Sürdürülebilir Kalkınma Amaçları

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• MakaleYalnız künye2023/r/gumushane/16444
  Predicting hospitalization by TAPSE/SPAP and the role of spironolactone in asymptomatic heart failure patients

  Aydinyilmaz, Faruk; Guliyev, Ilkin; Özbeyaz, Nail B.; Algül, Engin; Aker, Mert; Sahan, Haluk F.; Erzurum, Muhammed; Felekoglu, Mehmet A.; Kalkan, Kamuran

  Aim: To appraise the prediction of tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (SPAP) with regard to hospitalization and the effect of spironolactone use. Materials & methods: A total of 245 patients were evaluated for the study. Patients were followed for 1 year and cardiovascular outcomes were determined. Results: It was determined that TAPSE/SPAP was an independent predictor of hospitalization. A 0.1-mmHg decrease in TAPSE/SPAP was associated with a 9% increase in relative risk. No event was observed above the 0.47 level. Negative correlation with TAPSE (uncoupling) began in the spironolactone group when SPAP was >= 43 and in nonusers when SPAP was 38 (Pearson's correlation coefficient: -,731 vs -,383; p < 0.001 vs p = 0.037). Conclusion: TAPSE/SPAP measurement may be useful in predicting 1-year hospitalization in asymptomatic heart failure patients. This ratio was also found to be higher in patients who used spironolactone.

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