the study. Serum apelin hormone levels were measured using the ELISA technique in blood samples collected from the neck vein ( Vena jugularis) of the animals. The analysis of mean serum apelin (ng/mL) values revealed that, among EBL-positive cattle, the highest value was 2.77 ng/mL in Simmental cattle aged 2-8 years with a BCS of 3-3.5, while a value of 2.69 ng/mL was observed in Montafon cattle aged >8 years with a BCS of 3-3.5. For EBL-negative cattle, the highest mean serum apelin value was 2.24 ng/mL, recorded in Simmental cattle aged 2-8 years with a BCS of 3-3.5, whereas it was 1.45 ng/mL in Montafon cattle aged >8 years with the same BCS. In conclusion, this study demonstrated for the first time the effect of apelin hormone levels in cattle with or without EBL, depending on physiological parameters such as age, breed, and BCS. It is suggested that the apelin hormone, which is involved in neoplastic lymphocyte cell infiltration in the lymphoreticular tissues of cattle, and plays a role in regulating tumor growth in EBL, a malignant tumor disease, may contribute to eradication programs. Moreover, the evaluated parameters may prove valuable for disease prevention and control strategies.
- MakaleAçık Erişim2024Investigation of Microbiological, Physiological and Histopathological Changes in Polymicrobial I nfection in Old Rats
Ulker, U.; Kizil, S.; Bayraktar, B.; Alçigir, M. E.; Kul, O.; Kaya, H.; Ürüsan, H.; Aydemir, S.; Kotan, G. C.; Önel, A. U.
Background: The aim of this study is to examine the microbiological, clinical, physiological and pathological findings of natural polymicrobial infection developing in a wistar rat colony under long-term observation. Methods: In this study, 70 male Wistar albino rats, 3 years old, raised by conventional methods and housed in a cage environment were used. Thirteen rats with clinical symptoms such as torticollis and rotation were sacrificed for microbiological and histopathological examination after 14 days. For microbiological examination, the rapid diagnostic kit BBL Crystal system was used to identify bacterial agents in tissue and stool samples and the traditional culture method was used for isolation. Result: As a result of microbiological analysis, the rarely isolated Staphylococcus capitis ( S. capitis ) was isolated. Different Staphylococcus spp. It has been determined that the species can cause suppurative meningoencephalitis as well as septicemia in the brains of experimental animals., it is thought that polymicrobial infection will be useful for the identification of bacterial agents and infection prevention and treatment strategies.
- MakaleAçık Erişim2023The Effect of Organic Hawthorn (Crataegus tanacetifolia) Fruit Vinegar Supplement on Growth Performance, Carcass Characteristics and Some Serum Parameters in Broiler Chickens Subjected to Cyclic Heat Stress
Kaya, H.
Background: This study, it was aimed to determine the effects of adding organic hawthorn (Crataegus tanacetifolia) fruit vinegar (HFV) in different doses to the drinking water of broiler chickens reared under cyclic heat stress (CHS) on performance, carcass characteristics and some serum parameters. Methods: In the study, 300 one-day-old broiler chickens (Ross 308), after a 1-week acclimation period, were tested in two different (24 and 35◦C) ambient temperatures and three different HFV levels (0, 2 and 4 ml/L) according to the 2×3 factorial experimental design. Chicks were randomly distributed to 6 experimental groups with 5 replications, with 10 animals in each replication. The addition of organic HFV to the drinking water of broiler chickens subjected to CHS didn’t affect growth performance, carcass characteristics and visceral weight (P>0.05). Addition of HFV increased serum FFA level, decreased serum MDA, HDL and TAG levels (p<0.05) and did not affect other serum parameters (P>0.05) in CHS-treated groups. Result: As a result, it was concluded that the addition of HFV to the drinking water of broiler chickens exposed to cyclic heat stress did not have any negative effect on growth performance, carcass characteristics and visceral weights, but it could be beneficial in preventing lipid peroxidation.
- MakaleAçık Erişim2021Tarragon (Artemisia dracunculus l.) could alleviate negative effects of stocking density in laying hens
Kaya, H.; Karaalp, M.; Kaynar, Ö.; Tekçe, E.; Aksakal, A.; Bayram, B.
