Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleYalnız künye2026Nicotinamide complexes of metal(II) furan-2-carboxylates: synthesis, determination of crystal structures, Hirshfeld surface analysis, and in vitro and in silico evaluation of inhibitory properties on CA I, CA II, AChE, BChE, and GR enzymes
Nar, Merve; Senturk, Murat; Kaya, Afşin Ahmet; Öztürkkan, Füreya Elif; Kaya, Elif Çelenk; Şahin, Ertan
In this study, nicotinamide complexes of Cu2⁺, Co2⁺, and Zn2⁺ furan-2-carboxylates were synthesized, and the crystal structures of the complexes were characterized by single crystal X-ray diffraction. The chemical composition and functional groups of the complexes were confirmed using elemental analysis, Fourier transform infrared spectroscopy (FT-IR), ultraviolet–visible region (UV–Vis) spectroscopy, and mass spectrometry (MS). Hirshfeld surface analysis detailed the intermolecular interactions present in the crystal structures of the complexes. The complexes feature a central six-coordinate ion (Cu2⁺, Co2⁺, or Zn2⁺) located on an inversion center, which is bonded to two N atoms from nicotinamide and four O atoms from water molecules. There is a furan 2-carboxylate anion that is not coordinated with metal atoms but links to complex structures via hydrogen bonds. Within the scope of biochemical studies, the inhibitory effects of the synthesized complexes on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase I and II (hCA I, hCA II), and glutathione reductase (GR) enzymes were investigated by spectrophotometric methods. It was determined that the complexes, especially Complex 2, exhibited strong enzyme inhibition properties. Molecular docking analyses revealed the binding tendencies and binding energies of the complexes to the active sites of the enzymes. Complex 2 has a high binding affinity with AChE, BChE, hCA I, hCA II, and GR enzymes, and these bindings were supported by hydrogen bonds and π-π interactions. ADMET predictions showed that the complexes have toxicologically safe profiles despite their pharmacokinetic limitations, such as low gastrointestinal absorption and inability to cross the blood–brain barrier. It was determined that the risks of hepatotoxicity, carcinogenicity, immunotoxicity, and mutagenicity were low. As a result, these metal complexes are evaluated as potential therapeutic agents in the treatment of diseases such as Alzheimer’s disease, glaucoma, epilepsy, malaria, and cancer. The data obtained in this study emphasize the biological activities and pharmacological potential of the complexes, and it is recommended that they be supported by future in vivo studies.
- MakaleAçık Erişim2025Kişisel Koruyucu Donanımların Kullanımında Çalışan Yaklaşımı: Malatya İlı̇ Cam Sanayı̇ Örneği
Kaya, Elif Çelenk; Ersoy, Sibel; Ertürk, Gülcan Aydemir
İş yerlerinde yaşanılan kaza ve meslek hastalıklarının önlenmesi, sağlıklı ve güvenli bir ortam oluşturulması için yapılacak çalışmalarda kişisel koruyucu donanım (KKD) kullanımı önemlidir. Araştırmamızda zorunlu olduğu halde iş güvenliği uygulamalarının gereklerine yeteri kadar uyulmaması sonucu ortaya çıkan iş kazası ve meslek hastalıklarını engellemekte önemli bir etken olan KKD’lerin kullanılmasında çalışan yaklaşımı değerlendirilmiştir. Bu çalışmada Malatya ilinde bulunan bir cam fabrikasında 123 çalışana KKD’lerin kullanımına yönelik anket uygulanmıştır. Elde edilen veriler SPSS 22, programı kullanılarak analiz edilmiştir. Bu çalışma ile, cam sektöründe yer alan bir iş yerinde çalışanların kişisel koruyucu donanımlar hakkındaki düşüncelerini ve kullanıma yönelik davranışlarını tespit etmek amaçlanmıştır. Araştırma sonuçlarına göre, çalışanlara kişisel koruyucu donanımlar ile ilgili yöneltilen sorularda çalışanların büyük bir kısmının (%82) KKD kullandığını, %99’unun KKD kullanımının önemli olduğuna inandığını, KKD kullanımının onları iş kazaları (%98) ve meslek hastalıklarından (%87) koruduğunu düşündükleri görülmektedir. Çalışanların büyük çoğunluğunun KKD kullanımını benimsemesi ve bunu iş kazaları ile meslek hastalıklarından korunmada etkili görmesi, iş güvenliği kültürünün gelişiminde eğitim ve farkındalık çalışmalarının belirleyici olduğunu ortaya koymuştur.
