Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2018The effects of 4-vinylcyclohexene diepoxide on the testes of dogs; [Učinci 4-vinilcikloheksen diepoksida na testise pasa.]
Paksoy, Zahid; Kandemi̇r, Fatih M.; Gokhan, Nezihe; Ozkaraca, Mustafa
This study was aimed at investigating the effects of 4-vinylcyclohexene diepoxide (VCD) on testicular tissue in dogs. For this purpose, 30 mongrel male dogs were used and allocated to 5 groups randomly. The first group (n = 6), used as the control, was administered sesame oil by the intraperitoneal route (i/p). The VCD was administered i/p at doses of 80, 160, 240, 320 mg/kg to the second, third, fourth and the fifth groups (n = 6), respectively, once a day for 8 days. The dogs were surgically castrated on the day after the last VCD injection. The testes were removed immediately and fixed in 10% bouine solution. The testes were subjected to routine tissue processing and examined to determine the testicular damage in each testis. When compared to the control group, it was seen that the seminiferous tubule damage increased significantly in the treatment groups. Malondialdehyde levels reached the highest level in the fifth group, while superoxide dismutase, catalase, glutathione peroxidase activity and glutathione levels were higher in the control group (P<0.0001). Nosignificant difference was detected when all the groups were compared with respect to AST, ALT and GGT activities before and after the treatment (P>0.05). Our results showed that VCD may contribute to the sterilization of male dogs.
- MakaleAçık Erişim2010Meibomian carcinoma of the eyelid in a Simmental cow
Gokhan, Nezihe; Sozmen, Mahmut; Ozba, Burhan; Gungor, Emine
Objective: To describe the clinical and pathomorphological features of meibomian carcinoma (MC) diagnosed in a Simmental cow. Material and methods: A 7-year-old Simmental cow was admitted to the Veterinary Surgery Clinics of Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey. The signalment and anatomical distribution were summarized and focused on pathomorphological description. Results: Macroscopically, a papillary mass, 5 × 3.5 × 7 cm in size, arising from the left lower eyelid with local spread to the upper eyelid and covering the entire globe was observed. The mass was ulcerated and hemorrhagic and applied pressure to the globe. Following sedation and local anesthesia, the mass and globe were excised. Histopathological examination revealed an MC. Conclusions: The diagnosis of MC is infrequent in veterinary literature. Complete surgical excision could be curative and histopathology is crucial for the diagnosis of MC occurring in animals.