Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2026/r/gumushane/12307
  A Personalized Target Placement Optimization Framework for VR-Based Upper Extremity Rehabilitation

  Türe, Hayati; Kalfa, Eren; Aslan, Muhammed Emin; Işık, Buket Özdemir; Topçu, Osman; Özdemir, Erhan; Sarıhan, Köksal

  Featured Application: The proposed framework can be directly integrated into existing VR rehabilitation platforms to provide real-time personalized target placement for post-stroke upper extremity therapy, requiring no additional hardware beyond a standard CPU. Virtual reality (VR)-based rehabilitation is an established modality for upper extremity motor recovery; however, existing systems frequently rely on fixed, random, or therapist-tuned target placement that disregards patient-specific motor capacity and population-level priors. This study proposes a cross-patient collaborative swarm intelligence framework that derives zone-based patient profiles from real VR trajectories and augments them with a similarity-weighted cohort prior distilled from clinically similar patients’ successful trajectory clouds and zone-transition graphs. A hybrid Ant Colony Optimization (ACO)–Particle Swarm Optimization (PSO) algorithm optimizes 12 targets per session across a 27-zone ( (Formula presented.) ) workspace using a five-component fitness function encompassing reachability, zone balance, movement efficiency, heatmap-guided challenge coverage, and swarm-flow consistency. The framework was evaluated retrospectively on a single-center cohort of 36 post-stroke patients and 6373 sessions under a leakage-safe simulation protocol with 70/30 chronological splits; outcomes are model-based proxy success rates derived from each patient’s profile rather than directly observed task success. The hybrid strategy achieved a mean simulated success rate of 85.5% ± 5.5%, a 36.4% relative improvement over random placement (Wilcoxon (Formula presented.), Cohen’s (Formula presented.) ); the leakage-safe split yielded 80.1% on the held-out segment versus 61.1% for random, with no statistically significant train–test gap ( (Formula presented.) ). Ablation confirmed both PSO and ACO are individually necessary ( (Formula presented.) pp, (Formula presented.) ). Total session-start computation is 78 ms on standard CPU hardware. These findings constitute a proof-of-concept that collaborative personalized swarm optimization can substantially outperform heuristic target placement under in silico evaluation; clinical efficacy in terms of standardized motor outcome measures remains to be established in a prospective randomized controlled trial, and the findings should be replicated across centers, task modes, and a larger cohort before generalization.

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• BildiriYalnız künye2025/r/gumushane/14012
  Hybrid CNN-LSTM Framework for Automated Detection of Pediatric Heart Murmurs

  Al-Taib, Asmaa Abduh; Ture, Hayati; Aslan, Muhammed Emin

  This study presents a comprehensive deep learning framework for automated heart murmur detection from phonocardiogram (PCG) signals to address the subjective limitations of cardiac auscultation. Using the CirCor DigiScope dataset of 5,272 pediatric heart sound recordings from 1,568 subjects, we systematically evaluated multiple approaches including traditional machine learning models (Logistic Regression, SVM, KNN, Decision Tree, AdaBoost), basic deep learning architectures (standalone CNN and LSTM), and advanced transfer learning models (DenseNet121, EfficientNet B0/B1/B2, ResNet 50/101, MobileNet V2/V3, GhostNet, AttentionCNN). Our hybrid CNN-LSTM architecture combines mel-spectrogram spatial feature extraction with temporal sequence modeling using 128 traditional audio features and comprehensive preprocessing with data augmentation. The CNN-LSTM model achieved superior performance with 84.6% accuracy, 0.84 F1-score, 0.748 precision, and 0.800 recall, significantly outperforming traditional methods (best SVM: 0.716 F1-score) and advanced architectures (best DenseNet121: 0.72 F1-score), demonstrating robust classification with 0.879 AUC. Results indicate that hybrid deep learning architectures effectively automate cardiac auscultation, providing objective diagnostic tools with potential for improved healthcare accessibility and clinical decision-making.

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