- MakaleYalnız künye2022Fine-Kinney Metodu İle Risk Analizi: Trabzon Liman Örneği
Kaya, Elif Çelenk; Bayram, Hakan
Dünyada ve ülkemizde karayolu, havayolu, demiryolu, deniz yolu gibi çeşitli taşıma yöntemleri kullanılmaktadır. Diğer taşıma yöntemlerine göre uluslararası ticaretin %80-90'ı deniz taşımacılığı ile yapılmaktadır. Denizyolu taşımacılığı ile ağır yükler, tehlikeli kimyasallar, yüksek hacimli yükler daha ucuz ve güvenli bir şekilde taşınmaktadır. Dünyada deniz taşımacılığının fazla kullanılması limanların önemini artırmaktadır. Ülkemizde limanlarımız tehlikeli işyerleri olarak sınıflandırılmaktadır. Yüklenen ve taşınan tehlikeli kimyasallar, farklı makine ve araçların bulunması, liman operasyonlarından kaynaklanan çeşitli riskler içermektedir. Tehlike ve riskleri ortadan kaldırılması için sağlık ve güvenlik önlemleri alınmalıdır. Limanlarda teknik personel eksikliği, limanlarda çeşitli risklerin ve tehlikelerin bulunması, makinelerin, araçların, özel ekipmanların bulunması ve çeşitlilik göstermesi, yabancı personellerin bulunması, liman sahasının genişliği gibi faktörler limanlarda önleyici ve düzenleyici çalışmaların yapılmasını zorlaştırmaktadır Bu çalışmada Trabzon Limanı kapsamında tehlike kaynakları ve riskler belirlenmiş ve risk değerlendirme yöntemi olan Fine-Kinney yöntemi kullanılarak risk analizi çalışması hazırlanmıştır. Trabzon limanını kapsayan risk analizinde 13 tane “Tolerans Gösterilemez Risk”, 19 tane “Esaslı Risk”, 40 tane “Önemli Risk” olmak üzere toplam 72 tane risk tespit edilmiştir.
- MakaleAçık Erişim2022İş Sağlığı ve Güvenliğinde Kimyasal Risk Faktörleri: Çalışanların Karbonmonoksit (CO) Maruziyeti
İri, Necla İrem Ölmezoğlu; Kaya, Elif Çelenk; Ketenci, Huseyin Cetin; Ersoy, Sibel; Karadeniz, Hülya
Çalışma ortamlarında çalışanların sağlık ve güvenliğini olumsuz etkileyen tehlike kaynaklarının başında kimyasal tehlikeler gelmektedir. Basit boğucu, irritan ve kimyasal boğucu olarak sınıflandırılan gaz formundaki kimyasallar ise çalışma ortamları için ciddi riskler taşımaktadır. Bu çalışmada egzoz gazlarına maruz kalan Gümüşhane ilindeki benzin dağıtıcıları, taksi-otobüs şoförleri ve otomotiv sanayi çalışanlarının karboksihemoglobin (COHb) seviyelerinin belirlenmesi, sağlıklı ve güvenli ortamda çalışmaları için iş sağlığı ve güvenliği (İSG) tedbirlerinin önerilmesi amaçlanmıştır. Çalışmada meslekleri gereği CO’e maruz kalan çalışanlardan ve CO’e maruz kalmayan kontrol grubundan kan örnekleri alınmış ve COHb saturasyon yüzdeleri CO-Oximetri cihazı ile tayin edilmiştir. COHb seviyelerinin sigara içme alışkanlıkları, mesleki deneyimleri, İSG eğitimi alıp almama durumları arasındaki ilişkilerin belirlenmesi için 11 soruluk yarı yapılandırılmış anket uygulanmış, sonuçlar SPSS programı ile değerlendirilmiştir. Çalışmanın sonucunda egzoz gazına maruz kalanların COHb seviyeleri ile kontrol grubu arasında anlamlı farklılıklar ortaya konulmuştur. %COHb düzeyleri ile çalışanların mesleki deneyimleri, İSG eğitimi alıp almama durumları gibi değişkenler incelendiğinde bu değişkenlerin sonucu etkilemediği görülmektedir.
