Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2025Investigation of the relationship between apelin hormone response and some physiological parameters in enzootic bovine leukosis virus infected cattle
Sait, A.; Bayraktar, B.; Korkmaz, S.; Genç, M.; Bayraktar, S.; Kotan, G. C.; Aydemir, S.; Takma, C.; Bülbül, A. S.; Aksakal, V
Apelin is a hormone with lymphangiogenesis potential, associated with tumor growth and lymph node metastasis, and is reported to stimulate tumor vascularization. This study aimed to investigate the response of the apelin hormone in cattle with and without Enzootic Bovine Leukosis (EBL) infection, based on physiological parameters such as breed, age, and body condition score (BCS). A total of 120 Simmental and Montafon cattle of varying ages (<2, 2-8, and >8) and BCS categories (<2, 3-3.5, and >= 4) were included in the study. Serum apelin hormone levels were measured using the ELISA technique in blood samples collected from the neck vein ( Vena jugularis) of the animals. The analysis of mean serum apelin (ng/mL) values revealed that, among EBL-positive cattle, the highest value was 2.77 ng/mL in Simmental cattle aged 2-8 years with a BCS of 3-3.5, while a value of 2.69 ng/mL was observed in Montafon cattle aged >8 years with a BCS of 3-3.5. For EBL-negative cattle, the highest mean serum apelin value was 2.24 ng/mL, recorded in Simmental cattle aged 2-8 years with a BCS of 3-3.5, whereas it was 1.45 ng/mL in Montafon cattle aged >8 years with the same BCS. In conclusion, this study demonstrated for the first time the effect of apelin hormone levels in cattle with or without EBL, depending on physiological parameters such as age, breed, and BCS. It is suggested that the apelin hormone, which is involved in neoplastic lymphocyte cell infiltration in the lymphoreticular tissues of cattle, and plays a role in regulating tumor growth in EBL, a malignant tumor disease, may contribute to eradication programs. Moreover, the evaluated parameters may prove valuable for disease prevention and control strategies.
- MakaleAçık Erişim2024Investigation of Microbiological, Physiological and Histopathological Changes in Polymicrobial I nfection in Old Rats
Ulker, U.; Kizil, S.; Bayraktar, B.; Alçigir, M. E.; Kul, O.; Kaya, H.; Ürüsan, H.; Aydemir, S.; Kotan, G. C.; Önel, A. U.
Background: The aim of this study is to examine the microbiological, clinical, physiological and pathological findings of natural polymicrobial infection developing in a wistar rat colony under long-term observation. Methods: In this study, 70 male Wistar albino rats, 3 years old, raised by conventional methods and housed in a cage environment were used. Thirteen rats with clinical symptoms such as torticollis and rotation were sacrificed for microbiological and histopathological examination after 14 days. For microbiological examination, the rapid diagnostic kit BBL Crystal system was used to identify bacterial agents in tissue and stool samples and the traditional culture method was used for isolation. Result: As a result of microbiological analysis, the rarely isolated Staphylococcus capitis ( S. capitis ) was isolated. Different Staphylococcus spp. It has been determined that the species can cause suppurative meningoencephalitis as well as septicemia in the brains of experimental animals., it is thought that polymicrobial infection will be useful for the identification of bacterial agents and infection prevention and treatment strategies.
- MakaleAçık Erişim2020Influence of lactobacillus reuteri on internal organ weight, performance and meat quality of Japanese quail (Coturnixcoturnix japonica) under heat stress; [Einfluss von lactobacillus reuteri auf das gewicht der inneren organe, die leistung und die fleischqualität Japanischer Wachteln (Coturnix coturnix japonica) unter Hitzestress]
Tekce, E.; Bayraktar, B.; Aksakal, V.; Dertli, E.; Kamiloğlu, A.; Çinar Topçu, K.; Kaya, H.; Takma, C.; Yasulergezer, N.
In the present study, the effects of Lactobacillus reuteri E81 (LRE) supplemented at different doses (200, 400 and 600 mg/kg) into the diets on performance, meat quality and internal organ weights of Japanese quail (Coturnixcoturnix japonica) were investigated under heat stress (HS) conditions (37°C). For the experiments, 448 one-day old quails were used. Seven days of training (physical exercise) and a 35-day fattening period were applied. On day 7 of the trial, 8 groups [4 under control temperature of 25°C (CT): control (C), LRE-200, LRE-400 and LRE-600 and 4 under HS: control (HSC), SLRE-200, SLRE-400 and SLRE-600] were formed, each group consisting of four replicates with 14 quail each. At the end of this study, the CT group fed 400 mg/kg LRE showed the best performance results, whereas no effect was found for groups under HS in comparison to the control group (HSC). Samples taken on the 21st and 42nd day revealed that addition of probiotics in the CT and HS groups induced no effect on weight of the internal organs (p > 0.05). Analysis of meat quality on the 21st day showed that LRE caused an increase in pH in both the HS and CT groups. Further, 400-mg/kg LRE supplementation induced an increase in thiobarbituric acid reactive substances (TBARS) in the group under HS. In the CT groups on day 42 no effect of LRE was found on colour parameters or on the TBARS value, except for a decrease in the pH value in the LRE supplemented groups compared with the control. In HS groups a decrease in the L* value and an increase in the TBARS value was found compared to CT groups (p < 0.05), but there was no effect on other colour parameters or pH value. In conclusion, in the present study supplementation of different doses of LRE E81 to quail diets had no effect on performance, internal organ weight or meat quality under HS.
- MakaleAçık Erişim2020Effects of lactobacillus reuteri e81 added into rations of chukar partridges (Alectoris chukar) fed under heat stress conditions on fattening performance and meat quality
Tekce, Emre; Bayraktar, B.; Aksakal, V.; Dertli, E.; Kamiloğlu, A.; Çinar, K.; Takma, Ç.; Kaya, H.; Gül, M.
This study investigated the effects of the addition of Lactobacillus reuteri E81 (LRE) into rations of chukar partridges (Alectoris chukar) fed under heat stress (HS) conditions on fattening performance and meat quality. This study included 256 chukar partridges aged 1 day. The study comprised an adaptation period of 7 days and a fattening period of 35 days and included 8 different groups with 32 animals in each group. Each group was further divided into four subgroups with eight animals in each subgroup. At the end of the study, the best results in terms of fattening performance in the non-HS groups were obtained in the LRE 600 ppm group and in the HS groups, SLRE 200 ppm had the best effect on average live weight and average live weight increase, whereas SLRE 400 ppm had the best effect on FCR (p<0.05). The analysis of the samples collected from chukar partridges on day 21 showed that, there was no effect on the colour parameters and Thiobarbituric acid reactive substances (TBARS) level in the LRE in the HS and non-HS groups, whereas the meat pH level decreased in the SLRE 400 ppm group (p<0.05). The analysis of the samples collected on day 42 showed that there was no effect on colour parameters in the HS and non-HS groups. TBARS level decreased at the dose of LRE 200 ppm in the non-HS group, and the meat pH level decreased in both HS and non-HS groups (p<0.05).