Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2018Synthesis of fluorine-containing phthalocyanines and investigation of the photophysical and photochemical properties of the metal-free and zinc phthalocyanines
Çelenk Kaya, Elif; Ersoy, Sibel; Durmuş, Mahmut; Kantekin, Halit
4-(3-(Trifluoromethyl)benzylthio)phthalonitrile (1) was synthesized. Metal-free phthalocyanine 2, zinc(II) phthalocyanine 3 and cobalt(II) phthalocyanine 4 were synthesized starting with dinitrile compound 1. Photodynamic therapy properties of 2 and 3 were studied.
- MakaleYalnız künye2012Synthesis and characterisation of new metallophthalocyanines containing four 12-membered diazadithia-macrocyclic moieties
Kaya, Elif Çelenk; Kantekin, Halit; Kaya, Afşin Ahmet; Dakoǧlu, Asuman; Öksüz, Sümeyra; Şişik, Hanife
Tetrasubstituted zinc, cobalt, nickel, copper and lead phthalocyanines bearing four 12-membered diazadithia macrocyclic moieties on peripheral positions have been synthesised by cyclotetramerisation reaction of 1,10-ditosyl-1,2,3,5,6,8,9,10-octahydrobenzo[h][1,4,7,10] dithiadiazacyclododecine-12,13-dicarbonitrile and corresponding anhydrous metal salts under microwave irradiation. The thermal stabilities of the phthalocyanine compounds have determined by thermogravimetric analysis.
- MakaleAçık Erişim2012Optimization of a new cloud point extraction procedure for the selective determination of trace amounts of total iron in some environmental samples
Duran, Celal; Özdeş, Duygu; Çelenk Kaya, Elif; Kantekin, Halit; Bulut, Volkan Numan; Tüfekçi, Mehmet
A new, simple, and rapid cloud point extraction (CPE) procedure system, combined with flame atomic absorption spectrometry (FAAS), was developed for selective separation, preconcentration, and determination of trace amounts of total iron in some environmental samples. The complexing agent, N,N-(2,2 - (ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(2-chloroacetamide) (EDBOCA), is selective at pH 5.0 for only Fe(II) and Fe(III) ions in the presence of Cu(II), Pb(II), Cd(II), Mn(II), Co(II), Cr(III), Cr(VI), Ni(II), Zn(II), Al(III), Mo(VI), Pd(II), Pt(IV), Au(III), and V(V) ions. The procedure is based on the complexation of Fe(III) ions with EDBOCA reagent in the presence of Triton X-114 (TX-114) as a non-ionic surfactant. The optimum conditions for the CPE of Fe(III) ions were investigated with respect to several experimental parameters such as pH of the solution, TX-114 and EDBOCA concentrations, incubation time and temperature, and centrifugation rate and time. The detection limit for Fe(III) ions based on the 3 times the standard deviation of the blanks (N:10) was found to be 1.22 μg L ?1 , while the relative standard deviation (RSD) was 4.2%. Environment Canada TM-25.3 and CRM-SA-C Sandy Soil C, as certified reference materials, were used, and spike tests were applied to validate the method. The method was applied to some real environmental samples to evaluate their total iron levels.
- MakaleYalnız künye2011Microwave-assisted synthesis and characterization of novel symmetrical substituted 19-membered tetrathiadiaza metal-free and metallophthalocyanines and investigation of their biological activities
Nas, Asiye; Kaya, Elif Celenk; Kantekin, Halit; Sökmen, Atalay; Çakir, Volkan
This work reports on a new symmetrically substituted metal-free phthalocyanine and its transition metal complexes which were prepared by a condensation of N,N'-[propan-1,3-diilbis(tiyoetan-2,1-diil)]bis(4-methylbenzenesulfonamid) (1) and 1,2-bis(2-iodomercaptoethyl)-4,5-dicyanobenzene (2) with NiCl(2), ZnCl(2), CoCl(2), CuCl(2), and PbO salts in 2-(dimethylamino) ethanol, respectively. The phthalocyanines bearing thia and aza donor atoms at the peripheral position were characterized by IR, UV-Vis, (1)H NMR, (13)C NMR, Mass spectra, and elemental analysis data. The thermal behaviors of 4-9 were investigated by TG/DTA. Novel phthalocyanines were also investigated for enlightening their possible biological activities by employing antimicrobial (antibacterial and antifungal), antineoplastic and antioxidative assays. Of all tested, four samples exhibited antimicrobial activity against test microorganisms, among which, Branhamella catarrhalis was the most sensitive one with a MIC value around 0.312 mg/mL followed by a yeast, Candida albicans (MIC. 0.625 mg/mL). Due to their colored nature, the samples were found not to be applicable for antioxidative and antineoplastic assays. (C) 2011 Elsevier B. V. All rights reserved.
- MakaleAçık Erişim20114-[2-(Cyclohexa-1,4-dien-1-yl)ethoxy]-benzene-1,2-dicarbonitrile
Keleşoǧlu, Zeynep; Çelenk Kaya, Elif; Kaya, Afşin Ahmet; Kantekin, Halit; Büyükgüngör, Orhan
In the title compound, C16H14N2O, the dihedral angle between the aromatic rings is 70.23 (6)°. The linking chain has a zigzag conformation. In the crystal, molecules are linked by weak inter-molecular C - H⋯N hydrogen bonds, forming a zigzag chain along the c axis.
- MakaleAçık Erişim201017,18-Dibromo-8-methyl-4,12-ditosyl-3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-benzo[b][1,4,7,11,15]dioxatriazacycloheptadecine
Kelesoglu, Zeynep; Kaya, Elif Celenk; Kantekin, Halit; Bueyuekguengoer, Orhan
In the title compound, C31H39Br2N3O6S2, a 17-membered aza-macrocyclic ligand containing two ether O and three aza N atoms, the three pendant aromatic rings form an 'E' shape. The dihedral angles between the central benzene ring and the side ones are 17.8 (3) and 7.4 (3)degrees , and the dihedral angle between the tosyl rings is 10.6 (3)degrees . The methyl group is disordered over two orientations, with occupancies of 0.52 (15) and 0.48 (15).
- MakaleYalnız künye2010The synthesis and characterization of metal-free and metallophthalocyanine polymers by microwave irradiation containing diazadithia macrocyclic moieties
Kaya, Elif Celenk; Karadeniz, Huelya; Kantekin, Halit
A tetranitrile monomer was synthesized by nucleophilic aromatic substitution of N,N'-(2,2'-(propane-1,3-diylbis(sulfanediyl))bis(ethane-2,1-diyl))bis(4-methylbenzenesulfonamide) onto 4-nitrophthalonitrile. A metal-free phthalocyanine polymer was prepared by the reaction of the tetranitrile monomer under N-2 in the presence of 2-(dimethylamino)ethanol at 145 degrees C for 24 h. Zinc(II), copper(II), cobalt(II), nickel(II), lead (II), phthalocyanine polymers were prepared by reaction of the tetranitrile with the chlorides of zinc (II), copper (II), cobalt (II), nickel (II), lead (II), employing microwave irradiation in the presence 2-(dimethylamino)ethanol at 175 degrees C, 350 W for 10 min. The thermal stabilities of the phthalocyanine compounds were determined by thermogravimetric analysis. The new compounds were characterized by a combination of IR, H-1 NMR, C-13 NMR, UV-vis, elemental analysis and MS spectral data. (C) 2009 Elsevier Ltd. All rights reserved.