- MakaleYalnız künye2019Investigation of Inhibition Effect of Nitro Group Containing Substances on Glutathione Reductase Enzyme
Şentürk, Murat; Kaya, Elif Çelenk; Kaya, Afşin Ahmet
Glutathione reductase (Glutathione: NADP+ oxidoreductase, EC 1.8.1.7; GR) catalyzes electron transfer between reduced (GSH) or high molecular weight (GSSG) disulfide substrates and reduced pyridine nucleotides (NADPH). Discovery of glutathione reductase (GR) inhibitors has become very popular recently due to antimalarial and anticancer activities. Enzymatic activity was measured by Beutler’s method with a Spectrophotometer, at 25°C. The assay system contained 100 mM Tris-HCl buffer pH 8.0, including 0.5 mM EDTA, 3.3 mM GSSG and 0.1 mM NADPH. Inhibition effects of Nitrobenzene (1), 3,5- Dinitrosalicylic acid (2), (2,4-Dinitrophenyl)((4-(prop1-en-2-yl)cyclohex-1-enyl)-methyl)sulfane (3), ((7,7- dimethylbicyclo[2.2.1]heptan-1-yl)methyl)-(2,4- dinitrophenyl)sulfane (4), and ((2-Chloro-7,7- dimethylbicyclo[2.2.1]heptan-1-yl)methyl)-(2,4- dinitrophenyl)sulfane (5) compounds on GR have been investigated in vitro. IC50 values were determined by drawing % activity- [I] graphs for compounds showing inhibition effects. IC50 values of GR for these substances were observed to be at micromolar level.
- MakaleYalnız künye2019A Risk Analysis Implementation of a State University Food Engineering Department’s Laboratories
Kaya, Elif Çelenk; Ersoy, Sibel
According to the work health and safety law no:6331; employers of the corporations which is subjected to that law have to make the risk assessment or have it made. It is known that the best effective method of preventing the work accidents and occupational diseases is the risk assessment. By the risk assessment, potantial dangers and the risks sourced by them are revealed and thus, with effective precautions, preventations of the work accidents and occupational diseases are trying to be done. The laboratories as their nature, hosts serious dangers and the risks sourced by them. To eliminate or minimise these risks the implementations of collective protection precautions, taking series of precautions begining from the design and installation process, setting up the substructure of work safety, informing the employees about the dangerous situations and the education of laboratory safety has a great importance. Revealing the risk factors in the laboratories with the actual risk assessment methods and taking effective precautions in a short time is very important for work safety. There are limited number of studies in the literature that are subjected to the risk assessments of laboratories. In this study, using the control lists of the relevant ministry, danger and risks of six number of application and research laboratories of a state university food engineering department have been identifed and by the L type matrix method, the risk analysis study has been made. At the laboratories which this study has been made a total of 52 number of risks consist of 6 number of unacceptable risks, 24 number of high level risks, 19 number of middle level risks and 3 number of low level (acceptable) risk have been determined. A risk score has been generated for each risk and the average risk score of 15 high level risk has seen for all laboratories. By taking into consideration of the risk scores, providing the work health and security, a legal control and precaution operations which are sustainable and effective have been suggested.
- MakaleYalnız künye2019Enhancing of the nonlinear absorption and optical limiting performances of the phthalocyanine thin films by adding of the single walled carbon nanotubes in poly(methyl methacrylate) host
Yuksek, Mustafa; Kaya, Elif Çelenk; Karabulutlu, Nur; Kaya, Ahmet Afşin; Karabulut, Mevlut; Elmali, Ayhan
Unlike the earlier nonlinear optical studies of single walled carbon nanotubes (SWCNTs) which were generally carried out as solvent, in this study, we established to deposit the unsoluble SWCNTs as homogeneous thin films by blending them with phthalocyanines in PMMA host. The structural and morphological features of the thin films were studied by SEM and TEM imaging techniques while the linear, nonlinear-absorptions and carrier dynamic properties of the thin films were investigated with the UV–Vis spectrophotometer, open aperture Z-scan experiments and pump-probe technique, respectively. In addition, the optical limiting performances of the samples were calculated from nonlinear absorption spectra. It was observed that the linear- and nonlinear-absorptions and optical limiting performance of the thin films increased with the mixing of the SWCNT sample with the Pcs complexes. We have clearly explained the mechanisms contributing to the nonlinear optical absorption and optical limiting performances.
