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  • MakaleAçık Erişim2026
    A Deep Learning–Based Framework for Automatic Determination of Developmental Dysplasia of the Hip from Graf Angles

    Taşolar, Sevgi; Günen, Mehmet Akif; Sığırcı, Ahmet; Taşolar, Hakan

    Developmental dysplasia of the hip (DDH) is a common neonatal condition that necessitates early diagnosis to ensure effective treatment. The traditional Graf method, while widely used for evaluating infant hips via ultrasound, is limited by operator dependency and measurement variability. This research has proposed a framework using deep learning network, morphological operation and local maxima method to diagnose DDH in newborns using ultrasound images. The method utilizes DeepLabv3 + for image segmentation, evaluating multiple backbone architectures (ResNet50, InceptionResNetV2, MobilenetV2, and Xception) to identify the region of interest accurately. Local maxima method was used to determine the extremum points of the line defining the Graf angles. Denoising filters, including mean, median, and Wiener, are applied to determine local maxima points accurately. The evaluation comprises two stages: first, assessing the performance of DeepLabv3 + backbones in producing masks for Graf angles determination, and second, comparing the angles obtained through proposed framework with those determined by expert radiologists. Comparative analysis demonstrates that MobileNetV2 (94.64 accuracy, 86.99 Cohen’s kappa, 94.31 F-score) surpasses other models in segmentation accuracy and measurement reliability. This conclusion is backed by key performance metrics such as accuracy, IoU, PSNR, F-score, SSIM, Cohen’s kappa, as well as by the intraclass correlation coefficient and Bland–Altman analyses. The proposed framework shows considerable promise in automating hip ultrasound analysis for DDH diagnosis, minimizing operator dependency while enhancing measurement consistency.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2024
    DL-EDOF: Novel Multi-Focus Image Data Set and Deep Learning-Based Approach for More Accurate and Specimen-Free Extended Depth of Focus

    Dogan, Hulya; Dogan, Ramazan Ozgur; Ay, Ilyas; Sezen, Sena F.

    Depth of focus (DOF) is defined as the axial range in which the specimen stage moves without losing focus while the imaging apparatus remains stable. It may not be possible to capture an image that includes the entire specimen in focus due to the narrow DOF in microscopic systems. Extended depth of focus (EDOF) is used to overcome this limitation in microscopic systems. Although the researchers have developed so many EDOF microscope approaches, this research field still has some crucial shortcomings such as high computational costs, complexity and execution time, requiring additional equipment, low precise characterization of curves, and edges in images, varying performance depending on the specimen and microscope, using only gray levels of input images to acquire the pixel’s focus values. In order to minimize these shortcomings and comprehensively analyze the performance of EDOF approaches, a novel multi-focus image data set is generated, and a deep learning-based EDOF microscope approach is proposed in this study. When compared with the state-of-art EDOF approaches, our study provides various crucial contributions such as the first EDOF approach based on unsupervised deep learning, providing more accurate and specimen-free EDOF, generating a novel multi-focus image data, not requiring any pre- or post-processing technique and acquiring the pixel’s focus degrees using deep features. In order to evaluate the effectiveness of the suggested approach, 20 different EDOF approaches are applied to a multi-focus image data set containing 9 image collections (4 synthetic and 5 microscope image collections) in total. Performance analysis metrics with and without requiring a reference image are preferred to identify which EDOF microscope approach can extract more essential details from the multi-focus images for the synthetic and microscope image collections, which are Root Mean Square Error (RMSE), Peak Signal Noise Ratio (PSNR), Universal Quality Index (UQI), Correlation Coefficient (CC), Perception-based Image Quality Evaluator (PIQE), Blind/Referenceless Image Spatial Quality Evaluator (BRISQUE), Extension of Universal Quality Index for N Images (UQIN), and Naturalness Image Quality Evaluator (NIQE). Objective and subjective analysis of this study demonstrates that unsupervised deep learning model is more efficient to transmit crucial details from multi-focus images. Moreover, the suggested EDOF microscope approach with highest PSNR, UQI, CC, UQIN and lowest RMSE, PIQE, BRISQUE, NIQE produces higher performance than the state-of-art approaches.

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AlanDeğerDil
creativeworkseries.issn2948-2933
dc.date.accessioned2026-10-22T10:21:33.948307708Z
dc.date.available2026-10-22T10:21:33.948307708Z
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/gumushane/13604
dc.publisherSpringer Nature
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleJournal of Imaging Informatics in Medicine
dspace.entity.typeJournal