The study was conducted to determine the effects of stocking density (SD, 5 or 7 layers/cage) and tarragon (Artemisia dracunculus L.) diet supplementation at four levels (0, 1.2, 6 and 12 g/kg feed) on performance, certain egg characteristics, serum, liver, egg yolk and small intestine bacteria parameters in laying hens. The experiment was carried out over a period of 8 weeks, with 192 Lohman Brown commercial hybrids at 50-w-age. The results showed that an increased SD reduced feed intake (FI; p<0.01) and egg production (p<0.05), but had no effect on the weight gain, feed conversion ratio, damaged egg ratio, egg weight and egg quality (p>0.05) parameters. The supplementation of tarragon to the diet reduced the FI and damaged egg ratio (p<0.01), and improved egg production and FCR (p<0.01). While an increased SD reduced serum total antioxidants (p<0.05), it elevated corticosterone (CORT) and total oxidant serum (TOS) (p<0.05). Tarragon was found to enhance total immunoglobulin (p<0.05), but to decreased the CORT and TOS of the serum (p<0.05). An increased SD raised the malondialdehyde (MDA) in the serum (p<0.001), liver (p<0.05) and yolk (p<0.001). Tarragon supplementation reduced MDA of the serum (p<0.05), liver (p<0.001) and yolk (p<0.001). E. coli and total Mesophilic Aerobic Bacteria counts in the small intestine were raised (p<0.001) with increased SD. Tarragon decreased (p<0.05) mesophilic aerobic bacteria. It was thus found that, tarragon supplementation can be considered generally effective in improving performance parameters, alleviating stress-induced negativities, reducing lipid peroxidation, regulating the immune system and controlling some intestinal microorganisms.
- MakaleAçık Erişim2020Influence of lactobacillus reuteri on internal organ weight, performance and meat quality of Japanese quail (Coturnixcoturnix japonica) under heat stress; [Einfluss von lactobacillus reuteri auf das gewicht der inneren organe, die leistung und die fleischqualität Japanischer Wachteln (Coturnix coturnix japonica) unter Hitzestress]
Tekce, E.; Bayraktar, B.; Aksakal, V.; Dertli, E.; Kamiloğlu, A.; Çinar Topçu, K.; Kaya, H.; Takma, C.; Yasulergezer, N.
In the present study, the effects of Lactobacillus reuteri E81 (LRE) supplemented at different doses (200, 400 and 600 mg/kg) into the diets on performance, meat quality and internal organ weights of Japanese quail (Coturnixcoturnix japonica) were investigated under heat stress (HS) conditions (37°C). For the experiments, 448 one-day old quails were used. Seven days of training (physical exercise) and a 35-day fattening period were applied. On day 7 of the trial, 8 groups [4 under control temperature of 25°C (CT): control (C), LRE-200, LRE-400 and LRE-600 and 4 under HS: control (HSC), SLRE-200, SLRE-400 and SLRE-600] were formed, each group consisting of four replicates with 14 quail each. At the end of this study, the CT group fed 400 mg/kg LRE showed the best performance results, whereas no effect was found for groups under HS in comparison to the control group (HSC). Samples taken on the 21st and 42nd day revealed that addition of probiotics in the CT and HS groups induced no effect on weight of the internal organs (p > 0.05). Analysis of meat quality on the 21st day showed that LRE caused an increase in pH in both the HS and CT groups. Further, 400-mg/kg LRE supplementation induced an increase in thiobarbituric acid reactive substances (TBARS) in the group under HS. In the CT groups on day 42 no effect of LRE was found on colour parameters or on the TBARS value, except for a decrease in the pH value in the LRE supplemented groups compared with the control. In HS groups a decrease in the L* value and an increase in the TBARS value was found compared to CT groups (p < 0.05), but there was no effect on other colour parameters or pH value. In conclusion, in the present study supplementation of different doses of LRE E81 to quail diets had no effect on performance, internal organ weight or meat quality under HS.
- MakaleAçık Erişim2020Effects of lactobacillus reuteri e81 added into rations of chukar partridges (Alectoris chukar) fed under heat stress conditions on fattening performance and meat quality
Tekce, Emre; Bayraktar, B.; Aksakal, V.; Dertli, E.; Kamiloğlu, A.; Çinar, K.; Takma, Ç.; Kaya, H.; Gül, M.
This study investigated the effects of the addition of Lactobacillus reuteri E81 (LRE) into rations of chukar partridges (Alectoris chukar) fed under heat stress (HS) conditions on fattening performance and meat quality. This study included 256 chukar partridges aged 1 day. The study comprised an adaptation period of 7 days and a fattening period of 35 days and included 8 different groups with 32 animals in each group. Each group was further divided into four subgroups with eight animals in each subgroup. At the end of the study, the best results in terms of fattening performance in the non-HS groups were obtained in the LRE 600 ppm group and in the HS groups, SLRE 200 ppm had the best effect on average live weight and average live weight increase, whereas SLRE 400 ppm had the best effect on FCR (p<0.05). The analysis of the samples collected from chukar partridges on day 21 showed that, there was no effect on the colour parameters and Thiobarbituric acid reactive substances (TBARS) level in the LRE in the HS and non-HS groups, whereas the meat pH level decreased in the SLRE 400 ppm group (p<0.05). The analysis of the samples collected on day 42 showed that there was no effect on colour parameters in the HS and non-HS groups. TBARS level decreased at the dose of LRE 200 ppm in the non-HS group, and the meat pH level decreased in both HS and non-HS groups (p<0.05).