- MakaleYalnız künye2018İş Güvenliği Uzmanlarının Yaşadığı Sorunlar
İri, Necla İrem Ölmezoğlu; Kaya, Elif Çelenk; Takaoğlu, Zeynep Başkan
İş sağlığı ve güvenliği çalışmaları öncesi var olmasına rağmen son zamanlarda üzerinde daha çok konuşulan bir konu halini almıştır. Kuşkusuz bu durumun temelinde sayıları her geçen gün artan iş kazaları ve meslek hastalıkları gelmektedir. İş kazası ve meslek hastalıklarını önlemede üstlendiği rol düşünüldüğünde iş güvenliği uzmanları konunun başlıca muhatabı olarak karşımıza çıkmaktadır. 2012 yılında yürürlüğe giren İş Sağlığı ve Güvenliği Kanunu ile birlikte işyerlerinde çalışan sayısı ve tehlike sınıfı dikkate alınarak iş güvenliği uzmanından hizmet alınması yükümlülüğü getirilmiştir. Ayrıca uzmanların bu faaliyetleri yerine getirmede yetki, sorumluluk ve yükümlülükleri 28512, 28545 ve 28792 sayılı yönetmeliklerde belirtilmektedir. Ancak, farklı sektörlerde görev yapan bu uzmanlar bazı sorunlarla karşılaşmaktadır. Bu sorunların tespit edilmesi, detaylı olarak ele alınarak çözüm önerilerinin sunulması bu çalışmanın ana amacını temsil etmektedir. Bu konuyu ele alan çalışmalar bulunsa da çalışmamız farklı bir yöntem ile ele alınması bakımından diğerlerinden ayrılmaktadır. Çalışmamız kapsamında öncelikle iş güvenliği uzmanlığı mesleği ve bu mesleğin yetki ve sorumlulukları hakkında genel bilgilere yer verilecek olup ardından yapılan saha çalışmalarının bulguları tartışılarak çözüm önerilerinde bulunulacaktır.
- MakaleYalnız künye2018How Much Important is the Risk Assessment? “Employer’s Point of View”
İri, Necla İrem Ölmezoğlu; Kaya, Elif Çelenk; Takaoğlu, Zeynep Başkan
According to the Law on Occupational Health and Safety No. 6331 dated 30/06/2012, one of the important obligations of an employer is to make / have a 'Risk Assessment'. Besides the risk assessment, it is the employer's obligation to provide the occupational health and safety precautions that should be taken according to the risk assessment result, as well as the protective equipment to be used. Given the responsibility in this regard, employers should be familiar with the general information on risk assessment, such as the risk assessment team, periodic renewal period of the risk assessment according to hazard class, deadline, criminal sanctions if the risk assessment does not performed; they should examine the risk assessment prepared by the experts in detail; and they should have knowledge about the precautions that should be taken. If the employers do not place the necessary importance on the risk assessments prepared in order to eliminate or minimize the risks by taking the required precautions, the analysis will be on paper and not reach its real target. In this study, it was aimed to determine whether or not a risk assessments for less dangerous, dangerous and very dangerous workplaces in Gümüşhane was made, risk assessment knowledge of the employers and to what extent they examined the risk analyses prepared for their workplaces.
- MakaleAçık Erişim2017Synthesis, spectroscopic characterization, X-ray structure and DFT calculations of Ni(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) dihydrate
Kaya, Elif Çelenk; Kaya, Afşin Ahmet; Demircioǧlu, Zeynep; Büyükgüngör, Orhan
A single crystal of Ni(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) dihydrate, formulated as C30H34N4NiO12 (I), was characterized in the solid state by infra-red (IR), ultra-violet (UV) and single crystal X-ray diffraction analysis at 296 K as mononuclear with a distorted octahedral stereochemistry. The complex consists of a six-coordinate Nickel atom in a distorted octahedral environment constructed from two N atoms and four O atoms and crystallizes in the monoclinic space group C 2/c with a=27.7680(16) Å, b=8.5748(3) Å, c=17.8018(9) Å, α=90°, β=108.154(4)°, γ=90°, Z=4. The molecular structure and geometry was also optimized using the B3LYP density functional theory method employing the 6-31G(d) basis set. The molecular electrostatic potential (MEP), frontier molecular orbitals (FMO) analysis, nonlinear optical properties (NLO) and natural bond analysis (NBO), Mulliken population analyis, natural population analysis (NPA) and Fukui function analysis were also described.
