Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2025/r/gumushane/10606
  Investigation of the relationship between apelin hormone response and some physiological parameters in enzootic bovine leukosis virus infected cattle

  Sait, A.; Bayraktar, B.; Korkmaz, S.; Genç, M.; Bayraktar, S.; Kotan, G. C.; Aydemir, S.; Takma, C.; Bülbül, A. S.; Aksakal, V

  Apelin is a hormone with lymphangiogenesis potential, associated with tumor growth and lymph node metastasis, and is reported to stimulate tumor vascularization. This study aimed to investigate the response of the apelin hormone in cattle with and without Enzootic Bovine Leukosis (EBL) infection, based on physiological parameters such as breed, age, and body condition score (BCS). A total of 120 Simmental and Montafon cattle of varying ages (<2, 2-8, and >8) and BCS categories (<2, 3-3.5, and >= 4) were included in the study. Serum apelin hormone levels were measured using the ELISA technique in blood samples collected from the neck vein ( Vena jugularis) of the animals. The analysis of mean serum apelin (ng/mL) values revealed that, among EBL-positive cattle, the highest value was 2.77 ng/mL in Simmental cattle aged 2-8 years with a BCS of 3-3.5, while a value of 2.69 ng/mL was observed in Montafon cattle aged >8 years with a BCS of 3-3.5. For EBL-negative cattle, the highest mean serum apelin value was 2.24 ng/mL, recorded in Simmental cattle aged 2-8 years with a BCS of 3-3.5, whereas it was 1.45 ng/mL in Montafon cattle aged >8 years with the same BCS. In conclusion, this study demonstrated for the first time the effect of apelin hormone levels in cattle with or without EBL, depending on physiological parameters such as age, breed, and BCS. It is suggested that the apelin hormone, which is involved in neoplastic lymphocyte cell infiltration in the lymphoreticular tissues of cattle, and plays a role in regulating tumor growth in EBL, a malignant tumor disease, may contribute to eradication programs. Moreover, the evaluated parameters may prove valuable for disease prevention and control strategies.

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• MakaleAçık Erişim2025/r/gumushane/13894
  Effects of hawthorn (Crataegus oxycantha) fruit extract on tibia bone properties in broiler chickens subjected to heat stress

  Kaya, H.; Karaalp, M.

  The purpose of this study was to examine the effects on tibia morphology, biomechanics, and mineral levels of varying dosages of hawthorn (Crataegus oxyacantha) fruit extract (HFE) addition to experimentally heat-stressed broiler drinking water. A 2x3 factorial experimental design was used to randomly assign 300 one-day-old male broilers to six experimental groups. The experimental groups included three different HFE additions (0, 0.2, and 0.4 mL/L) and two different ambient temperatures (24 and 35 °C). Each experimental group consisted of five replicates, with 10 chicks (initial body weight 38±4 g) per replicate. The study results indicated that heat stress (IIS) led to a decline in tibia dry weight, length, wet weight, volume, Seedor index, cortex thickness, shear force and shear stress, while concurrently resulting in an increase in dry matter percentage (P<0.05). Heat stress led to a decline in the levels of calcium (Ca), magnesium (Mg), copper (Cu), iron (Fe), zinc (Zn) and potassium (K) (P<0.05). The addition of HFE in the drinking water of broiler chickens exposed to HS did not significantly affect the morphological and biomechanical properties of the tibia. However, tibial Ca levels increased with the addition of 0.2 mL/L HFE, while Mg and Zn levels were elevated at both 0.2 and 0.4 mL/L HFE concentrations compared to the control group (P<0.05). In contrast, Fe and Mn levels decreased with 0.2 mL/L HFE supplementation, and K levels were reduced at both supplementation levels compared to the control (P<0.05). The findings suggest that the addition of 0.2 mL/L HFE to the drinking water of heat-stressed broiler chickens may be an effective and recommended strategy to enhance bone quality characteristics.

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• MakaleAçık Erişim2017/r/gumushane/15091
  Association of IGF and IGFBP2 gene polymorphisms with growth and egg traits in Atak-S laying hens

  Das, Huseyin; Tarim, B.; Demir, S.; Küçükkent, N.; Cengiz, S.; Tülek, E.; Aksakal, V.

  Atak-S laying hens are a high-performance hybrid obtained by crossing of the Rhode Island Red (RIR) X the Barred Plymouth Rock (BR) and are being produced in the Ankara Poultry Research Institute since 1997. Phenotypic and genetic improving studies are continuous for this hybrid. In this study three different SNPs, two from IGF1 and one from IGFBP2 genes, were examined in 150 Atak-S chickens. Genetic association of SNPs were compared to body weight and egg number till 32 weeks of age, body weight at sexual maturity, age at sexual maturity and also egg quality traits such as egg shell breaking strength, shell thickness, Haugh unit, albumen index, yolk index and shape index were statistically analyzed. Only IGF1(a) locus was in agreement with Hardy-Weinberg equilibrium, while, the rest of the loci were not. As a result of the comparisons performed to the three SNPs, it was determined that there was a significant association (P < 0.05) between the T364C haplotypes of the IGF1(b) locus and body weight at 32 weeks of age, but there was not any association to the other traits.

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