Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2024/r/gumushane/10238
  Investigation of Microbiological, Physiological and Histopathological Changes in Polymicrobial I nfection in Old Rats

  Ulker, U.; Kizil, S.; Bayraktar, B.; Alçigir, M. E.; Kul, O.; Kaya, H.; Ürüsan, H.; Aydemir, S.; Kotan, G. C.; Önel, A. U.

  Background: The aim of this study is to examine the microbiological, clinical, physiological and pathological findings of natural polymicrobial infection developing in a wistar rat colony under long-term observation. Methods: In this study, 70 male Wistar albino rats, 3 years old, raised by conventional methods and housed in a cage environment were used. Thirteen rats with clinical symptoms such as torticollis and rotation were sacrificed for microbiological and histopathological examination after 14 days. For microbiological examination, the rapid diagnostic kit BBL Crystal system was used to identify bacterial agents in tissue and stool samples and the traditional culture method was used for isolation. Result: As a result of microbiological analysis, the rarely isolated Staphylococcus capitis ( S. capitis ) was isolated. Different Staphylococcus spp. It has been determined that the species can cause suppurative meningoencephalitis as well as septicemia in the brains of experimental animals., it is thought that polymicrobial infection will be useful for the identification of bacterial agents and infection prevention and treatment strategies.

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• MakaleAçık Erişim2023/r/gumushane/10623
  Relationship of progranulin response with some physio-biochemical parameters in Akkaraman sheep

  Bayraktar, Buelent; Tekce, Emre; Genç, Murat; Kaya, Hacer; Özcan, Gulbahar Boyuk; Aydemir, Seyma; Kotan, Goksad Cemil; Takma, Cigdem; Ürüsan, Hilal; Aksakal, Vecihi

  Progranulin (PGRN) is a multifunctional protein that is critical in the retention of embryos in the endometrium of the uterus and the protection of cervical tissue during fetal growth. In case of PGRN release and dysfunction, cervical tissue may remodel (regeneration) and lead to the risk of abortion. Serum PGRN level in sheep and its variation according to different physiological periods and its relationship with some biochemical parameters are unknown. In this study, the relationship between early lactation, early and late pregnancy serum PGRN levels and some biochemical parameters in Akkaraman sheep was investigated for the first time. In the literature search, no similar studies were found on the relationship between early lactation, early and late pregnancy serum PGRN levels and some biochemical parameters in Akkaraman sheep. The research was carried out on 90 Akkaraman sheep reared in the same herd under the same care and feeding conditions. In the study, Akkaraman ewe were divided into 3 groups as early lactation, early pregnancy and late pregnancy. 1st group is early lactation period ewe (first 60 days of lactation), (n = 30), 2nd group is in the first period of pregnancy (on the 0-90th day of the first pregnancy (n = 30)), 3rd group is in the late pregnancy of pregnancy (100-150 days of pregnancy (n = 30)) was created. Blood samples from vena jugularis were taken before morning feeding from the animals that formed the study groups. PGRN levels in serum were determined by ELISA method. In addition, glucose, calcium (Ca), magnesium (Mg), phosphorus (P), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL) levels were analyzed in biochemistry autoanalyzer. As a result of the study, lactation and early pregnancy and late pregnancy mean serum PGRN levels were determined as 1.93, 1.78, 1.33 ng mL-1, respectively. The serum PGRN, glucose, Ca, Mg, P, TC, TG, LDL, HDL and VLDL levels of sheep with late pregnancy, early lactation and early pregnancy periods, which constitute the study groups, were found to be statistically significant (P<0.05). Our results have shown that due to the physiological role of PRGN in keeping the embryo in the endometrium of the uterine and in preserving the cervical tissue during fetal growth, there may be a useful parameter in the pursuit of the pregnancy process.

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• MakaleAçık Erişim2018/r/gumushane/15318
  The effect of apple cider vinegar and mushroom stalk supplementation on laying hens

  Karaalp, Musa; Aksakal, Vecihi; Sarikaya, Sevim Beyza Ozturk; Urusan, Hilal; Bayram, Bahri; Zulkadir, Ayhan

  The aim of this trial was to study the effects of consuming water with apple cider vinegar (ACV) and feed including mushroom (Agaricus bisporus) stalk (MS) on performance and certain egg characteristics. The hens were separated into four treatment groups (with 4 replicates and 6 hens per replicate). The experimental groups were control (not consumed ACV and MS), ACV (3 ml/l drinking water), MS (20 g/kg feed) and ACV+MS (combination). At the end of the experiment, among the performance criteria tested, body weight, feed intake, egg production and weight of eggs, and feed efficiency were not affected by the treatments (P>0.05). Treatments had no effect on physical external and internal egg characteristics. The amount of yolk malondialdehyde of the ACV and MS groups was lower than the control group (P<0.05) in stored eggs (28 d) (P<0.05).

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