- MakaleAçık Erişim2016Kinetic and in silico studies of hydroxy-based inhibitors of carbonic anhydrase isoforms I and II
Ekhteiari Salmas, Ramin; Mestanoglu, Mert; Durdagi, Serdar; Sentürk, Murat; Kaya, A. Afşin; Kaya, Elif Çelenk
A series of hydroxy and phenolic compounds have been assayed for the inhibition of two physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isozymes, the cytosolic human isozymes I and II. The investigated molecules showed inhibition constants in the range of 1.07-4003 and 0.09-31.5 μM at the hCA I and hCA II enzymes, respectively. In order to investigate the binding mechanisms of these inhibitors, in silico studies were also applied. Molecular docking scores of the studied compounds are compared using three different scoring algorithms, namely Glide/SP, Glide/XP and Glide/IFD. In addition, different ADME (absorption, distribution, metabolism and excretion) analysis was performed. All the examined compounds were found within the acceptable range of pharmacokinetic profiles.
- MakaleYalnız künye2015Çağrı merkezinde çalışan müşteri temsilcilerinin çalışma ortamlarının ergonomik analizi
İri, Necla İrem Ölmezoğlu; Özaydın, Mehmet Merve; Kaya, Elif Çelenk
"İşbilimi" meaning of ergonomics-related studies are gaining more importance with each passing day. However, the call center industry in the world, in Turkey, 11.5 million more than 30,000 people running. With each passing day, this number is increased even further if you think about the employees ' ergonomic design of the business environment is very important in terms of business efficiency. We're in the same position for a long time employees, the work carried out by the appropriate table, Chair, or in the case of strongly support equipment, back pain, neck or shoulder injury, such as pain in the legs or feet, muscle and skeletal system diseases, circulatory system disorders can also be confronted with serious health problems, In addition, ambient lighting, noise, and some physical risk factors such as thermal comfort of employees on productivity is extremely important. In this context, the aim of this study was to study the suitability of the conditions of ergonomic aspects in mind when in a call center is intended to investigate the problems of employees ' ergonomic. In the study, call center employees made the implementation of the survey results in the SPSS package program by using statistical analysis methods with interpreted and evaluated
- MakaleYalnız künye2015Synthesis, X-Ray Structural, Characterization, NLO, MEP, NBO, and HOMO-LUMO Analysis Using DFT Study of Co(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) Dihydrate
Kaya, Elif Çelenk; Demircioʇlu, Zeynep; Kaya, Afşin Ahmet; Büyükgüngör, Orhan
A suitable single crystal of Co(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) dihydrate, formulated as C30H38N4O14Co,(I). According to experimental data, the complex can be characterized in the solid state as mononuclear, with a distorted octahedral stereochemistry. The distorted octahedral stereochemistry adopted by the complex was further confirmed by the x-ray structure analysis of current study, which consists of a six-coordinate Co atom in a distorted octahedral environment constructed from two N atoms and four O atoms. The title compound which has been characterized by IR, UV, and single crystal X-ray diffraction analysis at 296 K crystallizes in the monoclinic space group C 2/c with a = 27.9402(15) Å, b = 8.6005(3)Å, c = 14.7921(9)Å, α = 90°, β = 108.849(4)°, and γ = 90°, Z = 4. The molecular structure and geometry have also been optimized using B3LYP density functional theory method employing the 6-31G (d) basis set. The molecular electrostatic potential (MEP), frontier molecular orbitals (FMO) analysis, nonlinear optical properties (NLO), and natural bond analysis (NBO) for the title molecule are also described from the computational process.
- MakaleAçık Erişim2014Synthesis and spectral and thermal characterization of new metal-free and metallophthalocyanines: Investigation of their photophysical, photochemical, and thin film properties
Kaya, Elif Çelenk; Durmuş, Mahmut; Yanmaz, Ekrem; KantekiN, Halit
Novel tetrasubstituted metal-free (2), zinc (II) (3), cobalt (II) (4), and copper (II) (5) phthalocyanines bearing 2-phenylethanolate groups on the peripheral positions were synthesized by the cyclotetramerization reaction of the phthalonitrile derivative 1. The new compounds were characterized by a combination of IR, 1H NMR, 13 C NMR, UV-Vis, elemental analysis, and MS spectra data. The thermal stabilities of the phthalocyanine compounds were determined by thermogravimetric analysis. For metal-free (2) and zinc (3) phthalocyanines, photochemical (photodegradation and singlet oxygen quantum yields) and photophysical (fluorescence quantum yields and fluorescence lifetimes) properties were analyzed in dimethylsulfoxide (DMSO). The cobalt (4) and copper (5) phthalocyanines were not evaluated for this purpose because of their paramagnetic behavior. The metal-free (2) and zinc (3) phthalocyanines' fluorescence quenching behaviors were also investigated. The new phthalocyanine compounds' fluorescence emissions were effectively quenched by 1,4-benzoquinone in DMSO. The thin films of the cobalt phthalocyanine compound (4) were grown by electron beam evaporation technique. Crystalline CoPc (4) thin films were investigated by X-ray diffraction spectroscopy. Surface morphology of the CoPc (4) thin films was characterized by SEM.
