Sürdürülebilir Kalkınma Amaçları

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• MakaleYayıncıda açık erişim2026/r/gumushane/14219
  Innovation adoption of artificial meat among academic consumers in Turkey

  Dişli Bayraktar, Eda; Öztürk, Zeynep; Öztürk Küçük, Hilal

  Artificial meat has emerged as a promising sustainable food technology with the potential to mitigate environmental impacts associated with conventional livestock production. However, its societal diffusion largely depends on consumer acceptance and the adoption of this innovation. This study examines academics’ attitudes and consumption intentions toward artificial meat in Turkey by focusing on two innovation adoption tendencies novelty seeking and independent decision making and testing the mediating role of attitude within the Theory of Planned Behavior framework. Data were collected via an online questionnaire distributed through social media and email, yielding 277 valid responses from academics across different regions and faculties. Analyses were conducted using SPSS and Hayes’ PROCESS macro (Model 4) with 5,000 bootstrap samples (95% confidence intervals). Results indicate that attitude toward artificial meat is the strongest predictor of consumption intention. Novelty seeking positively predicts attitude, which in turn increases intention; when attitude is included, the direct effect of novelty seeking on intention becomes non-significant, indicating full mediation. In contrast, independent decision-making negatively predicts attitude and indirectly reduces consumption intention through attitude, also reflecting a full mediation structure. Descriptive findings further show high awareness but low willingness to try artificial meat among academics. Overall, the study highlights the central role of attitude in the adoption of innovative food technologies and suggests that communication strategies should prioritize attitude formation, particularly by addressing skepticism among autonomous decision-makers while engaging novelty-seeking individuals as potential early adopters.

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• MakaleAçık Erişim2026/r/gumushane/12099
  Evaluation of antioxidant and antiproliferative activities of shogaol and its modulatory effects on key metabolic enzymes

  Yapıcı, İsmail; Gülçin, İlhami

  Phenolic compounds are versatile bioactive molecules, particularly in food applications. In this study, the antioxidant capacity of Shogaol, a member of the phenolic class, was evaluated using several methods. Additionally, its inhibitory effects on human carbonic anhydrase I and II (hCA I and II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-glycosidase, and α-amylase enzymes, as well as its antiproliferative effects on A-549 lung cancer, HT-29 colon cancer, MCF-7 and MDA-MB-453 breast cancer cell lines, and the 3T3-L1 mouse fibroblast normal cell line, were investigated. To determine the antioxidant capacity of Shogaol, DPPH and ABTS radical scavenging assays, as well as Cu²⁺, Fe³⁺, and FRAP reduction methods, were employed. Its inhibitory effects on hCA I and II, AChE, BChE, α-glycosidase, and α-amylase enzymes were examined. Furthermore, cell counting was performed using the TBE method, and cell viability was measured with the XTT assay to assess the antiproliferative effects of Shogaol on A-549, HT-29, MCF-7, MDA-MB-453, and 3T3-L1 cell lines. Shogaol demonstrated higher antioxidant capacity than BHA, BHT, and Trolox in the FRAP assay (60 µg/mL), higher than BHT in the DPPH scavenging assay, and higher than Trolox in the ABTS, Cu²⁺, and Fe³⁺ reduction assays. Shogaol also exhibited significant inhibitory effects against hCA I, hCA II, AChE, BChE, and α-glycosidase, with IC₅₀ values of 75.91, 47.04, 37.44, 24.11, and 35.72 nM, respectively. Moreover, Shogaol showed a more potent antiproliferative effect than the standard chemotherapeutic drug Carboplatin in A-549 lung cancer and HT-29 colon cancer cell lines, and greater efficacy than Docetaxel in the MCF-7 breast cancer cell line.

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