- MakaleYayıncıda açık erişim2014Synthesis, X-ray structural characterization, NLO, MEP, NBO and HOMO-LUMO analysis using DFT study of Zn(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) dihydrate
Kaya, Afşin Ahmet; Demircioǧlu, Zeynep; Kaya, Elif Çelenk; Büyükgüngör, Orhan
A single crystal of Zn(II)bis(3,4 dimethoxybenzoate)bis(nicotinamide) dihydrate, formulated as C30H38N4O 14Zn, (I) has been obtained. According to experimental data, the complex can be characterized in the solid state as mononuclear, with a distorted octahedral stereochemistry. The distorted octahedral stereochemistry adopted by the complex was further confirmed by X-ray structure analysis of the current study, which consists of a six-coordinate Zn atom in a distorted octahedral environment constructed from two N atoms and four O atoms. The title compound crystallizes in the monoclinic space group C 2/c with a = 27.9248(18) Å, b = 8.5941(4) Å, c = 14.8344(11) Å, α = 90°, β = 108.651(5), γ = 90°, Z = 4. The molecular structure and geometry were also optimized using the B3LYP density functional theory method employing the 6-31G (d) basis set. Molecular electrostatic potential, frontier molecular orbital analysis, nonlinear optical properties and natural bond analysis for the title molecule are also described from the computational process.
- MakaleYalnız künye2012Synthesis and characterisation of new metallophthalocyanines containing four 12-membered diazadithia-macrocyclic moieties
Kaya, Elif Çelenk; Kantekin, Halit; Kaya, Afşin Ahmet; Dakoǧlu, Asuman; Öksüz, Sümeyra; Şişik, Hanife
Tetrasubstituted zinc, cobalt, nickel, copper and lead phthalocyanines bearing four 12-membered diazadithia macrocyclic moieties on peripheral positions have been synthesised by cyclotetramerisation reaction of 1,10-ditosyl-1,2,3,5,6,8,9,10-octahydrobenzo[h][1,4,7,10] dithiadiazacyclododecine-12,13-dicarbonitrile and corresponding anhydrous metal salts under microwave irradiation. The thermal stabilities of the phthalocyanine compounds have determined by thermogravimetric analysis.
- MakaleAçık Erişim2012Synthesis and antimicrobial activity of new phthalocyanine complexes and electrochemical and spectroelectrochemical behaviour of cobaltphthalocyanine
Kaya, Elif Çelenk; Karadeniz, Hülya; Koca, Atif; Kahriman, Nuran; Sökmen, Atalay
A novel phthalocyanine bearing oxygen donor atoms on the peripheral positions has been synthesised by cyclotetramerisation of (E)-4-(4- cinnamoylphenoxy) phthalonitrile and its nickel, zinc, cobalt, copper and lead derivatives prepared. The thermal stabilities of the phthalocyanine compounds have been determined and their possible biological activities (antibacterial, anticandidal and antifungal) studied. The effects of substituent on the electrochemical and in situ spectroelectrochemical behaviour of cobaltphthalocyanine have been investigated and an in situ electrocolorimetric method was applied to investigate the colour of the electrogenerated anionic and cationic forms of the complex.
- MakaleAçık Erişim2012Synthesis and characterization of new metallophthalocyanines bearing macrocyclic N 3O 2 groups on peripheral positions
Kaya, Elif Çelenk
The synthesis and characterization of new zinc(II) 3 , nickel(II) 4 and cobalt(II) 5 phthalocyanines complexes carrying macrocyclic N 3 O 2 groups on peripheral positions are described. The compounds were characterized by elemental analysis, IR, 1 H and 13 C NMR, UV-Vis and MS spectral data.